Christian Gachet - Publications

Strasbourg 1 

131 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Aguilar A, Weber J, Boscher J, Freund M, Ziessel C, Eckly A, Magnenat S, Bourdon C, Hechler B, Mangin PH, Gachet C, Lanza F, Léon C. Combined deficiency of RAB32 and RAB38 in the mouse mimics Hermansky-Pudlak syndrome and critically impairs thrombosis. Blood Advances. 3: 2368-2380. PMID 31399401 DOI: 10.1182/bloodadvances.2019031286  1
2019 Angénieux C, Dupuis A, Gachet C, de la Salle H, Maître B. Cell surface expression of HLA I molecules as a marker of young platelets. Journal of Thrombosis and Haemostasis : Jth. PMID 31207003 DOI: 10.1111/jth.14537  0.64
2019 El Mdawar MB, Maître B, Magnenat S, Gachet C, Hechler B, de la Salle H. The ATP-gated P2X ion channel contributes to the severity of antibody-mediated Transfusion-Related Acute Lung Injury in mice. Scientific Reports. 9: 5159. PMID 30914724 DOI: 10.1038/s41598-019-41742-9  1
2019 Strassel C, Magiera MM, Dupuis A, Batzenschlager M, Hovasse A, Pleines I, Guéguen P, Eckly A, Moog S, Mallo L, Kimmerlin Q, Chappaz S, Strub JM, Kathiresan N, de la Salle H, ... ... Gachet C, et al. An essential role for α4A-tubulin in platelet biogenesis. Life Science Alliance. 2. PMID 30760556 DOI: 10.26508/lsa.201900309  0.64
2019 Nechipurenko DY, Receveur N, Yakimenko AO, Shepelyuk TO, Yakusheva AA, Kerimov RR, Obydennyy SI, Eckly A, Léon C, Gachet C, Grishchuk EL, Ataullakhanov FI, Mangin PH, Panteleev MA. Clot Contraction Drives the Translocation of Procoagulant Platelets to Thrombus Surface. Arteriosclerosis, Thrombosis, and Vascular Biology. 39: 37-47. PMID 30580561 DOI: 10.1161/ATVBAHA.118.311390  0.68
2018 Selvadurai MV, Brazilek RJ, Moon MJ, Rinckel JY, Eckly A, Gachet C, Meikle PJ, Nandurkar HH, Nesbitt WS, Hamilton JR. The PI 3-kinase PI3KC2α regulates mouse platelet membrane structure and function independently of membrane lipid composition. Febs Letters. PMID 30421419 DOI: 10.1002/1873-3468.13295  0.36
2018 Eckly A, Rinckel JY, Proamer F, Gachet C. High-Resolution 3D Imaging of Megakaryocytes Using Focused Ion Beam-Scanning Electron Microscopy. Methods in Molecular Biology (Clifton, N.J.). 1812: 217-231. PMID 30171581 DOI: 10.1007/978-1-4939-8585-2_13  0.36
2018 Aguilar A, Boscher J, Pertuy F, Gachet C, Léon C. Three-Dimensional Culture in a Methylcellulose-Based Hydrogel to Study the Impact of Stiffness on Megakaryocyte Differentiation. Methods in Molecular Biology (Clifton, N.J.). 1812: 139-153. PMID 30171577 DOI: 10.1007/978-1-4939-8585-2_9  0.68
2018 Ravanat C, Dupuis A, Marpaux N, Naegelen C, Mourey G, Isola H, Laforêt M, Morel P, Gachet C. In vitro quality of amotosalen-UVA pathogen-inactivated mini-pool plasma prepared from whole blood stored overnight. Vox Sanguinis. PMID 30079963 DOI: 10.1111/vox.12697  0.72
2018 Beutier H, Hechler B, Godon O, Wang Y, Gillis CM, de Chaisemartin L, Gouel-Chéron A, Magnenat S, Macdonald LE, Murphy AJ, Chollet-Martin S, Longrois D, Gachet C, Bruhns P, et al. Platelets expressing IgG receptor FcγRIIA/CD32A determine the severity of experimental anaphylaxis. Science Immunology. 3. PMID 29654057 DOI: 10.1126/sciimmunol.aan5997  1
2018 Ouadi A, Bekaert V, Receveur N, Thomas L, Lanza F, Marchand P, Gachet C, Mangin PH, Brasse D, Laquerriere P. Imaging thrombosis withTc-labeled RAM.1-antibody in vivo. Nuclear Medicine and Biology. 61: 21-27. PMID 29625391 DOI: 10.1016/j.nucmedbio.2018.03.003  0.36
2018 Mangin PH, Onselaer MB, Receveur N, Le Lay N, Hardy AT, Wilson C, Sanchez X, Loyau S, Dupuis A, Babar AK, Miller JL, Philippou H, Hughes CE, Herr AB, Ariëns RA, ... ... Gachet C, et al. Immobilized fibrinogen activates human platelets through GPVI. Haematologica. PMID 29472360 DOI: 10.3324/haematol.2017.182972  0.36
2017 Leiva O, Leon C, Ng SK, Mangin P, Gachet C, Ravid K. The Role of Extracellular Matrix Stiffness in Megakaryocyte Development and Function. American Journal of Hematology. PMID 29247535 DOI: 10.1002/ajh.25008  0.36
