Michael J. Zuscik - Publications

Affiliations: 
School of Medicine and Dentistry University of Rochester, Rochester, NY 
Area:
Toxicology, Public Health

77 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Catheline SE, Hoak D, Chang M, Ketz JP, Hilton MJ, Zuscik MJ, Jonason JH. Chondrocyte-Specific RUNX2 Overexpression Accelerates Post-traumatic Osteoarthritis Progression in Adult Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 31189030 DOI: 10.1002/Jbmr.3737  0.391
2018 Wang W, Lin X, Xu H, Sun W, Bouta EM, Zuscik MJ, Chen D, Schwarz EM, Xing L. Bortezomib Attenuates Joint Tissue Damage in a Mouse Model of Experimental Post-Traumatic Osteoarthritis, which is Associated with Improved Synovial Lymphatic Function. Arthritis & Rheumatology (Hoboken, N.J.). PMID 30144298 DOI: 10.1002/Art.40696  0.309
2017 Farnsworth CW, Schott EM, Benvie AM, Zukoski J, Kates SL, Schwarz EM, Gill SR, Zuscik MJ, Mooney RA. Obesity/type 2 diabetes increases inflammation, periosteal reactive bone formation and osteolysis during Staphylococcus aureus implant-associated bone infection. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 29227579 DOI: 10.1002/Jor.23831  0.311
2017 Shen J, Wang C, Li D, Xu T, Myers J, Ashton JM, Wang T, Zuscik MJ, McAlinden A, O'Keefe RJ. DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism. Jci Insight. 2. PMID 28614801 DOI: 10.1172/Jci.Insight.93612  0.349
2017 Dar QA, Schott EM, Catheline SE, Maynard RD, Liu Z, Kamal F, Farnsworth CW, Ketz JP, Mooney RA, Hilton MJ, Jonason JH, Prawitt J, Zuscik MJ. Daily oral consumption of hydrolyzed type 1 collagen is chondroprotective and anti-inflammatory in murine posttraumatic osteoarthritis. Plos One. 12: e0174705. PMID 28384173 DOI: 10.1371/Journal.Pone.0174705  0.36
2017 Farnsworth CW, Schott EM, Jensen SE, Zukoski J, Benvie AM, Refaai MA, Kates SL, Schwarz EM, Zuscik MJ, Gill SR, Mooney RA. Adaptive upregulation of Clumping Factor A (ClfA) by S. aureus in the obese, type 2 diabetic host mediates increased virulence. Infection and Immunity. PMID 28320836 DOI: 10.1128/Iai.01005-16  0.307
2017 Kelly M, Loiselle A, Zuscik M, Giordano BD. Estrogen Deprivation and Diet-Induced Obesity Result in Alterations in Bone and Cartilage Content in the Murine Hip Orthopaedic Journal of Sports Medicine. 5: 2325967117S0041. DOI: 10.1177/2325967117S00413  0.326
2017 Kamal F, Schott EM, Carlson EL, El-Quadi M, Bleu HKL, Hilton MJ, Jonason JH, Zuscik MJ. Chondrocyte PTH1R anti-hypertrophic signaling is essential for articular cartilage maintenance and protection post trauma Osteoarthritis and Cartilage. 25. DOI: 10.1016/J.Joca.2017.02.037  0.355
2016 Zingman A, Li H, Sundem L, DeHority B, Geary M, Fussel T, Mooney R, Zuscik M, Elfar J. Shoulder arthritis secondary to rotator cuff tear: A reproducible murine model and histopathologic scoring system. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 27500994 DOI: 10.1002/Jor.23383  0.313
2015 Kohn A, Rutkowski TP, Liu Z, Mirando AJ, Zuscik MJ, O'Keefe RJ, Hilton MJ. Notch signaling controls chondrocyte hypertrophy via indirect regulation of Sox9. Bone Research. 3: 15021. PMID 26558140 DOI: 10.1038/Boneres.2015.21  0.375
