Tsuyoshi Hirota, PhD - Publications

Affiliations: 
Biology University of California, San Diego, La Jolla, CA 
Area:
Circadian Rhythms

35/249 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Mosser EA, Chiu CN, Tamai TK, Hirota T, Li S, Hui M, Wang A, Singh C, Giovanni A, Kay SA, Prober DA. Identification of pathways that regulate circadian rhythms using a larval zebrafish small molecule screen. Scientific Reports. 9: 12405. PMID 31455847 DOI: 10.1038/s41598-019-48914-7  1
2019 Uehara TN, Mizutani Y, Kuwata K, Hirota T, Sato A, Mizoi J, Takao S, Matsuo H, Suzuki T, Ito S, Saito AN, Nishiwaki-Ohkawa T, Yamaguchi-Shinozaki K, Yoshimura T, Kay SA, et al. Casein kinase 1 family regulates PRR5 and TOC1 in the Arabidopsis circadian clock. Proceedings of the National Academy of Sciences of the United States of America. PMID 31097584 DOI: 10.1073/pnas.1903357116  1
2019 Oshima T, Niwa Y, Kuwata K, Srivastava A, Hyoda T, Tsuchiya Y, Kumagai M, Tsuyuguchi M, Tamaru T, Sugiyama A, Ono N, Zolboot N, Aikawa Y, Oishi S, Nonami A, ... ... Hirota T, et al. Cell-based screen identifies a new potent and highly selective CK2 inhibitor for modulation of circadian rhythms and cancer cell growth. Science Advances. 5: eaau9060. PMID 30746467 DOI: 10.1126/sciadv.aau9060  1
2019 Lee JW, Hirota T, Ono D, Honma S, Honma KI, Park K, Kay S. Chemical Control of Mammalian Circadian Behavior through Dual Inhibition of Casein Kinase Iα and δ. Journal of Medicinal Chemistry. PMID 30707835 DOI: 10.1021/acs.jmedchem.8b01541  1
2018 Qu M, Duffy T, Hirota T, Kay SA. Nuclear receptor HNF4A transrepresses CLOCK:BMAL1 and modulates tissue-specific circadian networks. Proceedings of the National Academy of Sciences of the United States of America. PMID 30530698 DOI: 10.1073/pnas.1816411115  1
2016 Zhao X, Hirota T, Han X, Cho H, Chong LW, Lamia K, Liu S, Atkins AR, Banayo E, Liddle C, Yu RT, Yates JR, Kay SA, Downes M, Evans RM. Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation. Cell. 165: 1644-57. PMID 27238018 DOI: 10.1016/j.cell.2016.05.012  1
2015 Lee JW, Hirota T, Kumar A, Kim NJ, Irle S, Kay SA. Development of Small-Molecule Cryptochrome Stabilizer Derivatives as Modulators of the Circadian Clock. Chemmedchem. 10: 1489-97. PMID 26174033 DOI: 10.1002/cmdc.201500260  1
2015 Oshima T, Yamanaka I, Kumar A, Yamaguchi J, Nishiwaki-Ohkawa T, Muto K, Kawamura R, Hirota T, Yagita K, Irle S, Kay SA, Yoshimura T, Itami K. C-H activation generates period-shortening molecules that target cryptochrome in the mammalian circadian clock. Angewandte Chemie (International Ed. in English). 54: 7193-7. PMID 25960183 DOI: 10.1002/anie.201502942  1
2015 Hirota T, Kay SA. Identification of small-molecule modulators of the circadian clock. Methods in Enzymology. 551: 267-82. PMID 25662461 DOI: 10.1016/bs.mie.2014.10.015  1
2015 Paternoster L, Standl M, Waage J, Baurecht H, Hotze M, Strachan DP, Curtin JA, Bønnelykke K, Tian C, Takahashi A, Esparza-Gordillo J, Alves AC, Thyssen JP, Den Dekker HT, Ferreira MA, ... ... Hirota T, et al. Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis Nature Genetics. 47: 1449-1456. DOI: 10.1038/ng.3424  1
2014 Hirano A, Kurabayashi N, Nakagawa T, Shioi G, Todo T, Hirota T, Fukada Y. In vivo role of phosphorylation of cryptochrome 2 in the mouse circadian clock. Molecular and Cellular Biology. 34: 4464-73. PMID 25288642 DOI: 10.1128/MCB.00711-14  1
2014 St John PC, Hirota T, Kay SA, Doyle FJ. Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock. Proceedings of the National Academy of Sciences of the United States of America. 111: 2040-5. PMID 24449901 DOI: 10.1073/pnas.1323618111  1
2013 Tsutsui K, Haraguchi S, Inoue K, Miyabara H, Ubuka T, Hatori M, Hirota T, Fukada Y. New biosynthesis and biological actions of avian neurosteroids. Journal of Experimental Neuroscience. 7: 15-29. PMID 25157204 DOI: 10.4137/JEN.S11148  1
2013 Tsutsui K, Haraguchi S, Hatori M, Hirota T, Fukada Y. Biosynthesis and biological actions of pineal neurosteroids in domestic birds. Neuroendocrinology. 98: 97-105. PMID 23797037 DOI: 10.1159/000353782  1
2013 Weger M, Weger BD, Diotel N, Rastegar S, Hirota T, Kay SA, Strähle U, Dickmeis T. Real-time in vivo monitoring of circadian E-box enhancer activity: a robust and sensitive zebrafish reporter line for developmental, chemical and neural biology of the circadian clock. Developmental Biology. 380: 259-73. PMID 23665472 DOI: 10.1016/j.ydbio.2013.04.035  1
2012 Hirota T, Lee JW, St John PC, Sawa M, Iwaisako K, Noguchi T, Pongsawakul PY, Sonntag T, Welsh DK, Brenner DA, Doyle FJ, Schultz PG, Kay SA. Identification of small molecule activators of cryptochrome. Science (New York, N.Y.). 337: 1094-7. PMID 22798407 DOI: 10.1126/science.1223710  1
2011 Lee JW, Hirota T, Peters EC, Garcia M, Gonzalez R, Cho CY, Wu X, Schultz PG, Kay SA. A small molecule modulates circadian rhythms through phosphorylation of the period protein. Angewandte Chemie (International Ed. in English). 50: 10608-11. PMID 21954091 DOI: 10.1002/anie.201103915  1
2011 Iyengar PV, Hirota T, Hirose S, Nakamura N. Membrane-associated RING-CH 10 (MARCH10 protein) is a microtubule-associated E3 ubiquitin ligase of the spermatid flagella. The Journal of Biological Chemistry. 286: 39082-90. PMID 21937444 DOI: 10.1074/jbc.M111.256875  1
2011 Hatori M, Hirota T, Iitsuka M, Kurabayashi N, Haraguchi S, Kokame K, Sato R, Nakai A, Miyata T, Tsutsui K, Fukada Y. Light-dependent and circadian clock-regulated activation of sterol regulatory element-binding protein, X-box-binding protein 1, and heat shock factor pathways. Proceedings of the National Academy of Sciences of the United States of America. 108: 4864-9. PMID 21383147 DOI: 10.1073/pnas.1015959108  1
2010 Hirota T, Lee JW, Lewis WG, Zhang EE, Breton G, Liu X, Garcia M, Peters EC, Etchegaray JP, Traver D, Schultz PG, Kay SA. High-throughput chemical screen identifies a novel potent modulator of cellular circadian rhythms and reveals CKIα as a clock regulatory kinase. Plos Biology. 8: e1000559. PMID 21179498 DOI: 10.1371/journal.pbio.1000559  1
2010 Zhang EE, Liu Y, Dentin R, Pongsawakul PY, Liu AC, Hirota T, Nusinow DA, Sun X, Landais S, Kodama Y, Brenner DA, Montminy M, Kay SA. Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis. Nature Medicine. 16: 1152-6. PMID 20852621 DOI: 10.1038/nm.2214  1
2010 Kurabayashi N, Hirota T, Sakai M, Sanada K, Fukada Y. DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping. Molecular and Cellular Biology. 30: 1757-68. PMID 20123978 DOI: 10.1128/MCB.01047-09  1
2010 Hirota T, Kon N, Itagaki T, Hoshina N, Okano T, Fukada Y. Transcriptional repressor TIEG1 regulates Bmal1 gene through GC box and controls circadian clockwork. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 15: 111-21. PMID 20070857 DOI: 10.1111/j.1365-2443.2009.01371.x  1
2009 Hirota T, Kay SA. High-throughput screening and chemical biology: new approaches for understanding circadian clock mechanisms. Chemistry & Biology. 16: 921-7. PMID 19778719 DOI: 10.1016/j.chembiol.2009.09.002  1
2009 Zhang EE, Liu AC, Hirota T, Miraglia LJ, Welch G, Pongsawakul PY, Liu X, Atwood A, Huss JW, Janes J, Su AI, Hogenesch JB, Kay SA. A genome-wide RNAi screen for modifiers of the circadian clock in human cells. Cell. 139: 199-210. PMID 19765810 DOI: 10.1016/j.cell.2009.08.031  1
2008 Hirota T, Lewis WG, Liu AC, Lee JW, Schultz PG, Kay SA. A chemical biology approach reveals period shortening of the mammalian circadian clock by specific inhibition of GSK-3beta. Proceedings of the National Academy of Sciences of the United States of America. 105: 20746-51. PMID 19104043 DOI: 10.1073/pnas.0811410106  1
2008 Kon N, Hirota T, Kawamoto T, Kato Y, Tsubota T, Fukada Y. Activation of TGF-beta/activin signalling resets the circadian clock through rapid induction of Dec1 transcripts. Nature Cell Biology. 10: 1463-9. PMID 19029909 DOI: 10.1038/ncb1806  1
2007 Tsuji T, Hirota T, Takemori N, Komori N, Yoshitane H, Fukuda M, Matsumoto H, Fukada Y. Circadian proteomics of the mouse retina. Proteomics. 7: 3500-8. PMID 17726681 DOI: 10.1002/pmic.200700272  1
2006 Kurabayashi N, Hirota T, Harada Y, Sakai M, Fukada Y. Phosphorylation of mCRY2 at Ser557 in the hypothalamic suprachiasmatic nucleus of the mouse. Chronobiology International. 23: 129-34. PMID 16687286 DOI: 10.1080/07420520500464478  1
2005 Harada Y, Sakai M, Kurabayashi N, Hirota T, Fukada Y. Ser-557-phosphorylated mCRY2 is degraded upon synergistic phosphorylation by glycogen synthase kinase-3 beta. The Journal of Biological Chemistry. 280: 31714-21. PMID 15980066 DOI: 10.1074/jbc.M506225200  1
2004 Hirota T, Fukada Y. Resetting mechanism of central and peripheral circadian clocks in mammals. Zoological Science. 21: 359-68. PMID 15118222 DOI: 10.2108/zsj.21.359  1
2003 Hayashi Y, Sanada K, Hirota T, Shimizu F, Fukada Y. p38 mitogen-activated protein kinase regulates oscillation of chick pineal circadian clock. The Journal of Biological Chemistry. 278: 25166-71. PMID 12719413 DOI: 10.1074/jbc.M212726200  1