2017 Hechler B, Ravanat C, Gachet C. Amotosalen/UVA pathogen inactivation technology reduces platelet activability, induces apoptosis and accelerates clearance. Haematologica. 102: e502-e503. PMID 29192131 DOI: 10.3324/haematol.2017.180539  1
2017 Lavergne M, Janus-Bell E, Schaff M, Gachet C, Mangin PH. Platelet Integrins in Tumor Metastasis: Do They Represent a Therapeutic Target? Cancers. 9. PMID 28956830 DOI: 10.3390/cancers9100133  0.36
2017 Ayme-Dietrich E, Lawson R, Côté F, de Tapia C, Da Silva S, Ebel C, Hechler B, Gachet C, Guyonnet J, Rouillard H, Stoltz J, Quentin E, Banas S, Daubeuf F, Frossard N, et al. Serotonergic 5-HT2B receptors in mitral valvulopathy: bone marrow mobilization of endothelial progenitors. British Journal of Pharmacology. PMID 28806488 DOI: 10.1111/bph.13981  1
2017 Alberio L, Ravanat C, Hechler B, Mangin PH, Lanza F, Gachet C. Delayed-onset of procoagulant signalling revealed by kinetic analysis of COAT platelet formation. Thrombosis and Haemostasis. PMID 28382366 DOI: 10.1160/TH16-09-0711  1
2017 Saultier P, Vidal L, Canault M, Bernot D, Falaise C, Pouymayou C, Bordet JC, Saut N, Rostan A, Baccini V, Peiretti F, Favier M, Lucca P, Deleuze JF, Olaso R, ... ... Gachet C, et al. Macrothrombocytopenia and dense granule deficiency associated with FLI1 variants: ultrastructural and pathogenic features. Haematologica. PMID 28255014 DOI: 10.3324/haematol.2016.153577  0.36
2017 Benbarche S, Strassel C, Angénieux C, Mallo L, Freund M, Gachet C, Lanza F, de la Salle H. Dual role of IL-21 in megakaryopoiesis and platelet homeostasis. Haematologica. PMID 28057742 DOI: 10.3324/haematol.2016.143958  0.64
2016 Ollivier V, Roques C, Receveur N, Gratz M, Feldman L, Letourneur D, Gachet C, Mangin PH, Jandrot-Perrus M. Bioreactivity of stent material: Activation of platelets, coagulation, leukocytes and endothelial cell dysfunction in vitro. Platelets. 1-11. PMID 28032527 DOI: 10.1080/09537104.2016.1252836  0.36
2016 Mammadova-Bach E, Zigrino P, Brucker C, Bourdon C, Freund M, De Arcangelis A, Abrams SI, Orend G, Gachet C, Mangin PH. Platelet integrin α6β1 controls lung metastasis through direct binding to cancer cell-derived ADAM9. Jci Insight. 1: e88245. PMID 27699237 DOI: 10.1172/jci.insight.88245  0.4
2016 Eckly A, Rinckel JY, Proamer F, Ulas N, Joshi S, Whiteheart SW, Gachet C. Respective contributions of single and compound granule fusion to secretion by activated platelets. Blood. 128: 2538-2549. PMID 27625359 DOI: 10.1182/blood-2016-03-705681  0.36
2016 Aguilar A, Pertuy F, Eckly A, Strassel C, Collin D, Gachet C, Lanza F, Léon C. Importance of environmental stiffness for megakaryocyte differentiation and proplatelet formation. Blood. PMID 27503502 DOI: 10.1182/blood-2016-02-699959  0.68
2016 Lecchi A, Femia EA, Paoletta S, Dupuis A, Ohlmann P, Gachet C, Jacobson KA, Machura K, Podda GM, Zieger B, Cattaneo M. Inherited dysfunctional platelet P2Y12 receptor mutations associated with bleeding disorders. Hamostaseologie. 36. PMID 27487748 DOI: 10.5482/HAMO-16-03-0010  0.52
2016 Léon C, Dupuis A, Gachet C, Lanza F. The contribution of mouse models to the understanding of constitutional thrombocytopenia. Haematologica. 101: 896-908. PMID 27478199 DOI: 10.3324/haematol.2015.139394  0.68
2016 Podoplelova NA, Sveshnikova AN, Kotova YN, Eckly A, Receveur N, Nechipurenko DY, Obydennyi SI, Kireev II, Gachet C, Ataullakhanov FI, Mangin PH, Panteleev MA. Coagulation factors bound to procoagulant platelets concentrate in cap structures to promote clotting. Blood. 128: 1745-55. PMID 27432876 DOI: 10.1182/blood-2016-02-696898  0.36
2016 Ohlmann P, Hechler B, Chafey P, Ravanat C, Isola H, Wiesel ML, Cazenave JP, Gachet C. Hemostatic properties and protein expression profile of therapeutic apheresis plasma treated with amotosalen and ultraviolet A for pathogen inactivation. Transfusion. 56: 2239-47. PMID 27250038 DOI: 10.1111/trf.13670  1
