Denise C. Liotta - Publications

Emory University, Atlanta, GA 

185 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Epplin M, Mohan A, Harris L, Zhu Z, Strong KL, Bacsa J, Le P, Menaldino DS, Traynelis SF, Liotta DC. The Discovery of Dihydropyrrolo[1,2-a]pyrazin-3(4H)-one-Based Second-Generation GluN2C- and GluN2D-Selective Positive Allosteric Modulators (PAMs) of the N-Methyl-D-Aspartate (NMDA) Receptor. Journal of Medicinal Chemistry. PMID 32538088 DOI: 10.1021/Acs.Jmedchem.9B01733  0.76
2020 Pribut N, Kaiser TM, Wilson RJ, Jecs E, Dentmon ZW, Pelly S, Sharma SK, Bartsch P, Burger PB, Hwang S, Le T, Sourimant J, Yoon JJ, Plemper RK, Liotta DC. Accelerated Discovery of Potent Fusion Inhibitors for Respiratory Syncytial Virus. Acs Infectious Diseases. PMID 32275393 DOI: 10.1021/Acsinfecdis.9B00524  0.76
2020 McDaniel MJ, Ogden KK, Kell SA, Burger PB, Liotta DC, Traynelis SF. NMDA receptor channel gating control by the pre-M1 helix. The Journal of General Physiology. 152. PMID 32221541 DOI: 10.1085/Jgp.201912362  0.76
2020 Perszyk RE, Swanger SA, Shelley C, Khatri A, Fernandez-Cuervo G, Epplin MP, Zhang J, Le P, Bülow P, Garnier-Amblard E, Gangireddy PKR, Bassell GJ, Yuan H, Menaldino DS, Liotta DC, et al. Biased modulators of NMDA receptors control channel opening and ion selectivity. Nature Chemical Biology. PMID 31959964 DOI: 10.1038/S41589-019-0449-5  0.76
2019 Tahirovic YA, Pelly S, Jecs E, Miller EJ, Sharma SK, Liotta DC, Wilson LJ. Small molecule and peptide-based CXCR4 modulators as therapeutic agents. A patent review for the period from 2010 to 2018. Expert Opinion On Therapeutic Patents. PMID 31854208 DOI: 10.1080/13543776.2020.1707186  0.44
2019 Summer SL, Kell SA, Zhu Z, Moore R, Liotta DC, Myers SJ, Koszalka GW, Traynelis SF, Menaldino DS. Di-aryl Sulfonamide Motif Adds π-Stacking Bulk in Negative Allosteric Modulators of the NMDA Receptor. Acs Medicinal Chemistry Letters. 10: 248-254. PMID 30891121 DOI: 10.1021/Acsmedchemlett.8B00395  0.76
2019 Regan MC, Zhu Z, Yuan H, Myers SJ, Menaldino DS, Tahirovic YA, Liotta DC, Traynelis SF, Furukawa H. Structural elements of a pH-sensitive inhibitor binding site in NMDA receptors. Nature Communications. 10: 321. PMID 30659174 DOI: 10.2210/Pdb6E7S/Pdb  0.76
2019 Katzman BM, Cox BD, Prosser AR, Alcaraz AA, Murat B, Héroux M, Tebben A, Zhang Y, Schroeder GM, Snyder JP, Wilson LJ, Liotta DC. Tetrahydroisoquinoline CXCR4 Antagonists Adopt a Hybrid Binding Mode within the Peptide Subpocket of the CXCR4 Receptor. Acs Medicinal Chemistry Letters. 10: 67-73. PMID 30655949 DOI: 10.1021/Acsmedchemlett.8B00441  0.56
2018 Wells G, Yuan H, McDaniel MJ, Kusumoto H, Snyder JP, Liotta DC, Traynelis SF. The GluN2B-Glu413Gly NMDA receptor variant arising from a de novo GRIN2B mutation promotes ligand-unbinding and domain opening. Proteins. PMID 30168177 DOI: 10.1002/Prot.25595  0.76
2018 Nguyen HH, Kim MB, Wilson RJ, Butch C, Kuo KM, Miller EJ, Tahirovic YA, Jecs E, Truax VM, Wang T, Sum C, Cvijic ME, Schroeder GM, Wilson LJ, Liotta DC. Design, Synthesis, and Pharmacological Evaluation of Second-Generation Tetrahydroisoquinoline-Based CXCR4 Antagonists with Favorable ADME Properties. Journal of Medicinal Chemistry. PMID 30052039 DOI: 10.1021/Acs.Jmedchem.8B00450  0.48
2018 Kaiser TM, Burger PB, Butch CJ, Pelly S, Liotta DC. A Machine Learning Approach for Predicting HIV Reverse Transcriptase Mutation Susceptibility of Biologically Active Compounds. Journal of Chemical Information and Modeling. PMID 29953819 DOI: 10.1021/Acs.Jcim.7B00475  0.76
2018 Gibb A, Ogden KK, McDaniel MJ, Vance KM, Kell SA, Butch C, Burger P, Liotta DC, Traynelis SF. A structurally-derived model of subunit-dependent NMDA receptor function. The Journal of Physiology. PMID 29917241 DOI: 10.1113/Jp276093  0.76
2018 Tahirovic YA, Truax VM, Wilson RJ, Jecs E, Nguyen HH, Miller EJ, Kim MB, Kuo KM, Wang T, Sum CS, Cvijic ME, Schroeder GM, Wilson LJ, Liotta DC. Discovery of -Alkyl Piperazine Side Chain Based CXCR4 Antagonists with Improved Drug-like Properties. Acs Medicinal Chemistry Letters. 9: 446-451. PMID 29795757 DOI: 10.1021/Acsmedchemlett.8B00030  0.44
2018 Perszyk R, Katzman BM, Kusumoto H, Kell SA, Epplin MP, Tahirovic YA, Moore RL, Menaldino D, Burger P, Liotta DC, Traynelis SF. An NMDAR positive and negative allosteric modulator series share a binding site and are interconverted by methyl groups. Elife. 7. PMID 29792594 DOI: 10.7554/Elife.34711  0.76
2018 Jecs E, Miller EJ, Wilson RJ, Nguyen HH, Tahirovic YA, Katzman BM, Truax VM, Kim MB, Kuo KM, Wang T, Sum CS, Cvijic ME, Schroeder GM, Wilson LJ, Liotta DC. Synthesis of Novel Tetrahydroisoquinoline CXCR4 Antagonists with Rigidified Side-Chains. Acs Medicinal Chemistry Letters. 9: 89-93. PMID 29456793 DOI: 10.1021/Acsmedchemlett.7B00406  0.48
2018 Miller EJ, Jecs E, Truax VM, Katzman BM, Tahirovic YA, Wilson RJ, Kuo KM, Kim MB, Nguyen HH, Saindane MT, Zhao H, Wang T, Sum CS, Cvijic ME, Schroeder GM, ... ... Liotta DC, et al. Discovery of Tetrahydroisoquinoline-Containing CXCR4 Antagonists with Improved in vitro ADMET Properties. Journal of Medicinal Chemistry. PMID 29350534 DOI: 10.1021/Acs.Jmedchem.7B01420  0.48
2018 Wilson RJ, Jecs E, Miller EJ, Nguyen HH, Tahirovic YA, Truax VM, Kim MB, Kuo KM, Wang T, Sum CS, Cvijic ME, Paiva AA, Schroeder GM, Wilson LJ, Liotta DC. Synthesis and SAR of 1,2,3,4-Tetrahydroisoquinoline-Based CXCR4 Antagonists. Acs Medicinal Chemistry Letters. 9: 17-22. PMID 29348805 DOI: 10.1021/Acsmedchemlett.7B00381  0.44
2017 Swanger SA, Vance KM, Acker TM, Zimmerman SS, DiRaddo JO, Myers SJ, Bundgaard C, Mosley CA, Summer SL, Menaldino DS, Jensen HS, Liotta DC, Traynelis SF. A novel negative allosteric modulator selective for GluN2C/2D-containing NMDA receptors inhibits synaptic transmission in hippocampal interneurons. Acs Chemical Neuroscience. PMID 29043770 DOI: 10.1021/Acschemneuro.7B00329  0.76
2017 Strong KL, Epplin MP, Bacsa J, Butch CJ, Burger PB, Menaldino DS, Traynelis SF, Liotta DC. The Structure Activity Relationship of a Tetrahydroisoquinoline Class of N-Methyl-ᴅ-Aspartate Receptor Modulators that Potentiates GluN2B-Containing N-Methyl-ᴅ-Aspartate Receptors. Journal of Medicinal Chemistry. PMID 28586221 DOI: 10.1021/Acs.Jmedchem.7B00239  0.76
2016 Kim MB, Giesler KE, Tahirovic YA, Truax VM, Liotta DC, Wilson LJ. CCR5 receptor antagonists in preclinical to phase II clinical development for treatment of HIV. Expert Opinion On Investigational Drugs. PMID 27791451 DOI: 10.1080/13543784.2016.1254615  0.44
