| Year |
Citation |
Score |
| 2023 |
Vidalle MC, Sheth B, Fazio A, Marvi MV, Leto S, Koufi FD, Neri I, Casalin I, Ramazzotti G, Follo MY, Ratti S, Manzoli L, Gehlot S, Divecha N, Fiume R. Nuclear Phosphoinositides as Key Determinants of Nuclear Functions. Biomolecules. 13. PMID 37509085 DOI: 10.3390/biom13071049 |
0.353 |
|
| 2023 |
Poli A, Pennacchio FA, Ghisleni A, di Gennaro M, Lecacheur M, Nastały P, Crestani M, Pramotton FM, Iannelli F, Beznusenko G, Mironov AA, Panzetta V, Fusco S, Sheth B, Poulikakos D, ... ... Divecha N, et al. PIP4K2B is mechanoresponsive and controls heterochromatin-driven nuclear softening through UHRF1. Nature Communications. 14: 1432. PMID 36918565 DOI: 10.1038/s41467-023-37064-0 |
0.412 |
|
| 2021 |
Bowler-Barnett E, Martinez-Garcia FD, Sherwood M, Aleidan A, John S, Weston S, Wang Y, Divecha N, Skipp P, Ewing RM. Proteomic characterization of GSK3β knockout shows altered cell adhesion and metabolic pathway utilisation in colorectal cancer cells. Plos One. 16: e0246707. PMID 34739494 DOI: 10.1371/journal.pone.0246707 |
0.315 |
|
| 2021 |
Poli A, Abdul-Hamid S, Zaurito AE, Campagnoli F, Bevilacqua V, Sheth B, Fiume R, Pagani M, Abrignani S, Divecha N. PIP4Ks impact on PI3K, FOXP3, and UHRF1 signaling and modulate human regulatory T cell proliferation and immunosuppressive activity. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34312224 DOI: 10.1073/pnas.2010053118 |
0.316 |
|
| 2020 |
Poli A, Fiume R, Mongiorgi S, Zaurito A, Sheth B, Vidalle MC, Hamid SA, Kimber S, Campagnoli F, Ratti S, Rusciano I, Faenza I, Manzoli L, Divecha N. Exploring the controversial role of PI3K signalling in CD4 regulatory T (T-Reg) cells. Advances in Biological Regulation. 100722. PMID 32362560 DOI: 10.1016/J.Jbior.2020.100722 |
0.367 |
|
| 2019 |
Bowler EH, Smith-Vidal A, Lester A, Bell J, Wang Z, Bell CG, Wang Y, Divecha N, Skipp PJ, Ewing RM. Deep proteomic analysis of Dnmt1 mutant/hypomorphic colorectal cancer cells reveals dysregulation of epithelial-mesenchymal transition and subcellular re-localization of Beta-Catenin. Epigenetics. 1-15. PMID 31448663 DOI: 10.1080/15592294.2019.1656154 |
0.352 |
|
| 2019 |
Fiume R, Faenza I, Sheth B, Poli A, Vidalle MC, Mazzetti C, Abdul SH, Campagnoli F, Fabbrini M, Kimber ST, Mariani GA, Xian J, Marvi MV, Mongiorgi S, Shah Z, ... Divecha N, et al. Nuclear Phosphoinositides: Their Regulation and Roles in Nuclear Functions. International Journal of Molecular Sciences. 20. PMID 31248120 DOI: 10.3390/Ijms20122991 |
0.43 |
|
| 2019 |
Poli A, Zaurito AE, Abdul-Hamid S, Fiume R, Faenza I, Divecha N. Phosphatidylinositol 5 Phosphate (PI5P): From Behind the Scenes to the Front (Nuclear) Stage. International Journal of Molecular Sciences. 20. PMID 31035587 DOI: 10.3390/Ijms20092080 |
0.484 |
|
| 2019 |
Bowler EH, Bell J, Divecha N, Skipp P, Ewing RM. Proteomic analysis of Azacitidine-induced degradation profiles identifies multiple chromatin and epigenetic regulators including Uhrf1 and Dnmt1 as sensitive to Azacitidine. Journal of Proteome Research. PMID 30672294 DOI: 10.1021/Acs.Jproteome.8B00745 |
