| Year |
Citation |
Score |
| 2023 |
Martín-Escura C, Bonache MÁ, Medina JA, Medina-Peris A, De Andrés-López J, González-Rodríguez S, Kerselaers S, Fernández-Ballester G, Voets T, Ferrer-Montiel A, Fernández-Carvajal A, González-Muñiz R. β-Lactam TRPM8 Antagonists Derived from Phe-Phenylalaninol Conjugates: Structure-Activity Relationships and Antiallodynic Activity. International Journal of Molecular Sciences. 24. PMID 37834342 DOI: 10.3390/ijms241914894 |
0.743 |
|
| 2023 |
Giorgi S, Lamberti A, Butrón L, Gross-Amat O, Alarcón-Alarcón D, Rodríguez-Cañas E, Fernández-Carvajal A, Ferrer-Montiel A. Compartmentalized primary cultures of dorsal root ganglion neurons to model peripheral pathophysiological conditions. Molecular Pain. 19: 17448069231197102. PMID 37578145 DOI: 10.1177/17448069231197102 |
0.644 |
|
| 2023 |
Butron L, Nikolaeva-Koleva M, Sempere A, Rivero V, Fernandez-Ballester G, Espinosa A, Vergassola M, Mastrocola E, Zucchi S, Ragni L, Fernández-Carvajal A, Mangano G, Ferrer-Montiel A, Devesa I. Design and validation of neuronal exocytosis blocking peptides as potential novel antiperspirants. Experimental Dermatology. PMID 37009806 DOI: 10.1111/exd.14804 |
0.653 |
|
| 2023 |
Fernández-Ballester G, Fernández-Carvajal A, Ferrer-Montiel A. Progress in the Structural Basis of thermoTRP Channel Polymodal Gating. International Journal of Molecular Sciences. 24. PMID 36614186 DOI: 10.3390/ijms24010743 |
0.756 |
|
| 2022 |
Blanes-Mira C, Fernández-Aguado P, de Andrés-López J, Fernández-Carvajal A, Ferrer-Montiel A, Fernández-Ballester G. Comprehensive Survey of Consensus Docking for High-Throughput Virtual Screening. Molecules (Basel, Switzerland). 28. PMID 36615367 DOI: 10.3390/molecules28010175 |
0.626 |
|
| 2022 |
Alarcón-Alarcón D, Cabañero D, de Andrés-López J, Nikolaeva-Koleva M, Giorgi S, Fernández-Ballester G, Fernández-Carvajal A, Ferrer-Montiel A. TRPM8 contributes to sex dimorphism by promoting recovery of normal sensitivity in a mouse model of chronic migraine. Nature Communications. 13: 6304. PMID 36272975 DOI: 10.1038/s41467-022-33835-3 |
0.649 |
|
| 2022 |
Cabañero D, Villalba-Riquelme E, Fernández-Ballester G, Fernández-Carvajal A, Ferrer-Montiel A. ThermoTRP channels in pain sexual dimorphism: new insights for drug intervention. Pharmacology & Therapeutics. 240: 108297. PMID 36202261 DOI: 10.1016/j.pharmthera.2022.108297 |
0.703 |
|
| 2022 |
Fernández-Carvajal A, Fernández-Ballester G, Ferrer-Montiel A. TRPV1 in chronic pruritus and pain: Soft modulation as a therapeutic strategy. Frontiers in Molecular Neuroscience. 15: 930964. PMID 36117910 DOI: 10.3389/fnmol.2022.930964 |
0.694 |
|
| 2022 |
Martín-Escura C, Medina-Peris A, Spear LA, de la Torre Martínez R, Olivos-Oré LA, Barahona MV, González-Rodríguez S, Fernández-Ballester G, Fernández-Carvajal A, Artalejo AR, Ferrer-Montiel A, González-Muñiz R. β-Lactam TRPM8 Antagonist RGM8-51 Displays Antinociceptive Activity in Different Animal Models. International Journal of Molecular Sciences. 23. PMID 35269831 DOI: 10.3390/ijms23052692 |
0.731 |
|
| 2022 |
Villalba-Riquelme E, de la Torre-Martínez R, Fernández-Carvajal A, Ferrer-Montiel A. Paclitaxel in vitro reversibly sensitizes the excitability of IB4(-) and IB4(+) sensory neurons from male and female rats. British Journal of Pharmacology. PMID 35102580 DOI: 10.1111/bph.15809 |
0.76 |
|
| 2021 |
Butrón D, Zamora-Carreras H, Devesa I, Treviño MA, Abian O, Velázquez-Campoy A, Bonache MÁ, Lagartera L, Martín-Martínez M, González-Rodríguez S, Baamonde A, Fernández-Carvajal A, Ferrer-Montiel A, Jiménez MÁ, González-Muñiz R. DD04107-Derived neuronal exocytosis inhibitor peptides: Evidences for synaptotagmin-1 as a putative target. Bioorganic Chemistry. 115: 105231. PMID 34388485 DOI: 10.1016/j.bioorg.2021.105231 |
0.667 |
|
| 2021 |
Journigan VB, Alarcón-Alarcón D, Feng Z, Wang Y, Liang T, Dawley DC, Amin ARMR, Montano C, Van Horn WD, Xie XQ, Ferrer-Montiel A, Fernández-Carvajal A. Structural and in Vitro Functional Characterization of a Menthyl TRPM8 Antagonist Indicates Species-Dependent Regulation. Acs Medicinal Chemistry Letters. 12: 758-767. PMID 34055223 DOI: 10.1021/acsmedchemlett.1c00001 |
0.652 |
|
| 2021 |
Bonache MÁ, Llabrés PJ, Martín-Escura C, De la Torre-Martínez R, Medina-Peris A, Butrón L, Gómez-Monterrey I, Roa AM, Fernández-Ballester G, Ferrer-Montiel A, Fernández-Carvajal A, González-Muñiz R. Phenylalanine-Derived β-Lactam TRPM8 Modulators. Configuration Effect on the Antagonist Activity. International Journal of Molecular Sciences. 22. PMID 33673444 DOI: 10.3390/ijms22052370 |
0.827 |
|
| 2021 |
Nikolaeva-Koleva M, Butron L, González-Rodríguez S, Devesa I, Valente P, Serafini M, Genazzani AA, Pirali T, Ballester GF, Fernández-Carvajal A, Ferrer-Montiel A. A capsaicinoid-based soft drug, AG1529, for attenuating TRPV1-mediated histaminergic and inflammatory sensory neuron excitability. Scientific Reports. 11: 246. PMID 33420359 DOI: 10.1038/s41598-020-80725-z |
