| Year |
Citation |
Score |
| 2023 |
Arbour CA, Vuksanovic N, Bernstein HM, Allen KN, Imperiali B. Characterization of PglJ, a Glycosyltransferase in the N-Linked Protein Glycosylation Pathway that Expands Glycan Diversity. Biochemistry. PMID 38110367 DOI: 10.1021/acs.biochem.3c00564 |
0.815 |
|
| 2023 |
Vuksanovic N, Clasman JR, Imperiali B, Allen KN. Specificity determinants revealed by the structure of glycosyltransferase Campylobacter concisus PglA. Protein Science : a Publication of the Protein Society. PMID 38019455 DOI: 10.1002/pro.4848 |
0.84 |
|
| 2023 |
Majumder A, Vuksanovic N, Ray LC, Bernstein HM, Allen KN, Imperiali B, Straub JE. Synergistic computational and experimental studies of a phosphoglycosyl transferase membrane/ligand ensemble. The Journal of Biological Chemistry. 105194. PMID 37633332 DOI: 10.1016/j.jbc.2023.105194 |
0.82 |
|
| 2023 |
Anderson AJ, Dodge GJ, Allen KN, Imperiali B. Co-conserved sequence motifs are predictive of substrate specificity in a family of monotopic phosphoglycosyl transferases. Protein Science : a Publication of the Protein Society. e4646. PMID 37096962 DOI: 10.1002/pro.4646 |
0.598 |
|
| 2023 |
Muellers SN, Tararina MA, Kuzmanovic U, Galagan JE, Allen KN. Structural Insights into the Substrate Range of a Bacterial Monoamine Oxidase. Biochemistry. PMID 36662673 DOI: 10.1021/acs.biochem.2c00540 |
0.41 |
|
| 2022 |
Muellers SN, Nyitray MM, Reynarowych N, Saljanin E, Benzie AL, Schoenfeld AR, Stockman BJ, Allen KN. Structure-Guided Insight into the Specificity and Mechanism of a Parasitic Nucleoside Hydrolase. Biochemistry. PMID 35994320 DOI: 10.1021/acs.biochem.2c00361 |
0.424 |
|
| 2021 |
Turner LD, Nielsen AL, Lin L, Campedelli AJ, Silvaggi NR, Chen JS, Wakefield AE, Allen KN, Janda KD. Use of Crystallography and Molecular Modeling for the Inhibition of the Botulinum Neurotoxin A Protease. Acs Medicinal Chemistry Letters. 12: 1318-1324. PMID 34413962 DOI: 10.1021/acsmedchemlett.1c00325 |
0.713 |
|
| 2021 |
O'Toole KH, Bernstein HM, Allen KN, Imperiali B. The surprising structural and mechanistic dichotomy of membrane-associated phosphoglycosyl transferases. Biochemical Society Transactions. PMID 34100892 DOI: 10.1042/BST20200762 |
0.552 |
|
| 2021 |
O'Toole KH, Imperiali B, Allen KN. Glycoconjugate pathway connections revealed by sequence similarity network analysis of the monotopic phosphoglycosyl transferases. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33472976 DOI: 10.1073/pnas.2018289118 |
0.544 |
|
| 2020 |
Lin L, Olson ME, Sugane T, Turner LD, Tararina MA, Nielsen AL, Kurbanov EK, Pellett S, Johnson EA, Cohen SM, Allen KN, Janda KD. A Catch and Anchor Approach to Combat both Toxicity and Longevity of Botulinum Toxin A. Journal of Medicinal Chemistry. PMID 32886509 DOI: 10.1021/Acs.Jmedchem.0C01006 |
0.378 |
|
| 2020 |
Harvey C, O'Toole K, Liu C, Mariano PS, Dunaway-Mariano D, Allen KN. Structural Analysis of Binding Determinants of Trehalose-6-phosphate Phosphatase using Ground-State Complexes. Biochemistry. PMID 32786412 DOI: 10.1021/Acs.Biochem.0C00317 |
0.506 |
|
| 2020 |
Tararina MA, Allen KN. Bioinformatic Analysis of the Flavin-Dependent Amine Oxidase Superfamily: Adaptations for Substrate Specificity and Catalytic Diversity. Journal of Molecular Biology. PMID 32198115 DOI: 10.1016/J.Jmb.2020.03.007 |
0.495 |
|
| 2020 |
Victor T, O'Toole K, Easthon LM, Ge M, Smith RJ, Huang X, Yan H, Chu YS, Chen S, Gursoy D, Ralle M, Imperiali B, Allen KN, Miller LM. Lanthanide-Binding Tags for 3D X-Ray Imaging of Proteins in Cells at Nanoscale Resolution. Journal of the American Chemical Society. PMID 31923358 DOI: 10.1021/Jacs.9B11571 |
0.56 |
|
| 2020 |
Pyeatt G, Muellers S, Whitty A, Allen KN. Structural Characterization of the Covalent Binding of Keap1 and Thiol‐containing Small Molecules The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07357 |
0.391 |
|
| 2020 |
Dodge G, O’Toole K, Bernstein H, Seebald L, Allen KN, Imperiali B. Structural and Functional Characterization of Phosphoglycosyl Transferases from Human Pathogens The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05269 |
0.543 |
|
| 2019 |