2016 Perszyk RE, DiRaddo JO, Strong KL, Low CM, Ogden KK, Khatri A, Vargish GA, Pelkey KA, Tricoire L, Liotta DC, Smith Y, McBain CJ, Traynelis SF. GluN2D-containing NMDA receptors mediate synaptic transmission in hippocampal interneurons and regulate interneuron activity. Molecular Pharmacology. PMID 27625038 DOI: 10.1124/Mol.116.105130  0.76
2016 Miller EJ, Mays SG, Baillie MT, Howard RB, Culver DG, Saindane M, Pruett ST, Holt JJ, Menaldino DS, Evers TJ, Reddy GP, Arrendale RF, Natchus MG, Petros JA, Liotta DC. Discovery of a Fluorinated Enigmol Analog with Enhanced in Vivo Pharmacokinetic and Anti-Tumor Properties. Acs Medicinal Chemistry Letters. 7: 537-42. PMID 27190606 DOI: 10.1021/Acsmedchemlett.6B00113  0.72
2015 Katzman BM, Perszyk RE, Yuan H, Tahirovic YA, Sotimehin AE, Traynelis SF, Liotta DC. A novel class of negative allosteric modulators of NMDA receptor function. Bioorganic & Medicinal Chemistry Letters. 25: 5583-8. PMID 26525866 DOI: 10.1016/J.Bmcl.2015.10.046  0.72
2015 Cox BD, Mehta AK, DiRaddo JO, Liotta DC, Wilson LJ, Snyder JP. Structural analysis of CXCR4 - Antagonist interactions using saturation-transfer double-difference NMR. Biochemical and Biophysical Research Communications. 466: 28-32. PMID 26301631 DOI: 10.1016/J.Bbrc.2015.08.084  0.56
2015 Cox BD, Prosser AR, Sun Y, Li Z, Lee S, Huang MB, Bond VC, Snyder JP, Krystal M, Wilson LJ, Liotta DC. Pyrazolo-Piperidines Exhibit Dual Inhibition of CCR5/CXCR4 HIV Entry and Reverse Transcriptase. Acs Medicinal Chemistry Letters. 6: 753-7. PMID 26191361 DOI: 10.1021/Acsmedchemlett.5B00036  0.72
2015 Zhao H, Prosser AR, Liotta DC, Wilson LJ. Discovery of novel N-aryl piperazine CXCR4 antagonists. Bioorganic & Medicinal Chemistry Letters. PMID 25935642 DOI: 10.1016/J.Bmcl.2015.04.036  0.72
2015 Zimmerman SS, Khatri A, Garnier-Amblard EC, Mullasseril P, Kurtkaya NL, Gyoneva S, Hansen KB, Traynelis SF, Liotta DC. Correction to "Design, synthesis, and structure-activity relationship of a novel series of GluN2C-selective potentiators". Journal of Medicinal Chemistry. 58: 2862. PMID 25738634 DOI: 10.1021/Acs.Jmedchem.5B00199  0.72
2015 Yuan H, Myers SJ, Wells G, Nicholson KL, Swanger SA, Lyuboslavsky P, Tahirovic YA, Menaldino DS, Ganesh T, Wilson LJ, Liotta DC, Snyder JP, Traynelis SF. Context-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects. Neuron. 85: 1305-18. PMID 25728572 DOI: 10.1016/J.Neuron.2015.02.008  0.72
2015 Baldwin PR, Reeves AZ, Powell KR, Napier RJ, Swimm AI, Sun A, Giesler K, Bommarius B, Shinnick TM, Snyder JP, Liotta DC, Kalman D. Monocarbonyl analogs of curcumin inhibit growth of antibiotic sensitive and resistant strains of Mycobacterium tuberculosis. European Journal of Medicinal Chemistry. 92: 693-9. PMID 25618016 DOI: 10.1016/J.Ejmech.2015.01.020  0.72
2015 Zhu S, Kisiel W, Lu YJ, Petersen LC, Ndungu JM, Moore TW, Parker ET, Sun A, Sarkaria JN, Snyder JP, Liotta DC, Brat DJ, El-Rayes BF, Shoji M. Visualizing cancer and response to therapy in vivo using Cy5.5-labeled factor VIIa and anti-tissue factor antibody. Journal of Drug Targeting. 23: 257-65. PMID 25510254 DOI: 10.3109/1061186X.2014.988217  0.72
2014 Zhu S, Kisiel W, Lu YJ, Petersen LC, Ndungu JM, Moore TW, Parker ET, Sun A, Liotta DC, El-Rayes BF, Brat DJ, Snyder JP, Shoji M. Tumor angiogenesis therapy using targeted delivery of Paclitaxel to the vasculature of breast cancer metastases. Journal of Drug Delivery. 2014: 865732. PMID 25574399 DOI: 10.1155/2014/865732  0.56
2014 Strong KL, Jing Y, Prosser AR, Traynelis SF, Liotta DC. NMDA receptor modulators: an updated patent review (2013-2014). Expert Opinion On Therapeutic Patents. 24: 1349-66. PMID 25351527 DOI: 10.1517/13543776.2014.972938  0.72
2014 Khatri A, Burger PB, Swanger SA, Hansen KB, Zimmerman S, Karakas E, Liotta DC, Furukawa H, Snyder JP, Traynelis SF. Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator. Molecular Pharmacology. 86: 548-60. PMID 25205677 DOI: 10.1124/Mol.114.094516  0.72
2014 Cox BD, Prosser AR, Katzman BM, Alcaraz AA, Liotta DC, Wilson LJ, Snyder JP. Anti-HIV small-molecule binding in the peptide subpocket of the CXCR4:CVX15 crystal structure. Chembiochem : a European Journal of Chemical Biology. 15: 1614-20. PMID 24990206 DOI: 10.1002/Cbic.201402056  0.72
2014 Hu H, Mao S, Bugrysheva JV, Pruett S, Liotta DC, Scott JR, Snyder JP. Group A streptococcus inhibitors by high-throughput virtual screening. European Journal of Medicinal Chemistry. 82: 120-6. PMID 24880231 DOI: 10.1016/J.Ejmech.2014.05.006  0.72
2014 Santangelo Freel RM, Ogden KK, Strong KL, Khatri A, Chepiga KM, Jensen HS, Traynelis SF, Liotta DC. Correction to Synthesis and Structure Activity Relationship of Tetrahydroisoquinoline-Based Potentiators of GluN2C and GluN2D Containing N-Methyl-d-aspartate Receptors. Journal of Medicinal Chemistry. 57: 4975. PMID 24878076 DOI: 10.1021/jm500710w  0.76
2014 Krumm SA, Yan D, Hovingh ES, Evers TJ, Enkirch T, Reddy GP, Sun A, Saindane MT, Arrendale RF, Painter G, Liotta DC, Natchus MG, von Messling V, Plemper RK. An orally available, small-molecule polymerase inhibitor shows efficacy against a lethal morbillivirus infection in a large animal model. Science Translational Medicine. 6: 232ra52. PMID 24739760 DOI: 10.1126/Scitranslmed.3008517  0.72
2014 DiRaddo JO, Miller EJ, Hathaway HA, Grajkowska E, Wroblewska B, Wolfe BB, Liotta DC, Wroblewski JT. A real-time method for measuring cAMP production modulated by Gαi/o-coupled metabotropic glutamate receptors. The Journal of Pharmacology and Experimental Therapeutics. 349: 373-82. PMID 24659805 DOI: 10.1124/Jpet.113.211532  0.72
2014 Zimmerman SS, Khatri A, Garnier-Amblard EC, Mullasseril P, Kurtkaya NL, Gyoneva S, Hansen KB, Traynelis SF, Liotta DC. Design, synthesis, and structure-activity relationship of a novel series of GluN2C-selective potentiators. Journal of Medicinal Chemistry. 57: 2334-56. PMID 24512267 DOI: 10.1021/Jm401695D  0.72
2014 Prosser AR, Liotta DC. One-pot transformation of esters to analytically pure ketones: Methodology and application in process development Tetrahedron Letters. DOI: 10.1016/J.Tetlet.2014.10.024  0.72
2013 Truax VM, Zhao H, Katzman BM, Prosser AR, Alcaraz AA, Saindane MT, Howard RB, Culver D, Arrendale RF, Gruddanti PR, Evers TJ, Natchus MG, Snyder JP, Liotta DC, Wilson LJ. Discovery of tetrahydroisoquinoline-based CXCR4 antagonists. Acs Medicinal Chemistry Letters. 4: 1025-30. PMID 24936240 DOI: 10.1021/Ml400183Q  0.72
