Antonio Ferrer-Montiel - Publications

Institute of Molecular and Cellular Biology Universidad Miguel Hernández de Elche 

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Butrón D, Zamora-Carreras H, Devesa I, Treviño MA, Abian O, Velázquez-Campoy A, Bonache MÁ, Lagartera L, Martín-Martínez M, González-Rodríguez S, Baamonde A, Fernández-Carvajal A, Ferrer-Montiel A, Jiménez MÁ, González-Muñiz R. DD04107-Derived neuronal exocytosis inhibitor peptides: Evidences for synaptotagmin-1 as a putative target. Bioorganic Chemistry. 115: 105231. PMID 34388485 DOI: 10.1016/j.bioorg.2021.105231  1
2021 Journigan VB, Alarcón-Alarcón D, Feng Z, Wang Y, Liang T, Dawley DC, Amin ARMR, Montano C, Van Horn WD, Xie XQ, Ferrer-Montiel A, Fernández-Carvajal A. Structural and in Vitro Functional Characterization of a Menthyl TRPM8 Antagonist Indicates Species-Dependent Regulation. Acs Medicinal Chemistry Letters. 12: 758-767. PMID 34055223 DOI: 10.1021/acsmedchemlett.1c00001  1
2021 Bonache MÁ, Llabrés PJ, Martín-Escura C, De la Torre-Martínez R, Medina-Peris A, Butrón L, Gómez-Monterrey I, Roa AM, Fernández-Ballester G, Ferrer-Montiel A, Fernández-Carvajal A, González-Muñiz R. Phenylalanine-Derived β-Lactam TRPM8 Modulators. Configuration Effect on the Antagonist Activity. International Journal of Molecular Sciences. 22. PMID 33673444 DOI: 10.3390/ijms22052370  1
2021 Nikolaeva-Koleva M, Butron L, González-Rodríguez S, Devesa I, Valente P, Serafini M, Genazzani AA, Pirali T, Ballester GF, Fernández-Carvajal A, Ferrer-Montiel A. A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability. Scientific Reports. 11: 246. PMID 33420359 DOI: 10.1038/s41598-020-80725-z  1
2020 Dionisi M, Ruffinatti FA, Riva B, Lim D, Canta A, Meregalli C, Fumagalli G, Monza L, Ferrer-Montiel A, Fernandez-Carvajal A, Cavaletti G, Genazzani AA, Distasi C. Early Stimulation of TREK Channel Transcription and Activity Induced by Oxaliplatin-Dependent Cytosolic Acidification. International Journal of Molecular Sciences. 21. PMID 32998392 DOI: 10.3390/ijms21197164  0.08
2020 Fernández-Ballester G, Fernández-Carvajal A, Ferrer-Montiel A. Targeting thermoTRP ion channels: preclinical approaches and opportunities. Expert Opinion On Therapeutic Targets. 1-19. PMID 32972264 DOI: 10.1080/14728222.2020.1820987  1
2020 Fernández-Carvajal A, González-Muñiz R, Fernández-Ballester G, Ferrer-Montiel A. Investigational drugs in early phase clinical trials targeting thermotransient receptor potential (thermoTRP) channels. Expert Opinion On Investigational Drugs. PMID 32941080 DOI: 10.1080/13543784.2020.1825680  1
2020 Bonache MÁ, Martín-Escura C, de la Torre Martínez R, Medina A, González-Rodríguez S, Francesch A, Cuevas C, Roa AM, Fernández-Ballester G, Ferrer-Montiel A, Fernández-Carvajal A, González-Muñiz R. Highly functionalized β-lactams and 2-ketopiperazines as TRPM8 antagonists with antiallodynic activity. Scientific Reports. 10: 14154. PMID 32843690 DOI: 10.1038/S41598-020-70691-X  1
2020 Cabañero D, Ramírez-López A, Drews E, Schmöle A, Otte DM, Wawrzczak-Bargiela A, Huerga Encabo H, Kummer S, Ferrer-Montiel A, Przewlocki R, Zimmer A, Maldonado R. Protective role of neuronal and lymphoid cannabinoid CB receptors in neuropathic pain. Elife. 9. PMID 32687056 DOI: 10.7554/Elife.55582  0.01
2020 Cabañero D, Ramírez-López A, Drews E, Schmöle A, Otte DM, Wawrzczak-Bargiela A, Encabo HH, Kummer S, Ferrer-Montiel A, Przewlocki R, Zimmer A, Maldonado R. Author response: Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain Elife. DOI: 10.7554/Elife.55582.Sa2  0.01
2019 Journigan VB, Feng Z, Rahman S, Wang Y, Amin ARMR, Heffner CE, Bachtel N, Wang S, Gonzalez-Rodriguez S, Fernández-Carvajal A, Fernández-Ballester G, Hilton JK, Van Horn WD, Ferrer-Montiel A, Xie XQ, et al. Structure-based design of novel biphenyl amide antagonists of human Transient Receptor Potential Cation Channel Subfamily M Member 8 channels (TRPM8) with potential implications in the treatment of sensory neuropathies. Acs Chemical Neuroscience. PMID 31850745 DOI: 10.1021/Acschemneuro.9B00404  1
2019 Gonzalez Gil I, Zian D, Vázquez-Villa H, Hernandez-Torres G, Martinez RF, Khiar-Fernandez N, Rivera R, Kihara Y, Devesa I, Mathivanan S, Rosell Del Valle C, Zambrana-Infantes E, Puigdomenech M, Cincilla G, Sanchez-Martinez M, ... ... Ferrer-Montiel A, et al. A novel agonist of the type 1 lysophosphatidic acid receptor (LPA1), UCM-05194, shows efficacy in neuropathic pain amelioration. Journal of Medicinal Chemistry. PMID 31790581 DOI: 10.1021/Acs.Jmedchem.9B01287  1
