Alan Frazer, Ph.D. - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
pharmacology

182 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Frazer A. Neuropsychopharmacology: Reflections on 40 Volumes. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 2853-5. PMID 26548764 DOI: 10.1038/Npp.2015.290  1
2015 Katz MM, Berman N, Bowden CL, Frazer A. Evidence for shortening the duration of clinical trials of antidepressants and a proposed paradigm for such studies. Journal of Clinical Psychopharmacology. 35: 329-32. PMID 25874919 DOI: 10.1097/Jcp.0000000000000317  1
2015 Benmansour S, Adeniji OS, Privratsky AA, Frazer A. Effects of Long-Term Treatment with Estradiol and Estrogenreceptor Subtype Agonists on Serotonergic Function in Ovariectomized Rats Neuroendocrinology. DOI: 10.1159/000437268  1
2014 Shah A, Carreno FR, Frazer A. Therapeutic modalities for treatment resistant depression: focus on vagal nerve stimulation and ketamine. Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology. 12: 83-93. PMID 25191499 DOI: 10.9758/Cpn.2014.12.2.83  1
2014 Perez SM, Carreno FR, Frazer A, Lodge DJ. Vagal nerve stimulation reverses aberrant dopamine system function in the methylazoxymethanol acetate rodent model of schizophrenia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 9261-7. PMID 25009259 DOI: 10.1523/Jneurosci.0588-14.2014  1
2014 Shah A, Frazer A. Influence of acute or chronic administration of ovarian hormones on the effects of desipramine in the forced swim test in female rats. Psychopharmacology. 231: 3685-94. PMID 24590054 DOI: 10.1007/S00213-014-3510-9  1
2014 Benmansour S, Privratsky AA, Adeniji OS, Frazer A. Signaling mechanisms involved in the acute effects of estradiol on 5-HT clearance. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 765-77. PMID 24423185 DOI: 10.1017/S146114571300165X  1
2014 Carreno FR, Frazer A. Activation of signaling pathways downstream of the brain-derived neurotrophic factor receptor, TrkB, in the rat brain by vagal nerve stimulation and antidepressant drugs. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 247-58. PMID 24103847 DOI: 10.1017/S1461145713000977  1
2014 Frazer A, Grace A. Editorial International Journal of Neuropsychopharmacology. DOI: 10.1017/S1461145714001059  1
2014 Frazer A. Announcements International Journal of Neuropsychopharmacology. 17: 187. DOI: 10.1017/S1461145713001491  1
2013 Frazer A, Artigas F. Preclinical models of schizophrenia. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 2129. PMID 24369034 DOI: 10.1017/S1461145713001181  1
2013 Bingham BC, Sheela Rani CS, Frazer A, Strong R, Morilak DA. Exogenous prenatal corticosterone exposure mimics the effects of prenatal stress on adult brain stress response systems and fear extinction behavior. Psychoneuroendocrinology. 38: 2746-57. PMID 23937971 DOI: 10.1016/J.Psyneuen.2013.07.003  1
2012 Roth MK, Bingham B, Shah A, Joshi A, Frazer A, Strong R, Morilak DA. Effects of chronic plus acute prolonged stress on measures of coping style, anxiety, and evoked HPA-axis reactivity. Neuropharmacology. 63: 1118-26. PMID 22842072 DOI: 10.1016/J.Neuropharm.2012.07.034  1
2012 Furmaga H, Carreno FR, Frazer A. Vagal nerve stimulation rapidly activates brain-derived neurotrophic factor receptor TrkB in rat brain. Plos One. 7: e34844. PMID 22563458 DOI: 10.1371/Journal.Pone.0034844  1
2012 Furmaga H, Sadhu M, Frazer A. Comparison of ΔFosB immunoreactivity induced by vagal nerve stimulation with that caused by pharmacologically diverse antidepressants. The Journal of Pharmacology and Experimental Therapeutics. 341: 317-25. PMID 22286499 DOI: 10.1124/Jpet.111.188953  1
2012 Benmansour S, Weaver RS, Barton AK, Adeniji OS, Frazer A. Comparison of the effects of estradiol and progesterone on serotonergic function. Biological Psychiatry. 71: 633-41. PMID 22225849 DOI: 10.1016/J.Biopsych.2011.11.023  1
2012 Frazer A. Eating disorders and obesity International Journal of Neuropsychopharmacology. 15: 147. DOI: 10.1017/S1461145712000089  1
2011 Furmaga H, Shah A, Frazer A. Serotonergic and noradrenergic pathways are required for the anxiolytic-like and antidepressant-like behavioral effects of repeated vagal nerve stimulation in rats. Biological Psychiatry. 70: 937-45. PMID 21907323 DOI: 10.1016/J.Biopsych.2011.07.020  1
2011 Green MK, Rani CS, Joshi A, Soto-Piña AE, Martinez PA, Frazer A, Strong R, Morilak DA. Prenatal stress induces long term stress vulnerability, compromising stress response systems in the brain and impairing extinction of conditioned fear after adult stress. Neuroscience. 192: 438-51. PMID 21723377 DOI: 10.1016/J.Neuroscience.2011.06.041  1
2011 Katz MM, Berman N, Bowden CL, Frazer A. The componential approach enhances the effectiveness of 2-week trials for new antidepressants. Journal of Clinical Psychopharmacology. 31: 253-4. PMID 21364343 DOI: 10.1097/Jcp.0B013E3182103461  1
2010 Katz MM, Bowden CL, Frazer A. Rethinking depression and the actions of antidepressants: uncovering the links between the neural and behavioral elements. Journal of Affective Disorders. 120: 16-23. PMID 19735945 DOI: 10.1016/J.Jad.2009.08.011  1
2009 Benmansour S, Piotrowski JP, Altamirano AV, Frazer A. Impact of ovarian hormones on the modulation of the serotonin transporter by fluvoxamine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 555-64. PMID 18322468 DOI: 10.1038/Npp.2008.23  1