2013 Moore TW, Sana K, Yan D, Krumm SA, Thepchatri P, Snyder JP, Marengo J, Arrendale RF, Prussia AJ, Natchus MG, Liotta DC, Plemper RK, Sun A. Synthesis and Metabolic Studies of Host Directed Inhibitors for Anti Viral Therapy. Acs Medicinal Chemistry Letters. 4: 762-767. PMID 23956816 DOI: 10.1021/Ml400166B  0.72
2013 Acker TM, Khatri A, Vance KM, Slabber C, Bacsa J, Snyder JP, Traynelis SF, Liotta DC. Structure-activity relationships and pharmacophore model of a noncompetitive pyrazoline containing class of GluN2C/GluN2D selective antagonists. Journal of Medicinal Chemistry. 56: 6434-56. PMID 23909910 DOI: 10.1021/Jm400652R  0.72
2013 Santangelo Freel RM, Ogden KK, Strong KL, Khatri A, Chepiga KM, Jensen HS, Traynelis SF, Liotta DC. Synthesis and structure activity relationship of tetrahydroisoquinoline-based potentiators of GluN2C and GluN2D containing N-methyl-D-aspartate receptors. Journal of Medicinal Chemistry. 56: 5351-81. PMID 23627311 DOI: 10.1021/Jm400177T  0.72
2013 Brown A, Shi Q, Moore TW, Yoon Y, Prussia A, Maddox C, Liotta DC, Shim H, Snyder JP. Monocarbonyl curcumin analogues: heterocyclic pleiotropic kinase inhibitors that mediate anticancer properties. Journal of Medicinal Chemistry. 56: 3456-66. PMID 23550937 DOI: 10.1021/Jm4002692  0.72
2013 Moore TW, Sana K, Yan D, Thepchatri P, Ndungu JM, Saindane MT, Lockwood MA, Natchus MG, Liotta DC, Plemper RK, Snyder JP, Sun A. Asymmetric synthesis of host-directed inhibitors of myxoviruses. Beilstein Journal of Organic Chemistry. 9: 197-203. PMID 23400228 DOI: 10.3762/Bjoc.9.23  0.72
2012 Guthrie DB, Stein DG, Liotta DC, Lockwood MA, Sayeed I, Atif F, Arrendale RF, Reddy GP, Evers TJ, Marengo JR, Howard RB, Culver DG, Natchus MG. Water-soluble progesterone analogues are effective, injectable treatments in animal models of traumatic brain injury. Acs Medicinal Chemistry Letters. 3: 362-6. PMID 24900479 DOI: 10.1021/Ml200303R  0.72
2012 Meyer EV, Holt JJ, Girard KR, Ballie MT, Bushnev AS, Lapp S, Menaldino DS, Arrendale RF, Reddy GP, Evers TJ, Howard RB, Culver DG, Liotta DC, Galinski MR, Natchus MG. Sphingolipid analogues inhibit development of malaria parasites. Acs Medicinal Chemistry Letters. 3: 43-7. PMID 24900369 DOI: 10.1021/Ml2002136  0.72
2012 Santangelo RM, Acker TM, Zimmerman SS, Katzman BM, Strong KL, Traynelis SF, Liotta DC. Novel NMDA receptor modulators: an update. Expert Opinion On Therapeutic Patents. 22: 1337-52. PMID 23009122 DOI: 10.1517/13543776.2012.728587  0.72
2012 Burger PB, Yuan H, Karakas E, Geballe M, Furukawa H, Liotta DC, Snyder JP, Traynelis SF. Mapping the binding of GluN2B-selective N-methyl-D-aspartate receptor negative allosteric modulators. Molecular Pharmacology. 82: 344-59. PMID 22596351 DOI: 10.1124/Mol.112.078568  0.72
2012 Kim J, Wang L, Li Y, Becnel KD, Frey KM, Garforth SJ, Prasad VR, Schinazi RF, Liotta DC, Anderson KS. Pre-steady state kinetic analysis of cyclobutyl derivatives of 2′-deoxyadenosine 5′-triphosphate as inhibitors of HIV-1 reverse transcriptase Bioorganic and Medicinal Chemistry Letters. 22: 4064-4067. PMID 22595174 DOI: 10.1016/J.Bmcl.2012.04.078  0.72
2012 Liang Z, Zhan W, Zhu A, Yoon Y, Lin S, Sasaki M, Klapproth JM, Yang H, Grossniklaus HE, Xu J, Rojas M, Voll RJ, Goodman MM, Arrendale RF, Liu J, ... Liotta DC, et al. Development of a unique small molecule modulator of CXCR4. Plos One. 7: e34038. PMID 22485156 DOI: 10.1371/Journal.Pone.0034038  0.72
2012 Ndungu JM, Krumm SA, Yan D, Arrendale RF, Reddy GP, Evers T, Howard R, Natchus MG, Saindane MT, Liotta DC, Plemper RK, Snyder JP, Sun A. Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase: synthesis, structure-activity relationships, and pharmacokinetics. Journal of Medicinal Chemistry. 55: 4220-30. PMID 22480182 DOI: 10.1021/Jm201699W  0.72
2012 Boyle GA, Edlin CD, Li Y, Liotta DC, Morgans GL, Musonda CC. Enantioselective synthesis of the carbocyclic nucleoside (-)-abacavir Organic and Biomolecular Chemistry. 10: 1870-1876. PMID 22274412 DOI: 10.1039/C2Ob06775G  0.72
2012 Olivera A, Moore TW, Hu F, Brown AP, Sun A, Liotta DC, Snyder JP, Yoon Y, Shim H, Marcus AI, Miller AH, Pace TW. Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties. International Immunopharmacology. 12: 368-77. PMID 22197802 DOI: 10.1016/J.Intimp.2011.12.009  0.72
2012 Hassam M, Basson AE, Liotta DC, Morris L, Van Otterlo WAL, Pelly SC. Novel cyclopropyl-indole derivatives as HIV non-nucleoside reverse transcriptase inhibitors Acs Medicinal Chemistry Letters. 3: 470-475. DOI: 10.1021/ml3000462  0.72
2011 Garnier-Amblard EC, Mays SG, Arrendale RF, Baillie MT, Bushnev AS, Culver DG, Evers TJ, Holt JJ, Howard RB, Liebeskind LS, Menaldino DS, Natchus MG, Petros JA, Ramaraju H, Reddy GP, Liotta DC, et al. Novel synthesis and biological evaluation of enigmols as therapeutic agents for treating prostate cancer. Acs Medicinal Chemistry Letters. 2: 438-43. PMID 24900327 DOI: 10.1021/Ml2000164  0.52
2011 Zhan W, Jiang Y, Sharma S, Brodie PJ, Bane S, Kingston DG, Liotta DC, Snyder JP. C6-C8 bridged epothilones: consequences of installing a conformational lock at the edge of the macrocycle. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 14792-804. PMID 22127984 DOI: 10.1002/Chem.201102630  0.72
2011 Acker TM, Yuan H, Hansen KB, Vance KM, Ogden KK, Jensen HS, Burger PB, Mullasseril P, Snyder JP, Liotta DC, Traynelis SF. Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators. Molecular Pharmacology. 80: 782-95. PMID 21807990 DOI: 10.1124/Mol.111.073239  0.72
2011 Symolon H, Bushnev A, Peng Q, Ramaraju H, Mays SG, Allegood JC, Pruett ST, Sullards MC, Dillehay DL, Liotta DC, Merrill AH. Enigmol: A novel sphingolipid analogue with anticancer activity against cancer cell lines and in vivo models for intestinal and prostate cancer Molecular Cancer Therapeutics. 10: 648-657. PMID 21398423 DOI: 10.1158/1535-7163.Mct-10-0754  0.72
2011 Garnier-Amblard EC, Mays SG, Arrendale RF, Baillie MT, Bushnev AS, Culver DG, Evers TJ, Holt JJ, Howard RB, Liebeskind LS, Menaldino DS, Natchus MG, Petros JA, Ramaraju H, Reddy GP, Liotta DC, et al. Novel synthesis and biological evaluation of enigmols as therapeutic agents for treating prostate cancer Acs Medicinal Chemistry Letters. 2: 438-443. DOI: 10.1021/ml2000164  0.72
2011 Wilson LJ, Liotta DC. Emergence of small-molecule CXCR4 antagonists as novel immune and hematopoietic system regulatory agents Drug Development Research. 72: 598-602. DOI: 10.1002/Ddr.20469  0.72