2019 Pérez de Vega MJ, Fernández-Mendívil C, de la Torre-Martinez R, González-Rodríguez S, Mulet J, Sala F, Sala S, Criado M, Moreno-Fernandez S, Miguel M, Fernández-Carvajal A, Ferrer-Montiel A, López MG, González-Muñiz R. 1-(2',5'-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1-propanone (RGM079): A positive allosteric modulator of α7 nicotinic receptors with analgesic and neuroprotective activity. Acs Chemical Neuroscience. PMID 31322853 DOI: 10.1021/Acschemneuro.9B00364  1
2019 Solé L, Roig SR, Sastre D, Vallejo-Gracia A, Serrano-Albarrás A, Ferrer-Montiel A, Fernández-Ballester G, Tamkun MM, Felipe A. The calmodulin-binding tetraleucine motif of KCNE4 is responsible for association with Kv1.3. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201801164RR. PMID 30969795 DOI: 10.1096/Fj.201801164Rr  1
2019 Arribas-Blázquez M, Olivos-Oré LA, Barahona MV, Sánchez de la Muela M, Solar V, Jiménez E, Gualix J, McIntosh JM, Ferrer-Montiel A, Miras-Portugal MT, Artalejo AR. Overexpression of P2X3 and P2X7 Receptors and TRPV1 Channels in Adrenomedullary Chromaffin Cells in a Rat Model of Neuropathic Pain. International Journal of Molecular Sciences. 20. PMID 30609840 DOI: 10.3390/Ijms20010155  0.01
2018 Felipe A, Ferrer-Montiel A. The Spanish Ion Channel Initiative (SICI) Consortium: Ten Years (2008⁻2018) of a Network of Excellence on Ion Channel Research. International Journal of Molecular Sciences. 19. PMID 30413029 DOI: 10.3390/Ijms19113514  1
2018 Pérez de Vega MJ, Ferrer-Montiel A, González-Muñiz R. Recent progress in non-opioid analgesic peptides. Archives of Biochemistry and Biophysics. 660: 36-52. PMID 30342013 DOI: 10.1016/J.Abb.2018.10.011  1
2018 Artero-Morales M, González-Rodríguez S, Ferrer-Montiel A. TRP Channels as Potential Targets for Sex-Related Differences in Migraine Pain. Frontiers in Molecular Biosciences. 5: 73. PMID 30155469 DOI: 10.3389/Fmolb.2018.00073  0.01
2018 Bertamino A, Iraci N, Ostacolo C, Ambrosino P, Musella S, Di Sarno V, Ciaglia T, Pepe G, Sala M, Soldovieri MV, Mosca I, Gonzalez-Rodriguez S, Fernández-Carvajal A, Ferrer-Montiel A, Novellino E, et al. Identification of a Potent Tryptophan-based TRPM8 Antagonist With in vivo Analgesic Activity. Journal of Medicinal Chemistry. PMID 29939028 DOI: 10.1021/Acs.Jmedchem.8B00545  1
2018 Serafini M, Griglio A, Aprile S, Seiti F, Travelli C, Pattarino F, Grosa G, Sorba G, Genazzani AA, Gonzales-Rodriguez S, Butron L, Devesa I, Fernández-Carvajal A, Pirali T, Ferrer-Montiel A. Targeting transient receptor potential vanilloid 1 (TRPV1) channel softly: the discovery of Passerini adducts as a topical treatment for inflammatory skin disorders. Journal of Medicinal Chemistry. PMID 29722529 DOI: 10.1021/Acs.Jmedchem.8B00109  1
2018 Balsera B, Mulet J, Sala S, Sala F, de la Torre-Martínez R, González-Rodríguez S, Plata A, Naesens L, Fernández-Carvajal A, Ferrer-Montiel A, Criado M, Pérez de Vega MJ, González-Muñiz R. Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of α7 nicotinic receptors with analgesic activity. European Journal of Medicinal Chemistry. 143: 157-165. PMID 29174812 DOI: 10.1016/J.Ejmech.2017.10.083  1
2017 Quarta S, Camprubí-Robles M, Schweigreiter R, Matusica D, Haberberger RV, Proia RL, Bandtlow CE, Ferrer-Montiel A, Kress M. Sphingosine-1-Phosphate and the S1P3 Receptor Initiate Neuronal Retraction via RhoA/ROCK Associated with CRMP2 Phosphorylation. Frontiers in Molecular Neuroscience. 10: 317. PMID 29066950 DOI: 10.3389/Fnmol.2017.00317  1
2017 de la Torre-Martínez R, Bonache MA, Llabrés-Campaner PJ, Balsera B, Fernández-Carvajal A, Fernández-Ballester G, Ferrer-Montiel A, Pérez de Vega MJ, González-Muñiz R. Synthesis, high-throughput screening and pharmacological characterization of β-lactam derivatives as TRPM8 antagonists. Scientific Reports. 7: 10766. PMID 28883526 DOI: 10.1038/S41598-017-10913-X  1
2017 Ciardo MG, Ferrer-Montiel A. Lipids as central modulators of sensory TRP channels. Biochimica Et Biophysica Acta. PMID 28432033 DOI: 10.1016/J.Bbamem.2017.04.012  1
