Anne Brunet, Ph.D. - Publications

Genetics Stanford University, Palo Alto, CA 
neural stem cells, neurogenesis, aging

133 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Xu L, Ramirez-Matias J, Hauptschein M, Sun ED, Lunger JC, Buckley MT, Brunet A. Restoration of neuronal progenitors by partial reprogramming in the aged neurogenic niche. Nature Aging. PMID 38553564 DOI: 10.1038/s43587-024-00594-3  0.589
2024 Reyes JM, Tovy A, Zhang L, Bortoletto AS, Rosas C, Chen CW, Waldvogel SM, Guzman AG, Aguilar R, Gupta S, Liu L, Buckley MT, Patel KR, Marcogliese AN, Li Y, ... ... Brunet A, et al. Hematologic DNMT3A reduction and high-fat diet synergize to promote weight gain and tissue inflammation. Iscience. 27: 109122. PMID 38414863 DOI: 10.1016/j.isci.2024.109122  0.571
2023 Yeo RW, Zhou OY, Zhong BL, Sun ED, Navarro Negredo P, Nair S, Sharmin M, Ruetz TJ, Wilson M, Kundaje A, Dunn AR, Brunet A. Chromatin accessibility dynamics of neurogenic niche cells reveal defects in neural stem cell adhesion and migration during aging. Nature Aging. 3: 866-893. PMID 37443352 DOI: 10.1038/s43587-023-00449-3  0.824
2023 Bedbrook CN, Nath RD, Nagvekar R, Deisseroth K, Brunet A. Rapid and precise genome engineering in a naturally short-lived vertebrate. Elife. 12. PMID 37191291 DOI: 10.7554/eLife.80639  0.798
2023 Reeves GA, Singh PP, Brunet A. Chromatin Accessibility Profiling and Data Analysis using ATAC-seq in . Cold Spring Harbor Protocols. PMID 37100469 DOI: 10.1101/pdb.prot107747  0.738
2023 Liu L, Kim S, Buckley MT, Reyes JM, Kang J, Tian L, Wang M, Lieu A, Mao M, Rodriguez-Mateo C, Ishak HD, Jeong M, Wu JC, Goodell MA, Brunet A, et al. Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging. Cell Stem Cell. PMID 37080206 DOI: 10.1016/j.stem.2023.03.016  0.552
2023 Nath RD, Bedbrook CN, Nagvekar R, Brunet A. Husbandry of the African Turquoise Killifish . Cold Spring Harbor Protocols. PMID 36863854 DOI: 10.1101/pdb.prot107738  0.774
2023 Bedbrook CN, Nath RD, Barajas R, Brunet A. Life Span Assessment in the African Turquoise Killifish . Cold Spring Harbor Protocols. PMID 36863852 DOI: 10.1101/pdb.prot107917  0.763
2022 Buckley MT, Sun ED, George BM, Liu L, Schaum N, Xu L, Reyes JM, Goodell MA, Weissman IL, Wyss-Coray T, Rando TA, Brunet A. Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain. Nature Aging. 3: 121-137. PMID 37118510 DOI: 10.1038/s43587-022-00335-4  0.803
2022 Booth LN, Shi C, Tantilert C, Yeo RW, Miklas JW, Hebestreit K, Hollenhorst CN, Maures TJ, Buckley MT, Murphy CT, Brunet A. Males induce premature demise of the opposite sex by multifaceted strategies. Nature Aging. 2: 809-823. PMID 37118502 DOI: 10.1038/s43587-022-00276-y  0.767
2022 McKay A, Costa EK, Chen J, Hu CK, Chen X, Bedbrook CN, Khondker RC, Thielvoldt M, Priya Singh P, Wyss-Coray T, Brunet A. An automated feeding system for the African killifish reveals effects of dietary restriction on lifespan and allows scalable assessment of associative learning. Elife. 11. PMID 36354233 DOI: 10.7554/eLife.69008  0.773
2020 Wang W, Hu CK, Zeng A, Alegre D, Hu D, Gotting K, Ortega Granillo A, Wang Y, Robb S, Schnittker R, Zhang S, Alegre D, Li H, Ross E, Zhang N, ... Brunet A, et al. Changes in regeneration-responsive enhancers shape regenerative capacities in vertebrates. Science (New York, N.Y.). 369. PMID 32883834 DOI: 10.1126/Science.Aaz3090  0.581
2020 Yan X, Zhao X, Zhou Z, McKay A, Brunet A, Zare RN. Cell-Type-Specific Metabolic Profiling Achieved by Combining Desorption Electrospray Ionization Mass Spectrometry Imaging and Immunofluorescence Staining. Analytical Chemistry. PMID 32880432 DOI: 10.1021/Acs.Analchem.0C02519  0.781
2020 Navarro Negredo P, Yeo RW, Brunet A. Aging and Rejuvenation of Neural Stem Cells and Their Niches. Cell Stem Cell. PMID 32726579 DOI: 10.1016/J.Stem.2020.07.002  0.808