0.716 |
|
| 2020 |
Dionisi M, Ruffinatti FA, Riva B, Lim D, Canta A, Meregalli C, Fumagalli G, Monza L, Ferrer-Montiel A, Fernandez-Carvajal A, Cavaletti G, Genazzani AA, Distasi C. Early Stimulation of TREK Channel Transcription and Activity Induced by Oxaliplatin-Dependent Cytosolic Acidification. International Journal of Molecular Sciences. 21. PMID 32998392 DOI: 10.3390/ijms21197164 |
0.732 |
|
| 2020 |
Fernández-Ballester G, Fernández-Carvajal A, Ferrer-Montiel A. Targeting thermoTRP ion channels: preclinical approaches and opportunities. Expert Opinion On Therapeutic Targets. 1-19. PMID 32972264 DOI: 10.1080/14728222.2020.1820987 |
0.733 |
|
| 2020 |
Fernández-Carvajal A, González-Muñiz R, Fernández-Ballester G, Ferrer-Montiel A. Investigational drugs in early phase clinical trials targeting thermotransient receptor potential (thermoTRP) channels. Expert Opinion On Investigational Drugs. PMID 32941080 DOI: 10.1080/13543784.2020.1825680 |
0.739 |
|
| 2020 |
Bonache MÁ, Martín-Escura C, de la Torre Martínez R, Medina A, González-Rodríguez S, Francesch A, Cuevas C, Roa AM, Fernández-Ballester G, Ferrer-Montiel A, Fernández-Carvajal A, González-Muñiz R. Highly functionalized β-lactams and 2-ketopiperazines as TRPM8 antagonists with antiallodynic activity. Scientific Reports. 10: 14154. PMID 32843690 DOI: 10.1038/S41598-020-70691-X |
0.707 |
|
| 2020 |
Cabañero D, Ramírez-López A, Drews E, Schmöle A, Otte DM, Wawrzczak-Bargiela A, Huerga Encabo H, Kummer S, Ferrer-Montiel A, Przewlocki R, Zimmer A, Maldonado R. Protective role of neuronal and lymphoid cannabinoid CB receptors in neuropathic pain. Elife. 9. PMID 32687056 DOI: 10.7554/Elife.55582 |
0.358 |
|
| 2020 |
Cabañero D, Ramírez-López A, Drews E, Schmöle A, Otte DM, Wawrzczak-Bargiela A, Encabo HH, Kummer S, Ferrer-Montiel A, Przewlocki R, Zimmer A, Maldonado R. Author response: Protective role of neuronal and lymphoid cannabinoid CB2 receptors in neuropathic pain Elife. DOI: 10.7554/Elife.55582.Sa2 |
0.364 |
|
| 2019 |
Journigan VB, Feng Z, Rahman S, Wang Y, Amin ARMR, Heffner CE, Bachtel N, Wang S, Gonzalez-Rodriguez S, Fernández-Carvajal A, Fernández-Ballester G, Hilton JK, Van Horn WD, Ferrer-Montiel A, Xie XQ, et al. Structure-based design of novel biphenyl amide antagonists of human Transient Receptor Potential Cation Channel Subfamily M Member 8 channels (TRPM8) with potential implications in the treatment of sensory neuropathies. Acs Chemical Neuroscience. PMID 31850745 DOI: 10.1021/Acschemneuro.9B00404 |
0.732 |
|
| 2019 |
Gonzalez Gil I, Zian D, Vázquez-Villa H, Hernandez-Torres G, Martinez RF, Khiar-Fernandez N, Rivera R, Kihara Y, Devesa I, Mathivanan S, Rosell Del Valle C, Zambrana-Infantes E, Puigdomenech M, Cincilla G, Sanchez-Martinez M, ... ... Ferrer-Montiel A, et al. A novel agonist of the type 1 lysophosphatidic acid receptor (LPA1), UCM-05194, shows efficacy in neuropathic pain amelioration. Journal of Medicinal Chemistry. PMID 31790581 DOI: 10.1021/Acs.Jmedchem.9B01287 |
0.652 |
|
| 2019 |
Pérez de Vega MJ, Fernández-Mendívil C, de la Torre-Martinez R, González-Rodríguez S, Mulet J, Sala F, Sala S, Criado M, Moreno-Fernandez S, Miguel M, Fernández-Carvajal A, Ferrer-Montiel A, López MG, González-Muñiz R. 1-(2',5'-Dihydroxyphenyl)-3-(2-fluoro-4-hydroxyphenyl)-1-propanone (RGM079): A positive allosteric modulator of α7 nicotinic receptors with analgesic and neuroprotective activity. Acs Chemical Neuroscience. PMID 31322853 DOI: 10.1021/Acschemneuro.9B00364 |
0.803 |
|
| 2019 |
Solé L, Roig SR, Sastre D, Vallejo-Gracia A, Serrano-Albarrás A, Ferrer-Montiel A, Fernández-Ballester G, Tamkun MM, Felipe A. The calmodulin-binding tetraleucine motif of KCNE4 is responsible for association with Kv1.3. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201801164RR. PMID 30969795 DOI: 10.1096/Fj.201801164Rr |
0.426 |
|
| 2019 |
Arribas-Blázquez M, Olivos-Oré LA, Barahona MV, Sánchez de la Muela M, Solar V, Jiménez E, Gualix J, McIntosh JM, Ferrer-Montiel A, Miras-Portugal MT, Artalejo AR. Overexpression of P2X3 and P2X7 Receptors and TRPV1 Channels in Adrenomedullary Chromaffin Cells in a Rat Model of Neuropathic Pain. International Journal of Molecular Sciences. 20. PMID 30609840 DOI: 10.3390/Ijms20010155 |
0.45 |
|
| 2018 |
Felipe A, Ferrer-Montiel A. The Spanish Ion Channel Initiative (SICI) Consortium: Ten Years (2008⁻2018) of a Network of Excellence on Ion Channel Research. International Journal of Molecular Sciences. 19. PMID 30413029 DOI: 10.3390/Ijms19113514 |
0.404 |
|
| 2018 |
Pérez de Vega MJ, Ferrer-Montiel A, González-Muñiz R. Recent progress in non-opioid analgesic peptides. Archives of Biochemistry and Biophysics. 660: 36-52. PMID 30342013 DOI: 10.1016/J.Abb.2018.10.011 |