2016 Tang C, Wang Y, Lei D, Huang L, Wang G, Chi Q, Zheng Y, Gachet C, Mangin PH, Zhu L. Standardization of a well-controlled in vivo mouse model of thrombus formation induced by mechanical injury. Thrombosis Research. 141: 49-57. PMID 26967532 DOI: 10.1016/j.thromres.2016.02.032  0.4
2016 Strassel C, Brouard N, Mallo L, Receveur N, Mangin P, Eckly A, Bieche I, Tarte K, Gachet C, Lanza F. Aryl hydrocarbon receptor-dependent enrichment of a megakaryocytic precursor with a high potential to produce proplatelets. Blood. 127: 2231-40. PMID 26966088 DOI: 10.1182/blood-2015-09-670208  0.36
2016 Angénieux C, Maître B, Eckly A, Lanza F, Gachet C, de la Salle H. Time-Dependent Decay of mRNA and Ribosomal RNA during Platelet Aging and Its Correlation with Translation Activity. Plos One. 11: e0148064. PMID 26808079 DOI: 10.1371/journal.pone.0148064  0.64
2015 Schaff M, Gachet C, Mangin PH. [Anti-platelets without a bleeding risk: novel targets and strategies]. Biologie Aujourd'Hui. 209: 211-28. PMID 26820829 DOI: 10.1051/jbio/2015023  0.36
2015 Dupuis A, Heim V, Ohlmann P, Gachet C. In Vitro Binding of [³H]PSB-0413 to P2Y₁₂ Receptors Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. 71: 1.35.1-1.35.19. PMID 26646192 DOI: 10.1002/0471141755.ph0135s71  0.4
2015 Hechler B, Gachet C. Purinergic Receptors in Thrombosis and Inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 2307-15. PMID 26359511 DOI: 10.1161/ATVBAHA.115.303395  1
2015 Maurer E, Schaff M, Receveur N, Bourdon C, Mercier L, Nieswandt B, Dubois C, Jandrot-Perrus M, Goetz J, Lanza F, Gachet C, Mangin PH. Fibrillar cellular fibronectin supports efficient platelet function and procoagulant activity. Thrombosis and Haemostasis. 114. PMID 26245230 DOI: 10.1160/TH14-11-0958  0.4
2015 Mammadova-Bach E, Ollivier V, Loyau S, Schaff M, Dumont B, Favier R, Freyburger G, Latger-Cannard V, Nieswandt B, Gachet C, Mangin PH, Jandrot-Perrus M. Platelet glycoprotein VI binds to polymerized fibrin and promotes thrombin generation. Blood. PMID 25977585 DOI: 10.1182/blood-2015-02-629717  0.4
2015 Ciciliano JC, Sakurai Y, Myers DR, Fay ME, Hechler B, Meeks S, Li R, Dixon JB, Lyon LA, Gachet C, Lam WA. Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach. Blood. PMID 25931587 DOI: 10.1182/blood-2015-02-628594  0.4
2015 Donnet T, Ravanat C, Eckly A, Maurer E, Alame G, Ziessel C, Mangin PH, Freund M, Cazenave JP, Gachet C, Rendu F. Dehydration of blood platelets by zeodration: in vitro characterization and hemostatic properties in vivo. Transfusion. 55: 2207-18. PMID 25856501 DOI: 10.1111/trf.13121  0.4
2015 Mountford JK, Petitjean C, Putra HW, McCafferty JA, Setiabakti NM, Lee H, Tønnesen LL, McFadyen JD, Schoenwaelder SM, Eckly A, Gachet C, Ellis S, Voss AK, Dickins RA, Hamilton JR, et al. The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function. Nature Communications. 6: 6535. PMID 25779105 DOI: 10.1038/ncomms7535  0.4
2015 Gampe K, Haverkamp S, Robson SC, Gachet C, Hüser L, Acker-Palmer A, Zimmermann H. NTPDase2 and the P2Y1 receptor are not required for mammalian eye formation. Purinergic Signalling. 11: 155-60. PMID 25504514 DOI: 10.1007/s11302-014-9440-5  0.4
2015 Maître B, Magnenat S, Heim V, Ravanat C, Evans RJ, de la Salle H, Gachet C, Hechler B. The P2X1 receptor is required for neutrophil extravasation during lipopolysaccharide-induced lethal endotoxemia in mice. Journal of Immunology (Baltimore, Md. : 1950). 194: 739-49. PMID 25480563 DOI: 10.4049/jimmunol.1401786  0.4
2015 Lecchi A, Razzari C, Paoletta S, Dupuis A, Nakamura L, Ohlmann P, Gachet C, Jacobson KA, Zieger B, Cattaneo M. Identification of a new dysfunctional platelet P2Y12 receptor variant associated with bleeding diathesis. Blood. 125: 1006-13. PMID 25428217 DOI: 10.1182/blood-2013-07-517896  0.4