2016 Vázquez-Jiménez L, Garrido M, Miceli M, Prats E, Ferrer-Montiel A, Teixidó M, Jimeno C, Messeguer A. Synthesis and in vitro, ex-vivo and in vivo activity of hybrid compounds linking a potent ROS and RNS scavenger activity with diverse substrates addressed to pass across the blood-brain barrier. European Journal of Medicinal Chemistry. 123: 788-802. PMID 27541262 DOI: 10.1016/J.Ejmech.2016.08.007  1
2016 Mathivanan S, Devesa I, Changeux JP, Ferrer-Montiel A. Bradykinin Induces TRPV1 Exocytotic Recruitment in Peptidergic Nociceptors. Frontiers in Pharmacology. 7: 178. PMID 27445816 DOI: 10.3389/Fphar.2016.00178  1
2016 Pérez de Vega MJ, Gómez-Monterrey I, Ferrer-Montiel A, González-Muñiz R. Transient Receptor Potential Melastatin 8 Channel (TRPM8) Modulation: Cool Entryway for Treating Pain and Cancer. Journal of Medicinal Chemistry. 59: 10006-10029. PMID 27437828 DOI: 10.1021/Acs.Jmedchem.6B00305  1
2016 Criado M, Balsera B, Mulet J, Sala S, Sala F, la Torre-Martínez R, Fernández-Carvajal A, Ferrer-Montiel A, Moreno-Fernández S, Miguel M, Pérez de Vega MJ, González-Muñiz R. 1,3-diphenylpropan-1-ones as allosteric modulators of α7 nACh receptors with analgesic and antioxidant properties. Future Medicinal Chemistry. PMID 27161515 DOI: 10.4155/Fmc-2015-0001  1
2016 Taberner FJ, Devesa I, Ferrer-Montiel A. Calcium Entry Through Thermosensory Channels. Advances in Experimental Medicine and Biology. 898: 265-304. PMID 27161233 DOI: 10.1007/978-3-319-26974-0_12  1
2016 Guiretti D, Sempere A, Lopez-Atalaya JP, Ferrer-Montiel A, Barco A, Valor LM. Specific promoter deacetylation of histone H3 is conserved across mouse models of Huntington's disease in the absence of bulk changes. Neurobiology of Disease. 89: 190-201. PMID 26851501 DOI: 10.1016/J.Nbd.2016.02.004  1
2016 Bertamino A, Ostacolo C, Ambrosino P, Musella S, Di Sarno V, Ciaglia T, Soldovieri MV, Iraci N, Fernandez Carvajal A, de la Torre-Martinez R, Ferrer-Montiel A, Gonzalez Muniz R, Novellino E, Taglialatela M, Campiglia P, et al. Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators. Journal of Medicinal Chemistry. 59: 2179-91. PMID 26847872 DOI: 10.1021/Acs.Jmedchem.5B01914  1
2015 de la Peña E, Gomis A, Ferrer-Montiel A, Belmonte C. TRPV1 channel modulation by hyaluronan reduces pain. Channels (Austin, Tex.). 0. PMID 26517313 DOI: 10.1080/19336950.2015.1109300  1
2015 Ciardo MG, Andrés-Bordería A, Cuesta N, Valente P, Camprubí-Robles M, Yang J, Planells-Cases R, Ferrer-Montiel A. Whirlin increases TRPV1 channel expression and cellular stability. Biochimica Et Biophysica Acta. PMID 26516054 DOI: 10.1016/J.Bbamcr.2015.10.016  1
2015 Caires R, Luis E, Taberner FJ, Fernandez-Ballester G, Ferrer-Montiel A, Balazs EA, Gomis A, Belmonte C, de la Peña E. Hyaluronan modulates TRPV1 channel opening, reducing peripheral nociceptor activity and pain. Nature Communications. 6: 8095. PMID 26311398 DOI: 10.1038/Ncomms9095  1
2015 Gregorio-Teruel L, Valente P, Liu B, Fernández-Ballester G, Qin F, Ferrer-Montiel A. The Integrity of the TRP Domain Is Pivotal for Correct TRPV1 Channel Gating. Biophysical Journal. 109: 529-41. PMID 26244735 DOI: 10.1016/J.Bpj.2015.06.039  1
2015 Taberner FJ, Fernández-Ballester G, Fernández-Carvajal A, Ferrer-Montiel A. TRP channels interaction with lipids and its implications in disease. Biochimica Et Biophysica Acta. 1848: 1818-27. PMID 25838124 DOI: 10.1016/J.Bbamem.2015.03.022  1
2014 Devesa I, Ferrándiz-Huertas C, Mathivanan S, Wolf C, Luján R, Changeux JP, Ferrer-Montiel A. αCGRP is essential for algesic exocytotic mobilization of TRPV1 channels in peptidergic nociceptors. Proceedings of the National Academy of Sciences of the United States of America. 111: 18345-50. PMID 25489075 DOI: 10.1073/Pnas.1420252111  1
2014 Fresno N, Pérez-Fernández R, Goicoechea C, Alkorta I, Fernández-Carvajal A, de la Torre-Martínez R, Quirce S, Ferrer-Montiel A, Martín MI, Goya P, Elguero J. Adamantyl analogues of paracetamol as potent analgesic drugs via inhibition of TRPA1. Plos One. 9: e113841. PMID 25438056 DOI: 10.1371/Journal.Pone.0113841  0.01
2014 Ferrandiz-Huertas C, Mathivanan S, Wolf CJ, Devesa I, Ferrer-Montiel A. Trafficking of ThermoTRP Channels. Membranes. 4: 525-64. PMID 25257900 DOI: 10.3390/membranes4030525  1