2010 Zhu A, Zhan W, Liang Z, Yoon Y, Yang H, Grossniklaus HE, Xu J, Rojas M, Lockwood M, Snyder JP, Liotta DC, Shim H. Dipyrimidine amines: A novel class of chemokine receptor type 4 antagonists with high specificity Journal of Medicinal Chemistry. 53: 8556-8568. PMID 21105715 DOI: 10.1021/Jm100786G  0.72
2010 Heathcote DA, Patel H, Kroll SH, Hazel P, Periyasamy M, Alikian M, Kanneganti SK, Jogalekar AS, Scheiper B, Barbazanges M, Blum A, Brackow J, Siwicka A, Pace RD, Fuchter MJ, ... Liotta DC, et al. A novel pyrazolo[1,5-a]pyrimidine is a potent inhibitor of cyclin-dependent protein kinases 1, 2, and 9, which demonstrates antitumor effects in human tumor xenografts following oral administration. Journal of Medicinal Chemistry. 53: 8508-22. PMID 21080703 DOI: 10.1021/Jm100732T  0.72
2010 Mullasseril P, Hansen KB, Vance KM, Ogden KK, Yuan H, Kurtkaya NL, Santangelo R, Orr AG, Le P, Vellano KM, Liotta DC, Traynelis SF. A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors. Nature Communications. 1: 90. PMID 20981015 DOI: 10.1038/Ncomms1085  0.72
2010 Tan X, Sidell N, Mancini A, Huang RP, Shenming Wang, Horowitz IR, Liotta DC, Taylor RN, Wieser F. Multiple anticancer activities of EF24, a novel curcumin analog, on human ovarian carcinoma cells Reproductive Sciences. 17: 931-940. PMID 20693500 DOI: 10.1177/1933719110374239  0.72
2010 Mosley CA, Acker TM, Hansen KB, Mullasseril P, Andersen KT, Le P, Vellano KM, Bräuner-Osborne H, Liotta DC, Traynelis SF. Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists. Journal of Medicinal Chemistry. 53: 5476-90. PMID 20684595 DOI: 10.1021/Jm100027P  0.72
2010 Bhosle S, Suppiah S, Molinaro R, Liang Y, Arnold R, Diehl W, Makarova N, Blackwell J, Petros J, Liotta D, Hunter E, Ly H. Evaluation of cellular determinants required for in vitro xenotropic murine leukemia virus-related virus entry into human prostate cancer and noncancerous cells. Journal of Virology. 84: 6288-96. PMID 20410264 DOI: 10.1128/Jvi.00274-10  0.72
2010 Li Y, Soni PB, Liu L, Zhang X, Liotta DC, Lutz S. Synthesis of fluorescent nucleoside analogs as probes for 2′-deoxyribonucleoside kinases Bioorganic and Medicinal Chemistry Letters. 20: 841-843. PMID 20060716 DOI: 10.1016/J.Bmcl.2009.12.097  0.72
2010 Pandey KK, Snyder JP, Liotta DC, Musaev DG. Computational studies of transition metal selectivity of octapeptide repeat region of prion protein (PrP). The Journal of Physical Chemistry. B. 114: 1127-35. PMID 20020721 DOI: 10.1021/Jp909945E  0.56
2010 Liotta D. Introductory editorial for ACS medicinal chemistry letters Acs Medicinal Chemistry Letters. 1: 1. DOI: 10.1021/Ml100054Q  0.72
2010 Pandey KK, Snyder JP, Liotta DC, Musaev DG. Computational Studies of Transition Metal Selectivity of Octapeptide Repeat Region of Prion Protein (PrP) Journal of Physical Chemistry B. 114: 1127-1135. DOI: 10.1021/jp909945e  0.72
2009 Sun A, Lu YJ, Hu H, Shoji M, Liotta DC, Snyder JP. Curcumin analog cytotoxicity against breast cancer cells: exploitation of a redox-dependent mechanism Bioorganic and Medicinal Chemistry Letters. 19: 6627-6631. PMID 19854644 DOI: 10.1016/J.Bmcl.2009.10.023  0.72
2009 Thepchatri P, Min J, Ganesh T, Du Y, Lewis I, Kurtkaya S, Prussia A, Li L, Sneed B, Plemper RK, Fu H, Liotta DC, Snyder JP, Dingledine R, Sun A. Cancer and virus leads by HTS, chemical design and SEA data mining. Current Topics in Medicinal Chemistry. 9: 1159-71. PMID 19807668 DOI: 10.2174/156802609789753581  0.72
2009 MacNevin CJ, Atif F, Sayeed I, Stein DG, Liotta DC. Development and screening of water-soluble analogues of progesterone and allopregnanolone in models of brain injury. Journal of Medicinal Chemistry. 52: 6012-23. PMID 19791804 DOI: 10.1021/Jm900712N  0.72
2009 Mosley CA, Myers SJ, Murray EE, Santangelo R, Tahirovic YA, Kurtkaya N, Mullasseril P, Yuan H, Lyuboslavsky P, Le P, Wilson LJ, Yepes M, Dingledine R, Traynelis SF, Liotta DC. Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-D-aspartate receptors. Bioorganic & Medicinal Chemistry. 17: 6463-80. PMID 19648014 DOI: 10.1016/J.Bmc.2009.05.085  0.72
2009 Ali S, Heathcote DA, Kroll SH, Jogalekar AS, Scheiper B, Patel H, Brackow J, Siwicka A, Fuchter MJ, Periyasamy M, Tolhurst RS, Kanneganti SK, Snyder JP, Liotta DC, Aboagye EO, et al. The development of a selective cyclin-dependent kinase inhibitor that shows antitumor activity. Cancer Research. 69: 6208-15. PMID 19638587 DOI: 10.1158/0008-5472.Can-09-0301  0.72
2009 Liu L, Li Y, Liotta D, Lutz S. Directed evolution of an orthogonal nucleoside analog kinase via fluorescence-activated cell sorting. Nucleic Acids Research. 37: 4472-81. PMID 19474348 DOI: 10.1093/Nar/Gkp400  0.72
2009 Mosley CA, Wilson LJ, Wiseman JM, Skudlarek JW, Liotta DC. Recent patents regarding the discovery of small molecule CXCR4 antagonists. Expert Opinion On Therapeutic Patents. 19: 23-38. PMID 19441896 DOI: 10.1517/13543770802553483  0.72
2008 Tahirovic YA, Geballe M, Gruszecka-Kowalik E, Myers SJ, Lyuboslavsky P, Le P, French A, Irier H, Choi WB, Easterling K, Yuan H, Wilson LJ, Kotloski R, McNamara JO, Dingledine R, Liotta DC, et al. Enantiomeric propanolamines as selective N-methyl-D-aspartate 2B receptor antagonists. Journal of Medicinal Chemistry. 51: 5506-21. PMID 18800760 DOI: 10.1021/Jm8002153  0.72
2008 Ganesh T, Min J, Thepchatri P, Du Y, Li L, Lewis I, Wilson L, Fu H, Chiosis G, Dingledine R, Liotta D, Snyder JP, Sun A. Discovery of aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90): Synthesis, biology, and molecular modeling. Bioorganic & Medicinal Chemistry. 16: 6903-10. PMID 18571929 DOI: 10.1016/J.Bmc.2008.05.047  0.72
2008 Pruett ST, Bushnev A, Hagedorn K, Adiga M, Haynes CA, Sullards MC, Liotta DC, Merrill AH. Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols Journal of Lipid Research. 49: 1621-1639. PMID 18499644 DOI: 10.1194/Jlr.R800012-Jlr200  0.72
2008 Shoji M, Sun A, Kisiel W, Lu YJ, Shim H, McCarey BE, Nichols C, Parker ET, Pohl J, Mosley CA, Alizadeh AR, Liotta DC, Snyder JP. Targeting tissue factor-expressing tumor angiogenesis and tumors with EF24 conjugated to factor VIIa. Journal of Drug Targeting. 16: 185-97. PMID 18365880 DOI: 10.1080/10611860801890093  0.72
2008 Zhan W, Jiang Y, Brodie PJ, Kingston DGI, Liotta DC, Snyder JP. Design and synthesis C6-C8 bridged epothilone a Organic Letters. 10: 1565-1568. PMID 18355076 DOI: 10.1021/Ol800422Q  0.72
2008 MacNevin CJ, Moore RL, Liotta DC. Stereoselective synthesis of quaternary center bearing azetines and their β-amino acid derivatives Journal of Organic Chemistry. 73: 1264-1269. PMID 18186644 DOI: 10.1021/Jo7018202  0.72
