Harris A. Gelbard, M.D., Ph.D. - Publications

Affiliations: 
Center for Neural Development & Disease University of Rochester Medical Center, Rochester, NY, United States 
Area:
Neuroscience

120 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hammond JW, Bellizzi MJ, Ware C, Qiu WQ, Saminathan P, Li H, Luo S, Ma SA, Li Y, Gelbard HA. Complement-dependent synapse loss and microgliosis in a mouse model of multiple sclerosis. Brain, Behavior, and Immunity. PMID 32151684 DOI: 10.1016/j.bbi.2020.03.004  0.64
2019 Saminathan P, Kevadiya BD, Marker DF, Gendelman HE, Gorantla S, Gelbard HA. Broad Spectrum Mixed Lineage Kinase Type 3 Inhibition and HIV-1 Persistence in Macrophages. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 30617749 DOI: 10.1007/s11481-018-09829-8  0.56
2018 Bellizzi MJ, Hammond JW, Li H, Gantz Marker MA, Marker DF, Freeman RS, Gelbard HA. The Mixed-Lineage Kinase Inhibitor URMC-099 Protects Hippocampal Synapses in Experimental Autoimmune Encephalomyelitis. Eneuro. 5. PMID 30627663 DOI: 10.1523/ENEURO.0245-18.2018  0.64
2018 Hammond JW, Qiu WQ, Marker DF, Chamberlain JM, Greaves-Tunnell W, Bellizzi MJ, Lu SM, Gelbard HA. HIV Tat causes synapse loss in a mouse model of HIV-associated neurocognitive disorder that is independent of the classical complement cascade component C1q. Glia. PMID 30325063 DOI: 10.1002/glia.23511  0.64
2018 Thomas MB, Gnanadhas DP, Dash PK, Machhi J, Lin Z, McMillan J, Edagwa B, Gelbard H, Gendelman HE, Gorantla S. Modulating cellular autophagy for controlled antiretroviral drug release. Nanomedicine (London, England). PMID 30129397 DOI: 10.2217/nnm-2018-0224  0.56
2018 Kiyota T, Machhi J, Lu Y, Dyavarshetty B, Nemati M, Zhang G, Lee Mosley R, Gelbard HA, Gendelman HE. URMC-099 facilitates amyloid-β clearance in a murine model of Alzheimer's disease. Journal of Neuroinflammation. 15: 137. PMID 29729668 DOI: 10.1186/s12974-018-1172-y  0.56
2017 Gnanadhas DP, Dash PK, Sillman B, Bade AN, Lin Z, Palandri DL, Gautam N, Alnouti Y, Gelbard HA, McMillan J, Mosley RL, Edagwa B, Gendelman HE, Gorantla S. Autophagy facilitates macrophage depots of sustained-release nanoformulated antiretroviral drugs. The Journal of Clinical Investigation. PMID 28134625 DOI: 10.1172/JCI90025  0.56
2016 Dong W, Embury CM, Lu Y, Whitmire SM, Dyavarshetty B, Gelbard HA, Gendelman HE, Kiyota T. The mixed-lineage kinase 3 inhibitor URMC-099 facilitates microglial amyloid-β degradation. Journal of Neuroinflammation. 13: 184. PMID 27401058 DOI: 10.1186/s12974-016-0646-z  0.96
2016 Hammond JW, Lu SM, Gelbard HA. Corrigendum: Platelet Activating Factor Enhances Synaptic Vesicle Exocytosis Via PKC, Elevated Intracellular Calcium, and Modulation of Synapsin 1 Dynamics and Phosphorylation. Frontiers in Cellular Neuroscience. 10: 113. PMID 27199666 DOI: 10.3389/fncel.2016.00113  0.56
2016 Bellizzi MJ, Geathers JS, Allan KC, Gelbard HA. Platelet-Activating Factor Receptors Mediate Excitatory Postsynaptic Hippocampal Injury in Experimental Autoimmune Encephalomyelitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1336-46. PMID 26818520 DOI: 10.1523/JNEUROSCI.1171-15.2016  0.64
2016 Lu N, Silva JN, Gu Y, Wu H, Gelbard HA, Dewhurst S, Miao H. Capillary extraction by detecting polarity in circular profiles Iet Image Processing. 10: 339-348. DOI: 10.1049/iet-ipr.2015.0069  0.76
2015 Hammond JW, Lu SM, Gelbard HA. Platelet Activating Factor Enhances Synaptic Vesicle Exocytosis Via PKC, Elevated Intracellular Calcium, and Modulation of Synapsin 1 Dynamics and Phosphorylation. Frontiers in Cellular Neuroscience. 9: 505. PMID 26778968 DOI: 10.3389/fncel.2015.00505  0.56
2015 Zhang G, Guo D, Dash PK, Araínga M, Wiederin JL, Haverland NA, Knibbe-Hollinger J, Martinez-Skinner A, Ciborowski P, Goodfellow VS, Wysocki TA, Wysocki BJ, Poluektova LY, Liu XM, McMillan JM, ... ... Gelbard HA, et al. The Mixed Lineage Kinase-3 Inhibitor URMC-099 Improves Therapeutic Outcomes for Long-Acting Antiretroviral Therapy. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 26472049 DOI: 10.1016/j.nano.2015.09.009  0.56
