Francisco Silveira Guimaraes - Publications

Affiliations: 
Scholl of Medicine of Ribeirao Preto 
Area:
cannabinoids, nitric oxide, anxiety, depression, stress, glutamate

320 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Pedrazzi JFC, Silva-Amaral D, Issy AC, Gomes FV, Crippa JA, Guimarães FS, Del Bel E. Cannabidiol attenuates prepulse inhibition disruption by facilitating TRPV1 and 5-HT1A receptor-mediated neurotransmission. Pharmacology, Biochemistry, and Behavior. 245: 173879. PMID 39305939 DOI: 10.1016/j.pbb.2024.173879  0.729
2024 Souza AJ, Freitas ÍS, Sharmin D, Cook JM, Guimarães FS, Gomes FV. An alpha 5-GABA receptor positive allosteric modulator attenuates social and cognitive deficits without changing dopamine system hyperactivity in rats exposed to valproic acid in utero. Autism Research : Official Journal of the International Society For Autism Research. 17: 1534-1544. PMID 39169698 DOI: 10.1002/aur.3178  0.779
2024 Colodete DAE, Grace AA, Guimarães FS, Gomes FV. Degradation of Perineuronal Nets in the Ventral Hippocampus of Adult Rats Recreates an Adolescent-Like Phenotype of Stress Susceptibility. Biological Psychiatry Global Open Science. 4: 100338. PMID 39099729 DOI: 10.1016/j.bpsgos.2024.100338  0.744
2024 Fabris D, Lisboa JR, Guimarães FS, Gomes FV. Cannabidiol as an antipsychotic drug. International Review of Neurobiology. 177: 295-317. PMID 39029989 DOI: 10.1016/bs.irn.2024.04.013  0.713
2024 Dos Santos RG, da Silva Dias IC, Zuardi AW, Queiroz RHC, Guimarães FS, Hallak JEC, Crippa JAS. Lack of Acute Agomelatine Effect in a Model of Social Anxiety in Healthy Volunteers: A Double-Blind, Placebo-Controlled Trial. Journal of Clinical Psychopharmacology. PMID 39008875 DOI: 10.1097/JCP.0000000000001888  0.537
2024 Pagliusi M, Amorim-Marques AP, Lobo MK, Guimarães FS, Lisboa SF, Gomes FV. The rostral ventromedial medulla modulates pain and depression-related behaviors caused by social stress. Pain. PMID 38661577 DOI: 10.1097/j.pain.0000000000003257  0.79
2024 Santos-Silva T, Lopes CFB, Hazar Ülgen D, Guimarães DA, Guimarães FS, Alberici LC, Sandi C, Gomes FV. Adolescent Stress-Induced Ventral Hippocampus Redox Dysregulation Underlies Behavioral Deficits and Excitatory/Inhibitory Imbalance Related to Schizophrenia. Schizophrenia Bulletin. PMID 38525594 DOI: 10.1093/schbul/sbae033  0.712
2024 Silva NR, Gomes FIF, Lopes AHP, Cortez IL, Dos Santos JC, Silva CEA, Mechoulam R, Gomes FV, Cunha TM, Guimarães FS. The Cannabidiol Analog PECS-101 Prevents Chemotherapy-Induced Neuropathic Pain via PPARγ Receptors. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 19: 434-449. PMID 38176808 DOI: 10.1007/s13311-021-01164-w  0.725
2023 Fronza MG, Ferreira BF, Pavan-Silva I, Guimarães FS, Lisboa SF. "NO" Time in Fear Response: Possible Implication of Nitric-Oxide-Related Mechanisms in PTSD. Molecules (Basel, Switzerland). 29. PMID 38202672 DOI: 10.3390/molecules29010089  0.8
2023 Santos-Silva T, Hazar Ülgen D, Lopes CFB, Guimarães FS, Alberici LC, Sandi C, Gomes FV. Transcriptomic analysis reveals mitochondrial pathways associated with distinct adolescent behavioral phenotypes and stress response. Translational Psychiatry. 13: 351. PMID 37978166 DOI: 10.1038/s41398-023-02648-3  0.708
2023 Sales AJ, Joca SRL, Del Bel E, Guimarães FS. The antidepressant-like effect of doxycycline is associated with decreased nitric oxide metabolite levels in the prefrontal cortex. Behavioural Brain Research. 458: 114764. PMID 37972712 DOI: 10.1016/j.bbr.2023.114764  0.31
2023 Pinto JV, Crippa JAS, Ceresér KM, Vianna-Sulzbach MF, Silveira Júnior ÉM, Santana da Rosa G, Testa da Silva MG, Hizo GH, Simão Medeiros L, Santana de Oliveira CE, Bristot G, Campos AC, Guimarães FS, Hallak JEC, Zuardi AW, et al. Cannabidiol as an Adjunctive Treatment for Acute Bipolar Depression: A Pilot Study. Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie. 7067437231209650. PMID 37920963 DOI: 10.1177/07067437231209650  0.442
2023 Sales AJ, Gobira PH, Pedrazzi JFC, Silveira JR, Del Bel E, Gomes FV, Guimarães FS. Doxycycline diminishes the rewarding and psychomotor effects induced by morphine and cocaine. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 128: 110870. PMID 37793480 DOI: 10.1016/j.pnpbp.2023.110870  0.703
2023 Souza AJ, Sharmin D, Cook JM, Guimarães FS, Gomes FV. An alpha 5-GABAa receptor positive allosteric modulator attenuates social and cognitive deficits without changing dopamine system hyperactivity in an animal model for autism. Biorxiv : the Preprint Server For Biology. PMID 37662217 DOI: 10.1101/2023.08.24.554679  0.806
2023 Santos-Silva T, Dos Santos Fabris D, de Oliveira CL, Guimarães FS, Gomes FV. Prefrontal and Hippocampal Parvalbumin Interneurons in Animal Models for Schizophrenia: A Systematic Review and Meta-analysis. Schizophrenia Bulletin. PMID 37584417 DOI: 10.1093/schbul/sbad123  0.699
2023 Simei JLQ, Souza JDR, Lisboa JR, Campos AC, Guimarães FS, Zuardi A, Crippa JAS. Does the "Entourage Effect" in Cannabinoids Exist? A Narrative Scoping Review. Cannabis and Cannabinoid Research. PMID 37535820 DOI: 10.1089/can.2023.0052  0.448
2023 Crippa JAS, Guimarães FS, Zuardi AW, Hallak JEC. Prof. Dr Raphael Mechoulam, Cannabis and Cannabinoids Research Pioneer (November 05, 1930 - March 09, 2023) and his legacy for the Brazilian Pharmacology. Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999). PMID 37243978 DOI: 10.47626/1516-4446-2023-0047  0.415
2023 Ribeiro MA, Aguiar RP, Scarante FF, Fusse EJ, de Oliveira RMW, Guimarães FS, Campos AC. The chronic pharmacological antagonism of the CB receptor is not involved in the behavioral effects of antidepressants administered in mice submitted to chronic unpredictable stress. Behavioural Brain Research. 450: 114502. PMID 37211222 DOI: 10.1016/j.bbr.2023.114502  0.326
2023 Souza AJ, Guimarães FS, Gomes FV. Cannabidiol attenuates the expression of conditioned place aversion induced by naloxone-precipitated morphine withdrawal through the activation of 5-HT1A receptors. Behavioural Brain Research. 114504. PMID 37209879 DOI: 10.1016/j.bbr.2023.114504  0.814
2023 Colodete DAE, Silva NR, Pedrazzi JFC, Fogaça MV, Cortez I, Del-Bel EA, Breuer A, Mechoulam R, Gomes FV, Guimarães FS. Behavioral effects induced by the cannabidiol analogs HU-502 and HU-556. Behavioural Pharmacology. 34: 213-224. PMID 37171460 DOI: 10.1097/FBP.0000000000000727  0.724
2023 Borges-Assis AB, Uliana DL, Hott SC, Guimarães FS, Lisboa SF, Resstel LBM. Bed nucleus of the stria terminalis CB1 receptors and the FAAH enzyme modulate anxiety behavior depending on previous stress exposure. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 125: 110739. PMID 36870468 DOI: 10.1016/j.pnpbp.2023.110739  0.84
2022 Corsi-Zuelli F, Schneider AH, Santos-Silva T, Loureiro CM, Shuhama R, Menezes PR, Guimarães FS, Gomes FV, Cunha FQ, Louzada-Junior P, Del-Ben CM. Increased blood neutrophil extracellular traps (NETs) associated with early life stress: translational findings in recent-onset schizophrenia and rodent model. Translational Psychiatry. 12: 526. PMID 36572669 DOI: 10.1038/s41398-022-02291-4  0.689
2022 Souza JDR, Pacheco JC, Rossi GN, de-Paulo BO, Zuardi AW, Guimarães FS, Hallak JEC, Crippa JA, Dos Santos RG. Adverse Effects of Oral Cannabidiol: An Updated Systematic Review of Randomized Controlled Trials (2020-2022). Pharmaceutics. 14. PMID 36559092 DOI: 10.3390/pharmaceutics14122598  0.453
2022 Franzen JM, Werle I, Vanz F, de Oliveira BB, Martins Nascimento LM, Guimarães FS, Bertoglio LJ. Cannabidiol attenuates fear memory expression in female rats via hippocampal 5-HT but not CB1 or CB2 receptors. Neuropharmacology. 109316. PMID 36334768 DOI: 10.1016/j.neuropharm.2022.109316  0.34
2022 Souza JDS, Zuardi AW, Guimarães FS, Osório FL, Loureiro SR, Campos AC, Hallak JEC, Dos Santos RG, Machado Silveira IL, Pereira-Lima K, Pacheco JC, Ushirohira JM, Ferreira RR, Costa KCM, Scomparin DS, et al. Maintained anxiolytic effects of cannabidiol after treatment discontinuation in healthcare workers during the COVID-19 pandemic. Frontiers in Pharmacology. 13: 856846. PMID 36263136 DOI: 10.3389/fphar.2022.856846  0.466
2022 Cavichioli AM, Santos-Silva T, Grace AA, Guimarães FS, Gomes FV. Levetiracetam Attenuates Adolescent Stress-induced Behavioral and Electrophysiological Changes Associated With Schizophrenia in Adult Rats. Schizophrenia Bulletin. PMID 35988039 DOI: 10.1093/schbul/sbac106  0.761
2022 Coelho AA, Vila-Verde C, Sartim AG, Uliana DL, Braga LA, Guimarães FS, Lisboa SF. Inducible Nitric Oxide Synthase Inhibition in the Medial Prefrontal Cortex Attenuates the Anxiogenic-Like Effect of Acute Restraint Stress CB Receptors. Frontiers in Psychiatry. 13: 923177. PMID 35911236 DOI: 10.3389/fpsyt.2022.923177  0.824
2022 Pedrazzi JFC, Ferreira FR, Silva-Amaral D, Lima DA, Hallak JEC, Zuardi AW, Del-Bel EA, Guimarães FS, Costa KCM, Campos AC, Crippa ACS, Crippa JAS. Cannabidiol for the treatment of autism spectrum disorder: hope or hype? Psychopharmacology. 239: 2713-2734. PMID 35904579 DOI: 10.1007/s00213-022-06196-4  0.494
2022 Souza JDS, Fassoni-Ribeiro M, Batista RM, Ushirohira JM, Zuardi AW, Guimarães FS, Campos AC, Osório FL, Elias D, Souza CS, Fassoni AA, Hallak JEC, Crippa JAS. Case Report: Cannabidiol-Induced Skin Rash: A Case Series and Key Recommendations. Frontiers in Pharmacology. 13: 881617. PMID 35662726 DOI: 10.3389/fphar.2022.881617  0.422
2022 Hartmann A, Vila-Verde C, Guimarães FS, Joca SR, Lisboa SF. The NLRP3 inflammasome in stress response: another target for the promiscuous cannabidiol? Current Neuropharmacology. PMID 35410608 DOI: 10.2174/1570159X20666220411101217  0.709
2022 Cortez IL, Silva NR, Rodrigues NS, Pedrazzi JFC, Del Bel EA, Mechoulam R, Gomes FV, Guimarães FS. HU-910, a CB2 receptor agonist, reverses behavioral changes in pharmacological rodent models for schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 117: 110553. PMID 35341823 DOI: 10.1016/j.pnpbp.2022.110553  0.738
2022 Bolsoni LM, Crippa JAS, Hallak JEC, Guimarães FS, Zuardi AW. The anxiolytic effect of cannabidiol depends on the nature of the trauma when patients with post-traumatic stress disorder recall their trigger event. Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999). PMID 35293520 DOI: 10.1590/1516-4446-2021-2317  0.474
2022 Souza AJ, Cortez IL, Silva NR, Pedrazzi JFC, Domingos LB, Braga MS, Santos-Silva T, Del-Bel EA, Resstel LBM, Li G, Mian MY, Sharmin D, Guimarães FS, Cook JM, Gomes FV. Distinct sex-dependent behavioral responses induced by two positive allosteric modulators of alpha 5 subunit-containing GABA receptors. Behavioural Brain Research. 113832. PMID 35259414 DOI: 10.1016/j.bbr.2022.113832  0.804
2022 Ribeiro MA, Aguiar RP, Scarante FF, Fusse EJ, de Oliveira RMW, Guimaraes FS, Campos AC. Spontaneous Activity of CB Receptors Attenuates Stress-Induced Behavioral and Neuroplastic Deficits in Male Mice. Frontiers in Pharmacology. 12: 805758. PMID 35126139 DOI: 10.3389/fphar.2021.805758  0.33
2022 Bolsoni LM, Crippa JAS, Hallak JEC, Guimarães FS, Zuardi AW. Effects of cannabidiol on symptoms induced by the recall of traumatic events in patients with posttraumatic stress disorder. Psychopharmacology. PMID 35029706 DOI: 10.1007/s00213-021-06043-y  0.518