0.441 |
|
| 2018 |
Artero-Morales M, González-Rodríguez S, Ferrer-Montiel A. TRP Channels as Potential Targets for Sex-Related Differences in Migraine Pain. Frontiers in Molecular Biosciences. 5: 73. PMID 30155469 DOI: 10.3389/Fmolb.2018.00073 |
0.417 |
|
| 2018 |
Bertamino A, Iraci N, Ostacolo C, Ambrosino P, Musella S, Di Sarno V, Ciaglia T, Pepe G, Sala M, Soldovieri MV, Mosca I, Gonzalez-Rodriguez S, Fernández-Carvajal A, Ferrer-Montiel A, Novellino E, et al. Identification of a Potent Tryptophan-based TRPM8 Antagonist With in vivo Analgesic Activity. Journal of Medicinal Chemistry. PMID 29939028 DOI: 10.1021/Acs.Jmedchem.8B00545 |
0.738 |
|
| 2018 |
Serafini M, Griglio A, Aprile S, Seiti F, Travelli C, Pattarino F, Grosa G, Sorba G, Genazzani AA, Gonzales-Rodriguez S, Butron L, Devesa I, Fernández-Carvajal A, Pirali T, Ferrer-Montiel A. Targeting transient receptor potential vanilloid 1 (TRPV1) channel softly: the discovery of Passerini adducts as a topical treatment for inflammatory skin disorders. Journal of Medicinal Chemistry. PMID 29722529 DOI: 10.1021/Acs.Jmedchem.8B00109 |
0.749 |
|
| 2018 |
Balsera B, Mulet J, Sala S, Sala F, de la Torre-Martínez R, González-Rodríguez S, Plata A, Naesens L, Fernández-Carvajal A, Ferrer-Montiel A, Criado M, Pérez de Vega MJ, González-Muñiz R. Amino acid and peptide prodrugs of diphenylpropanones positive allosteric modulators of α7 nicotinic receptors with analgesic activity. European Journal of Medicinal Chemistry. 143: 157-165. PMID 29174812 DOI: 10.1016/J.Ejmech.2017.10.083 |
0.813 |
|
| 2017 |
Quarta S, Camprubí-Robles M, Schweigreiter R, Matusica D, Haberberger RV, Proia RL, Bandtlow CE, Ferrer-Montiel A, Kress M. Sphingosine-1-Phosphate and the S1P3 Receptor Initiate Neuronal Retraction via RhoA/ROCK Associated with CRMP2 Phosphorylation. Frontiers in Molecular Neuroscience. 10: 317. PMID 29066950 DOI: 10.3389/Fnmol.2017.00317 |
0.309 |
|
| 2017 |
de la Torre-Martínez R, Bonache MA, Llabrés-Campaner PJ, Balsera B, Fernández-Carvajal A, Fernández-Ballester G, Ferrer-Montiel A, Pérez de Vega MJ, González-Muñiz R. Synthesis, high-throughput screening and pharmacological characterization of β-lactam derivatives as TRPM8 antagonists. Scientific Reports. 7: 10766. PMID 28883526 DOI: 10.1038/S41598-017-10913-X |
0.811 |
|
| 2017 |
Ciardo MG, Ferrer-Montiel A. Lipids as central modulators of sensory TRP channels. Biochimica Et Biophysica Acta. PMID 28432033 DOI: 10.1016/J.Bbamem.2017.04.012 |
0.805 |
|
| 2016 |
Mathivanan S, Devesa I, Changeux JP, Ferrer-Montiel A. Bradykinin Induces TRPV1 Exocytotic Recruitment in Peptidergic Nociceptors. Frontiers in Pharmacology. 7: 178. PMID 27445816 DOI: 10.3389/Fphar.2016.00178 |
0.757 |
|
| 2016 |
Pérez de Vega MJ, Gómez-Monterrey I, Ferrer-Montiel A, González-Muñiz R. Transient Receptor Potential Melastatin 8 Channel (TRPM8) Modulation: Cool Entryway for Treating Pain and Cancer. Journal of Medicinal Chemistry. 59: 10006-10029. PMID 27437828 DOI: 10.1021/Acs.Jmedchem.6B00305 |
0.545 |
|
| 2016 |
Criado M, Balsera B, Mulet J, Sala S, Sala F, la Torre-Martínez R, Fernández-Carvajal A, Ferrer-Montiel A, Moreno-Fernández S, Miguel M, Pérez de Vega MJ, González-Muñiz R. 1,3-diphenylpropan-1-ones as allosteric modulators of α7 nACh receptors with analgesic and antioxidant properties. Future Medicinal Chemistry. PMID 27161515 DOI: 10.4155/Fmc-2015-0001 |
0.691 |
|
| 2016 |
Taberner FJ, Devesa I, Ferrer-Montiel A. Calcium Entry Through Thermosensory Channels. Advances in Experimental Medicine and Biology. 898: 265-304. PMID 27161233 DOI: 10.1007/978-3-319-26974-0_12 |
0.756 |
|
| 2016 |
Bertamino A, Ostacolo C, Ambrosino P, Musella S, Di Sarno V, Ciaglia T, Soldovieri MV, Iraci N, Fernandez Carvajal A, de la Torre-Martinez R, Ferrer-Montiel A, Gonzalez Muniz R, Novellino E, Taglialatela M, Campiglia P, et al. Tryptamine-Based Derivatives as Transient Receptor Potential Melastatin Type 8 (TRPM8) Channel Modulators. Journal of Medicinal Chemistry. 59: 2179-91. PMID 26847872 DOI: 10.1021/Acs.Jmedchem.5B01914 |
0.814 |
|
| 2016 |
Pérez-Faginas P, Teresa Aranda M, Torre-Martínez Rdl, Quirce S, Fernández-Carvajal A, Ferrer-Montiel A, González-Muñiz R. New transient receptor potential TRPV1, TRPM8 and TRPA1 channel antagonists from a single linear β,γ-diamino ester scaffold Rsc Advances. 6: 6868-6877. DOI: 10.1039/C5Ra25709C |
0.433 |
|
| 2015 |
de la Peña E, Gomis A, Ferrer-Montiel A, Belmonte C. TRPV1 channel modulation by hyaluronan reduces pain. Channels (Austin, Tex.). 0. PMID 26517313 DOI: 10.1080/19336950.2015.1109300 |
0.465 |
|
| 2015 |
Ciardo MG, Andrés-Bordería A, Cuesta N, Valente P, Camprubí-Robles M, Yang J, Planells-Cases R, Ferrer-Montiel A. Whirlin increases TRPV1 channel expression and cellular stability. Biochimica Et Biophysica Acta. PMID 26516054 DOI: 10.1016/J.Bbamcr.2015.10.016 |
