Ozgun Gokce, PhD - Publications

2004-2009 Brain Mind Institute, EPFL, Lausanne, Vaud, Switzerland 
 2009-2016 mcp Stanford University, Palo Alto, CA 
 2016- Institut für Schlaganfall- und Demenzforschung (ISD) Ludwig-Maximilians-Universität München, München, Bayern, Germany 

21 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Stanley G, Gokce O, Malenka RC, Südhof TC, Quake SR. Continuous and Discrete Neuron Types of the Adult Murine Striatum. Neuron. PMID 31813651 DOI: 10.1016/j.neuron.2019.11.004  1
2018 Zhang B, Gokce O, Hale WD, Brose N, Südhof TC. Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses. The Journal of Experimental Medicine. PMID 29724786 DOI: 10.1084/jem.20172162  1
2017 Chen LY, Jiang M, Zhang B, Gokce O, Südhof TC. Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins. Neuron. 94: 611-625.e4. PMID 28472659 DOI: 10.1016/j.neuron.2017.04.011  1
2016 Zhang B, Seigneur E, Wei P, Gokce O, Morgan J, Südhof TC. Developmental plasticity shapes synaptic phenotypes of autism-associated neuroligin-3 mutations in the calyx of Held. Molecular Psychiatry. PMID 27725662 DOI: 10.1038/mp.2016.157  1
2016 Gokce O, Stanley GM, Treutlein B, Neff NF, Camp JG, Malenka RC, Rothwell PE, Fuccillo MV, Südhof TC, Quake SR. Cellular Taxonomy of the Mouse Striatum as Revealed by Single-Cell RNA-Seq. Cell Reports. 16: 1126-37. PMID 27425622 DOI: 10.1016/j.celrep.2016.06.059  1
2015 Zhang B, Chen LY, Liu X, Maxeiner S, Lee SJ, Gokce O, Südhof TC. Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses. Neuron. 87: 781-96. PMID 26291161 DOI: 10.1016/j.neuron.2015.07.020  1
2015 Fuccillo MV, Földy C, Gökce Ö, Rothwell PE, Sun GL, Malenka RC, Südhof TC. Single-Cell mRNA Profiling Reveals Cell-Type-Specific Expression of Neurexin Isoforms. Neuron. 87: 326-40. PMID 26182417 DOI: 10.1016/j.neuron.2015.06.028  0.48
2014 Rothwell PE, Fuccillo MV, Maxeiner S, Hayton SJ, Gokce O, Lim BK, Fowler SC, Malenka RC, Südhof TC. Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors. Cell. 158: 198-212. PMID 24995986 DOI: 10.1016/j.cell.2014.04.045  1
2014 Treutlein B, Gokce O, Quake SR, Südhof TC. Cartography of neurexin alternative splicing mapped by single-molecule long-read mRNA sequencing. Proceedings of the National Academy of Sciences of the United States of America. 111: E1291-9. PMID 24639501 DOI: 10.1073/pnas.1403244111  1
2014 Smith MR, Syed A, Lukacsovich T, Purcell J, Barbaro BA, Worthge SA, Wei SR, Pollio G, Magnoni L, Scali C, Massai L, Franceschini D, Camarri M, Gianfriddo M, Diodato E, ... ... Gokce O, et al. A potent and selective Sirtuin 1 inhibitor alleviates pathology in multiple animal and cell models of Huntington's disease. Human Molecular Genetics. 23: 2995-3007. PMID 24436303 DOI: 10.1093/hmg/ddu010  1
2013 La Rosa S, Benicchi T, Bettinetti L, Ceccarelli I, Diodato E, Federico C, Fiengo P, Franceschini D, Gokce O, Heitz F, Lazzeroni G, Luthi-Carter R, Magnoni L, Miragliotta V, Scali C, et al. Fused 3-Hydroxy-3-trifluoromethylpyrazoles Inhibit Mutant Huntingtin Toxicity. Acs Medicinal Chemistry Letters. 4: 979-84. PMID 24900595 DOI: 10.1021/ml400251g  1