Zhong M, Lynch AJ, Muellers SN, Jehle S, Luo L, Hall DR, Iwase R, Carolan JP, Egbert M, Wakefield A, Streu K, Harvey CM, Ortet PC, Kozakov D, Vajda S, ... Allen KN, et al. Interaction Energetics and Druggability of the Protein-Protein Interaction between Kelch-like ECH-associated Protein 1 (KEAP1) and Nuclear Factor, Erythroid 2 Like 2 (Nrf2). Biochemistry. PMID 31851823 DOI: 10.1021/Acs.Biochem.9B00943 |
0.778 |
|
| 2019 |
Shaffer R, DeMaria AH, Kagermazova L, Liu Y, Babaei M, Penix S, Cervantes A, Jehle S, Makowski L, Gilmore TD, Whitty A, Allen KN. A Central Region of NEMO is Required for IKKβ-Induced Conformational Change and for Signal Propagation. Biochemistry. PMID 31145594 DOI: 10.1021/Acs.Biochem.8B01316 |
0.374 |
|
| 2019 |
Allen KN, Imperiali B. Structural and mechanistic themes in glycoconjugate biosynthesis at membrane interfaces. Current Opinion in Structural Biology. 59: 81-90. PMID 31003021 DOI: 10.1016/J.Sbi.2019.03.013 |
0.631 |
|
| 2018 |
Allen KN, Entova S, Ray LC, Imperiali B. Monotopic Membrane Proteins Join the Fold. Trends in Biochemical Sciences. PMID 30337134 DOI: 10.1016/J.Tibs.2018.09.013 |
0.567 |
|
| 2018 |
Harvey CM, O'Toole KH, Allen KN. Crystallization of Liganded Phosphatases in the HAD Superfamily. Methods in Enzymology. 607: 157-184. PMID 30149857 DOI: 10.1016/Bs.Mie.2018.06.011 |
0.495 |
|
| 2018 |
Zhang C, Allen KN, Dunaway-Mariano D. Mechanism of Substrate Recognition and Catalysis of the Haloalkanoic Acid Dehalogenase Family Member, α-Phosphoglucomutase. Biochemistry. PMID 29952545 DOI: 10.1021/Acs.Biochem.8B00396 |
0.422 |
|
| 2018 |
Tararina MA, Xue S, Smith LC, Muellers SN, Miranda PO, Janda KD, Allen KN. Crystallography Coupled with Kinetic Analysis Provide Mechanistic Underpinnings of a Nicotine-Degrading Enzyme. Biochemistry. PMID 29812904 DOI: 10.1021/Acs.Biochem.8B00384 |
0.466 |
|
| 2018 |
Ray LC, Das D, Entova S, Lukose V, Lynch AJ, Imperiali B, Allen KN. Membrane association of monotopic phosphoglycosyl transferase underpins function. Nature Chemical Biology. PMID 29769739 DOI: 10.1038/S41589-018-0054-Z |
0.579 |
|
| 2018 |
Ji T, Zhang C, Zheng L, Dunaway-Mariano D, Allen KN. The structural basis of the molecular switch between phosphatase and mutase functions of human phosphomannomutase 1 under ischemic conditions. Biochemistry. PMID 29695157 DOI: 10.1021/Acs.Biochem.8B00223 |
0.54 |
|
| 2018 |
Beglov D, Hall DR, Wakefield AE, Luo L, Allen KN, Kozakov D, Whitty A, Vajda S. Exploring the structural origins of cryptic sites on proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581267 DOI: 10.1073/Pnas.1711490115 |
0.452 |
|
| 2017 |
Latham JA, Ji T, Matthews K, Mariano P, Allen KN, Dunaway-Mariano D. The Hotdog-fold Thioesterase PA1618 Catalytic Mechanism Revealed by X-ray Structure Determination of the Substrate Oxygen Ester Analog Complex. Chembiochem : a European Journal of Chemical Biology. PMID 28741300 DOI: 10.1002/Cbic.201700322 |
0.536 |
|
| 2017 |
Jacobson AR, Adler M, Silvaggi NR, Allen KN, Smith GM, Fredenburg RA, Stein RL, Park JB, Feng X, Shoemaker CB, Deshpande SS, Goodnough MC, Malizio CJ, Johnson EA, Pellett S, et al. Small molecule metalloprotease inhibitor with in vitro, ex vivo and in vivo efficacy against botulinum neurotoxin serotype A. Toxicon : Official Journal of the International Society On Toxinology. PMID 28698055 DOI: 10.1016/J.Toxicon.2017.06.016 |
0.676 |
|
| 2017 |
Barthelmes D, Barthelmes K, Schnorr K, Jonker HRA, Bodmer B, Allen KN, Imperiali B, Schwalbe H. Conformational dynamics and alignment properties of loop lanthanide-binding-tags (LBTs) studied in interleukin-1β. Journal of Biomolecular Nmr. PMID 28534082 DOI: 10.1007/S10858-017-0118-5 |
0.57 |
|
| 2017 |
Bremer PT, Pellett S, Carolan JP, Tepp WH, Eubanks LM, Allen KN, Johnson EA, Janda KD. Metal Ions Effectively Ablate the Action of Botulinum Neurotoxin A. Journal of the American Chemical Society. PMID 28475321 DOI: 10.1021/Jacs.7B01084 |
0.765 |
|
| 2016 |
Tararina MA, Janda KD, Allen KN. Structural Analysis Provides Mechanistic Insight into Nicotine Oxidoreductase from Pseudomonas putida. Biochemistry. 55: 6595-6598. PMID 27933790 DOI: 10.1021/Acs.Biochem.6B00963 |
0.412 |
|
| 2016 |
Allen KN, Dunaway-Mariano D. Catalytic scaffolds for phosphoryl group transfer. Current Opinion in Structural Biology. 41: 172-179. PMID 27526404 DOI: 10.1016/J.Sbi.2016.07.017 |