2015 Alame G, Mangin PH, Freund M, Riehl N, Magnenat S, Petitou M, Hechler B, Gachet C. EP217609, a neutralisable dual-action FIIa/FXa anticoagulant, with antithrombotic effects in arterial thrombosis. Thrombosis and Haemostasis. 113: 385-95. PMID 25374268 DOI: 10.1160/TH14-05-0399  0.4
2015 Strassel C, Kubovcakova L, Mangin PH, Ravanat C, Freund M, Skoda RC, Denis CV, Dupuis A, Herbrecht R, Gachet C, Lanza F. Haemorrhagic and thrombotic diatheses in mouse models with thrombocytosis. Thrombosis and Haemostasis. 113: 414-25. PMID 25298269 DOI: 10.1160/TH14-08-0667  0.72
2014 Shinozaki Y, Nomura M, Iwatsuki K, Moriyama Y, Gachet C, Koizumi S. Microglia trigger astrocyte-mediated neuroprotection via purinergic gliotransmission. Scientific Reports. 4: 4329. PMID 24710318 DOI: 10.1038/srep04329  0.4
2014 Prudent M, D'Alessandro A, Cazenave JP, Devine DV, Gachet C, Greinacher A, Lion N, Schubert P, Steil L, Thiele T, Tissot JD, Völker U, Zolla L. Proteome changes in platelets after pathogen inactivation--an interlaboratory consensus. Transfusion Medicine Reviews. 28: 72-83. PMID 24685438 DOI: 10.1016/j.tmrv.2014.02.002  0.4
2014 Tersteeg C, Heijnen HF, Eckly A, Pasterkamp G, Urbanus RT, Maas C, Hoefer IE, Nieuwland R, Farndale RW, Gachet C, de Groot PG, Roest M. FLow-induced PRotrusions (FLIPRs): a platelet-derived platform for the retrieval of microparticles by monocytes and neutrophils. Circulation Research. 114: 780-91. PMID 24406984 DOI: 10.1161/CIRCRESAHA.114.302361  0.36
2014 Shin JW, Buxboim A, Spinler KR, Swift J, Christian DA, Hunter CA, Léon C, Gachet C, Dingal PC, Ivanovska IL, Rehfeldt F, Chasis JA, Discher DE. Contractile forces sustain and polarize hematopoiesis from stem and progenitor cells. Cell Stem Cell. 14: 81-93. PMID 24268694 DOI: 10.1016/j.stem.2013.10.009  0.4
2014 Pertuy F, Eckly A, Weber J, Proamer F, Rinckel JY, Lanza F, Gachet C, Léon C. Myosin IIA is critical for organelle distribution and F-actin organization in megakaryocytes and platelets. Blood. 123: 1261-9. PMID 24243973 DOI: 10.1182/blood-2013-06-508168  0.4
2014 Eckly A, Heijnen H, Pertuy F, Geerts W, Proamer F, Rinckel JY, Léon C, Lanza F, Gachet C. Biogenesis of the demarcation membrane system (DMS) in megakaryocytes Blood. 123: 921-930. PMID 24152908 DOI: 10.1182/blood-2013-03-492330  0.4
2013 Chin Y, Kishi M, Sekino M, Nakajo F, Abe Y, Terazono Y, Hiroyuki O, Kato F, Koizumi S, Gachet C, Hisatsune T. Involvement of glial P2Y₁ receptors in cognitive deficit after focal cerebral stroke in a rodent model. Journal of Neuroinflammation. 10: 95. PMID 23890321 DOI: 10.1186/1742-2094-10-95  0.4
2013 Pleines I, Dütting S, Cherpokova D, Eckly A, Meyer I, Morowski M, Krohne G, Schulze H, Gachet C, Debili N, Brakebusch C, Nieswandt B. Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac1 and Cdc42. Blood. 122: 3178-87. PMID 23861250 DOI: 10.1182/blood-2013-03-487942  0.36
2013 Schaff M, Tang C, Maurer E, Bourdon C, Receveur N, Eckly A, Hechler B, Arnold C, De Arcangelis A, Nieswandt B, Denis CV, Lefebvre O, Georges-Labouesse E, Gachet C, Lanza F, et al. Integrin α6β1 is the main receptor for vascular laminins and plays a role in platelet adhesion, activation, and arterial thrombosis Circulation. 128: 541-552. PMID 23797810 DOI: 10.1161/CIRCULATIONAHA.112.000799  0.4
2013 Delabranche X, Boisramé-Helms J, Asfar P, Berger A, Mootien Y, Lavigne T, Grunebaum L, Lanza F, Gachet C, Freyssinet JM, Toti F, Meziani F. Microparticles are new biomarkers of septic shock-induced disseminated intravascular coagulopathy. Intensive Care Medicine. 39: 1695-703. PMID 23793890 DOI: 10.1007/s00134-013-2993-x  0.4
2013 Maurer E, Tang C, Schaff M, Bourdon C, Receveur N, Ravanat C, Eckly A, Hechler B, Gachet C, Lanza F, Mangin PH. Targeting platelet GPIbβ reduces platelet adhesion, GPIb signaling and thrombin generation and prevents arterial thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 33: 1221-9. PMID 23559635 DOI: 10.1161/ATVBAHA.112.301013  0.4