2014 Balsera B, Mulet J, Fernández-Carvajal A, de la Torre-Martínez R, Ferrer-Montiel A, Hernández-Jiménez JG, Estévez-Herrera J, Borges R, Freitas AE, López MG, García-López MT, González-Muñiz R, Pérez de Vega MJ, Valor LM, Svobodová L, et al. Chalcones as positive allosteric modulators of α7 nicotinic acetylcholine receptors: a new target for a privileged structure. European Journal of Medicinal Chemistry. 86: 724-39. PMID 25232969 DOI: 10.1016/J.Ejmech.2014.09.039  1
2014 Taberner FJ, López-Córdoba A, Fernández-Ballester G, Korchev Y, Ferrer-Montiel A. The region adjacent to the C-end of the inner gate in transient receptor potential melastatin 8 (TRPM8) channels plays a central role in allosteric channel activation. The Journal of Biological Chemistry. 289: 28579-94. PMID 25157108 DOI: 10.1074/Jbc.M114.577478  1
2014 Bonache MÁ, Balsera B, López-Méndez B, Millet O, Brancaccio D, Gómez-Monterrey I, Carotenuto A, Pavone LM, Reille-Seroussi M, Gagey-Eilstein N, Vidal M, de la Torre-Martinez R, Fernández-Carvajal A, Ferrer-Montiel A, García-López MT, et al. De novo designed library of linear helical peptides: an exploratory tool in the discovery of protein-protein interaction modulators. Acs Combinatorial Science. 16: 250-8. PMID 24725184 DOI: 10.1021/Co500005X  1
2014 Gregorio-Teruel L, Valente P, González-Ros JM, Fernández-Ballester G, Ferrer-Montiel A. Mutation of I696 and W697 in the TRP box of vanilloid receptor subtype I modulates allosteric channel activation. The Journal of General Physiology. 143: 361-75. PMID 24567510 DOI: 10.1085/Jgp.201311070  1
2014 Devesa I, Ferrer-Montiel A. Neurotrophins, endocannabinoids and thermo-transient receptor potential: a threesome in pain signalling. The European Journal of Neuroscience. 39: 353-62. PMID 24494676 DOI: 10.1111/Ejn.12455  1
2013 Martínez-Mármol R, Pérez-Verdaguer M, Roig SR, Vallejo-Gracia A, Gotsi P, Serrano-Albarrás A, Bahamonde MI, Ferrer-Montiel A, Fernández-Ballester G, Comes N, Felipe A. A non-canonical di-acidic signal at the C-terminus of Kv1.3 determines anterograde trafficking and surface expression. Journal of Cell Science. 126: 5681-91. PMID 24144698 DOI: 10.1242/Jcs.134825  1
2013 Bavassano C, Marvaldi L, Langeslag M, Sarg B, Lindner H, Klimaschewski L, Kress M, Ferrer-Montiel A, Knaus HG. Identification of voltage-gated K(+) channel beta 2 (Kvβ2) subunit as a novel interaction partner of the pain transducer Transient Receptor Potential Vanilloid 1 channel (TRPV1). Biochimica Et Biophysica Acta. 1833: 3166-75. PMID 24036102 DOI: 10.1016/J.Bbamcr.2013.09.001  1
2013 Babakinejad B, Jönsson P, López Córdoba A, Actis P, Novak P, Takahashi Y, Shevchuk A, Anand U, Anand P, Drews A, Ferrer-Montiel A, Klenerman D, Korchev YE. Local delivery of molecules from a nanopipette for quantitative receptor mapping on live cells. Analytical Chemistry. 85: 9333-42. PMID 24004146 DOI: 10.1021/Ac4021769  1
2013 Devesa I, Fernández-Ballester G, Ferrer-Montiel A. Targeting protein-protein interactions to rescue Δf508-cftr: a novel corrector approach to treat cystic fibrosis. Embo Molecular Medicine. 5: 1462-4. PMID 23983009 DOI: 10.1002/emmm.201303301  1
2013 Belghiti M, Estévez-Herrera J, Giménez-Garzó C, González-Usano A, Montoliu C, Ferrer-Montiel A, Felipo V, Planells-Cases R. Potentiation of the transient receptor potential vanilloid 1 channel contributes to pruritogenesis in a rat model of liver disease. The Journal of Biological Chemistry. 288: 9675-85. PMID 23408423 DOI: 10.1074/Jbc.M113.455162  1
2013 Pérez-Faginas P, Aranda MT, García-López MT, Infantes L, Fernández-Carvajal A, González-Ros JM, Ferrer-Montiel A, González-Muñiz R. Highly functionalized 1,2-diamino compounds through reductive amination of amino acid-derived β-keto esters. Plos One. 8: e53231. PMID 23308167 DOI: 10.1371/Journal.Pone.0053231  1
2013 Giudici AM, Molina ML, Ayala JL, Montoya E, Renart ML, Fernández AM, Encinar JA, Ferrer-Montiel AV, Poveda JA, González-Ros JM. Detergent-labile, supramolecular assemblies of KcsA: relative abundance and interactions involved. Biochimica Et Biophysica Acta. 1828: 193-200. PMID 23022492 DOI: 10.1016/j.bbamem.2012.09.020  1
2013 Taberner FJ, López-Córdoba A, Fernández-Ballester G, Korchev Y, Ferrer-Montiel A. Mutations in the TRP Domain Differentially affect the Function of TRPM8 Biophysical Journal. 104: 4-6. DOI: 10.1016/J.Bpj.2012.11.2521  1
2012 Ferrer-Montiel A, Fernández-Carvajal A, Planells-Cases R, Fernández-Ballester G, González-Ros JM, Messeguer A, González-Muñiz R. Advances in modulating thermosensory TRP channels. Expert Opinion On Therapeutic Patents. 22: 999-1017. PMID 22835143 DOI: 10.1517/13543776.2012.711320  1