0.453 |
|
| 2016 |
Zhu W, Easthon LM, Reinhardt LA, Tu C, Cohen SE, Silverman DN, Allen KN, Richards NG. Substrate Binding Mode and Molecular Basis of a Specificity Switch in Oxalate Decarboxylase. Biochemistry. 55: 2163-73. PMID 27014926 DOI: 10.1021/Acs.Biochem.6B00043 |
0.752 |
|
| 2015 |
Lukose V, Luo L, Kozakov D, Vajda S, Allen KN, Imperiali B. Conservation and Covariance in Small Bacterial Phosphoglycosyltransferases Identifies the Functional Catalytic Core. Biochemistry. PMID 26600273 DOI: 10.1021/Acs.Biochem.5B01086 |
0.648 |
|
| 2015 |
Rago F, Saltzberg D, Allen KN, Tolan DR. Enzyme Substrate Specificity Conferred by Distinct Conformational Pathways. Journal of the American Chemical Society. 137: 13876-86. PMID 26440863 DOI: 10.1021/Jacs.5B08149 |
0.804 |
|
| 2015 |
Barthelmes D, Gränz M, Barthelmes K, Allen KN, Imperiali B, Prisner T, Schwalbe H. Encoded loop-lanthanide-binding tags for long-range distance measurements in proteins by NMR and EPR spectroscopy. Journal of Biomolecular Nmr. 63: 275-82. PMID 26341230 DOI: 10.1007/S10858-015-9984-X |
0.58 |
|
| 2015 |
Xia B, Mamonov A, Leysen S, Allen KN, Strelkov SV, Paschalidis ICh, Vajda S, Kozakov D. Accounting for observed small angle X-ray scattering profile in the protein-protein docking server cluspro. Journal of Computational Chemistry. 36: 1568-72. PMID 26095982 DOI: 10.1002/Jcc.23952 |
0.366 |
|
| 2015 |
Kozakov D, Hall DR, Jehle S, Luo L, Ochiana SO, Jones EV, Pollastri M, Allen KN, Whitty A, Vajda S. Ligand deconstruction: Why some fragment binding positions are conserved and others are not. Proceedings of the National Academy of Sciences of the United States of America. 112: E2585-94. PMID 25918377 DOI: 10.1073/Pnas.1501567112 |
0.367 |
|
| 2015 |
Huang H, Pandya C, Liu C, Al-Obaidi NF, Wang M, Zheng L, Toews Keating S, Aono M, Love JD, Evans B, Seidel RD, Hillerich BS, Garforth SJ, Almo SC, Mariano PS, ... ... Allen KN, et al. Panoramic view of a superfamily of phosphatases through substrate profiling. Proceedings of the National Academy of Sciences of the United States of America. 112: E1974-83. PMID 25848029 DOI: 10.1073/Pnas.1423570112 |
0.829 |
|
| 2015 |
London N, Farelli JD, Brown SD, Liu C, Huang H, Korczynska M, Al-Obaidi NF, Babbitt PC, Almo SC, Allen KN, Shoichet BK. Covalent docking predicts substrates for haloalkanoate dehalogenase superfamily phosphatases. Biochemistry. 54: 528-37. PMID 25513739 DOI: 10.1021/Bi501140K |
0.617 |
|
| 2014 |
Zhou L, Yeo AT, Ballarano C, Weber U, Allen KN, Gilmore TD, Whitty A. Disulfide-mediated stabilization of the IκB kinase binding domain of NF-κB essential modulator (NEMO). Biochemistry. 53: 7929-44. PMID 25400026 DOI: 10.1021/Bi500920N |
0.452 |
|
| 2014 |
Pandya C, Farelli JD, Dunaway-Mariano D, Allen KN. Enzyme promiscuity: engine of evolutionary innovation. The Journal of Biological Chemistry. 289: 30229-36. PMID 25210039 DOI: 10.1074/Jbc.R114.572990 |
0.817 |
|
| 2014 |
Wu R, Latham JA, Chen D, Farelli J, Zhao H, Matthews K, Allen KN, Dunaway-Mariano D. Structure and catalysis in the Escherichia coli hotdog-fold thioesterase paralogs YdiI and YbdB. Biochemistry. 53: 4788-805. PMID 25010423 DOI: 10.1021/Bi500334V |
0.562 |
|
| 2014 |
Latham JA, Chen D, Allen KN, Dunaway-Mariano D. Divergence of substrate specificity and function in the Escherichia coli hotdog-fold thioesterase paralogs YdiI and YbdB. Biochemistry. 53: 4775-87. PMID 24992697 DOI: 10.1021/Bi500333M |
0.427 |
|
| 2014 |
Farelli JD, Galvin BD, Li Z, Liu C, Aono M, Garland M, Hallett OE, Causey TB, Ali-Reynolds A, Saltzberg DJ, Carlow CK, Dunaway-Mariano D, Allen KN. Structure of the trehalose-6-phosphate phosphatase from Brugia malayi reveals key design principles for anthelmintic drugs. Plos Pathogens. 10: e1004245. PMID 24992307 DOI: 10.1371/Journal.Ppat.1004245 |
0.833 |
|
| 2014 |
Barelier S, Cummings JA, Rauwerdink AM, Hitchcock DS, Farelli JD, Almo SC, Raushel FM, Allen KN, Shoichet BK. Substrate deconstruction and the nonadditivity of enzyme recognition. Journal of the American Chemical Society. 136: 7374-82. PMID 24791931 DOI: 10.1021/Ja501354Q |
0.639 |
|
| 2014 |
Pandya C, Dunaway-Mariano D, Xia Y, Allen KN. Structure-guided approach for detecting large domain inserts in protein sequences as illustrated using the haloacid dehalogenase superfamily. Proteins. 82: 1896-906. PMID 24577717 DOI: 10.1002/Prot.24543 |