2015 Liu Z, Ren Y, Mirando AJ, Wang C, Zuscik MJ, O'Keefe RJ, Hilton MJ. Notch Signaling in Postnatal Joint Chondrocytes, but not Subchondral Osteoblasts, is Required for Articular Cartilage and Joint Maintenance. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. PMID 26522700 DOI: 10.1016/J.Joca.2015.10.015  0.373
2015 Zhang Y, Sheu TJ, Hoak D, Shen J, Hilton MJ, Zuscik MJ, Jonason JH, O'Keefe RJ. CCN1 Regulates Chondrocyte Maturation and Cartilage Development. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26363286 DOI: 10.1002/Jbmr.2712  0.446
2015 Liu Z, Chen J, Mirando AJ, Wang C, Zuscik MJ, O'Keefe RJ, Hilton MJ. A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis. Science Signaling. 8: ra71. PMID 26198357 DOI: 10.1016/J.Joca.2015.02.133  0.4
2015 Shu L, Beier E, Sheu T, Zhang H, Zuscik MJ, Puzas EJ, Boyce BF, Mooney RA, Xing L. High-fat diet causes bone loss in young mice by promoting osteoclastogenesis through alteration of the bone marrow environment. Calcified Tissue International. 96: 313-23. PMID 25673503 DOI: 10.1007/S00223-015-9954-Z  0.332
2014 Sheu TJ, Zhou W, Fan J, Zhou H, Zuscik MJ, Xie C, Yin G, Berk BC. Decreased BMP2 signal in GIT1 knockout mice slows bone healing. Molecular and Cellular Biochemistry. 397: 67-74. PMID 25138700 DOI: 10.1007/S11010-014-2173-5  0.404
2014 Beier EE, Sheu TJ, Buckley T, Yukata K, O'Keefe R, Zuscik MJ, Puzas JE. Inhibition of beta-catenin signaling by Pb leads to incomplete fracture healing. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 32: 1397-405. PMID 25044211 DOI: 10.1002/Jor.22677  0.38
2014 Yin G, Sheu TJ, Menon P, Pang J, Ho HC, Shi S, Xie C, Smolock E, Yan C, Zuscik MJ, Berk BC. Impaired angiogenesis during fracture healing in GPCR kinase 2 interacting protein-1 (GIT1) knock out mice. Plos One. 9: e89127. PMID 24586541 DOI: 10.1371/Journal.Pone.0089127  0.348
2014 Shi J, Liang Q, Zuscik M, Shen J, Chen D, Xu H, Wang YJ, Chen Y, Wood RW, Li J, Boyce BF, Xing L. Distribution and alteration of lymphatic vessels in knee joints of normal and osteoarthritic mice. Arthritis & Rheumatology (Hoboken, N.J.). 66: 657-66. PMID 24574226 DOI: 10.1002/Art.38278  0.344
2014 Hamada D, Sampson ER, Maynard RD, Zuscik MJ. Surgical induction of posttraumatic osteoarthritis in the mouse. Methods in Molecular Biology (Clifton, N.J.). 1130: 61-72. PMID 24482165 DOI: 10.1007/978-1-62703-989-5_5  0.319
2013 Gao L, Sheu TJ, Dong Y, Hoak DM, Zuscik MJ, Schwarz EM, Hilton MJ, O'Keefe RJ, Jonason JH. TAK1 regulates SOX9 expression in chondrocytes and is essential for postnatal development of the growth plate and articular cartilages. Journal of Cell Science. 126: 5704-13. PMID 24144697 DOI: 10.1242/Jcs.135483  0.457
2013 Inzana JA, Kung M, Shu L, Hamada D, Xing LP, Zuscik MJ, Awad HA, Mooney RA. Immature mice are more susceptible to the detrimental effects of high fat diet on cancellous bone in the distal femur. Bone. 57: 174-83. PMID 23954757 DOI: 10.1016/J.Bone.2013.08.003  0.317
