Florian Lesage - Publications

IPMC CNRS & University of Nice (France) 

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Royal P, Andres-Bilbe A, Ávalos Prado P, Verkest C, Wdziekonski B, Schaub S, Baron A, Lesage F, Gasull X, Levitz J, Sandoz G. Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK. Neuron. 101: 232-245.e6. PMID 30573346 DOI: 10.1016/j.neuron.2018.11.039  0.64
2018 Soussia IB, Choveau FS, Blin S, Kim EJ, Feliciangeli S, Chatelain FC, Kang D, Bichet D, Lesage F. Antagonistic Effect of a Cytoplasmic Domain on the Basal Activity of Polymodal Potassium Channels. Frontiers in Molecular Neuroscience. 11: 301. PMID 30233308 DOI: 10.3389/fnmol.2018.00301  0.4
2017 Bobak N, Feliciangeli S, Chen CC, Ben Soussia I, Bittner S, Pagnotta S, Ruck T, Biel M, Wahl-Schott C, Grimm C, Meuth SG, Lesage F. Recombinant tandem of pore-domains in a Weakly Inward rectifying K(+) channel 2 (TWIK2) forms active lysosomal channels. Scientific Reports. 7: 649. PMID 28381826 DOI: 10.1038/s41598-017-00640-8  0.4
2016 Christensen AH, Chatelain FC, Huttner IG, Olesen MS, Soka M, Feliciangeli S, Horvat C, Santiago CF, Vandenberg JI, Schmitt N, Olesen SP, Lesage F, Fatkin D. The two-pore domain potassium channel, TWIK-1, has a role in the regulation of heart rate and atrial size. Journal of Molecular and Cellular Cardiology. PMID 27103460 DOI: 10.1016/j.yjmcc.2016.04.006  0.64
2016 Ronjat M, Feng W, Dardevet L, Dong Y, Al Khoury S, Chatelain FC, Vialla V, Chahboun S, Lesage F, Darbon H, Pessah IN, De Waard M. In cellulo phosphorylation induces pharmacological reprogramming of maurocalcin, a cell-penetrating venom peptide. Proceedings of the National Academy of Sciences of the United States of America. PMID 27071086 DOI: 10.1073/pnas.1517342113  0.64
2016 Blin S, Ben Soussia I, Kim EJ, Brau F, Kang D, Lesage F, Bichet D. Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 27035965 DOI: 10.1073/pnas.1522748113  0.64
2015 Feliciangeli S, Chatelain FC, Bichet D, Lesage F. The family of K2P channels: salient structural and functional properties. The Journal of Physiology. 593: 2587-603. PMID 25530075 DOI: 10.1113/jphysiol.2014.287268  0.4
2015 Bichet D, Blin S, Feliciangeli S, Chatelain FC, Bobak N, Lesage F. Silent but not dumb: how cellular trafficking and pore gating modulate expression of TWIK1 and THIK2. Pflugers Archiv : European Journal of Physiology. 467: 1121-31. PMID 25339226 DOI: 10.1007/s00424-014-1631-y  0.4
2014 Pereira V, Busserolles J, Christin M, Devilliers M, Poupon L, Legha W, Alloui A, Aissouni Y, Bourinet E, Lesage F, Eschalier A, Lazdunski M, Noël J. Role of the TREK2 potassium channel in cold and warm thermosensation and in pain perception. Pain. 155: 2534-44. PMID 25239074 DOI: 10.1016/j.pain.2014.09.013  0.64
2014 Comoglio Y, Levitz J, Kienzler MA, Lesage F, Isacoff EY, Sandoz G. Phospholipase D2 specifically regulates TREK potassium channels via direct interaction and local production of phosphatidic acid. Proceedings of the National Academy of Sciences of the United States of America. 111: 13547-52. PMID 25197053 DOI: 10.1073/pnas.1407160111  0.64