2015 Puccini JM, Marker DF, Fitzgerald T, Barbieri J, Kim CS, Miller-Rhodes P, Lu SM, Dewhurst S, Gelbard HA. Leucine-rich repeat kinase 2 modulates neuroinflammation and neurotoxicity in models of human immunodeficiency virus 1-associated neurocognitive disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5271-83. PMID 25834052 DOI: 10.1523/JNEUROSCI.0650-14.2015  0.96
2014 Boska MD, Dash PK, Knibbe J, Epstein AA, Akhter SP, Fields N, High R, Makarov E, Bonasera S, Gelbard HA, Poluektova LY, Gendelman HE, Gorantla S. Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice. Molecular Neurodegeneration. 9: 58. PMID 25523827 DOI: 10.1186/1750-1326-9-58  0.56
2014 Rhoo KH, Granger M, Sur J, Feng C, Gelbard HA, Dewhurst S, Polesskaya O. Pharmacologic inhibition of MLK3 kinase activity blocks the in vitro migratory capacity of breast cancer cells but has no effect on breast cancer brain metastasis in a mouse xenograft model. Plos One. 9: e108487. PMID 25264786 DOI: 10.1371/journal.pone.0108487  0.96
2014 Gendelman HE, Gelbard HA. Adjunctive and long-acting nanoformulated antiretroviral therapies for HIV-associated neurocognitive disorders. Current Opinion in Hiv and Aids. 9: 585-90. PMID 25226025 DOI: 10.1097/COH.0000000000000111  0.96
2014 Guo D, Zhang G, Wysocki TA, Wysocki BJ, Gelbard HA, Liu XM, McMillan JM, Gendelman HE. Endosomal trafficking of nanoformulated antiretroviral therapy facilitates drug particle carriage and HIV clearance. Journal of Virology. 88: 9504-13. PMID 24920821 DOI: 10.1128/JVI.01557-14  0.96
2014 Dayawansa S, Wang EW, Liu W, Markman JD, Gelbard HA, Huang JH. Allotransplanted DRG neurons or Schwann cells affect functional recovery in a rodent model of sciatic nerve injury. Neurological Research. 36: 1020-7. PMID 24836462 DOI: 10.1179/1743132814Y.0000000386  0.96
2014 Kapetanovic S, Griner R, Zeldow B, Nichols S, Leister E, Gelbard HA, Miller TL, Hazra R, Mendez AJ, Malee K, Kammerer B, Williams PL. Biomarkers and neurodevelopment in perinatally HIV-infected or exposed youth: a structural equation model analysis. Aids (London, England). 28: 355-64. PMID 24670521 DOI: 10.1097/QAD.0000000000000072  0.96
2014 Polesskaya O, Wong C, Lebron L, Chamberlain JM, Gelbard HA, Goodfellow V, Kim M, Daiss JL, Dewhurst S. MLK3 regulates fMLP-stimulated neutrophil motility. Molecular Immunology. 58: 214-22. PMID 24389043 DOI: 10.1016/j.molimm.2013.11.016  0.96
2014 Marker DF, Lu SM, Gelbard HA. Human immunodeficiency virus Microglia in Health and Disease. 373-392. DOI: 10.1007/978-1-4939-1429-6_15  0.96
2013 Tremblay MÈ, Marker DF, Puccini JM, Muly EC, Lu SM, Gelbard HA. Ultrastructure of microglia-synapse interactions in the HIV-1 Tat-injected murine central nervous system. Communicative & Integrative Biology. 6: e27670. PMID 24563721 DOI: 10.4161/cib.27670  0.96
2013 Goodfellow VS, Loweth CJ, Ravula SB, Wiemann T, Nguyen T, Xu Y, Todd DE, Sheppard D, Pollack S, Polesskaya O, Marker DF, Dewhurst S, Gelbard HA. Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3. Journal of Medicinal Chemistry. 56: 8032-48. PMID 24044867 DOI: 10.1021/jm401094t  0.96
2013 Gelbard HA, Gendelman HE. Lipids and cognition make good bedfellows for neuroAIDS. Neurology. 81: 1480-1. PMID 24027058 DOI: 10.1212/WNL.0b013e3182a958ba  0.96
2013 Marker DF, Tremblay MÈ, Puccini JM, Barbieri J, Gantz Marker MA, Loweth CJ, Muly EC, Lu SM, Goodfellow VS, Dewhurst S, Gelbard HA. The new small-molecule mixed-lineage kinase 3 inhibitor URMC-099 is neuroprotective and anti-inflammatory in models of human immunodeficiency virus-associated neurocognitive disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 9998-10010. PMID 23761895 DOI: 10.1523/JNEUROSCI.0598-13.2013  0.96
2013 Ma Q, Gelbard HA, Maggirwar SB, Dewhurst S, Gendelman HE, Peterson DR, DiFrancesco R, Hochreiter JS, Morse GD, Schifitto G. Pharmacokinetic interactions of CEP-1347 and atazanavir in HIV-infected patients. Journal of Neurovirology. 19: 254-60. PMID 23737347 DOI: 10.1007/s13365-013-0172-z  0.96
2013 Lu N, Silva J, Gu Y, Gerber S, Wu H, Gelbard H, Dewhurst S, Miao H. Directional Histogram Ratio at Random Probes: A Local Thresholding Criterion for Capillary Images. Pattern Recognition. 46: 1933-1948. PMID 23525856 DOI: 10.1016/j.patcog.2013.01.011  0.96
