Year |
Citation |
Score |
2023 |
Messelmani T, Le Goff A, Soncin F, Souguir Z, Merlier F, Maubon N, Legallais C, Leclerc E, Jellali R. Coculture model of a liver sinusoidal endothelial cell barrier and HepG2/C3a spheroids-on-chip in an advanced fluidic platform. Journal of Bioscience and Bioengineering. PMID 37973520 DOI: 10.1016/j.jbiosc.2023.10.006 |
0.636 |
|
2023 |
Morisseau L, Tokito F, Poulain S, Plaisance V, Pawlowski V, Kim SH, Legallais C, Jellali R, Sakai Y, Abderrahmani A, Leclerc E. Correction: Generation of β-like cell subtypes from differentiated human induced pluripotent stem cells in 3D spheroids. Molecular Omics. PMID 37800443 DOI: 10.1039/d3mo90033a |
0.533 |
|
2023 |
Morisseau L, Tokito F, Poulain S, Plaisance V, Pawlowski V, Kim SH, Legallais C, Jellali R, Sakai Y, Abderrahmani A, Leclerc E. Generation of β-like cell subtypes from differentiated human induced pluripotent stem cells in 3D spheroids. Molecular Omics. PMID 37698079 DOI: 10.1039/d3mo00050h |
0.552 |
|
2023 |
Madiedo-Podvrsan S, Sebillet L, Martinez T, Bacari S, Zhu F, Cattelin M, Leclerc E, Merlier F, Jellali R, Lacroix G, Vayssade M. Development of a lung-liver in vitro coculture model for inhalation-like toxicity assessment. Toxicology in Vitro : An International Journal Published in Association With Bibra. 92: 105641. PMID 37437822 DOI: 10.1016/j.tiv.2023.105641 |
0.302 |
|
2023 |
Messelmani T, Le Goff A, Soncin F, Gilard F, Souguir Z, Maubon N, Gakière B, Legallais C, Leclerc E, Jellali R. Investigation of the metabolomic crosstalk between liver sinusoidal endothelial cells and hepatocytes exposed to paracetamol using organ-on-chip technology. Toxicology. 153550. PMID 37209942 DOI: 10.1016/j.tox.2023.153550 |
0.634 |
|
2023 |
Danoy M, Poulain S, Jellali R, Scheidecker B, Tauran Y, Marjorie L, Johanna B, Kim SH, Kido T, Miyajima A, Sakai Y, Leclerc E. Transcriptomic and proteomic studies suggest the establishment of advanced zonation-like profiles in hiPSCs-derived LSECs and CPM-positive LPCs cocultured in a fluidic microenvironment. Hepatology Research : the Official Journal of the Japan Society of Hepatology. PMID 36866738 DOI: 10.1111/hepr.13893 |
0.309 |
|
2022 |
Essaouiba A, Jellali R, Gilard F, Gakière B, Okitsu T, Legallais C, Sakai Y, Leclerc E. Investigation of the Exometabolomic Profiles of Rat Islets of Langerhans Cultured in Microfluidic Biochip. Metabolites. 12. PMID 36557308 DOI: 10.3390/metabo12121270 |
0.631 |
|
2022 |
Etxeberria L, Messelmani T, Badiola JH, Llobera A, Fernandez L, Vilas-Vilela JL, Leclerc E, Legallais C, Jellali R, Zaldua AM. Validation of HepG2/C3A Cell Cultures in Cyclic Olefin Copolymer Based Microfluidic Bioreactors. Polymers. 14. PMID 36365472 DOI: 10.3390/polym14214478 |
0.65 |
|
2022 |
Messelmani T, Le Goff A, Souguir Z, Maes V, Roudaut M, Vandenhaute E, Maubon N, Legallais C, Leclerc E, Jellali R. Development of Liver-on-Chip Integrating a Hydroscaffold Mimicking the Liver's Extracellular Matrix. Bioengineering (Basel, Switzerland). 9. PMID 36134989 DOI: 10.3390/bioengineering9090443 |
0.655 |
|
2022 |
Essaouiba A, Jellali R, Poulain S, Tokito F, Gilard F, Gakière B, Kim SH, Legallais C, Sakai Y, Leclerc E. Analysis of the transcriptome and metabolome of pancreatic spheroids derived from human induced pluripotent stem cells and matured in an organ-on-a-chip. Molecular Omics. PMID 35916309 DOI: 10.1039/d2mo00132b |
0.606 |
|
2022 |