0.343 |
|
| 2018 |
Lundquist MR, Goncalves MD, Loughran RM, Possik E, Vijayaraghavan T, Yang A, Pauli C, Ravi A, Verma A, Yang Z, Johnson JL, Wong JCY, Ma Y, Hwang KS, Weinkove D, ... Divecha N, et al. Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy. Molecular Cell. 70: 531-544.e9. PMID 29727621 DOI: 10.1016/J.Molcel.2018.03.037 |
0.431 |
|
| 2016 |
Fiume R, Jones DR, Divecha N. PIP4K2B: Coupling GTP Sensing to PtdIns5P Levels to Regulate Tumorigenesis. Trends in Biochemical Sciences. PMID 27132569 DOI: 10.1016/J.Tibs.2016.04.003 |
0.353 |
|
| 2016 |
Divecha N. Phosphoinositides in the nucleus and myogenic differentiation: how a nuclear turtle with a PHD builds muscle. Biochemical Society Transactions. 44: 299-306. PMID 26862219 DOI: 10.1042/Bst20150238 |
0.365 |
|
| 2015 |
Stijf-Bultsma Y, Sommer L, Tauber M, Baalbaki M, Giardoglou P, Jones DR, Gelato KA, van Pelt J, Shah Z, Rahnamoun H, Toma C, Anderson KE, Hawkins P, Lauberth SM, Haramis AP, ... ... Divecha N, et al. The basal transcription complex component TAF3 transduces changes in nuclear phosphoinositides into transcriptional output. Molecular Cell. 58: 453-67. PMID 25866244 DOI: 10.1016/J.Molcel.2015.03.009 |
0.408 |
|
| 2015 |
Fiume R, Stijf-Bultsma Y, Shah ZH, Keune WJ, Jones DR, Jude JG, Divecha N. PIP4K and the role of nuclear phosphoinositides in tumour suppression. Biochimica Et Biophysica Acta. 1851: 898-910. PMID 25728392 DOI: 10.1016/J.Bbalip.2015.02.014 |
0.45 |
|
| 2015 |
Jude JG, Spencer GJ, Huang X, Somerville TD, Jones DR, Divecha N, Somervaille TC. A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival. Oncogene. 34: 1253-62. PMID 24681948 DOI: 10.1038/Onc.2014.77 |
0.446 |
|
| 2015 |
Fiume R, Jan Keune W, Faenza I, Bultsma Y, Ramazzotti G, Jones DR, Martelli AM, Somner L, Follo MY, Divecha N, Cocco L. Nuclear phosphoinositides:Location, regulation and function Sub-Cellular Biochemistry. 59: 335-361. PMID 22374096 DOI: 10.1007/978-94-007-3015-1_11 |
0.395 |
|
| 2014 |
Jones DR, Keune WJ, Anderson KE, Stephens LR, Hawkins PT, Divecha N. The hexosamine biosynthesis pathway and O-GlcNAcylation maintain insulin-stimulated PI3K-PKB phosphorylation and tumour cell growth after short-term glucose deprivation. The Febs Journal. 281: 3591-608. PMID 24938479 DOI: 10.1111/Febs.12879 |
0.353 |
|
| 2014 |
Gelato KA, Tauber M, Ong MS, Winter S, Hiragami-Hamada K, Sindlinger J, Lemak A, Bultsma Y, Houliston S, Schwarzer D, Divecha N, Arrowsmith CH, Fischle W. Accessibility of different histone H3-binding domains of UHRF1 is allosterically regulated by phosphatidylinositol 5-phosphate. Molecular Cell. 54: 905-19. PMID 24813945 DOI: 10.1016/J.Molcel.2014.04.004 |
0.308 |
|
| 2014 |
Fiume R, Huang X, Ramazzotti G, Mongiorgi S, Santi P, Somervaille T, Divecha N. Phospholipase c beta 1 (PLCb1) in acute myeloid leukemia (AML): a novel potential therapeutic target Italian Journal of Anatomy and Embryology. 119: 88. DOI: 10.13128/Ijae-15925 |