2021 Silva NR, Gomes FIF, Lopes AHP, Cortez IL, Dos Santos JC, Silva CEA, Mechoulam R, Gomes FV, Cunha TM, Guimarães FS. The Cannabidiol Analog PECS-101 Prevents Chemotherapy-Induced Neuropathic Pain via PPARγ Receptors. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 19: 434-449. PMID 34904193 DOI: 10.1007/s13311-021-01164-w  0.725
2021 Silva NR, Gomes FIF, Lopes AHP, Cortez IL, Dos Santos JC, Silva CEA, Mechoulam R, Gomes FV, Cunha TM, Guimarães FS. The Cannabidiol Analog PECS-101 Prevents Chemotherapy-Induced Neuropathic Pain via PPARγ Receptors. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 19: 434-449. PMID 34904193 DOI: 10.1007/s13311-021-01164-w  0.725
2021 Crippa JAS, Pacheco JC, Zuardi AW, Guimarães FS, Campos AC, Osório FL, Loureiro SR, Dos Santos RG, Souza JDS, Ushirohira JM, Ferreira RR, Mancini Costa KC, Scomparin DS, Scarante FF, Pires-Dos-Santos I, et al. Cannabidiol for COVID-19 Patients with Mild to Moderate Symptoms (CANDIDATE Study): A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Cannabis and Cannabinoid Research. PMID 34619044 DOI: 10.1089/can.2021.0093  0.439
2021 Crippa JAS, Zuardi AW, Guimarães FS, Campos AC, de Lima Osório F, Loureiro SR, Dos Santos RG, Souza JDS, Ushirohira JM, Pacheco JC, Ferreira RR, Mancini Costa KC, Scomparin DS, Scarante FF, Pires-Dos-Santos I, et al. Efficacy and Safety of Cannabidiol Plus Standard Care vs Standard Care Alone for the Treatment of Emotional Exhaustion and Burnout Among Frontline Health Care Workers During the COVID-19 Pandemic: A Randomized Clinical Trial. Jama Network Open. 4: e2120603. PMID 34387679 DOI: 10.1001/jamanetworkopen.2021.20603  0.408
2021 Crippa JA, Pereira Junior LC, Pereira LC, Zimmermann PM, Brum Junior L, Rechia LM, Dias I, Hallak JE, Campos AC, Guimarães FS, Queiroz RH, Zuardi AW. Effect of two oral formulations of cannabidiol on responses to emotional stimuli in healthy human volunteers: pharmaceutical vehicle matters. Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999). PMID 34076067 DOI: 10.1590/1516-4446-2020-1684  0.45
2021 Sonego AB, da Silva Prado D, Guimarães FS. PPARγ receptors are involved in the effects of cannabidiol on orofacial dyskinesia and cognitive dysfunction induced by typical antipsychotic in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110367. PMID 34048863 DOI: 10.1016/j.pnpbp.2021.110367  0.314
2021 Pacheco JC, Souza JDS, Hallak JEC, Osório FL, Campos AC, Guimarães FS, Zuardi AW, Crippa JAS. Cannabidiol as a Treatment for Mental Health Outcomes Among Health Care Workers During the Coronavirus Disease Pandemic. Journal of Clinical Psychopharmacology. 41: 327-329. PMID 33843818 DOI: 10.1097/JCP.0000000000001405  0.382
2021 Mori MA, Meyer E, da Silva FF, Milani H, Guimarães FS, Weffort de Oliveira RM. Differential contribution of CB1, CB2, 5-HT1A, and PPAR-γ receptors to cannabidiol effects on ischemia-induced emotional and cognitive impairments. The European Journal of Neuroscience. PMID 33522084 DOI: 10.1111/ejn.15134  0.307
2020 Linares IMP, Nardi AE, Guimarães FS, Arrais KC, Chagas MH, Osório FL, Hallak JE, Zuardi AW, Coimbra NC, Crippa JA. Increased body sway in phobic patients exposed to images of spiders. Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999). PMID 33331404 DOI: 10.1590/1516-4446-2020-1466  0.417
2020 Cortez IL, Rodrigues da Silva N, Guimarães FS, Gomes FV. Are CB2 Receptors a New Target for Schizophrenia Treatment? Frontiers in Psychiatry. 11: 587154. PMID 33329132 DOI: 10.3389/fpsyt.2020.587154  0.726
2020 Cuba LF, Salum FG, Guimarães FS, Cherubini K, Borghetti RL, de Figueiredo MAZ. Cannabidiol on 5-FU-induced oral mucositis in mice. Oral Diseases. PMID 32400905 DOI: 10.1111/Odi.13413  0.304
2020 Sales AJ, Guimarães FS, Joca SRL. CBD modulates DNA methylation in mice prefrontal cortex and hippocampus of mice exposed to forced swim. Behavioural Brain Research. 112627. PMID 32348868 DOI: 10.1016/J.Bbr.2020.112627  0.349
2020 Crippa JAS, Zuardi AW, Hallak JEC, Miyazawa B, Bernardo SA, Donaduzzi CM, Guzzi S, Favreto WAJ, Campos A, Queiroz MEC, Guimarães FS, da Rosa Zimmermann PM, Rechia LM, Jose Tondo Filho V, Brum Junior L. Oral Cannabidiol Does Not Convert to Δ-THC or Δ-THC in Humans: A Pharmacokinetic Study in Healthy Subjects. Cannabis and Cannabinoid Research. 5: 89-98. PMID 32322680 DOI: 10.1089/can.2019.0024  0.45
2020 Dos Santos RG, Guimarães FS, Crippa JAS, Hallak JEC, Rossi GN, Rocha JM, Zuardi AW. Serious adverse effects of cannabidiol (CBD): a review of randomized controlled trials. Expert Opinion On Drug Metabolism & Toxicology. PMID 32271618 DOI: 10.1080/17425255.2020.1754793  0.445
2020 da Silva NR, Gomes FV, Sonego AB, da Silva NR, Guimarães FS. Cannabidiol attenuates behavioral changes in a rodent model of schizophrenia through 5-HT1A, but not CB1 and CB2 receptors. Pharmacological Research. 104749. PMID 32151683 DOI: 10.1016/J.Phrs.2020.104749  0.762
2020 Crippa JA, de Lima Osório F, Hallak J, Guimarães FS, Zuardi AW. Cannabinoids for the treatment of mental disorders. The Lancet. Psychiatry. 7: 125-126. PMID 31981533 DOI: 10.1016/s2215-0366(19)30516-4  0.431
2019 Crivelaro do Nascimento G, Ferrari DP, Guimaraes FS, Del Bel EA, Bortolanza M, Ferreira-Junior NC. Cannabidiol increases the nociceptive threshold in a preclinical model of Parkinson's disease. Neuropharmacology. 163: 107808. PMID 31706993 DOI: 10.1016/J.Neuropharm.2019.107808  0.355
2019 Ferreira-Junior NC, Campos AC, Guimarães FS, Del-Bel E, Zimmermann PMDR, Brum Junior L, Hallak JE, Crippa JA, Zuardi AW. Biological bases for a possible effect of cannabidiol in Parkinson's disease. Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999). PMID 31314869 DOI: 10.1590/1516-4446-2019-0460  0.489
2019 Locachevic GA, Prado MKB, Zoccal KF, Pereira PAT, Sorgi CA, Bortolanza M, Peti APF, Fogaça MV, Guimarães FS, Del Bel E, Faccioli LH. Paradoxical Effect of LTB on the Regulation of Stress-Induced Corticosterone Production. Frontiers in Behavioral Neuroscience. 13: 73. PMID 31057373 DOI: 10.3389/Fnbeh.2019.00073  0.326
2019 Hartmann A, Lisboa SF, Sonego AB, Coutinho D, Gomes FV, Guimarães FS. Cannabidiol attenuates aggressive behavior induced by social isolation in mice: Involvement of 5-HT1A and CB1 receptors. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 94: 109637. PMID 31054943 DOI: 10.1016/J.Pnpbp.2019.109637  0.822
2019 Silote GP, Sartim A, Sales A, Eskelund A, Guimarães FS, Wegener G, Joca S. Emerging evidence for the antidepressant effect of cannabidiol and the underlying molecular mechanisms. Journal of Chemical Neuroanatomy. PMID 31039391 DOI: 10.1016/J.Jchemneu.2019.04.006  0.346
2019 Ribeiro DE, Casarotto PC, Júnior AS, Fernandes GG, Pinheiro LC, Dos Santos JET, Júnior HZ, Guimarães FS, Joca SRL, Biojone C. Activation of the TRKB receptor mediates the panicolytic-like effect of the NOS inhibitor aminoguanidine. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 30991078 DOI: 10.1016/J.Pnpbp.2019.04.007  0.403
2019 Diniz CRAF, Biojone C, Joca SRL, Rantamäki T, Castrén E, Guimarães FS, Casarotto PC. Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors. Peerj. 7: e6493. PMID 30809460 DOI: 10.7717/Peerj.6493  0.4
2019 Hartmann A, Fassini A, Scopinho A, Correa FM, Guimarães FS, Lisboa SF, Resstel LB. Role of the endocannabinoid system in the dorsal hippocampus in the cardiovascular changes and delayed anxiety-like effect induced by acute restraint stress in rats. Journal of Psychopharmacology (Oxford, England). 269881119827799. PMID 30789299 DOI: 10.1177/0269881119827799  0.82
2019 Crippa JAS, Hallak JEC, Zuardi AW, Guimarães FS, Tumas V, Dos Santos RG. Is cannabidiol the ideal drug to treat non-motor Parkinson's disease symptoms? European Archives of Psychiatry and Clinical Neuroscience. PMID 30706171 DOI: 10.1007/s00406-019-00982-6  0.464
2019 Lisboa SF, Vila-Verde C, Rosa J, Uliana DL, Stern CAJ, Bertoglio LJ, Resstel LB, Guimaraes FS. Tempering aversive/traumatic memories with cannabinoids: a review of evidence from animal and human studies. Psychopharmacology. PMID 30604182 DOI: 10.1007/s00213-018-5127-x  0.661
2018 Linares IM, Zuardi AW, Pereira LC, Queiroz RH, Mechoulam R, Guimarães FS, Crippa JA. Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test. Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999). PMID 30328956 DOI: 10.1590/1516-4446-2017-0015  0.492
2018 Crippa JA, Guimarães FS, Campos AC, Zuardi AW. Translational Investigation of the Therapeutic Potential of Cannabidiol (CBD): Toward a New Age. Frontiers in Immunology. 9: 2009. PMID 30298064 DOI: 10.3389/fimmu.2018.02009  0.483
2018 Sonego AB, Prado DS, Vale GT, Sepulveda-Diaz JE, Cunha TM, Tirapelli CR, Del Bel EA, Raisman-Vozari R, Guimarães FS. Cannabidiol prevents haloperidol-induced vacuos chewing movements and inflammatory changes in mice via PPARγ receptors. Brain, Behavior, and Immunity. PMID 30217539 DOI: 10.1016/J.Bbi.2018.09.014  0.438
2018 Perez M, Cartarozzi LP, Chiarotto GB, Oliveira SA, Guimarães FS, Oliveira ALR. Neuronal preservation and reactive gliosis attenuation following neonatal sciatic nerve axotomy by a fluorinated cannabidiol derivative. Neuropharmacology. 140: 201-208. PMID 30096328 DOI: 10.1016/J.Neuropharm.2018.08.009  0.313
2018 Sartim AG, Sales AJ, Guimarães FS, Joca SRL. Hippocampal mammalian target of rapamycin is implicated in stress-coping behavior induced by cannabidiol in the forced swim test. Journal of Psychopharmacology (Oxford, England). 269881118784877. PMID 29968502 DOI: 10.1177/0269881118784877  0.375
2018 Carvalho RK, Souza MR, Santos ML, Guimarães FS, Pobbe RLH, Andersen ML, Mazaro-Costa R. Chronic cannabidiol exposure promotes functional impairment in sexual behavior and fertility of male mice. Reproductive Toxicology (Elmsford, N.Y.). PMID 29936126 DOI: 10.1016/J.Reprotox.2018.06.013  0.312
2018 Sales AJ, Crestani CC, Guimarães FS, Joca SRL. Antidepressant-like effect induced by Cannabidiol is dependent on brain serotonin levels. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 29885468 DOI: 10.1016/J.Pnpbp.2018.06.002  0.396
2018 Sales AJ, Fogaça MV, Sartim AG, Pereira VS, Wegener G, Guimarães FS, Joca SRL. Cannabidiol Induces Rapid and Sustained Antidepressant-Like Effects Through Increased BDNF Signaling and Synaptogenesis in the Prefrontal Cortex. Molecular Neurobiology. PMID 29869197 DOI: 10.1007/S12035-018-1143-4  0.446
2018 Lisboa SF, Niraula A, Resstel LB, Guimaraes FS, Godbout JP, Sheridan JF. Repeated social defeat-induced neuroinflammation, anxiety-like behavior and resistance to fear extinction were attenuated by the cannabinoid receptor agonist WIN55,212-2. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29786066 DOI: 10.1038/S41386-018-0064-2  0.828
2018 Carvalho RK, Santos ML, Souza MR, Rocha TL, Guimarães FS, Anselmo-Franci JA, Mazaro-Costa R. Chronic exposure to cannabidiol induces reproductive toxicity in male Swiss mice. Journal of Applied Toxicology : Jat. PMID 29766538 DOI: 10.1002/Jat.3631  0.305
2018 de Oliveira RW, Oliveira CL, Guimarães FS, Campos AC. Cannabinoid signalling in embryonic and adult neurogenesis: possible implications for psychiatric and neurological disorders. Acta Neuropsychiatrica. 1-16. PMID 29764526 DOI: 10.1017/Neu.2018.11  0.34