2002 Hirota T, Okano T, Kokame K, Shirotani-Ikejima H, Miyata T, Fukada Y. Glucose down-regulates Per1 and Per2 mRNA levels and induces circadian gene expression in cultured Rat-1 fibroblasts. The Journal of Biological Chemistry. 277: 44244-51. PMID 12213820 DOI: 10.1074/jbc.M206233200  1
2001 Okano T, Yamamoto K, Okano K, Hirota T, Kasahara T, Sasaki M, Takanaka Y, Fukada Y. Chicken pineal clock genes: Implication of BMAL2 as a bidirectional regulator in circadian clock oscillation Genes to Cells. 6: 825-836. PMID 11554928 DOI: 10.1046/j.1365-2443.2001.00462.x  1
2001 Hirota T, Kagiwada S, Kasahara T, Okano T, Murata M, Fukada Y. Effect of brefeldin A on melatonin secretion of chick pineal cells Journal of Biochemistry. 129: 51-59. PMID 11134957  1
Low-probability matches
2017 Hatori M, Gronfier C, Van Gelder RN, Bernstein PS, Carreras J, Panda S, Marks F, Sliney D, Hunt CE, Hirota T, Furukawa T, Tsubota K. Global rise of potential health hazards caused by blue light-induced circadian disruption in modern aging societies. Npj Aging and Mechanisms of Disease. 3: 9. PMID 28649427 DOI: 10.1038/s41514-017-0010-2  0.16
2019 Kolarski D, Sugiyama A, Breton G, Rakers C, Ono D, Schulte A, Tama F, Itami K, Szymanski W, Hirota T, Feringa BL. Controlling the Circadian Clock with High Temporal Resolution through Photodosing. Journal of the American Chemical Society. PMID 31509406 DOI: 10.1021/jacs.9b05445  0.08
2014 Matsumoto N, Hirota T, Sugiyama K, Kim KT, Kim M, Byun DY, Jung T, Chibueze JO, Honma M, Kameya O, Kim J, Lyo AR, Motogi K, Oh C, Shino N, et al. The first very long baseline interferometry image of a 44 GHZ methanol maser with the KVN and VERA array (KaVA) Astrophysical Journal Letters. 789. DOI: 10.1088/2041-8205/789/1/L1  0.04
2013 Abe S, Hirota T, Kiba T, Miyakawa N, Watari F, Murayama A, Sato SI. Photophysical properties of self-assembled cyanine-dye dimmer formation assisted by cyclodextrin inclusion complexation Molecular Crystals and Liquid Crystals. 579: 22-29. DOI: 10.1080/15421406.2013.804799  0.04
2013 Kiba T, Hirota T, Murayama A, Sato SI. Structure and intermolecular dynamics of carbon disulfide/alcohols binary solution Molecular Crystals and Liquid Crystals. 579: 103-109. DOI: 10.1080/15421406.2013.802966  0.04
2019 Zhang Y, Hirota T, Kuwata K, Oishi S, Gramani SG, Bode JW. Chemical Synthesis of Atomically Tailored SUMO E2 Conjugating Enzymes for the Formation of Covalently Linked SUMO-E2-E3 Ligase Ternary Complexes. Journal of the American Chemical Society. PMID 31436980 DOI: 10.1021/jacs.9b06820  0.01
2017 Srivastava A, Hirota T, Irle S, Tama F. Conformational dynamics of human Protein Kinase CK2α and its effect on function and inhibition. Proteins. PMID 29243286 DOI: 10.1002/prot.25444  0.01
2017 Srivastava A, Hirota T, Irle S, Tama F. Conformational dynamics of human Protein Kinase CK2α and its effect on function and inhibition. Proteins. PMID 29243286 DOI: 10.1002/prot.25444  0.01
2017 Srivastava A, Hirota T, Irle S, Tama F. Conformational dynamics of human Protein Kinase CK2α and its effect on function and inhibition. Proteins. PMID 29243286 DOI: 10.1002/prot.25444  0.01
2016 Burkhardt S, Borsos M, Szydlowska A, Godwin J, Williams SA, Cohen PE, Hirota T, Saitou M, Tachibana-Konwalski K. Chromosome Cohesion Established by Rec8-Cohesin in Fetal Oocytes Is Maintained without Detectable Turnover in Oocytes Arrested for Months in Mice. Current Biology : Cb. PMID 26898469 DOI: 10.1016/j.cub.2015.12.073  0.01
2016 Liu T, Zhang Q, Kim KT, Wu Y, Lee CW, Lee JE, Tatematsu K, Choi M, Juvela M, Thompson M, Goldsmith PF, Liu SY, Naomi H, Koch P, Henkel C, ... ... Hirota T, et al. PLANCK COLD CLUMPS in the λ ORIONIS COMPLEX. I. DISCOVERY of AN EXTREMELY YOUNG CLASS 0 PROTOSTELLAR OBJECT and A PROTO-BROWN DWARF CANDIDATE in the BRIGHT-RIMMED CLUMP PGCC G192.32-11.88 Astrophysical Journal, Supplement Series. 222. DOI: 10.3847/0067-0049/222/1/7  0.01
2016 Hirota T, Kim MK, Honma M. Alma observation of the 658 GHz vibrationally excited H2O maser in Orion KL source i Astrophysical Journal. 817. DOI: 10.3847/0004-637X/817/2/168  0.01
2016 Uchida R, Okamoto H, Ikuta N, Terao K, Hirota T. Investigation of enantioselective membrane permeability of α-lipoic acid in Caco-2 and MDCKII cell International Journal of Molecular Sciences. 17. DOI: 10.3390/ijms17020155  0.01
2016 Hirota T, Tanaka M, Murakami T, Hiramitsu A, Sato H, Sato T. Effect of floor end and supporting leg position of floating floor of wood frame constluction floor on heavy-weight floor impact sound pressure level Journal of Environmental Engineering (Japan). 81: 41-48. DOI: 10.3130/aije.81.41  0.01
2016 Yamada H, Masuko H, Yatagai Y, Sakamoto T, Kaneko Y, Iijima H, Naito T, Noguchi E, Konno S, Nishimura M, Hirota T, Tamari M, Hizawa N. Role of lung function genes in the development of asthma Plos One. 11. DOI: 10.1371/journal.pone.0145832  0.01
2016 Burns RA, Handa T, Hirota T, Motogi K, Imai H, Omodaka T. Molecular jet emission and a spectroscopic survey of S235AB Astronomy and Astrophysics. 586. DOI: 10.1051/0004-6361/201527233  0.01
2016 Abe Y, Sako K, Takagaki K, Hirayama Y, Uchida KSK, Herman JA, DeLuca JG, Hirota T. HP1-Assisted Aurora B Kinase Activity Prevents Chromosome Segregation Errors Developmental Cell. 36: 487-497. DOI: 10.1016/j.devcel.2016.02.008  0.01
2016 Hirota T, Tamari M. GWAS for allergic diseases Japanese Journal of Allergology. 65: 25-31.  0.01
2015 Zhang B, Shimada Y, Hirota T, Ariyoshi M, Kuroyanagi J, Nishimura Y, Tanaka T. Novel immunologic tolerance of human cancer cell xenotransplants in zebrafish. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 26746804 DOI: 10.1016/j.trsl.2015.12.007  0.01
2015 Miki H, Tsuboi H, Kaneko S, Takahashi H, Yokosawa M, Asashima H, Hirota T, Hagiwara S, Umeda N, Kondo Y, Nishimura B, Sugano M, Matsumoto I, Sumida T. A case of refractory Kimura disease with a buccal bulky mass successfully treated with low-dose cyclosporine A: Report and review of the literature. Allergology International : Official Journal of the Japanese Society of Allergology. PMID 26666475 DOI: 10.1016/j.alit.2015.10.008  0.01
2015 Miyajima A, Kigure A, Anata T, Hirota T. Mechanism for transport of ivermectin to the stratum corneum in rats. Drug Metabolism and Pharmacokinetics. PMID 26613804 DOI: 10.1016/j.dmpk.2015.07.004  0.01
2015 Yamashiro C, Hirota T, Kurimoto K, Nakamura T, Yabuta Y, Nagaoka S, Ohta H, Yamamoto T, Saitou M. Persistent Requirement and Alteration of the Key Targets of PRDM1 During Primordial Germ Cell Development in Mice. Biology of Reproduction. PMID 26586842 DOI: 10.1095/biolreprod.115.133256  0.01
2015 Hirota T, Tamari M. GENETIC FACTORS OF ALLERGIC DISEASES IN THE JAPANESE POPULATION. Arerugī = [Allergy]. 64: 933-41. PMID 26464367 DOI: 10.15036/arerugi.64.933  0.01
2015 Uchida R, Okamoto H, Ikuta N, Terao K, Hirota T. Enantioselective Pharmacokinetics of α-Lipoic Acid in Rats. International Journal of Molecular Sciences. 16: 22781-94. PMID 26402669 DOI: 10.3390/ijms160922781  0.01
2015 Takahashi H, Tsuboi H, Abe S, Yokosawa M, Hagiwara S, Asashima H, Hirota T, Umeda N, Kondo Y, Matsumoto I, Sumida T. Magnetic resonance imaging can reveal fascial vasculitis in a patient with microscopic polyangiitis. Scandinavian Journal of Rheumatology. 1-2. PMID 26399877 DOI: 10.3109/03009742.2015.1085084  0.01
2015 Kishi T, Hirota T, Matsunaga S, Iwata N. Antipsychotic medications for the treatment of delirium: a systematic review and meta-analysis of randomised controlled trials. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 26341326 DOI: 10.1136/jnnp-2015-311049  0.01
2015 So R, Hirota T, Yamamoto Y, Hishimoto A, Correll CU. Lack of cardinal symptoms of meningitis in a hospitalized patient with chronic schizophrenia: lessons to be learned. General Hospital Psychiatry. PMID 26324862 DOI: 10.1016/j.genhosppsych.2015.07.011  0.01
2015 Kubo T, Okumiya T, Baba Y, Hirota T, Tanioka K, Yamasaki N, Sugiura T, Doi YL, Kitaoka H. Erythrocyte creatine as a marker of intravascular hemolysis due to left ventricular outflow tract obstruction in hypertrophic cardiomyopathy. Journal of Cardiology. PMID 26254020 DOI: 10.1016/j.jjcc.2015.05.005  0.01
2015 Benza RL, Gomberg-Maitland M, Demarco T, Frost AE, Torbicki A, Langleben D, Pulido T, Correa-Jaque P, Passineau MJ, Wiener HW, Tamari M, Hirota T, Kubo M, Tiwari HK. ET-1 Pathway Polymorphisms Affect Outcome in Pulmonary Arterial Hypertension. American Journal of Respiratory and Critical Care Medicine. PMID 26252367 DOI: 10.1164/rccm.201501-0196OC  0.01
2015 Hirota T, Suzuki T, Ogishima H, Hagiwara S, Ebe H, Takahashi H, Yokosawa M, Umeda N, Kondo Y, Tsuboi H, Matsumoto I, Sumida T. Evaluation of changes in magnetic resonance images following 24 and 52 weeks treatment of rheumatoid arthritis with infliximab, tocilizumab or abatacept. Modern Rheumatology / the Japan Rheumatism Association. 1-19. PMID 26140463 DOI: 10.3109/14397595.2015.1069471  0.01
2015 Hirota T, Hirota K. [Bone and Nutrition. Nutritional management of osteoporosis]. Clinical Calcium. 25: 1049-55. PMID 26119319  0.01
