Stefan Clemens, PhD, HdR - Publications

Affiliations: 
Physiology East Carolina University, Greenville, NC, United States 
Area:
spinal cord, neuromodulation, dopamine
Website:
http://www.clemenslab.org

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Silvani A, Ghorayeb I, Manconi M, Li Y, Clemens S. Putative Animal Models of Restless Legs Syndrome: A Systematic Review and Evaluation of Their Face and Construct Validity. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 36536233 DOI: 10.1007/s13311-022-01334-4  0.495
2022 Salminen AV, Clemens S, García-Borreguero D, Ghorayeb I, Li Y, Manconi M, Ondo W, Rye D, Siegel JM, Silvani A, Winkelman JW, Allen RP, Ferré S. Consensus guidelines on the construct validity of rodent models of restless legs syndrome. Disease Models & Mechanisms. 15. PMID 35946581 DOI: 10.1242/dmm.049615  0.416
2022 Clemens S. D3 Receptors and Restless Legs Syndrome. Current Topics in Behavioral Neurosciences. PMID 35435646 DOI: 10.1007/7854_2022_351  0.361
2021 Rodgers HM, Patton R, Yow J, Zeczycki TN, Kew K, Clemens S, Brewer KL. Morphine Resistance in Spinal Cord Injury-Related Neuropathic Pain in Rats is Associated With Alterations in Dopamine and Dopamine-Related Metabolomics. The Journal of Pain. PMID 34856409 DOI: 10.1016/j.jpain.2021.11.009  0.633
2020 Salminen AV, Silvani A, Allen RP, Clemens S, Garcia-Borreguero D, Ghorayeb I, Ferré S, Li Y, Ondo W, Picchietti DL, Rye D, Siegel JM, Winkelman JW, Manconi M. Consensus Guidelines on Rodent Models of Restless Legs Syndrome. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 33382140 DOI: 10.1002/mds.28401  0.416
2020 Johnson TL, Clemens S. Differential dopamine modulation of spinal reflex amplitudes is associated with the presence or absence of the autonomic nervous system. Neuroscience Letters. 135514. PMID 33227368 DOI: 10.1016/j.neulet.2020.135514  0.555
2020 Gaweda G, Iyer RP, Shaver PR, Grilo GA, Dinkins ML, Stoffel HJ, Clemens S, de Castro Brás LE. Dopamine receptor D3 agonist (Pramipexole) reduces morphine-induced cardiac fibrosis. Biochemical and Biophysical Research Communications. 529: 1080-1085. PMID 32819568 DOI: 10.1016/J.Bbrc.2020.06.137  0.327
2020 Lyu S, Doroodchi A, Xing H, Sheng Y, DeAndrade MP, Yang Y, Johnson TL, Clemens S, Yokoi F, Miller MA, Xiao R, Li Y. BTBD9 and dopaminergic dysfunction in the pathogenesis of restless legs syndrome. Brain Structure & Function. PMID 32468214 DOI: 10.1007/S00429-020-02090-X  0.618
2020 Rodgers HM, Lim SA, Yow J, Dinkins ML, Patton R, Clemens S, Brewer KL. Dopamine D or D receptor modulators prevent morphine tolerance and reduce opioid withdrawal symptoms. Pharmacology, Biochemistry, and Behavior. 172935. PMID 32335101 DOI: 10.1016/J.Pbb.2020.172935  0.635
2019 Clemens S, Ghorayeb I. D3 and D1 receptors: The Yin and Yang in the treatment of restless legs syndrome with dopaminergics. Advances in Pharmacology (San Diego, Calif.). 84: 79-100. PMID 31229178 DOI: 10.1016/Bs.Apha.2019.01.002  0.469
2019 Rodgers HM, Yow J, Evans E, Clemens S, Brewer KL. Dopamine D1 and D3 receptor modulators restore morphine analgesia and prevent opioid preference in a model of neuropathic pain. Neuroscience. PMID 30910641 DOI: 10.1016/J.Neuroscience.2019.03.034  0.641
2019 Lim S, Rodgers H, Jacob Y, Patton R, Clemens S, Brewer K. (283) Adjuvant Treatment with Dopamine Receptor Modulators Prevents the Development of Morphine Tolerance in a Rodent Model The Journal of Pain. 20: S45. DOI: 10.1016/J.Jpain.2019.01.205  0.612
2018 Meneely S, Dinkins ML, Kassai M, Lyu S, Liu Y, Lin CT, Brewer K, Li Y, Clemens S. Differential Dopamine D1 and D3 Receptor Modulation and Expression in the Spinal Cord of Two Mouse Models of Restless Legs Syndrome. Frontiers in Behavioral Neuroscience. 12: 199. PMID 30233336 DOI: 10.3389/Fnbeh.2018.00199  0.705