2008 Cunningham JT, Mifflin SW, Gould GG, Frazer A. Induction of c-Fos and DeltaFosB immunoreactivity in rat brain by Vagal nerve stimulation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1884-95. PMID 17957222 DOI: 10.1038/Sj.Npp.1301570  1
2008 Bondi CO, Rodriguez G, Gould GG, Frazer A, Morilak DA. Chronic unpredictable stress induces a cognitive deficit and anxiety-like behavior in rats that is prevented by chronic antidepressant drug treatment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 320-31. PMID 17406647 DOI: 10.1038/Sj.Npp.1301410  1
2007 Gould GG, Brooks BW, Frazer A. [(3)H] citalopram binding to serotonin transporter sites in minnow brains. Basic & Clinical Pharmacology & Toxicology. 101: 203-10. PMID 17697042 DOI: 10.1111/J.1742-7843.2007.00100.X  1
2007 Price DA, Owens WA, Gould GG, Frazer A, Roberts JL, Daws LC, Giuffrida A. CB1-independent inhibition of dopamine transporter activity by cannabinoids in mouse dorsal striatum. Journal of Neurochemistry. 101: 389-96. PMID 17250681 DOI: 10.1111/J.1471-4159.2006.04383.X  1
2007 Gould GG, Javors MA, Frazer A. Effect of chronic administration of duloxetine on serotonin and norepinephrine transporter binding sites in rat brain. Biological Psychiatry. 61: 210-5. PMID 16650830 DOI: 10.1016/J.Biopsych.2006.02.029  1
2007 Ordway GA, Schwartz MA, Frazer A. Brain norepinephrine: Neurobiology and therapeutics Brain Norepinephrine: Neurobiology and Therapeutics. 1-642. DOI: 10.1017/CBO9780511544156  1
2006 Katz MM, Bowden CL, Berman N, Frazer A. Resolving the onset of antidepressants' clinical actions: critical for clinical practice and new drug development. Journal of Clinical Psychopharmacology. 26: 549-53. PMID 17110809 DOI: 10.1097/01.Jcp.0000246220.04422.De  1
2006 Katz MM, Frazer A, Bowden CL. 'Delay' hypothesis of onset of antidepressant action. The British Journal of Psychiatry : the Journal of Mental Science. 188: 586; author reply 58. PMID 16738353 DOI: 10.1192/Bjp.188.6.586-A  1
2006 Nemeroff CB, Mayberg HS, Krahl SE, McNamara J, Frazer A, Henry TR, George MS, Charney DS, Brannan SK. VNS therapy in treatment-resistant depression: clinical evidence and putative neurobiological mechanisms. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1345-55. PMID 16641939 DOI: 10.1038/Sj.Npp.1301082  1
2006 Gould GG, Altamirano AV, Javors MA, Frazer A. A comparison of the chronic treatment effects of venlafaxine and other antidepressants on serotonin and norepinephrine transporters. Biological Psychiatry. 59: 408-14. PMID 16140280 DOI: 10.1016/J.Biopsych.2005.07.011  1
2006 Katz MM, Houston JP, Brannan S, Tekell J, Berman N, Bowden CL, Frazer A. A video method for the evaluation of antidepressant clinical and behavioural actions. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 9: 327-36. PMID 16035957 DOI: 10.1017/S1461145705005778  1
2005 Frazer A, Morilak DA. What should animal models of depression model? Neuroscience and Biobehavioral Reviews. 29: 515-23. PMID 15893377 DOI: 10.1016/J.Neubiorev.2005.03.006  1
2005 Daws LC, Montañez S, Owens WA, Gould GG, Frazer A, Toney GM, Gerhardt GA. Transport mechanisms governing serotonin clearance in vivo revealed by high-speed chronoamperometry. Journal of Neuroscience Methods. 143: 49-62. PMID 15763136 DOI: 10.1016/J.Jneumeth.2004.09.011  1
2004 Katz MM, Houston JP, Brannan S, Bowden CL, Berman N, Swann AC, Frazer A. A multivantaged behavioural method for measuring onset and sequence of the clinical actions of antidepressants. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 7: 471-9. PMID 15154974 DOI: 10.1017/S1461145704004407  1
2004 Morilak DA, Frazer A. Antidepressants and brain monoaminergic systems: a dimensional approach to understanding their behavioural effects in depression and anxiety disorders. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 7: 193-218. PMID 15003145 DOI: 10.1017/S1461145704004080  1
2004 Benmansour S, Altamirano AV, Jones DJ, Sanchez TA, Gould GG, Pardon MC, Morilak DA, Frazer A. Regulation of the norepinephrine transporter by chronic administration of antidepressants. Biological Psychiatry. 55: 313-6. PMID 14744474 DOI: 10.1016/S0006-3223(03)00676-0  1
2004 Katz MM, Tekell JL, Bowden CL, Brannan S, Houston JP, Berman N, Frazer A. Onset and early behavioral effects of pharmacologically different antidepressants and placebo in depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 566-79. PMID 14627997 DOI: 10.1038/Sj.Npp.1300341  1
2004 Frazer A, Katz MM. Mechanisms of antidepressant action: Is onset early or late? Drug Discovery Today: Disease Mechanisms. 1: 429-433. DOI: 10.1016/J.Ddmec.2004.11.019  1
2003 Montañez S, Daws LC, Gould GG, Frazer A. Serotonin (5-HT) transporter (SERT) function after graded destruction of serotonergic neurons. Journal of Neurochemistry. 87: 861-7. PMID 14622117 DOI: 10.1046/J.1471-4159.2003.02032.X  1
2003 Gould GG, Mehta AK, Frazer A, Ticku MK. Quantitative autoradiographic analysis of the new radioligand [(3)H](2E)-(5-hydroxy-5,7,8,9-tetrahydro-6H-benzo[a][7]annulen-6-ylidene) ethanoic acid ([(3)H]NCS-382) at gamma-hydroxybutyric acid (GHB) binding sites in rat brain. Brain Research. 979: 51-6. PMID 12850570 DOI: 10.1016/S0006-8993(03)02865-8  1
2003 Gould GG, Pardon MC, Morilak DA, Frazer A. Regulatory effects of reboxetine treatment alone, or following paroxetine treatment, on brain noradrenergic and serotonergic systems. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1633-41. PMID 12825093 DOI: 10.1038/Sj.Npp.1300236  1