2015 Kubo T, Baba Y, Hirota T, Tanioka K, Yamasaki N, Yamanaka S, Iiyama T, Kumagai N, Furuno T, Sugiura T, Kitaoka H. Differentiation of infiltrative cardiomyopathy from hypertrophic cardiomyopathy using high-sensitivity cardiac troponin T: a case-control study. Bmc Cardiovascular Disorders. 15: 53. PMID 26077897 DOI: 10.1186/s12872-015-0043-z  0.01
2015 Hirota T, Ieiri I. Drug-drug interactions that interfere with statin metabolism. Expert Opinion On Drug Metabolism & Toxicology. 11: 1435-47. PMID 26058399 DOI: 10.1517/17425255.2015.1056149  0.01
2015 Minamino M, Ishibashi M, Nakato R, Akiyama K, Tanaka H, Kato Y, Negishi L, Hirota T, Sutani T, Bando M, Shirahige K. Esco1 Acetylates Cohesin via a Mechanism Different from That of Esco2. Current Biology : Cb. PMID 26051894 DOI: 10.1016/j.cub.2015.05.017  0.01
2015 Nagasaka K, Hirota T. Clarifying the role of condensin in shaping chromosomes. Nature Cell Biology. 17: 711-3. PMID 26022918 DOI: 10.1038/ncb3183  0.01
2015 Sugiyama I, Bouillon T, Yamaguchi M, Suzuki H, Hirota T, Fink M. Population pharmacokinetic analysis for 10-monohydroxy derivative of oxcarbazepine in pediatric epileptic patients shows no difference between Japanese and other ethnicities. Drug Metabolism and Pharmacokinetics. 30: 160-7. PMID 25989891 DOI: 10.1016/j.dmpk.2014.12.002  0.01
2015 Kurata I, Tsuboi H, Takahashi H, Yagishita M, Abe S, Ebe H, Takahashi H, Asashima H, Hirota T, Hagiwara S, Umeda N, Kondo Y, Ogishima H, Suzuki T, Matsumoto I, et al. A case of relapsing neurosarcoidosis with brain nodules and hydrocephalus successfully treated by corticosteroid and methotrexate. Rheumatology (Oxford, England). 54: 1160. PMID 25957441 DOI: 10.1093/rheumatology/kev109  0.01
2015 Uchida R, Iwamoto K, Nagayama S, Miyajima A, Okamoto H, Ikuta N, Fukumi H, Terao K, Hirota T. Effect of γ-Cyclodextrin Inclusion Complex on the Absorption of R-α-Lipoic Acid in Rats. International Journal of Molecular Sciences. 16: 10105-20. PMID 25946345 DOI: 10.3390/ijms160510105  0.01
2015 Kim KW, Myers RA, Lee JH, Igartua C, Lee KE, Kim YH, Kim EJ, Yoon D, Lee JS, Hirota T, Tamari M, Takahashi A, Kubo M, Choi JM, Kim KE, et al. Genome-wide association study of recalcitrant atopic dermatitis in Korean children. The Journal of Allergy and Clinical Immunology. PMID 25935106 DOI: 10.1016/j.jaci.2015.03.030  0.01
2015 Sakashita M, Yamada T, Imoto Y, Hirota T, Tamari M, Ito Y, Kubo S, Osawa Y, Takahashi N, Fujieda S. Long-term sublingual immunotherapy for Japanese cedar pollinosis and the levels of IL-17A and complement components 3a and 5a. Cytokine. PMID 25934649 DOI: 10.1016/j.cyto.2015.03.019  0.01
2015 Baba Y, Kubo T, Yamanaka S, Hirota T, Tanioka K, Yamasaki N, Sugiura T, Kitaoka H. Clinical significance of high-sensitivity cardiac troponin T in patients with dilated cardiomyopathy. International Heart Journal. 56: 309-13. PMID 25912901 DOI: 10.1536/ihj.14-335  0.01
2015 Asashima H, Tsuboi H, Takahashi H, Hirota T, Iizuka M, Kondo Y, Matsui M, Matsumoto I, Sumida T. The anergy induction of M3 muscarinic acetylcholine receptor reactive CD4+ T cell suppresses experimental sialadenitis like Sjögren's syndrome. Arthritis & Rheumatology (Hoboken, N.J.). PMID 25891013 DOI: 10.1002/art.39163  0.01
2015 Miyajima A, Yamamoto Y, Hirota T. Effect of high fat intake on the pharmacokinetic profile of ivermectin in rabbits. Drug Metabolism and Pharmacokinetics. 30: 253-6. PMID 25887422 DOI: 10.1016/j.dmpk.2015.02.002  0.01
2015 Gotanda K, Tokumoto T, Hirota T, Fukae M, Ieiri I. Sulfasalazine disposition in a subject with 376C>T (nonsense mutation) and 421C>A variants in the ABCG2 gene. British Journal of Clinical Pharmacology. PMID 25872459 DOI: 10.1111/bcp.12654  0.01
2015 Takahashi H, Tsuboi H, Ogishima H, Yokosawa M, Takahashi H, Yagishita M, Abe S, Hagiwara S, Asashima H, Hirota T, Umeda N, Kondo Y, Suzuki T, Matsumoto I, Sumida T. [18F]fluorodeoxyglucose positron emission tomography/computed tomography can reveal subclinical prostatitis in a patient with IgG4-related disease. Rheumatology (Oxford, England). 54: 1113. PMID 25863043 DOI: 10.1093/rheumatology/kev099  0.01
2015 Tanaka S, Tamari M, Nakayama T, Ishii H, Hatsushika K, Hayashi A, Watanabe H, Kanai M, Osano M, Yonaga T, Tomita K, Fujieda S, Sakuma Y, Shiono O, Ishitoya J, ... ... Hirota T, et al. Synergistic suppression of Poly(I:C)-induced CCL3 by a corticosteroid and a long acting β2 agonist in nasal epithelial cells. Allergology International : Official Journal of the Japanese Society of Allergology. 64: 196-9. PMID 25838100 DOI: 10.1016/j.alit.2014.10.006  0.01
2015 Miyajima A, Bamba M, Muto T, Hirota T. Dysfunction of blood pressure regulation in hyperhomocyteinemia model in rats. The Journal of Toxicological Sciences. 40: 211-21. PMID 25786525 DOI: 10.2131/jts.40.211  0.01
2015 Fujieda S, Sakashita M, Tokunaga T, Okano M, Haruna T, Yoshikawa M, Ohtori N, Asaka D, Haruna S, Nakayama T, Ishitoya J, Sakuma Y, Hirakawa K, Takeno S, Himi T, ... ... Hirota T, et al. [Eosinophilic chronic rhinosinusitis]. Arerugī = [Allergy]. 64: 38-45. PMID 25779061  0.01
2015 Yamada H, Yatagai Y, Masuko H, Sakamoto T, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Hizawa N. Heritability of pulmonary function estimated from genome-wide SNPs in healthy Japanese adults. Respiratory Investigation. 53: 60-7. PMID 25745850 DOI: 10.1016/j.resinv.2014.10.004  0.01
2015 Miyajima A, Komoda M, Akagi K, Yuzawa K, Yoshimasu T, Yamamoto Y, Hirota T. Experimental study of pharmacokinetics of external, whole-body bathing application of ivermectin. The Journal of Dermatology. 42: 87-9. PMID 25492083 DOI: 10.1111/1346-8138.12728  0.01
2015 Iizuka M, Tsuboi H, Matsuo N, Asashima H, Hirota T, Kondo Y, Iwakura Y, Takahashi S, Matsumoto I, Sumida T. A crucial role of RORγt in the development of spontaneous Sialadenitis-like Sjögren's syndrome. Journal of Immunology (Baltimore, Md. : 1950). 194: 56-67. PMID 25411202 DOI: 10.4049/jimmunol.1401118  0.01
2015 Takahashi H, Tsuboi H, Kurata I, Takahashi H, Inoue S, Ebe H, Yokosawa M, Hagiwara S, Hirota T, Asashima H, Kaneko S, Kawaguchi H, Kurashima Y, Miki H, Umeda N, et al. Predictors of the response to treatment in acute lupus hemophagocytic syndrome. Lupus. 24: 659-68. PMID 25391543 DOI: 10.1177/0961203314559086  0.01
2015 Hirota T, Guerrero A, Sartorius N, Fung D, Leventhal B, Ong SH, Kaneko H, Kim B, Cho SC, Skokauskas N. Child and adolescent psychiatry in the Far East. Psychiatry and Clinical Neurosciences. 69: 171-7. PMID 25346228 DOI: 10.1111/pcn.12248  0.01
2015 Yokosawa M, Tsuboi H, Nasu K, Hagiya C, Hagiwara S, Hirota T, Ebe H, Takahashi H, Asashima H, Kondo Y, Ogishima H, Suzuki T, Minami M, Bukawa H, Matsumoto I, et al. Usefulness of MR imaging of the parotid glands in patients with secondary Sjögren's syndrome associated with rheumatoid arthritis. Modern Rheumatology / the Japan Rheumatism Association. 25: 415-20. PMID 25295917 DOI: 10.3109/14397595.2014.958892  0.01
2015 Suzuki T, Hirota T, Ogishima H, Umeda N, Kondo Y, Yokosawa M, Miki H, Tsuboi H, Matsumoto I, Sumida T. Subclinical inflammation with tocilizumab treatment of rheumatoid arthritis: MRI evaluation for 2 years. International Journal of Rheumatic Diseases. 18: 108-10. PMID 25294091 DOI: 10.1111/1756-185X.12460  0.01
2015 Hirota T, Yoshida Y, Kitasato Y, Yoshimi M, Koga T, Tsuruta N, Minami M, Harada T, Ishii H, Fujita M, Nabeshima K, Nagata N, Watanabe K. Histological evolution of pleuroparenchymal fibroelastosis. Histopathology. 66: 545-54. PMID 25234959 DOI: 10.1111/his.12554  0.01
2015 Tsuboi H, Matsumoto I, Hagiwara S, Hirota T, Takahashi H, Ebe H, Yokosawa M, Hagiya C, Asashima H, Takai C, Miki H, Umeda N, Kondo Y, Ogishima H, Suzuki T, et al. Efficacy and safety of abatacept for patients with Sjögren's syndrome associated with rheumatoid arthritis: rheumatoid arthritis with orencia trial toward Sjögren's syndrome Endocrinopathy (ROSE) trial-an open-label, one-year, prospective study-Interim analysis of 32 patients for 24 weeks. Modern Rheumatology / the Japan Rheumatism Association. 25: 187-93. PMID 25211401 DOI: 10.3109/14397595.2014.951144  0.01
2015 Terauchi Y, Kubo T, Baba Y, Hirota T, Tanioka K, Yamasaki N, Furuno T, Kitaoka H. Gender differences in the clinical features of hypertrophic cardiomyopathy caused by cardiac myosin-binding protein C gene mutations. Journal of Cardiology. 65: 423-8. PMID 25123604 DOI: 10.1016/j.jjcc.2014.07.010  0.01
2015 Ebe H, Tsuboi H, Hagiya C, Takahashi H, Yokosawa M, Hagiwara S, Hirota T, Kurashima Y, Takai C, Miki H, Asashima H, Umeda N, Kondo Y, Ogishima H, Suzuki T, et al. Clinical features of patients with IgG4-related disease complicated with perivascular lesions. Modern Rheumatology / the Japan Rheumatism Association. 25: 105-9. PMID 24754274 DOI: 10.3109/14397595.2014.903596  0.01
2015 Iizuka M, Tsuboi H, Asashima H, Hirota T, Kondo Y, Matsui M, Matsumoto I, Sumida T. M3 muscarinic acetylcholine receptor reactive IL-17 producing T cells promotes development of Sjögren's syndrome like sialadenitis. Modern Rheumatology / the Japan Rheumatism Association. 25: 158-60. PMID 24593169 DOI: 10.3109/14397595.2014.884683  0.01