2013 Mirando AJ, Liu Z, Moore T, Lang A, Kohn A, Osinski AM, O'Keefe RJ, Mooney RA, Zuscik MJ, Hilton MJ. RBP-Jκ-dependent Notch signaling is required for murine articular cartilage and joint maintenance. Arthritis and Rheumatism. 65: 2623-33. PMID 23839930 DOI: 10.1002/Art.38076  0.393
2013 Beier EE, Maher JR, Sheu TJ, Cory-Slechta DA, Berger AJ, Zuscik MJ, Puzas JE. Heavy metal lead exposure, osteoporotic-like phenotype in an animal model, and depression of Wnt signaling. Environmental Health Perspectives. 121: 97-104. PMID 23086611 DOI: 10.1289/Ehp.1205374  0.334
2013 Dhillon RS, Xie C, Tyler W, Calvi LM, Awad HA, Zuscik MJ, O'Keefe RJ, Schwarz EM. PTH-enhanced structural allograft healing is associated with decreased angiopoietin-2-mediated arteriogenesis, mast cell accumulation, and fibrosis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 586-97. PMID 22991274 DOI: 10.1002/Jbmr.1765  0.341
2012 Holz JD, Beier E, Sheu TJ, Ubayawardena R, Wang M, Sampson ER, Rosier RN, Zuscik M, Puzas JE. Lead induces an osteoarthritis-like phenotype in articular chondrocytes through disruption of TGF-β signaling. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 30: 1760-6. PMID 22517267 DOI: 10.1002/Jor.22117  0.637
2012 Kim KO, Sampson ER, Maynard RD, O'Keefe RJ, Chen D, Drissi H, Rosier RN, Hilton MJ, Zuscik MJ. Ski inhibits TGF-β/phospho-Smad3 signaling and accelerates hypertrophic differentiation in chondrocytes. Journal of Cellular Biochemistry. 113: 2156-66. PMID 22461172 DOI: 10.1002/Jcb.24089  0.388
2012 Wang M, Tang D, Shu B, Wang B, Jin H, Hao S, Dresser KA, Shen J, Im HJ, Sampson ER, Rubery PT, Zuscik MJ, Schwarz EM, O'Keefe RJ, Wang Y, et al. Conditional activation of β-catenin signaling in mice leads to severe defects in intervertebral disc tissue. Arthritis and Rheumatism. 64: 2611-23. PMID 22422036 DOI: 10.1002/Art.34469  0.618
2012 Kohn A, Dong Y, Mirando AJ, Jesse AM, Honjo T, Zuscik MJ, O'Keefe RJ, Hilton MJ. Cartilage-specific RBPjκ-dependent and -independent Notch signals regulate cartilage and bone development. Development (Cambridge, England). 139: 1198-212. PMID 22354840 DOI: 10.1242/Dev.070649  0.406
2012 Kung MH, Yukata K, O'Keefe RJ, Zuscik MJ. Aryl hydrocarbon receptor-mediated impairment of chondrogenesis and fracture healing by cigarette smoke and benzo(a)pyrene. Journal of Cellular Physiology. 227: 1062-70. PMID 21567390 DOI: 10.1002/Jcp.22819  0.323
2011 Wang M, Jin H, Tang D, Huang S, Zuscik MJ, Chen D. Smad1 plays an essential role in bone development and postnatal bone formation Osteoarthritis and Cartilage. 19: 751-762. PMID 21420501 DOI: 10.1016/J.Joca.2011.03.004  0.367
2011 Sampson ER, Beck CA, Ketz J, Canary KL, Hilton MJ, Awad H, Schwarz EM, Chen D, O'Keefe RJ, Rosier RN, Zuscik MJ. Establishment of an index with increased sensitivity for assessing murine arthritis. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 29: 1145-51. PMID 21374709 DOI: 10.1002/Jor.21368  0.328
2011 Jacobson JA, Yanoso-Scholl L, Reynolds DG, Dadali T, Bradica G, Bukata S, Puzas EJ, Zuscik MJ, Rosier R, O'Keefe RJ, Schwarz EM, Awad HA. Teriparatide therapy and beta-tricalcium phosphate enhance scaffold reconstruction of mouse femoral defects. Tissue Engineering. Part A. 17: 389-98. PMID 20807012 DOI: 10.1089/Ten.Tea.2010.0115  0.346
