| Year |
Citation |
Score |
| 2023 |
Wimmer T, Sawinski H, Urban AM, Motlik J, Stieger K. Rapid and Reliable Quantification of Prime Editing Targeting Within the Porcine Gene Using a Bioluminescence Resonance Energy Transfer-Based Sensor. Nucleic Acid Therapeutics. PMID 36857739 DOI: 10.1089/nat.2022.0037 |
0.316 |
|
| 2020 |
Rohiwal SS, Dvorakova N, Klima J, Vaskovicova M, Senigl F, Slouf M, Pavlova E, Stepanek P, Babuka D, Benes H, Ellederova Z, Stieger K. Polyethylenimine based magnetic nanoparticles mediated non-viral CRISPR/Cas9 system for genome editing. Scientific Reports. 10: 4619-4619. PMID 32165679 DOI: 10.1038/S41598-020-61465-6 |
0.371 |
|
| 2020 |
Pasquini G, Cora V, Swiersy A, Achberger K, Antkowiak L, Müller B, Wimmer T, Fraschka SA, Casadei N, Ueffing M, Liebau S, Stieger K, Busskamp V. Using Transcriptomic Analysis to Assess Double-Strand Break Repair Activity: Towards Precise in vivo Genome Editing. International Journal of Molecular Sciences. 21. PMID 32085662 DOI: 10.3390/Ijms21041380 |
0.394 |
|
| 2019 |
Andrassi-Darida M, Mais C, Stieger K, Lorenz B. [Fluorescence Angiography-assisted Management of Recurrences in Aggressive Posterior Retinopathy of Prematurity (APROP) after Intravitreal Monotherapy with 0.312 mg Bevacizumab]. Klinische Monatsblatter Fur Augenheilkunde. PMID 31770787 DOI: 10.1055/A-1012-1999 |
0.311 |
|
| 2018 |
Chung DC, Bertelsen M, Lorenz B, Pennesi ME, Leroy BP, Hamel CP, Pierce E, Sallum J, Larsen M, Stieger K, Preising M, Weleber R, Yang P, Place E, Liu E, et al. The Natural History of Inherited Retinal Dystrophy due to Biallelic Mutations in the RPE65 Gene. American Journal of Ophthalmology. PMID 30268864 DOI: 10.1016/J.Ajo.2018.09.024 |
0.377 |
|
| 2018 |
Schlegel J, Hoffmann J, Röll D, Müller B, Günther S, Zhang W, Janise A, Vössing C, Fühler B, Neidhardt J, Khanna H, Lorenz B, Stieger K. Toward genome editing in X-linked RP-development of a mouse model with specific treatment relevant features. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 30213530 DOI: 10.1016/J.Trsl.2018.08.006 |
0.459 |
|
| 2018 |
Yanik M, Ponnam SPG, Wimmer T, Trimborn L, Müller C, Gambert I, Ginsberg J, Janise A, Domicke J, Wende W, Lorenz B, Stieger K. Development of a Reporter System to Explore MMEJ in the Context of Replacing Large Genomic Fragments. Molecular Therapy. Nucleic Acids. 11: 407-415. PMID 29858075 DOI: 10.1016/J.Omtn.2018.03.010 |
0.351 |
|
| 2018 |
Müller B, Ellinwood NM, Lorenz B, Stieger K. Detection of DNA Double Strand Breaks by γH2AX Does Not Result in 53bp1 Recruitment in Mouse Retinal Tissues. Frontiers in Neuroscience. 12: 286. PMID 29765300 DOI: 10.3389/Fnins.2018.00286 |
0.467 |
|
| 2018 |
Bowl W, Knobloch R, Schweinfurth S, Holve K, Stieger K, Lorenz B. Structure-Function Correlation in Hemianopic Vision Loss in Children Aged 3-6 Years Using OCT and SVOP, and Comparison with Adult Eyes. Ophthalmic Research. PMID 29332093 DOI: 10.1159/000480296 |
0.324 |
|
| 2018 |
Rohiwal SS, Klima J, Vaškovičová M, Senigl F, Šlouf M, Pavlova E, Štěpánek P, Stieger K, Ellederova Z. I08 Nanoparticle based CRSIPR/CAS gene editing system to treat huntington’s disease Journal of Neurology, Neurosurgery, and Psychiatry. 89. DOI: 10.1136/Jnnp-2018-Ehdn.244 |
0.362 |
|
| 2017 |
Bowl W, Schweinfurth S, Holve K, Stieger K, Lorenz B, Andrassi-Darida M. [The Impact of Macular Development on Full-field and Multifocal ERG in Extremely Preterm-born Children with and without Acute Retinopathy of Prematurity]. Klinische Monatsblatter Fur Augenheilkunde. 234: 1235-1242. PMID 29025171 DOI: 10.1055/S-0043-118830 |
0.357 |
|
| 2017 |