2015 Uchida R, Iwamoto K, Nagayama S, Miyajima A, Okamoto H, Ikuta N, Fukumi H, Terao K, Hirota T. Effect of γ-cyclodextrin inclusion complex on the absorption of R-α-lipoic acid in rats International Journal of Molecular Sciences. 16: 10105-10120. DOI: 10.3390/ijms160510105  0.01
2015 Sugiyama I, Murayama N, Kuroki A, Kota J, Iwano S, Yamazaki H, Hirota T. Evaluation of cytochrome P450 inductions by anti-epileptic drug oxcarbazepine, 10-hydroxyoxcarbazepine, and carbamazepine using human hepatocytes and HepaRG cells Xenobiotica. 1-10. DOI: 10.3109/00498254.2015.1118774  0.01
2015 Shimoda S, Yazaki T, Nishio Z, Hamasaki T, Hirota T. Possible soil frost control by snow compaction on winter wheat fields Journal of Agricultural Meteorology. 71: 276-281. DOI: 10.2480/agrmet.D-15-00001  0.01
2015 Ueeda Y, Taniguchi K, Inami S, Kaneko G, Hirota T, Yang WH, Kamiya Y, Daisho Y. Performance degradation prediction and cell balance control algorithm construction of lithium iron phosphate battery 2014 Ieee Vehicle Power and Propulsion Conference, Vppc 2014. DOI: 10.1109/VPPC.2014.7007118  0.01
2015 Iwakata S, Hayashi H, Kotaka M, Makino S, Moroya T, Noguchi K, Hirota T, Itoh K. Dual band characteristics of a linear antenna over a capacitance-grid-type AMC substrate Isap 2014 - 2014 International Symposium On Antennas and Propagation, Conference Proceedings. 369-370. DOI: 10.1109/ISANP.2014.7026684  0.01
2015 Fujii Y, Ikarashi K, Makino S, Hirota T, Noguchi K, Itoh K. High-efficiency and low-side-lobe reflectarray antenna Isap 2014 - 2014 International Symposium On Antennas and Propagation, Conference Proceedings. 351-352. DOI: 10.1109/ISANP.2014.7026675  0.01
2015 Moroya T, Makino S, Hirota T, Noguchi K, Itoh K, Ikarashi K. Polarization conversion reflector using a metal-plate-loaded meander line Isap 2014 - 2014 International Symposium On Antennas and Propagation, Conference Proceedings. 171-172. DOI: 10.1109/ISANP.2014.7026585  0.01
2015 Moroya T, Kotaka M, Makino S, Hayashi H, Noguchi K, Hirota T, Itoh K. Proposal of a dipole antenna unified with an AMC substrate Ieee Antennas and Propagation Society, Ap-S International Symposium (Digest). 2015: 1408-1409. DOI: 10.1109/APS.2015.7305093  0.01
2015 Tanaka A, Noguchi K, Makino S, Hirota T, Itoh K. Evaluation of miniaturizing factor for folded inverted-L antennas Ieee Antennas and Propagation Society, Ap-S International Symposium (Digest). 2015: 1244-1245. DOI: 10.1109/APS.2015.7305011  0.01
2015 Watanabe Y, Sakai N, López-Sepulcre A, Furuya R, Sakai T, Hirota T, Liu SY, Su YN, Yamamoto S. Spectral line survey toward the young massive protostar ngc 2264 cmm3 in the 4 mm, 3 mm, and 0.8 mm bands Astrophysical Journal. 809. DOI: 10.1088/0004-637X/809/2/162  0.01
2015 Sakai Y, Kobayashi K, Hirota T. An ALMA imaging study of methyl formate (HCOOCH3) in torsionally excited states Toward Orion KL Astrophysical Journal. 803. DOI: 10.1088/0004-637X/803/2/97  0.01
2015 Sakai T, Sakai N, Furuya K, Aikawa Y, Hirota T, Foster JB, Sanhueza P, Jackson JM, Yamamoto S. ALMA observations of the IRDC CLUMP G34.43+00.24 MM3: DNC/HNC ratio Astrophysical Journal. 803. DOI: 10.1088/0004-637X/803/2/70  0.01
2015 Hirota T, Kim MK, Kurono Y, Honma M. ALMA imaging of millimeter/submillimeter continuum emission in orion KL Astrophysical Journal. 801. DOI: 10.1088/0004-637X/801/2/82  0.01
2015 Ohkubo S, Nagata O, Hirota T. Estimating NEE in a wheat-planted plot with an automatically controlled chamber Soil Science and Plant Nutrition. 61: 76-87. DOI: 10.1080/00380768.2014.920243  0.01
2015 Matsumoto A, Tamura A, Honda T, Hirota T, Kobayashi K, Katakura S, Nishi N, Amano KI, Fukami K, Sakka T. Transfer of the Species Dissolved in a Liquid into Laser Ablation Plasma: An Approach Using Emission Spectroscopy Journal of Physical Chemistry C. 119: 26506-26511. DOI: 10.1021/acs.jpcc.5b07769  0.01
2015 Yoshida Y, Nagata N, Tsuruta N, Kitasato Y, Wakamatsu K, Yoshimi M, Ishii H, Hirota T, Hamada N, Fujita M, Nabeshima K, Kiyomi F, Watanabe K. Heterogeneous clinical features in patients with pulmonary fibrosis showing histology of pleuroparenchymal fibroelastosis Respiratory Investigation. DOI: 10.1016/j.resinv.2015.11.002  0.01
2015 Ishida Y, Hirota T, Sato S, Kamegai M, Kim SK, Park SY, Koo DH, Shon MS, Kim GN, Park HR, Lee SC. Discriminative analysis of free and esterified gallic acids in acorn shells by thermochemolysis-gas chromatography/mass spectrometry in the presence of organic alkalis Journal of Analytical and Applied Pyrolysis. DOI: 10.1016/j.jaap.2015.09.019  0.01
2015 Sugiyama I, Bouillon T, Yamaguchi M, Suzuki H, Hirota T, Fink M. Population pharmacokinetic analysis for 10-monohydroxy derivative of oxcarbazepine in pediatric epileptic patients shows no difference between Japanese and other ethnicities Drug Metabolism and Pharmacokinetics. 30: 160-167. DOI: 10.1016/j.dmpk.2014.12.002  0.01
2015 Suda Y, Nagatomo M, Yokoyama R, Ohzono M, Aoyama K, Zhang X, Nakajima K, Murakami N, Shinoda T, Hirota T, Yanagihara S, Nishi JI. Highly sensitive detection of influenza virus in saliva by real-time PCR method using sugar chain-immobilized gold nanoparticles; application to clinical studies Biotechnology Reports. 7: 64-71. DOI: 10.1016/j.btre.2015.05.004  0.01
2015 Shimoda S, Hamasaki T, Hirota T, Kanno H, Nishio Z. Sensitivity of wheat yield to temperature changes with regional sunlight characteristics in eastern Hokkaido International Journal of Climatology. 35: 4176-4185. DOI: 10.1002/joc.4276  0.01
2015 Okuda K, Takarada S, Hirota T, Sasaki K. Polycyclic N-heterocyclic compounds. Part 86: Synthesis and evaluation of antiplatelet aggregation activity of 2,4-disubstituted 9-chloro-5,6-dihydropyrimido[5,4-d]benzazepine and related compounds Journal of Heterocyclic Chemistry. 52: 780-792. DOI: 10.1002/jhet.2190  0.01
2015 Okuda K, Zhang YX, Hirota T, Sasaki K. Polycyclic N-heterocyclic compounds. Part 85: Synthesis and evaluation of antiplatelet aggregation activity of 2,4-disubstituted 5,6-dihydro[1]benzazepino[5,4-d]pyrimidine and related compounds Journal of Heterocyclic Chemistry. 52: 888-895. DOI: 10.1002/jhet.2040  0.01
2015 Okuda K, Ide R, Uramaru N, Hirota T. Polycyclic N-heterocyclic compounds. Part 84: Reaction of N-(pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-yl)amidines or N-(pyrido[2',3':4,5]furo[3,2-d]pyrimidin-4-yl)amidines with hydroxylamine hydrochloride Journal of Heterocyclic Chemistry. 52: 880-887. DOI: 10.1002/jhet.2033  0.01
2015 Okuda K, Itzuji Y, Hirota T. Polycyclic N-heterocyclic compounds. Part 81: Synthesis and evaluation of pentacyclic 1,2,4,5-tetrahydro[1]benzothieno[2′,3′:6,7]thiepino[4,5-e]imidazo[1,2-c]pyrimidine and related compounds as potential antiplatelet aggregators Journal of Heterocyclic Chemistry. 51: 1528-1530. DOI: 10.1002/jhet.1754  0.01
2015 Mishima K, Siregar YDI, Kawamura H, Kawakami R, Ito S, Inoue Y, Hirota T, Harada T, Kato T, Misumi M, Suetsugu T, Irie K, Mustofa S, Hasanah F, Zaharo H, et al. Extraction of resveratrol from Melinjo (Gnetum gnemon L.) seeds using mixtures of liquid carbon dioxide and ethanol Solvent Extraction Research and Development. 22: 69-77.  0.01
2015 Hirota T, Tanaka M, Hiramitsu A, Sato T. Relationship between floor-impact sound and driving-point impedance of the surface material for wooden floor with floating floor system Journal of Environmental Engineering (Japan). 80: 501-508.  0.01
2015 Tatematsu K, Hirota T, Takakura M, Tsukidate T, Suzuki H, Hayama H. Thermal insulation and equipment performance of a newly built detached house in Hokkaido Journal of Environmental Engineering (Japan). 80: 67-77.  0.01
2015 Mishima K, Kawamura H, Kawakami R, Ito S, Inoue Y, Hirota T, Harada T, Kato T, Sharmin T, Misumi M, Suetsugu T, Irie K, Mustofa S, Hasanah F, Siregar YDI, et al. Extraction of apigenin and luteolin from leaves of alfalfa (Medicago sativa L.) using mixtures of liquid carbon dioxide and ethanol Solvent Extraction Research and Development. 22: 177-186.  0.01
2015 Mishima K, Kawamura H, Ito S, Inoue Y, Hirota T, Kato T, Sharmin T, Kawakami R, Irie K, Harada T, Mustofa S, Hasanah F, Siregar YDI, Putri LSE, Salim A. Liquid carbon dioxide extraction of xanthones from the pericarps of Garcinia Mangostana Linn. Enhanced by ultrasonic irradiation Solvent Extraction Research and Development. 22: 187-199.  0.01
2014 Mitoma C, Nakahara T, Uchi H, Ito T, Inatomi Y, Ide T, Jinnai S, Jinnai N, Iwasaki N, Sakamoto K, Kimura N, Maeda A, Kuma Y, Maehara E, Tsutsumi M, ... ... Hirota T, et al. Preferential expression of OVOL1 in inner root sheath of hair, sebaceous gland, eccrine duct and their neoplasms in human skin. Fukuoka Igaku Zasshi = Hukuoka Acta Medica. 105: 166-73. PMID 25509883  0.01
2014 Hayashi M, Nakayama T, Hirota T, Saeki H, Nobeyama Y, Ito T, Umezawa Y, Fukuchi O, Yanaba K, Kikuchi S, Nakagawa H, Tsunemi Y, Shibata S, Sato S, Tada Y, et al. Novel IL36RN gene mutation revealed by analysis of 8 Japanese patients with generalized pustular psoriasis. Journal of Dermatological Science. 76: 267-9. PMID 25468355 DOI: 10.1016/j.jdermsci.2014.10.008  0.01
2014 Yanagihara S, Goto H, Hirota T, Fukuda S, Ohno H, Yamamoto N. Lactobacillus acidophilus L-92 Cells Activate Expression of Immunomodulatory Genes in THP-1 Cells. Bioscience of Microbiota, Food and Health. 33: 157-64. PMID 25379363 DOI: 10.12938/bmfh.33.157  0.01