2018 Casarotto PC, Biojone C, Montezuma K, Cunha FQ, Joca SRL, Castren E, Guimaraes FS. Inducible nitric oxide synthase (NOS2) knockout mice as a model of trichotillomania. Peerj. 6: e4635. PMID 29682419 DOI: 10.7717/Peerj.4635  0.362
2018 Linares IMP, Guimaraes FS, Eckeli A, Crippa ACS, Zuardi AW, Souza JDS, Hallak JE, Crippa JAS. No Acute Effects of Cannabidiol on the Sleep-Wake Cycle of Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study. Frontiers in Pharmacology. 9: 315. PMID 29674967 DOI: 10.3389/Fphar.2018.00315  0.508
2018 Fogaça MV, de Campos AC, Coelho LD, Duman RS, Guimarães FS. The anxiolytic effects of cannabidiol in chronically stressed mice are mediated by the endocannabinoid system: Role of neurogenesis and dendritic remodeling. Neuropharmacology. PMID 29510186 DOI: 10.1016/J.Neuropharm.2018.03.001  0.42
2018 Diniz CRAF, Becari C, Lesnikova A, Biojone C, Salgado MCO, Salgado HC, Resstel LBM, Guimarães FS, Castrén E, Casarotto PC, Joca SRL. Elastase-2 Knockout Mice Display Anxiogenic- and Antidepressant-Like Phenotype: Putative Role for BDNF Metabolism in Prefrontal Cortex. Molecular Neurobiology. PMID 29383685 DOI: 10.1007/S12035-018-0902-6  0.373
2018 Lisboa SF, Issy AC, Biojone C, Montezuma K, Fattori V, Del-Bel EA, Guimarães FS, Cunha FQ, Verri WA, Joca SRL. Mice lacking interleukin-18 gene display behavioral changes in animal models of psychiatric disorders: Possible involvement of immunological mechanisms. Journal of Neuroimmunology. 314: 58-66. PMID 29195684 DOI: 10.1016/J.Jneuroim.2017.11.008  0.706
2018 Crippa JA, Zuardi AW, Guimaraes FS. 17.4 POSSIBLE MECHANISMS INVOLVED IN THE ANTIPSYCHOTIC EFFECTS OF CANNABIDIOL (CBD) Schizophrenia Bulletin. 44: S28-S28. DOI: 10.1093/Schbul/Sby014.068  0.632
2018 Guimaraes F, Rodrigues N, Silva N, Gomes F. 13.2 CANNABIDIOL AS AN ANTIPSYCHOTIC DRUG Schizophrenia Bulletin. 44: S21-S22. DOI: 10.1093/Schbul/Sby014.050  0.662
2017 Scarante FF, Vila-Verde C, Detoni VL, Ferreira-Junior NC, Guimarães FS, Campos AC. Cannabinoid Modulation of the Stressed Hippocampus. Frontiers in Molecular Neuroscience. 10: 411. PMID 29311804 DOI: 10.3389/Fnmol.2017.00411  0.41
2017 Stanquini LA, Biojone C, Guimarães FS, Joca SR. Repeated treatment with nitric oxide synthase inhibitor attenuates learned helplessness development in rats and increases hippocampal BDNF expression. Acta Neuropsychiatrica. 30: 127-136. PMID 29151391 DOI: 10.1017/Neu.2017.28  0.348
2017 Reckziegel P, Festuccia WT, Britto LRG, Jang KLL, Romão CM, Heimann JC, Fogaça MV, Rodrigues NS, Silva NR, Guimarães FS, Eichler RAS, Gupta A, Gomes I, Devi LA, Heimann AS, et al. A novel peptide that improves metabolic parameters without adverse central nervous system effects. Scientific Reports. 7: 14781. PMID 29093454 DOI: 10.1038/S41598-017-13690-9  0.362
2017 Gambeta E, Sestile CC, Fogaça MV, Guimarães FS, Audi EA, da Cunha JM, Zangrossi H, Shimene de Melo Yamashita P, Zanoveli JM. A serotonergic deficit in the dorsal periaqueductal gray matter may underpin enhanced panic-like behavior in diabetic rats. Behavioural Pharmacology. PMID 28799955 DOI: 10.1097/Fbp.0000000000000332  0.454
2017 Stern CAJ, da Silva TR, Raymundi AM, de Souza CP, Hiroaki-Sato VA, Kato L, Guimarães FS, Andreatini R, Takahashi RN, Bertoglio LJ. Cannabidiol disrupts the consolidation of specific and generalized fear memories via dorsal hippocampus CB1 and CB2 receptors. Neuropharmacology. 125: 220-230. PMID 28754373 DOI: 10.1016/J.Neuropharm.2017.07.024  0.402
2017 Silva NR, Gomes FV, Fonseca MD, Mechoulam R, Breuer A, Cunha TM, Guimarães FS. Antinociceptive effects of HUF-101, a fluorinated cannabidiol derivative. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 28720466 DOI: 10.1016/J.Pnpbp.2017.07.012  0.756
2017 Campos AC, Fogaça MV, Scarante FF, Joca SRL, Sales AJ, Gomes FV, Sonego AB, Rodrigues NS, Galve-Roperh I, Guimarães FS. Plastic and Neuroprotective Mechanisms Involved in the Therapeutic Effects of Cannabidiol in Psychiatric Disorders. Frontiers in Pharmacology. 8: 269. PMID 28588483 DOI: 10.3389/Fphar.2017.00269  0.752
2017 Zuardi AW, Rodrigues NP, Silva AL, Bernardo SA, Hallak JEC, Guimarães FS, Crippa JAS. Inverted U-Shaped Dose-Response Curve of the Anxiolytic Effect of Cannabidiol during Public Speaking in Real Life. Frontiers in Pharmacology. 8: 259. PMID 28553229 DOI: 10.3389/Fphar.2017.00259  0.533
2017 Almeida-Santos AF, Moreira FA, Guimaraes FS, Aguiar DC. 2-Arachidonoylglycerol endocannabinoid signaling coupled to metabotropic glutamate receptor type-5 modulates anxiety-like behavior in the rat ventromedial prefrontal cortex. Journal of Psychopharmacology (Oxford, England). 269881117704986. PMID 28440729 DOI: 10.1177/0269881117704986  0.462
2017 Lee JL, Bertoglio LJ, Guimarães FS, Stevenson CW. Cannabidiol regulation of emotion and emotional memory processing: relevance for treating anxiety-related and substance abuse disorders. British Journal of Pharmacology. PMID 28268256 DOI: 10.1111/Bph.13724  0.348
2017 Lisboa SF, Gomes FV, Terzian AL, Aguiar DC, Moreira FA, Resstel LB, Guimarães FS. The Endocannabinoid System and Anxiety. Vitamins and Hormones. 103: 193-279. PMID 28061971 DOI: 10.1016/Bs.Vh.2016.09.006  0.813
2016 Song C, Stevenson CW, Guimaraes FS, Lee JL. Bidirectional Effects of Cannabidiol on Contextual Fear Memory Extinction. Frontiers in Pharmacology. 7: 493. PMID 28018227 DOI: 10.3389/Fphar.2016.00493  0.349
2016 Jurkus R, Day HL, Guimarães FS, Lee JL, Bertoglio LJ, Stevenson CW. Cannabidiol Regulation of Learned Fear: Implications for Treating Anxiety-Related Disorders. Frontiers in Pharmacology. 7: 454. PMID 27932983 DOI: 10.3389/Fphar.2016.00454  0.346
2016 Mori MA, Meyer E, Soares LM, Milani H, Guimarães FS, de Oliveira RM. Cannabidiol reduces neuroinflammation and promotes neuroplasticity and functional recovery after brain ischemia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 27889412 DOI: 10.1016/J.Pnpbp.2016.11.005  0.345
2016 Breuer A, Haj CG, Fogaça MV, Gomes FV, Silva NR, Pedrazzi JF, Del Bel EA, Hallak JC, Crippa JA, Zuardi AW, Mechoulam R, Guimarães FS. Correction: Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects. Plos One. 11: e0162087. PMID 27560809 DOI: 10.1371/journal.pone.0162087  0.731
2016 Breuer A, Haj CG, Fogaça MV, Gomes FV, Silva NR, Pedrazzi JF, Del Bel EA, Hallak JC, Crippa JA, Zuardi AW, Mechoulam R, Guimarães FS. Fluorinated Cannabidiol Derivatives: Enhancement of Activity in Mice Models Predictive of Anxiolytic, Antidepressant and Antipsychotic Effects. Plos One. 11: e0158779. PMID 27416026 DOI: 10.1371/Journal.Pone.0158779  0.785
2016 Santos-Pereira MD, da-Silva CA, Guimarães FS, Del-Bel E. Co-administration of cannabidiol and capsazepine reduces L-DOPA-induced dyskinesia in mice: Possible mechanism of action. Neurobiology of Disease. PMID 27373843 DOI: 10.1016/J.Nbd.2016.06.013  0.397
2016 Sonego AB, Gomes FV, Del Bel EA, Guimaraes FS. Cannabidiol attenuates haloperidol-induced catalepsy and c-Fos protein expression in the dorsolateral striatum via 5-HT1A receptors in mice. Behavioural Brain Research. PMID 27131780 DOI: 10.1016/J.Bbr.2016.04.042  0.773
2016 Fogaça MV, Fedoce AG, Ferreira-Junior NC, Guimarães FS, Resstel LB. Involvement of M1 and CB₁ receptors in the anxiogenic-like effects induced by neostigmine injected into the rat prelimbic medial prefrontal cortex. Psychopharmacology. 233: 1377-85. PMID 26873081 DOI: 10.1007/S00213-016-4228-7  0.773
2016 Lisboa SF, Gomes FV, Guimaraes FS, Campos AC. Microglial Cells as a Link between Cannabinoids and the Immune Hypothesis of Psychiatric Disorders. Frontiers in Neurology. 7: 5. PMID 26858686 DOI: 10.3389/Fneur.2016.00005  0.791
2016 Campos AC, Fogaça MV, Sonego AB, Guimarães FS. Cannabidiol, neuroprotection and neuropsychiatric disorders. Pharmacological Research. PMID 26845349 DOI: 10.1016/J.Phrs.2016.01.033  0.359
2016 Vila-Verde C, Marinho ALZ, Lisboa SF, Guimarães FS. Nitric oxide in the prelimbic medial prefrontal cortex is involved in the anxiogenic-like effect induced by acute restraint stress in rats. Neuroscience. 320: 30-42. PMID 26812037 DOI: 10.1016/J.Neuroscience.2016.01.040  0.739
2016 Sartim AG, Guimarães FS, Joca SR. Antidepressant-like effect of cannabidiol injection into the ventral medial prefrontal cortex-Possible involvement of 5-HT1A and CB1 receptors. Behavioural Brain Research. 303: 218-27. PMID 26801828 DOI: 10.1016/J.Bbr.2016.01.033  0.453
2016 Schiavon AP, Bonato JM, Milani H, Guimarães FS, Weffort de Oliveira RM. Influence of single and repeated cannabidiol administration on emotional behavior and markers of cell proliferation and neurogenesis in non-stressed mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 64: 27-34. PMID 26187374 DOI: 10.1016/J.Pnpbp.2015.06.017  0.409
2016 Joca S, Sales AJ, Sartim AG, Pereira VS, Wegener G, Guimaraes FS. PS137. Evidence that Cannabidiol Induces Acute Antidepressant-Like Efects in Different Animal Models The International Journal of Neuropsychopharmacology. 19: 46-47. DOI: 10.1093/Ijnp/Pyw043.137  0.312
2016 Linares I, Zuardi AW, Pereira LCG, Queiroz RHC, Mechoulam R, Guimarães FS, Crippa JAS. Cannabidiol presents an inverted U-shaped dose-response curve in the simulated public speaking test European Neuropsychopharmacology. 26. DOI: 10.1016/S0924-977X(16)31702-3  0.502
2016 Linares I, Guimarães FS, Eckeli A, Zuardi AW, Souza JDS, Hallak JEC, Crippa JAS. Lack of cannabidiol effects on sleep-wake cycle in healthy patients European Neuropsychopharmacology. 26. DOI: 10.1016/S0924-977X(16)31310-4  0.458
2016 Lisboa S, Niraula A, Shea D, Resstel L, Guimaraes F, Godbout J, Sheridan J. Abstract # 1831 Repeated social defeat stress-induced neuroinflammation contributes to later fear sensitization and impaired extinction recall of fear conditioning in mice: Involvement of the endocannabinoid system Brain, Behavior, and Immunity. 57: e35. DOI: 10.1016/J.Bbi.2016.07.116  0.742
2015 Gobira PH, Almeida-Santos AF, Guimaraes FS, Moreira FA, Aguiar DC. Role of the endocannabinoid 2-arachidonoylglycerol in aversive responses mediated by the dorsolateral periaqueductal grey. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 26628106 DOI: 10.1016/J.Euroneuro.2015.11.014  0.411
2015 Batista PA, Fogaça MV, Guimarães FS. The endocannabinoid, endovanilloid and nitrergic systems could interact in the rat dorsolateral periaqueductal gray matter to control anxiety-like behaviors. Behavioural Brain Research. 293: 182-8. PMID 26187694 DOI: 10.1016/J.Bbr.2015.07.019  0.437
2015 Pedrazzi JF, Issy AC, Gomes FV, Guimarães FS, Del-Bel EA. Cannabidiol effects in the prepulse inhibition disruption induced by amphetamine. Psychopharmacology. 232: 3057-65. PMID 25943166 DOI: 10.1007/S00213-015-3945-7  0.713
2015 Kandratavicius L, Balista PA, Wolf DC, Abrao J, Evora PR, Rodrigues AJ, Chaves C, Maia-de-Oliveira JP, Leite JP, Dursun SM, Baker GB, Guimaraes FS, Hallak JE. Effects of nitric oxide-related compounds in the acute ketamine animal model of schizophrenia. Bmc Neuroscience. 16: 9. PMID 25887360 DOI: 10.1186/S12868-015-0149-3  0.325