Matet A, Kostic C, Bemelmans AP, Moulin A, Rosolen SG, Martin S, Mavilio F, Amirjanians V, Stieger K, Lorenz B, Behar-Cohen F, Arsenijevic Y. Evaluation of tolerance to lentiviral LV-RPE65 gene therapy vector after subretinal delivery in nonhuman primates. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 28754419 DOI: 10.1016/J.Trsl.2017.06.012 |
0.514 |
|
| 2017 |
Lorenz B, Wegscheider E, Hamel C, Preising MN, Stieger K. Spatially Resolved Spectral Sensitivities as a Potential Read-out Parameter in Clinical Gene Therapeutic Trials. Ophthalmic Research. PMID 28697496 DOI: 10.1159/000477257 |
0.498 |
|
| 2017 |
Müller B, Wagner F, Lorenz B, Stieger K. Organotypic Cultures of Adult Mouse Retina: Morphologic Changes and Gene Expression. Investigative Ophthalmology & Visual Science. 58: 1930-1940. PMID 28384714 DOI: 10.1167/Iovs.16-20718 |
0.444 |
|
| 2017 |
Giers BC, Klein D, Mendes-Madeira A, Isiegas C, Lorenz B, Haverkamp S, Stieger K. Outer Plexiform Layer Structures Are Not Altered Following AAV-Mediated Gene Transfer in Healthy Rat Retina. Frontiers in Neurology. 8: 59. PMID 28280483 DOI: 10.3389/Fneur.2017.00059 |
0.591 |
|
| 2017 |
Stieger K. Novel gene based therapies for inherited retinal dystrophies in pediatric patients Acta Ophthalmologica. 95. DOI: 10.1111/J.1755-3768.2017.04414 |
0.431 |
|
| 2016 |
Yanik M, Müller B, Song F, Gall J, Wagner F, Wende W, Lorenz B, Stieger K. In vivo genome editing as a potential treatment strategy for inherited retinal dystrophies. Progress in Retinal and Eye Research. PMID 27623223 DOI: 10.1016/J.Preteyeres.2016.09.001 |
0.378 |
|
| 2016 |
Wimmer T, Lorenz B, Stieger K. Quantification of the vascular endothelial growth factor with a bioluminescence resonance energy transfer (BRET) based single molecule biosensor. Biosensors and Bioelectronics. 86: 609-615. PMID 27459244 DOI: 10.1016/J.Bios.2016.07.058 |
0.301 |
|
| 2016 |
Lorenz B, Stieger K, Jäger M, Mais C, Stieger S, Andrassi-Darida M. RETINAL VASCULAR DEVELOPMENT WITH 0.312 MG INTRAVITREAL BEVACIZUMAB TO TREAT SEVERE POSTERIOR RETINOPATHY OF PREMATURITY: A Longitudinal Fluorescein Angiographic Study. Retina (Philadelphia, Pa.). PMID 27454223 DOI: 10.1097/Iae.0000000000001126 |
0.336 |
|
| 2016 |
Bowl W, Stieger K, Bokun M, Schweinfurth S, Holve K, Andrassi-Darida M, Lorenz B. OCT-Based Macular Structure-Function Correlation in Dependence on Birth Weight and Gestational Age-the Giessen Long-Term ROP Study. Investigative Ophthalmology & Visual Science. 57: OCT235-41. PMID 27409477 DOI: 10.1167/Iovs.15-18843 |
0.364 |
|
| 2016 |
Stieger K, Trimborn L, Song F, Lorenz B, Yanik M. 137. Analysis of Cas9-FokI and TALE-MutH Endonuclease Activity and Toxicity as Key Elements in the Development of a Gene Therapeutic Approach to Treat XLRP Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)32946-X |
0.441 |
|
| 2015 |
Nelles M, Stieger K, Preising MN, Kruse J, Lorenz B. Shared decision-making, control preferences and psychological well-being in patients with RPE65 deficiency awaiting experimental gene therapy. Ophthalmic Research. 54: 96-102. PMID 26278420 DOI: 10.1159/000435887 |
0.515 |
|
| 2015 |
Slijkerman RW, Song F, Astuti GD, Huynen MA, van Wijk E, Stieger K, Collin RW. The pros and cons of vertebrate animal models for functional and therapeutic research on inherited retinal dystrophies. Progress in Retinal and Eye Research. PMID 25936606 DOI: 10.1016/J.Preteyeres.2015.04.004 |
0.498 |
|
| 2015 |
Lorenz B, Stieger K. Retinopathy of prematurity: recent developments in diagnosis and treatment Expert Review of Ophthalmology. 10: 167-182. DOI: 10.1586/17469899.2015.1007128 |
0.341 |
|
| 2015 |