2014 Hagiwara S, Tsuboi H, Hagiya C, Yokosawa M, Hirota T, Ebe H, Takahashi H, Ogishima H, Asashima H, Kondo Y, Umeda N, Suzuki T, Hitomi S, Matsumoto I, Sumida T. Pulmonary nocardiosis in patients with connective tissue disease: A report of two cases. Intractable & Rare Diseases Research. 3: 25-8. PMID 25343123 DOI: 10.5582/irdr.3.25  0.01
2014 Okada H, Kusaka T, Fuke N, Kunikata J, Kondo S, Iwase T, Nan W, Hirota T, Ieiri I, Itoh S. Neonatal Dubin-Johnson syndrome: novel compound heterozygous mutation in the ABCC2 gene. Pediatrics International : Official Journal of the Japan Pediatric Society. 56: e62-4. PMID 25336012 DOI: 10.1111/ped.12404  0.01
2014 Kakuda T, Hirota T, Takeuchi T, Hagiuda H, Miyazaki S, Takai S. VirS, an OmpR/PhoB subfamily response regulator, is required for activation of vapA gene expression in Rhodococcus equi. Bmc Microbiology. 14: 243. PMID 25281192 DOI: 10.1186/s12866-014-0243-1  0.01
2014 Iizuka M, Wakasa Y, Tsuboi H, Asashima H, Hirota T, Kondo Y, Matsumoto I, Sumida T, Takaiwa F. Prophylactic effect of the oral administration of transgenic rice seeds containing altered peptide ligands of type II collagen on rheumatoid arthritis. Bioscience, Biotechnology, and Biochemistry. 78: 1662-8. PMID 25273131 DOI: 10.1080/09168451.2014.936349  0.01
2014 Yatagai Y, Sakamoto T, Yamada H, Masuko H, Kaneko Y, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Konno S, Nishimura M, Hizawa N. Genomewide association study identifies HAS2 as a novel susceptibility gene for adult asthma in a Japanese population. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 44: 1327-34. PMID 25251750 DOI: 10.1111/cea.12415  0.01
2014 Tamari M, Saeki H, Hayashi M, Umezawa Y, Ito T, Fukuchi O, Nobeyama Y, Yanaba K, Nakagawa H, Tsunemi Y, Kato T, Shibata S, Sugaya M, Sato S, Tada Y, ... ... Hirota T, et al. An association study of 36 psoriasis susceptibility loci for psoriasis vulgaris and atopic dermatitis in a Japanese population. Journal of Dermatological Science. 76: 156-7. PMID 25205357 DOI: 10.1016/j.jdermsci.2014.08.005  0.01
2014 Hirota T, Suzuki T, Hagiwara S, Ogishima H, Matsumoto I, Sumida T. Analysis of the usefulness of magnetic resonance imaging evaluation for rheumatoid arthritis treated with biological agents in the early phase: retrospective observation of abatacept and infliximab. Clinical and Experimental Rheumatology. 32: 991. PMID 25190645  0.01
2014 Sasaki T, Furusyo N, Shiohama A, Takeuchi S, Nakahara T, Uchi H, Hirota T, Tamari M, Shimizu N, Ebihara T, Amagai M, Furue M, Hayashi J, Kudoh J. Filaggrin loss-of-function mutations are not a predisposing factor for atopic dermatitis in an Ishigaki Island under subtropical climate. Journal of Dermatological Science. 76: 10-5. PMID 25086748 DOI: 10.1016/j.jdermsci.2014.06.004  0.01
2014 Hatakeyama D, Shoji M, Yamayoshi S, Hirota T, Nagae M, Yanagisawa S, Nakano M, Ohmi N, Noda T, Kawaoka Y, Kuzuhara T. A novel functional site in the PB2 subunit of influenza A virus essential for acetyl-CoA interaction, RNA polymerase activity, and viral replication. The Journal of Biological Chemistry. 289: 24980-94. PMID 25063805 DOI: 10.1074/jbc.M114.559708  0.01
2014 Kamei M, Miyajima A, Fujisawa M, Matsuoka Y, Hirota T. Effects of postnatal dexamethasone treatment on mRNA expression profiles of genes related to alveolar development in an emphysema model in mice. The Journal of Toxicological Sciences. 39: 665-70. PMID 25056791 DOI: DN/JST.JSTAGE/jts/39.665  0.01
2014 Niwa K, Oribe A, Okumura H, Shimono M, Nagai K, Hirota T, Yasue H, Kawase M. Tag/hybridization-based sensitive detection of polymerase chain reaction products. Analytical Biochemistry. 464: 12-6. PMID 25051253 DOI: 10.1016/j.ab.2014.07.010  0.01
2014 Yi S, An H, Lee H, Lee S, Ieiri I, Lee Y, Cho JY, Hirota T, Fukae M, Yoshida K, Nagatsuka S, Kimura M, Irie S, Sugiyama Y, Shin DW, et al. Korean, Japanese, and Chinese populations featured similar genes encoding drug-metabolizing enzymes and transporters: a DMET Plus microarray assessment. Pharmacogenetics and Genomics. 24: 477-85. PMID 25029633 DOI: 10.1097/FPC.0000000000000075  0.01
2014 Iizuka M, Wakasa Y, Tsuboi H, Asashima H, Hirota T, Kondo Y, Matsumoto I, Takaiwa F, Sumida T. Suppression of collagen-induced arthritis by oral administration of transgenic rice seeds expressing altered peptide ligands of type II collagen. Plant Biotechnology Journal. 12: 1143-52. PMID 24989432 DOI: 10.1111/pbi.12223  0.01
2014 Nishimura K, Ide R, Hirota T, Kawazu K, Kodama S, Takesue H, Ieiri I. Identification and functional characterization of novel nonsynonymous variants in the human multidrug and toxin extrusion 2-K. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 1432-7. PMID 24985703 DOI: 10.1124/dmd.114.056887  0.01
2014 Segawa S, Goto D, Horikoshi M, Kondo Y, Umeda N, Hagiwara S, Yokosawa M, Hirota T, Miki H, Tsuboi H, Ogishima H, Suzuki T, Matsumoto I, Sumida T. Involvement of CD161+ Vδ1+ γδ T cells in systemic sclerosis: association with interstitial pneumonia. Rheumatology (Oxford, England). 53: 2259-69. PMID 24972843 DOI: 10.1093/rheumatology/keu246  0.01
2014 Sakashita M, Makino Y, Noguchi E, Hirota T, Tamari M, Fujieda S. [Clinical relevance of biomarkers in allergic rhinitis]. ArerugÄ« = [Allergy]. 63: 767-74. PMID 24953736  0.01
2014 Tsuboi H, Nakai Y, Iizuka M, Asashima H, Hagiya C, Tsuzuki S, Hirota T, Miki H, Hagiwara S, Kondo Y, Tanaka A, Moriyama M, Matsumoto I, Nakamura S, Yoshihara T, et al. DNA microarray analysis of labial salivary glands in IgG4-related disease: comparison with Sjögren's syndrome. Arthritis & Rheumatology (Hoboken, N.J.). 66: 2892-9. PMID 24943710 DOI: 10.1002/art.38748  0.01
2014 Sumitomo H, Shiraishi K, Hirota T. Do males bite females' antennae to coerce copulation or to continue mate guarding in Oiceoptoma subrufum (Coleoptera: Silphinae)? Zoological Science. 31: 343-7. PMID 24882093 DOI: 10.2108/zs130255  0.01
2014 Harada T, Yoshida Y, Kitasato Y, Tsuruta N, Wakamatsu K, Hirota T, Tanaka M, Tashiro N, Ishii H, Shiraishi M, Fujita M, Nagata N, Watanabe K. The thoracic cage becomes flattened in the progression of pleuroparenchymal fibroelastosis. European Respiratory Review : An Official Journal of the European Respiratory Society. 23: 263-6. PMID 24881083 DOI: 10.1183/09059180.00006713  0.01
2014 Kakara M, Nomura H, Fukae M, Gotanda K, Hirota T, Matsubayashi S, Shimomura H, Hirakawa M, Ieiri I. Population pharmacodynamic analysis of LDL-cholesterol lowering effects by statins and co-medications based on electronic medical records. British Journal of Clinical Pharmacology. 78: 824-35. PMID 24734885 DOI: 10.1111/bcp.12405  0.01
2014 Nonaka A, Nakamura T, Hirota T, Matsushita A, Asakura M, Ohki K, Kitakaze M. The milk-derived peptides Val-Pro-Pro and Ile-Pro-Pro attenuate arterial dysfunction in L-NAME-treated rats. Hypertension Research : Official Journal of the Japanese Society of Hypertension. 37: 703-7. PMID 24694646 DOI: 10.1038/hr.2014.72  0.01
2014 Izuhara Y, Matsumoto H, Kanemitsu Y, Izuhara K, Tohda Y, Horiguchi T, Kita H, Kuwabara K, Tomii K, Otsuka K, Fujimura M, Ohkura N, Tomita K, Yokoyama A, Ohnishi H, ... ... Hirota T, et al. GLCCI1 variant accelerates pulmonary function decline in patients with asthma receiving inhaled corticosteroids. Allergy. 69: 668-73. PMID 24673601 DOI: 10.1111/all.12400  0.01
2014 Iijima H, Yamada H, Yatagai Y, Kaneko Y, Naito T, Sakamoto T, Masuko H, Hirota T, Tamari M, Konno S, Nishimura M, Hizawa N. [Effects of thymic stromal lymphopoietin (TSLP) genotypes on asthma phenotypes defined by the atopy cluster -influence of smoking habits-]. ArerugÄ« = [Allergy]. 63: 33-44. PMID 24647421  0.01
2014 Tamari M, Hirota T. Genome-wide association studies of atopic dermatitis. The Journal of Dermatology. 41: 213-20. PMID 24628071 DOI: 10.1111/1346-8138.12321  0.01
2014 Sakai N, Sakai T, Hirota T, Watanabe Y, Ceccarelli C, Kahane C, Bottinelli S, Caux E, Demyk K, Vastel C, Coutens A, Taquet V, Ohashi N, Takakuwa S, Yen HW, et al. Change in the chemical composition of infalling gas forming a disk around a protostar. Nature. 507: 78-80. PMID 24522533 DOI: 10.1038/nature13000  0.01
2014 Hirota T, Schwartz S, Correll CU. Alpha-2 agonists for attention-deficit/hyperactivity disorder in youth: a systematic review and meta-analysis of monotherapy and add-on trials to stimulant therapy. Journal of the American Academy of Child and Adolescent Psychiatry. 53: 153-73. PMID 24472251 DOI: 10.1016/j.jaac.2013.11.009  0.01
2014 Sumida T, Tsuboi H, Iizuka M, Hirota T, Asashima H, Matsumoto I. The role of M3 muscarinic acetylcholine receptor reactive T cells in Sjögren's syndrome: a critical review. Journal of Autoimmunity. 51: 44-50. PMID 24397962 DOI: 10.1016/j.jaut.2013.12.012  0.01
2014 Hayashi M, Hirota T, Saeki H, Nakagawa H, Ishiuji Y, Matsuzaki H, Tsunemi Y, Kato T, Shibata S, Sugaya M, Sato S, Tada Y, Doi S, Miyatake A, Ebe K, et al. Genetic polymorphism in the TRAF3IP2 gene is associated with psoriasis vulgaris in a Japanese population. Journal of Dermatological Science. 73: 264-5. PMID 24373565 DOI: 10.1016/j.jdermsci.2013.11.012  0.01