Messelmani T, Morisseau L, Sakai Y, Legallais C, Le Goff A, Leclerc E, Jellali R. Liver organ-on-chip models for toxicity studies and risk assessment. Lab On a Chip. PMID 35694831 DOI: 10.1039/d2lc00307d |
0.642 |
|
2021 |
Boulais L, Jellali R, Pereira U, Leclerc E, Bencherif SA, Legallais C. Cryogel-Integrated Biochip for Liver Tissue Engineering. Acs Applied Bio Materials. 4: 5617-5626. PMID 35006744 DOI: 10.1021/acsabm.1c00425 |
0.639 |
|
2021 |
Danoy M, Tauran Y, Poulain S, Jellali R, Bruce J, Leduc M, Le Gall M, Koui Y, Arakawa H, Gilard F, Gakiere B, Kato Y, Plessy C, Kido T, Miyajima A, ... ... Leclerc E, et al. Investigation of the hepatic development in the coculture of hiPSCs-derived LSECs and HLCs in a fluidic microenvironment. Apl Bioengineering. 5: 026104. PMID 34027283 DOI: 10.1063/5.0041227 |
0.321 |
|
2021 |
Jellali R, Jacques S, Essaouiba A, Gilard F, Letourneur F, Gakière B, Legallais C, Leclerc E. Investigation of steatosis profiles induced by pesticides using liver organ-on-chip model and omics analysis. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 152: 112155. PMID 33775782 DOI: 10.1016/j.fct.2021.112155 |
0.615 |
|
2021 |
Essaouiba A, Jellali R, Shinohara M, Scheidecker B, Legallais C, Sakai Y, Leclerc E. Analysis of the behavior of 2D monolayers and 3D spheroid human pancreatic beta cells derived from induced pluripotent stem cells in a microfluidic environment. Journal of Biotechnology. 330: 45-56. PMID 33617908 DOI: 10.1016/j.jbiotec.2021.02.009 |
0.592 |
|
2021 |
Danoy M, Tauran Y, Poulain S, Jellali R, Bruce J, Leduc M, Le Gall M, Gilard F, Kido T, Arakawa H, Araya K, Mori D, Kato Y, Kusuhara H, Plessy C, ... ... Leclerc E, et al. Multi-omics analysis of hiPSCs-derived HLCs matured on-chip revealed patterns typical of liver regeneration. Biotechnology and Bioengineering. PMID 33404112 DOI: 10.1002/bit.27667 |
0.339 |
|
2020 |
Danoy M, Tauran Y, Poulain S, Arakawa H, Mori D, Araya K, Kato S, Kido T, Kusuhara H, Kato Y, Miyajima A, Plessy C, Sakai Y, Leclerc E. Analysis of hiPSCs differentiation toward hepatocyte-like cells upon extended exposition to oncostatin. Differentiation; Research in Biological Diversity. 114: 36-48. PMID 32563741 DOI: 10.1016/J.Diff.2020.05.006 |
0.454 |
|
2020 |
Essaouiba A, Okitsu T, Jellali R, Shinohara M, Danoy M, Tauran Y, Legallais C, Sakai Y, Leclerc E. Microwell-based pancreas-on-chip model enhances genes expression and functionality of rat islets of Langerhans. Molecular and Cellular Endocrinology. 110892. PMID 32531418 DOI: 10.1016/J.Mce.2020.110892 |
0.601 |
|
2020 |
Danoy M, Poulain S, Lereau-Bernier M, Kato S, Scheidecker B, Kido T, Miyajima A, Sakai Y, Plessy C, Leclerc E. Characterization of liver zonation-like transcriptomic patterns in HLCs derived from hiPSCs in a microfluidic biochip environment. Biotechnology Progress. e3013. PMID 32364651 DOI: 10.1002/Btpr.3013 |
0.441 |
|
2020 |
Jellali R, Poulain S, Bernier ML, Gilard F, Tauran Y, Kato S, Danoy M, Segard BD, Kido T, Miyajima A, Plessy C, Sakai Y, Leclerc E. Integration of metabolomic and transcriptomic profiling to compare two protocols of differentiation of human induced pluripotent stem cells into hepatocytes Process Biochemistry. 88: 138-147. DOI: 10.1016/J.Procbio.2019.09.034 |
0.438 |
|
2020 |
Essaouiba A, Okitsu T, Kinoshita R, Jellali R, Shinohara M, Danoy M, Legallais C, Sakai Y, Leclerc E. Development of a pancreas-liver organ-on-chip coculture model for organ-to-organ interaction studies Biochemical Engineering Journal. 107783. DOI: 10.1016/J.Bej.2020.107783 |