2020 Brunet A. Old and new models for the study of human ageing. Nature Reviews. Molecular Cell Biology. PMID 32572179 DOI: 10.1038/S41580-020-0266-4  0.352
2020 Vonk WIM, Rainbolt TK, Dolan PT, Webb AE, Brunet A, Frydman J. Differentiation Drives Widespread Rewiring of the Neural Stem Cell Chaperone Network. Molecular Cell. PMID 32268122 DOI: 10.1016/J.Molcel.2020.03.009  0.677
2020 Hu CK, Wang W, Brind'Amour J, Singh PP, Reeves GA, Lorincz MC, Alvarado AS, Brunet A. Vertebrate diapause preserves organisms long term through Polycomb complex members. Science (New York, N.Y.). 367: 870-874. PMID 32079766 DOI: 10.1126/Science.Aaw2601  0.792
2020 Miklas JW, Brunet A. Support cells in the brain promote longevity. Science (New York, N.Y.). 367: 365-366. PMID 31974234 DOI: 10.1126/Science.Aba4474  0.304
2020 Ahadi S, Zhou W, Schüssler-Fiorenza Rose SM, Sailani MR, Contrepois K, Avina M, Ashland M, Brunet A, Snyder M. Personal aging markers and ageotypes revealed by deep longitudinal profiling. Nature Medicine. 26: 83-90. PMID 31932806 DOI: 10.1038/S41591-019-0719-5  0.339
2019 Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, Srinivasan R, Li X, Devarajan K, Prélot L, Ang CE, Shibuya Y, Benayoun BA, Chang ALS, Wernig M, ... ... Brunet A, et al. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. Nature. 574: 553-558. PMID 31645721 DOI: 10.1038/S41586-019-1658-5  0.783
2019 Booth LN, Maures TJ, Yeo RW, Tantilert C, Brunet A. Self-sperm induce resistance to the detrimental effects of sexual encounters with males in hermaphroditic nematodes. Elife. 8. PMID 31282863 DOI: 10.7554/Elife.46418  0.765
2019 Dulken BW, Buckley MT, Navarro Negredo P, Saligrama N, Cayrol R, Leeman DS, George BM, Boutet SC, Hebestreit K, Pluvinage JV, Wyss-Coray T, Weissman IL, Vogel H, Davis MM, Brunet A. Single-cell analysis reveals T cell infiltration in old neurogenic niches. Nature. PMID 31270459 DOI: 10.1038/S41586-019-1362-5  0.792
2019 Singh PP, Demmitt BA, Nath RD, Brunet A. The Genetics of Aging: A Vertebrate Perspective. Cell. 177: 200-220. PMID 30901541 DOI: 10.1016/J.Cell.2019.02.038  0.8
2019 Benayoun BA, Pollina EA, Singh PP, Mahmoudi S, Harel I, Casey KM, Dulken BW, Kundaje A, Brunet A. Remodeling of epigenome and transcriptome landscapes with aging in mice reveals widespread induction of inflammatory responses. Genome Research. PMID 30858345 DOI: 10.1101/Gr.240093.118  0.798
2019 Mahmoudi S, Xu L, Brunet A. Turning back time with emerging rejuvenation strategies. Nature Cell Biology. 21: 32-43. PMID 30602763 DOI: 10.1038/S41556-018-0206-0  0.808
2019 Booth LN, Maures TJ, Yeo RW, Tantilert C, Brunet A. Author response: Self-sperm induce resistance to the detrimental effects of sexual encounters with males in hermaphroditic nematodes Elife. DOI: 10.7554/Elife.46418.029  0.746
2019 Brunet A. EPIGENETIC AND METABOLIC REGULATION OF AGING Innovation in Aging. 3: S234-S234. DOI: 10.1093/Geroni/Igz038.871  0.411
2018 Contrepois K, Mahmoudi S, Ubhi BK, Papsdorf K, Hornburg D, Brunet A, Snyder M. Cross-Platform Comparison of Untargeted and Targeted Lipidomics Approaches on Aging Mouse Plasma. Scientific Reports. 8: 17747. PMID 30532037 DOI: 10.1038/S41598-018-35807-4  0.691
2018 Papsdorf K, Brunet A. Linking Lipid Metabolism to Chromatin Regulation in Aging. Trends in Cell Biology. PMID 30316636 DOI: 10.1016/J.Tcb.2018.09.004  0.336
2018 Lim JP, Fehlauer H, Das A, Saro G, Glauser DA, Brunet A, Goodman MB. gLoss of CaMKI function disrupts salt aversive learning in . The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29875264 DOI: 10.1523/Jneurosci.1611-17.2018  0.642
2018 Leeman DS, Hebestreit K, Ruetz T, Webb AE, McKay A, Pollina EA, Dulken BW, Zhao X, Yeo RW, Ho TT, Mahmoudi S, Devarajan K, Passegué E, Rando TA, Frydman J, ... Brunet A, et al. Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging. Science (New York, N.Y.). 359: 1277-1283. PMID 29590078 DOI: 10.1126/Science.Aag3048  0.765