0.781 |
|
| 2015 |
Caires R, Luis E, Taberner FJ, Fernandez-Ballester G, Ferrer-Montiel A, Balazs EA, Gomis A, Belmonte C, de la Peña E. Hyaluronan modulates TRPV1 channel opening, reducing peripheral nociceptor activity and pain. Nature Communications. 6: 8095. PMID 26311398 DOI: 10.1038/Ncomms9095 |
0.786 |
|
| 2015 |
Gregorio-Teruel L, Valente P, Liu B, Fernández-Ballester G, Qin F, Ferrer-Montiel A. The Integrity of the TRP Domain Is Pivotal for Correct TRPV1 Channel Gating. Biophysical Journal. 109: 529-41. PMID 26244735 DOI: 10.1016/J.Bpj.2015.06.039 |
0.482 |
|
| 2015 |
Taberner FJ, Fernández-Ballester G, Fernández-Carvajal A, Ferrer-Montiel A. TRP channels interaction with lipids and its implications in disease. Biochimica Et Biophysica Acta. 1848: 1818-27. PMID 25838124 DOI: 10.1016/J.Bbamem.2015.03.022 |
0.833 |
|
| 2015 |
López-Córdoba A, Jönsson P, Babakinejad B, Actis P, Novak P, Yasufumi T, Shevchuck A, Anand U, Anand P, Drews A, Ferrer-Montiel A, Klenerman D, Korchev Y. SICM-Based Nanodelivery System for Local TRPV1 Stimulation Biophysical Journal. 108: 332a. DOI: 10.1016/J.Bpj.2014.11.1808 |
0.441 |
|
| 2014 |
Devesa I, Ferrándiz-Huertas C, Mathivanan S, Wolf C, Luján R, Changeux JP, Ferrer-Montiel A. αCGRP is essential for algesic exocytotic mobilization of TRPV1 channels in peptidergic nociceptors. Proceedings of the National Academy of Sciences of the United States of America. 111: 18345-50. PMID 25489075 DOI: 10.1073/Pnas.1420252111 |
0.72 |
|
| 2014 |
Fresno N, Pérez-Fernández R, Goicoechea C, Alkorta I, Fernández-Carvajal A, de la Torre-Martínez R, Quirce S, Ferrer-Montiel A, Martín MI, Goya P, Elguero J. Adamantyl analogues of paracetamol as potent analgesic drugs via inhibition of TRPA1. Plos One. 9: e113841. PMID 25438056 DOI: 10.1371/Journal.Pone.0113841 |
0.817 |
|
| 2014 |
Ferrandiz-Huertas C, Mathivanan S, Wolf CJ, Devesa I, Ferrer-Montiel A. Trafficking of ThermoTRP Channels. Membranes. 4: 525-64. PMID 25257900 DOI: 10.3390/membranes4030525 |
0.738 |
|
| 2014 |
Balsera B, Mulet J, Fernández-Carvajal A, de la Torre-Martínez R, Ferrer-Montiel A, Hernández-Jiménez JG, Estévez-Herrera J, Borges R, Freitas AE, López MG, García-López MT, González-Muñiz R, Pérez de Vega MJ, Valor LM, Svobodová L, et al. Chalcones as positive allosteric modulators of α7 nicotinic acetylcholine receptors: a new target for a privileged structure. European Journal of Medicinal Chemistry. 86: 724-39. PMID 25232969 DOI: 10.1016/J.Ejmech.2014.09.039 |
0.805 |
|
| 2014 |
Taberner FJ, López-Córdoba A, Fernández-Ballester G, Korchev Y, Ferrer-Montiel A. The region adjacent to the C-end of the inner gate in transient receptor potential melastatin 8 (TRPM8) channels plays a central role in allosteric channel activation. The Journal of Biological Chemistry. 289: 28579-94. PMID 25157108 DOI: 10.1074/Jbc.M114.577478 |
0.774 |
|
| 2014 |
Bonache MÁ, Balsera B, López-Méndez B, Millet O, Brancaccio D, Gómez-Monterrey I, Carotenuto A, Pavone LM, Reille-Seroussi M, Gagey-Eilstein N, Vidal M, de la Torre-Martinez R, Fernández-Carvajal A, Ferrer-Montiel A, García-López MT, et al. De novo designed library of linear helical peptides: an exploratory tool in the discovery of protein-protein interaction modulators. Acs Combinatorial Science. 16: 250-8. PMID 24725184 DOI: 10.1021/Co500005X |
0.759 |
|
| 2014 |
Gregorio-Teruel L, Valente P, González-Ros JM, Fernández-Ballester G, Ferrer-Montiel A. Mutation of I696 and W697 in the TRP box of vanilloid receptor subtype I modulates allosteric channel activation. The Journal of General Physiology. 143: 361-75. PMID 24567510 DOI: 10.1085/Jgp.201311070 |
0.515 |
|
| 2014 |
Devesa I, Ferrer-Montiel A. Neurotrophins, endocannabinoids and thermo-transient receptor potential: a threesome in pain signalling. The European Journal of Neuroscience. 39: 353-62. PMID 24494676 DOI: 10.1111/Ejn.12455 |
0.356 |
|
| 2013 |
Martínez-Mármol R, Pérez-Verdaguer M, Roig SR, Vallejo-Gracia A, Gotsi P, Serrano-Albarrás A, Bahamonde MI, Ferrer-Montiel A, Fernández-Ballester G, Comes N, Felipe A. A non-canonical di-acidic signal at the C-terminus of Kv1.3 determines anterograde trafficking and surface expression. Journal of Cell Science. 126: 5681-91. PMID 24144698 DOI: 10.1242/Jcs.134825 |
0.463 |
|
| 2013 |
Bavassano C, Marvaldi L, Langeslag M, Sarg B, Lindner H, Klimaschewski L, Kress M, Ferrer-Montiel A, Knaus HG. Identification of voltage-gated K(+) channel beta 2 (Kvβ2) subunit as a novel interaction partner of the pain transducer Transient Receptor Potential Vanilloid 1 channel (TRPV1). Biochimica Et Biophysica Acta. 1833: 3166-75. PMID 24036102 DOI: 10.1016/J.Bbamcr.2013.09.001 |
0.528 |
|
| 2013 |