2011 Mirando AJ, Moore T, Lang A, Jesse AM, Kohn A, Zuscik MJ, O'Keefe RJ, Hilton MJ. 70 Rbpjk-Dependent Notch Signaling Is Required For Articular Cartilage And Joint Maintenance Osteoarthritis and Cartilage. 19. DOI: 10.1016/S1063-4584(11)60097-6  0.36
2010 Yanoso-Scholl L, Jacobson JA, Bradica G, Lerner AL, O'Keefe RJ, Schwarz EM, Zuscik MJ, Awad HA. Evaluation of dense polylactic acid/beta-tricalcium phosphate scaffolds for bone tissue engineering. Journal of Biomedical Materials Research. Part A. 95: 717-26. PMID 20725979 DOI: 10.1002/Jbm.A.32868  0.334
2010 Menon P, Yin G, Smolock EM, Zuscik MJ, Yan C, Berk BC. GPCR kinase 2 interacting protein 1 (GIT1) regulates osteoclast function and bone mass. Journal of Cellular Physiology. 225: 777-85. PMID 20568227 DOI: 10.1002/Jcp.22282  0.353
2010 Li TF, Gao L, Sheu TJ, Sampson ER, Flick LM, Konttinen YT, Chen D, Schwarz EM, Zuscik MJ, Jonason JH, O'Keefe RJ. Aberrant hypertrophy in Smad3-deficient murine chondrocytes is rescued by restoring transforming growth factor beta-activated kinase 1/activating transcription factor 2 signaling: a potential clinical implication for osteoarthritis. Arthritis and Rheumatism. 62: 2359-69. PMID 20506210 DOI: 10.1002/Art.27537  0.377
2010 Wu Q, Zhu M, Rosier RN, Zuscik MJ, O'Keefe RJ, Chen D. Beta-catenin, cartilage, and osteoarthritis. Annals of the New York Academy of Sciences. 1192: 344-50. PMID 20392258 DOI: 10.1111/J.1749-6632.2009.05212.X  0.411
2010 Dong Y, Jesse AM, Kohn A, Gunnell LM, Honjo T, Zuscik MJ, O'Keefe RJ, Hilton MJ. RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal development. Development (Cambridge, England). 137: 1461-71. PMID 20335360 DOI: 10.1242/Dev.042911  0.345
2009 Wu Q, Huang JH, Sampson ER, Kim KO, Zuscik MJ, O'Keefe RJ, Chen D, Rosier RN. Smurf2 induces degradation of GSK-3beta and upregulates beta-catenin in chondrocytes: a potential mechanism for Smurf2-induced degeneration of articular cartilage. Experimental Cell Research. 315: 2386-98. PMID 19481076 DOI: 10.1016/J.Yexcr.2009.05.019  0.425
2009 Clark CA, Li TF, Kim KO, Drissi H, Zuscik MJ, Zhang X, O'Keefe RJ. Prostaglandin E2 inhibits BMP signaling and delays chondrocyte maturation. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 27: 785-92. PMID 19023895 DOI: 10.1002/Jor.20805  0.45
2009 Naik AA, Xie C, Zuscik MJ, Kingsley P, Schwarz EM, Awad H, Guldberg R, Drissi H, Puzas JE, Boyce B, Zhang X, O'Keefe RJ. Reduced COX-2 expression in aged mice is associated with impaired fracture healing. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 251-64. PMID 18847332 DOI: 10.1359/Jbmr.081002  0.356
2009 Zhu M, Tang D, Wu Q, Hao S, Chen M, Xie C, Rosier RN, O'Keefe RJ, Zuscik M, Chen D. Activation of beta-catenin signaling in articular chondrocytes leads to osteoarthritis-like phenotype in adult beta-catenin conditional activation mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 24: 12-21. PMID 18767925 DOI: 10.1359/Jbmr.080901  0.398