2018 Hu CK, Brunet A. The African turquoise killifish: A research organism to study vertebrate aging and diapause. Aging Cell. e12757. PMID 29573324 DOI: 10.1111/Acel.12757  0.601
2018 Wagner JT, Singh PP, Romney AL, Riggs CL, Minx P, Woll SC, Roush J, Warren WC, Brunet A, Podrabsky JE. The genome of Austrofundulus limnaeus offers insights into extreme vertebrate stress tolerance and embryonic development. Bmc Genomics. 19: 155. PMID 29463212 DOI: 10.1186/S12864-018-4539-7  0.672
2018 Dulken BW, Brunet A. Same path, different beginnings. Nature Neuroscience. 21: 159-160. PMID 29371659 DOI: 10.1038/S41593-017-0063-3  0.797
2018 Brunet A. The African Killifish: A New Vertebrate Model To Study Aging And Age-Related Diseases Innovation in Aging. 2: 625-626. DOI: 10.1093/Geroni/Igy023.2332  0.319
2018 Benayoun B, Pollina EA, Brunet A. EPIGENOMICS OF AGING IN VERTEBRATES Innovation in Aging. 2: 625-625. DOI: 10.1093/Geroni/Igy023.2330  0.792
2017 Daugherty AC, Yeo RW, Buenrostro JD, Greenleaf WJ, Kundaje A, Brunet A. Chromatin accessibility dynamics reveal novel functional enhancers in C. elegans. Genome Research. PMID 29141961 DOI: 10.1101/Gr.226233.117  0.796
2017 Tan MH, Li Q, Shanmugam R, Piskol R, Kohler J, Young AN, Liu KI, Zhang R, Ramaswami G, Ariyoshi K, Gupte A, Keegan LP, George CX, Ramu A, Huang N, ... ... Brunet A, et al. Dynamic landscape and regulation of RNA editing in mammals. Nature. 550: 249-254. PMID 29022589 DOI: 10.1038/Nature24041  0.78
2017 Russell JJ, Theriot JA, Sood P, Marshall WF, Landweber LF, Fritz-Laylin L, Polka JK, Oliferenko S, Gerbich T, Gladfelter A, Umen J, Bezanilla M, Lancaster MA, He S, Gibson MC, ... ... Brunet A, et al. Non-model model organisms. Bmc Biology. 15: 55. PMID 28662661 DOI: 10.1186/S12915-017-0391-5  0.52
2017 Theret M, Gsaier L, Schaffer B, Juban G, Ben Larbi S, Weiss-Gayet M, Bultot L, Caterina C, Foretz M, Desplanches D, Sanz P, Zang Z, Yang L, Vial G, Viollet B, ... ... Brunet A, et al. AMPKα1-LDH pathway regulates muscle stem cell self-renewal by controlling metabolic homeostasis. The Embo Journal. PMID 28515121 DOI: 10.15252/Embj.201695273  0.803
2017 Kao AW, McKay A, Singh PP, Brunet A, Huang EJ. Progranulin, lysosomal regulation and neurodegenerative disease. Nature Reviews. Neuroscience. PMID 28435163 DOI: 10.1038/Nrn.2017.36  0.78
2017 Han S, Schroeder EA, Silva-García CG, Hebestreit K, Mair WB, Brunet A. Mono-unsaturated fatty acids link H3K4me3 modifiers to C. elegans lifespan. Nature. PMID 28379943 DOI: 10.1038/Nature21686  0.796
2017 Brunet A, Rando TA. Interaction between epigenetic and metabolism in aging stem cells. Current Opinion in Cell Biology. 45: 1-7. PMID 28129586 DOI: 10.1016/J.Ceb.2016.12.009  0.427
2017 Dulken BW, Leeman DS, Boutet SC, Hebestreit K, Brunet A. Single-Cell Transcriptomic Analysis Defines Heterogeneity and Transcriptional Dynamics in the Adult Neural Stem Cell Lineage. Cell Reports. 18: 777-790. PMID 28099854 DOI: 10.1016/J.Celrep.2016.12.060  0.799
2016 Mahmoudi S, Brunet A. Bursts of Reprogramming: A Path to Extend Lifespan? Cell. 167: 1672-1674. PMID 27984716 DOI: 10.1016/J.Cell.2016.11.050  0.724
2016 Harel I, Valenzano DR, Brunet A. Efficient genome engineering approaches for the short-lived African turquoise killifish. Nature Protocols. 11: 2010-2028. PMID 27658015 DOI: 10.1038/Nprot.2016.103  0.789
2016 Ahlenius H, Chanda S, Webb AE, Yousif I, Karmazin J, Prusiner SB, Brunet A, Südhof TC, Wernig M. FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice. Proceedings of the National Academy of Sciences of the United States of America. 113: 8514-9. PMID 27402759 DOI: 10.1073/Pnas.1607079113  0.702
2016 Booth LN, Brunet A. The Aging Epigenome. Molecular Cell. 62: 728-744. PMID 27259204 DOI: 10.1016/J.Molcel.2016.05.013  0.793