0.798 |
|
| 2014 |
Campomanes P, Kellett WF, Easthon LM, Ozarowski A, Allen KN, Angerhofer A, Rothlisberger U, Richards NG. Assigning the EPR fine structure parameters of the Mn(II) centers in Bacillus subtilis oxalate decarboxylase by site-directed mutagenesis and DFT/MM calculations. Journal of the American Chemical Society. 136: 2313-23. PMID 24444454 DOI: 10.1021/Ja408138F |
0.356 |
|
| 2013 |
Cote SM, Gilmore TD, Shaffer R, Weber U, Bollam R, Golden MS, Glover K, Herscovitch M, Ennis T, Allen KN, Whitty A. Mutation of nonessential cysteines shows that the NF-κB essential modulator forms a constitutive noncovalent dimer that binds IκB kinase-β with high affinity. Biochemistry. 52: 9141-54. PMID 24266532 DOI: 10.1021/Bi401368R |
0.417 |
|
| 2013 |
Bryan T, González JM, Bacik JP, DeNunzio NJ, Unkefer CJ, Schrader TE, Ostermann A, Dunaway-Mariano D, Allen KN, Fisher SZ. Neutron diffraction studies towards deciphering the protonation state of catalytic residues in the bacterial KDN9P phosphatase. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 69: 1015-9. PMID 23989152 DOI: 10.1107/S1744309113021386 |
0.767 |
|
| 2013 |
Pandya C, Brown S, Pieper U, Sali A, Dunaway-Mariano D, Babbitt PC, Xia Y, Allen KN. Consequences of domain insertion on sequence-structure divergence in a superfold. Proceedings of the National Academy of Sciences of the United States of America. 110: E3381-7. PMID 23959887 DOI: 10.1073/Pnas.1305519110 |
0.796 |
|
| 2013 |
Wang M, Song F, Wu R, Allen KN, Mariano PS, Dunaway-Mariano D. Co-evolution of HAD phosphatase and hotdog-fold thioesterase domain function in the menaquinone-pathway fusion proteins BF1314 and PG1653. Febs Letters. 587: 2851-9. PMID 23851007 DOI: 10.1016/J.Febslet.2013.07.009 |
0.367 |
|
| 2013 |
Daughtry KD, Huang H, Malashkevich V, Patskovsky Y, Liu W, Ramagopal U, Sauder JM, Burley SK, Almo SC, Dunaway-Mariano D, Allen KN. Structural basis for the divergence of substrate specificity and biological function within HAD phosphatases in lipopolysaccharide and sialic acid biosynthesis. Biochemistry. 52: 5372-86. PMID 23848398 DOI: 10.1021/Bi400659K |
0.833 |
|
| 2013 |
Šilhár P, Silvaggi NR, Pellett S, Čapková K, Johnson EA, Allen KN, Janda KD. Evaluation of adamantane hydroxamates as botulinum neurotoxin inhibitors: synthesis, crystallography, modeling, kinetic and cellular based studies. Bioorganic & Medicinal Chemistry. 21: 1344-8. PMID 23340139 DOI: 10.1016/J.Bmc.2012.12.001 |
0.689 |
|
| 2012 |
Daughtry KD, Martin LJ, Sarraju A, Imperiali B, Allen KN. Tailoring encodable lanthanide-binding tags as MRI contrast agents. Chembiochem : a European Journal of Chemical Biology. 13: 2567-74. PMID 23150430 DOI: 10.1002/Cbic.201200448 |
0.799 |
|
| 2012 |
Saylor BT, Reinhardt LA, Lu Z, Shukla MS, Nguyen L, Cleland WW, Angerhofer A, Allen KN, Richards NG. A structural element that facilitates proton-coupled electron transfer in oxalate decarboxylase. Biochemistry. 51: 2911-20. PMID 22404040 DOI: 10.1021/Bi300001Q |
0.435 |
|
| 2012 |
Daughtry KD, Xiao Y, Stoner-Ma D, Cho E, Orville AM, Liu P, Allen KN. Quaternary ammonium oxidative demethylation: X-ray crystallographic, resonance raman, and uv-visible spectroscopic analysis of a Rieske-type demethylase Journal of the American Chemical Society. 134: 2823-2834. PMID 22224443 DOI: 10.1021/Ja2111898 |
0.784 |
|
| 2011 |
Gerlt JA, Allen KN, Almo SC, Armstrong RN, Babbitt PC, Cronan JE, Dunaway-Mariano D, Imker HJ, Jacobson MP, Minor W, Poulter CD, Raushel FM, Sali A, Shoichet BK, Sweedler JV. The Enzyme Function Initiative. Biochemistry. 50: 9950-62. PMID 21999478 DOI: 10.1021/Bi201312U |
0.581 |
|
| 2011 |
Toteva MM, Silvaggi NR, Allen KN, Richard JP. Binding energy and catalysis by d -xylose isomerase: Kinetic, product, and X-ray Crystallographic analysis of enzyme-catalyzed isomerization of (R)-glyceraldehyde Biochemistry. 50: 10170-10181. PMID 21995300 DOI: 10.1021/Bi201378C |
0.703 |
|
| 2011 |
Lu Z, Dunaway-Mariano D, Allen KN. The X-ray crystallographic structure and specificity profile of HAD superfamily phosphohydrolase BT1666: Comparison of paralogous functions in B. thetaiotaomicron Proteins: Structure, Function and Bioinformatics. 79: 3099-3107. PMID 21989931 DOI: 10.1002/Prot.23137 |