2012 Marker DF, Puccini JM, Mockus TE, Barbieri J, Lu SM, Gelbard HA. LRRK2 kinase inhibition prevents pathological microglial phagocytosis in response to HIV-1 Tat protein. Journal of Neuroinflammation. 9: 261. PMID 23190742 DOI: 10.1186/1742-2094-9-261  0.96
2012 Dash PK, Gendelman HE, Roy U, Balkundi S, Alnouti Y, Mosley RL, Gelbard HA, McMillan J, Gorantla S, Poluektova LY. Long-acting nanoformulated antiretroviral therapy elicits potent antiretroviral and neuroprotective responses in HIV-1-infected humanized mice. Aids (London, England). 26: 2135-44. PMID 22824628 DOI: 10.1097/QAD.0b013e328357f5ad  0.96
2012 Lapin ZJ, Höppener C, Gelbard HA, Novotny L. Near-field quantification of complement receptor 1 (CR1/CD35) protein clustering in human erythrocytes. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 539-43. PMID 22374251 DOI: 10.1007/s11481-012-9346-3  0.96
2012 Liu W, Ren Y, Bossert A, Wang X, Dayawansa S, Tong J, He X, Smith DH, Gelbard HA, Huang JH. Allotransplanted neurons used to repair peripheral nerve injury do not elicit overt immunogenicity. Plos One. 7: e31675. PMID 22347502 DOI: 10.1371/journal.pone.0031675  0.96
2011 Lu SM, Tremblay MÈ, King IL, Qi J, Reynolds HM, Marker DF, Varrone JJ, Majewska AK, Dewhurst S, Gelbard HA. HIV-1 Tat-induced microgliosis and synaptic damage via interactions between peripheral and central myeloid cells. Plos One. 6: e23915. PMID 21912650 DOI: 10.1371/journal.pone.0023915  0.96
2011 Perry SW, Norman JP, Barbieri J, Brown EB, Gelbard HA. Mitochondrial membrane potential probes and the proton gradient: a practical usage guide. Biotechniques. 50: 98-115. PMID 21486251 DOI: 10.2144/000113610  0.96
2011 Dash PK, Gorantla S, Gendelman HE, Knibbe J, Casale GP, Makarov E, Epstein AA, Gelbard HA, Boska MD, Poluektova LY. Loss of neuronal integrity during progressive HIV-1 infection of humanized mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3148-57. PMID 21368026 DOI: 10.1523/JNEUROSCI.5473-10.2011  0.96
2011 Kasischke KA, Lambert EM, Panepento B, Sun A, Gelbard HA, Burgess RW, Foster TH, Nedergaard M. Two-photon NADH imaging exposes boundaries of oxygen diffusion in cortical vascular supply regions. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 68-81. PMID 20859293 DOI: 10.1038/jcbfm.2010.158  0.96
2010 Marker DF, Tremblay ME, Lu SM, Majewska AK, Gelbard HA. A thin-skull window technique for chronic two-photon in vivo imaging of murine microglia in models of neuroinflammation. Journal of Visualized Experiments : Jove. PMID 20972389 DOI: 10.3791/2059  0.96
2010 Polesskaya O, Cunningham LL, Francis SP, Luebke AE, Zhu X, Collins D, Vasilyeva ON, Sahler J, Desmet EA, Gelbard HA, Maggirwar SB, Walton JP, Frisina RD, Dewhurst S. Ablation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure. Hearing Research. 270: 21-7. PMID 20971179 DOI: 10.1016/j.heares.2010.10.008  0.96
2010 Perry SW, Barbieri J, Tong N, Polesskaya O, Pudasaini S, Stout A, Lu R, Kiebala M, Maggirwar SB, Gelbard HA. Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14153-64. PMID 20962236 DOI: 10.1523/JNEUROSCI.1042-10.2010  0.96
2010 Gelbard HA, Dewhurst S, Maggirwar SB, Kiebala M, Polesskaya O, Gendelman HE. Rebuilding synaptic architecture in HIV-1 associated neurocognitive disease: a therapeutic strategy based on modulation of mixed lineage kinase. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 7: 392-8. PMID 20880503 DOI: 10.1016/j.nurt.2010.08.001  0.96
2010 Kapetanovic S, Leister E, Nichols S, Miller T, Tassiopoulos K, Hazra R, Gelbard HA, Malee KM, Kammerer B, Mendez AJ, Williams PL. Relationships between markers of vascular dysfunction and neurodevelopmental outcomes in perinatally HIV-infected youth. Aids (London, England). 24: 1481-91. PMID 20539091 DOI: 10.1097/QAD.0b013e32833a241b  0.96
2010 Eggert D, Dash PK, Gorantla S, Dou H, Schifitto G, Maggirwar SB, Dewhurst S, Poluektova L, Gelbard HA, Gendelman HE. Neuroprotective activities of CEP-1347 in models of neuroAIDS. Journal of Immunology (Baltimore, Md. : 1950). 184: 746-56. PMID 19966207 DOI: 10.4049/jimmunol.0902962  0.96
2010 Bellizzi MJ, Gelbard HA. Infectious Agents in Neurodegenerative Disease Encyclopedia of Neuroscience. 125-129. DOI: 10.1016/B978-008045046-9.00503-9  0.96