2018 Rivera-Oliver M, Moreno E, Álvarez-Bagnarol Y, Ayala-Santiago C, Cruz-Reyes N, Molina-Castro GC, Clemens S, Canela EI, Ferré S, Casadó V, Díaz-Ríos M. Adenosine A-Dopamine D Receptor Heteromers Control the Excitability of the Spinal Motoneuron. Molecular Neurobiology. PMID 29797183 DOI: 10.1007/S12035-018-1120-Y  0.474
2017 Ferré S, Quiroz C, Guitart X, Rea W, Seyedian A, Moreno E, Casadó-Anguera V, Díaz-Ríos M, Casadó V, Clemens S, Allen RP, Earley CJ, García-Borreguero D. Pivotal Role of Adenosine Neurotransmission in Restless Legs Syndrome. Frontiers in Neuroscience. 11: 722. PMID 29358902 DOI: 10.3389/Fnins.2017.00722  0.388
2017 Dinkins ML, Lallemand P, Clemens S. Long-term treatment with dopamine D3 receptor agonists induces a behavioral switch that can be rescued by blocking the dopamine D1 receptor. Sleep Medicine. 40: 47-52. PMID 29221778 DOI: 10.1016/J.Sleep.2017.10.001  0.408
2017 Samir S, Yllanes AP, Lallemand P, Brewer KL, Clemens S. Morphine responsiveness to thermal pain stimuli is aging-associated and mediated by dopamine D1 and D3 receptor interactions. Neuroscience. PMID 28257894 DOI: 10.1016/J.Neuroscience.2017.02.042  0.637
2017 Grilo G, Shaver P, Clemens S, Brás LdC. 044The Roles of Dopamine Receptor 3 in Age- and Sex-dependent Left Ventricular Remodeling Journal of Molecular and Cellular Cardiology. 112: 148-149. DOI: 10.1016/J.Yjmcc.2017.07.056  0.358
2016 Earley CJ, Uhl GR, Clemens S, Ferré S. Connectome and molecular pharmacological differences in the dopaminergic system in restless legs syndrome (RLS): plastic changes and neuroadaptations that may contribute to augmentation. Sleep Medicine. PMID 27539027 DOI: 10.1016/J.Sleep.2016.06.003  0.452
2015 Keeler BE, Lallemand P, Patel MM, de Castro Brás LE, Clemens S. Opposing aging-related shift of excitatory dopamine D1 and inhibitory D3 receptor protein expression in striatum and spinal cord. Journal of Neurophysiology. jn.00390.2015. PMID 26561599 DOI: 10.1152/Jn.00390.2015  0.799
2015 Sharples SA, Humphreys JM, Jensen AM, Dhoopar S, Delaloye N, Clemens S, Whelan PJ. Dopaminergic modulation of locomotor network activity in the neonatal mouse spinal cord. Journal of Neurophysiology. 113: 2500-10. PMID 25652925 DOI: 10.1152/Jn.00849.2014  0.488
2014 Brewer KL, Baran CA, Whitfield BR, Jensen AM, Clemens S. Dopamine D3 receptor dysfunction prevents anti-nociceptive effects of morphine in the spinal cord. Frontiers in Neural Circuits. 8: 62. PMID 24966815 DOI: 10.3389/Fncir.2014.00062  0.687
2013 Johnson TL, Tulis DA, Keeler BE, Virag JA, Lust RM, Clemens S. The dopamine D3 receptor knockout mouse mimics aging-related changes in autonomic function and cardiac fibrosis. Plos One. 8: e74116. PMID 24023697 DOI: 10.1371/Journal.Pone.0074116  0.734
2012 Keeler BE, Baran CA, Brewer KL, Clemens S. Increased excitability of spinal pain reflexes and altered frequency-dependent modulation in the dopamine D3-receptor knockout mouse. Experimental Neurology. 238: 273-83. PMID 22995602 DOI: 10.1016/J.Expneurol.2012.09.002  0.783
2012 Clemens S, Belin-Rauscent A, Simmers J, Combes D. Opposing modulatory effects of D1- and D2-like receptor activation on a spinal central pattern generator. Journal of Neurophysiology. 107: 2250-9. PMID 22262823 DOI: 10.1152/Jn.00366.2011  0.785
2011 Manconi M, Ferri R, Zucconi M, Clemens S, Giarolli L, Bottasini V, Ferini-Strambi L. Preferential D2 or preferential D3 dopamine agonists in restless legs syndrome. Neurology. 77: 110-7. PMID 21715702 DOI: 10.1212/Wnl.0B013E3182242D91  0.572
2011 Thorpe AJ, Clair A, Hochman S, Clemens S. Possible sites of therapeutic action in restless legs syndrome: focus on dopamine and α2δ ligands. European Neurology. 66: 18-29. PMID 21709418 DOI: 10.1159/000328431  0.653
2011 Manconi M, Ferri R, Zucconi M, Clemens S, Rundo F, Oldani A, Ferini-Strambi L. Effects of acute dopamine-agonist treatment in restless legs syndrome on heart rate variability during sleep. Sleep Medicine. 12: 47-55. PMID 20851046 DOI: 10.1016/J.Sleep.2010.03.019  0.532