2007 Zhan W, Liang Z, Zhu A, Kurtkaya S, Shim H, Snyder JP, Liotta DC. Discovery of small molecule CXCR4 antagonists Journal of Medicinal Chemistry. 50: 5655-5664. PMID 17958344 DOI: 10.1021/Jm070679I  0.72
2007 Mosley CA, Liotta DC, Snyder JP. Highly active anticancer curcumin analogues. Advances in Experimental Medicine and Biology. 595: 77-103. PMID 17569206 DOI: 10.1007/978-0-387-46401-5_2  0.72
2007 Li Y, Mao S, Hager MW, Becnel KD, Schinazi RF, Liotta DC. Synthesis and evaluation of 2′-substituted cyclobutyl nucleosides and nucleotides as potential anti-HIV agents Bioorganic and Medicinal Chemistry Letters. 17: 3398-3401. PMID 17434736 DOI: 10.1016/J.Bmcl.2007.03.094  0.72
2006 Sun A, Prussia A, Zhan W, Murray EE, Doyle J, Cheng LT, Yoon JJ, Radchenko EV, Palyulin VA, Compans RW, Liotta DC, Plemper RK, Snyder JP. Nonpeptide inhibitors of measles virus entry Journal of Medicinal Chemistry. 49: 5080-5092. PMID 16913698 DOI: 10.1021/Jm0602559  0.72
2006 Sun A, Shoji M, Lu YJ, Liotta DC, Snyder JP. Synthesis of EF24-tripeptide chloromethyl ketone: A novel curcumin-related anticancer drug delivery system Journal of Medicinal Chemistry. 49: 3153-3158. PMID 16722634 DOI: 10.1021/Jm051141K  0.72
2006 Doyle J, Prussia A, White LK, Sun A, Liotta DC, Snyder JP, Compans RW, Plemper RK. Two domains that control prefusion stability and transport competence of the measles virus fusion protein. Journal of Virology. 80: 1524-36. PMID 16415028 DOI: 10.1128/Jvi.80.3.1524-1536.2006  0.72
2006 Herold-Dublin M, Liotta DC. Diastereoselective addition of chlorotitanium enolates of N-acyl thiazolidinethione to activated imines - A novel synthesis of β-lactams Canadian Journal of Chemistry. 84: 1696-1699. DOI: 10.1139/V06-179  0.72
2005 Plemper RK, Doyle J, Sun A, Prussia A, Cheng LT, Rota PA, Liotta DC, Snyder JP, Compans RW. Design of a small-molecule entry inhibitor with activity against primary measles virus strains Antimicrobial Agents and Chemotherapy. 49: 3755-3761. PMID 16127050 DOI: 10.1128/Aac.49.9.3755-3761.2005  0.72
2005 Hernandez-Santiago BI, Chen H, Asif G, Beltran T, Mao S, Hurwitz SJ, Grier J, McClure HM, Chu CK, Liotta DC, Schinazi RF. Pharmacology and pharmacokinetics of the antiviral agent β-D-2′,3′-dideoxy-3′-oxa-5-fluorocytidine in cells and rhesus monkeys Antimicrobial Agents and Chemotherapy. 49: 2589-2597. PMID 15980324 DOI: 10.1128/Aac.49.7.2589-2597.2005  0.72
2005 Adams BK, Cai J, Armstrong J, Herold M, Lu YJ, Sun A, Snyder JP, Liotta DC, Jones DP, Shoji M. EF24, a novel synthetic curcumin analog, induces apoptosis in cancer cells via a redox-dependent mechanism Anti-Cancer Drugs. 16: 263-275. PMID 15711178 DOI: 10.1097/00001813-200503000-00005  0.72
2004 Mao S, Bouygues M, Welch C, Biba M, Chilenski J, Schinazi RF, Liotta DC. Synthesis of enantiomerically pure D-FDOC, an anti-HIV agent Bioorganic and Medicinal Chemistry Letters. 14: 4991-4994. PMID 15341966 DOI: 10.1016/J.Bmcl.2004.07.016  0.72
2004 Adams BK, Ferstl EM, Davis MC, Herold M, Kurtkaya S, Camalier RF, Hollingshead MG, Kaur G, Sausville EA, Rickles FR, Snyder JP, Liotta DC, Shoji M. Synthesis and biological evaluation of novel curcumin analogs as anti-cancer and anti-angiogenesis agents Bioorganic and Medicinal Chemistry. 12: 3871-3883. PMID 15210154 DOI: 10.1016/J.Bmc.2004.05.006  0.72
2004 Painter GR, Almond MR, Mao S, Liotta DC. Biochemical and mechanistic basis for the activity of nucleoside analogue inhibitors of HIV reverse transcriptase Current Topics in Medicinal Chemistry. 4: 1035-1044. PMID 15193137 DOI: 10.2174/1568026043388358  0.72
2004 Plemper RK, Erlandson KJ, Lakdawala AS, Sun A, Prussia A, Boonsombat J, Aki-Sener E, Yalcin I, Yildiz I, Temiz-Arpaci O, Tekiner B, Liotta DC, Snyder JP, Compans RW. A target site for template-based design of measles virus entry inhibitors Proceedings of the National Academy of Sciences of the United States of America. 101: 5628-5633. PMID 15056763 DOI: 10.1073/Pnas.0308520101  0.72
2004 Ambhaikar NB, Herold M, Liotta DC. A uniquely accessible route to the diastereoselective synthesis of azetine derivatives Heterocycles. 62: 217-222. DOI: 10.3987/Com-03-S(P)56  0.72
2003 Menaldino DS, Bushnev A, Sun A, Liotta DC, Symolon H, Desai K, Dillehay DL, Peng Q, Wang E, Allegood J, Trotman-Pruett S, Sullards MC, Merrill AH. Sphingoid bases and de novo ceramide synthesis: Enzymes involved, pharmacology and mechanisms of action Pharmacological Research. 47: 373-381. PMID 12676511 DOI: 10.1016/S1043-6618(03)00054-9  0.72
2003 Ambhaikar NB, Snyder JP, Liotta DC. Diastereoselective addition of chlorotitanium enolate of N-acyl thiazolidinethione to O-methyl oximes: A novel, stereoselective synthesis of α,β-disubstituted β-amino carbonyl compounds via chiral auxiliary mediated azetine formation Journal of the American Chemical Society. 125: 3690-3691. PMID 12656586 DOI: 10.1021/Ja029871U  0.72
2003 Painter GR, Rimsky LT, Furman PA, Liotta DC, Schinazi RF, Quinn JB. Preclinical and clinical development of the anti-HIV, anti-HBV oxathiolane nucleoside analog emtricitabine Frontiers in Viral Hepatitis. 451-484. DOI: 10.1016/B978-044450986-4/50088-6  0.72
2002 Desai K, Sullards MC, Allegood J, Wang E, Schmelz EM, Hartl M, Humpf HU, Liotta DC, Peng Q, Merrill AH. Fumonisins and fumonisin analogs as inhibitors of ceramide synthase and inducers of apoptosis Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids. 1585: 188-192. PMID 12531553 DOI: 10.1016/S1388-1981(02)00340-2  0.72
2002 Lakdawala AS, Morgan DM, Liotta DC, Lynn DG, Snyder JP. Dynamics and fluidity of amyloid fibrils: a model of fibrous protein aggregates. Journal of the American Chemical Society. 124: 15150-1. PMID 12487571 DOI: 10.1021/Ja0273290  0.72
2002 Schinazi RF, Mellors J, Bazmi H, Diamond S, Garber S, Gallagher K, Geleziunas R, Klabe R, Pierce M, Rayner M, Wu JT, Zhang H, Hammond J, Bacheler L, Manion DJ, ... Liotta DC, et al. DPC 817: a cytidine nucleoside analog with activity against zidovudine- and lamivudine-resistant viral variants. Antimicrobial Agents and Chemotherapy. 46: 1394-401. PMID 11959574 DOI: 10.1128/Aac.46.5.1394-1401.2002  0.72
2002 Ferstl EM, Venkatesan H, Ambhaikar NB, Snyder JP, Liotta DC. Thiazolidine-2-thione directed diastereoselective addition of chlorotitanium enolates to aldimines Synthesis. 2075-2083. DOI: 10.1055/S-2002-34375  0.72
2002 Morgan DM, Lynn DG, Lakdawala AS, Snyder JP, Liotta DC. Amyloid structure: Models and theoretical considerations in fibrous aggregates Journal of the Chinese Chemical Society. 49: 459-466. DOI: 10.1002/Jccs.200200072  0.72