0.365 |
|
| 2013 |
Keune WJ, Sims AH, Jones DR, Bultsma Y, Lynch JT, Jirström K, Landberg G, Divecha N. Low PIP4K2B expression in human breast tumors correlates with reduced patient survival: A role for PIP4K2B in the regulation of E-cadherin expression. Cancer Research. 73: 6913-25. PMID 24127122 DOI: 10.1158/0008-5472.Can-13-0424 |
0.3 |
|
| 2013 |
Shah ZH, Jones DR, Sommer L, Foulger R, Bultsma Y, D'Santos C, Divecha N. Nuclear phosphoinositides and their impact on nuclear functions. The Febs Journal. 280: 6295-310. PMID 24112514 DOI: 10.1111/Febs.12543 |
0.436 |
|
| 2013 |
van den Bout I, Jones DR, Shah ZH, Halstead JR, Keune WJ, Mohammed S, D'Santos CS, Divecha N. Collaboration of AMPK and PKC to induce phosphorylation of Ser413 on PIP5K1B resulting in decreased kinase activity and reduced PtdIns(4,5)P2 synthesis in response to oxidative stress and energy restriction. The Biochemical Journal. 455: 347-58. PMID 23909401 DOI: 10.1042/Bj20130259 |
0.465 |
|
| 2013 |
Jones DR, Ramirez IB, Lowe M, Divecha N. Measurement of phosphoinositides in the zebrafish Danio rerio. Nature Protocols. 8: 1058-72. PMID 23660755 DOI: 10.1038/Nprot.2013.040 |
0.373 |
|
| 2013 |
Keune WJ, Jones DR, Divecha N. PtdIns5P and Pin1 in oxidative stress signaling. Advances in Biological Regulation. 53: 179-89. PMID 23602596 DOI: 10.1016/J.Jbior.2013.02.001 |
0.425 |
|
| 2013 |
Elouarrat D, van der Velden YU, Jones DR, Moolenaar WH, Divecha N, Haramis AP. Role of phosphatidylinositol 5-phosphate 4-kinase α in zebrafish development. The International Journal of Biochemistry & Cell Biology. 45: 1293-301. PMID 23542014 DOI: 10.1016/J.Biocel.2013.03.009 |
0.573 |
|
| 2013 |
Gupta A, Toscano S, Trivedi D, Jones DR, Mathre S, Clarke JH, Divecha N, Raghu P. Phosphatidylinositol 5-phosphate 4-kinase (PIP4K) regulates TOR signaling and cell growth during Drosophila development. Proceedings of the National Academy of Sciences of the United States of America. 110: 5963-8. PMID 23530222 DOI: 10.1073/Pnas.1219333110 |
0.44 |
|
| 2013 |
Jones DR, Foulger R, Keune WJ, Bultsma Y, Divecha N. PtdIns5P is an oxidative stress-induced second messenger that regulates PKB activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 1644-56. PMID 23241309 DOI: 10.1096/Fj.12-218842 |
0.416 |
|
| 2012 |
Lekomtsev S, Su KC, Pye VE, Blight K, Sundaramoorthy S, Takaki T, Collinson LM, Cherepanov P, Divecha N, Petronczki M. Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis. Nature. 492: 276-9. PMID 23235882 DOI: 10.1038/Nature11773 |
0.338 |
|
| 2012 |
Keune WJ, Jones DR, Bultsma Y, Sommer L, Zhou XZ, Lu KP, Divecha N. Regulation of phosphatidylinositol-5-phosphate signaling by Pin1 determines sensitivity to oxidative stress. Science Signaling. 5: ra86. PMID 23193159 DOI: 10.1126/Scisignal.2003223 |
0.379 |
|
| 2012 |
van Baal J, de Widt J, Divecha N, van Blitterswijk WJ. Diacylglycerol kinase θ counteracts protein kinase C-mediated inactivation of the EGF receptor. The International Journal of Biochemistry & Cell Biology. 44: 1791-9. PMID 22732145 DOI: 10.1016/J.Biocel.2012.06.021 |
