Year |
Citation |
Score |
2023 |
Pérez MJ, Ibarra-García-Padilla R, Tang M, Porter GA, Johnson GVW, Quintanilla RA. Caspase-3 cleaved tau impairs mitochondrial function through the opening of the mitochondrial permeability transition pore. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 1870: 166898. PMID 37774936 DOI: 10.1016/j.bbadis.2023.166898 |
0.381 |
|
2023 |
Olesen MA, Quintanilla RA. Pathological Impact of Tau Proteolytical Process on Neuronal and Mitochondrial Function: a Crucial Role in Alzheimer's Disease. Molecular Neurobiology. PMID 37332018 DOI: 10.1007/s12035-023-03434-4 |
0.428 |
|
2023 |
Tapia-Monsalves C, Olesen MA, Villavicencio-Tejo F, Quintanilla RA. Cyclosporine A (CsA) prevents synaptic impairment caused by truncated tau by caspase-3. Molecular and Cellular Neurosciences. 103861. PMID 37182572 DOI: 10.1016/j.mcn.2023.103861 |
0.389 |
|
2022 |
Villavicencio-Tejo F, Olesen MA, Aránguiz A, Quintanilla RA. Activation of the Nrf2 Pathway Prevents Mitochondrial Dysfunction Induced by Caspase-3 Cleaved Tau: Implications for Alzheimer's Disease. Antioxidants (Basel, Switzerland). 11. PMID 35326165 DOI: 10.3390/antiox11030515 |
0.386 |
|
2020 |
Quintanilla RA, Tapia-Monsalves C, Vergara EH, Pérez MJ, Aranguiz A. Truncated Tau Induces Mitochondrial Transport Failure Through the Impairment of TRAK2 Protein and Bioenergetics Decline in Neuronal Cells. Frontiers in Cellular Neuroscience. 14: 175. PMID 32848607 DOI: 10.3389/fncel.2020.00175 |
0.372 |
|
2018 |
Tapia-Rojas C, Cabezas-Opazo F, Deaton CA, Vergara EH, Johnson GVW, Quintanilla RA. It's all about tau. Progress in Neurobiology. PMID 30605723 DOI: 10.1016/j.pneurobio.2018.12.005 |
0.425 |
|
2018 |
Pérez MJ, Jara C, Quintanilla RA. Contribution of Tau Pathology to Mitochondrial Impairment in Neurodegeneration. Frontiers in Neuroscience. 12: 441. PMID 30026680 DOI: 10.3389/fnins.2018.00441 |
0.364 |
|
2017 |
Pérez MJ, Vergara-Pulgar K, Jara C, Cabezas-Opazo F, Quintanilla RA. Caspase-Cleaved Tau Impairs Mitochondrial Dynamics in Alzheimer's Disease. Molecular Neurobiology. PMID 28084594 DOI: 10.1007/s12035-017-0385-x |
0.368 |
|
2016 |
Godoy JA, Lindsay CB, Quintanilla RA, Carvajal FJ, Cerpa W, Inestrosa NC. Quercetin Exerts Differential Neuroprotective Effects Against H2O2 and Aβ Aggregates in Hippocampal Neurons: the Role of Mitochondria. Molecular Neurobiology. PMID 27796749 DOI: 10.1007/S12035-016-0203-X |
0.444 |
|
2015 |
Pérez MJ, Quintanilla RA. Therapeutic Actions of the Thiazolidinediones in Alzheimer's Disease. Ppar Research. 2015: 957248. PMID 26587016 DOI: 10.1155/2015/957248 |
0.351 |
|
2015 |
Cabezas-Opazo FA, Vergara-Pulgar K, Pérez MJ, Jara C, Osorio-Fuentealba C, Quintanilla RA. Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer's Disease. Oxidative Medicine and Cellular Longevity. 2015: 509654. PMID 26221414 DOI: 10.1155/2015/509654 |
0.346 |
|
2014 |
Quintanilla RA, Utreras E, Cabezas-Opazo FA. Role of PPAR γ in the Differentiation and Function of Neurons. Ppar Research. 2014: 768594. PMID 25246934 DOI: 10.1155/2014/768594 |
0.37 |
|
2014 |
Quintanilla RA, von Bernhardi R, Godoy JA, Inestrosa NC, Johnson GV. Phosphorylated tau potentiates Aβ-induced mitochondrial damage in mature neurons. Neurobiology of Disease. 71: 260-9. PMID 25134729 DOI: 10.1016/j.nbd.2014.08.016 |
0.438 |
|
2013 |
Quintanilla RA, Godoy JA, Alfaro I, Cabezas D, von Bernhardi R, Bronfman M, Inestrosa NC. Thiazolidinediones promote axonal growth through the activation of the JNK pathway. Plos One. 8: e65140. PMID 23741474 DOI: 10.1371/Journal.Pone.0065140 |
0.323 |
|
2012 |