2009 Eggert D, Dash PK, Serradji N, Dong CZ, Clayette P, Heymans F, Dou H, Gorantla S, Gelbard HA, Poluektova L, Gendelman HE. Development of a platelet-activating factor antagonist for HIV-1 associated neurocognitive disorders. Journal of Neuroimmunology. 213: 47-59. PMID 19541372 DOI: 10.1016/j.jneuroim.2009.06.002  0.96
2009 Schifitto G, Zhong J, Gill D, Peterson DR, Gaugh MD, Zhu T, Tivarus M, Cruttenden K, Maggirwar SB, Gendelman HE, Dewhurst S, Gelbard HA. Lithium therapy for human immunodeficiency virus type 1-associated neurocognitive impairment. Journal of Neurovirology. 15: 176-86. PMID 19306230 DOI: 10.1080/13550280902758973  0.96
2008 Norman JP, Perry SW, Reynolds HM, Kiebala M, De Mesy Bentley KL, Trejo M, Volsky DJ, Maggirwar SB, Dewhurst S, Masliah E, Gelbard HA. HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization. Plos One. 3: e3731. PMID 19009018 DOI: 10.1371/journal.pone.0003731  0.96
2008 DiCenzo R, Peterson DR, Cruttenden K, Mariuz P, Rezk NL, Hochreiter J, Gelbard H, Schifitto G. Effects of minocycline and valproic acid coadministration on atazanavir plasma concentrations in human immunodeficiency virus-infected adults receiving atazanavir-ritonavir. Antimicrobial Agents and Chemotherapy. 52: 3035-9. PMID 18573930 DOI: 10.1128/AAC.00194-08  0.96
2007 Lu SM, Tong N, Gelbard HA. The phospholipid mediator platelet-activating factor mediates striatal synaptic facilitation. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 2: 194-201. PMID 18040844 DOI: 10.1007/s11481-007-9064-4  0.96
2007 Dewhurst S, Maggirwar SB, Schifitto G, Gendelman HE, Gelbard HA. Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 2: 93-6. PMID 18040831 DOI: 10.1007/s11481-006-9051-1  0.96
2007 Sui Z, Sniderhan LF, Schifitto G, Phipps RP, Gelbard HA, Dewhurst S, Maggirwar SB. Functional synergy between CD40 ligand and HIV-1 Tat contributes to inflammation: implications in HIV type 1 dementia. Journal of Immunology (Baltimore, Md. : 1950). 178: 3226-36. PMID 17312171  0.96
2007 Norman JP, Perry SW, Kasischke KA, Volsky DJ, Gelbard HA. HIV-1 trans activator of transcription protein elicits mitochondrial hyperpolarization and respiratory deficit, with dysregulation of complex IV and nicotinamide adenine dinucleotide homeostasis in cortical neurons. Journal of Immunology (Baltimore, Md. : 1950). 178: 869-76. PMID 17202348  0.96
2006 Bellizzi MJ, Lu SM, Gelbard HA. Protecting the synapse: evidence for a rational strategy to treat HIV-1 associated neurologic disease. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 1: 20-31. PMID 18040788 DOI: 10.1007/s11481-005-9006-y  0.96
2006 Sui Z, Sniderhan LF, Fan S, Kazmierczak K, Reisinger E, Kovács AD, Potash MJ, Dewhurst S, Gelbard HA, Maggirwar SB. Human immunodeficiency virus-encoded Tat activates glycogen synthase kinase-3beta to antagonize nuclear factor-kappaB survival pathway in neurons. The European Journal of Neuroscience. 23: 2623-34. PMID 16817865 DOI: 10.1111/j.1460-9568.2006.04813.x  0.96
2006 Sui Z, Fan S, Sniderhan L, Reisinger E, Litzburg A, Schifitto G, Gelbard HA, Dewhurst S, Maggirwar SB. Inhibition of mixed lineage kinase 3 prevents HIV-1 Tat-mediated neurotoxicity and monocyte activation. Journal of Immunology (Baltimore, Md. : 1950). 177: 702-11. PMID 16785569  0.96
2006 Schifitto G, Peterson DR, Zhong J, Ni H, Cruttenden K, Gaugh M, Gendelman HE, Boska M, Gelbard H. Valproic acid adjunctive therapy for HIV-associated cognitive impairment: a first report. Neurology. 66: 919-21. PMID 16510768 DOI: 10.1212/01.wnl.0000204294.28189.03  0.96
2005 Bellizzi MJ, Lu SM, Masliah E, Gelbard HA. Synaptic activity becomes excitotoxic in neurons exposed to elevated levels of platelet-activating factor. The Journal of Clinical Investigation. 115: 3185-92. PMID 16276420 DOI: 10.1172/JCI25444  0.96
2005 Perry SW, Norman JP, Gelbard HA. Adjunctive therapies for HIV-1 associated neurologic disease. Neurotoxicity Research. 8: 161-6. PMID 16260393 DOI: 10.1007/BF03033827  0.96