2001 Lakdawala A, Wang M, Nevins N, Liotta DC, Rusinska-Roszak D, Lozynski M, Snyder JP. Calculated conformer energies for organic molecules with multiple polar functionalities are method dependent: Taxol (case study). Bmc Chemical Biology. 1: 2. PMID 11710970 DOI: 10.1186/1472-6769-1-2  0.56
2001 Judd DA, Nettles JH, Nevins N, Snyder JP, Liotta DC, Tang J, Ermolieff J, Schinazi RF, Hill CL. Polyoxometalate HIV-1 protease inhibitors. A new mode of protease inhibition Journal of the American Chemical Society. 123: 886-897. PMID 11456622 DOI: 10.1021/Ja001809E  0.72
2001 Venkatesan H, Davis MC, Altas Y, Snyder JP, Liotta DC. Total synthesis of SR 121463 A, a highly potent and selective vasopressin V2 receptor antagonist Journal of Organic Chemistry. 66: 3653-3661. PMID 11374981 DOI: 10.1021/Jo0004658  0.72
2000 Wang M, Cornett B, Nettles J, Liotta DC, Snyder JP. The oxetane ring in Taxol Journal of Organic Chemistry. 65: 1059-1068. PMID 10814054 DOI: 10.1021/Jo9916075  0.72
2000 Schinazi RF, Hurwitz SJ, Liberman I, Juodawlkis AS, Tharnish P, Shi J, Liotta DC, Coderre JA, Olson J. Treatment of isografted 9L rat brain tumors with β-5-o-carboranyl-2'- deoxyuridine neutron capture therapy Clinical Cancer Research. 6: 725-730. PMID 10690559  0.72
1999 Wang M, Xia X, Kim Y, Hwang D, Jansen JM, Botta M, Liotta DC, Snyder JP. A unified and quantitative receptor model for the microtubule binding of paclitaxel and epothilone Organic Letters. 1: 43-46. PMID 10822530 DOI: 10.1021/Ol990521V  0.72
1999 Schmelz EM, Bushnev AS, Dillehay DL, Sullards MC, Liotta DC, Merrill AH. Ceramide-β-D-glucuronide: Synthesis, digestion, and suppression of early markers of colon carcinogenesis Cancer Research. 59: 5768-5772. PMID 10582697  0.72
1999 Warden LA, Menaldino DS, Wilson T, Liotta DC, Smith ER, Merrill AH. Identification of ammonium ion and 2,6-bis(ω-aminobutyl)-3,5- diiminopiperazine as endogenous factors that account for the 'burst' of sphingosine upon changing the medium of J774 cells in culture Journal of Biological Chemistry. 274: 33875-33880. PMID 10567348 DOI: 10.1074/Jbc.274.48.33875  0.72
1999 Bushnev AS, Liotta DC. Practical synthesis of N-palmitoylsphingomyelin and N- palmitoyldihydrosphingomyelin Methods in Enzymology. 311: 535-547. PMID 10563348 DOI: 10.1016/S0076-6879(00)11104-8  0.72
1999 Shi J, McAtee JJ, Wirtz SS, Tharnish P, Juodawlkis A, Liotta DC, Schinazi RF. Synthesis and biological evaluation of 2',3'-didehydro-2',3'-dideoxy-5- fluorocytidine (D4FC) analogues: Discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase Journal of Medicinal Chemistry. 42: 859-867. PMID 10072683 DOI: 10.1021/Jm980510S  0.72
1999 Ma L, Hurwitz SJ, Shi J, Mcatee JJ, Liotta DC, McClure HM, Schinazi RF. Pharmacokinetics of the antiviral agent β-D-2',3'-didehydro- 2',3'- dideoxy-5-fluorocytidine in rhesus monkeys Antimicrobial Agents and Chemotherapy. 43: 381-384. PMID 9925539 DOI: 10.1128/Aac.43.2.381  0.72
1998 Birt DF, Merrill AH, Barnett T, Enkvetchakul B, Pour PM, Liotta DC, Geisler V, Menaldino DS, Schwartzbauer J. Inhibition of skin carcinomas but not papillomas by sphingosine, N- methylsphingosine, and N-acetylsphingosine Nutrition and Cancer. 31: 119-126. PMID 9770723 DOI: 10.1080/01635589809514690  0.72
1998 Humpf HU, Schmelz EM, Meredith FI, Vesper H, Vales TR, Wang E, Menaldino DS, Liotta DC, Merrill AH. Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase: Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor Journal of Biological Chemistry. 273: 19060-19064. PMID 9668088 DOI: 10.1074/Jbc.273.30.19060  0.72
1998 Jeffrey McAtee J, Schinazi RF, Liotta DC. A Completely Diastereoselective Electrophilic Fluorination of a Chiral, Noncarbohydrate Sugar Ring Precursor: Application to the Synthesis of Several Novel 2′-Fluoronucleosides Journal of Organic Chemistry. 63: 2161-2167.  0.72
1997 Nikolova-Karakashian M, Morgan ET, Alexander C, Liotta DC, Merrill AH. Bimodal regulation of ceramidase by interleukin-1β. Implications for the regulation of cytochrome P450 2C11 (CYP2C11) Journal of Biological Chemistry. 272: 18718-18724. PMID 9228043 DOI: 10.1074/Jbc.272.30.18718  0.72
1997 Schmelz EM, Bushnev AS, Dillehay DL, Liotta DC, Merrill AH. Suppression of aberrant colonic crypt foci by synthetic sphingomyelins with saturated or unsaturated sphingoid base backbones. Nutrition and Cancer. 28: 81-5. PMID 9200154 DOI: 10.1080/01635589709514556  0.72
1997 Goudgaon NM, El-Kattan YA, Xia X, McAtee J, Soria J, Wey SJ, Liotta DC, Schinazi RF. A general synthetic method of 5-carboranyluracil nucleosides with potential antiviral activity and use in neutron capture therapy Nucleosides and Nucleotides. 16: 2133-2150. DOI: 10.1080/07328319708002564  0.72
1997 Xia X, Wang J, Hager MW, Sisti N, Liotta DC. Stereocontrolled synthesis of β-2'-deoxypyrimidine nucleosides via intramolecular glycosylations Tetrahedron Letters. 38: 1111-1114. DOI: 10.1016/S0040-4039(96)02520-8  0.72
1996 Merrill AH, Liotta DC, Riley RT. Fumonisins: fungal toxins that shed light on sphingolipid function. Trends in Cell Biology. 6: 218-23. PMID 15157459 DOI: 10.1016/0962-8924(96)10021-0  0.72
1996 Merrill AH, Wang E, Vales TR, Smith ER, Schroeder JJ, Menaldino DS, Alexander C, Crane HM, Xia J, Liotta DC, Meredith FI, Riley RT. Fumonisin toxicity and sphingolipid biosynthesis. Advances in Experimental Medicine and Biology. 392: 297-306. PMID 8850625 DOI: 10.1007/978-1-4899-1379-1_25  0.72
1996 Merrill AH, Liotta DC, Riley RT. Sphingolipids as regulators of cellular growth, differentiation, and behavior Advances in Lipobiology. 1: 273-298. DOI: 10.1016/S1874-5245(96)80012-7  0.72
1996 Captain LF, Xia X, Liotta DC. Remote asymmetric induction in organocopper conjugate additions to 3-ketoacrylates Tetrahedron Letters. 37: 4293-4296. DOI: 10.1016/0040-4039(96)00828-3  0.72
1996 Alexander CW, Liotta DC. A diastereoselective synthesis of (2S, 3R, 4S)2-amino-1-cyclohexyl-6-methylheptane-3,4-diol, the Abbott aminodiol Tetrahedron Letters. 37: 1961-1964. DOI: 10.1016/0040-4039(96)00180-3  0.72
1995 Xie H, Voronkov M, Liotta DC, Korba BA, Schinazi RF, Richman DD, Hostetler KY. Phosphatidyl-2',3'-dideoxy-3'-thiacytidine: synthesis and antiviral activity in hepatitis B-and HIV-1-infected cells. Antiviral Research. 28: 113-20. PMID 8585765 DOI: 10.1016/0166-3542(95)00042-K  0.72
1995 Wilson LJ, Hager MW, El-Kattan YA, Liotta DC. Nitrogen glycosylation reactions involving pyrimidine and purine nucleoside bases with furanoside sugars Synthesis. 1465-1479. DOI: 10.1055/S-1995-4142  0.72