0.599 |
|
2020 |
Danoy M, Poulain S, Jelalli R, Gilard F, Kato S, Plessy C, Kido T, Miyajima A, Sakai Y, Leclerc E. Integration of metabolomic and transcriptomic profiles of hiPSCs-derived hepatocytes in a microfluidic environment Biochemical Engineering Journal. 155: 107490. DOI: 10.1016/J.Bej.2020.107490 |
0.457 |
|
2020 |
Danoy M, Poulain S, Lereau‐Bernier M, Kato S, Scheidecker B, Kido T, Miyajima A, Sakai Y, Plessy C, Leclerc E. Author response for "Characterization of liver zonation‐like transcriptomic patterns in HLCs derived from hiPSCs in a microfluidic biochip environment" Biotechnology Progress. DOI: 10.1002/Btpr.3013/V2/Response1 |
0.333 |
|
2019 |
Jellali R, Lereau Bernier M, Tauran Y, Gilard F, Danoy M, Kido T, Miyajima A, Sakai Y, Leclerc E. Metabolomic profiling during the differentiation of human induced pluripotent stem cells into hepatocyte-like cells. Differentiation; Research in Biological Diversity. 112: 17-26. PMID 31869687 DOI: 10.1016/J.Diff.2019.10.006 |
0.413 |
|
2019 |
Sasaki Y, Leclerc É, Hamedpour V, Kubota R, Takizawa SY, Sakai Y, Minami T. Simplest Chemosensor Array for Phosphorylated Saccharides. Analytical Chemistry. PMID 31714059 DOI: 10.1021/Acs.Analchem.9B03578 |
0.324 |
|
2019 |
Matsumoto S, Safitri AR, Danoy M, Maekawa T, Kinoshita H, Shinohara M, Sakai Y, Fujii T, Leclerc E. Investigation of the hepatic respiration and liver zonation on rat hepatocytes using an integrated oxygen biosensor in a microscale device. Biotechnology Progress. e2854. PMID 31131557 DOI: 10.1002/Btpr.2854 |
0.38 |
|
2019 |
Danoy M, Bernier ML, Kimura K, Poulain S, Kato S, Mori D, Kido T, Plessy C, Kusuhara H, Miyajima A, Sakai Y, Leclerc E. Optimized protocol for the hepatic differentiation of iPSCs in a fluidic microenvironment. Biotechnology and Bioengineering. PMID 30883676 DOI: 10.1002/Bit.26970 |
0.447 |
|
2019 |
Lereau Bernier M, Poulain S, Tauran Y, Danoy M, Shinohara M, Kimura K, Segard BD, Kato S, Kido T, Miyajima A, Sakai Y, Plessy C, Leclerc É. Profiling of derived-hepatocyte progenitors from induced pluripotent stem cells using nanoCAGE promoter analysis Biochemical Engineering Journal. 142: 7-17. DOI: 10.1016/J.Bej.2018.11.001 |
0.401 |
|
2018 |
Jellali R, Gilard F, Pandolfi V, Legendre A, Fleury MJ, Paullier P, Legallais C, Leclerc E. Metabolomics-on-a-chip approach to study hepatotoxicity of DDT, permethrin and their mixtures. Journal of Applied Toxicology : Jat. PMID 29659035 DOI: 10.1002/Jat.3624 |
0.626 |
|
2018 |
Jellali R, Zeller P, Gilard F, Legendre A, Fleury MJ, Jacques S, Tcherkez G, Leclerc E. Effects of DDT and permethrin on rat hepatocytes cultivated in microfluidic biochips: Metabolomics and gene expression study. Environmental Toxicology and Pharmacology. 59: 1-12. PMID 29477483 DOI: 10.1016/J.Etap.2018.02.004 |
0.4 |
|
2018 |
Matsumoto S, Leclerc E, Maekawa T, Kinoshita H, Shinohara M, Komori K, Sakai Y, Fujii T. Integration of an oxygen sensor into a polydymethylsiloxane hepatic culture device for two-dimensional gradient characterization Sensors and Actuators B: Chemical. 273: 1062-1069. DOI: 10.1016/J.Snb.2018.05.053 |
0.379 |
|
2017 |
Merlier F, Jellali R, Leclerc E. Online monitoring of hepatic rat metabolism by coupling a liver biochip and a mass spectrometer. The Analyst. PMID 28891561 DOI: 10.1039/C7An00973A |
0.445 |