2014 Tanaka S, Hirota T, Kamijo A, Ishii H, Hatsushika K, Fujieda S, Ishitoya J, Masuyama K, Tamari M. Lung functions of Japanese patients with chronic rhinosinusitis who underwent endoscopic sinus surgery. Allergology International : Official Journal of the Japanese Society of Allergology. 63: 27-35. PMID 24270225 DOI: 10.2332/allergolint.13-OA-0579  0.01
2014 Gallego-Paez LM, Tanaka H, Bando M, Takahashi M, Nozaki N, Nakato R, Shirahige K, Hirota T. Smc5/6-mediated regulation of replication progression contributes to chromosome assembly during mitosis in human cells. Molecular Biology of the Cell. 25: 302-17. PMID 24258023 DOI: 10.1091/mbc.E13-01-0020  0.01
2014 Tsuboi H, Asashima H, Takai C, Hagiwara S, Hagiya C, Yokosawa M, Hirota T, Umehara H, Kawakami A, Nakamura H, Sano H, Tsubota K, Ogawa Y, Takamura E, Saito I, et al. Primary and secondary surveys on epidemiology of Sjögren's syndrome in Japan. Modern Rheumatology / the Japan Rheumatism Association. 24: 464-70. PMID 24252039 DOI: 10.3109/14397595.2013.843765  0.01
2014 Hagiya C, Tsuboi H, Yokosawa M, Hagiwara S, Hirota T, Takai C, Asashima H, Miki H, Umeda N, Horikoshi M, Kondo Y, Sugihara M, Ogishima H, Suzuki T, Hiraoka T, et al. Clinicopathological features of IgG4-related disease complicated with orbital involvement. Modern Rheumatology / the Japan Rheumatism Association. 24: 471-6. PMID 24252013 DOI: 10.3109/14397595.2013.844307  0.01
2014 Hirota T, Veenstra-Vanderweele J, Hollander E, Kishi T. Antiepileptic medications in autism spectrum disorder: a systematic review and meta-analysis. Journal of Autism and Developmental Disorders. 44: 948-57. PMID 24077782 DOI: 10.1007/s10803-013-1952-2  0.01
2014 Shiroto A, Satoh T, Hirota T. Polygyny increases survival of minor workers and mortality of major workers in overwintering Camponotus yamaokai (hymenoptera: Formicidae) Annals of the Entomological Society of America. 107: 702-707. DOI: 10.1603/AN13063  0.01
2014 Tomimatsu M, Hirota T, Hardin T, Todeschini P. Embrittlement of reactor pressure vessels (RPVs) in pressurized water reactors (PWRs) Irradiation Embrittlement of Reactor Pressure Vessels (Rpvs) in Nuclear Power Plants. 57-106. DOI: 10.1533/9780857096470.2.57  0.01
2014 Hirota T, Sakamoto H, Ogawa N. Proposal for update on evaluation procedure for reactor pressure vessels against pressurized thermal shock events in Japan American Society of Mechanical Engineers, Pressure Vessels and Piping Division (Publication) Pvp. 1. DOI: 10.1115/PVP201428392  0.01
2014 Ito M, Hosodani K, Itoh K, Betsudan SI, Makino S, Hirota T, Noguchi K, Taniguchi E. High efficient bridge rectifiers in 100MHz and 2.4GHz bands Ieee Wireless Power Transfer Conference 2014, Ieee Wptc 2014. 64-67. DOI: 10.1109/WPT.2014.6839595  0.01
2014 Kaneko G, Inoue S, Taniguchi K, Hirota T, Kamiya Y, Daisho Y, Inami S. Analysis of degradation mechanism of lithium iron phosphate battery 2013 World Electric Vehicle Symposium and Exhibition, Evs 2014. DOI: 10.1109/EVS.2013.6914847  0.01
2014 Tanaka K, Kimura S, Miyasaka Y, Hirota T, Kamiya Y, Daisho Y. Design, manufacture, and environmental sustainability evaluations of advanced electric medium duty bus 'WEB for Suntory' 2013 World Electric Vehicle Symposium and Exhibition, Evs 2014. DOI: 10.1109/EVS.2013.6914826  0.01
2014 Makino S, Hayashi H, Moroya T, Itoh K, Noguchi K, Hirota T. Dual band characteristics of a linear antenna over a capacitance grid type AMC substrate 2014 Ieee-Aps Topical Conference On Antennas and Propagation in Wireless Communications, Apwc 2014. 93-96. DOI: 10.1109/APWC.2014.6905526  0.01
2014 Fujisawa K, Takase G, Kimura S, Aoki N, Nagadomi Y, Shimomura T, Sugiyama K, Motogi K, Niinuma K, Hirota T, Yonekura Y. Periodic flare of the 6.7-GHz methanol maser in IRAS22198+6336 Publications of the Astronomical Society of Japan. 66. DOI: 10.1093/pasj/psu053  0.01
2014 Fujisawa K, Sugiyama K, Motogi K, Hachisuka K, Yonekura Y, Sawada-Satoh S, Matsumoto N, Sorai K, Momose M, Saito Y, Takaba H, Ogawa H, Kimura K, Niinuma K, Hirano D, ... ... Hirota T, et al. Observations of 6.7GHz methanol masers with east-asian VLBI network. I. VLBI images of the first epoch of observations Publications of the Astronomical Society of Japan. 66. DOI: 10.1093/pasj/psu015  0.01
2014 Min C, Matsumoto N, Kim MK, Hirota T, Shibata KM, Cho SH, Shizugami M, Honma M. Accurate parallax measurement toward the symbiotic star R Aquarii Publications of the Astronomical Society of Japan. 66. DOI: 10.1093/pasj/psu003  0.01
2014 Tatematsu K, Ohashi S, Umemoto T, Lee JE, Hirota T, Yamamoto S, Choi M, Kandori R, Mizuno N. Chemical variation in molecular cloud cores in the Orion A cloud. II. Publications of the Astronomical Society of Japan. 66. DOI: 10.1093/pasj/pst016  0.01
2014 Yanagida T, Sakai T, Hirota T, Sakai N, Foster JB, Sanhueza P, Jackson JM, Furuya K, Aikawa Y, Yamamoto S. Alma observations of the IRDC clump G34.43+00.24 MM3: 278 GHz class i methanol masers Astrophysical Journal Letters. 794. DOI: 10.1088/2041-8205/794/1/L10  0.01
2014 Sakai N, Oya Y, Sakai T, Watanabe Y, Hirota T, Ceccarelli C, Kahane C, Lopez-Sepulcre A, Lefloch B, Vastel C, Bottinelli S, Caux E, Coutens A, Aikawa Y, Takakuwa S, et al. A chemical view of protostellar-disk formation in L1527 Astrophysical Journal Letters. 791. DOI: 10.1088/2041-8205/791/2/L38  0.01
2014 Nakamura F, Sugitani K, Tanaka T, Nishitani H, Dobashi K, Shimoikura T, Shimajiri Y, Kawabe R, Yonekura Y, Mizuno I, Kimura K, Tokuda K, Kozu M, Okada N, Hasegawa Y, ... ... Hirota T, et al. Cluster formation triggered by filament collisions in Serpens South Astrophysical Journal Letters. 791. DOI: 10.1088/2041-8205/791/2/L23  0.01
2014 Hirota T, Kim MK, Kurono Y, Honma M. A hot molecular circumstellar disk around the massive protostar orion source i Astrophysical Journal Letters. 782. DOI: 10.1088/2041-8205/782/2/L28  0.01
2014 Kamezaki T, Imura K, Omodaka T, Handa T, Tsuboi Y, Nagayama T, Hirota T, Sunada K, Kobayashi H, Chibueze JO, Kawai E, Nakano M. Annual parallax determination toward a new x-ray-emitting class 0 candidate with the water maser in the NGC 2264 star-forming region Astrophysical Journal, Supplement Series. 211. DOI: 10.1088/0067-0049/211/2/18  0.01
2014 Oya Y, Sakai N, Sakai T, Watanabe Y, Hirota T, Lindberg JE, Bisschop SE, Jørgensen JK, Van Dishoeck EF, Yamamoto S. A substellar-mass protostar and its outflow of IRAS 15398-3359 revealed by subarcsecond-resolution observations of H2CO and CCH Astrophysical Journal. 795. DOI: 10.1088/0004-637X/795/2/152  0.01
2014 Tatematsu K, Hirota T, Ohashi S, Choi M, Lee JE, Yamamoto S, Umemoto T, Kandori R, Kang M, Mizuno N. Thermal starless ammonia core surrounded by CCS in the orion a cloud Astrophysical Journal. 789. DOI: 10.1088/0004-637X/789/1/83  0.01
2014 Suzuki T, Ohishi M, Hirota T. Distribution of CCS and HC3N in L1147, an early phase dark cloud Astrophysical Journal. 788. DOI: 10.1088/0004-637X/788/2/108  0.01
2014 Chibueze JO, Omodaka T, Handa T, Imai H, Kurayama T, Nagayama T, Sunada K, Nakano M, Hirota T, Honma M. Astrometry and spatio-kinematics of H2O masers in the massive star-forming region NGC 6334i(north) with vera Astrophysical Journal. 784. DOI: 10.1088/0004-637X/784/2/114  0.01
2014 Iwata Y, Hirota T, Yazaki T, Iwasaki A, Suzuki T, Inoue S, Usuki K. Effects of saturated hydraulic conductivity on volunteer potato (Solanum tuberosum L.) tuber survival Soil Science and Plant Nutrition. DOI: 10.1080/00380768.2014.982491  0.01
2014 Saeki H, Hirota T, Nakagawa H, Tsunemi Y, Kato T, Shibata S, Sugaya M, Sato S, Doi S, Miyatake A, Ebe K, Noguchi E, Ebihara T, Amagai M, Esaki H, et al. Corrigendum to "Genetic polymorphisms in the IL22 gene are associated with psoriasis vulgaris in a Japanese population" [J. Dermatol. Sci. 71 (2013) 148-150] Journal of Dermatological Science. 74: 95. DOI: 10.1016/j.jdermsci.2013.10.007  0.01
2014 Yanai Y, Hirota T, Iwata Y, Nemoto M, Koga N, Nagata O, Ohkubo S. Snow cover manipulation in agricultural fields: As an option for mitigating greenhouse gas emissions Ecological Research. 29: 535-545. DOI: 10.1007/s11284-014-1127-4  0.01
2014 Okuda K, Takano JI, Hirota T, Sasaki K. Polycyclic N-heterocyclic compounds 83: Synthesis of 2,4-disubstituted 5,6-dihydro[1]benzofuro[3′,2′:2,3]oxepino[4,5-d]pyrimidines and 2,4,5-Trisubstituted 5,6-Dihydro[1]benzofuro[2′,3′:5,6]pyrano[4,3-d] pyrimidines from 4-Chloro-5,6-dihydro[1]benzofuro[3′,2′:2,3] oxepino[4,5-d]pyrimidines Journal of Heterocyclic Chemistry. 51: 788-793. DOI: 10.1002/jhet.1900  0.01
2014 Okuda K, Hirota T, Sasaki K. Polycyclic N-heterocyclic compounds. Part 82: Synthesis and evaluation of anti-platelet aggregation activity of 2,4-disubstituted 5,6-dihydro[1] benzothiepino[5,4-d]pyrimidine and related compounds Journal of Heterocyclic Chemistry. 51: 911-920. DOI: 10.1002/jhet.1741  0.01
2014 Okuda K, Hirota T, Sasaki K. Polycyclic N-heterocyclic compounds. Part 79: Synthesis of 2,4-disubstituted 6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidines as potential antiplatelet aggregators Journal of Heterocyclic Chemistry. 51: 1607-1614. DOI: 10.1002/jhet.1714  0.01