2008 Wu Q, Kim KO, Sampson ER, Chen D, Awad H, O'Brien T, Puzas JE, Drissi H, Schwarz EM, O'Keefe RJ, Zuscik MJ, Rosier RN. Induction of an osteoarthritis-like phenotype and degradation of phosphorylated Smad3 by Smurf2 in transgenic mice. Arthritis and Rheumatism. 58: 3132-44. PMID 18821706 DOI: 10.1002/Art.23946  0.405
2008 Zhu M, Chen M, Zuscik M, Wu Q, Wang YJ, Rosier RN, O'Keefe RJ, Chen D. Inhibition of beta-catenin signaling in articular chondrocytes results in articular cartilage destruction. Arthritis and Rheumatism. 58: 2053-64. PMID 18576323 DOI: 10.1002/Art.23614  0.409
2008 Zuscik MJ, Hilton MJ, Zhang X, Chen D, O'Keefe RJ. Regulation of chondrogenesis and chondrocyte differentiation by stress. The Journal of Clinical Investigation. 118: 429-38. PMID 18246193 DOI: 10.1172/Jci34174  0.314
2008 Wu Q, Wang M, Zuscik MJ, Chen D, O'Keefe RJ, Rosier RN. Regulation of embryonic endochondral ossification by Smurf2. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 26: 704-12. PMID 18176945 DOI: 10.1002/Jor.20563  0.644
2008 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN. Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 552-63. PMID 18052755 DOI: 10.1359/Jbmr.071115  0.372
2008 Usui M, Xing L, Drissi H, Zuscik M, O'Keefe R, Chen D, Boyce BF. Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 314-25. PMID 17967138 DOI: 10.1359/Jbmr.071025  0.38
2008 Chen D, Zhu M, Tang D, Wu Q, Chen M, Xie C, Rosier R, OKeefe R, Zuscik M. Conditional activation of the β-catenin gene in articular chondrocytes in adult mice leads to osteoarthritis-like phenotype Bone. 43: S27. DOI: 10.1016/J.Bone.2008.07.024  0.335
2007 Dao DY, Yang X, Chen D, Zuscik M, O'Keefe RJ. Axin1 and Axin2 are regulated by TGF- and mediate cross-talk between TGF- and Wnt signaling pathways. Annals of the New York Academy of Sciences. 1116: 82-99. PMID 18083923 DOI: 10.1196/Annals.1402.082  0.372
2007 Zuscik MJ, Ma L, Buckley T, Puzas JE, Drissi H, Schwarz EM, O'Keefe RJ. Lead induces chondrogenesis and alters transforming growth factor-beta and bone morphogenetic protein signaling in mesenchymal cell populations. Environmental Health Perspectives. 115: 1276-82. PMID 17805416 DOI: 10.1289/Ehp.10028  0.358
2007 Holz JD, Sheu TJ, Drissi H, Matsuzawa M, Zuscik MJ, Puzas JE. Environmental agents affect skeletal growth and development. Birth Defects Research. Part C, Embryo Today : Reviews. 81: 41-50. PMID 17539012 DOI: 10.1002/Bdrc.20087  0.312
2006 Li TF, Chen D, Wu Q, Chen M, Sheu TJ, Schwarz EM, Drissi H, Zuscik M, O'Keefe RJ. Transforming growth factor-beta stimulates cyclin D1 expression through activation of beta-catenin signaling in chondrocytes. The Journal of Biological Chemistry. 281: 21296-304. PMID 16690606 DOI: 10.1074/Jbc.M600514200  0.335
2006 Li TF, Darowish M, Zuscik MJ, Chen D, Schwarz EM, Rosier RN, Drissi H, O'Keefe RJ. Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 21: 4-16. PMID 16355269 DOI: 10.1359/Jbmr.050911  0.426
2006 Eliseev RA, Schwarz EM, Zuscik MJ, O'Keefe RJ, Drissi H, Rosier RN. Smad7 mediates inhibition of Saos2 osteosarcoma cell differentiation by NFkappaB. Experimental Cell Research. 312: 40-50. PMID 16259979 DOI: 10.1016/J.Yexcr.2005.09.016  0.401