|
2017 |
Leclerc E, Duval JL, Egles C, Ihida S, Toshiyoshi H, Tixier-Mita A. In vitro cyto-biocompatibility study of thin-film transistors substrates using an organotypic culture method. Journal of Materials Science. Materials in Medicine. 28: 4. PMID 27878736 DOI: 10.1007/S10856-016-5815-1 |
0.372 |
|
2017 |
Shaik FA, Cathcart G, Ihida S, Lereau-Bernier M, Leclerc E, Sakai Y, Toshiyoshi H, Tixier-Mita A. Thin-film-transistor array: an exploratory attempt for high throughput cell manipulation using electrowetting principle Journal of Micromechanics and Microengineering. 27: 54001. DOI: 10.1088/1361-6439/Aa66E8 |
0.356 |
|
2017 |
Lignel S, Salsac A, Drelich A, Leclerc E, Pezron I. Water-in-oil droplet formation in a flow-focusing microsystem using pressure- and flow rate-driven pumps Colloids and Surfaces a: Physicochemical and Engineering Aspects. 531: 164-172. DOI: 10.1016/J.Colsurfa.2017.07.065 |
0.744 |
|
2016 |
Leclerc E, Kimura K, Shinohara M, Danoy M, Le Gall M, Kido T, Miyajima A, Fujii T, Sakai Y. Comparison of the transcriptomic profile of hepatic human induced pluripotent stem like cells cultured in plates and in a 3D microscale dynamic environment. Genomics. PMID 27913249 DOI: 10.1016/J.Ygeno.2016.11.008 |
0.464 |
|
2016 |
Zeller P, Legendre A, Jacques S, Fleury MJ, Gilard F, Tcherkez G, Leclerc E. Hepatocytes cocultured with Sertoli cells in bioreactor favors Sertoli barrier tightness in rat. Journal of Applied Toxicology : Jat. PMID 27440042 DOI: 10.1002/Jat.3360 |
0.477 |
|
2016 |
Jellali R, Duval JL, Leclerc E. Analysis of the biocompatibility of perfluoropolyether dimethacrylate network using an organotypic method. Materials Science & Engineering. C, Materials For Biological Applications. 65: 295-302. PMID 27157755 DOI: 10.1016/J.Msec.2016.04.057 |
0.413 |
|
2016 |
Jellali R, Bricks T, Jacques S, Fleury MJ, Paullier P, Merlier F, Leclerc E. Long-term human primary hepatocyte cultures in a microfluidic liver biochip show maintenance of mRNA levels and higher drug metabolism compared with Petri cultures. Biopharmaceutics & Drug Disposition. 37: 264-75. PMID 27037683 DOI: 10.1002/Bdd.2010 |
0.812 |
|
2016 |
Willemin ME, Desmots S, Le Grand R, Lestremau F, Zeman FA, Leclerc E, Moesch C, Brochot C. PBPK modeling of the cis- and trans-permethrin isomers and their major urinary metabolites in rats. Toxicology and Applied Pharmacology. 294: 65-77. PMID 26802525 DOI: 10.1016/J.Taap.2016.01.011 |
0.728 |
|
2016 |
Leclerc E, Hamon J, Bois FY. Investigation of ifosfamide and chloroacetaldehyde renal toxicity through integration of in vitro liver-kidney microfluidic data and pharmacokinetic-system biology models. Journal of Applied Toxicology : Jat. 36: 330-9. PMID 26152902 DOI: 10.1002/Jat.3191 |
0.389 |
|
2016 |
Jellali R, Paullier P, Fleury M, Leclerc E. Liver and kidney cells cultures in a new perfluoropolyether biochip Sensors and Actuators B: Chemical. 229: 396-407. DOI: 10.1016/J.Snb.2016.01.141 |
0.48 |
|
2015 |
Leclerc E, Hamon J, Claude I, Jellali R, Naudot M, Bois F. Investigation of acetaminophen toxicity in HepG2/C3a microscale cultures using a system biology model of glutathione depletion. Cell Biology and Toxicology. 31: 173-85. PMID 25956491 DOI: 10.1007/S10565-015-9302-0 |
0.804 |
|
2015 |