0.492 |
|
| 2011 |
Huang H, Patskovsky Y, Toro R, Farelli JD, Pandya C, Almo SC, Allen KN, Dunaway-Mariano D. Divergence of structure and function in the haloacid dehalogenase enzyme superfamily: Bacteroides thetaiotaomicron BT2127 is an inorganic pyrophosphatase. Biochemistry. 50: 8937-49. PMID 21894910 DOI: 10.1021/Bi201181Q |
0.844 |
|
| 2011 |
Wu R, Garland M, Dunaway-Mariano D, Allen KN. Homo sapiens dullard protein phosphatase shows a preference for the insulin-dependent phosphorylation site of lipin1 Biochemistry. 50: 3045-3047. PMID 21413788 DOI: 10.1021/Bi200336B |
0.376 |
|
| 2011 |
Salzameda NT, Eubanks LM, Zakhari JS, Tsuchikama K, DeNunzio NJ, Allen KN, Hixon MS, Janda KD. A cross-over inhibitor of the botulinum neurotoxin light chain B: a natural product implicating an exosite mechanism of action. Chemical Communications (Cambridge, England). 47: 1713-5. PMID 21203627 DOI: 10.1039/C0Cc04078A |
0.72 |
|
| 2011 |
Barthelmes K, Reynolds AM, Peisach E, Jonker HR, DeNunzio NJ, Allen KN, Imperiali B, Schwalbe H. Engineering encodable lanthanide-binding tags into loop regions of proteins. Journal of the American Chemical Society. 133: 808-19. PMID 21182275 DOI: 10.1021/Ja104983T |
0.79 |
|
| 2010 |
Allen KN, Imperiali B. Lanthanide-tagged proteins--an illuminating partnership. Current Opinion in Chemical Biology. 14: 247-54. PMID 20102793 DOI: 10.1016/J.Cbpa.2010.01.004 |
0.592 |
|
| 2010 |
Stowe GN, Silhár P, Hixon MS, Silvaggi NR, Allen KN, Moe ST, Jacobson AR, Barbieri JT, Janda KD. Chirality holds the key for potent inhibition of the botulinum neurotoxin serotype a protease. Organic Letters. 12: 756-9. PMID 20092262 DOI: 10.1021/Ol902820Z |
0.68 |
|
| 2010 |
Wang L, Huang H, Nguyen HH, Allen KN, Mariano PS, Dunaway-Mariano D. Divergence of biochemical function in the HAD superfamily: D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB) Biochemistry. 49: 1072-1081. PMID 20050615 DOI: 10.1021/Bi902018Y |
0.347 |
|
| 2010 |
Nguyen HH, LiangbingWang, Huang H, Peisach E, Dunaway-Mariano D, Allen KN. Structural determinants of substrate recognition in the HAD superfamily member D-glycero-D-manno-heptose-1,7-bisphosphate phosphatase (GmhB) Biochemistry. 49: 1082-1092. PMID 20050614 DOI: 10.1021/Bi902019Q |
0.539 |
|
| 2009 |
Allen KN, Dunaway-Mariano D. Markers of fitness in a successful enzyme superfamily Current Opinion in Structural Biology. 19: 658-665. PMID 19889535 DOI: 10.1016/J.Sbi.2009.09.008 |
0.443 |
|
| 2009 |
Ho MC, Ménétret JF, Tsuruta H, Allen KN. The origin of the electrostatic perturbation in acetoacetate decarboxylase Nature. 459: 393-397. PMID 19458715 DOI: 10.1038/Nature07938 |
0.512 |
|
| 2009 |
Dai J, Finci L, Zhang C, Lahiri S, Zhang G, Peisach E, Allen KN, Dunaway-Mariano D. Analysis of the structural determinants underlying discrimination between substrate and solvent in β-phosphoglucomutase catalysis Biochemistry. 48: 1984-1995. PMID 19154134 DOI: 10.1021/Bi801653R |
0.827 |
|
| 2009 |
Lu Z, Wang L, Dunaway-Mariano D, Allen KN. Structure-function analysis of 2-Keto-3-deoxy-D-glycero-D-galactonononate- 9-phosphate Phosphatase defines specificity elements in type C0 haloalkanoate dehalogenase family members Journal of Biological Chemistry. 284: 1224-1233. PMID 18986982 DOI: 10.1074/Jbc.M807056200 |
0.485 |
|
| 2008 |
Silvaggi NR, Wilson D, Tzipori S, Allen KN. Catalytic features of the botulinum neurotoxin A light chain revealed by high resolution structure of an inhibitory peptide complex Biochemistry. 47: 5736-5745. PMID 18457419 DOI: 10.1021/Bi8001067 |
0.746 |
|
| 2008 |
Sherawat M, Tolan DR, Allen KN. Structure of a rabbit muscle fructose-1,6-bisphosphate aldolase A dimer variant Acta Crystallographica Section D: Biological Crystallography. 64: 543-550. PMID 18453690 DOI: 10.1107/S0907444908004976 |
0.825 |
|
| 2008 |
Lu Z, Dunaway-Mariano D, Allen KN. The catalytic scaffold of the haloalkanoic acid dehalogenase enzyme superfamily acts as a mold for the trigonal bipyramidal transition state Proceedings of the National Academy of Sciences of the United States of America. 105: 5687-5692. PMID 18398008 DOI: 10.1073/Pnas.0710800105 |
0.474 |
|
| 2008 |