2012 Sanz-Salvador L, Andrés-Borderia A, Ferrer-Montiel A, Planells-Cases R. Agonist- and Ca2+-dependent desensitization of TRPV1 channel targets the receptor to lysosomes for degradation. The Journal of Biological Chemistry. 287: 19462-71. PMID 22493457 DOI: 10.1074/Jbc.M111.289751  1
2012 Navarro A, Encinar JA, López-Méndez B, Aguado-Llera D, Prieto J, Gómez J, Martínez-Cruz LA, Millet O, González-Ros JM, Fernández-Ballester G, Neira JL, Ferrer-Montiel A. Mutation of Ser-50 and Cys-66 in Snapin modulates protein structure and stability. Biochemistry. 51: 3470-84. PMID 22471585 DOI: 10.1021/Bi201574T  1
2012 Ponsati B, Carreño C, Curto-Reyes V, Valenzuela B, Duart MJ, Van den Nest W, Cauli O, Beltran B, Fernandez J, Borsini F, Caprioli A, Di Serio S, Veretchy M, Baamonde A, Menendez L, ... ... Ferrer-Montiel A, et al. An inhibitor of neuronal exocytosis (DD04107) displays long-lasting in vivo activity against chronic inflammatory and neuropathic pain. The Journal of Pharmacology and Experimental Therapeutics. 341: 634-45. PMID 22393248 DOI: 10.1124/Jpet.111.190678  1
2011 Fernández-Ballester G, Fernández-Carvajal A, González-Ros JM, Ferrer-Montiel A. Ionic channels as targets for drug design: a review on computational methods. Pharmaceutics. 3: 932-53. PMID 24309315 DOI: 10.3390/Pharmaceutics3040932  1
2011 Fernández-Carvajal A, Fernández-Ballester G, Devesa I, González-Ros JM, Ferrer-Montiel A. New strategies to develop novel pain therapies: addressing thermoreceptors from different points of view. Pharmaceuticals (Basel, Switzerland). 5: 16-48. PMID 24288041 DOI: 10.3390/Ph5010016  1
2011 Devesa I, Planells-Cases R, Fernández-Ballester G, González-Ros JM, Ferrer-Montiel A, Fernández-Carvajal A. Role of the transient receptor potential vanilloid 1 in inflammation and sepsis. Journal of Inflammation Research. 4: 67-81. PMID 22096371 DOI: 10.2147/Jir.S12978  1
2011 Vidal-Mosquera M, Fernández-Carvajal A, Moure A, Valente P, Planells-Cases R, González-Ros JM, Bujons J, Ferrer-Montiel A, Messeguer A. Triazine-based vanilloid 1 receptor open channel blockers: design, synthesis, evaluation, and SAR analysis. Journal of Medicinal Chemistry. 54: 7441-52. PMID 21950613 DOI: 10.1021/Jm200981S  1
2011 Gerona-Navarro G, González-Muñiz R, Fernández-Carvajal A, González-Ros JM, Ferrer-Montiel A, Carreño C, Albericio F, Royo M. Solid-phase synthesis of a library of amphipatic hydantoins. Discovery of new hits for TRPV1 blockade. Acs Combinatorial Science. 13: 458-65. PMID 21671576 DOI: 10.1021/Co1000986  1
2011 Zaccaro L, García-López MT, González-Muñiz R, García-Martínez C, Ferrer-Montiel A, Albericio F, Royo M. TRPV1 modulators: structure-activity relationships using a rational combinatorial approach. Bioorganic & Medicinal Chemistry Letters. 21: 3541-5. PMID 21612926 DOI: 10.1016/J.Bmcl.2011.04.141  1
2011 Goswami C, Kuhn J, Dina OA, Fernández-Ballester G, Levine JD, Ferrer-Montiel A, Hucho T. Estrogen destabilizes microtubules through an ion-conductivity-independent TRPV1 pathway. Journal of Neurochemistry. 117: 995-1008. PMID 21480900 DOI: 10.1111/J.1471-4159.2011.07270.X  1
2011 Valente P, Fernández-Carvajal A, Camprubí-Robles M, Gomis A, Quirce S, Viana F, Fernández-Ballester G, González-Ros JM, Belmonte C, Planells-Cases R, Ferrer-Montiel A. Membrane-tethered peptides patterned after the TRP domain (TRPducins) selectively inhibit TRPV1 channel activity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1628-40. PMID 21307333 DOI: 10.1096/Fj.10-174433  1
2011 Planells-Cases R, Valente P, Ferrer-Montiel A, Qin F, Szallasi A. Complex regulation of TRPV1 and related thermo-TRPs: implications for therapeutic intervention. Advances in Experimental Medicine and Biology. 704: 491-515. PMID 21290313 DOI: 10.1007/978-94-007-0265-3_27  1
2011 Ferrándiz-Huertas C, Fernández-Carvajal A, Ferrer-Montiel A. Rab4 interacts with the human P-glycoprotein and modulates its surface expression in multidrug resistant K562 cells. International Journal of Cancer. 128: 192-205. PMID 20209493 DOI: 10.1002/Ijc.25310  1
2010 Pérez de Vega MJ, García-López MT, Zaccaro L, Royo M, Albericio F, Fernández-Carvajal A, Ferrer-Montiel A, González-Muñiz R. Solid-phase synthesis of new Trp(Nps)-containing dipeptide derivatives as TRPV1 channel blockers. Molecules (Basel, Switzerland). 15: 4924-33. PMID 20657400 DOI: 10.3390/Molecules15074924  1