Willemin ME, Kadar A, de Sousa G, Leclerc E, Rahmani R, Brochot C. In vitro human metabolism of permethrin isomers alone or as a mixture and the formation of the major metabolites in cryopreserved primary hepatocytes. Toxicology in Vitro : An International Journal Published in Association With Bibra. 29: 803-12. PMID 25765475 DOI: 10.1016/J.Tiv.2015.03.003 |
0.745 |
|
2015 |
Zeller P, Bricks T, Vidal G, Jacques S, Anton PM, Leclerc E. Multiparametric temporal analysis of the Caco-2/TC7 demonstrated functional and differentiated monolayers as early as 14 days of culture. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 72: 1-11. PMID 25725134 DOI: 10.1016/J.Ejps.2015.02.013 |
0.797 |
|
2015 |
Bricks T, Hamon J, Fleury MJ, Jellali R, Merlier F, Herpe YE, Seyer A, Regimbeau JM, Bois F, Leclerc E. Investigation of omeprazole and phenacetin first-pass metabolism in humans using a microscale bioreactor and pharmacokinetic models. Biopharmaceutics & Drug Disposition. 36: 275-93. PMID 25678106 DOI: 10.1002/Bdd.1940 |
0.815 |
|
2014 |
Prot JM, Maciel L, Bricks T, Merlier F, Cotton J, Paullier P, Bois FY, Leclerc E. First pass intestinal and liver metabolism of paracetamol in a microfluidic platform coupled with a mathematical modeling as a means of evaluating ADME processes in humans. Biotechnology and Bioengineering. 111: 2027-40. PMID 24954399 DOI: 10.1002/Bit.25232 |
0.799 |
|
2014 |
Leclerc E, Hamon J, Legendre A, Bois FY. Integration of pharmacokinetic and NRF2 system biology models to describe reactive oxygen species production and subsequent glutathione depletion in liver microfluidic biochips after flutamide exposure. Toxicology in Vitro : An International Journal Published in Association With Bibra. 28: 1230-41. PMID 24929096 DOI: 10.1016/J.Tiv.2014.05.003 |
0.392 |
|
2014 |
Legendre A, Jacques S, Dumont F, Cotton J, Paullier P, Fleury MJ, Leclerc E. Investigation of the hepatotoxicity of flutamide: pro-survival/apoptotic and necrotic switch in primary rat hepatocytes characterized by metabolic and transcriptomic profiles in microfluidic liver biochips. Toxicology in Vitro : An International Journal Published in Association With Bibra. 28: 1075-87. PMID 24793618 DOI: 10.1016/J.Tiv.2014.04.008 |
0.476 |
|
2014 |
Bricks T, Paullier P, Legendre A, Fleury MJ, Zeller P, Merlier F, Anton PM, Leclerc E. Development of a new microfluidic platform integrating co-cultures of intestinal and liver cell lines Toxicology in Vitro. 28: 885-895. PMID 24662032 DOI: 10.1016/J.Tiv.2014.02.005 |
0.827 |
|
2014 |
Baudoin R, Alberto G, Legendre A, Paullier P, Naudot M, Fleury MJ, Jacques S, Griscom L, Leclerc E. Investigation of expression and activity levels of primary rat hepatocyte detoxication genes under various flow rates and cell densities in microfluidic biochips. Biotechnology Progress. 30: 401-10. PMID 24376233 DOI: 10.1002/Btpr.1857 |
0.809 |
|
2014 |
Baudoin R, Legendre A, Jacques S, Cotton J, Bois F, Leclerc E. Evaluation of a liver microfluidic biochip to predict in vivo clearances of seven drugs in rats. Journal of Pharmaceutical Sciences. 103: 706-18. PMID 24338834 DOI: 10.1002/Jps.23796 |
0.77 |
|
2014 |
Naudot M, Paullier P, Dargent T, Senez V, Kharboutly Z, Claude I, Leclerc E. Characterisation of early HepG2/3a cell response to a microfluidic culture in liver biochips using multi-parametric real time image processing Sensors and Actuators B: Chemical. 199: 433-445. DOI: 10.1016/J.Snb.2014.03.074 |
0.801 |
|
2014 |