Yanik M, Müller B, Stieger K. 346. Targeting the RPGR Gene for Gene Therapy with Highly Specific Nucleases Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33955-7 |
0.532 |
|
| 2014 |
Steck J, Blueml C, Kampmann S, Greene B, Maier RF, Arnhold S, Gerstner B, Stieger K, Lorenz B. Retinal vessel pathologies in a rat model of periventricular leukomalacia: a new model for retinopathy of prematurity? Investigative Ophthalmology & Visual Science. 56: 1830-41. PMID 25698709 DOI: 10.1167/Iovs.14-15262 |
0.392 |
|
| 2014 |
Le Guiner C, Stieger K, Toromanoff A, Guilbaud M, Mendes-Madeira A, Devaux M, Guigand L, Cherel Y, Moullier P, Rolling F, Adjali O. Transgene regulation using the tetracycline-inducible TetR-KRAB system after AAV-mediated gene transfer in rodents and nonhuman primates. Plos One. 9: e102538. PMID 25248159 DOI: 10.1371/Journal.Pone.0102538 |
0.731 |
|
| 2014 |
Klein D, Mendes-Madeira A, Schlegel P, Rolling F, Lorenz B, Haverkamp S, Stieger K. Immuno-histochemical analysis of rod and cone reaction to RPE65 deficiency in the inferior and superior canine retina. Plos One. 9: e86304. PMID 24466015 DOI: 10.1371/Journal.Pone.0086304 |
0.73 |
|
| 2014 |
Lorenz B, Steck J, Blueml C, Kampmann S, Gerstner B, Maier R, Stieger K. Retinal vessel pathologies in a rat model of periventricular leucomalazia Acta Ophthalmologica. 92: 0-0. DOI: 10.1111/J.1755-3768.2014.2652.X |
0.366 |
|
| 2014 |
Preising MN, Stieger K, Lorenz B. Genetik ophthalmologischer Erkrankungen. Teil 1: Genetische Grundlagen und Phänotypen Klinische Monatsblatter Fur Augenheilkunde. 4: 35-47. DOI: 10.1055/S-0033-1346932 |
0.305 |
|
| 2012 |
Pilch M, Wenner Y, Strohmayr E, Preising M, Friedburg C, Meyer Zu Bexten E, Lorenz B, Stieger K. Automated segmentation of retinal blood vessels in spectral domain optical coherence tomography scans. Biomedical Optics Express. 3: 1478-91. PMID 22808422 DOI: 10.1364/Boe.3.001478 |
0.304 |
|
| 2012 |
Lorenz B, Strohmayr E, Zahn S, Friedburg C, Kramer M, Preising M, Stieger K. Chromatic pupillometry dissects function of the three different light-sensitive retinal cell populations in RPE65 deficiency. Investigative Ophthalmology & Visual Science. 53: 5641-52. PMID 22807296 DOI: 10.1167/Iovs.12-9974 |
0.409 |
|
| 2011 |
Stieger K, Cronin T, Bennett J, Rolling F. Adeno-associated virus mediated gene therapy for retinal degenerative diseases. Methods in Molecular Biology (Clifton, N.J.). 807: 179-218. PMID 22034031 DOI: 10.1007/978-1-61779-370-7_8 |
0.798 |
|
| 2011 |
Hosch J, Lorenz B, Stieger K. RPGR: role in the photoreceptor cilium, human retinal disease, and gene therapy. Ophthalmic Genetics. 32: 1-11. PMID 21174525 DOI: 10.3109/13816810.2010.535889 |
0.513 |
|
| 2010 |
Stieger K, Lorenz B. Gene therapy for vision loss -- recent developments. Discovery Medicine. 10: 425-33. PMID 21122474 |
0.498 |
|
| 2010 |
Stieger K, Chauveau C, Rolling F. Preclinical studies on specific gene therapy for recessive retinal degenerative diseases. Current Gene Therapy. 10: 389-403. PMID 20718697 DOI: 10.2174/156652310793180689 |
0.802 |
|
| 2010 |
Lorenz B, Preising M, Stieger K. Retinal blinding disorders and gene therapy--molecular and clinical aspects. Current Gene Therapy. 10: 350-70. PMID 20712581 DOI: 10.2174/156652310793180698 |
0.497 |
|
| 2010 |
Stieger K. tgAAG76, an adeno-associated virus delivered gene therapy for the potential treatment of vision loss caused by RPE65 gene abnormalities. Current Opinion in Molecular Therapeutics. 12: 471-7. PMID 20677098 |
0.459 |
|
| 2009 |
Stieger K, Schroeder J, Provost N, Mendes-Madeira A, Belbellaa B, Meur GL, Weber M, Deschamps JY, Lorenz B, Moullier P, Rolling F. Detection of Intact rAAV Particles up to 6 Years After Successful Gene Transfer in the Retina of Dogs and Primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 516-523. PMID 28189016 DOI: 10.1038/mt.2008.283 |