Quintanilla RA, Orellana JA, von Bernhardi R. Understanding risk factors for Alzheimer's disease: interplay of neuroinflammation, connexin-based communication and oxidative stress. Archives of Medical Research. 43: 632-44. PMID 23142264 DOI: 10.1016/j.arcmed.2012.10.016 |
0.354 |
|
2012 |
Quintanilla RA, Dolan PJ, Jin YN, Johnson GV. Truncated tau and Aβ cooperatively impair mitochondria in primary neurons. Neurobiology of Aging. 33: 619.e25-35. PMID 21450370 DOI: 10.1016/J.Neurobiolaging.2011.02.007 |
0.446 |
|
2010 |
Dinamarca MC, Sagal JP, Quintanilla RA, Godoy JA, Arrázola MS, Inestrosa NC. Amyloid-beta-Acetylcholinesterase complexes potentiate neurodegenerative changes induced by the Abeta peptide. Implications for the pathogenesis of Alzheimer's disease. Molecular Neurodegeneration. 5: 4. PMID 20205793 DOI: 10.1186/1750-1326-5-4 |
0.444 |
|
2009 |
Quintanilla RA, Johnson GV. Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease. Brain Research Bulletin. 80: 242-7. PMID 19622387 DOI: 10.1016/j.brainresbull.2009.07.010 |
0.329 |
|
2009 |
Quintanilla RA, Matthews-Roberson TA, Dolan PJ, Johnson GV. Caspase-cleaved tau expression induces mitochondrial dysfunction in immortalized cortical neurons: implications for the pathogenesis of Alzheimer disease. The Journal of Biological Chemistry. 284: 18754-66. PMID 19389700 DOI: 10.1074/Jbc.M808908200 |
0.343 |
|
2008 |
Matthews-Roberson TA, Quintanilla RA, Ding H, Johnson GV. Immortalized cortical neurons expressing caspase-cleaved tau are sensitized to endoplasmic reticulum stress induced cell death. Brain Research. 1234: 206-12. PMID 18718455 DOI: 10.1016/J.Brainres.2008.07.111 |
0.441 |
|
2007 |
Fuenzalida K, Quintanilla R, Ramos P, Piderit D, Fuentealba RA, Martinez G, Inestrosa NC, Bronfman M. Peroxisome proliferator-activated receptor gamma up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative stress and apoptosis. The Journal of Biological Chemistry. 282: 37006-15. PMID 17965419 DOI: 10.1074/Jbc.M700447200 |
0.526 |
|
2007 |
Mookherjee P, Quintanilla R, Roh MS, Zmijewska AA, Jope RS, Johnson GV. Mitochondrial-targeted active Akt protects SH-SY5Y neuroblastoma cells from staurosporine-induced apoptotic cell death. Journal of Cellular Biochemistry. 102: 196-210. PMID 17340627 DOI: 10.1002/Jcb.21287 |
0.391 |
|
2007 |
Orellana DI, Quintanilla RA, Maccioni RB. Neuroprotective effect of TNFalpha against the beta-amyloid neurotoxicity mediated by CDK5 kinase. Biochimica Et Biophysica Acta. 1773: 254-63. PMID 17150266 DOI: 10.1016/j.bbamcr.2006.10.010 |
0.643 |
|
2005 |
Orellana DI, Quintanilla RA, Gonzalez-Billault C, Maccioni RB. Role of the JAKs/STATs pathway in the intracellular calcium changes induced by interleukin-6 in hippocampal neurons. Neurotoxicity Research. 8: 295-304. PMID 16371324 DOI: 10.1007/BF03033983 |
0.582 |
|
2005 |
Santos MJ, Quintanilla RA, Toro A, Grandy R, Dinamarca MC, Godoy JA, Inestrosa NC. Peroxisomal proliferation protects from beta-amyloid neurodegeneration. The Journal of Biological Chemistry. 280: 41057-68. PMID 16204253 DOI: 10.1074/jbc.M505160200 |
0.453 |
|
2005 |
Inestrosa NC, Godoy JA, Quintanilla RA, Koenig CS, Bronfman M. Peroxisome proliferator-activated receptor γ is expressed in hippocampal neurons and its activation prevents β-amyloid neurodegeneration: Role of Wnt signaling Experimental Cell Research. 304: 91-104. PMID 15707577 DOI: 10.1016/j.yexcr.2004.09.032 |
0.397 |
|
2004 |
Quintanilla RA, Orellana DI, González-Billault C, Maccioni RB. Interleukin-6 induces Alzheimer-type phosphorylation of tau protein by deregulating the cdk5/p35 pathway. Experimental Cell Research. 295: 245-57. PMID 15051507 DOI: 10.1016/J.Yexcr.2004.01.002 |
0.592 |
|
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