2013 Noguchi Y, Shinozaki Y, Fujishita K, Shibata K, Imura Y, Morizawa Y, Gachet C, Koizumi S. Astrocytes protect neurons against methylmercury via ATP/P2Y(1) receptor-mediated pathways in astrocytes. Plos One. 8: e57898. PMID 23469098 DOI: 10.1371/journal.pone.0057898  0.4
2013 Hechler B, Ohlmann P, Chafey P, Ravanat C, Eckly A, Maurer E, Mangin P, Isola H, Cazenave JP, Gachet C. Preserved functional and biochemical characteristics of platelet components prepared with amotosalen and ultraviolet A for pathogen inactivation. Transfusion. 53: 1187-200. PMID 23067365 DOI: 10.1111/j.1537-2995.2012.03923.x  1
2013 Ohlmann P, Lecchi A, El-Tayeb A, Müller CE, Cattaneo M, Gachet C. The platelet P2Y12 receptor under normal and pathological conditions. Assessment with the radiolabeled selective antagonist [3H]PSB-0413 Purinergic Signalling. 9: 59-66. PMID 22892887 DOI: 10.1007/s11302-012-9329-0  0.4
2012 Angénieux C, Waharte F, Gidon A, Signorino-Gelo F, Wurtz V, Hojeij R, Proamer F, Gachet C, Van Dorsselaer A, Hanau D, Salamero J, de la Salle H. Lysosomal-associated transmembrane protein 5 (LAPTM5) is a molecular partner of CD1e. Plos One. 7: e42634. PMID 22880058 DOI: 10.1371/journal.pone.0042634  0.64
2012 Suyama S, Sunabori T, Kanki H, Sawamoto K, Gachet C, Koizumi S, Okano H. Purinergic signaling promotes proliferation of adult mouse subventricular zone cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9238-47. PMID 22764232 DOI: 10.1523/JNEUROSCI.4001-11.2012  0.4
2012 Morel O, El Ghannudi S, Hess S, Reydel A, Crimizade U, Jesel L, Radulescu B, Wiesel ML, Gachet C, Ohlmann P. The extent of P2Y12 inhibition by clopidogrel in diabetes mellitus patients with acute coronary syndrome is not related to glycaemic control: roles of white blood cell count and body weight. Thrombosis and Haemostasis. 108: 338-48. PMID 22740070 DOI: 10.1160/TH11-12-0876  0.36
2012 Horckmans M, Robaye B, Léon-Gόmez E, Lantz N, Unger P, Dol-Gleizes F, Clouet S, Cammarata D, Schaeffer P, Savi P, Gachet C, Balligand JL, Dessy C, Boeynaems JM, Communi D. P2Y(4) nucleotide receptor: a novel actor in post-natal cardiac development. Angiogenesis. 15: 349-60. PMID 22437266 DOI: 10.1007/s10456-012-9265-1  0.56
2012 Muller C, Caillard S, Jesel L, El Ghannudi S, Ohlmann P, Sauleau E, Hannedouche T, Gachet C, Moulin B, Morel O. Association of estimated GFR with platelet inhibition in patients treated with clopidogrel. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 59: 777-85. PMID 22425260 DOI: 10.1053/j.ajkd.2011.12.027  0.36
2012 Mangin PH, Tang C, Bourdon C, Loyau S, Freund M, Hechler B, Gachet C, Jandrot-Perrus M. A humanized glycoprotein VI (GPVI) mouse model to assess the antithrombotic efficacies of anti-GPVI agents. The Journal of Pharmacology and Experimental Therapeutics. 341: 156-63. PMID 22238212 DOI: 10.1124/jpet.111.189050  1
2012 Léon C, Evert K, Dombrowski F, Pertuy F, Eckly A, Laeuffer P, Gachet C, Greinacher A. Romiplostim administration shows reduced megakaryocyte response-capacity and increased myelofibrosis in a mouse model of MYH9-RD. Blood. 119: 3333-41. PMID 22234693 DOI: 10.1182/blood-2011-08-373811  0.68
2012 Eckly A, Strassel C, Cazenave JP, Lanza F, Léon C, Gachet C. Characterization of megakaryocyte development in the native bone marrow environment. Methods in Molecular Biology (Clifton, N.J.). 788: 175-92. PMID 22130708 DOI: 10.1007/978-1-61779-307-3_13  0.4
2012 Gayol S, Kirchgesner T, Kopferschmitt J, Meyer N, Sauleau E, Wiesel ML, Cazenave JP, Gachet C, Lanza F. Evaluation of soluble glycoprotein V as a marker of venous thromboembolism. Thrombosis and Haemostasis. 107: 184-7. PMID 22116210 DOI: 10.1160/TH11-09-0630  0.4
2012 Strassel C, Eckly A, Léon C, Moog S, Cazenave JP, Gachet C, Lanza F. Hirudin and heparin enable efficient megakaryocyte differentiation of mouse bone marrow progenitors. Experimental Cell Research. 318: 25-32. PMID 22008103 DOI: 10.1016/j.yexcr.2011.10.003  0.4