2005 Dou H, Ellison B, Bradley J, Kasiyanov A, Poluektova LY, Xiong H, Maggirwar S, Dewhurst S, Gelbard HA, Gendelman HE. Neuroprotective mechanisms of lithium in murine human immunodeficiency virus-1 encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8375-85. PMID 16162919 DOI: 10.1523/JNEUROSCI.2164-05.2005  0.96
2005 Nelson JA, Dou H, Ellison B, Uberti M, Xiong H, Anderson E, Mellon M, Gelbard HA, Boska M, Gendelman HE. Coregistration of quantitative proton magnetic resonance spectroscopic imaging with neuropathological and neurophysiological analyses defines the extent of neuronal impairments in murine human immunodeficiency virus type-1 encephalitis. Journal of Neuroscience Research. 80: 562-75. PMID 15825192 DOI: 10.1002/jnr.20466  0.96
2005 Perry SW, Norman JP, Litzburg A, Zhang D, Dewhurst S, Gelbard HA. HIV-1 transactivator of transcription protein induces mitochondrial hyperpolarization and synaptic stress leading to apoptosis. Journal of Immunology (Baltimore, Md. : 1950). 174: 4333-44. PMID 15778398  0.96
2004 Nitkiewicz J, Chao W, Bentsman G, Li J, Kim SY, Choi SY, Grunig G, Gelbard H, Potash MJ, Volsky DJ. Productive infection of primary murine astrocytes, lymphocytes, and macrophages by human immunodeficiency virus type 1 in culture. Journal of Neurovirology. 10: 400-8. PMID 15765811 DOI: 10.1080/13550280490890097  0.96
2004 Dou H, Kingsley JD, Mosley RL, Gelbard HA, Gendelman HE. Neuroprotective strategies for HIV-1 associated dementia. Neurotoxicity Research. 6: 503-21. PMID 15639783 DOI: 10.1007/BF03033447  0.96
2004 DiCenzo R, Peterson D, Cruttenden K, Morse G, Riggs G, Gelbard H, Schifitto G. Effects of valproic acid coadministration on plasma efavirenz and lopinavir concentrations in human immunodeficiency virus-infected adults. Antimicrobial Agents and Chemotherapy. 48: 4328-31. PMID 15504860 DOI: 10.1128/AAC.48.11.4328-4331.2004  0.96
2004 Perry SW, Norman JP, Litzburg A, Gelbard HA. Antioxidants are required during the early critical period, but not later, for neuronal survival. Journal of Neuroscience Research. 78: 485-92. PMID 15389829 DOI: 10.1002/jnr.20272  0.96
2004 Ramirez SH, Fan S, Maguire CA, Perry S, Hardiek K, Ramkumar V, Gelbard HA, Dewhurst S, Maggirwar SB. Activation of adenosine A2A receptor protects sympathetic neurons against nerve growth factor withdrawal. Journal of Neuroscience Research. 77: 258-69. PMID 15211592 DOI: 10.1002/jnr.20150  0.96
2004 Latchney LR, Fallon MA, Culp DJ, Gelbard HA, Dewhurst S. Immunohistochemical assessment of fractalkine, inflammatory cells, and human herpesvirus 7 in human salivary glands. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 52: 671-81. PMID 15100244  0.96
2004 Wang Z, Trillo-Pazos G, Kim SY, Canki M, Morgello S, Sharer LR, Gelbard HA, Su ZZ, Kang DC, Brooks AI, Fisher PB, Volsky DJ. Effects of human immunodeficiency virus type 1 on astrocyte gene expression and function: potential role in neuropathogenesis. Journal of Neurovirology. 10: 25-32. PMID 14982736  0.96
2004 Guo H, Liu D, Gelbard H, Cheng T, Insalaco R, Fernández JA, Griffin JH, Zlokovic BV. Activated protein C prevents neuronal apoptosis via protease activated receptors 1 and 3. Neuron. 41: 563-72. PMID 14980205 DOI: 10.1016/S0896-6273(04)00019-4  0.96
2004 Gelbard HA. Synapses and Sisyphus: life without paraplegin. The Journal of Clinical Investigation. 113: 185-7. PMID 14722610 DOI: 10.1172/JCI20783  0.96
2003 Dou H, Birusingh K, Faraci J, Gorantla S, Poluektova LY, Maggirwar SB, Dewhurst S, Gelbard HA, Gendelman HE. Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9162-70. PMID 14534250  0.96
2003 Wang Z, Pekarskaya O, Bencheikh M, Chao W, Gelbard HA, Ghorpade A, Rothstein JD, Volsky DJ. Reduced expression of glutamate transporter EAAT2 and impaired glutamate transport in human primary astrocytes exposed to HIV-1 or gp120. Virology. 312: 60-73. PMID 12890621 DOI: 10.1016/S0042-6822(03)00181-8  0.96
2002 Perry SW, Dewhurst S, Bellizzi MJ, Gelbard HA. Tumor necrosis factor-alpha in normal and diseased brain: Conflicting effects via intraneuronal receptor crosstalk? Journal of Neurovirology. 8: 611-24. PMID 12476354 DOI: 10.1080/13550280290101021  0.96
2002 Diesing TS, Swindells S, Gelbard H, Gendelman HE. HIV-1-associated dementia: a basic science and clinical perspective. The Aids Reader. 12: 358-68. PMID 12229893  0.96