2016 Webb AE, Kundaje A, Brunet A. Characterization of the direct targets of FOXO transcription factors throughout evolution. Aging Cell. PMID 27061590 DOI: 10.1111/Acel.12479  0.698
2016 Yeo R, Brunet A. Deconstructing Dietary Restriction: A Case for Systems Approaches in Aging. Cell Metabolism. 23: 395-396. PMID 26959179 DOI: 10.1016/J.Cmet.2016.02.018  0.792
2015 Benayoun BA, Pollina EA, Ucar D, Mahmoudi S, Karra K, Wong ED, Devarajan K, Daugherty AC, Kundaje AB, Mancini E, Hitz BC, Gupta R, Rando TA, Baker JC, Snyder MP, ... ... Brunet A, et al. H3K4me3 Breadth Is Linked to Cell Identity and Transcriptional Consistency. Cell. 163: 1281-1286. PMID 28930648 DOI: 10.1016/j.cell.2015.10.051  0.791
2015 Harel I, Brunet A. The African Turquoise Killifish: A Model for Exploring Vertebrate Aging and Diseases in the Fast Lane. Cold Spring Harbor Symposia On Quantitative Biology. PMID 26642856 DOI: 10.1101/Sqb.2015.80.027524  0.781
2015 Valenzano DR, Benayoun BA, Singh PP, Zhang E, Etter PD, Hu CK, Clément-Ziza M, Willemsen D, Cui R, Harel I, Machado BE, Yee MC, Sharp SC, Bustamante CD, Beyer A, ... ... Brunet A, et al. The African Turquoise Killifish Genome Provides Insights into Evolution and Genetic Architecture of Lifespan. Cell. 163: 1539-54. PMID 26638078 DOI: 10.1016/J.Cell.2015.11.008  0.778
2015 Hardie DG, Schaffer BE, Brunet A. AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs. Trends in Cell Biology. PMID 26616193 DOI: 10.1016/J.Tcb.2015.10.013  0.794
2015 Pech MF, Garbuzov A, Hasegawa K, Sukhwani M, Zhang RJ, Benayoun BA, Brockman SA, Lin S, Brunet A, Orwig KE, Artandi SE. High telomerase is a hallmark of undifferentiated spermatogonia and is required for maintenance of male germline stem cells. Genes & Development. PMID 26584619 DOI: 10.1101/Gad.271783.115  0.673
2015 Schaffer BE, Levin RS, Hertz NT, Maures TJ, Schoof ML, Hollstein PE, Benayoun BA, Banko MR, Shaw RJ, Shokat KM, Brunet A. Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction. Cell Metabolism. 22: 907-21. PMID 26456332 DOI: 10.1016/J.Cmet.2015.09.009  0.785
2015 Benayoun BA, Pollina EA, Brunet A. Epigenetic regulation of ageing: linking environmental inputs to genomic stability. Nature Reviews. Molecular Cell Biology. 16: 593-610. PMID 26373265 DOI: 10.1038/Nrm4048  0.808
2015 Booth LN, Brunet A. Shockingly Early: Chromatin-Mediated Loss of the Heat Shock Response. Molecular Cell. 59: 515-6. PMID 26295957 DOI: 10.1016/J.Molcel.2015.08.004  0.774
2015 Li YH, Luo J, Mosley YC, Hedrick VE, Paul LN, Chang J, Zhang G, Wang YK, Banko MR, Brunet A, Kuang S, Wu JL, Chang CJ, Scott MP, Yang JY. AMP-Activated Protein Kinase Directly Phosphorylates and Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Medulloblastoma. Cell Reports. PMID 26190112 DOI: 10.1016/J.Celrep.2015.06.054  0.803
2015 Dulken B, Brunet A. Stem Cell Aging and Sex: Are We Missing Something? Cell Stem Cell. 16: 588-90. PMID 26046758 DOI: 10.1016/J.Stem.2015.05.006  0.811
2015 Harel I, Benayoun BA, Machado B, Singh PP, Hu CK, Pech MF, Valenzano DR, Zhang E, Sharp SC, Artandi SE, Brunet A. A platform for rapid exploration of aging and diseases in a naturally short-lived vertebrate. Cell. 160: 1013-26. PMID 25684364 DOI: 10.1016/J.Cell.2015.01.038  0.791
2015 Han S, Brunet A. Cell biology. Lysosomal lipid lengthens life span. Science (New York, N.Y.). 347: 32-3. PMID 25554778 DOI: 10.1126/Science.Aaa4565  0.567
2015 Kareta MS, Gorges LL, Hafeez S, Benayoun BA, Marro S, Zmoos AF, Cecchini MJ, Spacek D, Batista LF, O'Brien M, Ng YH, Ang CE, Vaka D, Artandi SE, Dick FA, ... Brunet A, et al. Inhibition of pluripotency networks by the Rb tumor suppressor restricts reprogramming and tumorigenesis. Cell Stem Cell. 16: 39-50. PMID 25467916 DOI: 10.1016/J.Stem.2014.10.019  0.672