2011 Hechler B, Gachet C. P2 receptors and platelet function. Purinergic Signalling. 7: 293-303. PMID 21792575 DOI: 10.1007/s11302-011-9247-6  1
2011 Zerr M, Hechler B, Freund M, Magnenat S, Lanois I, Cazenave JP, Léon C, Gachet C. Major contribution of the P2Y₁receptor in purinergic regulation of TNFα-induced vascular inflammation. Circulation. 123: 2404-13. PMID 21576651 DOI: 10.1161/CIRCULATIONAHA.110.002139  1
2011 Hechler B, Freund M, Alame G, Leguay C, Gaertner S, Cazenave JP, Petitou M, Gachet C. The antithrombotic activity of EP224283, a neutralizable dual factor Xa inhibitor/glycoprotein IIbIIIa antagonist, exceeds that of the coadministered parent compounds. The Journal of Pharmacology and Experimental Therapeutics. 338: 412-20. PMID 21527535 DOI: 10.1124/jpet.111.181321  1
2011 Hechler B, Gachet C. Comparison of two murine models of thrombosis induced by atherosclerotic plaque injury. Thrombosis and Haemostasis. 105: S3-12. PMID 21479341 DOI: 10.1160/THS10-11-0730  1
2011 Johnstone DB, Zhang J, George B, Léon C, Gachet C, Wong H, Parekh R, Holzman LB. Podocyte-specific deletion of Myh9 encoding nonmuscle myosin heavy chain 2A predisposes mice to glomerulopathy. Molecular and Cellular Biology. 31: 2162-70. PMID 21402784 DOI: 10.1128/MCB.05234-11  0.4
2011 Morel O, El Ghannudi S, Jesel L, Radulescu B, Meyer N, Wiesel ML, Caillard S, Campia U, Moulin B, Gachet C, Ohlmann P. Cardiovascular mortality in chronic kidney disease patients undergoing percutaneous coronary intervention is mainly related to impaired P2Y12 inhibition by clopidogrel. Journal of the American College of Cardiology. 57: 399-408. PMID 21251579 DOI: 10.1016/j.jacc.2010.09.032  0.36
2011 Schaff M, Receveur N, Bourdon C, Wurtz V, Denis CV, Orend G, Gachet C, Lanza F, Mangin PH. Novel function of tenascin-C, a matrix protein relevant to atherosclerosis, in platelet recruitment and activation under flow. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 117-24. PMID 20651280 DOI: 10.1161/ATVBAHA.110.206375  0.36
2010 Bonello L, Tantry US, Marcucci R, Blindt R, Angiolillo DJ, Becker R, Bhatt DL, Cattaneo M, Collet JP, Cuisset T, Gachet C, Montalescot G, Jennings LK, Kereiakes D, Sibbing D, et al. Consensus and future directions on the definition of high on-treatment platelet reactivity to adenosine diphosphate. Journal of the American College of Cardiology. 56: 919-33. PMID 20828644 DOI: 10.1016/j.jacc.2010.04.047  0.4
2010 El Ghannudi S, Ohlmann P, Meyer N, Wiesel ML, Radulescu B, Chauvin M, Bareiss P, Gachet C, Morel O. Impact of P2Y12 inhibition by clopidogrel on cardiovascular mortality in unselected patients treated by percutaneous coronary angioplasty: a prospective registry. Jacc. Cardiovascular Interventions. 3: 648-56. PMID 20630458 DOI: 10.1016/j.jcin.2010.03.003  0.36
2010 Ohlmann P, de Castro S, Brown GG, Gachet C, Jacobson KA, Harden TK. Quantification of recombinant and platelet P2Y(1) receptors utilizing a [(125)I]-labeled high-affinity antagonist 2-iodo-N(6)-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate ([(125)I]MRS2500). Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 62: 344-51. PMID 20594939 DOI: 10.1016/j.phrs.2010.05.007  0.4
2010 de Castro S, Maruoka H, Hong K, Kilbey SM, Costanzi S, Hechler B, Brown GG, Gachet C, Harden TK, Jacobson KA. Functionalized congeners of P2Y1 receptor antagonists: 2-alkynyl (N)-methanocarba 2'-deoxyadenosine 3',5'-bisphosphate analogues and conjugation to a polyamidoamine (PAMAM) dendrimer carrier. Bioconjugate Chemistry. 21: 1190-205. PMID 20565071 DOI: 10.1021/bc900569u  0.4
2010 Bender M, Eckly A, Hartwig JH, Elvers M, Pleines I, Gupta S, Krohne G, Jeanclos E, Gohla A, Gurniak C, Gachet C, Witke W, Nieswandt B. ADF/n-cofilin-dependent actin turnover determines platelet formation and sizing. Blood. 116: 1767-75. PMID 20530287 DOI: 10.1182/blood-2010-03-274340  0.36