2015 Casarotto PC, Santos PC, Lucas GA, Biojone C, Pobbe RL, Vilela-Costa HH, Joca SR, Guimarães FS, Zangrossi H. BDNF-TRKB signaling system of the dorsal periaqueductal gray matter is implicated in the panicolytic-like effect of antidepressant drugs. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 25: 913-22. PMID 25840741 DOI: 10.1016/J.Euroneuro.2015.03.004  0.348
2015 Stern CA, Gazarini L, Vanvossen AC, Zuardi AW, Galve-Roperh I, Guimaraes FS, Takahashi RN, Bertoglio LJ. Δ(9)-Tetrahydrocannabinol alone and combined with cannabidiol mitigate fear memory through reconsolidation disruption. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 25: 958-65. PMID 25799920 DOI: 10.1016/J.Euroneuro.2015.02.001  0.574
2015 Marinho AL, Vila-Verde C, Fogaça MV, Guimarães FS. Effects of intra-infralimbic prefrontal cortex injections of cannabidiol in the modulation of emotional behaviors in rats: contribution of 5HT₁A receptors and stressful experiences. Behavioural Brain Research. 286: 49-56. PMID 25701682 DOI: 10.1016/J.Bbr.2015.02.023  0.449
2015 Gomes FV, Llorente R, Del Bel EA, Viveros MP, López-Gallardo M, Guimarães FS. Decreased glial reactivity could be involved in the antipsychotic-like effect of cannabidiol. Schizophrenia Research. 164: 155-63. PMID 25680767 DOI: 10.1016/J.Schres.2015.01.015  0.753
2015 Lisboa SF, Gomes FV, Silva AL, Uliana DL, Camargo LH, Guimarães FS, Cunha FQ, Joca SR, Resstel LB. Increased Contextual Fear Conditioning in iNOS Knockout Mice: Additional Evidence for the Involvement of Nitric Oxide in Stress-Related Disorders and Contribution of the Endocannabinoid System. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25618404 DOI: 10.1093/Ijnp/Pyv005  0.801
2015 Gomes FV, Issy AC, Ferreira FR, Viveros MP, Del Bel EA, Guimarães FS. Cannabidiol attenuates sensorimotor gating disruption and molecular changes induced by chronic antagonism of NMDA receptors in mice. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25618402 DOI: 10.1093/Ijnp/Pyu041  0.76
2015 Lisboa SF, Borges AA, Nejo P, Fassini A, Guimarães FS, Resstel LB. Cannabinoid CB1 receptors in the dorsal hippocampus and prelimbic medial prefrontal cortex modulate anxiety-like behavior in rats: additional evidence. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 59: 76-83. PMID 25595265 DOI: 10.1016/J.Pnpbp.2015.01.005  0.84
2015 Aguiar DC, Almeida-Santos AF, Moreira FA, Guimarães FS. Involvement of TRPV1 channels in the periaqueductal grey on the modulation of innate fear responses. Acta Neuropsychiatrica. 27: 97-105. PMID 25529842 DOI: 10.1017/Neu.2014.40  0.427
2015 Gomes FV, Guimarães FS, Grace AA. Effects of pubertal cannabinoid administration on attentional set-shifting and dopaminergic hyper-responsivity in a developmental disruption model of schizophrenia. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18. PMID 25522381 DOI: 10.1093/Ijnp/Pyu018  0.773
2015 Chaves C, Marque CR, Maia-de-Oliveira JP, Wichert-Ana L, Ferrari TB, Santos AC, Araújo D, Machado-de-Sousa JP, Bressan RA, Elkis H, Crippa JA, Guimarães FS, Zuardi AW, Baker GB, Dursun SM, et al. Effects of minocycline add-on treatment on brain morphometry and cerebral perfusion in recent-onset schizophrenia. Schizophrenia Research. 161: 439-45. PMID 25497439 DOI: 10.1016/J.Schres.2014.11.031  0.527
2015 Fogaça MV, Sonego AB, Rioli V, Gozzo FC, Dale CS, Ferro ES, Guimarães FS. Anxiogenic-like effects induced by hemopressin in rats. Pharmacology, Biochemistry, and Behavior. 129: 7-13. PMID 25462856 DOI: 10.1016/J.Pbb.2014.11.013  0.413
2015 Casarotto PC, Gomes FV, Guimarães FS. Cannabinoids and obsessive-compulsive disorder Cannabinoids in Neurologic and Mental Disease. 365-387. DOI: 10.1016/B978-0-12-417041-4.00015-1  0.674
2014 Gomes FV, Kakihata AM, Semedo AC, Hott SC, Uliana DL, Guimarães FS, Resstel LB. D-cycloserine injected into the dorsolateral periaqueductal gray induces anxiolytic-like effects in rats. Behavioural Brain Research. 271: 374-9. PMID 24931794 DOI: 10.1016/J.Bbr.2014.06.009  0.812
2014 Aguiar DC, Moreira FA, Terzian AL, Fogaça MV, Lisboa SF, Wotjak CT, Guimaraes FS. Modulation of defensive behavior by Transient Receptor Potential Vanilloid Type-1 (TRPV1) channels. Neuroscience and Biobehavioral Reviews. 46: 418-28. PMID 24726577 DOI: 10.1016/J.Neubiorev.2014.03.026  0.815
2014 Schiavon AP, Soares LM, Bonato JM, Milani H, Guimarães FS, Weffort de Oliveira RM. Protective effects of cannabidiol against hippocampal cell death and cognitive impairment induced by bilateral common carotid artery occlusion in mice. Neurotoxicity Research. 26: 307-16. PMID 24532152 DOI: 10.1007/S12640-014-9457-0  0.351
2014 Lisboa SF, Camargo LH, Magesto AC, Resstel LB, Guimarães FS. Cannabinoid modulation of predator fear: involvement of the dorsolateral periaqueductal gray. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 17: 1193-206. PMID 24438603 DOI: 10.1017/S1461145713001788  0.758
2014 Fogaça MV, Reis FM, Campos AC, Guimarães FS. Effects of intra-prelimbic prefrontal cortex injection of cannabidiol on anxiety-like behavior: involvement of 5HT1A receptors and previous stressful experience. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 410-9. PMID 24321837 DOI: 10.1016/J.Euroneuro.2013.10.012  0.5
2014 Nardo M, Casarotto PC, Gomes FV, Guimarães FS. Cannabidiol reverses the mCPP-induced increase in marble-burying behavior. Fundamental & Clinical Pharmacology. 28: 544-50. PMID 24118015 DOI: 10.1111/Fcp.12051  0.758
2014 Aguiar DC, Hott SC, Deolindo MV, Guimarães FS, Resstel LB. The dorsolateral periaqueductal grey N-methyl-D-aspartate/nitric oxide/cyclic guanosine monophosphate pathway modulates the expression of contextual fear conditioning in rats. Journal of Psychopharmacology (Oxford, England). 28: 479-85. PMID 24008812 DOI: 10.1177/0269881113504012  0.755
2014 Terzian AL, dos Reis DG, Guimarães FS, Corrêa FM, Resstel LB. Medial prefrontal cortex Transient Receptor Potential Vanilloid Type 1 (TRPV1) in the expression of contextual fear conditioning in Wistar rats. Psychopharmacology. 231: 149-57. PMID 23922023 DOI: 10.1007/S00213-013-3211-9  0.827
2014 Batalla A, Crippa JA, Busatto GF, Guimaraes FS, Zuardi AW, Valverde O, Atakan Z, McGuire PK, Bhattacharyya S, Martín-Santos R. Neuroimaging studies of acute effects of THC and CBD in humans and animals: a systematic review. Current Pharmaceutical Design. 20: 2168-85. PMID 23829359 DOI: 10.2174/13816128113199990432  0.521
2014 Del-Bel E, Padovan-Neto FE, Szawka RE, da-Silva CA, Raisman-Vozari R, Anselmo-Franci J, Romano-Dutra AC, Guimaraes FS. Counteraction by nitric oxide synthase inhibitor of neurochemical alterations of dopaminergic system in 6-OHDA-lesioned rats under L-DOPA treatment. Neurotoxicity Research. 25: 33-44. PMID 23807548 DOI: 10.1007/S12640-013-9406-3  0.313
2014 Fogaça MV, Campos AC, Guimarães FS. P.4.c.002 Behavioural effects of cannabidiol in chronically stressed mice is mediated by neurogenesis and autophagy through CB1 receptor activation European Neuropsychopharmacology. 24. DOI: 10.1016/S0924-977X(14)70972-1  0.368
2014 Lisboa S, Camargo L, Da Silva A, Resstel L, Guimarães F. P.4.a.014 Repeated treatment with an anandamide metabolism inhibitor attenuates long-lasting consequences in a mouse model of post-traumatic stress disorder (PTSD) European Neuropsychopharmacology. 24: S584-S585. DOI: 10.1016/S0924-977X(14)70936-8  0.785
2014 Stern CA, Gazarmi L, Vanvossen AC, Zuardi AW, Guimarães FS, Takahashi RN, Bertoglio LJ. P.1.j.006 Involvement of the prelimbic cortex in the disruptive effect of cannabidiol on fear memory reconsolidation European Neuropsychopharmacology. 24. DOI: 10.1016/S0924-977X(14)70511-5  0.524
2013 Campos AC, Fogaça MV, Aguiar DC, Guimarães FS. Animal models of anxiety disorders and stress. Revista Brasileira De Psiquiatria (Sã£O Paulo, Brazil : 1999). 35: S101-11. PMID 24271222 DOI: 10.1590/1516-4446-2013-1139  0.39
2013 Fogaça MV, Galve-Roperh I, Guimarães FS, Campos AC. Cannabinoids, Neurogenesis and Antidepressant Drugs: Is there a Link? Current Neuropharmacology. 11: 263-75. PMID 24179463 DOI: 10.2174/1570159X11311030003  0.398
2013 Scopinho AA, Lisboa SF, Guimarães FS, Corrêa FM, Resstel LB, Joca SR. Dorsal and ventral hippocampus modulate autonomic responses but not behavioral consequences associated to acute restraint stress in rats. Plos One. 8: e77750. PMID 24147071 DOI: 10.1371/Journal.Pone.0077750  0.823
2013 Campos AC, Piorino EM, Ferreira FR, Guimarães FS. Increased nitric oxide-mediated neurotransmission in the medial prefrontal cortex is associated with the long lasting anxiogenic-like effect of predator exposure. Behavioural Brain Research. 256: 391-7. PMID 23948217 DOI: 10.1016/J.Bbr.2013.08.006  0.428
2013 Lisboa SF, Magesto AC, Aguiar JC, Resstel LB, Guimarães FS. Complex interaction between anandamide and the nitrergic system in the dorsolateral periaqueductal gray to modulate anxiety-like behavior in rats. Neuropharmacology. 75: 86-94. PMID 23899460 DOI: 10.1016/J.Neuropharm.2013.07.008  0.837
2013 Gomes FV, Del Bel EA, Guimarães FS. Cannabidiol attenuates catalepsy induced by distinct pharmacological mechanisms via 5-HT1A receptor activation in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 46: 43-7. PMID 23791616 DOI: 10.1016/J.Pnpbp.2013.06.005  0.767
2013 Almeida-Santos AF, Gobira PH, Rosa LC, Guimaraes FS, Moreira FA, Aguiar DC. Modulation of anxiety-like behavior by the endocannabinoid 2-arachidonoylglycerol (2-AG) in the dorsolateral periaqueductal gray. Behavioural Brain Research. 252: 10-7. PMID 23714073 DOI: 10.1016/J.Bbr.2013.05.027  0.384
2013 Alves FH, Gomes FV, Reis DG, Crestani CC, Corrêa FM, Guimarães FS, Resstel LB. Involvement of the insular cortex in the consolidation and expression of contextual fear conditioning. The European Journal of Neuroscience. 38: 2300-7. PMID 23574437 DOI: 10.1111/Ejn.12210  0.797
2013 Almeida-Santos AF, Moreira FA, Guimarães FS, Aguiar DC. Role of TRPV1 receptors on panic-like behaviors mediated by the dorsolateral periaqueductal gray in rats. Pharmacology, Biochemistry, and Behavior. 105: 166-72. PMID 23474373 DOI: 10.1016/J.Pbb.2013.02.012  0.504
2013 Tonelli DA, Pereira M, Siba IP, Martynhak BJ, Correia D, Casarotto PC, Biojone C, Guimarães FS, Joca SL, Andreatini R. The antimanic-like effect of phenytoin and carbamazepine on methylphenidate-induced hyperlocomotion: role of voltage-gated sodium channels. Fundamental & Clinical Pharmacology. 27: 650-5. PMID 23437921 DOI: 10.1111/Fcp.12022  0.303
2013 Pereira VS, Casarotto PC, Hiroaki-Sato VA, Sartim AG, Guimarães FS, Joca SR. Antidepressant- and anticompulsive-like effects of purinergic receptor blockade: involvement of nitric oxide. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 23: 1769-78. PMID 23434291 DOI: 10.1016/J.Euroneuro.2013.01.008  0.489
2013 Campos AC, Ortega Z, Palazuelos J, Fogaça MV, Aguiar DC, Díaz-Alonso J, Ortega-Gutiérrez S, Vázquez-Villa H, Moreira FA, Guzmán M, Galve-Roperh I, Guimarães FS. The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 1407-19. PMID 23298518 DOI: 10.1017/S1461145712001502  0.414
2013 Fogaça MV, Gomes FV, Moreira FA, Guimarães FS, Aguiar DC. Effects of glutamate NMDA and TRPV1 receptor antagonists on the biphasic responses to anandamide injected into the dorsolateral periaqueductal grey of Wistar rats. Psychopharmacology. 226: 579-87. PMID 23183551 DOI: 10.1007/S00213-012-2927-2  0.769