Babakinejad B, Jönsson P, López Córdoba A, Actis P, Novak P, Takahashi Y, Shevchuk A, Anand U, Anand P, Drews A, Ferrer-Montiel A, Klenerman D, Korchev YE. Local delivery of molecules from a nanopipette for quantitative receptor mapping on live cells. Analytical Chemistry. 85: 9333-42. PMID 24004146 DOI: 10.1021/Ac4021769 |
0.359 |
|
| 2013 |
Belghiti M, Estévez-Herrera J, Giménez-Garzó C, González-Usano A, Montoliu C, Ferrer-Montiel A, Felipo V, Planells-Cases R. Potentiation of the transient receptor potential vanilloid 1 channel contributes to pruritogenesis in a rat model of liver disease. The Journal of Biological Chemistry. 288: 9675-85. PMID 23408423 DOI: 10.1074/Jbc.M113.455162 |
0.433 |
|
| 2013 |
Pérez-Faginas P, Aranda MT, García-López MT, Infantes L, Fernández-Carvajal A, González-Ros JM, Ferrer-Montiel A, González-Muñiz R. Highly functionalized 1,2-diamino compounds through reductive amination of amino acid-derived β-keto esters. Plos One. 8: e53231. PMID 23308167 DOI: 10.1371/Journal.Pone.0053231 |
0.66 |
|
| 2013 |
Taberner FJ, López-Córdoba A, Fernández-Ballester G, Korchev Y, Ferrer-Montiel A. Mutations in the TRP Domain Differentially affect the Function of TRPM8 Biophysical Journal. 104: 4-6. DOI: 10.1016/J.Bpj.2012.11.2521 |
0.506 |
|
| 2013 |
Moiseenkova-Bell VY, Cvetkov TL, Wang L, Huynh KW, Fernandez-Ballester G, Chakrapani S, Ferrer-Montiel A, Chance MR. Structural Insights into the Dynamics of the TRPA1 Activation Mechanism Biophysical Journal. 104: 377a-378a. DOI: 10.1016/J.Bpj.2012.11.2103 |
0.509 |
|
| 2012 |
Ferrer-Montiel A, Fernández-Carvajal A, Planells-Cases R, Fernández-Ballester G, González-Ros JM, Messeguer A, González-Muñiz R. Advances in modulating thermosensory TRP channels. Expert Opinion On Therapeutic Patents. 22: 999-1017. PMID 22835143 DOI: 10.1517/13543776.2012.711320 |
0.759 |
|
| 2012 |
Sanz-Salvador L, Andrés-Borderia A, Ferrer-Montiel A, Planells-Cases R. Agonist- and Ca2+-dependent desensitization of TRPV1 channel targets the receptor to lysosomes for degradation. The Journal of Biological Chemistry. 287: 19462-71. PMID 22493457 DOI: 10.1074/Jbc.M111.289751 |
0.5 |
|
| 2012 |
Ponsati B, Carreño C, Curto-Reyes V, Valenzuela B, Duart MJ, Van den Nest W, Cauli O, Beltran B, Fernandez J, Borsini F, Caprioli A, Di Serio S, Veretchy M, Baamonde A, Menendez L, ... ... Ferrer-Montiel A, et al. An inhibitor of neuronal exocytosis (DD04107) displays long-lasting in vivo activity against chronic inflammatory and neuropathic pain. The Journal of Pharmacology and Experimental Therapeutics. 341: 634-45. PMID 22393248 DOI: 10.1124/Jpet.111.190678 |
0.423 |
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| 2011 |
Fernández-Ballester G, Fernández-Carvajal A, González-Ros JM, Ferrer-Montiel A. Ionic channels as targets for drug design: a review on computational methods. Pharmaceutics. 3: 932-53. PMID 24309315 DOI: 10.3390/Pharmaceutics3040932 |
0.743 |
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| 2011 |
Fernández-Carvajal A, Fernández-Ballester G, Devesa I, González-Ros JM, Ferrer-Montiel A. New strategies to develop novel pain therapies: addressing thermoreceptors from different points of view. Pharmaceuticals (Basel, Switzerland). 5: 16-48. PMID 24288041 DOI: 10.3390/Ph5010016 |
0.776 |
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| 2011 |
Devesa I, Planells-Cases R, Fernández-Ballester G, González-Ros JM, Ferrer-Montiel A, Fernández-Carvajal A. Role of the transient receptor potential vanilloid 1 in inflammation and sepsis. Journal of Inflammation Research. 4: 67-81. PMID 22096371 DOI: 10.2147/Jir.S12978 |
0.746 |
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| 2011 |
Vidal-Mosquera M, Fernández-Carvajal A, Moure A, Valente P, Planells-Cases R, González-Ros JM, Bujons J, Ferrer-Montiel A, Messeguer A. Triazine-based vanilloid 1 receptor open channel blockers: design, synthesis, evaluation, and SAR analysis. Journal of Medicinal Chemistry. 54: 7441-52. PMID 21950613 DOI: 10.1021/Jm200981S |
0.784 |
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| 2011 |
Gerona-Navarro G, González-Muñiz R, Fernández-Carvajal A, González-Ros JM, Ferrer-Montiel A, Carreño C, Albericio F, Royo M. Solid-phase synthesis of a library of amphipatic hydantoins. Discovery of new hits for TRPV1 blockade. Acs Combinatorial Science. 13: 458-65. PMID 21671576 DOI: 10.1021/Co1000986 |
0.722 |
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| 2011 |
Zaccaro L, García-López MT, González-Muñiz R, García-Martínez C, Ferrer-Montiel A, Albericio F, Royo M. TRPV1 modulators: structure-activity relationships using a rational combinatorial approach. Bioorganic & Medicinal Chemistry Letters. 21: 3541-5. PMID 21612926 DOI: 10.1016/J.Bmcl.2011.04.141 |
0.339 |
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| 2011 |
Goswami C, Kuhn J, Dina OA, Fernández-Ballester G, Levine JD, Ferrer-Montiel A, Hucho T. Estrogen destabilizes microtubules through an ion-conductivity-independent TRPV1 pathway. Journal of Neurochemistry. 117: 995-1008. PMID 21480900 DOI: 10.1111/J.1471-4159.2011.07270.X |