2010 Ravanat C, Strassel C, Hechler B, Schuhler S, Chicanne G, Payrastre B, Gachet C, Lanza F. A central role of GPIb-IX in the procoagulant function of platelets that is independent of the 45-kDa GPIbalpha N-terminal extracellular domain. Blood. 116: 1157-64. PMID 20457869 DOI: 10.1182/blood-2010-01-266080  1
2010 Reininger AJ, Bernlochner I, Penz SM, Ravanat C, Smethurst P, Farndale RW, Gachet C, Brandl R, Siess W. A 2-step mechanism of arterial thrombus formation induced by human atherosclerotic plaques. Journal of the American College of Cardiology. 55: 1147-58. PMID 20223370 DOI: 10.1016/j.jacc.2009.11.051  0.72
2010 Laplante MA, Monassier L, Freund M, Bousquet P, Gachet C. The purinergic P2Y1 receptor supports leptin secretion in adipose tissue Endocrinology. 151: 2060-2070. PMID 20185765 DOI: 10.1210/en.2009-1134  0.4
2010 Pleines I, Eckly A, Elvers M, Hagedorn I, Eliautou S, Bender M, Wu X, Lanza F, Gachet C, Brakebusch C, Nieswandt B. Multiple alterations of platelet functions dominated by increased secretion in mice lacking Cdc42 in platelets. Blood. 115: 3364-73. PMID 20139097 DOI: 10.1182/blood-2009-09-242271  0.36
2009 Eliautou S, Mangin PH, Walter U, Gachet C, Lanza F. Normal filopodia extension in VASP-deficient platelets upon activation by adhesive matrices or soluble agonists. Thrombosis and Haemostasis. 102: 792-4. PMID 19806269 DOI: 10.1160/TH09-06-0379  0.36
2009 Kim Y, Hechler B, Gao ZG, Gachet C, Jacobson KA. PEGylated dendritic unimolecular micelles as versatile carriers for ligands of G protein-coupled receptors. Bioconjugate Chemistry. 20: 1888-98. PMID 19785401 DOI: 10.1021/bc9001689  0.4
2009 Reiner S, Ziegler N, Leon C, Lorenz K, von Hayn K, Gachet C, Lohse MJ, Hoffmann C. beta-Arrestin-2 interaction and internalization of the human P2Y1 receptor are dependent on C-terminal phosphorylation sites. Molecular Pharmacology. 76: 1162-71. PMID 19741005 DOI: 10.1124/mol.109.060467  0.4
2009 Strassel C, Eckly A, Léon C, Petitjean C, Freund M, Cazenave JP, Gachet C, Lanza F. Intrinsic impaired proplatelet formation and microtubule coil assembly of megakaryocytes in a mouse model of Bernard-Soulier syndrome. Haematologica. 94: 800-10. PMID 19377075 DOI: 10.3324/haematol.2008.001032  0.68
2009 Maître B, Angénieux C, Wurtz V, Layre E, Gilleron M, Collmann A, Mariotti S, Mori L, Fricker D, Cazenave JP, van Dorsselaer A, Gachet C, de Libero G, Puzo G, Hanau D, et al. The assembly of CD1e is controlled by an N-terminal propeptide which is processed in endosomal compartments. The Biochemical Journal. 419: 661-8. PMID 19196239 DOI: 10.1042/BJ20082204  0.4
2009 Ravanat C, Wurtz V, Ohlmann P, Fichter M, Cazenave JP, Vandorsselaer A, Lanza F, Gachet C. Use of tandem Biacore-mass spectrometry to identify platelet membrane targets of novel monoclonal antibodies. Analytical Biochemistry. 386: 237-43. PMID 19135971 DOI: 10.1016/j.ab.2008.12.010  0.72
2009 Smyth SS, Woulfe DS, Weitz JI, Gachet C, Conley PB, Goodman SG, Roe MT, Kuliopulos A, Moliterno DJ, French PA, Steinhubl SR, Becker RC. G-protein-coupled receptors as signaling targets for antiplatelet therapy. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 449-57. PMID 19023091 DOI: 10.1161/ATVBAHA.108.176388  0.4
2009 Eckly A, Strassel C, Freund M, Cazenave JP, Lanza F, Gachet C, Léon C. Abnormal megakaryocyte morphology and proplatelet formation in mice with megakaryocyte-restricted MYH9 inactivation. Blood. 113: 3182-9. PMID 18984861 DOI: 10.1182/blood-2008-06-164061  0.68
2009 Kim Y, Klutz AM, Hechler B, Gao ZG, Gachet C, Jacobson KA. Application of the functionalized congener approach to dendrimer-based signaling agents acting through A(2A) adenosine receptors. Purinergic Signalling. 5: 39-50. PMID 18600474 DOI: 10.1007/s11302-008-9113-3  0.4
2008 Aleil B, Jacquemin L, De Poli F, Zaehringer M, Collet JP, Montalescot G, Cazenave JP, Dickele MC, Monassier JP, Gachet C. Clopidogrel 150 mg/day to overcome low responsiveness in patients undergoing elective percutaneous coronary intervention: results from the VASP-02 (Vasodilator-Stimulated Phosphoprotein-02) randomized study. Jacc. Cardiovascular Interventions. 1: 631-8. PMID 19463377 DOI: 10.1016/j.jcin.2008.09.004  0.56