2014 Blin S, Chatelain FC, Feliciangeli S, Kang D, Lesage F, Bichet D. Tandem pore domain halothane-inhibited K+ channel subunits THIK1 and THIK2 assemble and form active channels. The Journal of Biological Chemistry. 289: 28202-12. PMID 25148687 DOI: 10.1074/jbc.M114.600437  0.4
2014 Xiao Z, Cilz NI, Kurada L, Hu B, Yang C, Wada E, Combs CK, Porter JE, Lesage F, Lei S. Activation of neurotensin receptor 1 facilitates neuronal excitability and spatial learning and memory in the entorhinal cortex: beneficial actions in an Alzheimer's disease model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 7027-42. PMID 24828655 DOI: 10.1523/JNEUROSCI.0408-14.2014  0.64
2014 Rodrigues N, Bennis K, Vivier D, Pereira V, Chatelain FC, Chapuy E, Deokar H, Busserolles J, Lesage F, Eschalier A, Ducki S. Synthesis and structure-activity relationship study of substituted caffeate esters as antinociceptive agents modulating the TREK-1 channel European Journal of Medicinal Chemistry. 75: 391-402. PMID 24561669 DOI: 10.1016/j.ejmech.2014.01.049  0.64
2013 Wang W, Putra A, Schools GP, Ma B, Chen H, Kaczmarek LK, Barhanin J, Lesage F, Zhou M. The contribution of TWIK-1 channels to astrocyte K(+) current is limited by retention in intracellular compartments. Frontiers in Cellular Neuroscience. 7: 246. PMID 24368895 DOI: 10.3389/fncel.2013.00246  0.48
2013 Chatelain FC, Bichet D, Feliciangeli S, Larroque MM, Braud VM, Douguet D, Lesage F. Silencing of the tandem pore domain halothane-inhibited K+ channel 2 (THIK2) relies on combined intracellular retention and low intrinsic activity at the plasma membrane. The Journal of Biological Chemistry. 288: 35081-92. PMID 24163367 DOI: 10.1074/jbc.M113.503318  0.4
2013 Wang S, Benamer N, Zanella S, Kumar NN, Shi Y, Bévengut M, Penton D, Guyenet PG, Lesage F, Gestreau C, Barhanin J, Bayliss DA. TASK-2 channels contribute to pH sensitivity of retrotrapezoid nucleus chemoreceptor neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16033-44. PMID 24107938 DOI: 10.1523/JNEUROSCI.2451-13.2013  0.64
2013 Chatelain FC, Mazzuca M, Larroque MM, Rogemond V, Honnorat J, Lesage F. An ion channel chip for diagnosis and prognosis of autoimmune neurological disorders. Recent Patents On Cns Drug Discovery. 8: 171-9. PMID 24050250  0.56
2013 Bandulik S, Tauber P, Penton D, Schweda F, Tegtmeier I, Sterner C, Lalli E, Lesage F, Hartmann M, Barhanin J, Warth R. Severe hyperaldosteronism in neonatal Task3 potassium channel knockout mice is associated with activation of the intraadrenal renin-angiotensin system. Endocrinology. 154: 2712-22. PMID 23698720 DOI: 10.1210/en.2013-1101  0.48
2012 Tadmouri A, Kiyonaka S, Barbado M, Rousset M, Fablet K, Sawamura S, Bahembera E, Pernet-Gallay K, Arnoult C, Miki T, Sadoul K, Gory-Faure S, Lambrecht C, Lesage F, Akiyama S, et al. Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy. The Embo Journal. 31: 3730-44. PMID 22892567 DOI: 10.1038/emboj.2012.226  0.64
2012 Penton D, Bandulik S, Schweda F, Haubs S, Tauber P, Reichold M, Cong LD, El Wakil A, Budde T, Lesage F, Lalli E, Zennaro MC, Warth R, Barhanin J. Task3 potassium channel gene invalidation causes low renin and salt-sensitive arterial hypertension. Endocrinology. 153: 4740-8. PMID 22878402 DOI: 10.1210/en.2012-1527  0.64