2015 Pech M, Garbuzov A, Sukhwani M, Benayoun B, Lin S, Brunet A, Orwig K, Artandi SE. Abstract 980: Encoding immortality: Transcriptional control of telomerase in stem cells in vivo Cancer Research. 75: 980-980. DOI: 10.1158/1538-7445.Am2015-980  0.688
2014 Kennedy BK, Berger SL, Brunet A, Campisi J, Cuervo AM, Epel ES, Franceschi C, Lithgow GJ, Morimoto RI, Pessin JE, Rando TA, Richardson A, Schadt EE, Wyss-Coray T, Sierra F. Geroscience: linking aging to chronic disease. Cell. 159: 709-13. PMID 25417146 DOI: 10.1016/J.Cell.2014.10.039  0.542
2014 Benayoun BA, Pollina EA, Ucar D, Mahmoudi S, Karra K, Wong ED, Devarajan K, Daugherty AC, Kundaje AB, Mancini E, Hitz BC, Gupta R, Rando TA, Baker JC, Snyder MP, ... ... Brunet A, et al. H3K4me3 breadth is linked to cell identity and transcriptional consistency. Cell. 158: 673-88. PMID 25083876 DOI: 10.1016/J.Cell.2014.06.027  0.791
2014 Brunet A, Berger SL. Epigenetics of aging and aging-related disease. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 69: S17-20. PMID 24833581 DOI: 10.1093/Gerona/Glu042  0.377
2014 Gopinath SD, Webb AE, Brunet A, Rando TA. FOXO3 promotes quiescence in adult muscle stem cells during the process of self-renewal. Stem Cell Reports. 2: 414-26. PMID 24749067 DOI: 10.1016/J.Stemcr.2014.02.002  0.67
2014 Webb AE, Brunet A. FOXO transcription factors: key regulators of cellular quality control. Trends in Biochemical Sciences. 39: 159-69. PMID 24630600 DOI: 10.1016/J.Tibs.2014.02.003  0.695
2014 Leeman DS, Brunet A. Stem cells: Sex specificity in the blood. Nature. 505: 488-90. PMID 24451537 DOI: 10.1038/505488A  0.783
2014 Maures TJ, Booth LN, Benayoun BA, Izrayelit Y, Schroeder FC, Brunet A. Males shorten the life span of C. elegans hermaphrodites via secreted compounds. Science (New York, N.Y.). 343: 541-4. PMID 24292626 DOI: 10.1126/Science.1244160  0.776
2014 Brunet A, Mahmoudi S, Mancini E, Rafalski VA, Webb AE. Longevity Pathways in Mammalian Stem Cells Annual Review of Gerontology and Geriatrics. 34: 1-40. DOI: 10.1891/0198-8794.34.1  0.793
2014 Passegue E, Teitell M, Ding S, Rando T, Belmonte JCI, Ramalho-Santos M, Terzic A, Brunet A, Chandel NS, Bonnet D, Jasper H. Stem cell energetics Cell Metabolism. 20: 922-925. DOI: 10.1016/J.Cmet.2014.11.007  0.363
2013 Wapinski OL, Vierbuchen T, Qu K, Lee QY, Chanda S, Fuentes DR, Giresi PG, Ng YH, Marro S, Neff NF, Drechsel D, Martynoga B, Castro DS, Webb AE, Südhof TC, ... Brunet A, et al. Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. Cell. 155: 621-35. PMID 24243019 DOI: 10.1016/J.Cell.2013.09.028  0.696
2013 Webb AE, Pollina EA, Vierbuchen T, Urbán N, Ucar D, Leeman DS, Martynoga B, Sewak M, Rando TA, Guillemot F, Wernig M, Brunet A. FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis. Cell Reports. 4: 477-91. PMID 23891001 DOI: 10.1016/J.Celrep.2013.06.035  0.812
2013 Liu L, Cheung TH, Charville GW, Hurgo BM, Leavitt T, Shih J, Brunet A, Rando TA. Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging. Cell Reports. 4: 189-204. PMID 23810552 DOI: 10.1016/J.Celrep.2013.05.043  0.338
2013 Rafalski VA, Ho PP, Brett JO, Ucar D, Dugas JC, Pollina EA, Chow LM, Ibrahim A, Baker SJ, Barres BA, Steinman L, Brunet A. Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain. Nature Cell Biology. 15: 614-24. PMID 23644469 DOI: 10.1038/Ncb2735  0.793
2013 Webb AE, Brunet A. FOXO flips the longevity SWItch. Nature Cell Biology. 15: 444-6. PMID 23636422 DOI: 10.1038/Ncb2749  0.676
2013 Lim JP, Brunet A. Bridging the transgenerational gap with epigenetic memory. Trends in Genetics : Tig. 29: 176-86. PMID 23410786 DOI: 10.1016/J.Tig.2012.12.008  0.51
2012 Benayoun BA, Brunet A. Epigenetic memory of longevity in Caenorhabditis elegans. Worm. 1: 77-81. PMID 24058828 DOI: 10.4161/worm.19157  0.612
2012 Rafalski VA, Mancini E, Brunet A. Energy metabolism and energy-sensing pathways in mammalian embryonic and adult stem cell fate. Journal of Cell Science. 125: 5597-608. PMID 23420198 DOI: 10.1242/Jcs.114827  0.806