2014 Okuda K, Itsuji Y, Hirota T, Sasaki K. Polycyclic N-heterocyclic compounds. Part 80: Synthesis and evaluation of effects on in vitro pentosidine formation of 5,6-dihydro[1]benzothieno[3′, 2′:2,3]thiepino[4,5-d]pyrimidine and related compounds Journal of Heterocyclic Chemistry. 51: 891-898. DOI: 10.1002/jhet.1709  0.01
2014 Okuda K, Zhang YX, Hirota T, Sasaki K. Polycyclic N-heterocyclic compounds. Part 78: Synthesis of N-[2-([1,2,4]oxadiazol-5-yl)cyclohepten-1-yl]formamide oximes and their evaluation as inhibitors of platelet aggregation Journal of Heterocyclic Chemistry. 51: 518-522. DOI: 10.1002/jhet.1628  0.01
2014 Okuda K, Yamamoto Y, Hirota T, Sasaki K. Polycyclic N-heterocyclic compounds. Part 75: Synthesis of 2,4-disubstituted 5,6-dihydro[1]benzoxepino[5,4-d]pyrimidines and 12-substituted 1,2,4,5-tetrahydro[1]benzoxepino[4,5-e]imidazo[1,2-c]pyrimidines as potential antiplatelet aggregators Journal of Heterocyclic Chemistry. 51: 972-981. DOI: 10.1002/jhet.1559  0.01
2014 Okuda K, Takano JI, Hirota T, Sasaki K, Nishina Y, Ishida H. Polycyclic N-heterocyclic compounds 76: Synthesis and antiplatelet evaluation of 2,4-disubstituted 5,6-Dihydro[1]benzofuro[3′,2′:2,3] oxepino[4,5-d]pyrimidines Journal of Heterocyclic Chemistry. 51: 661-668. DOI: 10.1002/jhet.1539  0.01
2014 Sato H, Hirota T, Hiramitsu A, Tanaka M. Subjective evaluation of floor impact sound of wood-frame construction dwellings in different living situation Internoise 2014 - 43rd International Congress On Noise Control Engineering: Improving the World Through Noise Control 0.01
2014 Sakashita M, Makino Y, Noguchi E, Hirota T, Tamari M, Fujieda S. Clinical relevance of biomarkers in allergic rhinitis Japanese Journal of Allergology. 63: 767-774.  0.01
2014 Tatematsu K, Hirota T, Suzuki H, Taniguchi M, Nunoi Y, Uzawa T. Influence of temperature and moisture on aging of glass wool Journal of Environmental Engineering (Japan). 79: 753-762.  0.01
2014 Hama H, Hashimoto J, Itoh K, Noguchi K, Hirota T, Makino S. Implementation of the even harmonic mixer driven by the pulsed LO 2014 Asia-Pacific Microwave Conference Proceedings, Apmc 2014. 889-891.  0.01
2014 Ando Y, Hirota T. A subgridding technique for the CIP method Ieee International Symposium On Electromagnetic Compatibility. 2014: 801-804.  0.01
2014 Iijima H, Yamada H, Yatagai Y, Kaneko Y, Naito T, Sakamoto T, Masuko H, Hirota T, Tamari M, Konno S, Nishimura M, Hizawa N. Effects of thymic stromal lymphopoietin (TSLP) genotypes on asthma phenotypes defined by the atopy cluster-influence of smoking habits Japanese Journal of Allergology. 63: 33-44.  0.01
2013 Hirota T, Kishi T. Prophylactic antipsychotic use for postoperative delirium: a systematic review and meta-analysis. The Journal of Clinical Psychiatry. 74: e1136-44. PMID 24434102 DOI: 10.4088/JCP.13r08512  0.01
2013 Ando K, Ozaki T, Hirota T, Nakagawara A. NFBD1/MDC1 is phosphorylated by PLK1 and controls G2/M transition through the regulation of a TOPOIIα-mediated decatenation checkpoint. Plos One. 8: e82744. PMID 24349352 DOI: 10.1371/journal.pone.0082744  0.01
2013 Yatagai Y, Sakamoto T, Masuko H, Kaneko Y, Yamada H, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Imoto Y, Tokunaga T, Fujieda S, Konno S, Nishimura M, et al. Genome-wide association study for levels of total serum IgE identifies HLA-C in a Japanese population. Plos One. 8: e80941. PMID 24324648 DOI: 10.1371/journal.pone.0080941  0.01
2013 Yoshimura B, Hirota T, Takaki M, Kishi Y. Is quetiapine suitable for treatment of acute schizophrenia with catatonic stupor? A case series of 39 patients. Neuropsychiatric Disease and Treatment. 9: 1565-71. PMID 24143105 DOI: 10.2147/NDT.S52311  0.01
2013 Miyajima A, Okamoto M, Muto T, Hirota T. Disruption of elastic lamellae in aorta and dysfunction of vaso-regulation by rofecoxib in rats. The Journal of Toxicological Sciences. 38: 719-29. PMID 24025789 DOI: DN/JST.JSTAGE/jts/38.719  0.01
2013 Muto T, Miyajima A, Bamba M, Hirota T. Disruption of elastic lamellae in the aorta by D-penicillamine and its effect on vaso-regulation in rats. The Journal of Toxicological Sciences. 38: 707-17. PMID 24025788 DOI: DN/JST.JSTAGE/jts/38.707  0.01
2013 Saito J, Hirota T, Furuta S, Kobayashi D, Takane H, Ieiri I. Association between DNA methylation in the miR-328 5'-flanking region and inter-individual differences in miR-328 and BCRP expression in human placenta. Plos One. 8: e72906. PMID 23991164 DOI: 10.1371/journal.pone.0072906  0.01
2013 Gotanda K, Hirota T, Matsumoto N, Ieiri I. MicroRNA-433 negatively regulates the expression of thymidylate synthase (TYMS) responsible for 5-fluorouracil sensitivity in HeLa cells. Bmc Cancer. 13: 369. PMID 23915286 DOI: 10.1186/1471-2407-13-369  0.01
2013 Satow S, Satoh T, Hirota T. Colony fusion in a parthenogenetic ant, Pristomyrmex punctatus. Journal of Insect Science (Online). 13: 38. PMID 23895053 DOI: 10.1673/031.013.3801  0.01
2013 Hirota T, Kishi T. Adenosine hypothesis in schizophrenia and bipolar disorder: a systematic review and meta-analysis of randomized controlled trial of adjuvant purinergic modulators. Schizophrenia Research. 149: 88-95. PMID 23870805 DOI: 10.1016/j.schres.2013.06.038  0.01
2013 Satow S, Saitow Y, Yamaki S, Hirota T. Japanese queenless ants, Pristomyrmex punctatus, prefer the traces of both nestmates and strangers in nest selection. Zoological Science. 30: 525-8. PMID 23829211 DOI: 10.2108/zsj.30.525  0.01
2013 Kanemitsu Y, Matsumoto H, Izuhara K, Tohda Y, Kita H, Horiguchi T, Kuwabara K, Tomii K, Otsuka K, Fujimura M, Ohkura N, Tomita K, Yokoyama A, Ohnishi H, Nakano Y, ... ... Hirota T, et al. Increased periostin associates with greater airflow limitation in patients receiving inhaled corticosteroids. The Journal of Allergy and Clinical Immunology. 132: 305-12.e3. PMID 23791506 DOI: 10.1016/j.jaci.2013.04.050  0.01
2013 Hirota T, Tamari M. [Genomic biomarker]. ArerugÄ« = [Allergy]. 62: 532-9. PMID 23760197  0.01
2013 Ellinghaus D, Baurecht H, Esparza-Gordillo J, Rodríguez E, Matanovic A, Marenholz I, Hübner N, Schaarschmidt H, Novak N, Michel S, Maintz L, Werfel T, Meyer-Hoffert U, Hotze M, Prokisch H, ... ... Hirota T, et al. High-density genotyping study identifies four new susceptibility loci for atopic dermatitis. Nature Genetics. 45: 808-12. PMID 23727859 DOI: 10.1038/ng.2642  0.01
2013 Saeki H, Hirota T, Nakagawa H, Tsunemi Y, Kato T, Shibata S, Sugaya M, Sato S, Doi S, Miyatake A, Ebe K, Noguchi E, Ebihara T, Amagai M, Esaki H, et al. Genetic polymorphisms in the IL22 gene are associated with psoriasis vulgaris in a Japanese population. Journal of Dermatological Science. 71: 148-50. PMID 23664643 DOI: 10.1016/j.jdermsci.2013.04.002  0.01
2013 Nakamura T, Hirota T, Mizushima K, Ohki K, Naito Y, Yamamoto N, Yoshikawa T. Milk-derived peptides, Val-Pro-Pro and Ile-Pro-Pro, attenuate atherosclerosis development in apolipoprotein e-deficient mice: a preliminary study. Journal of Medicinal Food. 16: 396-403. PMID 23631494 DOI: 10.1089/jmf.2012.2541  0.01
2013 Kubo T, Kitaoka H, Yamanaka S, Hirota T, Baba Y, Hayashi K, Iiyama T, Kumagai N, Tanioka K, Yamasaki N, Matsumura Y, Furuno T, Sugiura T, Doi YL. Significance of high-sensitivity cardiac troponin T in hypertrophic cardiomyopathy. Journal of the American College of Cardiology. 62: 1252-9. PMID 23623916 DOI: 10.1016/j.jacc.2013.03.055  0.01
2013 Kishi T, Hirota T, Iwata N. Add-on fluvoxamine treatment for schizophrenia: an updated meta-analysis of randomized controlled trials. European Archives of Psychiatry and Clinical Neuroscience. 263: 633-41. PMID 23605347 DOI: 10.1007/s00406-013-0406-3  0.01
2013 Goto H, Sagitani A, Ashida N, Kato S, Hirota T, Shinoda T, Yamamoto N. Anti-influenza virus effects of both live and non-live Lactobacillus acidophilus L-92 accompanied by the activation of innate immunity. The British Journal of Nutrition. 110: 1810-8. PMID 23594927 DOI: 10.1017/S0007114513001104  0.01
2013 Earnshaw WC, Allshire RC, Black BE, Bloom K, Brinkley BR, Brown W, Cheeseman IM, Choo KH, Copenhaver GP, Deluca JG, Desai A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D, ... ... Hirota T, et al. Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Research : An International Journal On the Molecular, Supramolecular and Evolutionary Aspects of Chromosome Biology. 21: 101-6. PMID 23580138 DOI: 10.1007/s10577-013-9347-y  0.01
2013 Itoh G, Sugino S, Ikeda M, Mizuguchi M, Kanno S, Amin MA, Iemura K, Yasui A, Hirota T, Tanaka K. Nucleoporin Nup188 is required for chromosome alignment in mitosis. Cancer Science. 104: 871-9. PMID 23551833 DOI: 10.1111/cas.12159  0.01
2013 Ando Y, Shimada H, Matsumoto N, Hirota T, Oribe M, Otsuka E, Ishii K, Morimoto T, Ohashi K, Ieiri I. Role of methotrexate polyglutamation and reduced folate carrier 1 (RFC1) gene polymorphisms in clinical assessment indexes. Drug Metabolism and Pharmacokinetics. 28: 442-5. PMID 23545592 DOI: DN/JST.JSTAGE/dmpk/DMPK-12-RG-128  0.01
2013 Tamari M, Tanaka S, Hirota T. Genome-wide association studies of allergic diseases. Allergology International : Official Journal of the Japanese Society of Allergology. 62: 21-8. PMID 23439055 DOI: 10.2332/allergolint.13-RAI-0539  0.01