2003 Galici R, Galli A, Jones DJ, Sanchez TA, Saunders C, Frazer A, Gould GG, Lin RZ, France CP. Selective decreases in amphetamine self-administration and regulation of dopamine transporter function in diabetic rats. Neuroendocrinology. 77: 132-40. PMID 12624535 DOI: 10.1159/000068650  1
2002 Montañez S, Daws LC, Gould GG, Gerhardt GA, Frazer A. Differential in vivo clearance of serotonin in rat dorsal raphe nucleus and CA3 region. Brain Research. 955: 236-44. PMID 12419542 DOI: 10.1016/S0006-8993(02)03470-4  1
2002 Katz MM, Halbreich UM, Bowden CL, Frazer A, Pinder RM, Rush AJ, Wheatley DP, Lebowitz BD. Enhancing the technology of clinical trials and the trials model to evaluate newly developed, targeted antidepressants. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 319-28. PMID 12225690 DOI: 10.1016/S0893-133X(02)00329-9  1
2002 Benmansour S, Owens WA, Cecchi M, Morilak DA, Frazer A. Serotonin clearance in vivo is altered to a greater extent by antidepressant-induced downregulation of the serotonin transporter than by acute blockade of this transporter. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6766-72. PMID 12151556 DOI: 10.1523/Jneurosci.22-15-06766.2002  1
2002 Frazer A, Benmansour S. Delayed pharmacological effects of antidepressants. Molecular Psychiatry. 7: S23-8. PMID 11986992 DOI: 10.1038/Sj.Mp.4001015  1
2001 Clarke WP, Berg KA, Gould G, Frazer A. Characterization of 5-HT(₁A,B) and 5-HT(â‚‚A,C) serotonin receptor binding. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. Unit1.23. PMID 21959751 DOI: 10.1002/0471141755.Ph0123S12  1
2001 Frazer A. Serotonergic and noradrenergic reuptake inhibitors: prediction of clinical effects from in vitro potencies. The Journal of Clinical Psychiatry. 62: 16-23. PMID 11430614  1
2000 Javors MA, Houston JP, Tekell JL, Brannan SK, Frazer A. Reduction of platelet serotonin content in depressed patients treated with either paroxetine or desipramine. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 3: 229-235. PMID 11343600 DOI: 10.1017/S146114570000198X  1
2000 Daws LC, Gould GG, Teicher SD, Gerhardt GA, Frazer A. 5-HT(1B) receptor-mediated regulation of serotonin clearance in rat hippocampus in vivo. Journal of Neurochemistry. 75: 2113-22. PMID 11032901 DOI: 10.1046/J.1471-4159.2000.0752113.X  1
2000 Frazer A. Norepinephrine involvement in antidepressant action. The Journal of Clinical Psychiatry. 61: 25-30. PMID 10910014  1
1999 Frazer A, Gerhardt GA, Daws LC. New views of biogenic amine transporter function: implications for neuropsychopharmacology. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 2: 305-320. PMID 11285147 DOI: 10.1017/S1461145799001625  1
1999 Benmansour S, Cecchi M, Morilak DA, Gerhardt GA, Javors MA, Gould GG, Frazer A. Effects of chronic antidepressant treatments on serotonin transporter function, density, and mRNA level. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 10494-501. PMID 10575045 DOI: 10.1523/Jneurosci.19-23-10494.1999  1
1999 Daws LC, Gerhardt GA, Frazer A. 5-HT1B antagonists modulate clearance of extracellular serotonin in rat hippocampus. Neuroscience Letters. 266: 165-8. PMID 10465699 DOI: 10.1016/S0304-3940(99)00277-3  1
1998 Frazer A, Daws LC. Serotonin transporter function in vivo: assessment by chronoamperometry. Annals of the New York Academy of Sciences. 861: 217-29. PMID 9928259 DOI: 10.1111/J.1749-6632.1998.Tb10193.X  1
1998 Daws LC, Lopez R, Frazer A. Effects of antidepressant treatment on inhibitory avoidance behavior and amygdaloid beta-adrenoceptors in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 19: 300-13. PMID 9718593 DOI: 10.1016/S0893-133X(98)00016-5  1
1998 Daws LC, Toney GM, Gerhardt GA, Frazer A. In vivo chronoamperometric measures of extracellular serotonin clearance in rat dorsal hippocampus: contribution of serotonin and norepinephrine transporters. The Journal of Pharmacology and Experimental Therapeutics. 286: 967-76. PMID 9694957  1
1997 Schweizer E, Thielen RJ, Frazer A. Venlafaxine:a novel antidepressant compound. Expert Opinion On Investigational Drugs. 6: 65-78. PMID 15989562 DOI: 10.1517/13543784.6.1.65  1
1997 Daws LC, Toney GM, Davis DJ, Gerhardt GA, Frazer A. In vivo chronoamperometric measurements of the clearance of exogenously applied serotonin in the rat dentate gyrus. Journal of Neuroscience Methods. 78: 139-50. PMID 9497010 DOI: 10.1016/S0165-0270(97)00144-1  1
1997 Katz MM, Bowden C, Stokes P, Casper R, Frazer A, Koslow SH, Kocsis J, Secunda S, Swann A, Berman N. Can the effects of antidepressants be observed in the first two weeks of treatment? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 17: 110-5. PMID 9252986 DOI: 10.1016/S0893-133X(97)00038-9  1
1997 Frazer A. Antidepressants. The Journal of Clinical Psychiatry. 58: 9-25. PMID 9227669  1
1997 Frazer A. Pharmacology of antidepressants. Journal of Clinical Psychopharmacology. 17: 2S-18S. PMID 9090573 DOI: 10.1097/00004714-199704001-00002  1
1996 Katz MM, Koslow SH, Frazer A. Onset of antidepressant activity: reexamining the structure of depression and multiple actions of drugs. Depression and Anxiety. 4: 257-67. PMID 9166653 DOI: 10.1002/(Sici)1520-6394(1996)4:6<257::Aid-Da1>3.0.Co;2-9  1
1996 Thielen RJ, Fangon NB, Frazer A. 4-(2'-Methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p-iodobenzamido]ethyl] piperazine and 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridinyl)-p- fluorobenzamido]ethyl]piperazine, two new antagonists at pre- and postsynaptic serotonin-1A receptors. The Journal of Pharmacology and Experimental Therapeutics. 277: 661-70. PMID 8627543  1