2012 Peyronnet R, Sharif-Naeini R, Folgering JH, Arhatte M, Jodar M, El Boustany C, Gallian C, Tauc M, Duranton C, Rubera I, Lesage F, Pei Y, Peters DJ, Somlo S, Sachs F, et al. Mechanoprotection by polycystins against apoptosis is mediated through the opening of stretch-activated K(2P) channels. Cell Reports. 1: 241-50. PMID 22832196 DOI: 10.1016/j.celrep.2012.01.006  0.64
2012 Chatelain FC, Bichet D, Douguet D, Feliciangeli S, Bendahhou S, Reichold M, Warth R, Barhanin J, Lesage F. TWIK1, a unique background channel with variable ion selectivity Proceedings of the National Academy of Sciences of the United States of America. 109: 5499-5504. PMID 22431633 DOI: 10.1073/pnas.1201132109  0.64
2011 Lesage F, Barhanin J. Molecular physiology of pH-sensitive background K(2P) channels. Physiology (Bethesda, Md.). 26: 424-37. PMID 22170960 DOI: 10.1152/physiol.00029.2011  0.48
2011 Noël J, Sandoz G, Lesage F. Molecular regulations governing TREK and TRAAK channel functions. Channels (Austin, Tex.). 5: 402-9. PMID 21829087 DOI: 10.4161/chan.5.5.16469  0.64
2010 Gestreau C, Heitzmann D, Thomas J, Dubreuil V, Bandulik S, Reichold M, Bendahhou S, Pierson P, Sterner C, Peyronnet-Roux J, Benfriha C, Tegtmeier I, Ehnes H, Georgieff M, Lesage F, et al. Task2 potassium channels set central respiratory CO2 and O2 sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 107: 2325-30. PMID 20133877 DOI: 10.1073/pnas.0910059107  0.64
2010 Feliciangeli S, Tardy MP, Sandoz G, Chatelain FC, Warth R, Barhanin J, Bendahhou S, Lesage F. Potassium channel silencing by constitutive endocytosis and intracellular sequestration Journal of Biological Chemistry. 285: 4798-4805. PMID 19959478 DOI: 10.1074/jbc.M109.078535  0.64
2009 Sandoz G, Douguet D, Chatelain F, Lazdunski M, Lesage F. Extracellular acidification exerts opposite actions on TREK1 and TREK2 potassium channels via a single conserved histidine residue. Proceedings of the National Academy of Sciences of the United States of America. 106: 14628-33. PMID 19667202 DOI: 10.1073/pnas.0906267106  0.64
2009 Guyon A, Tardy MP, Rovère C, Nahon JL, Barhanin J, Lesage F. Glucose inhibition persists in hypothalamic neurons lacking tandem-pore K+ channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2528-33. PMID 19244527 DOI: 10.1523/JNEUROSCI.5764-08.2009  0.48
2008 Sandoz G, Lesage F. Protein complex analysis of native brain potassium channels by proteomics. Methods in Molecular Biology (Clifton, N.J.). 491: 113-23. PMID 18998088 DOI: 10.1007/978-1-59745-526-8_9  0.64
2008 Sandoz G, Tardy MP, Thümmler S, Feliciangeli S, Lazdunski M, Lesage F. Mtap2 is a constituent of the protein network that regulates twik-related K+ channel expression and trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 8545-52. PMID 18716213 DOI: 10.1523/JNEUROSCI.1962-08.2008  0.64
2008 Heitzmann D, Derand R, Jungbauer S, Bandulik S, Sterner C, Schweda F, El Wakil A, Lalli E, Guy N, Mengual R, Reichold M, Tegtmeier I, Bendahhou S, Gomez-Sanchez CE, Aller MI, ... ... Lesage F, et al. Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis. The Embo Journal. 27: 179-87. PMID 18034154 DOI: 10.1038/sj.emboj.7601934  0.64