2013 Ieiri I, Tsunemitsu S, Maeda K, Ando Y, Izumi N, Kimura M, Yamane N, Okuzono T, Morishita M, Kotani N, Kanda E, Deguchi M, Matsuguma K, Matsuki S, Hirota T, et al. Mechanisms of pharmacokinetic enhancement between ritonavir and saquinavir; micro/small dosing tests using midazolam (CYP3A4), fexofenadine (p-glycoprotein), and pravastatin (OATP1B1) as probe drugs. Journal of Clinical Pharmacology. 53: 654-61. PMID 23381882 DOI: 10.1002/jcph.62  0.01
2013 Hirota T, Fujita M, Matsumoto T, Higuchi T, Shiraishi T, Minami M, Okumura M, Nabeshima K, Watanabe K. Pleuroparenchymal fibroelastosis as a manifestation of chronic lung rejection? The European Respiratory Journal. 41: 243-5. PMID 23277524 DOI: 10.1183/09031936.00103912  0.01
2013 Iijima H, Kaneko Y, Yamada H, Yatagai Y, Masuko H, Sakamoto T, Naito T, Hirota T, Tamari M, Konno S, Nishimura M, Noguchi E, Hizawa N. A distinct sensitization pattern associated with asthma and the thymic stromal lymphopoietin (TSLP) genotype. Allergology International : Official Journal of the Japanese Society of Allergology. 62: 123-30. PMID 23267211 DOI: 10.2332/allergolint.12-OA-0488  0.01
2013 Kagiwada S, Kurimoto K, Hirota T, Yamaji M, Saitou M. Replication-coupled passive DNA demethylation for the erasure of genome imprints in mice. The Embo Journal. 32: 340-53. PMID 23241950 DOI: 10.1038/emboj.2012.331  0.01
2013 Hirota T, Eguchi S, Ieiri I. Impact of genetic polymorphisms in CYP2C9 and CYP2C19 on the pharmacokinetics of clinically used drugs. Drug Metabolism and Pharmacokinetics. 28: 28-37. PMID 23165865 DOI: DN/JST.JSTAGE/dmpk/DMPK-12-RV-085  0.01
2013 Tomita K, Sakashita M, Hirota T, Tanaka S, Masuyama K, Yamada T, Fujieda S, Miyatake A, Hizawa N, Kubo M, Nakamura Y, Tamari M. Variants in the 17q21 asthma susceptibility locus are associated with allergic rhinitis in the Japanese population. Allergy. 68: 92-100. PMID 23157251 DOI: 10.1111/all.12066  0.01
2013 Yamaide F, Undarmaa S, Mashimo Y, Shimojo N, Arima T, Morita Y, Hirota T, Fujita K, Miyatake A, Doi S, Sato K, Suzuki S, Nishimuta T, Watanabe H, Hoshioka A, et al. Association study of matrix metalloproteinase-12 gene polymorphisms and asthma in a Japanese population. International Archives of Allergy and Immunology. 160: 287-96. PMID 23075521 DOI: 10.1159/000341672  0.01
2013 Matsumoto T, Fujita M, Hirota T, Takeda S, Hirano R, Uchino J, Harada T, Watanabe K. Elevation of serum C-reactive protein predicts failure of the initial antimicrobial treatment for febrile neutropenia with lung cancer. Journal of Infection and Chemotherapy : Official Journal of the Japan Society of Chemotherapy. 19: 202-7. PMID 23053498 DOI: 10.1007/s10156-012-0474-8  0.01
2013 Suzuki T, Horikoshi M, Sugihara M, Hirota T, Ogishima H, Umeda N, Kondo Y, Tsuboi H, Hayashi T, Chino Y, Matsumoto I, Sumida T. Therapeutic efficacy of tocilizumab in patients with rheumatoid arthritis refractory to anti-tumor-necrosis-factor inhibitors: 1 year follow-up with low-field extremity MRI. Modern Rheumatology / the Japan Rheumatism Association. 23: 782-7. PMID 22975733 DOI: 10.1007/s10165-012-0746-2  0.01
2013 Iwata Y, Yazaki T, Suzuki S, Hirota T. Water and nitrate movements in an agricultural field with different soil frost depths: Field experiments and numerical simulation Annals of Glaciology. 54: 157-165. DOI: 10.3189/2013AoG62A204  0.01
2013 Hirota T, Hirano T, Onizawa K. Alternative reference temperature based on master curve approach in Japanese reactor pressure vessel steel American Society of Mechanical Engineers, Pressure Vessels and Piping Division (Publication) Pvp. 1. DOI: 10.1115/PVP2013-98164  0.01
2013 Yoshimoto K, Hirota T, Sakamoto H, Sugihara T, Sakaguchi S, Oumaya T. Applicability of miniature C(T) specimen to evaluation of fracture toughness for reactor pressure vessel steel American Society of Mechanical Engineers, Pressure Vessels and Piping Division (Publication) Pvp. 6. DOI: 10.1115/PVP2013-97840  0.01
2013 Ogawa N, Yoshimoto K, Hirota T, Sakaguchi S, Oumaya T. Evaluation on constraint effect of reactor pressure vessel under pressurized thermal shock American Society of Mechanical Engineers, Pressure Vessels and Piping Division (Publication) Pvp. 1. DOI: 10.1115/PVP2013-97566  0.01
2013 Noguchi K, Makino S, Hirota T, Itoh K, Betsudan SI. Theoretical bandwidth of folded small antennas Ieee Antennas and Propagation Society, Ap-S International Symposium (Digest). 766-767. DOI: 10.1109/APS.2013.6711042  0.01
2013 Hashimoto J, Itoh K, Noguchi K, Hirota T, Makino S, Betsudan SI. High linear even harmonic mixer driven by the pulsed LO Asia-Pacific Microwave Conference Proceedings, Apmc. 173-175. DOI: 10.1109/APMC.2013.6695084  0.01
2013 Sakai T, Sakai N, Foster JB, Sanhueza P, Jackson JM, Kassis M, Furuya K, Aikawa Y, Hirota T, Yamamoto S. Alma observations of the irdc clump G34.43+00.24 Mm3: Hot core and molecular outflows Astrophysical Journal Letters. 775. DOI: 10.1088/2041-8205/775/1/L31  0.01
2013 Yazaki T, Hirota T, Iwata Y, Inoue S, Usuki K, Suzuki T, Shirahata M, Iwasaki A, Kajiyama T, Araki K, Takamiya Y, Maezuka K. Effective killing of volunteer potato (Solanum tuberosum L.) tubers by soil frost control using agrometeorological information-An adaptive countermeasure to climate change in a cold region Agricultural and Forest Meteorology. 182: 91-100. DOI: 10.1016/j.agrformet.2013.08.005  0.01
2013 Hirota T, Tamari M. Genetics of asthma Respiration and Circulation. 61: 906-913.  0.01
2012 Matsumoto T, Takebayashi J, Ishimi Y, Ozawa C, Sano A, Hirota T, Endoh K. Evaluation of cyanocobalamin in multivitamin tablets and their Standard Reference Material 3280 by HPLC with visible detection. Journal of Aoac International. 95: 1609-13. PMID 23451375  0.01
2012 Okuda K, Hirota T, Nishina Y, Ishida H. 10'-Chloro-3',4'-dihydro-2'H-spiro-[cyclo-propane-1,7'(6'H)-pyrimido[2,1-a]isoquinolin]-6'-one. Acta Crystallographica. Section E, Structure Reports Online. 68: o3252. PMID 23284549 DOI: 10.1107/S1600536812044261  0.01
2012 Hirota T, Sayama T, Yamasaki M, Sasama H, Sugimoto T, Ishimoto M, Yoshida S. Diversity and population structure of black soybean landraces originating from Tanba and neighboring regions. Breeding Science. 61: 593-601. PMID 23136497 DOI: 10.1270/jsbbs.61.593  0.01
2012 Kumasaka N, Aoki M, Okada Y, Takahashi A, Ozaki K, Mushiroda T, Hirota T, Tamari M, Tanaka T, Nakamura Y, Kamatani N, Kubo M. Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population. Plos One. 7: e44507. PMID 23049750 DOI: 10.1371/journal.pone.0044507  0.01
2012 Hirota T, Takahashi A, Kubo M, Tsunoda T, Tomita K, Sakashita M, Yamada T, Fujieda S, Tanaka S, Doi S, Miyatake A, Enomoto T, Nishiyama C, Nakano N, Maeda K, et al. Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population. Nature Genetics. 44: 1222-6. PMID 23042114 DOI: 10.1038/ng.2438  0.01
2012 Watanabe K, Nagata N, Kitasato Y, Wakamatsu K, Nabeshima K, Harada T, Hirota T, Shiraishi M, Fujita M. Rapid decrease in forced vital capacity in patients with idiopathic pulmonary upper lobe fibrosis. Respiratory Investigation. 50: 88-97. PMID 23021767 DOI: 10.1016/j.resinv.2012.06.003  0.01
2012 Okuda K, Hirota T, Nishina Y, Ishida H. 3-(2-Oxo-2,3,4,5-tetra-hydro-furan-3-yl)-1-benzofuran-2-carbonitrile. Acta Crystallographica. Section E, Structure Reports Online. 68: o2819. PMID 22969689 DOI: 10.1107/S1600536812036835  0.01
2012 Deardorff MA, Bando M, Nakato R, Watrin E, Itoh T, Minamino M, Saitoh K, Komata M, Katou Y, Clark D, Cole KE, De Baere E, Decroos C, Di Donato N, Ernst S, ... ... Hirota T, et al. HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycle. Nature. 489: 313-7. PMID 22885700 DOI: 10.1038/nature11316  0.01
2012 Ieiri I, Fukae M, Maeda K, Ando Y, Kimura M, Hirota T, Nakamura T, Iwasaki K, Matsuki S, Matsuguma K, Kanda E, Deguchi M, Irie S, Sugiyama Y. Pharmacogenomic/pharmacokinetic assessment of a four-probe cocktail for CYPs and OATPs following oral microdosing. International Journal of Clinical Pharmacology and Therapeutics. 50: 689-700. PMID 22853867 DOI: 10.5414/CP201763  0.01
2011 Hatta J, Hatta T, Miyagawa S, Kitahara Y, Hirota T, Anzawa K, Mochizuki T. Quantitative analysis of the effects of antimycotic agents on the hyphal growth of Trichophyton rubrum: a preliminary study. Mycoses. 54: e84-91. PMID 20202117 DOI: 10.1111/j.1439-0507.2009.01849.x  0.01
2007 Kido H, Yasukawa H, Hirota T, Shindo A, Naruse T. Decrease in rat internal anal pressure with the use of a topical ointment containing a killed E. coli culture suspension. International Journal of Colorectal Disease. 22: 271-6. PMID 16628409 DOI: 10.1007/s00384-006-0123-8  0.01
2002 Horisawa E, Hirota T, Kawazoe S, Yamada J, Yamamoto H, Takeuchi H, Kawashima Y. Prolonged anti-inflammatory action of DL-lactide/glycolide copolymer nanospheres containing betamethasone sodium phosphate for an intra-articular delivery system in antigen-induced arthritic rabbit. Pharmaceutical Research. 19: 403-10. PMID 12033371  0.01
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