1995 Thielen RJ, Frazer A. Effects of novel 5-HT1A receptor antagonists on measures of post-synaptic 5-HT1A receptor activation in vivo. Life Sciences. 56: PL163-8. PMID 7869825 DOI: 10.1016/0024-3205(94)00486-C  1
1994 Hensler JG, Ferry RC, Labow DM, Kovachich GB, Frazer A. Quantitative autoradiography of the serotonin transporter to assess the distribution of serotonergic projections from the dorsal raphe nucleus. Synapse (New York, N.Y.). 17: 1-15. PMID 8042142 DOI: 10.1002/Syn.890170102  1
1994 Scott PA, Chou JM, Tang H, Frazer A. Differential induction of 5-HT1A-mediated responses in vivo by three chemically dissimilar 5-HT1A agonists. The Journal of Pharmacology and Experimental Therapeutics. 270: 198-208. PMID 8035316  1
1994 Katz MM, Maas JW, Frazer A, Koslow SH, Bowden CL, Berman N, Swann AC, Stokes PE. Drug-induced actions on brain neurotransmitter systems and changes in the behaviors and emotions of depressed patients. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 11: 89-100. PMID 7530963 DOI: 10.1038/Npp.1994.38  1
1993 Montgomery SA, Feighner JP, Frazer A, Magni G, Muth EA. Venlafaxine: A new dimension in antidepressant pharmacotherapy Journal of Clinical Psychiatry. 54: 119-126. PMID 8468312  1
1993 Chamberlain J, Offord SJ, Wolfe BB, Tyau LS, Wang HL, Frazer A. Potency of 5-hydroxytryptamine1a agonists to inhibit adenylyl cyclase activity is a function of affinity for the "low-affinity" state of [3H]8-hydroxy-N,N-dipropylaminotetralin ([3H]8-OH-DPAT) binding. The Journal of Pharmacology and Experimental Therapeutics. 266: 618-25. PMID 8355195  1
1993 Kovachich GB, Frazer A, Aronson CE. Effect of chronic administration of antidepressants on alpha 2-adrenoceptors in the locus coeruleus and its projection fields in rat brain determined by quantitative autoradiography. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 8: 57-65. PMID 8093834 DOI: 10.1038/Npp.1993.7  1
1992 Katz MM, Maas J, Frazer A, Koslow S. Disentangling antidepressant drug actions on anxiety and depression and the relationships to neurochemistry. Clinical Neuropharmacology. 15: 535A. PMID 1498938 DOI: 10.1097/00002826-199201001-00278  1
1992 Chumpradit S, Kung MP, Panyachotipun C, Prapansiri V, Foulon C, Brooks BP, Szabo SA, Tejani-Butt S, Frazer A, Kung HF. Iodinated tomoxetine derivatives as selective ligands for serotonin and norepinephrine uptake sites. Journal of Medicinal Chemistry. 35: 4492-7. PMID 1447750 DOI: 10.1021/Jm00101A029  1
1991 Hensler JG, Kovachich GB, Frazer A. A quantitative autoradiographic study of serotonin1A receptor regulation. Effect of 5,7-dihydroxytryptamine and antidepressant treatments. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 4: 131-44. PMID 2025379  1
1991 Katz MM, Koslow SH, Maas JW, Frazer A, Kocsis J, Secunda S, Bowden CL, Casper RC. Identifying the specific clinical actions of amitriptyline: interrelationships of behaviour, affect and plasma levels in depression. Psychological Medicine. 21: 599-611. PMID 1946849 DOI: 10.1017/S0033291700022236  1
1991 Hensler JG, Ordway GA, Gambarana C, Areso P, Frazer A. Serotonergic neurons do not influence the regulation of beta adrenoceptors induced by either desipramine or isoproterenol. The Journal of Pharmacology and Experimental Therapeutics. 256: 656-64. PMID 1847207  1
1991 Areso MP, Frazer A. Effect of repeated administration of novel stressors on central beta adrenoceptors. Journal of Neural Transmission. General Section. 86: 229-35. PMID 1685653 DOI: 10.1007/Bf01250709  1
1991 Poland RE, Frazer A. Corticosterone and prolactin response to TFMPP in rats during repeated antidepressant administration. The Journal of Pharmacy and Pharmacology. 43: 54-6. PMID 1676062 DOI: 10.1111/J.2042-7158.1991.Tb05450.X  1
1991 Ordway GA, Gambarana C, Tejani-Butt SM, Areso P, Hauptmann M, Frazer A. Preferential reduction of binding of 125I-iodopindolol to beta-1 adrenoceptors in the amygdala of rat after antidepressant treatments. The Journal of Pharmacology and Experimental Therapeutics. 257: 681-90. PMID 1674532  1
1991 Gambarana C, Ordway GA, Hauptmann M, Tejani-Butt S, Frazer A. Central administration of 1-isoproterenol in vivo induces a preferential regulation of beta 2-adrenoceptors in the central nervous system of the rat. Brain Research. 555: 141-8. PMID 1657295 DOI: 10.1016/0006-8993(91)90870-2  1
1990 Frazer A, Maayani S, Wolfe BB. Subtypes of receptors for serotonin. Annual Review of Pharmacology and Toxicology. 30: 307-48. PMID 2188571 DOI: 10.1146/Annurev.Pa.30.040190.001515  1
1990 Frazer A, Hensler JG. 5-HT1A receptors and 5-HT1A-mediated responses: effect of treatments that modify serotonergic neurotransmission. Annals of the New York Academy of Sciences. 600: 460-74; discussion 4. PMID 2174665 DOI: 10.1111/J.1749-6632.1990.Tb16902.X  1
1990 Swann AC, Berman N, Frazer A, Koslow SH, Maas JW, Pandey GN, Secunda S. Lithium distribution in mania: single-dose pharmacokinetics and sympathoadrenal function. Psychiatry Research. 32: 71-84. PMID 2112261 DOI: 10.1016/0165-1781(90)90137-T  1
1990 Tejani-Butt SM, Brunswick DJ, Frazer A. [3H]nisoxetine: a new radioligand for norepinephrine uptake sites in brain. European Journal of Pharmacology. 191: 239-43. PMID 2086242 DOI: 10.1016/0014-2999(90)94155-Q  1