Peisach E, Wang L, Burroughs AM, Aravind L, Dunaway-Mariano D, Allen KN. The X-ray crystallographic structure and activity analysis of a Pseudomonas-specific subfamily of the HAD enzyme superfamily evidences a novel biochemical function Proteins: Structure, Function and Genetics. 70: 197-207. PMID 17654544 DOI: 10.1002/Prot.21583 |
0.477 |
|
| 2007 |
Pezza JA, Stopa JD, Brunyak EM, Allen KN, Tolan DR. Thermodynamic analysis shows conformational coupling and dynamics confer substrate specificity in fructose-1,6-bisphosphate aldolase Biochemistry. 46: 13010-13018. PMID 17935305 DOI: 10.1021/Bi700713S |
0.45 |
|
| 2007 |
Allen KN. Form finds function Nature Chemical Biology. 3: 452-453. PMID 17637773 DOI: 10.1038/Nchembio0807-452 |
0.41 |
|
| 2007 |
Silvaggi NR, Boldt GE, Hixon MS, Kennedy JP, Tzipori S, Janda KD, Allen KN. Structures of Clostridium botulinum Neurotoxin Serotype A Light Chain complexed with small-molecule inhibitors highlight active-site flexibility. Chemistry & Biology. 14: 533-42. PMID 17524984 DOI: 10.1016/J.Chembiol.2007.03.014 |
0.746 |
|
| 2007 |
Silvaggi NR, Martin LJ, Schwalbe H, Imperiali B, Allen KN. Double-lanthanide-binding tags for macromolecular crystallographic structure determination. Journal of the American Chemical Society. 129: 7114-20. PMID 17497863 DOI: 10.1021/Ja070481N |
0.777 |
|
| 2007 |
Martin LJ, Hähnke MJ, Nitz M, Wöhnert J, Silvaggi NR, Allen KN, Schwalbe H, Imperiali B. Double-lanthanide-binding tags: design, photophysical properties, and NMR applications. Journal of the American Chemical Society. 129: 7106-13. PMID 17497862 DOI: 10.1021/Ja070480V |
0.786 |
|
| 2007 |
Allen KN. Structural Enzymology in the Haloalkanoic Acid Dehalogenase Superfamily The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A43-B |
0.324 |
|
| 2006 |
Lahiri SD, Zhang G, Dunaway-Mariano D, Allen KN. Diversification of function in the haloacid dehalogenase enzyme superfamily: The role of the cap domain in hydrolytic phosphorus{single bond}carbon bond cleavage Bioorganic Chemistry. 34: 394-409. PMID 17070898 DOI: 10.1016/J.Bioorg.2006.09.007 |
0.762 |
|
| 2006 |
Burroughs AM, Allen KN, Dunaway-Mariano D, Aravind L. Evolutionary Genomics of the HAD Superfamily: Understanding the Structural Adaptations and Catalytic Diversity in a Superfamily of Phosphoesterases and Allied Enzymes Journal of Molecular Biology. 361: 1003-1034. PMID 16889794 DOI: 10.1016/J.Jmb.2006.06.049 |
0.501 |
|
| 2006 |
Choi KH, Lai V, Foster CE, Morris AJ, Tolan DR, Allen KN. New superfamily members identified for Schiff-base enzymes based on verification of catalytically essential residues. Biochemistry. 45: 8546-55. PMID 16834328 DOI: 10.1021/Bi060239D |
0.426 |
|
| 2006 |
Dai J, Wang L, Allen KN, Radstrom P, Dunaway-Mariano D. Conformational cycling in β-phosphoglucomutase catalysis: Reorientation of the β-D-glucose 1,6-(bis)phosphate intermediate Biochemistry. 45: 7818-7824. PMID 16784233 DOI: 10.1021/Bi060136V |
0.439 |
|
| 2006 |
Silvaggi NR, Zhang C, Lu Z, Dai J, Dunaway-Mariano D, Allen KN. The X-ray crystal structures of human α-phosphomannomutase 1 reveal the structural basis of congenital disorder of glycosylation type 1a Journal of Biological Chemistry. 281: 14918-14926. PMID 16540464 DOI: 10.1074/Jbc.M601505200 |
0.729 |
|
| 2006 |
Tremblay LW, Dunaway-Mariano D, Allen KN. Structure and activity analyses of Escherichia coli K-12 NagD provide insight into the evolution of biochemical function in the haloalkanoic acid dehalogenase superfamily Biochemistry. 45: 1183-1193. PMID 16430214 DOI: 10.1021/Bi051842J |
0.828 |
|
| 2005 |
Zhang G, Dai J, Wang L, Dunaway-Mariano D, Tremblay LW, Allen KN. Catalytic cycling in β-phosphoglucomutase: A kinetic and structural analysis Biochemistry. 44: 9404-9416. PMID 15996095 DOI: 10.1021/Bi050558P |
0.797 |
|
| 2005 |
Lu Z, Dunaway-Mariano D, Allen KN. HAD superfamily phosphotransferase substrate diversification: Structure and function analysis of HAD subclass UB sugar phosphatase BT4131 Biochemistry. 44: 8684-8696. PMID 15952775 DOI: 10.1021/Bi050009J |
0.544 |
|
| 2005 |
Tremblay LW, Zhang G, Dai J, Dunaway-Mariano D, Allen KN. Chemical confirmation of a pentavalent phosphorane in complex with β-phosphoglucomutase Journal of the American Chemical Society. 127: 5298-5299. PMID 15826149 DOI: 10.1021/Ja0509073 |