2013 Campos AC, Ferreira FR, da Silva WA, Guimarães FS. Predator threat stress promotes long lasting anxiety-like behaviors and modulates synaptophysin and CB1 receptors expression in brain areas associated with PTSD symptoms. Neuroscience Letters. 533: 34-8. PMID 23178193 DOI: 10.1016/J.Neulet.2012.11.016  0.424
2013 Gomes FV, Alves FH, Guimarães FS, Correa FM, Resstel LB, Crestani CC. Cannabidiol administration into the bed nucleus of the stria terminalis alters cardiovascular responses induced by acute restraint stress through 5-HT₁A receptor. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 23: 1096-104. PMID 23041353 DOI: 10.1016/J.Euroneuro.2012.09.007  0.823
2013 Campos AC, de Paula Soares V, Carvalho MC, Ferreira FR, Vicente MA, Brandão ML, Zuardi AW, Zangrossi H, Guimarães FS. Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats. Psychopharmacology. 226: 13-24. PMID 23007604 DOI: 10.1007/S00213-012-2878-7  0.616
2012 Campos AC, Moreira FA, Gomes FV, Del Bel EA, Guimarães FS. Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 367: 3364-78. PMID 23108553 DOI: 10.1098/Rstb.2011.0389  0.775
2012 Campos AC, Ferreira FR, Guimarães FS. Cannabidiol blocks long-lasting behavioral consequences of predator threat stress: possible involvement of 5HT1A receptors. Journal of Psychiatric Research. 46: 1501-10. PMID 22979992 DOI: 10.1016/J.Jpsychires.2012.08.012  0.472
2012 Zuardi AW, Crippa JA, Hallak JE, Bhattacharyya S, Atakan Z, Martin-Santos R, McGuire PK, Guimarães FS. A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation. Current Pharmaceutical Design. 18: 5131-40. PMID 22716160 DOI: 10.2174/138161212802884681  0.578
2012 Fogaça MV, Aguiar DC, Moreira FA, Guimarães FS. The endocannabinoid and endovanilloid systems interact in the rat prelimbic medial prefrontal cortex to control anxiety-like behavior. Neuropharmacology. 63: 202-10. PMID 22691536 DOI: 10.1016/J.Neuropharm.2012.03.007  0.477
2012 Stern CA, Gazarini L, Takahashi RN, Guimarães FS, Bertoglio LJ. On disruption of fear memory by reconsolidation blockade: evidence from cannabidiol treatment. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2132-42. PMID 22549120 DOI: 10.1038/Npp.2012.63  0.386
2012 Scopinho AA, Aguiar DC, Resstel LB, Guimarães FS, Corrêa FM. Brain pathways involved in the modulatory effects of noradrenaline in lateral septal area on cardiovascular responses. Cellular and Molecular Neurobiology. 32: 1147-57. PMID 22484835 DOI: 10.1007/S10571-012-9840-4  0.731
2012 Lisboa SF, Guimarães FS. Differential role of CB1 and TRPV1 receptors on anandamide modulation of defensive responses induced by nitric oxide in the dorsolateral periaqueductal gray. Neuropharmacology. 62: 2455-62. PMID 22394688 DOI: 10.1016/J.Neuropharm.2012.02.008  0.766
2012 Fogaça MV, Lisboa SF, Aguiar DC, Moreira FA, Gomes FV, Casarotto PC, Guimarães FS. Fine-tuning of defensive behaviors in the dorsal periaqueductal gray by atypical neurotransmitters. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 45: 357-65. PMID 22392189 DOI: 10.1590/S0100-879X2012007500029  0.826
2012 Ferreira FR, Oliveira AM, Dinarte AR, Pinheiro DG, Greene LJ, Silva WA, Joca SR, Guimarães FS. Changes in hippocampal gene expression by 7-nitroindazole in rats submitted to forced swimming stress. Genes, Brain, and Behavior. 11: 303-13. PMID 22142142 DOI: 10.1111/J.1601-183X.2011.00757.X  0.369
2012 Silva M, Aguiar DC, Diniz CR, Guimarães FS, Joca SR. Neuronal NOS inhibitor and conventional antidepressant drugs attenuate stress-induced fos expression in overlapping brain regions. Cellular and Molecular Neurobiology. 32: 443-53. PMID 22120186 DOI: 10.1007/S10571-011-9775-1  0.419
2012 Montezuma K, Biojone C, Lisboa SF, Cunha FQ, Guimarães FS, Joca SR. Inhibition of iNOS induces antidepressant-like effects in mice: pharmacological and genetic evidence. Neuropharmacology. 62: 485-91. PMID 21939674 DOI: 10.1016/J.Neuropharm.2011.09.004  0.739
2012 Casarotto PC, Terzian AL, Aguiar DC, Zangrossi H, Guimarães FS, Wotjak CT, Moreira FA. Opposing roles for cannabinoid receptor type-1 (CB₁) and transient receptor potential vanilloid type-1 channel (TRPV1) on the modulation of panic-like responses in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 478-86. PMID 21937980 DOI: 10.1038/Npp.2011.207  0.832
2012 Moreira FA, Aguiar DC, Terzian AL, Guimarães FS, Wotjak CT. Cannabinoid type 1 receptors and transient receptor potential vanilloid type 1 channels in fear and anxiety-two sides of one coin? Neuroscience. 204: 186-92. PMID 21906661 DOI: 10.1016/J.Neuroscience.2011.08.046  0.81
2012 Moreira FA, Aguiar DC, Resstel LB, Lisboa SF, Campos AC, Gomes FV, Guimarães FS. Neuroanatomical substrates involved in cannabinoid modulation of defensive responses. Journal of Psychopharmacology (Oxford, England). 26: 40-55. PMID 21616976 DOI: 10.1177/0269881111400651  0.813
2012 Gomes FV, Reis DG, Alves FH, Corrêa FM, Guimarães FS, Resstel LB. Cannabidiol injected into the bed nucleus of the stria terminalis reduces the expression of contextual fear conditioning via 5-HT1A receptors. Journal of Psychopharmacology (Oxford, England). 26: 104-13. PMID 21148020 DOI: 10.1177/0269881110389095  0.821
2012 Gomes FV, Issy AC, Del-Bel E, Guimaräes FS. Poster #222 CANNABIDIOL ATTENUATES THE IMPAIRMENTS IN PREPULSE INHIBITION INDUCED BY REPEATED TREATMENT WITH MK-801 IN MICE Schizophrenia Research. 136: S265-S266. DOI: 10.1016/S0920-9964(12)70793-4  0.709
2011 Crestani CC, Tavares RF, Guimarães FS, Correa FM, Joca SR, Resstel LB. Chronic fluoxetine treatment alters cardiovascular functions in unanesthetized rats. European Journal of Pharmacology. 670: 527-33. PMID 21963526 DOI: 10.1016/j.ejphar.2011.09.030  0.766
2011 de Paula Soares V, Vicente MA, Biojone C, Zangrossi H, Guimarães FS, Joca SR. Distinct behavioral consequences of stress models of depression in the elevated T-maze. Behavioural Brain Research. 225: 590-5. PMID 21896290 DOI: 10.1016/J.Bbr.2011.08.032  0.41
2011 Reis DG, Scopinho AA, Guimarães FS, Corrêa FM, Resstel LB. Behavioral and autonomic responses to acute restraint stress are segregated within the lateral septal area of rats. Plos One. 6: e23171. PMID 21858017 DOI: 10.1371/Journal.Pone.0023171  0.736
2011 Zuardi AW, Guimarães FS, Hallak JE, Crippa JA. Is the highest density of CB1 receptors in paranoid schizophrenia a correlate of endocannabinoid system functioning? Expert Review of Neurotherapeutics. 11: 1111-4. PMID 21797651 DOI: 10.1586/ern.11.89  0.497
2011 Granjeiro EM, Gomes FV, Guimarães FS, Corrêa FM, Resstel LB. Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress. Pharmacology, Biochemistry, and Behavior. 99: 743-8. PMID 21771609 DOI: 10.1016/J.Pbb.2011.06.027  0.811
2011 Sales AJ, Biojone C, Terceti MS, Guimarães FS, Gomes MV, Joca SR. Antidepressant-like effect induced by systemic and intra-hippocampal administration of DNA methylation inhibitors. British Journal of Pharmacology. 164: 1711-21. PMID 21585346 DOI: 10.1111/J.1476-5381.2011.01489.X  0.343
2011 Aguiar DC, Guimarães FS. Blockade of NMDA or NO in the dorsal premammillary nucleus attenuates defensive behaviors. Physiology & Behavior. 103: 279-83. PMID 21362437 DOI: 10.1016/J.Physbeh.2011.02.034  0.427
2011 Scopinho AA, Guimarães FS, Corrêa FM, Resstel LB. Cannabidiol inhibits the hyperphagia induced by cannabinoid-1 or serotonin-1A receptor agonists. Pharmacology, Biochemistry, and Behavior. 98: 268-72. PMID 21238476 DOI: 10.1016/J.Pbb.2011.01.007  0.732
2011 Gomes FV, Casarotto PC, Resstel LB, Guimarães FS. Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35: 434-8. PMID 21111767 DOI: 10.1016/J.Pnpbp.2010.11.027  0.827
2011 Gomes FV, Resstel LB, Guimarães FS. The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors. Psychopharmacology. 213: 465-73. PMID 20945065 DOI: 10.1007/S00213-010-2036-Z  0.839
2011 Salum C, Issy AC, Brandão ML, Guimarães FS, Bel EA. Nitric oxide modulates dopaminergic regulation of prepulse inhibition in the basolateral amygdala. Journal of Psychopharmacology (Oxford, England). 25: 1639-48. PMID 20837567 DOI: 10.1177/0269881110379282  0.379
2011 Biojone C, Casarotto PC, Resstel LB, Zangrossi H, Guimarães FS, Moreira FA. Anti-aversive effects of the atypical antipsychotic, aripiprazole, in animal models of anxiety. Journal of Psychopharmacology (Oxford, England). 25: 801-7. PMID 20699351 DOI: 10.1177/0269881110376690  0.766
2011 Lisboa SF, Guimarães FS, Resstel LB. Anxiety-Behavior Modulated by Ventral Medial Prefrontal Cortex of Rats Submitted to the Vogel Conflict Test Involves a Local NMDA Receptor and Nitric Oxide Journal of Behavioral and Brain Science. 1: 181-187. DOI: 10.4236/Jbbs.2011.13024  0.826
2011 Montezuma K, Biojone C, Lisboa S, Guimarães FS, Cunha TM, Cunha FQ, Joca SR. P.2.b.020 Antidepressant -like effect induced by pharmacological or genetic inhibition of inducible nitric oxide synthase in mice European Neuropsychopharmacology. 21. DOI: 10.1016/S0924-977X(11)70608-3  0.69
2011 Casarotto PC, Pereira VS, Sato VAH, Sartim AG, Guimaraes FS, Joca SRL. P.1.c.004 Purinergic receptor blockade induces antidepressant- and anticompulsive-like effects European Neuropsychopharmacology. 21. DOI: 10.1016/S0924-977X(11)70395-9  0.364
2011 Terzian A, Casarotto P, Aguiar D, Zangrossi H, Guimarães F, Wotjak C, Moreira F. P.2.003 CB1 and TRPV1 receptors located in periaqueductal gray matter mediate opposite effects in panic-like responses in rats European Neuropsychopharmacology. 21: S37. DOI: 10.1016/S0924-977X(11)70043-8  0.816
2010 Canteras NS, Resstel LB, Bertoglio LJ, Carobrez Ade P, Guimarães FS. Neuroanatomy of anxiety. Current Topics in Behavioral Neurosciences. 2: 77-96. PMID 21309107 DOI: 10.1007/7854_2009_7  0.73
2010 Lisboa SF, Stecchini MF, Corrêa FM, Guimarães FS, Resstel LB. Different role of the ventral medial prefrontal cortex on modulation of innate and associative learned fear. Neuroscience. 171: 760-8. PMID 20883749 DOI: 10.1016/J.Neuroscience.2010.09.048  0.82
2010 Casarotto PC, Gomes FV, Resstel LB, Guimarães FS. Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors. Behavioural Pharmacology. 21: 353-8. PMID 20695034 DOI: 10.1097/Fbp.0B013E32833B33C5  0.825
2010 Alves FH, Crestani CC, Gomes FV, Guimarães FS, Correa FM, Resstel LB. Cannabidiol injected into the bed nucleus of the stria terminalis modulates baroreflex activity through 5-HT1A receptors. Pharmacological Research. 62: 228-36. PMID 20621717 DOI: 10.1016/J.Phrs.2010.05.003  0.816
2010 Scopinho AA, Scopinho M, Lisboa SF, Correa FM, Guimarães FS, Joca SR. Acute reversible inactivation of the ventral medial prefrontal cortex induces antidepressant-like effects in rats. Behavioural Brain Research. 214: 437-42. PMID 20600346 DOI: 10.1016/J.Bbr.2010.06.018  0.779
2010 Lisboa SF, Reis DG, da Silva AL, Corrêa FM, Guimarães FS, Resstel LB. Cannabinoid CB1 receptors in the medial prefrontal cortex modulate the expression of contextual fear conditioning. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 13: 1163-73. PMID 20587131 DOI: 10.1017/S1461145710000684  0.825