1990 Frazer A, Maayani S, Schoenfeld R. ACNP satellite workshop: Subtypes of receptors for serotonin and their effectors: Preface Neuropsychopharmacology. 3: 319. PMID 1981827  1
1989 Rybakowski JK, Amsterdam JD, Dyson WL, Frazer A, Winokur A, Kurtz J. Factors contributing to erythrocyte lithium-sodium countertransport activity in lithium-treated bipolar patients. Pharmacopsychiatry. 22: 16-20. PMID 2710807 DOI: 10.1055/S-2007-1014571  1
1989 Lucki I, Ward HR, Frazer A. Effect of 1-(m-chlorophenyl)piperazine and 1-(m-trifluoromethylphenyl)piperazine on locomotor activity. The Journal of Pharmacology and Experimental Therapeutics. 249: 155-64. PMID 2709329  1
1989 Bauer MS, Poland RE, Whybrow PC, Frazer A. Pituitary-adrenal and thyroid effects on melatonin content of the rat pineal gland. Psychoneuroendocrinology. 14: 165-75. PMID 2547223 DOI: 10.1016/0306-4530(89)90014-0  1
1988 Offord SJ, Ordway GA, Frazer A. Application of [125I]iodocyanopindolol to measure 5-hydroxytryptamine1B receptors in the brain of the rat. The Journal of Pharmacology and Experimental Therapeutics. 244: 144-53. PMID 3335996  1
1988 Brunswick DJ, Frazer A, Koslow SH, Casper R, Stokes PE, Robins E, Davis JM. Insulin-induced hypoglycaemic response and release of growth hormone in depressed patients and healthy controls. Psychological Medicine. 18: 79-91. PMID 3283809 DOI: 10.1017/S0033291700001914  1
1988 Tejani-Butt SM, Hauptmann M, D'Mello A, Frazer A, Marcoccia JM, Brunswick DJ. Evaluation of mono- and dibenzoyl esters of dopamine as potential pro-drugs for dopamine in the central nervous system. Naunyn-Schmiedeberg's Archives of Pharmacology. 338: 497-503. PMID 3244391 DOI: 10.1007/Bf00179320  1
1988 Kovachich GB, Aronson CE, Brunswick DJ, Frazer A. Quantitative autoradiography of serotonin uptake sites in rat brain using [3H]cyanoimipramine. Brain Research. 454: 78-88. PMID 2970277 DOI: 10.1016/0006-8993(88)90805-0  1
1988 Ordway GA, Gambarana C, Frazer A. Quantitative autoradiography of central beta adrenoceptor subtypes: comparison of the effects of chronic treatment with desipramine or centrally administered l-isoproterenol. The Journal of Pharmacology and Experimental Therapeutics. 247: 379-89. PMID 2845059  1
1988 Ordway GA, Frazer A. Effects of prenalterol on beta adrenergic responsiveness and receptors in the cerebral cortex of the rat. Neuropharmacology. 27: 529-36. PMID 2839793 DOI: 10.1016/0028-3908(88)90136-0  1
1987 Maas JW, Koslow SH, Davis J, Katz M, Frazer A, Bowden CL, Berman N, Gibbons R, Stokes P, Landis DH. Catecholamine metabolism and disposition in healthy and depressed subjects. Archives of General Psychiatry. 44: 337-44. PMID 3566456 DOI: 10.1001/Archpsyc.1987.01800160041007  1
1987 Katz MM, Koslow SH, Maas JW, Frazer A, Bowden CL, Casper R, Croughan J, Kocsis J, Redmond E. The timing, specificity and clinical prediction of tricyclic drug effects in depression. Psychological Medicine. 17: 297-309. PMID 3299439 DOI: 10.1017/S0033291700024831  1
1987 Ordway GA, O'Donnell JM, Frazer A. Effects of clenbuterol on central beta-1 and beta-2 adrenergic receptors of the rat. The Journal of Pharmacology and Experimental Therapeutics. 241: 187-95. PMID 3033200  1
1987 Vos P, Davenport PA, Artymyshyn RP, Frazer A, Wolfe BB. Selective regulation of beta-2 adrenergic receptors by the chronic administration of the lipophilic beta adrenergic receptor agonist clenbuterol: an autoradiographic study. The Journal of Pharmacology and Experimental Therapeutics. 242: 707-12. PMID 2886650  1
1987 Swann AC, Berman N, Frazer A, Koslow SH, Secunda S. Lithium distribution in mania: plasma and red blood cell lithium, clinical state, and monoamine metabolites during lithium treatment. Psychiatry Research. 20: 1-12. PMID 2882535 DOI: 10.1016/0165-1781(87)90118-1  1
1986 Frazer A, Ordway G, O'Donnell J, Vos P, Wolfe B. Effect of repeated administration of clenbuterol on the regulation of beta-adrenoceptors in the central nervous system of the rat. Ciba Foundation Symposium. 123: 170-90. PMID 3028723  1
1985 Sills MA, Lucki I, Frazer A. Development of selective tolerance to the serotonin behavioral syndrome and suppression of locomotor activity after repeated administration of either 5-MeODMT or mCPP. Life Sciences. 36: 2463-9. PMID 4010463 DOI: 10.1016/0024-3205(85)90142-0  1
1985 Lucki I, Frazer A. Performance and extinction of lever press behavior following chronic administration of desipramine to rats. Psychopharmacology. 85: 253-9. PMID 3923511 DOI: 10.1007/Bf00428183  1
1985 Hanin I, Koslow SH, Kocsis JH, Bowden CL, Brunswick D, Frazer A, Carl J, Robins E. Cerebrospinal fluid levels of amitriptyline, nortriptyline, imipramine and desmethylimipramine. Relationship to plasma levels and treatment outcome. Journal of Affective Disorders. 9: 69-78. PMID 3160750 DOI: 10.1016/0165-0327(85)90012-6  1
1985 O'Donnell JM, Frazer A. Effects of clenbuterol and antidepressant drugs on beta adrenergic receptor/N-protein coupling in the cerebral cortex of the rat. The Journal of Pharmacology and Experimental Therapeutics. 234: 30-6. PMID 2989510  0.92
1985 Frazer A, Lucki I, Sills M. Alterations in monoamine-containing neuronal function due to administration of antidepressants repeatedly to rats. Acta Pharmacologica Et Toxicologica. 56: 21-34. PMID 2984890 DOI: 10.1111/J.1600-0773.1985.Tb02496.X  1
1984 Sills MA, Wolfe BB, Frazer A. Multiple states of the 5-hydroxytryptamine1 receptor as indicated by the effects of GTP on [3H]5-hydroxytryptamine binding in rat frontal cortex. Molecular Pharmacology. 26: 10-8. PMID 6749126  1