2005 Dong Y, Drissi H, Chen M, Chen D, Zuscik MJ, Schwarz EM, O'Keefe RJ. Wnt-mediated regulation of chondrocyte maturation: modulation by TGF-beta. Journal of Cellular Biochemistry. 95: 1057-68. PMID 15962307 DOI: 10.1002/Jcb.20466  0.377
2005 Wei X, Zhang X, Zuscik MJ, Drissi MH, Schwarz EM, O'Keefe RJ. Fibroblasts express RANKL and support osteoclastogenesis in a COX-2-dependent manner after stimulation with titanium particles. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 20: 1136-48. PMID 15940366 DOI: 10.1359/Jbmr.050206  0.335
2005 Carmouche JJ, Puzas JE, Zhang X, Tiyapatanaputi P, Cory-Slechta DA, Gelein R, Zuscik M, Rosier RN, Boyce BF, O'Keefe RJ, Schwarz EM. Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency. Environmental Health Perspectives. 113: 749-55. PMID 15929899 DOI: 10.1289/Ehp.7596  0.336
2005 Drissi H, Zuscik M, Rosier R, O'Keefe R. Transcriptional regulation of chondrocyte maturation: potential involvement of transcription factors in OA pathogenesis. Molecular Aspects of Medicine. 26: 169-79. PMID 15811433 DOI: 10.1016/J.Mam.2005.01.003  0.394
2005 Clark CA, Schwarz EM, Zhang X, Ziran NM, Drissi H, O'Keefe RJ, Zuscik MJ. Differential regulation of EP receptor isoforms during chondrogenesis and chondrocyte maturation. Biochemical and Biophysical Research Communications. 328: 764-76. PMID 15694412 DOI: 10.1016/J.Bbrc.2004.11.074  0.355
2004 Li TF, Zuscik MJ, Ionescu AM, Zhang X, Rosier RN, Schwarz EM, Drissi H, O'Keefe RJ. PGE2 inhibits chondrocyte differentiation through PKA and PKC signaling. Experimental Cell Research. 300: 159-69. PMID 15383323 DOI: 10.1016/J.Yexcr.2004.06.019  0.371
2004 Li TF, Dong Y, Ionescu AM, Rosier RN, Zuscik MJ, Schwarz EM, O'Keefe RJ, Drissi H. Parathyroid hormone-related peptide (PTHrP) inhibits Runx2 expression through the PKA signaling pathway. Experimental Cell Research. 299: 128-36. PMID 15302580 DOI: 10.1016/J.Yexcr.2004.05.025  0.384
2004 Ferguson CM, Schwarz EM, Puzas JE, Zuscik MJ, Drissi H, O'Keefe RJ. Transforming growth factor-beta1 induced alteration of skeletal morphogenesis in vivo. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 22: 687-96. PMID 15183422 DOI: 10.1016/J.Orthres.2003.10.023  0.377
2004 Zhang X, Ziran N, Goater JJ, Schwarz EM, Puzas JE, Rosier RN, Zuscik M, Drissi H, O'Keefe RJ. Primary murine limb bud mesenchymal cells in long-term culture complete chondrocyte differentiation: TGF-beta delays hypertrophy and PGE2 inhibits terminal differentiation. Bone. 34: 809-17. PMID 15121012 DOI: 10.1016/J.Bone.2003.12.026  0.401
2004 Zuscik MJ, Baden JF, Wu Q, Sheu TJ, Schwarz EM, Drissi H, O'Keefe RJ, Puzas JE, Rosier RN. 5-azacytidine alters TGF-beta and BMP signaling and induces maturation in articular chondrocytes. Journal of Cellular Biochemistry. 92: 316-31. PMID 15108358 DOI: 10.1002/Jcb.20050  0.426
2004 Ionescu AM, Drissi H, Schwarz EM, Kato M, Puzas JE, McCance DJ, Rosier RN, Zuscik MJ, O'Keefe RJ. CREB Cooperates with BMP-stimulated Smad signaling to enhance transcription of the Smad6 promoter. Journal of Cellular Physiology. 198: 428-40. PMID 14755548 DOI: 10.1002/Jcp.10421  0.387