0.795 |
|
| 2009 |
Stieger K, Belbellaa B, Le Guiner C, Moullier P, Rolling F. In vivo gene regulation using tetracycline-regulatable systems. Advanced Drug Delivery Reviews. 61: 527-41. PMID 19394373 DOI: 10.1016/J.Addr.2008.12.016 |
0.771 |
|
| 2009 |
Stieger K, Lhériteau E, Lhéariteau E, Moullier P, Rolling F. AAV-mediated gene therapy for retinal disorders in large animal models. Ilar Journal. 50: 206-24. PMID 19293463 DOI: 10.1093/Ilar.50.2.206 |
0.78 |
|
| 2009 |
Lhériteau E, Libeau L, Stieger K, Deschamps JY, Mendes-Madeira A, Provost N, Lemoine F, Mellersh C, Ellinwood NM, Cherel Y, Moullier P, Rolling F. The RPGRIP1-deficient dog, a promising canine model for gene therapy. Molecular Vision. 15: 349-61. PMID 19223988 |
0.701 |
|
| 2009 |
Stieger K, Schroeder J, Provost N, Mendes-Madeira A, Belbellaa B, Le Meur G, Weber M, Deschamps JY, Lorenz B, Moullier P, Rolling F. Detection of intact rAAV particles up to 6 years after successful gene transfer in the retina of dogs and primates. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 516-23. PMID 19107120 DOI: 10.1038/Mt.2008.283 |
0.759 |
|
| 2008 |
Stieger K, Lorenz B. Die Behandlung hereditärer Dystrophien und neovaskulärer Erkrankungen der Retina durch AAV-vermittelten Gentransfer Klinische Monatsblatter Fur Augenheilkunde. 225: 1009-1023. PMID 19085778 DOI: 10.1055/S-2008-1027607 |
0.633 |
|
| 2008 |
Stieger K, Colle MA, Dubreil L, Mendes-Madeira A, Weber M, Le Meur G, Deschamps JY, Provost N, Nivard D, Cherel Y, Moullier P, Rolling F. Subretinal delivery of recombinant AAV serotype 8 vector in dogs results in gene transfer to neurons in the brain. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 916-23. PMID 18388922 DOI: 10.1038/Mt.2008.41 |
0.796 |
|
| 2007 |
Le Guiner C, Stieger K, Snyder RO, Rolling F, Moullier P. Immune responses to gene product of inducible promoters. Current Gene Therapy. 7: 334-46. PMID 17979680 DOI: 10.2174/156652307782151461 |
0.712 |
|
| 2007 |
Stieger K, Mendes-Madeira A, Meur GL, Weber M, Deschamps JY, Nivard D, Provost N, Moullier P, Rolling F. Oral administration of doxycycline allows tight control of transgene expression: a key step towards gene therapy of retinal diseases. Gene Therapy. 14: 1668-73. PMID 17914405 DOI: 10.1038/sj.gt.3303034 |
0.756 |
|
| 2006 |
Rolling F, Le Meur G, Stieger K, Smith AJ, Weber M, Deschamps JY, Nivard D, Mendes-Madeira A, Provost N, Péréon Y, Cherel Y, Ali RR, Hamel C, Moullier P, Rolling F. Gene therapeutic prospects in early onset of severe retinal dystrophy: restoration of vision in RPE65 Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium. Bulletin Et Memoires De L'Academie Royale De Medecine De Belgique. 161: 497-508; discussion . PMID 17503728 |
0.82 |
|
| 2006 |
Le Meur G, Stieger K, Smith AJ, Weber M, Deschamps JY, Nivard D, Mendes-Madeira A, Provost N, Péréon Y, Cherel Y, Ali RR, Hamel C, Moullier P, Rolling F. Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium. Gene Therapy. 14: 292-303. PMID 17024105 DOI: 10.1038/Sj.Gt.3302861 |
0.772 |
|
| 2006 |
Stieger K, Le Meur G, Lasne F, Weber M, Deschamps JY, Nivard D, Mendes-Madeira A, Provost N, Martin L, Moullier P, Rolling F. Long-term doxycycline-regulated transgene expression in the retina of nonhuman primates following subretinal injection of recombinant AAV vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 967-75. PMID 16442848 DOI: 10.1016/J.Ymthe.2005.12.001 |
0.807 |
|
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