Lignel S, Drelich A, Sunagatullina D, Clausse D, Leclerc E, Pezron I. Differential scanning calorimetry analysis of W/O emulsions prepared by miniature scale magnetic agitation and microfluidics Canadian Journal of Chemical Engineering. 92: 337-343. DOI: 10.1002/Cjce.21925 |
0.744 |
|
2013 |
Legendre A, Baudoin R, Alberto G, Paullier P, Naudot M, Bricks T, Brocheton J, Jacques S, Cotton J, Leclerc E. Metabolic characterization of primary rat hepatocytes cultivated in parallel microfluidic biochips. Journal of Pharmaceutical Sciences. 102: 3264-76. PMID 23423727 DOI: 10.1002/Jps.23466 |
0.79 |
|
2013 |
Choucha-Snouber L, Aninat C, Grsicom L, Madalinski G, Brochot C, Poleni PE, Razan F, Guillouzo CG, Legallais C, Corlu A, Leclerc E. Investigation of ifosfamide nephrotoxicity induced in a liver-kidney co-culture biochip. Biotechnology and Bioengineering. 110: 597-608. PMID 22887128 DOI: 10.1002/Bit.24707 |
0.68 |
|
2013 |
Choucha Snouber L, Bunescu A, Naudot M, Legallais C, Brochot C, Dumas ME, Elena-Herrmann B, Leclerc E. Metabolomics-on-a-chip of hepatotoxicity induced by anticancer drug flutamide and Its active metabolite hydroxyflutamide using HepG2/C3a microfluidic biochips. Toxicological Sciences : An Official Journal of the Society of Toxicology. 132: 8-20. PMID 22843567 DOI: 10.1093/Toxsci/Kfs230 |
0.815 |
|
2013 |
Baudoin R, Prot JM, Nicolas G, Brocheton J, Brochot C, Legallais C, Benech H, Leclerc E. Evaluation of seven drug metabolisms and clearances by cryopreserved human primary hepatocytes cultivated in microfluidic biochips. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 43: 140-52. PMID 22830982 DOI: 10.3109/00498254.2012.706725 |
0.787 |
|
2013 |
Bricks T, Paullier P, Fleury M, Merlier F, Leclerc E. Feasibility study of a new microfluidic device consisting in the coculture of intestinal and hepatic cells Toxicology Letters. 221: S148. DOI: 10.1016/J.Toxlet.2013.05.300 |
0.785 |
|
2012 |
Ouattara DA, Prot JM, Bunescu A, Dumas ME, Elena-Herrmann B, Leclerc E, Brochot C. Metabolomics-on-a-chip and metabolic flux analysis for label-free modeling of the internal metabolism of HepG2/C3A cells. Molecular Biosystems. 8: 1908-20. PMID 22618574 DOI: 10.1039/C2Mb25049G |
0.792 |
|
2012 |
Choucha Snouber L, Jacques S, Monge M, Legallais C, Leclerc E. Transcriptomic analysis of the effect of ifosfamide on MDCK cells cultivated in microfluidic biochips. Genomics. 100: 27-34. PMID 22580237 DOI: 10.1016/J.Ygeno.2012.05.001 |
0.59 |
|
2012 |
Cheng S, Prot JM, Leclerc E, Bois FY. Zonation related function and ubiquitination regulation in human hepatocellular carcinoma cells in dynamic vs. static culture conditions. Bmc Genomics. 13: 54. PMID 22296956 DOI: 10.1186/1471-2164-13-54 |
0.767 |
|
2012 |
Shintu L, Baudoin R, Navratil V, Prot JM, Pontoizeau C, Defernez M, Blaise BJ, Domange C, Péry AR, Toulhoat P, Legallais C, Brochot C, Leclerc E, Dumas ME. Metabolomics-on-a-chip and predictive systems toxicology in microfluidic bioartificial organs. Analytical Chemistry. 84: 1840-8. PMID 22242722 DOI: 10.1021/Ac2011075 |
0.801 |
|
2012 |
Prot JM, Bunescu A, Elena-Herrmann B, Aninat C, Snouber LC, Griscom L, Razan F, Bois FY, Legallais C, Brochot C, Corlu A, Dumas ME, Leclerc E. Predictive toxicology using systemic biology and liver microfluidic "on chip" approaches: application to acetaminophen injury. Toxicology and Applied Pharmacology. 259: 270-80. PMID 22230336 DOI: 10.1016/J.Taap.2011.12.017 |
0.804 |
|
2012 |