2013 Gokce O, Südhof TC. Membrane-tethered monomeric neurexin LNS-domain triggers synapse formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 14617-28. PMID 24005312 DOI: 10.1523/JNEUROSCI.1232-13.2013  1
2011 Seredenina T, Gokce O, Luthi-Carter R. Decreased striatal RGS2 expression is neuroprotective in Huntington's disease (HD) and exemplifies a compensatory aspect of HD-induced gene regulation. Plos One. 6: e22231. PMID 21779398 DOI: 10.1371/journal.pone.0022231  1
2010 Zucker B, Kama JA, Kuhn A, Thu D, Orlando LR, Dunah AW, Gokce O, Taylor DM, Lambeck J, Friedrich B, Lindenberg KS, Faull RL, Weiller C, Young AB, Luthi-Carter R. Decreased Lin7b expression in layer 5 pyramidal neurons may contribute to impaired corticostriatal connectivity in huntington disease. Journal of Neuropathology and Experimental Neurology. 69: 880-95. PMID 20720508 DOI: 10.1097/NEN.0b013e3181ed7a41  1
2010 Gambazzi L, Gokce O, Seredenina T, Katsyuba E, Runne H, Markram H, Giugliano M, Luthi-Carter R. Diminished activity-dependent brain-derived neurotrophic factor expression underlies cortical neuron microcircuit hypoconnectivity resulting from exposure to mutant huntingtin fragments. The Journal of Pharmacology and Experimental Therapeutics. 335: 13-22. PMID 20624994 DOI: 10.1124/jpet.110.167551  1
2010 Luthi-Carter R, Taylor DM, Pallos J, Lambert E, Amore A, Parker A, Moffitt H, Smith DL, Runne H, Gokce O, Kuhn A, Xiang Z, Maxwell MM, Reeves SA, Bates GP, et al. SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 7927-32. PMID 20378838 DOI: 10.1073/pnas.1002924107  1
2009 Rudinskiy N, Kaneko YA, Beesen AA, Gokce O, Régulier E, Déglon N, Luthi-Carter R. Diminished hippocalcin expression in Huntington's disease brain does not account for increased striatal neuron vulnerability as assessed in primary neurons. Journal of Neurochemistry. 111: 460-72. PMID 19686238 DOI: 10.1111/j.1471-4159.2009.06344.x  1
2009 Gokce O, Runne H, Kuhn A, Luthi-Carter R. Short-term striatal gene expression responses to brain-derived neurotrophic factor are dependent on MEK and ERK activation. Plos One. 4: e5292. PMID 19390590 DOI: 10.1371/journal.pone.0005292  1
2008 Runne H, Régulier E, Kuhn A, Zala D, Gokce O, Perrin V, Sick B, Aebischer P, Déglon N, Luthi-Carter R. Dysregulation of gene expression in primary neuron models of Huntington's disease shows that polyglutamine-related effects on the striatal transcriptome may not be dependent on brain circuitry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 9723-31. PMID 18815258 DOI: 10.1523/JNEUROSCI.3044-08.2008  1
2008 Jan A, Gokce O, Luthi-Carter R, Lashuel HA. The ratio of monomeric to aggregated forms of Abeta40 and Abeta42 is an important determinant of amyloid-beta aggregation, fibrillogenesis, and toxicity. The Journal of Biological Chemistry. 283: 28176-89. PMID 18694930 DOI: 10.1074/jbc.M803159200  1
2004 Guzeloglu-Kayisli O, Kayisli UA, Amankulor NM, Voorhees JR, Gokce O, DiLuna ML, Laurans MS, Luleci G, Gunel M. Krev1 interaction trapped-1/cerebral cavernous malformation-1 protein expression during early angiogenesis. Journal of Neurosurgery. 100: 481-7. PMID 15287459 DOI: 10.3171/ped.2004.100.5.0481  1
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