2007 Feliciangeli S, Bendahhou S, Sandoz G, Gounon P, Reichold M, Warth R, Lazdunski M, Barhanin J, Lesage F. Does Sumoylation Control K2P1/TWIK1 Background K+ Channels? Cell. 130: 563-569. PMID 17693262 DOI: 10.1016/j.cell.2007.06.012  0.64
2006 Sandoz G, Thümmler S, Duprat F, Feliciangeli S, Vinh J, Escoubas P, Guy N, Lazdunski M, Lesage F. AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K+ channels into open leak channels Embo Journal. 25: 5864-5872. PMID 17110924 DOI: 10.1038/sj.emboj.7601437  0.64
2006 Zanzouri M, Lauritzen I, Duprat F, Mazzuca M, Lesage F, Lazdunski M, Patel A. Membrane potential-regulated transcription of the resting K+ conductance TASK-3 via the calcineurin pathway. The Journal of Biological Chemistry. 281: 28910-8. PMID 16864570 DOI: 10.1074/jbc.M606092200  0.56
2005 Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S. International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels. Pharmacological Reviews. 57: 527-40. PMID 16382106 DOI: 10.1124/pr.57.4.12  0.64
2005 Ebensperger G, Ebensperger R, Herrera EA, Riquelme RA, Sanhueza EM, Lesage F, Marengo JJ, Tejo RI, Llanos AJ, Reyes RV. Fetal brain hypometabolism during prolonged hypoxaemia in the llama. The Journal of Physiology. 567: 963-75. PMID 16037083 DOI: 10.1113/jphysiol.2005.094524  0.64
2004 Decressac S, Franco M, Bendahhou S, Warth R, Knauer S, Barhanin J, Lazdunski M, Lesage F. ARF6-dependent interaction of the TWIK1 K+ channel with EFA6, a GDP/GTP exchange factor foe ARF6 Embo Reports. 5: 1171-1175. PMID 15540117 DOI: 10.1038/sj.embor.7400292  0.64
2004 Nicolas MT, Lesage F, Reyes R, Barhanin J, Demêmes D. Localization of TREK-1, a two-pore-domain K+ channel in the peripheral vestibular system of mouse and rat. Brain Research. 1017: 46-52. PMID 15261098 DOI: 10.1016/j.brainres.2004.05.012  0.48
2004 Warth R, Barrière H, Meneton P, Bloch M, Thomas J, Tauc M, Heitzmann D, Romeo E, Verrey F, Mengual R, Guy N, Bendahhou S, Lesage F, Poujeol P, Barhanin J. Proximal renal tubular acidosis in TASK2 K+ channel-deficient mice reveals a mechanism for stabilizing bicarbonate transport Proceedings of the National Academy of Sciences of the United States of America. 101: 8215-8220. PMID 15141089 DOI: 10.1073/pnas.0400081101  0.64
2003 Gutman GA, Chandy KG, Adelman JP, Aiyar J, Bayliss DA, Clapham DE, Covarriubias M, Desir GV, Furuichi K, Ganetzky B, Garcia ML, Grissmer S, Jan LY, Karschin A, Kim D, ... ... Lesage F, et al. International Union of Pharmacology. XLI. Compendium of voltage-gated ion channels: potassium channels. Pharmacological Reviews. 55: 583-6. PMID 14657415 DOI: 10.1124/pr.55.4.9  0.64
2003 Chemin J, Girard C, Duprat F, Lesage F, Romey G, Lazdunski M. Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K+ channels. The Embo Journal. 22: 5403-11. PMID 14532113 DOI: 10.1093/emboj/cdg528  0.56
2003 Barriere H, Belfodil R, Rubera I, Tauc M, Lesage F, Poujeol C, Guy N, Barhanin J, Poujeol P. Role of TASK2 potassium channels regarding volume regulation in primary cultures of mouse proximal tubules Journal of General Physiology. 122: 177-190. PMID 12860925 DOI: 10.1085/jgp.200308820  0.64
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