2001 Ramirez SH, Sanchez JF, Dimitri CA, Gelbard HA, Dewhurst S, Maggirwar SB. Neurotrophins prevent HIV Tat-induced neuronal apoptosis via a nuclear factor-kappaB (NF-kappaB)-dependent mechanism. Journal of Neurochemistry. 78: 874-89. PMID 11520908 DOI: 10.1046/j.1471-4159.2001.00467.x  0.96
2001 Tong N, Sanchez JF, Maggirwar SB, Ramirez SH, Guo H, Dewhurst S, Gelbard HA. Activation of glycogen synthase kinase 3 beta (GSK-3beta) by platelet activating factor mediates migration and cell death in cerebellar granule neurons. The European Journal of Neuroscience. 13: 1913-22. PMID 11403684 DOI: 10.1046/j.0953-816X.2001.01572.x  0.96
2001 Zhu Y, Gelbard HA, Roshal M, Pursell S, Jamieson BD, Planelles V. Comparison of cell cycle arrest, transactivation, and apoptosis induced by the simian immunodeficiency virus SIVagm and human immunodeficiency virus type 1 vpr genes. Journal of Virology. 75: 3791-801. PMID 11264368 DOI: 10.1128/JVI.75.8.3791-3801.2001  0.96
2000 Guo H, Tong N, Turner T, Epstein LG, McDermott MP, Kilgannon P, Gelbard HA. Release of the neuronal glycoprotein ICAM-5 in serum after hypoxic-ischemic injury. Annals of Neurology. 48: 590-602. PMID 11026442 DOI: 10.1002/1531-8249(200010)48:4<590::AID-ANA5>3.0.CO;2-7  0.96
2000 Maggirwar SB, Ramirez S, Tong N, Gelbard HA, Dewhurst S. Functional interplay between nuclear factor-kappaB and c-Jun integrated by coactivator p300 determines the survival of nerve growth factor-dependent PC12 cells. Journal of Neurochemistry. 74: 527-39. PMID 10646503 DOI: 10.1046/j.1471-4159.2000.740527.x  0.96
2000 Tong N, Perry SW, Zhang Q, James HJ, Guo H, Brooks A, Bal H, Kinnear SA, Fine S, Epstein LG, Dairaghi D, Schall TJ, Gendelman HE, Dewhurst S, Sharer LR, ... Gelbard HA, et al. Neuronal fractalkine expression in HIV-1 encephalitis: roles for macrophage recruitment and neuroprotection in the central nervous system. Journal of Immunology (Baltimore, Md. : 1950). 164: 1333-9. PMID 10640747  0.96
1999 Gelbard HA. Neuroprotective strategies for HIV-1-associated neurologic disease. Annals of the New York Academy of Sciences. 890: 312-3. PMID 10668436  0.96
1999 James HJ, Sharer LR, Zhang Q, Wang HG, Epstein LG, Reed JC, Gelbard HA. Expression of caspase-3 in brains from paediatric patients with HIV-1 encephalitis. Neuropathology and Applied Neurobiology. 25: 380-6. PMID 10564527 DOI: 10.1046/j.1365-2990.1999.00195.x  0.96
1999 Zheng J, Thylin MR, Ghorpade A, Xiong H, Persidsky Y, Cotter R, Niemann D, Che M, Zeng YC, Gelbard HA, Shepard RB, Swartz JM, Gendelman HE. Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia. Journal of Neuroimmunology. 98: 185-200. PMID 10430052 DOI: 10.1016/S0165-5728(99)00049-1  0.96
1999 Maggirwar SB, Tong N, Ramirez S, Gelbard HA, Dewhurst S. HIV-1 Tat-mediated activation of glycogen synthase kinase-3beta contributes to Tat-mediated neurotoxicity. Journal of Neurochemistry. 73: 578-86. PMID 10428053 DOI: 10.1046/j.1471-4159.1999.0730578.x  0.96
1999 Fine SM, Maggirwar SB, Elliott PR, Epstein LG, Gelbard HA, Dewhurst S. Proteasome blockers inhibit TNF-alpha release by lipopolysaccharide stimulated macrophages and microglia: implications for HIV-1 dementia. Journal of Neuroimmunology. 95: 55-64. PMID 10229115 DOI: 10.1016/S0165-5728(98)00267-7  0.96
1999 Epstein LG, Gelbard HA. HIV-1-induced neuronal injury in the developing brain. Journal of Leukocyte Biology. 65: 453-7. PMID 10204573  0.96
1999 Brooks AI, Chadwick CA, Gelbard HA, Cory-Slechta DA, Federoff HJ. Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss. Brain Research. 823: 1-10. PMID 10095006 DOI: 10.1016/S0006-8993(98)01192-5  0.96
1998 Hodge S, Novembre FJ, Whetter L, Gelbard HA, Dewhurst S. Induction of fas ligand expression by an acutely lethal simian immunodeficiency virus, SIVsmmPBj14. Virology. 252: 354-63. PMID 9878614 DOI: 10.1006/viro.1998.9477  0.96
1998 Deng SX, Panahian N, James H, Gelbard HA, Federoff HJ, Dewhurst S, Epstein LG. Luciferase: a sensitive and quantitative probe for blood-brain barrier disruption. Journal of Neuroscience Methods. 83: 159-64. PMID 9765129 DOI: 10.1016/S0165-0270(98)00077-6  0.96