Prot JM, Leclerc E. The current status of alternatives to animal testing and predictive toxicology methods using liver microfluidic biochips. Annals of Biomedical Engineering. 40: 1228-43. PMID 22160577 DOI: 10.1007/S10439-011-0480-5 |
0.812 |
|
2012 |
Snouber LC, Letourneur F, Chafey P, Broussard C, Monge M, Legallais C, Leclerc E. Analysis of transcriptomic and proteomic profiles demonstrates improved Madin-Darby canine kidney cell function in a renal microfluidic biochip. Biotechnology Progress. 28: 474-84. PMID 22095740 DOI: 10.1002/Btpr.743 |
0.638 |
|
2012 |
Baudoin R, Alberto G, Paullier P, Legallais C, Leclerc E. Parallelized microfluidic biochips in multi well plate applied to liver tissue engineering Sensors and Actuators B: Chemical. 173: 919-926. DOI: 10.1016/J.Snb.2012.06.050 |
0.829 |
|
2011 |
Prot JM, Briffaut AS, Letourneur F, Chafey P, Merlier F, Grandvalet Y, Legallais C, Leclerc E. Integrated proteomic and transcriptomic investigation of the acetaminophen toxicity in liver microfluidic biochip. Plos One. 6: e21268. PMID 21857903 DOI: 10.1371/Journal.Pone.0021268 |
0.83 |
|
2011 |
Ramello C, Paullier P, Ould-Dris A, Monge M, Legallais C, Leclerc E. Investigation into modification of mass transfer kinetics by acrolein in a renal biochip. Toxicology in Vitro : An International Journal Published in Association With Bibra. 25: 1123-31. PMID 21457771 DOI: 10.1016/J.Tiv.2011.03.017 |
0.582 |
|
2011 |
Prot JM, Aninat C, Griscom L, Razan F, Brochot C, Guillouzo CG, Legallais C, Corlu A, Leclerc E. Improvement of HepG2/C3a cell functions in a microfluidic biochip. Biotechnology and Bioengineering. 108: 1704-15. PMID 21337338 DOI: 10.1002/Bit.23104 |
0.828 |
|
2011 |
Prot JM, Videau O, Brochot C, Legallais C, Bénech H, Leclerc E. A cocktail of metabolic probes demonstrates the relevance of primary human hepatocyte cultures in a microfluidic biochip for pharmaceutical drug screening. International Journal of Pharmaceutics. 408: 67-75. PMID 21295126 DOI: 10.1016/J.Ijpharm.2011.01.054 |
0.826 |
|
2011 |
Chu TX, Salsac AV, Leclerc E, Barthès-Biesel D, Wurtz H, Edwards-Lévy F. Comparison between measurements of elasticity and free amino group content of ovalbumin microcapsule membranes: Discrimination of the cross-linking degree Journal of Colloid and Interface Science. 355: 81-88. PMID 21194705 DOI: 10.1016/J.Jcis.2010.11.038 |
0.555 |
|
2011 |
Baudoin R, Griscom L, Prot JM, Legallais C, Leclerc E. Behavior of HepG2/C3A cell cultures in a microfluidic bioreactor Biochemical Engineering Journal. 53: 172-181. DOI: 10.1016/J.Bej.2010.10.007 |
0.823 |
|
2010 |
Leclerc E, Duval JL, Jalabert L. Migration of liver and kidney explants inside trapezoidal PDMS microchannels Materials Science and Engineering C. 30: 1190-1196. DOI: 10.1016/J.Msec.2010.06.016 |
0.33 |
|
2010 |
Ould-Dris A, Paullier P, Griscom L, Legallais C, Leclerc E. Analysis of the mass transfers in an artificial kidney microchip Journal of Membrane Science. 352: 116-125. DOI: 10.1016/J.Memsci.2010.02.007 |
0.568 |
|
2010 |
He P, Barthès-Biesel D, Leclerc E. Flow of two immiscible liquids with low viscosity in Y shaped microfluidic systems: effect of geometry Microfluidics and Nanofluidics. 9: 293-301. DOI: 10.1007/S10404-009-0546-Y |
0.751 |
|
2009 |
Leclerc E, Duval JL, Pezron I, Nadaud F. Behaviors of liver and kidney explants from chicken embryos inside plasma treated PDMS microchannels Materials Science and Engineering C. 29: 861-868. DOI: 10.1016/J.Msec.2008.07.019 |
0.382 |
|
2008 |