2010 Crestani CC, Alves FH, Correa FM, Guimarães FS, Joca SR. Acute reversible inactivation of the bed nucleus of stria terminalis induces antidepressant-like effect in the rat forced swimming test. Behavioral and Brain Functions : Bbf. 6: 30. PMID 20515458 DOI: 10.1186/1744-9081-6-30  0.614
2010 Trzesniak C, Uchida RR, Araújo D, Guimarães FS, Freitas-Ferrari MC, Filho AS, Santos AC, Busatto GF, Zuardi AW, Del-Ben CM, Graeff FG, Crippa JA. (1)H magnetic resonance spectroscopy imaging of the hippocampus in patients with panic disorder. Psychiatry Research. 182: 261-5. PMID 20488674 DOI: 10.1016/J.Pscychresns.2010.03.008  0.534
2010 Soares Vde P, Campos AC, Bortoli VC, Zangrossi H, Guimarães FS, Zuardi AW. Intra-dorsal periaqueductal gray administration of cannabidiol blocks panic-like response by activating 5-HT1A receptors. Behavioural Brain Research. 213: 225-9. PMID 20457188 DOI: 10.1016/J.Bbr.2010.05.004  0.635
2010 Reis DG, Scopinho AA, Guimarães FS, Corrêa FM, Resstel LB. Involvement of the lateral septal area in the expression of fear conditioning to context. Learning & Memory (Cold Spring Harbor, N.Y.). 17: 134-8. PMID 20189957 DOI: 10.1101/Lm.1534710  0.782
2010 Campos AC, Ferreira FR, Guimarães FS, Lemos JI. Facilitation of endocannabinoid effects in the ventral hippocampus modulates anxiety-like behaviors depending on previous stress experience. Neuroscience. 167: 238-46. PMID 20167262 DOI: 10.1016/J.Neuroscience.2010.01.062  0.452
2010 Zanelati TV, Biojone C, Moreira FA, Guimarães FS, Joca SRL. Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors British Journal of Pharmacology. 159: 122-128. PMID 20002102 DOI: 10.1111/J.1476-5381.2009.00521.X  0.442
2010 Lemos JI, Resstel LB, Guimarães FS. Involvement of the prelimbic prefrontal cortex on cannabidiol-induced attenuation of contextual conditioned fear in rats. Behavioural Brain Research. 207: 105-11. PMID 19800921 DOI: 10.1016/J.Bbr.2009.09.045  0.742
2010 Garcia-Leal C, Del-Ben CM, Leal FM, Graeff FG, Guimarães FS. Escitalopram prolonged fear induced by simulated public speaking and released hypothalamic-pituitary-adrenal axis activation. Journal of Psychopharmacology (Oxford, England). 24: 683-94. PMID 19251828 DOI: 10.1177/0269881108101782  0.389
2010 Del-Bel EA, Guimarães FS, Joca SRL, Echeverry MB, Ferreira FR. Tolerance to the cataleptic effect that follows repeated nitric oxide synthase inhibition may be related to functional enzymatic recovery. Journal of Psychopharmacology. 24: 397-405. PMID 18838497 DOI: 10.1177/0269881108097717  0.379
2010 Guimarães FS, Zangrossi H, Ben CMD, Graeff FG. Serotonin in panic and anxiety disorders Handbook of Behavioral Neuroscience. 21: 667-685. DOI: 10.1016/S1569-7339(10)70105-3  0.328
2010 Marque C, Chaves C, Wichert-Ana L, Crippa JAS, Zuardi AW, Baker GB, Guimarães FS, Dursun SM, Hallak JEC. P.1.e.004 Effects of minocycline on regional cerebral blood flow in schizophrenia European Neuropsychopharmacology. 20. DOI: 10.1016/S0924-977X(10)70383-7  0.488
2010 Terzian A, Casarotto P, Aguiar DC, Zangrossi H, Guimaraes FS, Wotjak CT, Moreira FA. Opposing roles of CB1 and TRPV1 in panic-like responses mediated by dorsal periaqueductal gray European Neuropsychopharmacology. 20. DOI: 10.1016/S0924-977X(10)70303-5  0.802
2009 Tonetto LL, Terzian AL, Del Bel EA, Guimarães FS, Resstel LB. Inhibition of the NMDA receptor/Nitric Oxide pathway in the dorsolateral periaqueductal gray causes anxiolytic-like effects in rats submitted to the Vogel conflict test. Behavioral and Brain Functions : Bbf. 5: 40. PMID 19775445 DOI: 10.1186/1744-9081-5-40  0.81
2009 Campos AC, Guimarães FS. Evidence for a potential role for TRPV1 receptors in the dorsolateral periaqueductal gray in the attenuation of the anxiolytic effects of cannabinoids Progress in Neuro-Psychopharmacology and Biological Psychiatry. 33: 1517-1521. PMID 19735690 DOI: 10.1016/J.Pnpbp.2009.08.017  0.445
2009 Resstel LB, Moreira FA, Guimarães FS. Endocannabinoid system and fear conditioning. Vitamins and Hormones. 81: 421-40. PMID 19647121 DOI: 10.1016/S0083-6729(09)81016-9  0.713
2009 Braga AA, Aguiar DC, Guimarães FS. NOC-9, a selective nitric oxide donor, induces flight reactions in the dorsolateral periaqueductal gray of rats by activating soluble guanylate cyclase. Neuroscience Letters. 459: 79-83. PMID 19427360 DOI: 10.1016/J.Neulet.2009.05.009  0.388
2009 Pelosi GG, Resstel LL, Soares VP, Zangrossi H, Guimarães FS, Corrêa FM. Anxiolytic-like effect of noradrenaline microinjection into the dorsal periaqueductal gray of rats. Behavioural Pharmacology. 20: 252-9. PMID 19407657 DOI: 10.1097/Fbp.0B013E32832C7098  0.796
2009 Aguiar DC, Terzian AL, Guimarães FS, Moreira FA. Anxiolytic-like effects induced by blockade of transient receptor potential vanilloid type 1 (TRPV1) channels in the medial prefrontal cortex of rats. Psychopharmacology. 205: 217-25. PMID 19387617 DOI: 10.1007/S00213-009-1532-5  0.822
2009 Aguiar DC, Guimarães FS. Blockade of NMDA receptors and nitric oxide synthesis in the dorsolateral periaqueductal gray attenuates behavioral and cellular responses of rats exposed to a live predator. Journal of Neuroscience Research. 87: 2418-29. PMID 19360885 DOI: 10.1002/Jnr.22082  0.414
2009 Issy AC, da Silva CA, Guimarães FS, Del Bel EA. Different role of isoproterenol and NOS inhibitors on salivary ducts of rats. Micron (Oxford, England : 1993). 40: 343-9. PMID 19167231 DOI: 10.1016/J.Micron.2008.10.007  0.328
2009 Resstel LB, Tavares RF, Lisboa SF, Joca SR, Corrêa FM, Guimarães FS. 5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats. British Journal of Pharmacology. 156: 181-8. PMID 19133999 DOI: 10.1111/J.1476-5381.2008.00046.X  0.816
2009 Moreira FA, Aguiar DC, Campos AC, Lisboa SF, Terzian AL, Resstel LB, Guimarães FS. Antiaversive effects of cannabinoids: is the periaqueductal gray involved? Neural Plasticity. 2009: 625469. PMID 19096514 DOI: 10.1155/2009/625469  0.833
2009 Napimoga MH, Benatti BB, Lima FO, Alves PM, Campos AC, Pena-Dos-Santos DR, Severino FP, Cunha FQ, Guimarães FS. Cannabidiol decreases bone resorption by inhibiting RANK/RANKL expression and pro-inflammatory cytokines during experimental periodontitis in rats. International Immunopharmacology. 9: 216-22. PMID 19070683 DOI: 10.1016/J.Intimp.2008.11.010  0.323
2009 Terzian AL, Aguiar DC, Guimarães FS, Moreira FA. Modulation of anxiety-like behaviour by Transient Receptor Potential Vanilloid Type 1 (TRPV1) channels located in the dorsolateral periaqueductal gray. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 19: 188-95. PMID 19064314 DOI: 10.1016/J.Euroneuro.2008.11.004  0.818
2009 Aguiar D, Terzian A, Guimaraes F. P.4.b.003 Anxiolytic effects of 6-iodonordihydrocapsaicin, a TRPV1 antagonist, injected into the medial prefrontal cortex of rats European Neuropsychopharmacology. 19: S597-S598. DOI: 10.1016/S0924-977X(09)70958-7  0.791
2009 Lisboa S, Guimãraes F. P.4.b.00l Endocannabinoids modulate the flight responses induced by a nitric oxide donor in the dorsolateral periaqueductal gray European Neuropsychopharmacology. 19: S596-S597. DOI: 10.1016/S0924-977X(09)70956-3  0.652
2009 Guimaraes FS, Scopinho AA, Scopinho MA, Correa FMA, Joca SRL. P.2.d.007 Reversible inactivation of the medial prefrontal cortex induces antidepressant-like effects in rats European Neuropsychopharmacology. 19. DOI: 10.1016/S0924-977X(09)70673-X  0.345
2009 Ferreira F, Joca S, Pinheiro D, Santos A, Silva W, Catalan A, Greene L, Guimaraes F. P.2.d.005 Effects of chronic treatment with 7-nitroindazole on rat hippocampal gene and protein expression after swimming stress European Neuropsychopharmacology. 19. DOI: 10.1016/S0924-977X(09)70671-6  0.311
2009 Garcia-Leal C, Del-Ben C, Leal F, Graeff F, Guimarães F. P02-229 Escitalopram prolonged fear induced by simulated public speaking and released hypothalamic-pituitary-adrenal axis activation European Psychiatry. 24: S919. DOI: 10.1016/S0924-9338(09)71152-6  0.392
2008 Ferreira FR, Biojone C, Joca SR, Guimarães FS. Antidepressant-like effects of N-acetyl-L-cysteine in rats. Behavioural Pharmacology. 19: 747-50. PMID 18797252 DOI: 10.1097/Fbp.0B013E3283123C98  0.397
2008 Lisboa SF, Resstel LB, Aguiar DC, Guimarães FS. Activation of cannabinoid CB1 receptors in the dorsolateral periaqueductal gray induces anxiolytic effects in rats submitted to the Vogel conflict test. European Journal of Pharmacology. 593: 73-8. PMID 18691568 DOI: 10.1016/J.Ejphar.2008.07.032  0.842
2008 Resstel LB, Alves FH, Reis DG, Crestani CC, Corrêa FM, Guimarães FS. Anxiolytic-like effects induced by acute reversible inactivation of the bed nucleus of stria terminalis. Neuroscience. 154: 869-76. PMID 18479825 DOI: 10.1016/J.Neuroscience.2008.04.007  0.757
2008 Resstel LB, Lisboa SF, Aguiar DC, Corrêa FM, Guimarães FS. Activation of CB1 cannabinoid receptors in the dorsolateral periaqueductal gray reduces the expression of contextual fear conditioning in rats. Psychopharmacology. 198: 405-11. PMID 18446325 DOI: 10.1007/S00213-008-1156-1  0.82
2008 Campos AC, Guimarães FS. Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats Psychopharmacology. 199: 223-230. PMID 18446323 DOI: 10.1007/S00213-008-1168-X  0.467
2008 Oliveira RM, Guimarães FS, Deakin JF. Expression of neuronal nitric oxide synthase in the hippocampal formation in affective disorders. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 41: 333-41. PMID 18392456 DOI: 10.1590/S0100-879X2008000400012  0.621
2008 Resstel LB, Joca SR, Corrêa FM, Guimarães FS. Effects of reversible inactivation of the dorsal hippocampus on the behavioral and cardiovascular responses to an aversive conditioned context. Behavioural Pharmacology. 19: 137-44. PMID 18332678 DOI: 10.1097/Fbp.0B013E3282F62C9E  0.791
2008 Moreira FA, Guimarães FS. Lack of effects of clomipramine on Fos and NADPH-diaphorase double-staining in the periaqueductal gray after exposure to an innate fear stimulus. Physiology & Behavior. 94: 316-21. PMID 18321538 DOI: 10.1016/J.Physbeh.2008.01.015  0.408
2008 Resstel LB, Corrêa FM, Guimarães FS. The expression of contextual fear conditioning involves activation of an NMDA receptor-nitric oxide pathway in the medial prefrontal cortex. Cerebral Cortex (New York, N.Y. : 1991). 18: 2027-35. PMID 18158326 DOI: 10.1093/Cercor/Bhm232  0.808
2008 Leite JV, Guimarães FS, Moreira FA. Aripiprazole, an atypical antipsychotic, prevents the motor hyperactivity induced by psychotomimetics and psychostimulants in mice. European Journal of Pharmacology. 578: 222-7. PMID 18021764 DOI: 10.1016/J.Ejphar.2007.09.016  0.376
2008 Lima VCF, Molchanov ML, Aguiar DC, Campos AC, Guimarães FS. Modulation of defensive responses and anxiety-like behaviors by group I metabotropic glutamate receptors located in the dorsolateral periaqueductal gray Progress in Neuro-Psychopharmacology and Biological Psychiatry. 32: 178-185. PMID 17804134 DOI: 10.1016/J.Pnpbp.2007.08.006  0.441
2008 Guimarães FS, Carobrez AP, Graeff FG. Chapter 4.3 Modulation of anxiety behaviors by 5-HT-interacting drugs Handbook of Behavioral Neuroscience. 17: 241-268. DOI: 10.1016/S1569-7339(07)00012-4  0.349
2008 Pelosi G, Resstel L, De Paula Soares V, Zangrossi H, Guimarães F, Corrêa F. P.4.d.004 Anxiolytic-like effects induced by noradrenaline microinjected into the dorsal periaqueductal gray of rats European Neuropsychopharmacology. 18: S496-S497. DOI: 10.1016/S0924-977X(08)70744-2  0.712