0.801 |
|
| 2005 |
Malay AD, Allen KN, Tolan DR. Structure of the thermolabile mutant aldolase B, A149P: Molecular basis of hereditary fructose intolerance Journal of Molecular Biology. 347: 135-144. PMID 15733923 DOI: 10.1016/J.Jmb.2005.01.008 |
0.423 |
|
| 2005 |
Ali MH, Taylor CM, Grigoryan G, Allen KN, Imperiali B, Keating AE. Design of a heterospecific, tetrameric, 21-residue miniprotein with mixed alpha/beta structure. Structure (London, England : 1993). 13: 225-34. PMID 15698566 DOI: 10.1016/J.Str.2004.12.009 |
0.59 |
|
| 2004 |
Arakaki TL, Pezza JA, Cronin MA, Hopkins CE, Zimmer DB, Tolan DR, Allen KN. Structure of human brain fructose 1,6-(bis)phosphate aldolase: linking isozyme structure with function. Protein Science : a Publication of the Protein Society. 13: 3077-84. PMID 15537755 DOI: 10.1110/Ps.04915904 |
0.462 |
|
| 2004 |
Peisach E, Selengut JD, Dunaway-Mariano D, Allen KN. X-ray crystal structure of the hypothetical phosphotyrosine phosphatase MDP-1 of the haloacid dehalogenase superfamily Biochemistry. 43: 12770-12779. PMID 15461449 DOI: 10.1021/Bi0490688 |
0.539 |
|
| 2004 |
Allen KN, Dunaway-Mariano D. Phosphoryl group transfer: Evolution of a catalytic scaffold Trends in Biochemical Sciences. 29: 495-503. PMID 15337123 DOI: 10.1016/J.Tibs.2004.07.008 |
0.358 |
|
| 2004 |
Ali MH, Peisach E, Allen KN, Imperiali B. X-ray structure analysis of a designed oligomeric miniprotein reveals a discrete quaternary architecture. Proceedings of the National Academy of Sciences of the United States of America. 101: 12183-8. PMID 15302930 DOI: 10.1073/Pnas.0401245101 |
0.62 |
|
| 2004 |
Nitz M, Sherawat M, Franz KJ, Peisach E, Allen KN, Imperiali B. Structural origin of the high affinity of a chemically evolved lanthanide-binding peptide. Angewandte Chemie (International Ed. in English). 43: 3682-5. PMID 15248272 DOI: 10.1002/Anie.200460028 |
0.776 |
|
| 2004 |
Zhang G, Morais MC, Dai J, Zhang W, Dunaway-Mariano D, Allen KN. Investigation of Metal Ion Binding in Phosphonoacetaldehyde Hydrolase Identifies Sequence Markers for Metal-Activated Enzymes of the HAD Enzyme Superfamily Biochemistry. 43: 4990-4997. PMID 15109258 DOI: 10.1021/Bi036309N |
0.748 |
|
| 2004 |
Lahiri SD, Zhang G, Dai J, Dunaway-Mariano D, Allen KN. Analysis of the Substrate Specificity Loop of the HAD Superfamily Cap Domain Biochemistry. 43: 2812-2820. PMID 15005616 DOI: 10.1021/Bi0356810 |
0.757 |
|
| 2004 |
Morais MC, Zhang G, Zhang W, Olsen DB, Dunaway-Mariano D, Allen KN. X-ray Crystallographic and Site-directed Mutagenesis Analysis of the Mechanism of Schiff-base Formation in Phosphonoacetaldehyde Hydrolase Catalysis Journal of Biological Chemistry. 279: 9353-9361. PMID 14670958 DOI: 10.1074/Jbc.M312345200 |
0.741 |
|
| 2003 |
Zhang G, Allen KN, Dunaway-Mariano D. Enzymatic synthesis of radiolabeled phosphonoacetaldehyde Analytical Biochemistry. 322: 233-237. PMID 14596832 DOI: 10.1016/J.Ab.2003.08.016 |
0.407 |
|
| 2003 |
Lahiri SD, Zhang G, Dunaway-Mariano D, Allen KN. The pentacovalent phosphorus intermediate of a phosphoryl transfer reaction Science. 299: 2067-2071. PMID 12637673 DOI: 10.1126/Science.1082710 |
0.735 |
|
| 2003 |
Pezza JA, Choi KH, Berardini TZ, Beernink PT, Allen KN, Tolan DR. Spatial clustering of isozyme-specific residues reveals unlikely determinants of isozyme specificity in fructose-1,6-bisphosphate aldolase Journal of Biological Chemistry. 278: 17307-17313. PMID 12611890 DOI: 10.1074/Jbc.M209185200 |
0.445 |
|
| 2002 |
Lahiri SD, Wang PF, Babbitt PC, McLeish MJ, Kenyon GL, Allen KN. The 2.1 A structure of Torpedo californica creatine kinase complexed with the ADP-Mg(2+)-NO(3)(-)-creatine transition-state analogue complex. Biochemistry. 41: 13861-7. PMID 12437342 DOI: 10.1021/Bi026655P |
0.747 |
|
| 2002 |
Zhang G, Mazurkie AS, Dunaway-Mariano D, Allen KN. Kinetic evidence for a substrate-induced fit in phosphonoacetaldehyde hydrolase catalysis Biochemistry. 41: 13370-13377. PMID 12416981 DOI: 10.1021/Bi026388N |
0.82 |
|
| 2002 |
Lahiri SD, Zhang G, Dunaway-Mariano D, Allen KN. Caught in the act: The structure of phosphorylated β-phosphoglucomutase from Lactococcus lactis Biochemistry. 41: 8351-8359. PMID 12081483 DOI: 10.1021/Bi0202373 |