2012 Salih DA, Rashid AJ, Colas D, de la Torre-Ubieta L, Zhu RP, Morgan AA, Santo EE, Ucar D, Devarajan K, Cole CJ, Madison DV, Shamloo M, Butte AJ, Bonni A, Josselyn SA, ... Brunet A, et al. FoxO6 regulates memory consolidation and synaptic function. Genes & Development. 26: 2780-801. PMID 23222102 DOI: 10.1101/Gad.208926.112  0.789
2012 Mahmoudi S, Brunet A. Aging and reprogramming: a two-way street. Current Opinion in Cell Biology. 24: 744-56. PMID 23146768 DOI: 10.1016/J.Ceb.2012.10.004  0.748
2012 Calnan DR, Webb AE, White JL, Stowe TR, Goswami T, Shi X, Espejo A, Bedford MT, Gozani O, Gygi SP, Brunet A. Methylation by Set9 modulates FoxO3 stability and transcriptional activity. Aging. 4: 462-79. PMID 22820736  0.652
2012 Brunet A. [Aging and the control of the insulin-FOXO signaling pathway]. Mã©Decine Sciences : M/S. 28: 316-20. PMID 22480657 DOI: 10.1051/Medsci/2012283021  0.416
2012 Han S, Brunet A. Histone methylation makes its mark on longevity. Trends in Cell Biology. 22: 42-9. PMID 22177962 DOI: 10.1016/J.Tcb.2011.11.001  0.554
2011 Valenzano DR, Sharp S, Brunet A. Transposon-Mediated Transgenesis in the Short-Lived African Killifish Nothobranchius furzeri, a Vertebrate Model for Aging. G3 (Bethesda, Md.). 1: 531-8. PMID 22384364 DOI: 10.1534/G3.111.001271  0.686
2011 Banko MR, Allen JJ, Schaffer BE, Wilker EW, Tsou P, White JL, Villén J, Wang B, Kim SR, Sakamoto K, Gygi SP, Cantley LC, Yaffe MB, Shokat KM, Brunet A. Chemical genetic screen for AMPKα2 substrates uncovers a network of proteins involved in mitosis. Molecular Cell. 44: 878-92. PMID 22137581 DOI: 10.1016/J.Molcel.2011.11.005  0.795
2011 Greer EL, Maures TJ, Ucar D, Hauswirth AG, Mancini E, Lim JP, Benayoun BA, Shi Y, Brunet A. Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans. Nature. 479: 365-71. PMID 22012258 DOI: 10.1038/Nature10572  0.78
2011 Maures TJ, Greer EL, Hauswirth AG, Brunet A. The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner. Aging Cell. 10: 980-90. PMID 21834846 DOI: 10.1111/J.1474-9726.2011.00738.X  0.807
2011 Arnold CP, Tan R, Zhou B, Yue SB, Schaffert S, Biggs JR, Doyonnas R, Lo MC, Perry JM, Renault VM, Sacco A, Somervaille T, Viatour P, Brunet A, Cleary ML, et al. MicroRNA programs in normal and aberrant stem and progenitor cells. Genome Research. 21: 798-810. PMID 21451113 DOI: 10.1101/Gr.111385.110  0.324
2011 Pollina EA, Brunet A. Epigenetic regulation of aging stem cells. Oncogene. 30: 3105-26. PMID 21441951 DOI: 10.1038/Onc.2011.45  0.801
2011 Renault VM, Thekkat PU, Hoang KL, White JL, Brady CA, Kenzelmann Broz D, Venturelli OS, Johnson TM, Oskoui PR, Xuan Z, Santo EE, Zhang MQ, Vogel H, Attardi LD, Brunet A. The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor. Oncogene. 30: 3207-21. PMID 21423206 DOI: 10.1038/Onc.2011.35  0.323
2011 Brett JO, Renault VM, Rafalski VA, Webb AE, Brunet A. The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation. Aging. 3: 108-24. PMID 21386132  0.78
2011 Rafalski VA, Brunet A. Energy metabolism in adult neural stem cell fate. Progress in Neurobiology. 93: 182-203. PMID 21056618 DOI: 10.1016/J.Pneurobio.2010.10.007  0.78
2011 Greer E, Brunet A. The genetic network of life-span extension by dietary restriction Handbook of the Biology of Aging. 3-23. DOI: 10.1016/B978-0-12-378638-8.00001-4  0.613
2010 Greer EL, Maures TJ, Hauswirth AG, Green EM, Leeman DS, Maro GS, Han S, Banko MR, Gozani O, Brunet A. Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Nature. 466: 383-7. PMID 20555324 DOI: 10.1038/Nature09195  0.798
2010 de la Torre-Ubieta L, Gaudillière B, Yang Y, Ikeuchi Y, Yamada T, DiBacco S, Stegmüller J, Schüller U, Salih DA, Rowitch D, Brunet A, Bonni A. A FOXO-Pak1 transcriptional pathway controls neuronal polarity. Genes & Development. 24: 799-813. PMID 20395366 DOI: 10.1101/Gad.1880510  0.784