0.405 |
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| 2011 |
Valente P, Fernández-Carvajal A, CamprubÃ-Robles M, Gomis A, Quirce S, Viana F, Fernández-Ballester G, González-Ros JM, Belmonte C, Planells-Cases R, Ferrer-Montiel A. Membrane-tethered peptides patterned after the TRP domain (TRPducins) selectively inhibit TRPV1 channel activity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1628-40. PMID 21307333 DOI: 10.1096/Fj.10-174433 |
0.773 |
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| 2011 |
Planells-Cases R, Valente P, Ferrer-Montiel A, Qin F, Szallasi A. Complex regulation of TRPV1 and related thermo-TRPs: implications for therapeutic intervention. Advances in Experimental Medicine and Biology. 704: 491-515. PMID 21290313 DOI: 10.1007/978-94-007-0265-3_27 |
0.481 |
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| 2011 |
Ferrándiz-Huertas C, Fernández-Carvajal A, Ferrer-Montiel A. Rab4 interacts with the human P-glycoprotein and modulates its surface expression in multidrug resistant K562 cells. International Journal of Cancer. 128: 192-205. PMID 20209493 DOI: 10.1002/Ijc.25310 |
0.647 |
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| 2010 |
Pérez de Vega MJ, García-López MT, Zaccaro L, Royo M, Albericio F, Fernández-Carvajal A, Ferrer-Montiel A, González-Muñiz R. Solid-phase synthesis of new Trp(Nps)-containing dipeptide derivatives as TRPV1 channel blockers. Molecules (Basel, Switzerland). 15: 4924-33. PMID 20657400 DOI: 10.3390/Molecules15074924 |
0.713 |
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| 2010 |
Lainez S, Valente P, Ontoria-Oviedo I, Estevez-Herrera J, Camprubi-Robles M, Ferrer-Montiel A, Planells-Cases R. GABAA receptor associated protein (GABARAP) modulates TRPV1 expression and channel function and desensitization The Faseb Journal. 24: 1958-1970. PMID 20179142 DOI: 10.1096/Fj.09-151472 |
0.502 |
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| 2010 |
Camprubí-Robles M, Ferrer-Montiel A, Planells-Cases R. Contribution of Ion Channel Trafficking to Nociceptor Sensitization The Open Pain Journal. 3: 108-116. DOI: 10.2174/1876386301003010108 |
0.459 |
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| 2009 |
Viana F, Ferrer-Montiel A. TRPA1 modulators in preclinical development. Expert Opinion On Therapeutic Patents. 19: 1787-99. PMID 19939193 DOI: 10.1517/13543770903393771 |
0.429 |
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| 2009 |
Malkia A, Pertusa M, Fernández-Ballester G, Ferrer-Montiel A, Viana F. Differential role of the menthol-binding residue Y745 in the antagonism of thermally gated TRPM8 channels. Molecular Pain. 5: 62. PMID 19886999 DOI: 10.1186/1744-8069-5-62 |
0.537 |
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| 2009 |
Camprubí-Robles M, Planells-Cases R, Ferrer-Montiel A. Differential contribution of SNARE-dependent exocytosis to inflammatory potentiation of TRPV1 in nociceptors The Faseb Journal. 23: 3722-3733. PMID 19584302 DOI: 10.1096/Fj.09-134346 |
0.485 |
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| 2009 |
Ferrer-Montiel A, Camprubí-Robles M, García-Sanz N, Sempere A, Valente P, Nest WVD, Carreño C. The contribution of neurogenic inflammation to sensitive skin: concepts, mechanisms and cosmeceutical intervention International Journal of Cosmetic Science. 31: 477-477. DOI: 10.1111/J.1468-2494.2009.00530_1.X |
0.347 |
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| 2008 |
Messeguer J, Cortés N, García-Sanz N, Navarro-Vendrell G, Ferrer-Montiel A, Messeguer A. Synthesis of a positional scanning library of pentamers of N-alkylglycines assisted by microwave activation and validation via the identification of trypsin inhibitors. Journal of Combinatorial Chemistry. 10: 974-80. PMID 18847288 DOI: 10.1021/Cc800144X |
0.35 |
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| 2008 |
Fernández-Ballester G, Ferrer-Montiel A. Molecular Modeling of the Full-length Human TRPV1 Channel in Closed and Desensitized States The Journal of Membrane Biology. 223: 161-172. PMID 18791833 DOI: 10.1007/S00232-008-9123-7 |
0.494 |
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| 2008 |
Kress M, Karasek J, Ferrer-Montiel AV, Scherbakov N, Haberberger RV. TRPC channels and diacylglycerol dependent calcium signaling in rat sensory neurons. Histochemistry and Cell Biology. 130: 655-67. PMID 18663462 DOI: 10.1007/S00418-008-0477-9 |
0.358 |
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| 2008 |
Valente P, GarcÃa-Sanz N, Gomis A, Fernández-Carvajal A, Fernández-Ballester G, Viana F, Belmonte C, Ferrer-Montiel A. Identification of molecular determinants of channel gating in the transient receptor potential box of vanilloid receptor I. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3298-309. PMID 18559878 DOI: 10.1096/Fj.08-107425 |