0.408 |
|
| 2012 |
Ding Y, Ndamukong I, Zhao Y, Xia Y, Riethoven JJ, Jones DR, Divecha N, Avramova Z. Divergent functions of the myotubularin (MTM) homologs AtMTM1 and AtMTM2 in Arabidopsis thaliana: evolution of the plant MTM family. The Plant Journal : For Cell and Molecular Biology. 70: 866-78. PMID 22324391 DOI: 10.1111/J.1365-313X.2012.04936.X |
0.338 |
|
| 2011 |
Alderliesten MC, Klarenbeek JB, van der Luit AH, van Lummel M, Jones DR, Zerp S, Divecha N, Verheij M, van Blitterswijk WJ. Phosphoinositide phosphatase SHIP-1 regulates apoptosis induced by edelfosine, Fas ligation and DNA damage in mouse lymphoma cells. The Biochemical Journal. 440: 127-35. PMID 21793801 DOI: 10.1042/Bj20110125 |
0.393 |
|
| 2011 |
Lewis AE, Sommer L, Arntzen MØ, Strahm Y, Morrice NA, Divecha N, D'Santos CS. Identification of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins by neomycin extraction. Molecular & Cellular Proteomics : McP. 10: M110.003376. PMID 21048195 DOI: 10.1074/Mcp.M110.003376 |
0.438 |
|
| 2011 |
Blaser J, Nussbaum RL, Divecha N, Somervaille T. A Targeted shRNA Knockdown Screen of Phosphoinositide Modulator Genes Reveals INPP5B As Required for Cell Cycle Progression of MLL-AF9 Acute Myeloid Leukemia Cells Blood. 118: 2444-2444. DOI: 10.1182/Blood.V118.21.2444.2444 |
0.43 |
|
| 2010 |
Ndamukong I, Jones DR, Lapko H, Divecha N, Avramova Z. Phosphatidylinositol 5-phosphate links dehydration stress to the activity of ARABIDOPSIS TRITHORAX-LIKE factor ATX1. Plos One. 5: e13396. PMID 20967218 DOI: 10.1371/Journal.Pone.0013396 |
0.339 |
|
| 2010 |
Halstead JR, Savaskan NE, van den Bout I, Van Horck F, Hajdo-Milasinovic A, Snell M, Keune WJ, Ten Klooster JP, Hordijk PL, Divecha N. Rac controls PIP5K localisation and PtdIns(4,5)Pâ‚‚ synthesis, which modulates vinculin localisation and neurite dynamics. Journal of Cell Science. 123: 3535-46. PMID 20841379 DOI: 10.1242/Jcs.062679 |
0.628 |
|
| 2010 |
Divecha N. Methods to assess changes in the pattern of nuclear phosphoinositides. Methods in Molecular Biology (Clifton, N.J.). 645: 165-77. PMID 20645188 DOI: 10.1007/978-1-60327-175-2_11 |
0.448 |
|
| 2010 |
Bultsma Y, Keune WJ, Divecha N. PIP4Kbeta interacts with and modulates nuclear localization of the high-activity PtdIns5P-4-kinase isoform PIP4Kalpha. The Biochemical Journal. 430: 223-35. PMID 20583997 DOI: 10.1042/Bj20100341 |
0.421 |
|
| 2010 |
Divecha N. Lipid kinases: charging PtdIns(4,5)P2 synthesis. Current Biology : Cb. 20: R154-7. PMID 20178759 DOI: 10.1016/J.Cub.2010.01.016 |
0.363 |
|
| 2009 |
van den Bout I, Divecha N. PIP5K-driven PtdIns(4,5)P2 synthesis: regulation and cellular functions. Journal of Cell Science. 122: 3837-50. PMID 19889969 DOI: 10.1242/Jcs.056127 |
0.429 |
|
| 2009 |
Halstead JR, Snel MH, Meeuws S, Jones DR, Divecha N. Assaying endogenous phosphatidylinositol-4-phosphate 5-kinase (PIP5K) activities. Methods in Molecular Biology (Clifton, N.J.). 462: 391-402. PMID 19160683 DOI: 10.1007/978-1-60327-115-8_25 |