2008 Resstel L, Alves F, Reis D, Crestani C, Corrêa F, Guimarães F. P.1.c.036 Anxiolytic-like effects induced by acute reversible inactivation of the bed nucleus of stria terminalis European Neuropsychopharmacology. 18: S240. DOI: 10.1016/S0924-977X(08)70300-6  0.698
2007 Spiacci A, Kanamaru F, Guimarães FS, Oliveira RM. Nitric oxide-mediated anxiolytic-like and antidepressant-like effects in animal models of anxiety and depression. Pharmacology, Biochemistry, and Behavior. 88: 247-55. PMID 17915303 DOI: 10.1016/J.Pbb.2007.08.008  0.327
2007 Resstel LB, Souza RF, Guimarães FS. Anxiolytic-like effects induced by medial prefrontal cortex inhibition in rats submitted to the Vogel conflict test. Physiology & Behavior. 93: 200-5. PMID 17884112 DOI: 10.1016/J.Physbeh.2007.08.009  0.751
2007 Joca SR, Ferreira FR, Guimarães FS. Modulation of stress consequences by hippocampal monoaminergic, glutamatergic and nitrergic neurotransmitter systems. Stress (Amsterdam, Netherlands). 10: 227-49. PMID 17613938 DOI: 10.1080/10253890701223130  0.429
2007 Joca SR, Guimarães FS, Del-Bel E. Inhibition of nitric oxide synthase increases synaptophysin mRNA expression in the hippocampal formation of rats. Neuroscience Letters. 421: 72-6. PMID 17548163 DOI: 10.1016/J.Neulet.2007.05.026  0.361
2006 Moreira FA, Aguiar DC, Guimarães FS. Anxiolytic-like effect of cannabinoids injected into the rat dorsolateral periaqueductal gray. Neuropharmacology. 52: 958-65. PMID 17156799 DOI: 10.1016/J.Neuropharm.2006.10.013  0.503
2006 Lino-de-Oliveira C, de Oliveira RM, Pádua Carobrez A, de Lima TC, del Bel EA, Guimarães FS. Antidepressant treatment reduces Fos-like immunoreactivity induced by swim stress in different columns of the periaqueductal gray matter. Brain Research Bulletin. 70: 414-21. PMID 17027777 DOI: 10.1016/J.Brainresbull.2006.07.007  0.433
2006 Bertoglio LJ, Joca SR, Guimarães FS. Further evidence that anxiety and memory are regionally dissociated within the hippocampus. Behavioural Brain Research. 175: 183-8. PMID 16996146 DOI: 10.1016/J.Bbr.2006.08.021  0.337
2006 Bertoglio LJ, Guimarães FS, Zangrossi H. Lack of interaction between NMDA and cholecystokinin-2 receptor-mediated neurotransmission in the dorsolateral periaqueductal gray in the regulation of rat defensive behaviors. Life Sciences. 79: 2238-44. PMID 16914165 DOI: 10.1016/J.Lfs.2006.07.022  0.423
2006 Moreira FA, Aguiar DC, Guimarães FS. Anxiolytic-like effect of cannabidiol in the rat Vogel conflict test. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 30: 1466-71. PMID 16876926 DOI: 10.1016/J.Pnpbp.2006.06.004  0.42
2006 Resstel LB, Joca SR, Moreira FA, Corrêa FM, Guimarães FS. Effects of cannabidiol and diazepam on behavioral and cardiovascular responses induced by contextual conditioned fear in rats. Behavioural Brain Research. 172: 294-8. PMID 16780966 DOI: 10.1016/J.Bbr.2006.05.016  0.803
2006 Beijamini V, Guimarães FS. Activation of neurons containing the enzyme nitric oxide synthase following exposure to an elevated plus maze. Brain Research Bulletin. 69: 347-55. PMID 16624665 DOI: 10.1016/J.Brainresbull.2006.02.006  0.356
2006 Joca SR, Zanelati T, Guimarães FS. Post-stress facilitation of serotonergic, but not noradrenergic, neurotransmission in the dorsal hippocampus prevents learned helplessness development in rats. Brain Research. 1087: 67-74. PMID 16624257 DOI: 10.1016/J.Brainres.2006.03.034  0.41
2006 Zuardi AW, Crippa JA, Hallak JE, Moreira FA, Guimarães FS. Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 39: 421-9. PMID 16612464 DOI: 10.1590/S0100-879X2006000400001  0.58
2006 Beijamini V, Guimarães FS. c-Fos expression increase in NADPH-diaphorase positive neurons after exposure to a live cat. Behavioural Brain Research. 170: 52-61. PMID 16546272 DOI: 10.1016/J.Bbr.2006.01.025  0.366
2006 Aguiar DC, Moreira FA, Guimarães FS. Flight reactions induced by injection of glutamate N-methyl-d-aspartate receptor agonist into the rat dorsolateral periaqueductal gray are not dependent on endogenous nitric oxide. Pharmacology, Biochemistry, and Behavior. 83: 296-301. PMID 16546244 DOI: 10.1016/J.Pbb.2006.02.010  0.393
2006 Joca SR, Guimarães FS. Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressant-like effects. Psychopharmacology. 185: 298-305. PMID 16518647 DOI: 10.1007/S00213-006-0326-2  0.382
2006 Salum C, Guimarães FS, Brandão ML, Del Bel EA. Dopamine and nitric oxide interaction on the modulation of prepulse inhibition of the acoustic startle response in the Wistar rat. Psychopharmacology. 185: 133-41. PMID 16402193 DOI: 10.1007/S00213-005-0277-Z  0.341
2005 Forestiero D, Manfrim CM, Guimarães FS, de Oliveira RM. Anxiolytic-like effects induced by nitric oxide synthase inhibitors microinjected into the medial amygdala of rats. Psychopharmacology. 184: 166-72. PMID 16362401 DOI: 10.1007/S00213-005-0270-6  0.393
2005 Rosa ML, Silva RC, Moura-de-Carvalho FT, Brandão ML, Guimarães FS, Del Bel EA. Routine post-weaning handling of rats prevents isolation rearing-induced deficit in prepulse inhibition. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 38: 1691-6. PMID 16258640 DOI: 10.1590/S0100-879X2005001100018  0.335
2005 Jardim MC, Aguiar DC, Moreira FA, Guimarães FS. Role of glutamate ionotropic and benzodiazepine receptors in the ventromedial hypothalamic nucleus on anxiety. Pharmacology, Biochemistry and Behavior. 82: 182-189. PMID 16153701 DOI: 10.1016/J.Pbb.2005.08.006  0.446
2005 Graeff FG, Garcia-Leal C, Del-Ben CM, Guimarães FS. Does the panic attack activate the hypothalamic-pituitary-adrenal axis? Anais Da Academia Brasileira De CiãªNcias. 77: 477-91. PMID 16127553 DOI: 10.1590/S0001-37652005000300009  0.371
2005 Guimarães FS, Beijamini V, Moreira FA, Aguiar DC, Lucca ACBd. Role of nitric oxide in brain regions related to defensive reactions. Neuroscience & Biobehavioral Reviews. 29: 1313-1322. PMID 16095696 DOI: 10.1016/J.Neubiorev.2005.03.026  0.415
2005 Del Bel EA, Guimarães FS, Bermúdez-Echeverry M, Gomes MZ, Schiaveto-de-souza A, Padovan-Neto FE, Tumas V, Barion-Cavalcanti AP, Lazzarini M, Nucci-da-Silva LP, de Paula-Souza D. Role of nitric oxide on motor behavior. Cellular and Molecular Neurobiology. 25: 371-92. PMID 16047547 DOI: 10.1007/S10571-005-3065-8  0.395
2005 Moreira FA, Guimarães FS. Role of serotonin receptors in panic-like behavior induced by nitric oxide in the rat dorsolateral periaqueductal gray: effects of chronic clomipramine treatment. Life Sciences. 77: 1972-82. PMID 15916775 DOI: 10.1016/J.Lfs.2005.02.016  0.447
2005 Moreira FA, Guimarães FS. Cannabidiol inhibits the hyperlocomotion induced by psychotomimetic drugs in mice. European Journal of Pharmacology. 512: 199-205. PMID 15840405 DOI: 10.1016/J.Ejphar.2005.02.040  0.36
2005 Rosa ML, Guimarães FS, de Oliveira RM, Padovan CM, Pearson RC, Del Bel EA. Restraint stress induces beta-amyloid precursor protein mRNA expression in the rat basolateral amygdala. Brain Research Bulletin. 65: 69-75. PMID 15680546 DOI: 10.1016/J.Brainresbull.2004.11.011  0.365
2005 Jardim MC, Guimarães FS. Role of glutamate ionotropic receptors in the dorsomedial hypothalamic nucleus on anxiety and locomotor behavior. Pharmacology, Biochemistry, and Behavior. 79: 541-6. PMID 15582026 DOI: 10.1016/J.Pbb.2004.09.005  0.458
2005 Zanoveli JM, Netto CF, Guimarães FS, Zangrossi H. Systemic and intra-dorsal periaqueductal gray injections of cholecystokinin sulfated octapeptide (CCK-8s) induce a panic-like response in rats submitted to the elevated T-maze. Peptides. 25: 1935-41. PMID 15501525 DOI: 10.1016/J.Peptides.2004.06.016  0.436
2004 Moreira FA, Guimarães FS. Benzodiazepine receptor and serotonin 2A receptor modulate the aversive-like effects of nitric oxide in the dorsolateral periaqueductal gray of rats. Psychopharmacology. 176: 362-8. PMID 15278346 DOI: 10.1007/S00213-004-1910-Y  0.406
2004 Guimarães VMC, Zuardi AW, Del Bel EA, Guimarães FS. Cannabidiol increases Fos expression in the nucleus accumbens but not in the dorsal striatum Life Sciences. 75: 633-638. PMID 15158372 DOI: 10.1016/J.Lfs.2004.01.015  0.565
2004 Echeverry MB, Guimarães FS, Del Bel EA. Acute and delayed restraint stress-induced changes in nitric oxide producing neurons in limbic regions. Neuroscience. 125: 981-93. PMID 15120858 DOI: 10.1016/J.Neuroscience.2003.12.046  0.348
2004 Crippa JA, Uchida R, Busatto GF, Guimarães FS, Del-Ben CM, Zuardi AW, Santos AC, Araújo D, McGuire PK, Graeff FG. The size and prevalence of the cavum septum pellucidum are normal in subjects with panic disorder. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 37: 371-4. PMID 15060705 DOI: 10.1590/S0100-879X2004000300013  0.514
2004 Joca SR, Padovan CM, Guimarães FS. [Stress, depression and the hippocampus]. Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999). 46-51. PMID 14978587 DOI: 10.1590/S1516-44462003000600011  0.388
2004 Del Bel EA, da Silva CA, Guimarães FS, Bermúdez-Echeverry M. Catalepsy induced by intra-striatal administration of nitric oxide synthase inhibitors in rats. European Journal of Pharmacology. 485: 175-81. PMID 14757138 DOI: 10.1016/J.Ejphar.2003.11.071  0.308
2004 Padovan CM, Guimarães FS. Antidepressant-like effects of NMDA-receptor antagonist injected into the dorsal hippocampus of rats. Pharmacology, Biochemistry, and Behavior. 77: 15-9. PMID 14724037 DOI: 10.1016/J.Pbb.2003.09.015  0.442
2004 Andrade CS, Guimarães FS. Anxiolytic-like effect of group housing on stress-induced behavior in rats. Depression and Anxiety. 18: 149-52. PMID 14625880 DOI: 10.1002/Da.10124  0.374
2004 Netto CF, Guimarães FS. Anxiogenic effect of cholecystokinin in the dorsal periaqueductal gray. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 101-7. PMID 14583742 DOI: 10.1038/Sj.Npp.1300334  0.4
2004 de Araújo Moreira F, Molchanov ML, Guimarães FS. Flight reactions to nitric oxide in the inferior colliculus of rats depend on NMDA receptor activation. Pharmacology, Biochemistry, and Behavior. 76: 35-41. PMID 13679215 DOI: 10.1016/S0091-3057(03)00186-2  0.373
2003 Moreira FA, Molchanov ML, Guimarães FS. Ionotropic glutamate-receptor antagonists inhibit the aversive effects of nitric oxide donor injected into the dorsolateral periaqueductal gray of rats. Psychopharmacology. 171: 199-203. PMID 12955288 DOI: 10.1007/S00213-003-1569-9  0.352
2003 Joca SR, Padovan CM, Guimarães FS. Activation of post-synaptic 5-HT(1A) receptors in the dorsal hippocampus prevents learned helplessness development. Brain Research. 978: 177-84. PMID 12834912 DOI: 10.1016/S0006-8993(03)02943-3  0.392
2003 Graeff FG, Parente A, Del-Ben CM, Guimarães FS. Pharmacology of human experimental anxiety. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 36: 421-32. PMID 12700819 DOI: 10.1590/S0100-879X2003000400003  0.355
2003 Netto SM, Silveira R, Coimbra NC, Joca SR, Guimarães FS. Anxiogenic effect of median raphe nucleus lesion in stressed rats. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 26: 1135-41. PMID 12452536 DOI: 10.1016/S0278-5846(02)00248-8  0.373
2003 Crippa J, Zuardi A, Busatto G, Hallak J, Sanches R, Santos A, Guimaraes F, Araujo D, Allen P, McGuire P. Clinical and psychophysiology correlates of a large cavum septum pellucidum in schizophrenia Schizophrenia Research. 60: 192. DOI: 10.1016/S0920-9964(03)81104-0  0.473