0.725 |
|
| 2002 |
Hopkins CE, O'Connor PB, Allen KN, Costello CE, Tolan DR. Chemical-modification rescue assessed by mass spectrometry demonstrates that γ-thia-lysine yields the same activity as lysine in aldolase Protein Science. 11: 1591-1599. PMID 12070312 DOI: 10.1110/Ps.3900102 |
0.398 |
|
| 2002 |
Lahiri SD, Zhang G, Radstrom P, Dunaway-Mariano D, Allen KN. Crystallization and preliminary X-ray diffraction studies of β-phosphoglucomutase from Lactococcus lactus Acta Crystallographica Section D: Biological Crystallography. 58: 324-326. PMID 11807265 DOI: 10.1107/S0907444901019989 |
0.688 |
|
| 2001 |
Choi KH, Shi J, Hopkins CE, Tolan DR, Allen KN. Snapshots of catalysis: The structure of fructose-1,6-(bis)phosphate aldolase covalently bound to the substrate dihydroxyacetone phosphate Biochemistry. 40: 13868-13875. PMID 11705376 DOI: 10.1021/Bi0114877 |
0.52 |
|
| 2000 |
Morais MC, Zhang W, Baker AS, Zhang G, Dunaway-Mariano D, Allen KN. The crystal structure of bacillus cereus phosphonoacetaldehyde hydrolase: insight into catalysis of phosphorus bond cleavage and catalytic diversification within the HAD enzyme superfamily. Biochemistry. 39: 10385-96. PMID 10956028 DOI: 10.1021/Bi001171J |
0.766 |
|
| 2000 |
Morais MC, Baker AS, Dunaway-Mariano D, Allen KN. Crystallization and preliminary crystallographic analysis of phosphonoacetaldehyde hydrolase. Acta Crystallographica. Section D, Biological Crystallography. 56: 206-9. PMID 10666607 DOI: 10.1107/S0907444999015899 |
0.673 |
|
| 1999 |
Choi KH, Laursen RA, Allen KN. The 2.1 Å structure of a cysteine protease with proline specificity from ginger rhizome, Zingiber officinale Biochemistry. 38: 11624-11633. PMID 10512617 DOI: 10.1021/Bi990651B |
0.492 |
|
| 1999 |
Choi KH, Mazurkie AS, Morris AJ, Utheza D, Tolan DR, Allen KN. Structure of a fructose-1,6-bis(phosphate) aldolase liganded to its natural substrate in a cleavage-defective mutant at 2.3 Å Biochemistry. 38: 12655-12664. PMID 10504235 DOI: 10.1021/Bi9828371 |
0.835 |
|
| 1996 |
Allen KN, Bellamacina CR, Ding X, Jeffery CJ, Mattos C, Petsko GA, Ringe D. An Experimental Approach to Mapping the Binding Surfaces of Crystalline Proteins† The Journal of Physical Chemistry. 100: 2605-2611. DOI: 10.1021/Jp952516O |
0.788 |
|
| 1995 |
Allen KN, Lavie A, Petsko GA, Ringe D. Design, synthesis, and characterization of a potent xylose isomerase inhibitor, D-threonohydroxamic acid, and high-resolution X-ray crystallographic structure of the enzyme-inhibitor complex Biochemistry. 34: 3742-3749. PMID 7893671 DOI: 10.1021/Bi00011A032 |
0.741 |
|
| 1994 |
Allen KN, Lavie A, Farber GK, Glasfeld A, Petsko GA, Ringe D. Isotopic exchange plus substrate and inhibition kinetics of D-xylose isomerase do not support a proton-transfer mechanism Biochemistry. 33: 1481-1487. PMID 8312268 DOI: 10.1021/Bi00172A026 |
0.697 |
|
| 1994 |
Lavie A, Allen KN, Petsko GA, Ringe D. X-ray crystallographic structures of D-xylose isomerase-substrate complexes position the substrate and provide evidence for metal movement during catalysis Biochemistry. 33: 5469-5480. PMID 8180169 DOI: 10.2210/Pdb1Xyb/Pdb |
0.714 |
|
| 1994 |
Allen KN, Lavie A, Glasfeld A, Tanada TN, Gerrity DP, Carlson SC, Farber GK, Petsko GA, Ringe D. Role of the divalent metal ion in sugar binding, ring opening, and isomerization by D-xylose isomerase: Replacement of a catalytic metal by an amino acid Biochemistry. 33: 1488-1494. PMID 7906142 DOI: 10.1021/Bi00172A027 |
0.725 |
|
| 1993 |
Petsko G, Ringe D, Allen K, Lavie A, Gerhart-Mueller E, Clifton J, Hasson M, Fujita S, Sugio S, Xhang X, Davenport R, Lolis E, Neidhart D, Kenyon G, Gerlt J, et al. The structural enzymology of proton-transfer reactions Protein Engineering, Design and Selection. 6: 37. DOI: 10.1093/Protein/6.Supplement.37-A |
0.764 |
|
| 1989 |
Allen KN, Abeles RH. Inhibition of pig liver esterase by trifluoromethyl ketones: modulators of the catalytic reaction alter inhibition kinetics. Biochemistry. 28: 135-40. PMID 2706239 DOI: 10.1021/Bi00427A020 |
0.663 |
|
| 1989 |
Allen KN, Abeles RH. Inhibition kinetics of acetylcholinesterase with fluoromethyl ketones. Biochemistry. 28: 8466-73. PMID 2605196 DOI: 10.1021/Bi00447A029 |
0.603 |
|
| Show low-probability matches. |