Debuisson D, Treizebré A, Houssin T, Leclerc E, Bartès-Biesel D, Legrand D, Mazurier J, Arscott S, Bocquet B, Senez V. Nanoscale devices for online dielectric spectroscopy of biological cells. Physiological Measurement. 29: S213-25. PMID 18544801 DOI: 10.1088/0967-3334/29/6/S19 |
0.32 |
|
2008 |
Leclerc E, El Kirat K, Griscom L. In situ micropatterning technique by cell crushing for co-cultures inside microfluidic biochips. Biomedical Microdevices. 10: 169-77. PMID 17849187 DOI: 10.1007/S10544-007-9122-Y |
0.443 |
|
2007 |
Baudoin R, Griscom L, Monge M, Legallais C, Leclerc E. Development of a renal microchip for in vitro distal tubule models. Biotechnology Progress. 23: 1245-53. PMID 17725364 DOI: 10.1021/Bp0603513 |
0.815 |
|
2007 |
Baudoin R, Corlu A, Griscom L, Legallais C, Leclerc E. Trends in the development of microfluidic cell biochips for in vitro hepatotoxicity. Toxicology in Vitro : An International Journal Published in Association With Bibra. 21: 535-44. PMID 17188836 DOI: 10.1016/J.Tiv.2006.11.004 |
0.815 |
|
2007 |
Leclerc E, Baudoin R, Corlu A, Griscom L, Luc Duval J, Legallais C. Selective control of liver and kidney cells migration during organotypic cocultures inside fibronectin-coated rectangular silicone microchannels. Biomaterials. 28: 1820-9. PMID 17178157 DOI: 10.1016/J.Biomaterials.2006.11.044 |
0.803 |
|
2006 |
Leclerc E, Corlu A, Griscom L, Baudoin R, Legallais C. Guidance of liver and kidney organotypic cultures inside rectangular silicone microchannels. Biomaterials. 27: 4109-19. PMID 16616777 DOI: 10.1016/J.Biomaterials.2006.03.031 |
0.803 |
|
2006 |
Leclerc E, David B, Griscom L, Lepioufle B, Sakai Y, Fujii T, Legallais C. Perfusion culture of mammalian cells in microfluidic environments for tissue engineering applications Houille Blanche-Revue Internationale De L Eau. 3: 56-59. DOI: 10.1051/Lhb:200603008 |
0.658 |
|
2006 |
Baudoin R, Griscom L, Legallais C, Leclerc E. Development of a microfluidic device for in vitro liver model Journal of Biomechanics. 39: S253-S254. DOI: 10.1016/S0021-9290(06)83963-1 |
0.787 |
|
2005 |
Leclerc E, David B, Griscom L, Lepioufle B, Fujii T, Layrolle P, Legallaisa C. Study of osteoblastic cells in a microfluidic environment. Biomaterials. 27: 586-95. PMID 16026825 DOI: 10.1016/J.Biomaterials.2005.06.002 |
0.418 |
|
2005 |
Leclerc E, Furukawa KS, Miyata F, Sakai Y, Ushida T, Fujii T. Fabrication of microstructures in photosensitive biodegradable polymers for tissue engineering applications. Biomaterials. 25: 4683-90. PMID 15120514 DOI: 10.1016/J.Biomaterials.2003.10.060 |
0.326 |
|
2004 |
Leclerc E, Sakai Y, Fujii T. Microfluidic PDMS (polydimethylsiloxane) bioreactor for large-scale culture of hepatocytes. Biotechnology Progress. 20: 750-5. PMID 15176878 DOI: 10.1021/Bp0300568 |
0.414 |
|
2004 |
Leclerc E, Miyata F, Furukawa KS, Ushida T, Sakai Y, Fujii T. Effect on liver cells of stepwise microstructures fabricated in a photosensitive biodegradable polymer by softlithography Materials Science and Engineering: C. 24: 349-354. DOI: 10.1016/J.Msec.2003.12.004 |
0.396 |
|
2004 |
Leclerc E, Sakai Y, Fujii T. Perfusion culture of fetal human hepatocytes in microfluidic environments Biochemical Engineering Journal. 20: 143-148. DOI: 10.1016/J.Bej.2003.09.010 |
0.473 |
|
2003 |
Leclerc E, Sakai Y, Fujii T. Biomedical Microdevices. 5: 109-114. DOI: 10.1023/A:1024583026925 |
0.458 |
|
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