2010 Brunet A, Tran H, Greenberg ME. FOXO transcription factors. key targets of the pi3k-akt pathway that regulate cell proliferation, survival, and organismal aging Handbook of Cell Signaling, 2/E. 3: 2049-2057. DOI: 10.1016/B978-0-12-374145-5.00250-3  0.513
2009 Renault VM, Rafalski VA, Morgan AA, Salih DA, Brett JO, Webb AE, Villeda SA, Thekkat PU, Guillerey C, Denko NC, Palmer TD, Butte AJ, Brunet A. FoxO3 regulates neural stem cell homeostasis. Cell Stem Cell. 5: 527-39. PMID 19896443 DOI: 10.1016/J.Stem.2009.09.014  0.814
2009 Valenzano DR, Kirschner J, Kamber RA, Zhang E, Weber D, Cellerino A, Englert C, Platzer M, Reichwald K, Brunet A. Mapping loci associated with tail color and sex determination in the short-lived fish Nothobranchius furzeri. Genetics. 183: 1385-95. PMID 19786620 DOI: 10.1534/Genetics.109.108670  0.667
2009 Greer EL, Banko MR, Brunet A. AMP-activated protein kinase and FoxO transcription factors in dietary restriction-induced longevity. Annals of the New York Academy of Sciences. 1170: 688-92. PMID 19686213 DOI: 10.1111/J.1749-6632.2009.04019.X  0.815
2009 Greer EL, Brunet A. Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans. Aging Cell. 8: 113-27. PMID 19239417 DOI: 10.1111/J.1474-9726.2009.00459.X  0.678
2008 Salih DA, Brunet A. FoxO transcription factors in the maintenance of cellular homeostasis during aging. Current Opinion in Cell Biology. 20: 126-36. PMID 18394876 DOI: 10.1016/J.Ceb.2008.02.005  0.771
2008 Calnan DR, Brunet A. The FoxO code Oncogene. 27: 2276-2288. PMID 18391970 DOI: 10.1038/Onc.2008.21  0.411
2008 Greer EL, Brunet A. Signaling networks in aging. Journal of Cell Science. 121: 407-12. PMID 18256383 DOI: 10.1242/Jcs.021519  0.694
2008 Greer EL, Brunet A. FOXO transcription factors in ageing and cancer. Acta Physiologica (Oxford, England). 192: 19-28. PMID 18171426 DOI: 10.1111/J.1748-1716.2007.01780.X  0.716
2007 Brunet A. Aging and cancer: killing two birds with one worm. Nature Genetics. 39: 1306-7. PMID 17968345 DOI: 10.1038/Ng1107-1306  0.312
2007 Greer EL, Dowlatshahi D, Banko MR, Villen J, Hoang K, Blanchard D, Gygi SP, Brunet A. An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. Current Biology : Cb. 17: 1646-56. PMID 17900900 DOI: 10.1016/J.Cub.2007.08.047  0.807
2007 Brunet A, Rando TA. Ageing: from stem to stern. Nature. 449: 288-91. PMID 17882206 DOI: 10.1038/449288A  0.368
2007 Greer EL, Oskoui PR, Banko MR, Maniar JM, Gygi MP, Gygi SP, Brunet A. The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. The Journal of Biological Chemistry. 282: 30107-19. PMID 17711846 DOI: 10.1074/Jbc.M705325200  0.806
2007 Carter ME, Brunet A. FOXO transcription factors. Current Biology : Cb. 17: R113-4. PMID 17307039 DOI: 10.1016/J.Cub.2007.01.008  0.42
2005 Greer EL, Brunet A. FOXO transcription factors at the interface between longevity and tumor suppression. Oncogene. 24: 7410-25. PMID 16288288 DOI: 10.1038/Sj.Onc.1209086  0.706
2004 Brunet A. [The multiple roles of FOXO transcription factors]. MéDecine Sciences : M/S. 20: 856-9. PMID 15461960 DOI: 10.1051/Medsci/20042010856  0.315
2004 Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, Tran H, Ross SE, Mostoslavsky R, Cohen HY, Hu LS, Cheng HL, Jedrychowski MP, Gygi SP, Sinclair DA, et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science (New York, N.Y.). 303: 2011-5. PMID 14976264 DOI: 10.1126/Science.1094637  0.798
2003 Chou FL, Hill JM, Hsieh JC, Pouyssegur J, Brunet A, Glading A, Uberall F, Ramos JW, Werner MH, Ginsberg MH. PEA-15 binding to ERK1/2 MAPKs is required for its modulation of integrin activation. The Journal of Biological Chemistry. 278: 52587-97. PMID 14506247 DOI: 10.1074/Jbc.M309322200  0.52
2003 Tran H, Brunet A, Griffith EC, Greenberg ME. The many forks in FOXO's road. Science's Stke : Signal Transduction Knowledge Environment. 2003: RE5. PMID 12621150 DOI: 10.1126/Stke.2003.172.Re5  0.736