1998 Teicher MH, Andersen SL, Campbell A, Gelbard HA, Baldessarini RJ. Progressive accumbens degeneration after neonatal striatal 6-hydroxydopamine in rats. Neuroscience Letters. 247: 99-102. PMID 9655602 DOI: 10.1016/S0304-3940(98)00281-X  0.96
1998 New DR, Maggirwar SB, Epstein LG, Dewhurst S, Gelbard HA. HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism. The Journal of Biological Chemistry. 273: 17852-8. PMID 9651389 DOI: 10.1074/jbc.273.28.17852  0.96
1998 Perry SW, Hamilton JA, Tjoelker LW, Dbaibo G, Dzenko KA, Epstein LG, Hannun Y, Whittaker JS, Dewhurst S, Gelbard HA. Platelet-activating factor receptor activation. An initiator step in HIV-1 neuropathogenesis. The Journal of Biological Chemistry. 273: 17660-4. PMID 9651362 DOI: 10.1074/jbc.273.28.17660  0.96
1997 Krajewski S, James HJ, Ross J, Blumberg BM, Epstein LG, Gendelman HE, Gummuluru S, Dewhurst S, Sharer LR, Reed JC, Gelbard HA. Expression of pro- and anti-apoptosis gene products in brains from paediatric patients with HIV-1 encephalitis. Neuropathology and Applied Neurobiology. 23: 242-53. PMID 9223134  0.96
1997 Perry SW, Epstein LG, Gelbard HA. Simultaneous in situ detection of apoptosis and necrosis in monolayer cultures by TUNEL and trypan blue staining. Biotechniques. 22: 1102-6. PMID 9187759  0.96
1997 Perry SW, Epstein LG, Gelbard HA. In situ trypan blue staining of monolayer cell cultures for permanent fixation and mounting. Biotechniques. 22: 1020-1, 1024. PMID 9187742  0.96
1997 Canki M, Potash MJ, Bentsman G, Chao W, Flynn T, Heinemann M, Gelbard H, Volsky DJ. Isolation and long-term culture of primary ocular human immunodeficiency virus type 1 isolates in primary astrocytes. Journal of Neurovirology. 3: 10-5. PMID 9147817  0.96
1997 New DR, Ma M, Epstein LG, Nath A, Gelbard HA. Human immunodeficiency virus type 1 Tat protein induces death by apoptosis in primary human neuron cultures. Journal of Neurovirology. 3: 168-73. PMID 9111179  0.96
1997 Gelbard HA, Boustany RM, Schor NF. Apoptosis in development and disease of the nervous system: II. Apoptosis in childhood neurologic disease. Pediatric Neurology. 16: 93-7. PMID 9090681 DOI: 10.1016/S0887-8994(96)00258-5  0.96
1997 Krajewski S, James HJ, Ross J, Blumberg BM, Epstein LG, Gendelman HE, Gummuluru S, Dewhurst S, Sharer LR, Reed JC, Gelbard HA. Expression of pro- and anti-apoptosis gene products in brains from paediatric patients with HIV-1 encephalitis Neuropathology and Applied Neurobiology. 23: 242-253. DOI: 10.1111/j.1365-2990.1997.tb01208.x  0.76
1996 Gummuluru S, Novembre FJ, Lewis M, Gelbard HA, Dewhurst S. Apoptosis correlates with immune activation in intestinal lymphoid tissue from macaques acutely infected by a highly enteropathic simian immunodeficiency virus, SIVsmmPBj14. Virology. 225: 21-32. PMID 8918530 DOI: 10.1006/viro.1996.0571  0.96
1996 Nottet HS, Flanagan EM, Flanagan CR, Gelbard HA, Gendelman HE, Reinhard JF. The regulation of quinolinic acid in human immunodeficiency virus-infected monocytes. Journal of Neurovirology. 2: 111-7. PMID 8799202  0.56
1996 Dewhurst S, Gelbard HA, Fine SM. Neuropathogenesis of AIDS. Molecular Medicine Today. 2: 16-23. PMID 8796847 DOI: 10.1016/1357-4310(96)88754-5  0.96
1996 Persidsky Y, Limoges J, McComb R, Bock P, Baldwin T, Tyor W, Patil A, Nottet HS, Epstein L, Gelbard H, Flanagan E, Reinhard J, Pirruccello SJ, Gendelman HE. Human immunodeficiency virus encephalitis in SCID mice. The American Journal of Pathology. 149: 1027-53. PMID 8780406  0.96
1996 Sharer LR, Saito Y, Da Cunha A, Ung PC, Gelbard HA, Epstein LG, Blumberg BM. In situ amplification and detection of HIV-1 DNA in fixed pediatric AIDS brain tissue. Human Pathology. 27: 614-7. PMID 8666375 DOI: 10.1016/S0046-8177(96)90172-0  0.96
1996 Fine SM, Angel RA, Perry SW, Epstein LG, Rothstein JD, Dewhurst S, Gelbard HA. Tumor necrosis factor alpha inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia. The Journal of Biological Chemistry. 271: 15303-6. PMID 8663435 DOI: 10.1074/jbc.271.26.15303  0.96
1995 Gelbard HA, Epstein LG. HIV-1 encephalopathy in children. Current Opinion in Pediatrics. 7: 655-62. PMID 8776015  0.96