1995 Choi WB, Churchill HRO, Lynch JE, Volante RP, Reider PJ, Shinkai I, Jones DK, Liotta DC. An unusual stereoselective decarboxylation: A key reaction to an important intermediate for carbapenem antibiotics Journal of Organic Chemistry. 60: 8367-8370. DOI: 10.1021/Jo00131A010  0.72
1994 Schinazi RF, Goudgaon NM, Fulcrand G, el Kattan Y, Lesnikowski Z, Ullas G, Moravek J, Liotta DC. Cellular pharmacology and biological activity of 5-carboranyl-2'-deoxyuridine. International Journal of Radiation Oncology, Biology, Physics. 28: 1113-20. PMID 8175396 DOI: 10.1016/0360-3016(94)90485-5  0.72
1994 Abobo CV, Ni L, Schinazi RF, Liotta DC, Boudinot FD. Pharmacokinetics of 2',3'-dideoxy-5-fluoro-3'-thiacytidine in rats. Journal of Pharmaceutical Sciences. 83: 96-9. PMID 8138919 DOI: 10.1002/Jps.2600830122  0.72
1994 Jarugula VR, Schinazi RF, Fulcrand G, el Kattan Y, Liotta DC, Boudinot FD. Pharmacokinetics of 5-carboranyl-2'-deoxyuridine in rats. Journal of Pharmaceutical Sciences. 83: 1697-9. PMID 7891296 DOI: 10.1002/Jps.2600831210  0.72
1994 Schinazi RF, Gosselin G, Faraj A, Korba BE, Liotta DC, Chu CK, Mathé C, Imbach JL, Sommadossi JP. Pure nucleoside enantiomers of beta-2',3'-dideoxycytidine analogs are selective inhibitors of hepatitis B virus in vitro. Antimicrobial Agents and Chemotherapy. 38: 2172-4. PMID 7811039 DOI: 10.1128/Aac.38.9.2172  0.72
1994 Hoekstra WJ, Press JB, Bonner MP, Andrade-Gordon P, Keane PM, Durkin KA, Liotta DC, Mayo KH. Adamantane and Nipecotic Acid Derivatives as Novel β-Turn Mimics Bioorganic and Medicinal Chemistry Letters. 4: 1361-1364. DOI: 10.1016/S0960-894X(01)80362-0  0.72
1994 Lagu BR, Liotta DC. Diastereoselective synthesis of the key lactone intermediate for the preparation of hydroxyethylene dipeptide isosteres Tetrahedron Letters. 35: 547-550. DOI: 10.1016/S0040-4039(00)75834-5  0.72
1994 Lagu BR, Liotta DC. Surprisingly high diastereoselection in the aldol reactions of sodium enolates of α-amino methyl ketones Tetrahedron Letters. 35: 4485-4488. DOI: 10.1016/S0040-4039(00)60707-4  0.72
1994 Goh JB, Lagu BR, Wurster J, Liotta DC. Aldol reactions of α-(N,N-dibenzylamino) ethyl ketones Tetrahedron Letters. 35: 6029-6032. DOI: 10.1016/0040-4039(94)88066-2  0.72
1994 Jones DK, Liotta DC, Choi WB, Volante RP, Reider PJ, Shinkai I, Churchill HRO, Lynch JE. A facially-selective protonation controls the stereochemistry of a key intermediate in the synthesis of 1β-methylcarbapenems Journal of Organic Chemistry. 59: 3749-3751.  0.72
1993 Shewach DS, Liotta DC, Schinazi RF. Affinity of the antiviral enantiomers of oxathiolane cytosine nucleosides for human 2'-deoxycytidine kinase. Biochemical Pharmacology. 45: 1540-3. PMID 8385948 DOI: 10.1016/0006-2952(93)90058-5  0.72
1993 Frick LW, St John L, Taylor LC, Painter GR, Furman PA, Liotta DC, Furfine ES, Nelson DJ. Pharmacokinetics, oral bioavailability, and metabolic disposition in rats of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, a nucleoside analog active against human immunodeficiency virus and hepatitis B virus. Antimicrobial Agents and Chemotherapy. 37: 2285-92. PMID 8285607 DOI: 10.1128/Aac.37.11.2285  0.72
1993 Wilson JE, Martin JL, Borroto-Esoda K, Hopkins S, Painter G, Liotta DC, Furman PA. The 5'-triphosphates of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolane-5-yl]cytosine equally inhibit human immunodeficiency virus type 1 reverse transcriptase. Antimicrobial Agents and Chemotherapy. 37: 1720-2. PMID 7692813  0.72
1993 Schinazi RF, Lloyd RM, Nguyen MH, Cannon DL, McMillan A, Ilksoy N, Chu CK, Liotta DC, Bazmi HZ, Mellors JW. Characterization of human immunodeficiency viruses resistant to oxathiolane-cytosine nucleosides. Antimicrobial Agents and Chemotherapy. 37: 875-81. PMID 7684216 DOI: 10.1128/Aac.37.4.875  0.72
1993 Mathez D, Schinazi RF, Liotta DC, Leibowitch J. Infectious amplification of wild-type human immunodeficiency virus from patients' lymphocytes and modulation by reverse transcriptase inhibitors in vitro. Antimicrobial Agents and Chemotherapy. 37: 2206-11. PMID 7504908  0.72
1993 Sperka J, Liotta DC. Onium ions are not on the reaction coordinate in the formation of heterocycles via electrophile-induced alkenol cyclizations Heterocycles. 35: 701-706. DOI: 10.3987/Com-92-S(T)134  0.72
1993 Van Roey P, Pangborn WA, Schinazi RF, Painter G, Liotta DC. Absolute configuration of the antiviral agent (-)-cis-5-fluoro-1-[2-hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine Antiviral Chemistry and Chemotherapy. 4: 369-375. DOI: 10.1177/095632029300400609  0.72
1993 Lagu BR, Crane HM, Liotta DC. Highly diastereoselective aldol reactions of chiral methyl ketones Journal of Organic Chemistry. 58: 4191-4193. DOI: 10.1021/Jo00068A006  0.72
1993 Jones DK, Liotta DC, Shinkai I, Mathre DJ. Origins of the enantioselectivity observed in oxazaborolidine-catalyzed reductions of ketones Journal of Organic Chemistry. 58: 799-801. DOI: 10.1021/Jo00056A001  0.72
1993 Choi WB, Yeola S, Liotta DC, Schinazi RF, Painter GR, Davis M, St. Clair M, Furman PA. Synthesis, anti-human immunodeficiency virus, and anti-hepatitis B virus activity of pyrimidine oxathiolane nucleosides Bioorganic and Medicinal Chemistry Letters. 3: 693-696. DOI: 10.1016/S0960-894X(01)81256-7  0.72
1993 Wilson LJ, Choi WB, Spurling T, Liotta DC, Schinazi RF, Cannon D, Painter GR, St. Clair M, Furman PA. The synthesis and anti-hiv activity of pyrimidine dioxolanyl nucleosides Bioorganic and Medicinal Chemistry Letters. 3: 169-174. DOI: 10.1016/S0960-894X(01)80870-2  0.72
1993 Jones DK, Liotta DC. Episulfonium ions may not be the stereodeterminants in glycosylations of 2-thioalkyl pyranosides Tetrahedron Letters. 34: 7209-7212. DOI: 10.1016/S0040-4039(00)79289-6  0.72
1993 Wang J, Wurster JA, Wilson LJ, Liotta D. Stereocontrolled glycosylations via additions of sulfur electrophiles to glycals Tetrahedron Letters. 34: 4881-4884. DOI: 10.1016/S0040-4039(00)74036-6  0.72
1992 Enkvetchakul B, Barnett T, Liotta DC, Geisler V, Menaldino D, Merrill AH, Birt DF. Influences of sphingosine on two-stage skin tumorigenesis in Sencar mice. Cancer Letters. 62: 35-42. PMID 1540929 DOI: 10.1016/0304-3835(92)90195-2  0.72
1992 Schinazi RF, Boudinot FD, Ibrahim SS, Manning C, McClure HM, Liotta DC. Pharmacokinetics and metabolism of racemic 2',3'-dideoxy-5-fluoro-3'-thiacytidine in rhesus monkeys. Antimicrobial Agents and Chemotherapy. 36: 2432-8. PMID 1336946 DOI: 10.1128/Aac.36.11.2432  0.72