2002 Tran H, Brunet A, Grenier JM, Datta SR, Fornace AJ, DiStefano PS, Chiang LW, Greenberg ME. DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science (New York, N.Y.). 296: 530-4. PMID 11964479 DOI: 10.1126/Science.1068712  0.779
2002 Brunet A, Kanai F, Stehn J, Xu J, Sarbassova D, Frangioni JV, Dalal SN, DeCaprio JA, Greenberg ME, Yaffe MB. 14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport. The Journal of Cell Biology. 156: 817-28. PMID 11864996 DOI: 10.1083/Jcb.200112059  0.48
2002 Brunet A, Kanai F, Stehn J, Greenberg ME, Yaffe MB. Multiple roles for 14-3-3 proteins in nucleo-cytoplasmic transport Biochemical Society Transactions. 30: A64-A64. DOI: 10.1042/Bst030A064A  0.433
2001 Brunet A, Datta SR, Greenberg ME. Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway. Current Opinion in Neurobiology. 11: 297-305. PMID 11399427 DOI: 10.1016/S0959-4388(00)00211-7  0.693
2001 Brunet A, Park J, Tran H, Hu LS, Hemmings BA, Greenberg ME. Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Molecular and Cellular Biology. 21: 952-65. PMID 11154281 DOI: 10.1128/Mcb.21.3.952-965.2001  0.718
1999 Datta SR, Brunet A, Greenberg ME. Cellular survival: a play in three Akts. Genes & Development. 13: 2905-27. PMID 10579998 DOI: 10.1101/Gad.13.22.2905  0.695
1999 Bonni A, Brunet A, West AE, Datta SR, Takasu MA, Greenberg ME. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. Science (New York, N.Y.). 286: 1358-62. PMID 10558990 DOI: 10.1126/Science.286.5443.1358  0.794
1999 Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME. Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor. Cell. 96: 857-68. PMID 10102273 DOI: 10.1016/S0092-8674(00)80595-4  0.747
1999 Brunet A, Roux D, Lenormand P, Dowd S, Keyse S, Pouysségur J. Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry Embo Journal. 18: 664-674. PMID 9927426 DOI: 10.1093/Emboj/18.3.664  0.358
1998 Lenormand P, Brondello JM, Brunet A, Pouysségur J. Growth factor-induced p42/p44 MAPK nuclear translocation and retention requires both MAPK activation and neosynthesis of nuclear anchoring proteins. The Journal of Cell Biology. 142: 625-33. PMID 9700154 DOI: 10.1083/Jcb.142.3.625  0.494
1998 Englaro W, Bertolotto C, Buscà R, Brunet A, Pagès G, Ortonne JP, Ballotti R. Inhibition of the mitogen-activated protein kinase pathway triggers B16 melanoma cell differentiation Journal of Biological Chemistry. 273: 9966-9970. PMID 9545341 DOI: 10.1074/Jbc.273.16.9966  0.312
1997 Brondello JM, Brunet A, Pouysségur J, McKenzie FR. The dual specificity mitogen-activated protein kinase phosphatase-1 and -2 are induced by the p42/p44MAPK cascade. The Journal of Biological Chemistry. 272: 1368-76. PMID 8995446 DOI: 10.1074/Jbc.272.2.1368  0.306
1997 Brunet A, Lenormand P, Brondello J, McKenzie F, Pouysségur J. Growth factor activated MAP kinases: Mechanism of nuclear translocation and role in growth control European Journal of Cancer. 33: S223. DOI: 10.1016/S0959-8049(97)85779-6  0.503
1996 Lavoie JN, L'Allemain G, Brunet A, Müller R, Pouysségur J. Cyclin D1 Expression Is Regulated Positively by the p42/p44MAPK and Negatively by the p38/HOGMAPK Pathway Journal of Biological Chemistry. 271: 20608-20616. PMID 8702807 DOI: 10.1074/Jbc.271.34.20608  0.31
1996 Brunet A, Pouysségur J. Identification of MAP kinase domains by redirecting stress signals into growth factor responses Science. 272: 1652-1655. PMID 8658140 DOI: 10.1126/Science.272.5268.1652  0.519
1995 Pagès G, Stanley ER, Gall ML, Brunet A, Pouysségur J. The Mouse p44 Mitogen-activated Protein Kinase (Extracellular Signal-regulated Kinase 1) Gene GENOMIC ORGANIZATION AND STRUCTURE OF THE 5′-FLANKING REGULATORY REGION Journal of Biological Chemistry. 270: 26986-26992. PMID 7592946 DOI: 10.1074/Jbc.270.45.26986  0.549
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