0.773 |
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| 2007 |
Planells-Cases1 R, Ferrer-Montiel A. Drug design and development through the vanilloid receptor. Expert Opinion On Drug Discovery. 2: 1053-63. PMID 23484872 DOI: 10.1517/17460441.2.8.1053 |
0.402 |
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| 2007 |
Quintanar-Audelo M, Fernández-Carvajal A, Van Den Nest W, Carreño C, Ferrer-Montiel A, Albericio F. Design and synthesis of indole-based peptoids as potent noncompetitive antagonists of transient receptor potential vanilloid 1. Journal of Medicinal Chemistry. 50: 6133-43. PMID 17985859 DOI: 10.1021/Jm070612V |
0.737 |
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| 2007 |
GarcÃa-Sanz N, Valente P, Gomis A, Fernández-Carvajal A, Fernández-Ballester G, Viana F, Belmonte C, Ferrer-Montiel A. A role of the transient receptor potential domain of vanilloid receptor I in channel gating. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11641-50. PMID 17959807 DOI: 10.1523/Jneurosci.2457-07.2007 |
0.77 |
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| 2006 |
Messeguer A, Planells-Cases R, Ferrer-Montiel A. Physiology and pharmacology of the vanilloid receptor. Current Neuropharmacology. 4: 1-15. PMID 18615132 DOI: 10.2174/157015906775202995 |
0.515 |
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| 2006 |
Planells-Cases R, Lerma J, Ferrer-Montiel A. Pharmacological intervention at ionotropic glutamate receptor complexes. Current Pharmaceutical Design. 12: 3583-96. PMID 17073661 DOI: 10.2174/138161206778522092 |
0.365 |
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| 2006 |
GarcÃa-MartÃnez C, Fernández-Carvajal A, Valenzuela B, Gomis A, Van Den Nest W, Ferroni S, Carreño C, Belmonte C, Ferrer-Montiel A. Design and characterization of a noncompetitive antagonist of the transient receptor potential vanilloid subunit 1 channel with in vivo analgesic and anti-inflammatory activity. The Journal of Pain : Official Journal of the American Pain Society. 7: 735-46. PMID 17018334 DOI: 10.1016/J.Jpain.2006.03.008 |
0.753 |
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| 2006 |
Bonache MA, García-Martínez C, García de Diego L, Carreño C, Pérez de Vega MJ, García-López MT, Ferrer-Montiel A, González-Muñiz R. Old molecules for new receptors: Trp(Nps) dipeptide derivatives as vanilloid TRPV1 channel blockers. Chemmedchem. 1: 429-38. PMID 16892378 DOI: 10.1002/cmdc.200500094 |
0.381 |
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| 2006 |
Carteron C, Ferrer-Montiel A, Cabedo H. Characterization of a neural-specific splicing form of the human neuregulin 3 gene involved in oligodendrocyte survival. Journal of Cell Science. 119: 898-909. PMID 16478787 DOI: 10.1242/Jcs.02799 |
0.312 |
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| 2006 |
Malet G, Martín AG, Orzáez M, Vicent MJ, Masip I, Sanclimens G, Ferrer-Montiel A, Mingarro I, Messeguer A, Fearnhead HO, Pérez-Payá E. Small molecule inhibitors of Apaf-1-related caspase- 3/-9 activation that control mitochondrial-dependent apoptosis. Cell Death and Differentiation. 13: 1523-32. PMID 16341125 DOI: 10.1038/Sj.Cdd.4401828 |
0.309 |
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| 2005 |
Planells-Cases R, Garcìa-Sanz N, Morenilla-Palao C, Ferrer-Montiel A. Functional aspects and mechanisms of TRPV1 involvement in neurogenic inflammation that leads to thermal hyperalgesia. Pflugers Archiv : European Journal of Physiology. 451: 151-9. PMID 15909179 DOI: 10.1007/S00424-005-1423-5 |
0.464 |
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| 2005 |
Caprini M, Fava M, Valente P, Fernandez-Ballester G, Rapisarda C, Ferroni S, Ferrer-Montiel A. Molecular compatibility of the channel gate and the N terminus of S5 segment for voltage-gated channel activity. The Journal of Biological Chemistry. 280: 18253-64. PMID 15749711 DOI: 10.1074/Jbc.M413389200 |
0.456 |
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| 2004 |
Pastor MT, Mora P, Ferrer-Montiel A, Pérez-Payá E. Design of bioactive and structurally well-defined peptides from conformationally restricted libraries. Biopolymers. 76: 357-65. PMID 15386263 DOI: 10.1002/Bip.20142 |
0.308 |
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| 2004 |
García-Sanz N, Fernández-Carvajal A, Morenilla-Palao C, Planells-Cases R, Fajardo-Sánchez E, Fernández-Ballester G, Ferrer-Montiel A. Identification of a tetramerization domain in the C terminus of the vanilloid receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5307-14. PMID 15190102 DOI: 10.1523/Jneurosci.0202-04.2004 |
0.722 |
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| 2004 |