2002 Lopes-Machado EZ, De Souza Crippa JA, Hallak JEC, Guimarães FS, Zuardi AW. Electrodermically nonresponsive schizophrenia patients make more errors in the stroop color word test, indicating selective attention deficit Schizophrenia Bulletin. 28: 459-466. PMID 12645677 DOI: 10.1093/Oxfordjournals.Schbul.A006953  0.508
2002 Del-Bel EA, Joca SR, Padovan CM, Guimarães FS. Effects of isolation-rearing on serotonin-1A and M1-muscarinic receptor messenger RNA expression in the hipocampal formation of rats. Neuroscience Letters. 332: 123-6. PMID 12384226 DOI: 10.1016/S0304-3940(02)00933-3  0.34
2002 Rosa ML, Guimarães FS, Pearson RC, Del Bel EA. Effects of single or repeated restraint stress on GluR1 and GluR2 flip and flop mRNA expression in the hippocampal formation. Brain Research Bulletin. 59: 117-24. PMID 12379442 DOI: 10.1016/S0361-9230(02)00859-6  0.33
2002 Echeverry MB, Guimarães FS, Oliveira MA, do Prado WA, Del Bel EA. Delayed stress-induced antinociceptive effect of nitric oxide synthase inhibition in the dentate gyrus of rats. Pharmacology, Biochemistry, and Behavior. 74: 149-56. PMID 12376162 DOI: 10.1016/S0091-3057(02)00964-4  0.391
2002 Del Bel EA, Souza AS, Guimarães FS, da-Silva CA, Nucci-da-Silva LP. Motor effects of acute and chronic inhibition of nitric oxide synthesis in mice. Psychopharmacology. 161: 32-7. PMID 11967628 DOI: 10.1007/S00213-002-1009-2  0.329
2002 De Oliveira RM, Del Bel EA, Guimarães FS. Effects of excitatory amino acids and nitric oxide on flight behavior elicited from the dorsolateral periaqueductal gray. Neuroscience and Biobehavioral Reviews. 25: 679-85. PMID 11801293 DOI: 10.1016/S0149-7634(01)00050-1  0.407
2001 Graeff FG, Silva M, Del Ben CM, Zuardi AW, Hetem LA, Guimarães FS. Comparison between two models of experimental anxiety in healthy volunteers and panic disorder patients. Neuroscience and Biobehavioral Reviews. 25: 753-9. PMID 11801299 DOI: 10.1016/S0149-7634(01)00055-0  0.556
2001 Del-Ben CM, Vilela JA, Hetem LA, Guimarães FS, Graeff FG, Zuardi AW. Do panic patients process unconditioned fear vs. conditioned anxiety differently than normal subjects? Psychiatry Research. 104: 227-37. PMID 11728612 DOI: 10.1016/S0165-1781(01)00312-2  0.529
2001 Lino-de-Oliveira C, Sales AJ, Del Bel EA, Silveira MC, Guimarães FS. Effects of acute and chronic fluoxetine treatments on restraint stress-induced Fos expression. Brain Research Bulletin. 55: 747-54. PMID 11595358 DOI: 10.1016/S0361-9230(01)00566-4  0.402
2001 Jardim MC, Guimarães FS. GABAergic and glutamatergic modulation of exploratory behavior in the dorsomedial hypothalamus. Pharmacology, Biochemistry, and Behavior. 69: 579-84. PMID 11509219 DOI: 10.1016/S0091-3057(01)00560-3  0.453
2001 Silva M, Hetem LA, Guimarães FS, Graeff FG. Opposite effects of nefazodone in two human models of anxiety. Psychopharmacology. 156: 454-60. PMID 11498723 DOI: 10.1007/S002130100752  0.381
2001 Andreatini R, Blanchard C, Blanchard R, Brandão ML, Carobrez AP, Griebel G, Guimarães FS, Handley SL, Jenck F, Leite JR, Rodgers J, Schenberg LC, Da Cunha C, Graeff FG. The brain decade in debate: II. Panic or anxiety? From animal models to a neurobiological basis. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 34: 145-54. PMID 11175489 DOI: 10.1590/S0100-879X2001000200001  0.341
2001 Padovan CM, Del Bel EA, Guimarães FS. Behavioral effects in the elevated plus maze of an NMDA antagonist injected into the dorsal hippocampus: influence of restraint stress. Pharmacology, Biochemistry, and Behavior. 67: 325-30. PMID 11124397 DOI: 10.1016/S0091-3057(00)00361-0  0.43
2000 de Oliveira RM, Aparecida Del Bel E, Mamede-Rosa ML, Padovan CM, Deakin JF, Guimarães FS. Expression of neuronal nitric oxide synthase mRNA in stress-related brain areas after restraint in rats. Neuroscience Letters. 289: 123-6. PMID 10904135 DOI: 10.1016/S0304-3940(00)01287-8  0.359
2000 Ponzoni S, Guimarães FS, Del Bel EA, Garcia-Cairasco N. Behavioral effects of intra-nigral microinjections of manganese chloride: interaction with nitric oxide. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 24: 307-25. PMID 10800753 DOI: 10.1016/S0278-5846(99)00090-1  0.35
2000 Monteiro-dos-Santos PC, Graeff FG, dos-Santos JE, Ribeiro RP, Guimarães FS, Zuardi AW. Effects of tryptophan depletion on anxiety induced by simulated public speaking. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De Biofã­Sica ... [Et Al.]. 33: 581-7. PMID 10775890 DOI: 10.1590/S0100-879X2000000500013  0.555
2000 Guimarães AP, Guimarães FS, Prado WA. Modulation of carbachol-induced antinociception from the rat periaqueductal gray. Brain Research Bulletin. 51: 471-8. PMID 10758336 DOI: 10.1016/S0361-9230(99)00266-X  0.354
2000 de Oliveira RW, Del Bel EA, Guimarães FS. Behavioral and c-fos expression changes induced by nitric oxide donors microinjected into the dorsal periaqueductal gray. Brain Research Bulletin. 51: 457-64. PMID 10758334 DOI: 10.1016/S0361-9230(99)00248-8  0.438
2000 Bel EAD, Guimarães FS. Sub-chronic inhibition of nitric-oxide synthesis modifies haloperidol-induced catalepsy and the number of NADPH-diaphorase neurons in mice. Psychopharmacology. 147: 356-361. PMID 10672628 DOI: 10.1007/S002130050003  0.356
2000 Padovan CM, Guimarães FS. Restraint-induced hypoactivity in an elevated plus-maze. Brazilian Journal of Medical and Biological Research. 33: 79-83. PMID 10625878 DOI: 10.1590/S0100-879X2000000100011  0.349
1999 Nucci-da-Silva LP, Guimarães FS, Bel EAD. Serotonin modulation of catalepsy induced by NG-nitro-l-arginine in mice European Journal of Pharmacology. 379: 47-52. PMID 10499370 DOI: 10.1016/S0014-2999(99)00493-8  0.336
1999 Hellewell JS, Guimaraes FS, Wang M, Deakin JF. Comparison of buspirone with diazepam and fluvoxamine on aversive classical conditioning in humans. Journal of Psychopharmacology (Oxford, England). 13: 122-7. PMID 10475716 DOI: 10.1177/026988119901300202  0.337
1999 Garcia-Cairasco N, Oliveira JA, Wakamatsu H, Bueno ST, Guimarães FS. Reduced exploratory activity of audiogenic seizures susceptible Wistar rats. Physiology & Behavior. 64: 671-4. PMID 9817579 DOI: 10.1016/S0031-9384(98)00129-2  0.319
1998 Del Bel EA, Silveira MC, Graeff FG, Garcia-Cairasco N, Guimarães FS. Differential expression of c-fos mRNA and Fos protein in the rat brain after restraint stress or pentylenetetrazol-induced seizures. Cellular and Molecular Neurobiology. 18: 339-46. PMID 9590563 DOI: 10.1023/A:1022505232618  0.321
1998 Mendonça FH, Guimarães FS. Intra-hippocampal administration of cycloheximide attenuates the restraint-induced exploratory deficit of an elevated plus maze. Behavioural Brain Research. 91: 207-11. PMID 9580415 DOI: 10.1016/S0166-4328(97)00129-0  0.376
1997 Martins AP, Marras RA, Guimarães FS. Anxiogenic effect of corticotropin-releasing hormone in the dorsal periaqueductal grey. Neuroreport. 8: 3601-3604. PMID 9427334 DOI: 10.1097/00001756-199711100-00036  0.327
1997 Bel EAD, Guimaraes FS. Social isolation increases cholecystokinin mRNA in the central nervous system of rats. Neuroreport. 8: 3597-3600. PMID 9427333 DOI: 10.1097/00001756-199711100-00035  0.31
1997 Guimarães FS, Mbaya PS, Deakin JF. Ritanserin facilitates anxiety in a simulated public-speaking paradigm Journal of Psychopharmacology. 11: 225-231. PMID 9305414 DOI: 10.1177/026988119701100305  0.328
1997 Matheus MG, Guimarães FS. Antagonism of non-NMDA receptors in the dorsal periaqueductal grey induces anxiolytic effect in the elevated plus maze. Psychopharmacology. 132: 14-8. PMID 9272754 DOI: 10.1007/S002130050314  0.437
1997 Lino de Oliveira C, Guimarães FS, Del Bel EA. c-jun mRNA expression in the hippocampal formation induced by restraint stress. Brain Research. 753: 202-8. PMID 9125404 DOI: 10.1016/S0006-8993(96)01490-4  0.37
1997 De Oliveira CL, Del Bel EA, Guimarães FS. Effects of L-NOARG on plus-maze performance in rats. Pharmacology, Biochemistry, and Behavior. 56: 55-9. PMID 8981609 DOI: 10.1016/S0091-3057(96)00156-6  0.35
1996 Graeff FG, Guimarães FS, De Andrade TG, Deakin JF. Role of 5-HT in stress, anxiety, and depression. Pharmacology, Biochemistry, and Behavior. 54: 129-41. PMID 8728550 DOI: 10.1016/0091-3057(95)02135-3  0.385
1996 Hetem LAB, de Souza CJ, Zuardi AW, Guimarães FS, Graeff FG. Effect ofd-fenfluramine on human experimental anxiety Psychopharmacology. 127: 276-282. DOI: 10.1007/BF02246136  0.462
1995 Titze-de-Almeida R, de Oliveira CL, Shida HW, Guimarães FS, Del Bel EA. Midazolam and the N-methyl-D-aspartate (NMDA) receptor antagonist 2-amino-7-phosphonoheptanoic acid (AP-7) attenuate stress-induced expression of c-fos mRNA in the dentate gyrus. Cellular and Molecular Neurobiology. 14: 373-80. PMID 7788644 DOI: 10.1007/Bf02088717  0.364
1994 Guimarães FS, Del Bel EA, Padovan CM, Netto SM, de Almeida RT. Hippocampal 5-HT receptors and consolidation of stressful memories. Behavioural Brain Research. 58: 133-9. PMID 8136041 DOI: 10.1016/0166-4328(93)90098-B  0.408
1994 Matheus MG, Nogueira RL, Carobrez AP, Graeff FG, Guimarães FS. Anxiolytic effect of glycine antagonists microinjected into the dorsal periaqueductal grey. Psychopharmacology. 113: 565-9. PMID 7862877 DOI: 10.1007/Bf02245241  0.427
1993 Zuardi AW, Cosme RA, Graeff FG, Guimarães FS. Effects of ipsapirone and cannabidiol on human experimental anxiety. Journal of Psychopharmacology (Oxford, England). 7: 82-8. PMID 22290374 DOI: 10.1177/026988119300700112  0.567
1993 de Souza Silva M, Guimarães FS, Graeff FG, Tomaz C. Absence of amnestic effect of an anxiolytic 5-HT3 antagonist (BRL 46470A) injected into basolateral amygdala, as opposed to diazepam. Behavioural Brain Research. 59: 141-5. PMID 8155281 DOI: 10.1016/0166-4328(93)90160-R  0.358
1993 Russo AS, Guimarães FS, De Aguiar JC, Graeff FG. Role of benzodiazepine receptors located in the dorsal periaqueductal grey of rats in anxiety. Psychopharmacology. 110: 198-202. PMID 7870885 DOI: 10.1007/Bf02246973  0.452
1991 Hensman R, Guimarães FS, Wang M, Deakin JF. Effects of ritanserin on aversive classical conditioning in humans. Psychopharmacology. 104: 220-4. PMID 1908584 DOI: 10.1007/Bf02244182  0.339
1991 Guimarães FS, Hellewell J, Hensman R, Wang M, Deakin JF. Characterization of a psychophysiological model of classical fear conditioning in healthy volunteers: influence of gender, instruction, personality and placebo. Psychopharmacology. 104: 231-6. PMID 1876667 DOI: 10.1007/Bf02244184  0.303
1991 Guimarães FS, Carobrez AP, De Aguiar JC, Graeff FG. Anxiolytic effect in the elevated plus-maze of the NMDA receptor antagonist AP7 microinjected into the dorsal periaqueductal grey. Psychopharmacology. 103: 91-4. PMID 1672463 DOI: 10.1007/Bf02244080  0.389
1990 Guimarães FS, Chiaretti TM, Graeff FG, Zuardi AW. Antianxiety effect of cannabidiol in the elevated plus-maze. Psychopharmacology. 100: 558-9. PMID 1969666 DOI: 10.1007/Bf02244012  0.564
1987 Guimarães FS, Zuardi AW, Graeff FG. Effect of chlorimipramine and maprotiline on experimental anxiety in humans. Journal of Psychopharmacology (Oxford, England). 1: 184-92. PMID 22158980 DOI: 10.1177/026988118700100305  0.574
Show low-probability matches.