1984 Lucki I, Nobler MS, Frazer A. Differential actions of serotonin antagonists on two behavioral models of serotonin receptor activation in the rat. The Journal of Pharmacology and Experimental Therapeutics. 228: 133-9. PMID 6694097  1
1984 Egeland JA, Kidd JR, Frazer A, Kidd KK, Neuhauser VI. Amish study, V: Lithium-sodium countertransport and catechol O-methyltransferase in pedigrees of bipolar probands. The American Journal of Psychiatry. 141: 1049-54. PMID 6589966 DOI: 10.1176/Ajp.141.9.1049  1
1984 Sills MA, Wolfe BB, Frazer A. Determination of selective and nonselective compounds for the 5-HT 1A and 5-HT 1B receptor subtypes in rat frontal cortex. The Journal of Pharmacology and Experimental Therapeutics. 231: 480-7. PMID 6502510  1
1984 O'Donnell JM, Wolfe BB, Frazer A. Agonist interactions with beta adrenergic receptors in rat brain. The Journal of Pharmacology and Experimental Therapeutics. 228: 640-7. PMID 6142940  1
1983 Heydorn WE, Lucki I, Frazer A. Continuous light paradoxically reduces catecholamine-induced melatonin production. Brain Research. 267: 175-8. PMID 6860943 DOI: 10.1016/0006-8993(83)91054-5  1
1983 Gerber JC, Choki J, Brunswick DJ, Reivich M, Frazer A. The effect of antidepressant drugs on regional cerebral glucose utilization in the rat. Brain Research. 269: 319-25. PMID 6309323 DOI: 10.1016/0006-8993(83)90142-7  1
1983 Frazer A, Lucki I. Is the“new” more useful than the“old”? Behavioral and Brain Sciences. 6: 554-555. DOI: 10.1017/S0140525X00017404  1
1982 Lucki I, Frazer A. Prevention of the serotonin syndrome in rats by repeated administration of monoamine oxidase inhibitors but not tricyclic antidepressants. Psychopharmacology. 77: 205-11. PMID 6812141 DOI: 10.1007/Bf00464567  1
1982 Heydorn WE, Brunswick DJ, Frazer A. Effect of treatment of rats with antidepressants on melatonin concentrations in the pineal gland and serum. The Journal of Pharmacology and Experimental Therapeutics. 222: 534-43. PMID 6286922  1
1982 Frazer A, Lucki I. Antidepressant drugs: effects on beta-adrenergic and serotonineregic receptors. Advances in Biochemical Psychopharmacology. 31: 69-90. PMID 6282067  1
1982 Weiss B, Heydorn W, Frazer A. Modulation of the beta-adrenergic receptor-adenylate cyclase system following acute and repeated treatment with antidepressants. Advances in Biochemical Psychopharmacology. 31: 37-53. PMID 6282063  1
1981 Heydorn WE, Frazer A, Weiss B. Electrical stimulation of sympathetic nerves increases the concentration of cyclic AMP in rat pineal gland. Proceedings of the National Academy of Sciences of the United States of America. 78: 7176-9. PMID 6273917 DOI: 10.1073/Pnas.78.11.7176  1
1981 Moyer JA, Greenberg LH, Frazer A, Weiss B. Subsensitivity of the beta-adrenergic receptor-linked adenylate cyclase system of rat pineal gland following repeated treatment with desmethylimipramine and nialamide. Molecular Pharmacology. 19: 187-93. PMID 6262613  1
1980 Savage DD, Mendels J, Frazer A. Decrease in [3H]-serotonin binding in rat brain produced by the repeated administration of either monoamine oxidase inhibitors or centrally acting serotonin agonists. Neuropharmacology. 19: 1063-70. PMID 7442938 DOI: 10.1016/0028-3908(80)90102-1  0.52
1980 Gengo F, Timko J, D'Antonio J, Ramsey TA, Frazer A, Mendels J. Prediction of dosage of lithium carbonate: use of a standard predictive method. The Journal of Clinical Psychiatry. 41: 319-20. PMID 7410327  1
1980 Gengo F, Frazer A, Ramsey TA, Mendels J. The lithium ratio as a guide to patient compliance. Comprehensive Psychiatry. 21: 276-80. PMID 7398251 DOI: 10.1016/0010-440X(80)90031-0  0.52
1980 Okpaku S, Frazer A, Mendels J. A pilot study of racial differences in erythrocyte lithium transport. The American Journal of Psychiatry. 137: 120-1. PMID 7352547 DOI: 10.1176/Ajp.137.1.120  0.52
1980 Savage DD, Mendels J, Frazer A. Monoamine oxidase inhibitors and serotonin uptake inhibitors: differential effects on [3H]serotonin binding sites in rat brain. The Journal of Pharmacology and Experimental Therapeutics. 212: 259-63. PMID 7351637  0.52
1980 Heydorn WE, Mendels J, Frazer A. Effects of darkness and of desmethylimipramine on pineal gland concentrations of adenosine 3', 5'-monophosphate. Biochemical Pharmacology. 29: 1341-6. PMID 6249312 DOI: 10.1016/0006-2952(80)90428-1  1
1980 Sellinger-Barnette MM, Mendels J, Frazer A. The effect of psychoactive drugs on beta-adrenergic receptor binding sites in rat brain. Neuropharmacology. 19: 447-54. PMID 6248811 DOI: 10.1016/0028-3908(80)90052-0  0.52
1980 Heydorn W, Frazer A, Mendels J. Do tricyclic antidepressants enhance adrenergic transmission? An update. The American Journal of Psychiatry. 137: 113-4. PMID 6243449 DOI: 10.1176/Ajp.137.1.113  1
1980 Hess ME, Reynolds KA, Frazer A, Viscusi D. Inhibitory effects of desmethylimipramine on the action of thyroxine on cardiac beta-receptors and myocardial phosphorylase. Journal of Cardiovascular Pharmacology. 2: 867-79. PMID 6160335 DOI: 10.1097/00005344-198011000-00015  1
1979 Schlesinger HR, Frazer A, Friedman R, Mendels J, Hummeler K. Lithium ion uptake associated with the stimulation of action potential ionophores of cultured human neuroblastoma cells. Life Sciences. 25: 957-67. PMID 513943 DOI: 10.1016/0024-3205(79)90501-0  0.52
1979 Maany I, Mendels J, Frazer A, Brunswick D. A study of growth hormone release in depression. Neuropsychobiology. 5: 282-9. PMID 460575 DOI: 10.1159/000117691  0.52