0.478 |
|
| 2009 |
Jones DR, Bultsma Y, Keune WJ, Divecha N. Methods for the determination of the mass of nuclear PtdIns4P, PtdIns5P, and PtdIns(4,5)P2. Methods in Molecular Biology (Clifton, N.J.). 462: 75-88. PMID 19160662 DOI: 10.1007/978-1-60327-115-8_5 |
0.441 |
|
| 2008 |
Panbianco C, Weinkove D, Zanin E, Jones D, Divecha N, Gotta M, Ahringer J. A casein kinase 1 and PAR proteins regulate asymmetry of a PIP(2) synthesis enzyme for asymmetric spindle positioning. Developmental Cell. 15: 198-208. PMID 18694560 DOI: 10.1016/J.Devcel.2008.06.002 |
0.412 |
|
| 2008 |
Los AP, de Widt J, van Blitterswijk WJ, Divecha N. Is there a role for diacylglycerol kinase-zeta in cell cycle regulation? Advances in Enzyme Regulation. 48: 31-9. PMID 18358241 DOI: 10.1016/j.advenzreg.2008.02.001 |
0.347 |
|
| 2007 |
van Zeijl L, Ponsioen B, Giepmans BN, Ariaens A, Postma FR, Várnai P, Balla T, Divecha N, Jalink K, Moolenaar WH. Regulation of connexin43 gap junctional communication by phosphatidylinositol 4,5-bisphosphate. The Journal of Cell Biology. 177: 881-91. PMID 17535964 DOI: 10.1083/Jcb.200610144 |
0.525 |
|
| 2007 |
Los AP, de Widt J, Topham MK, van Blitterswijk WJ, Divecha N. Protein kinase C inhibits binding of diacylglycerol kinase-zeta to the retinoblastoma protein. Biochimica Et Biophysica Acta. 1773: 352-7. PMID 17239975 DOI: 10.1016/J.Bbamcr.2006.12.004 |
0.324 |
|
| 2007 |
Guillou H, Lécureuil C, Anderson KE, Suire S, Ferguson GJ, Ellson CD, Gray A, Divecha N, Hawkins PT, Stephens LR. Use of the GRP1 PH domain as a tool to measure the relative levels of PtdIns(3,4,5)P3 through a protein-lipid overlay approach. Journal of Lipid Research. 48: 726-32. PMID 17130283 DOI: 10.1194/Jlr.D600038-Jlr200 |
0.347 |
|
| 2006 |
Halstead JR, van Rheenen J, Snel MH, Meeuws S, Mohammed S, D'Santos CS, Heck AJ, Jalink K, Divecha N. A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis. Current Biology : Cb. 16: 1850-6. PMID 16979564 DOI: 10.1016/j.cub.2006.07.066 |
0.323 |
|
| 2006 |
Jones DR, Bultsma Y, Keune WJ, Halstead JR, Elouarrat D, Mohammed S, Heck AJ, D'Santos CS, Divecha N. Nuclear PtdIns5P as a transducer of stress signaling: an in vivo role for PIP4Kbeta. Molecular Cell. 23: 685-95. PMID 16949365 DOI: 10.1016/j.molcel.2006.07.014 |
0.362 |
|
| 2006 |
Los AP, Vinke FP, de Widt J, Topham MK, van Blitterswijk WJ, Divecha N. The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta. The Journal of Biological Chemistry. 281: 858-66. PMID 16286473 DOI: 10.1074/Jbc.M502693200 |
0.393 |
|
| 2005 |
van Baal J, de Widt J, Divecha N, van Blitterswijk WJ. Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C. The Journal of Biological Chemistry. 280: 9870-8. PMID 15632189 DOI: 10.1074/jbc.M409301200 |
0.356 |
|
| 2004 |
Jones DR, Divecha N. Linking lipids to chromatin. Current Opinion in Genetics & Development. 14: 196-202. PMID 15196467 DOI: 10.1016/j.gde.2004.02.003 |
0.308 |
|
| 2002 |