Ferrer-Montiel A, García-Martínez C, Morenilla-Palao C, García-Sanz N, Fernández-Carvajal A, Fernández-Ballester G, Planells-Cases R. Molecular architecture of the vanilloid receptor. Insights for drug design. European Journal of Biochemistry. 271: 1820-6. PMID 15128292 DOI: 10.1111/j.1432-1033.2004.04083.x |
0.742 |
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| 2004 |
Morenilla-Palao C, Planells-Cases R, García-Sanz N, Ferrer-Montiel A. Regulated exocytosis contributes to protein kinase C potentiation of vanilloid receptor activity. The Journal of Biological Chemistry. 279: 25665-72. PMID 15066994 DOI: 10.1074/Jbc.M311515200 |
0.534 |
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| 2004 |
Masip I, Ferrándiz-Huertas C, García-Martínez C, Ferragut JA, Ferrer-Montiel A, Messeguer A. Synthesis of a library of 3-oxopiperazinium and perhydro-3-oxo-1,4-diazepinium derivatives and identification of bioactive compounds. Journal of Combinatorial Chemistry. 6: 135-41. PMID 14714997 DOI: 10.1021/Cc030002Q |
0.347 |
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| 2004 |
Blanes-Mira C, Merino JM, Valera E, Fernández-Ballester G, Gutiérrez LM, Viniegra S, Pérez-Payá E, Ferrer-Montiel A. Small peptides patterned after the N-terminus domain of SNAP25 inhibit SNARE complex assembly and regulated exocytosis. Journal of Neurochemistry. 88: 124-35. PMID 14675156 DOI: 10.1046/J.1471-4159.2003.02133.X |
0.321 |
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| 2003 |
Planells-Cases R, Pérez-Payá E, Messeguer A, Carreño C, Ferrer-Montiel A. Small molecules targeting the NMDA receptor complex as drugs for neuropathic pain. Mini Reviews in Medicinal Chemistry. 3: 749-56. PMID 14529515 DOI: 10.2174/1389557033487782 |
0.346 |
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| 2003 |
Blanes-Mira C, Pastor MT, Valera E, Fernández-Ballester G, Merino JM, Gutierrez LM, Perez-Payá E, Ferrer-Montiel A. Identification of SNARE complex modulators that inhibit exocytosis from an alpha-helix-constrained combinatorial library. The Biochemical Journal. 375: 159-66. PMID 12852787 DOI: 10.1042/Bj20030509 |
0.329 |
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| 2002 |
Valera E, Fernández-Salguero PM, Planells-Cases R, Messeguer A, Van Den Nest W, Carreño C, Ferrer-Montiel A, Merino JM. Neuroprotection against excitotoxicity by N-alkylglycines in rat hippocampal neurons. Neuromolecular Medicine. 2: 271-80. PMID 12622405 DOI: 10.1385/Nmm:2:3:271 |
0.324 |
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| 2002 |
Planells-Cases R, Montoliu C, Humet M, Fernández AM, García-Martínez C, Valera E, Merino JM, Pérez-Payá E, Messeguer A, Felipo V, Ferrer-Montiel A. A novel N-methyl-D-aspartate receptor open channel blocker with in vivo neuroprotectant activity. The Journal of Pharmacology and Experimental Therapeutics. 302: 163-73. PMID 12065713 DOI: 10.1124/Jpet.302.1.163 |
0.417 |
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| 2002 |
Montoliu C, Humet M, Canales JJ, Burda J, Planells-Cases R, Sánchez-Baeza F, Carbonell T, Pérez-Payá E, Messeguer A, Ferrer-Montiel A, Felipo V. Prevention of in vivo excitotoxicity by a family of trialkylglycines, a novel class of neuroprotectants. The Journal of Pharmacology and Experimental Therapeutics. 301: 29-36. PMID 11907154 DOI: 10.1124/Jpet.301.1.29 |
0.369 |
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| 2002 |
Cabedo H, Luna C, Fernandez AM, Gallar J, Ferrer-Montiel A. Molecular determinants of the sensory and motor neuron-derived factor insertion into plasma membrane. The Journal of Biological Chemistry. 277: 19905-12. PMID 11896060 DOI: 10.1074/Jbc.M201587200 |
0.301 |
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| 2002 |
GarcÃa-Martinez C, Humet M, Planells-Cases R, Gomis A, Caprini M, Viana F, De La Pena E, Sanchez-Baeza F, Carbonell T, De Felipe C, Pérez-Paya E, Belmonte C, Messeguer A, Ferrer-Montiel A. Attenuation of thermal nociception and hyperalgesia by VR1 blockers. Proceedings of the National Academy of Sciences of the United States of America. 99: 2374-9. PMID 11854530 DOI: 10.1073/Pnas.022285899 |
0.435 |
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| 2001 |
Caprini M, Ferroni S, Planells-Cases R, Rueda J, Rapisarda C, Ferrer-Montiel A, Montal M. Structural compatibility between the putative voltage sensor of voltage-gated K+ channels and the prokaryotic KcsA channel. The Journal of Biological Chemistry. 276: 21070-6. PMID 11274182 DOI: 10.1074/Jbc.M100487200 |
0.673 |
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| 1998 |
Encinar JA, Fernández A, Ferragut JA, González-Ros JM, DasGupta BR, Montal M, Ferrer-Montiel A. Structural stabilization of botulinum neurotoxins by tyrosine phosphorylation. Febs Letters. 429: 78-82. PMID 9657387 DOI: 10.1016/S0014-5793(98)00571-7 |
0.508 |
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