2003 Drissi MH, Li X, Sheu TJ, Zuscik MJ, Schwarz EM, Puzas JE, Rosier RN, O'Keefe RJ. Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes. Journal of Cellular Biochemistry. 90: 1287-98. PMID 14635200 DOI: 10.1002/Jcb.10677  0.393
2003 Zhang D, Schwarz EM, Rosier RN, Zuscik MJ, Puzas JE, O'Keefe RJ. ALK2 functions as a BMP type I receptor and induces Indian hedgehog in chondrocytes during skeletal development. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 18: 1593-604. PMID 12968668 DOI: 10.1359/Jbmr.2003.18.9.1593  0.401
2003 Li X, Ionescu AM, Schwarz EM, Zhang X, Drissi H, Puzas JE, Rosier RN, Zuscik MJ, O'Keefe RJ. Smad6 is induced by BMP-2 and modulates chondrocyte differentiation. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 21: 908-13. PMID 12919880 DOI: 10.1016/S0736-0266(03)00008-1  0.434
2003 Ionescu AM, Schwarz EM, Zuscik MJ, Drissi H, Puzas JE, Rosier RN, O'Keefe RJ. ATF-2 cooperates with Smad3 to mediate TGF-beta effects on chondrocyte maturation. Experimental Cell Research. 288: 198-207. PMID 12878171 DOI: 10.1016/S0014-4827(03)00181-2  0.375
2003 Zuscik MJ, Rosier RN, Schwarz EM. Altered negative regulation of transforming growth factor beta signaling in scleroderma: potential involvement of SMURF2 in disease. Arthritis and Rheumatism. 48: 1779-80. PMID 12847669 DOI: 10.1002/Art.11158  0.343
2003 Li X, Schwarz EM, Zuscik MJ, Rosier RN, Ionescu AM, Puzas JE, Drissi H, Sheu TJ, O'Keefe RJ. Retinoic acid stimulates chondrocyte differentiation and enhances bone morphogenetic protein effects through induction of Smad1 and Smad5. Endocrinology. 144: 2514-23. PMID 12746314 DOI: 10.1210/En.2002-220969  0.345
2003 Sheu TJ, Schwarz EM, Martinez DA, O'Keefe RJ, Rosier RN, Zuscik MJ, Puzas JE. A phage display technique identifies a novel regulator of cell differentiation. The Journal of Biological Chemistry. 278: 438-43. PMID 12403789 DOI: 10.1074/Jbc.M208292200  0.348
2002 Zuscik MJ, O'Keefe RJ, Gunter TE, Puzas JE, Schwarz EM, Rosier RN. Parathyroid hormone-related peptide regulation of chick tibial growth plate chondrocyte maturation requires protein kinase A. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 20: 1079-90. PMID 12382976 DOI: 10.1016/S0736-0266(02)00027-X  0.339
2002 Zuscik MJ, Pateder DB, Puzas JE, Schwarz EM, Rosier RN, O'Keefe RJ. Lead alters parathyroid hormone-related peptide and transforming growth factor-beta1 effects and AP-1 and NF-kappaB signaling in chondrocytes. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 20: 811-8. PMID 12168672 DOI: 10.1016/S0736-0266(02)00007-4  0.418
2000 Zuscik MJ, Sands S, Ross SA, Waugh DJ, Gaivin RJ, Morilak D, Perez DM. Overexpression of the alpha1B-adrenergic receptor causes apoptotic neurodegeneration: multiple system atrophy. Nature Medicine. 6: 1388-94. PMID 11100125 DOI: 10.1038/82207  0.314
1999 Zuscik MJ, Piascik MT, Perez DM. Cloning, cell-type specificity, and regulatory function of the mouse alpha(1B)-adrenergic receptor promoter. Molecular Pharmacology. 56: 1288-97. PMID 10570057 DOI: 10.1124/Mol.56.6.1288  0.314
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