2010 Lainez S, Valente P, Ontoria-Oviedo I, Estevez-Herrera J, Camprubi-Robles M, Ferrer-Montiel A, Planells-Cases R. GABAA receptor associated protein (GABARAP) modulates TRPV1 expression and channel function and desensitization The Faseb Journal. 24: 1958-1970. PMID 20179142 DOI: 10.1096/Fj.09-151472  1
2010 Camprubí-Robles M, Ferrer-Montiel A, Planells-Cases R. Contribution of Ion Channel Trafficking to Nociceptor Sensitization The Open Pain Journal. 3: 108-116. DOI: 10.2174/1876386301003010108  1
2010 Ferrer-Montiel A. EDITORIAL-Mechanisms of Nociceptor Sensitization The Open Pain Journal. 3: 66-66. DOI: 10.2174/1876386301003010066  0.01
2009 Viana F, Ferrer-Montiel A. TRPA1 modulators in preclinical development. Expert Opinion On Therapeutic Patents. 19: 1787-99. PMID 19939193 DOI: 10.1517/13543770903393771  1
2009 Malkia A, Pertusa M, Fernández-Ballester G, Ferrer-Montiel A, Viana F. Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels. Molecular Pain. 5: 62. PMID 19886999 DOI: 10.1186/1744-8069-5-62  1
2009 Camprubí-Robles M, Planells-Cases R, Ferrer-Montiel A. Differential contribution of SNARE-dependent exocytosis to inflammatory potentiation of TRPV1 in nociceptors The Faseb Journal. 23: 3722-3733. PMID 19584302 DOI: 10.1096/Fj.09-134346  1
2009 Ferrer-Montiel A, Camprubí-Robles M, García-Sanz N, Sempere A, Valente P, Nest WVD, Carreño C. The contribution of neurogenic inflammation to sensitive skin: concepts, mechanisms and cosmeceutical intervention International Journal of Cosmetic Science. 31: 477-477. DOI: 10.1111/J.1468-2494.2009.00530_1.X  1
2008 Messeguer J, Cortés N, García-Sanz N, Navarro-Vendrell G, Ferrer-Montiel A, Messeguer A. Synthesis of a positional scanning library of pentamers of N-alkylglycines assisted by microwave activation and validation via the identification of trypsin inhibitors. Journal of Combinatorial Chemistry. 10: 974-80. PMID 18847288 DOI: 10.1021/Cc800144X  1
2008 Fernández-Ballester G, Ferrer-Montiel A. Molecular Modeling of the Full-length Human TRPV1 Channel in Closed and Desensitized States The Journal of Membrane Biology. 223: 161-172. PMID 18791833 DOI: 10.1007/S00232-008-9123-7  1
2008 Valera E, Sánchez-Martín FJ, Ferrer-Montiel AV, Messeguer A, Merino JM. NMDA-induced neuroprotection in hippocampal neurons is mediated through the protein kinase A and CREB (cAMP-response element-binding protein) pathway. Neurochemistry International. 53: 148-54. PMID 18694792 DOI: 10.1016/j.neuint.2008.07.007  1
2008 Kress M, Karasek J, Ferrer-Montiel AV, Scherbakov N, Haberberger RV. TRPC channels and diacylglycerol dependent calcium signaling in rat sensory neurons. Histochemistry and Cell Biology. 130: 655-67. PMID 18663462 DOI: 10.1007/S00418-008-0477-9  1
2008 Valente P, García-Sanz N, Gomis A, Fernández-Carvajal A, Fernández-Ballester G, Viana F, Belmonte C, Ferrer-Montiel A. Identification of molecular determinants of channel gating in the transient receptor potential box of vanilloid receptor I. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3298-309. PMID 18559878 DOI: 10.1096/Fj.08-107425  1
2007 Planells-Cases1 R, Ferrer-Montiel A. Drug design and development through the vanilloid receptor. Expert Opinion On Drug Discovery. 2: 1053-63. PMID 23484872 DOI: 10.1517/17460441.2.8.1053  0.01
2007 Quintanar-Audelo M, Fernández-Carvajal A, Van Den Nest W, Carreño C, Ferrer-Montiel A, Albericio F. Design and synthesis of indole-based peptoids as potent noncompetitive antagonists of transient receptor potential vanilloid 1. Journal of Medicinal Chemistry. 50: 6133-43. PMID 17985859 DOI: 10.1021/Jm070612V  1
2007 García-Sanz N, Valente P, Gomis A, Fernández-Carvajal A, Fernández-Ballester G, Viana F, Belmonte C, Ferrer-Montiel A. A role of the transient receptor potential domain of vanilloid receptor I in channel gating. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11641-50. PMID 17959807 DOI: 10.1523/Jneurosci.2457-07.2007  1
2006 Messeguer A, Planells-Cases R, Ferrer-Montiel A. Physiology and pharmacology of the vanilloid receptor. Current Neuropharmacology. 4: 1-15. PMID 18615132 DOI: 10.2174/157015906775202995  1
2006 Planells-Cases R, Lerma J, Ferrer-Montiel A. Pharmacological intervention at ionotropic glutamate receptor complexes. Current Pharmaceutical Design. 12: 3583-96. PMID 17073661 DOI: 10.2174/138161206778522092  1