2008 Zhu H, Clemens S, Sawchuk M, Hochman S. Unaltered D1, D2, D4, and D5 dopamine receptor mRNA expression and distribution in the spinal cord of the D3 receptor knockout mouse. Journal of Comparative Physiology. a, Neuroethology, Sensory, Neural, and Behavioral Physiology. 194: 957-62. PMID 18797877 DOI: 10.1007/S00359-008-0368-5  0.69
2007 Clemens S, Calin-Jageman R, Sakurai A, Katz PS. Altering cAMP levels within a central pattern generator modifies or disrupts rhythmic motor output. Journal of Comparative Physiology. a, Neuroethology, Sensory, Neural, and Behavioral Physiology. 193: 1265-71. PMID 17972082 DOI: 10.1007/S00359-007-0280-4  0.763
2007 Zhu H, Clemens S, Sawchuk M, Hochman S. Expression and distribution of all dopamine receptor subtypes (D(1)-D(5)) in the mouse lumbar spinal cord: a real-time polymerase chain reaction and non-autoradiographic in situ hybridization study. Neuroscience. 149: 885-97. PMID 17936519 DOI: 10.1016/J.Neuroscience.2007.07.052  0.698
2006 Clemens S, Rye D, Hochman S. Restless legs syndrome: revisiting the dopamine hypothesis from the spinal cord perspective. Neurology. 67: 125-30. PMID 16832090 DOI: 10.1212/01.Wnl.0000223316.53428.C9  0.714
2005 Clemens S, Sawchuk MA, Hochman S. Reversal of the circadian expression of tyrosine-hydroxylase but not nitric oxide synthase levels in the spinal cord of dopamine D3 receptor knockout mice. Neuroscience. 133: 353-7. PMID 15878801 DOI: 10.1016/J.Neuroscience.2005.03.002  0.696
2004 Clemens S, Hochman S. Conversion of the modulatory actions of dopamine on spinal reflexes from depression to facilitation in D3 receptor knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 11337-45. PMID 15601940 DOI: 10.1523/Jneurosci.3698-04.2004  0.7
2004 Katz PS, Sakurai A, Clemens S, Davis D. Cycle period of a network oscillator is independent of membrane potential and spiking activity in individual central pattern generator neurons. Journal of Neurophysiology. 92: 1904-17. PMID 15115787 DOI: 10.1152/Jn.00864.2003  0.711
2003 Clemens S, Katz PS. G protein signaling in a neuronal network is necessary for rhythmic motor pattern production. Journal of Neurophysiology. 89: 762-72. PMID 12574454 DOI: 10.1152/Jn.00765.2002  0.614
2001 Clemens S, Massabuau JC, Meyrand P, Simmers J. A modulatory role for oxygen in shaping rhythmic motor output patterns of neuronal networks. Respiration Physiology. 128: 299-315. PMID 11718760 DOI: 10.1016/S0034-5687(01)00308-5  0.774
2001 Katz PS, Clemens S. Biochemical networks in nervous systems: expanding neuronal information capacity beyond voltage signals. Trends in Neurosciences. 24: 18-25. PMID 11163883 DOI: 10.1016/S0166-2236(00)01686-6  0.574
2001 Clemens S, Katz PS. Identified serotonergic neurons in the Tritonia swim CPG activate both ionotropic and metabotropic receptors. Journal of Neurophysiology. 85: 476-9. PMID 11152750 DOI: 10.1152/Jn.2001.85.1.476  0.628
1999 Clemens S, Massabuau JC, Meyrand P, Simmers J. Changes in motor network expression related to moulting behaviour in lobster: role of moult-induced deep hypoxia The Journal of Experimental Biology. 202: 817-27. PMID 10069971  0.767
1998 Clemens S, Meyrand P, Simmers J. Feeding-induced changes in temporal patterning of muscle activity in the lobster stomatogastric system. Neuroscience Letters. 254: 65-8. PMID 9779921 DOI: 10.1016/S0304-3940(98)00511-4  0.762
1998 Clemens S, Massabuau JC, Legeay A, Meyrand P, Simmers J. In vivo modulation of interacting central pattern generators in lobster stomatogastric ganglion: influence of feeding and partial pressure of oxygen. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2788-99. PMID 9502835 DOI: 10.1523/Jneurosci.18-07-02788.1998  0.772
1998 Clemens S, Combes D, Meyrand P, Simmers J. Long-term expression of two interacting motor pattern-generating networks in the stomatogastric system of freely behaving lobster. Journal of Neurophysiology. 79: 1396-408. PMID 9497420 DOI: 10.1152/Jn.1998.79.3.1396  0.741
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