Divecha N, Roefs M, Los A, Halstead J, Bannister A, D'Santos C. Type I PIPkinases interact with and are regulated by the retinoblastoma susceptibility gene product-pRB. Current Biology : Cb. 12: 582-7. PMID 11937028 |
0.35 |
|
| 2002 |
van Horck FP, Lavazais E, Eickholt BJ, Moolenaar WH, Divecha N. Essential role of type I(alpha) phosphatidylinositol 4-phosphate 5-kinase in neurite remodeling. Current Biology : Cb. 12: 241-5. PMID 11839279 DOI: 10.1016/S0960-9822(01)00660-1 |
0.59 |
|
| 2002 |
Meijer HJ, Berrie CP, Iurisci C, Divecha N, Musgrave A, Munnik T. Identification of a new polyphosphoinositide in plants, phosphatidylinositol 5-monophosphate (PtdIns5P), and its accumulation upon osmotic stress. The Biochemical Journal. 360: 491-8. PMID 11716778 DOI: 10.1042/0264-6021:3600491 |
0.312 |
|
| 2001 |
Halstead JR, Roefs M, Ellson CD, D'Andrea S, Chen C, D'Santos CS, Divecha N. A novel pathway of cellular phosphatidylinositol(3,4,5)-trisphosphate synthesis is regulated by oxidative stress. Current Biology : Cb. 11: 386-95. PMID 11301249 DOI: 10.1016/S0960-9822(01)00121-X |
0.369 |
|
| 2001 |
CLARKE JH, LETCHER AJ, D'SANTOS CS, HALSTEAD JR, IRVINE RF, DIVECHA N. Inositol lipids are regulated during cell cycle progression in the nuclei of murine erythroleukaemia cells Biochemical Journal. 357: 905-910. DOI: 10.1042/BJ3570905 |
0.35 |
|
| 2000 |
Divecha N, Roefs M, Halstead JR, D'Andrea S, Fernandez-Borga M, Oomen L, Saqib KM, Wakelam MJ, D'Santos C. Interaction of the type Ialpha PIPkinase with phospholipase D: a role for the local generation of phosphatidylinositol 4, 5-bisphosphate in the regulation of PLD2 activity. The Embo Journal. 19: 5440-9. PMID 11032811 DOI: 10.1093/emboj/19.20.5440 |
0.372 |
|
| 2000 |
Divecha N, Clarke JH, Roefs M, Halstead JR, D'Santos C. Nuclear inositides: inconsistent consistencies. Cellular and Molecular Life Sciences : Cmls. 57: 379-93. PMID 10823239 DOI: 10.1007/PL00000700 |
0.336 |
|
| 2000 |
Hinchliffe KA, Ciruela A, Letcher AJ, Divecha N, Irvine RF. Regulation of type IIalpha phosphatidylinositol phosphate kinase localisation by the protein kinase CK2. Current Biology : Cb. 9: 983-6. PMID 10508590 DOI: 10.1016/S0960-9822(99)80429-1 |
0.33 |
|
| 1999 |
D'Santos CS, Clarke JH, Irvine RF, Divecha N. Nuclei contain two differentially regulated pools of diacylglycerol. Current Biology : Cb. 9: 437-40. PMID 10226027 DOI: 10.1016/S0960-9822(99)80193-6 |
0.463 |
|
| 1993 |
Banfić H, Vuica M, Knotek M, Moslavac S, Divecha N. Inositol lipid signalling occurs in brush-border membranes during initiation of compensatory renal growth in the rat. The Biochemical Journal. 599-605. PMID 8240263 DOI: 10.1042/Bj2950599 |
0.337 |
|
| 1992 |
Irvine RF, Divecha N. Phospholipids in the nucleus--metabolism and possible functions. Seminars in Cell Biology. 3: 225-35. PMID 1330068 DOI: 10.1016/1043-4682(92)90024-P |
0.383 |
|
| 1990 |
Divecha N. Regulation of cell growth and activation, Vol. 1 Trends in Biochemical Sciences. 15: 403. DOI: 10.1016/0968-0004(90)90248-A |
0.357 |
|
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