1979 Mendels J, Ramsey TA, Dyson WL, Frazer A. Lithium as an antidepressant. Archives of General Psychiatry. 36: 845-6. PMID 454103 DOI: 10.1001/Archpsyc.1979.01780080019004  0.52
1979 Ramsey TA, Frazer A, Mendels J. Plasma and erythrocyte cations in affective illness. Neuropsychobiology. 5: 1-10. PMID 431792 DOI: 10.1159/000117657  0.52
1979 Ramsey TA, Frazer A, Mendels J, Dyson WL. The erythrocyte lithium-plasma lithium ratio in patients with primary affective disorder. Archives of General Psychiatry. 36: 457-61. PMID 426613 DOI: 10.1001/Archpsyc.1979.01780040099011  0.52
1979 Savage DD, Frazer A, Mendels J. Differential effects of monoamine oxidase inhibitors and serotonin reuptake inhibitors on 3H-serotonin receptor binding in rat brain. European Journal of Pharmacology. 58: 87-8. PMID 315323 DOI: 10.1016/0014-2999(79)90344-3  0.52
1979 Moyer JA, Greenberg LH, Frazer A, Brunswick DJ, Mendels J, Weiss B. Opposite effects of acute and repeated administration of desmethylimipramine on adrenergic responsiveness in rat pineal gland. Life Sciences. 24: 2237-44. PMID 228145 DOI: 10.1016/0024-3205(79)90100-0  1
1978 Frazer A, Mendels J, Brunswick D, London J, Pring M, Ramsey TA, Rybakowski J. Erythrocyte concentrations of the lithium ion: clinical correlates and mechanisms of action. The American Journal of Psychiatry. 135: 1065-9. PMID 696927 DOI: 10.1176/Ajp.135.9.1065  0.52
1978 Frazer A, Mendels J, Brunswick D. Erythrocyte concentrations of the lithium ion: clinical correlates and mechanisms of accumulation [proceedings]. Psychopharmacology Bulletin. 14: 14-6. PMID 674527  0.52
1978 Rybakowski J, Frazer A, Mendels J, Ramsey TA. Erythrocyte accumulation of the lithium ion in control subjects and patients with primary affective disorder. Communications in Psychopharmacology. 2: 99-104. PMID 668304  0.52
1978 Rybakowski J, Frazer A, Mendels J. Lithium efflux from erythrocytes incubated in vitro during lithium carbonate administration. Communications in Psychopharmacology. 2: 105-12. PMID 668299  0.52
1978 Frazer A, Mendels J, Brunswick D, Ramsey TA. Transfer of sodium ions across the erythrocyte membrane in manic-depressive illness: treatment with lithium carbonate. Life Sciences. 22: 157-64. PMID 628307 DOI: 10.1016/0024-3205(78)90532-5  0.52
1978 Brunswick DJ, Frazer A, Mendels J, Ramsey TA. Red blood cell Li+ to plasma Li+ ratios. Are they related to plasma Li+ concentrations? Neuropsychobiology. 4: 121-7. PMID 619303 DOI: 10.1159/000117626  0.52
1978 Sarai K, Frazer A, Brunswick D, Mendels J. Desmethylimipramine-induced decrease in beta-adrenergic receptor binding in rat cerebral cortex. Biochemical Pharmacology. 27: 2179-81. PMID 215151 DOI: 10.1016/0006-2952(78)90293-9  0.52
1978 Frazer A, Hess ME, Mendels J, Gable B, Kunkel E, Bender A. Influence of acute and chronic treatment with desmethylimipramine on catecholamine effects in the rat. The Journal of Pharmacology and Experimental Therapeutics. 206: 311-9. PMID 210273  1
1977 Rybakowski J, Frazer A, Mendels J, Ramsey TA. Prediction of the lithium ratio in man by means of an in vitro test. Clinical Pharmacology and Therapeutics. 22: 465-9. PMID 902459 DOI: 10.1002/Cpt1977224465  0.52
1977 Stern S, Frazer A, Mendels J, Frustaci C. Distribution of the lithium ion in endocrine organs of the rat. Life Sciences. 20: 1669-74. PMID 875612 DOI: 10.1016/0024-3205(77)90341-1  0.52
1977 London JW, Burns D, Frazer A, Brunswick D, Garfinkel D, Mendels J. Computer simulation of the movement of lithium across erythrocyte membranes in vitro. Communications in Psychopharmacology. 1: 271-82. PMID 606478  0.52
1977 Frazer A, Mendels J, Brunswick D. Transfer of lithium ions across the erythrocyte membrane. Communications in Psychopharmacology. 1: 255-70. PMID 606477  0.52
1977 Frazer A, Mendels J. Use of L-DOPA in depression. Advances in Biochemical Psychopharmacology. 16: 671-5. PMID 329654  0.52
1977 Frazer A, Mendels J. Do tricyclic antidepressants enhance adrenergic transmission? The American Journal of Psychiatry. 134: 1040-2. PMID 197853 DOI: 10.1176/Ajp.134.9.1040  0.52
1976 Ramsey TA, Frazer A, Dyson WL, Mendels J. Letter: Intracellular lithium and clinical response. The British Journal of Psychiatry : the Journal of Mental Science. 128: 103-4. PMID 1252676 DOI: 10.1192/Bjp.128.1.103  0.52
1976 Mendels J, Frazer A, Baron J, Kukopulos A, Reginaldi D, Tondo L, Caliari B. Letter: Intra-erythrocyte lithium ion concentration and long-term maintenance treatment. Lancet. 1: 966. PMID 57368 DOI: 10.1016/S0140-6736(76)92748-3  0.52
1975 Mendels J, Frazer A. Reduced central serotonergic activity in mania: implications for the relationship between depression and mania. The British Journal of Psychiatry : the Journal of Mental Science. 126: 241-8. PMID 1125505 DOI: 10.1192/Bjp.126.3.241  0.52
1975 Schless AP, Frazer A, Mendels J, Pandey GN, Theodorides VJ. Genetic determinant of lithium ion metabolism. II. An in vivo study of lithium ion distribution across erythrocyte membranes. Archives of General Psychiatry. 32: 337-40. PMID 1115574 DOI: 10.1001/Archpsyc.1975.01760210071004  0.52
1975 Maany I, Frazer A, Mendels J. Apomorphine: effect on growth hormone. The Journal of Clinical Endocrinology and Metabolism. 40: 162-3. PMID 1112876 DOI: 10.1210/Jcem-40-1-162  0.52
1975 Mendels J, Stinnett JL, Burns D, Frazer A. Amine precursors and depression. Archives of General Psychiatry. 32: 22-30. PMID 1089400 DOI: 10.1001/Archpsyc.1975.01760190024002  0.52