2006 García-Martínez C, Fernández-Carvajal A, Valenzuela B, Gomis A, Van Den Nest W, Ferroni S, Carreño C, Belmonte C, Ferrer-Montiel A. Design and characterization of a noncompetitive antagonist of the transient receptor potential vanilloid subunit 1 channel with in vivo analgesic and anti-inflammatory activity. The Journal of Pain : Official Journal of the American Pain Society. 7: 735-46. PMID 17018334 DOI: 10.1016/J.Jpain.2006.03.008  1
2006 Bonache MA, García-Martínez C, García de Diego L, Carreño C, Pérez de Vega MJ, García-López MT, Ferrer-Montiel A, González-Muñiz R. Old molecules for new receptors: Trp(Nps) dipeptide derivatives as vanilloid TRPV1 channel blockers. Chemmedchem. 1: 429-38. PMID 16892378 DOI: 10.1002/cmdc.200500094  1
2006 Carteron C, Ferrer-Montiel A, Cabedo H. Characterization of a neural-specific splicing form of the human neuregulin 3 gene involved in oligodendrocyte survival. Journal of Cell Science. 119: 898-909. PMID 16478787 DOI: 10.1242/Jcs.02799  1
2006 Malet G, Martín AG, Orzáez M, Vicent MJ, Masip I, Sanclimens G, Ferrer-Montiel A, Mingarro I, Messeguer A, Fearnhead HO, Pérez-Payá E. Small molecule inhibitors of Apaf-1-related caspase- 3/-9 activation that control mitochondrial-dependent apoptosis. Cell Death and Differentiation. 13: 1523-32. PMID 16341125 DOI: 10.1038/Sj.Cdd.4401828  1
2005 Planells-Cases R, Garcìa-Sanz N, Morenilla-Palao C, Ferrer-Montiel A. Functional aspects and mechanisms of TRPV1 involvement in neurogenic inflammation that leads to thermal hyperalgesia. Pflugers Archiv : European Journal of Physiology. 451: 151-9. PMID 15909179 DOI: 10.1007/S00424-005-1423-5  1
2005 Caprini M, Fava M, Valente P, Fernandez-Ballester G, Rapisarda C, Ferroni S, Ferrer-Montiel A. Molecular compatibility of the channel gate and the N terminus of S5 segment for voltage-gated channel activity. The Journal of Biological Chemistry. 280: 18253-64. PMID 15749711 DOI: 10.1074/Jbc.M413389200  1
2005 Masip I, Cortés N, Abad MJ, Guardiola M, Pérez-Payá E, Ferragut J, Ferrer-Montiel A, Messeguer A. Design and synthesis of an optimized positional scanning library of peptoids: identification of novel multidrug resistance reversal agents. Bioorganic & Medicinal Chemistry. 13: 1923-9. PMID 15727848 DOI: 10.1016/J.Bmc.2005.01.024  1
2005 Martín-Orozco E, Ferragut JA, Garcia-Peñarrubia P, Ferrer-Montiel A. Acquisition of multidrug resistance by L1210 leukemia cells decreases their tumorigenicity and enhances their susceptibility to the host immune response. Cancer Immunology, Immunotherapy : Cii. 54: 328-36. PMID 15692844 DOI: 10.1007/S00262-004-0588-7  0.01
2005 Abad-Merin MJ, Cortés N, Masip I, Pérez-Payá E, Ferragut JA, Messeguer A, Ferrer-Montiel A. Trimers of N-alkylglycines are potent modulators of the multidrug resistance phenotype. The Journal of Pharmacology and Experimental Therapeutics. 313: 112-20. PMID 15644429 DOI: 10.1124/Jpet.104.078014  1
2004 Ibañez C, Blanes-Mira C, Fernández-Ballester G, Planells-Cases R, Ferrer-Montiel A. Modulation of botulinum neurotoxin A catalytic domain stability by tyrosine phosphorylation. Febs Letters. 578: 121-7. PMID 15581628 DOI: 10.1016/J.Febslet.2004.10.084  1
2004 Pastor MT, Mora P, Ferrer-Montiel A, Pérez-Payá E. Design of bioactive and structurally well-defined peptides from conformationally restricted libraries. Biopolymers. 76: 357-65. PMID 15386263 DOI: 10.1002/Bip.20142  1
2004 García-Sanz N, Fernández-Carvajal A, Morenilla-Palao C, Planells-Cases R, Fajardo-Sánchez E, Fernández-Ballester G, Ferrer-Montiel A. Identification of a tetramerization domain in the C terminus of the vanilloid receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5307-14. PMID 15190102 DOI: 10.1523/Jneurosci.0202-04.2004  1
2004 Cabedo H, Carteron C, Ferrer-Montiel A. Oligomerization of the sensory and motor neuron-derived factor prevents protein O-glycosylation. The Journal of Biological Chemistry. 279: 33623-9. PMID 15159404 DOI: 10.1074/Jbc.M401962200  1
2004 Ferrer-Montiel A, García-Martínez C, Morenilla-Palao C, García-Sanz N, Fernández-Carvajal A, Fernández-Ballester G, Planells-Cases R. Molecular architecture of the vanilloid receptor. Insights for drug design. European Journal of Biochemistry. 271: 1820-6. PMID 15128292 DOI: 10.1111/j.1432-1033.2004.04083.x  1