1995 Dollard SC, James HJ, Sharer LR, Epstein LG, Gelbard HA, Dewhurst S. Activation of nuclear factor kappa B in brains from children with HIV-1 encephalitis. Neuropathology and Applied Neurobiology. 21: 518-28. PMID 8745241 DOI: 10.1111/j.1365-2990.1995.tb01098.x  0.96
1995 Talley AK, Dewhurst S, Perry SW, Dollard SC, Gummuluru S, Fine SM, New D, Epstein LG, Gendelman HE, Gelbard HA. Tumor necrosis factor alpha-induced apoptosis in human neuronal cells: protection by the antioxidant N-acetylcysteine and the genes bcl-2 and crmA. Molecular and Cellular Biology. 15: 2359-66. PMID 7739519 DOI: 10.1128/MCB.15.5.2359  0.96
1995 Gelbard HA, James HJ, Sharer LR, Perry SW, Saito Y, Kazee AM, Blumberg BM, Epstein LG. Apoptotic neurons in brains from paediatric patients with HIV-1 encephalitis and progressive encephalopathy. Neuropathology and Applied Neurobiology. 21: 208-17. PMID 7477729  0.96
1994 Gelbard HA, Nottet HS, Swindells S, Jett M, Dzenko KA, Genis P, White R, Wang L, Choi YB, Zhang D. Platelet-activating factor: a candidate human immunodeficiency virus type 1-induced neurotoxin. Journal of Virology. 68: 4628-35. PMID 8207837  0.96
1994 Gelbard HA, Applegate CD. Persistent increases in dopamine D2 receptor mRNA expression in basal ganglia following kindling. Epilepsy Research. 17: 23-9. PMID 8174522 DOI: 10.1016/0920-1211(94)90076-0  0.96
1994 Blumberg BM, Gelbard HA, Epstein LG. HIV-1 infection of the developing nervous system: central role of astrocytes in pathogenesis. Virus Research. 32: 253-67. PMID 8067056 DOI: 10.1016/0168-1702(94)90044-2  0.96
1993 Faedda GL, Tondo L, Teicher MH, Baldessarini RJ, Gelbard HA, Floris GF. Seasonal mood disorders. Patterns of seasonal recurrence in mania and depression. Archives of General Psychiatry. 50: 17-23. PMID 8422217 DOI: 10.1001/archpsyc.1993.01820130019004  0.96
1993 Ito Y, Teicher MH, Glod CA, Harper D, Magnus E, Gelbard HA. Increased prevalence of electrophysiological abnormalities in children with psychological, physical, and sexual abuse. The Journal of Neuropsychiatry and Clinical Neurosciences. 5: 401-8. PMID 8286938  0.96
1993 Teicher MH, Barber NI, Gelbard HA, Gallitano AL, Campbell A, Marsh E, Baldessarini RJ. Developmental differences in acute nigrostriatal and mesocorticolimbic system response to haloperidol. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 9: 147-56. PMID 8216697 DOI: 10.1038/npp.1993.53  0.96
1993 Gelbard HA, Dzenko KA, DiLoreto D, del Cerro C, del Cerro M, Epstein LG. Neurotoxic effects of tumor necrosis factor alpha in primary human neuronal cultures are mediated by activation of the glutamate AMPA receptor subtype: implications for AIDS neuropathogenesis. Developmental Neuroscience. 15: 417-22. PMID 7835247 DOI: 10.1159/000111367  0.96
1992 Genis P, Jett M, Bernton EW, Boyle T, Gelbard HA, Dzenko K, Keane RW, Resnick L, Mizrachi Y, Volsky DJ. Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophage-astroglia interactions: implications for the neuropathogenesis of HIV disease. The Journal of Experimental Medicine. 176: 1703-18. PMID 1460427  0.96
1991 Kieburtz KD, Epstein LG, Gelbard HA, Greenamyre JT. Excitotoxicity and dopaminergic dysfunction in the acquired immunodeficiency syndrome dementia complex. Therapeutic implications. Archives of Neurology. 48: 1281-4. PMID 1845034 DOI: 10.1001/archneur.1991.00530240087028  0.96
1991 Teicher MH, Gallitano AL, Gelbard HA, Evans HK, Marsh ER, Booth RG, Baldessarini RJ. Dopamine D1 autoreceptor function: possible expression in developing rat prefrontal cortex and striatum. Brain Research. Developmental Brain Research. 63: 229-35. PMID 1686425 DOI: 10.1016/0165-3806(91)90082-T  0.96
1990 Gelbard HA, Teicher MH, Baldessarini RJ, Gallitano A, Marsh ER, Zorc J, Faedda G. Dopamine D1 receptor development depends on endogenous dopamine. Brain Research. Developmental Brain Research. 56: 137-40. PMID 2149085 DOI: 10.1016/0165-3806(90)90173-V  0.96
1989 Gelbard HA, Teicher MH, Faedda G, Baldessarini RJ. Postnatal development of dopamine D1 and D2 receptor sites in rat striatum. Brain Research. Developmental Brain Research. 49: 123-30. PMID 2529061 DOI: 10.1016/0165-3806(89)90065-5  0.96
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