1975 Frazer A, Haugaard ES, Mendels J, Haugaard N. Effects of intracellular lithium on epinephrine-induced accumulation of cyclic AMP in skeletal muscle. Biochemical Pharmacology. 24: 2273-7. PMID 175800 DOI: 10.1016/0006-2952(75)90266-X  0.52
1975 Haugaard ES, Frazer A, Mendels J, Haugaard N. Metabolic and electrolyte changes produced by lithium ions in the isolated rat diaphragm Biochemical Pharmacology. 24: 1187-1191. PMID 166645 DOI: 10.1016/0006-2952(75)90060-X  0.52
1974 Mendels J, Frazer A. Alterations in cell membrane activity in depression. The American Journal of Psychiatry. 131: 1240-6. PMID 4608979 DOI: 10.1176/Ajp.131.11.1240  0.52
1974 Dorus E, Pandey GN, Frazer A, Mendels J. Genetic determinant of lithium ion distribution. I. An in vitro monozygotic-dizygotic twin study. Archives of General Psychiatry. 31: 463-5. PMID 4473122 DOI: 10.1001/Archpsyc.1974.01760160019005  0.52
1974 Mendels J, Frazer A, Secunda SK, Stokes JW. A study of electrolyte and biogenic amine metabolism in manic-depressive illness. International Pharmacopsychiatry. 9: 206-17. PMID 4457496 DOI: 10.1159/000468135  1
1974 Frazer A, Pandey G, Mendels J, Neeley S, Kane M, Hess ME. The effect of tri-iodothyronine in combination with impramine on [3H]-cyclic AMP production in slices of rat cerebral cortex. Neuropharmacology. 13: 1311-40. PMID 4376223  1
1974 Wang YC, Pandey GN, Mendels J, Frazer A. Platelet adenylate cyclase responses in depression: implications for a receptor defect. Psychopharmacologia. 36: 291-300. PMID 4367922 DOI: 10.1007/Bf00422561  0.52
1974 Wang YC, Pandey GN, Mendels J, Frazer A. Effect of lithium on prostaglandin F1-stimulated adenylate cyclase activity of human platelets. Biochemical Pharmacology. 23: 845-55. PMID 4363215 DOI: 10.1016/0006-2952(74)90215-9  0.52
1974 Mendels J, Frazer A. Brain biogenic amine depletion and mood. Archives of General Psychiatry. 30: 447-51. PMID 4273761 DOI: 10.1001/Archpsyc.1974.01760100019004  0.52
1974 Frazer A, Pandey G, Mendels J, Neeley S, Kane M, Hess ME. The effect of tri-iodothyronine in combination with imipramine on [3H]-cyclic AMP production in slices of rat cerebral cortex Neuropharmacology. 13: 1131-1140. DOI: 10.1016/0028-3908(74)90063-X  1
1973 Frazer A, Pandey GN, Mendels J. Metabolism of tryptophan in depressive disease. Archives of General Psychiatry. 29: 528-35. PMID 4748313 DOI: 10.1001/Archpsyc.1973.04200040070012  0.52
1973 Mendels J, Frazer A. Intracellular lithium concentration and clinical response: towards a membrane theory of depression. Journal of Psychiatric Research. 10: 9-18. PMID 4730006 DOI: 10.1016/0022-3956(73)90005-8  0.52
1973 Frazer A, Mendels J, Secunda SK, Cochrane CM, Bianchi CP. The prediction of brain lithium concentrations from plasma or erythrocyte measures. Journal of Psychiatric Research. 10: 1-7. PMID 4730001  0.52
1973 Sugita ET, Stokes JW, Frazer A, Grof P, Mendels J, Goldstein FJ, Niebergall PJ. Lithium carbonate absorption in humans. Journal of Clinical Pharmacology. 13: 264-70. PMID 4488996 DOI: 10.1002/J.1552-4604.1973.TB00266.X  1
1973 Carroll BJ, Frazer A, Schless A, Mendels J. Cholinergic reversal of manic symptoms. Lancet. 1: 427-8. PMID 4119737 DOI: 10.1016/S0140-6736(73)90285-7  0.52
1972 Mendels J, Frazer A, Secunda SK. Intra-erythrocyte sodium and potassium in manic-depressive illness. Biological Psychiatry. 5: 165-71. PMID 5086957  0.52
1972 Mendels J, Frazer A, Fitzgerald RG, Ramsey TA, Stokes JW. Biogenic amine metabolites in cerebrospinal fluid of depressed and manic patients. Science (New York, N.Y.). 175: 1380-2. PMID 5059569 DOI: 10.1126/Science.175.4028.1380  1
1972 Frazer A, Hancock A, Mendels J, MacIntire R. Effect of lithium on catecholamine-induced responses in the isolated perfused guinea pig heart. Biological Psychiatry. 5: 79-87. PMID 5042315  0.52
1972 Frazer A, Fitzgerald RG, Mendels J. Erythrocyte cation concentrations and changes in dietary electrolyte intake. Experientia. 28: 1302-3. PMID 4638895 DOI: 10.1007/Bf01965308  0.52
1972 Frazer A, Secunda SK, Mendels J. A method for the determination of sodium, potassium, magnesium and lithium concentrations in erythrocytes. Clinica Chimica Acta; International Journal of Clinical Chemistry. 36: 499-509. PMID 4621509 DOI: 10.1016/0009-8981(72)90026-5  0.52
1972 Ramsey TA, Mendels J, Hamilton C, Frazer A. The effect of lithium carbonate on self-stimulating behavior in the rat. Life Sciences. Pt. 1: Physiology and Pharmacology. 11: 773-9. PMID 4570797 DOI: 10.1016/0024-3205(72)90211-1  0.52
1971 Mendels J, Frazer A, Secunda SK, Stokes JW. Biochemical changes in depression. Lancet. 1: 448-9. PMID 4100416 DOI: 10.1016/S0140-6736(71)92431-7  1
1969 Frazer A, Hess ME. Parasympathetic responses in hyperthyroid rats. The Journal of Pharmacology and Experimental Therapeutics. 170: 1-9. PMID 5351003  1
1969 Frazer A, Hess ME, Shanfeld J. The effects of thyroxine on rat heart adenosine 3',5'-monophosphate, phosphorylase b kinase and phosphorylase a activity. The Journal of Pharmacology and Experimental Therapeutics. 170: 10-6. PMID 4390812  1
1969 Shanfeld J, Frazer A, Hess ME. Dissociation of the increased formation of cardiac adenosine 3',5'-monophosphate from the positive inotropic effect of norepinephrine. The Journal of Pharmacology and Experimental Therapeutics. 169: 315-20. PMID 4309999  1
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