2004 Morenilla-Palao C, Planells-Cases R, García-Sanz N, Ferrer-Montiel A. Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity. The Journal of Biological Chemistry. 279: 25665-72. PMID 15066994 DOI: 10.1074/Jbc.M311515200  1
2004 Masip I, Ferrándiz-Huertas C, García-Martínez C, Ferragut JA, Ferrer-Montiel A, Messeguer A. Synthesis of a library of 3-oxopiperazinium and perhydro-3-oxo-1,4-diazepinium derivatives and identification of bioactive compounds. Journal of Combinatorial Chemistry. 6: 135-41. PMID 14714997 DOI: 10.1021/Cc030002Q  1
2004 Blanes-Mira C, Merino JM, Valera E, Fernández-Ballester G, Gutiérrez LM, Viniegra S, Pérez-Payá E, Ferrer-Montiel A. Small peptides patterned after the N-terminus domain of SNAP25 inhibit SNARE complex assembly and regulated exocytosis. Journal of Neurochemistry. 88: 124-35. PMID 14675156 DOI: 10.1046/J.1471-4159.2003.02133.X  1
2003 Planells-Cases R, Pérez-Payá E, Messeguer A, Carreño C, Ferrer-Montiel A. Small molecules targeting the NMDA receptor complex as drugs for neuropathic pain. Mini Reviews in Medicinal Chemistry. 3: 749-56. PMID 14529515 DOI: 10.2174/1389557033487782  1
2003 Blanes-Mira C, Pastor MT, Valera E, Fernández-Ballester G, Merino JM, Gutierrez LM, Perez-Payá E, Ferrer-Montiel A. Identification of SNARE complex modulators that inhibit exocytosis from an alpha-helix-constrained combinatorial library. The Biochemical Journal. 375: 159-66. PMID 12852787 DOI: 10.1042/Bj20030509  1
2003 Caprini M, Gomis A, Cabedo H, Planells-Cases R, Belmonte C, Viana F, Ferrer-Montiel A. GAP43 stimulates inositol trisphosphate-mediated calcium release in response to hypotonicity. The Embo Journal. 22: 3004-14. PMID 12805215 DOI: 10.1093/Emboj/Cdg294  1
2002 Valera E, Fernández-Salguero PM, Planells-Cases R, Messeguer A, Van Den Nest W, Carreño C, Ferrer-Montiel A, Merino JM. Neuroprotection against excitotoxicity by N-alkylglycines in rat hippocampal neurons. Neuromolecular Medicine. 2: 271-80. PMID 12622405 DOI: 10.1385/Nmm:2:3:271  1
2002 Planells-Cases R, Montoliu C, Humet M, Fernández AM, García-Martínez C, Valera E, Merino JM, Pérez-Payá E, Messeguer A, Felipo V, Ferrer-Montiel A. A novel N-methyl-D-aspartate receptor open channel blocker with in vivo neuroprotectant activity. The Journal of Pharmacology and Experimental Therapeutics. 302: 163-73. PMID 12065713 DOI: 10.1124/Jpet.302.1.163  1
2002 Montoliu C, Humet M, Canales JJ, Burda J, Planells-Cases R, Sánchez-Baeza F, Carbonell T, Pérez-Payá E, Messeguer A, Ferrer-Montiel A, Felipo V. Prevention of in vivo excitotoxicity by a family of trialkylglycines, a novel class of neuroprotectants. The Journal of Pharmacology and Experimental Therapeutics. 301: 29-36. PMID 11907154 DOI: 10.1124/Jpet.301.1.29  1
2002 Cabedo H, Luna C, Fernandez AM, Gallar J, Ferrer-Montiel A. Molecular determinants of the sensory and motor neuron-derived factor insertion into plasma membrane. The Journal of Biological Chemistry. 277: 19905-12. PMID 11896060 DOI: 10.1074/Jbc.M201587200  1
2002 García-Martinez C, Humet M, Planells-Cases R, Gomis A, Caprini M, Viana F, De La Pena E, Sanchez-Baeza F, Carbonell T, De Felipe C, Pérez-Paya E, Belmonte C, Messeguer A, Ferrer-Montiel A. Attenuation of thermal nociception and hyperalgesia by VR1 blockers. Proceedings of the National Academy of Sciences of the United States of America. 99: 2374-9. PMID 11854530 DOI: 10.1073/Pnas.022285899  1
2001 Blanes-Mira C, Ibañez C, Fernández-Ballester G, Planells-Cases R, Pérez-Payá E, Ferrer-Montiel A. Thermal stabilization of the catalytic domain of botulinum neurotoxin E by phosphorylation of a single tyrosine residue. Biochemistry. 40: 2234-42. PMID 11329292 DOI: 10.1021/Bi001919Y  1
2001 Caprini M, Ferroni S, Planells-Cases R, Rueda J, Rapisarda C, Ferrer-Montiel A, Montal M. Structural compatibility between the putative voltage sensor of voltage-gated K+ channels and the prokaryotic KcsA channel. The Journal of Biological Chemistry. 276: 21070-6. PMID 11274182 DOI: 10.1074/Jbc.M100487200  1
1998 Encinar JA, Fernández A, Ferragut JA, González-Ros JM, DasGupta BR, Montal M, Ferrer-Montiel A. Structural stabilization of botulinum neurotoxins by tyrosine phosphorylation. Febs Letters. 429: 78-82. PMID 9657387 DOI: 10.1016/S0014-5793(98)00571-7  1
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