1992 Furman PA, Davis M, Liotta DC, Paff M, Frick LW, Nelson DJ, Dornsife RE, Wurster JA, Wilson LJ, Fyfe JA. The anti-hepatitis B virus activities, cytotoxicities, and anabolic profiles of the (-) and (+) enantiomers of cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine. Antimicrobial Agents and Chemotherapy. 36: 2686-92. PMID 1336341  0.72
1992 Swiss KA, Hinkley W, Maryanoff CA, Liotta DC. Complementary facial selectivity in conjugate additions to γ-hydroxyenones Synthesis. 127-131. DOI: 10.1055/S-1992-34179  0.72
1992 Hoong LK, Strange LE, Liotta DC, Koszalka GW, Burns CL, Schinazi RF. Enzyme-mediated enantioselective preparation of pure enantiomers of the antiviral agent 2′,3′-dideoxy-5-Fluoro-3′-Thiacytidine (FTC) and related compounds Journal of Organic Chemistry. 57: 5563-5565. DOI: 10.1021/Jo00047A004  0.72
1992 Hager MW, Liotta DC. An efficient synthesis of 3′-fluoro-3′-deoxythymidene (FLT) Tetrahedron Letters. 33: 7083-7086. DOI: 10.1016/S0040-4039(00)60841-9  0.72
1992 Wurster JA, Wilson LJ, Morin GT, Liotta D. Suppression of racemization during the diastereoselective C-3 functionalization of 5-hydroxymethyl-2-phenylthio-2-(5H)-furanones Tetrahedron Letters. 33: 5689-5692. DOI: 10.1016/0040-4039(92)89006-X  0.72
1992 Wilson LJ, Liotta DC. Diastereoselective sulfenylation reactions employing N-(phenylthio)lactams under nonbasic conditions Journal of Organic Chemistry. 57: 1948-1950.  0.72
1991 Doong SL, Tsai CH, Schinazi RF, Liotta DC, Cheng YC. Inhibition of the replication of hepatitis B virus in vitro by 2',3'-dideoxy-3'-thiacytidine and related analogues. Proceedings of the National Academy of Sciences of the United States of America. 88: 8495-9. PMID 1656445 DOI: 10.1073/Pnas.88.19.8495  0.72
1991 Hager MW, Liotta DC. Cyclization protocols for controlling the glycosidic stereochemistry of nucleosides. Application to the synthesis of the antiviral agent 3'-azido-3'-deoxythymidine (AZT) Journal of the American Chemical Society. 113: 5117-5119. DOI: 10.1021/Ja00013A088  0.72
1991 Merrill AH, Liotta DC. Lipids as hormones and second messengers Current Opinion in Structural Biology. 1: 516-521. DOI: 10.1016/S0959-440X(05)80071-5  0.72
1991 Swiss KA, Choi WB, Liotta DC, Abdel-Magid AF, Maryanoff CA. Use of the magnesium cation in aldol additions. A convenient method for achieving anti-aldol selectivity Journal of Organic Chemistry. 56: 5978-5980.  0.72
1991 Choi WB, Wilson LJ, Yeola S, Liotta DC, Schinazi RF. In situ complexation directs the stereochemistry of N-glycosylation in the synthesis of oxathiolanyl and dioxolanyl nucleoside analogues Journal of the American Chemical Society. 113: 9377-9379.  0.72
1990 Stevens VL, Nimkar S, Jamison WC, Liotta DC, Merrill AH. Characteristics of the growth inhibition and cytotoxicity of long-chain (sphingoid) bases for Chinese hamster ovary cells: evidence for an involvement of protein kinase C. Biochimica Et Biophysica Acta. 1051: 37-45. PMID 2297538 DOI: 10.1016/0167-4889(90)90171-9  0.72
1990 Greenberg P, Merrill AH, Liotta DC, Grabowski GA. Human acid beta-glucosidase: use of sphingosyl and N-alkyl-glucosylamine inhibitors to investigate the properties of the active site. Biochimica Et Biophysica Acta. 1039: 12-20. PMID 2141287 DOI: 10.1016/0167-4838(90)90220-A  0.72
1990 Wilson LJ, Liotta D. A general method for controlling glycosylation stereochemistry in the synthesis of 2′-deoxyribose nucleosides Tetrahedron Letters. 31: 1815-1818. DOI: 10.1016/S0040-4039(00)98793-8  0.72
1990 Liebeskind LS, Chidambaram R, Nimkar S, Liotta D. A synthesis of the abietane diterpenoid quinone (±)-royleanone via maleoylcobalt technology Tetrahedron Letters. 31: 3723-3726. DOI: 10.1016/S0040-4039(00)97454-9  0.72
1990 Swiss KA, Liotta DC, Maryanoff CA. Mechanistic aspects of the ligand-assisted nucleophilic addition reaction Journal of the American Chemical Society. 112: 9393-9394.  0.72
1988 Merrill AH, Wang E, Mullins RE, Jamison WC, Nimkar S, Liotta DC. Quantitation of free sphingosine in liver by high-performance liquid chromatography. Analytical Biochemistry. 171: 373-81. PMID 3407935 DOI: 10.1016/0003-2697(88)90500-3  0.72
1988 Nimkar S, Menaldino D, Merrill AH, Liotta D. A stereoselective synthesis of sphingosine, a protein kinase c inhibitor Tetrahedron Letters. 29: 3037-3040. DOI: 10.1016/0040-4039(88)85079-2  0.72
1985 Bresciani-Pahor N, Calligaris M, Randaccio L, Marzilli LG, Summers MF, Toscano PJ, Grossman J, Liotta D. The 2,2,2-trifluoroethyl ligand: A structural "reporter" group for its carbanion character in organometallic compounds Organometallics. 4: 630-636. DOI: 10.1021/Om00123A003  0.72
1985 Liotta D, Saindane M, Barnum C, Zima G. Synthetic applications of 2-phenylselenenylenones-III. An overview Tetrahedron. 41: 4881-4889. DOI: 10.1016/S0040-4020(01)96727-4  0.72
1981 Liotta D, Saindane M, Barnum C, Ensley H, Balakrishnan P. Reactions involving selenium metal as an electrophile. 2. A general procedure for the preparation of unsaturated β-dicarbonyl compounds Tetrahedron Letters. 22: 3043-3046. DOI: 10.1016/S0040-4039(01)81822-0  0.72
1980 Liotta D, Zima G, Barnum C, Saindane M. Reactions involving selenium metal as an electrophile. The enolate - selenolate transformation Tetrahedron Letters. 21: 3643-3646. DOI: 10.1016/S0040-4039(00)78733-8  0.72
1978 Baker AD, Brisk MA, Liotta DC. ELECTRON SPECTROSCOPY: ULTRAVIOLET AND X-RAY EXCITATION Analytical Chemistry. 50: 328R-346R. DOI: 10.1021/Ac50055A021  0.72
1978 Baker AD, Wong D, Lo S, Bloch M, Horozoglu G, Goldman NL, Engel R, Liotta DC. The reaction of N-aryl nitrones with dichloroketene: A new synthesis of isatins Tetrahedron Letters. 19: 219-222. DOI: 10.1016/S0040-4039(01)85088-7  0.72
1976 Baker AD, Brisk MA, Venanzi TJ, Kwon YS, Sadka S, Liotta DC. Spiroconjugation involving sulfur 3p atomic orbitals Tetrahedron Letters. 17: 3415-3418. DOI: 10.1016/S0040-4039(00)93059-4  0.72
1976 Paquette LA, Liotta DC, Baker AD. Frontier molecular orbital basis for the structurally dependent regiospecific reactions of singlet (1Δg) oxygen with polyolefins Tetrahedron Letters. 17: 2681-2684. DOI: 10.1016/S0040-4039(00)77794-X  0.72
1976 Paquette LA, Liao CC, Liotta DC, Fristad WE. Reversal of stereospecificity during allylic hydroperoxidation of 3-norcarene and bicyclo[4.2.0]oct-3-ene derivatives arising from structurally enforced quenching of singlet oxygen by the hydrazide functionality [21] Journal of the American Chemical Society. 98: 6412-6413.  0.72
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