2008 Aleil B, Kessler L, Meyer N, Wiesel ML, Simeoni J, Cazenave JP, Pinget M, Gachet C, Lanza F. Plasma levels of soluble platelet glycoprotein V are linked to fasting blood glucose in patients with type 2 diabetes. Thrombosis and Haemostasis. 100: 713-5. PMID 18841299  0.56
2008 Hechler B, Freund M, Ravanat C, Magnenat S, Cazenave JP, Gachet C. Reduced atherosclerotic lesions in P2Y1/apolipoprotein E double-knockout mice: the contribution of non-hematopoietic-derived P2Y1 receptors. Circulation. 118: 754-63. PMID 18663083 DOI: 10.1161/CIRCULATIONAHA.108.788927  1
2008 Atterbury-Thomas AE, Leon C, Gachet C, Forsythe ID, Evans RJ. Contribution of P2Y(1) receptors to ADP signalling in mouse spinal cord cultures. Neuroscience Letters. 435: 190-3. PMID 18343032 DOI: 10.1016/j.neulet.2008.02.034  0.4
2008 Gao ZG, Hechler B, Besada P, Gachet C, Jacobson KA. Caged agonist of P2Y1 and P2Y12 receptors for light-directed facilitation of platelet aggregation. Biochemical Pharmacology. 75: 1341-7. PMID 18199424 DOI: 10.1016/j.bcp.2007.10.037  1
2008 Kim Y, Hechler B, Klutz AM, Gachet C, Jacobson KA. Toward multivalent signaling across G protein-coupled receptors from poly(amidoamine) dendrimers. Bioconjugate Chemistry. 19: 406-11. PMID 18176997 DOI: 10.1021/bc700327u  1
2007 Lantz N, Hechler B, Ravanat C, Cazenave JP, Gachet C. A high concentration of ADP induces weak platelet granule secretion independently of aggregation and thromboxane A2 production. Thrombosis and Haemostasis. 98: 1145-7. PMID 18000625  1
2007 Schoenwaelder SM, Ono A, Sturgeon S, Chan SM, Mangin P, Maxwell MJ, Turnbull S, Mulchandani M, Anderson K, Kauffenstein G, Rewcastle GW, Kendall J, Gachet C, Salem HH, Jackson SP. Identification of a unique co-operative phosphoinositide 3-kinase signaling mechanism regulating integrin alpha IIb beta 3 adhesive function in platelets. The Journal of Biological Chemistry. 282: 28648-58. PMID 17673465 DOI: 10.1074/jbc.M704358200  0.4
2007 Léon C, Eckly A, Hechler B, Aleil B, Freund M, Ravanat C, Jourdain M, Nonne C, Weber J, Tiedt R, Gratacap MP, Severin S, Cazenave JP, Lanza F, Skoda R, ... Gachet C, et al. Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion. Blood. 110: 3183-91. PMID 17664350 DOI: 10.1182/blood-2007-03-080184  1
2007 Wurtz V, Hechler B, Ohlmann P, Isola H, Schaeffer-Reiss C, Cazenave JP, Van Dorsselaer A, Gachet C. Identification of platelet factor 4 and beta-thromboglobulin by profiling and liquid chromatography tandem mass spectrometry of supernatant peptides in stored apheresis and buffy-coat platelet concentrates. Transfusion. 47: 1099-101. PMID 17524104 DOI: 10.1111/j.1537-2995.2007.01260.x  1
2007 Hohenstein B, Renk S, Lang K, Daniel C, Freund M, Léon C, Amann KU, Gachet C, Hugo CP. P2Y1 gene deficiency protects from renal disease progression and capillary rarefaction during passive crescentic glomerulonephritis. Journal of the American Society of Nephrology : Jasn. 18: 494-505. PMID 17215444 DOI: 10.1681/ASN.2006050439  0.4
2006 Gachet C, Hechler B, Nonne C, Cazenave JP, Lanza F, Aleil B. [Atherothrombosis: transposition of the models to the clinic and reciprocally]. Therapie. 61: 389-94. PMID 17243267  1
2006 Aleil B, Meyer N, Wolff V, Kientz D, Wiesel ML, Gachet C, Cazenave JP, Lanza F. Plasma glycoprotein V levels in the general population: normal distribution, associated parameters and implications for clinical studies. Thrombosis and Haemostasis. 96: 505-11. PMID 17003930  0.56
2006 Abbracchio MP, Burnstock G, Boeynaems JM, Barnard EA, Boyer JL, Kennedy C, Knight GE, Fumagalli M, Gachet C, Jacobson KA, Weisman GA. International Union of Pharmacology LVIII: update on the P2Y G protein-coupled nucleotide receptors: from molecular mechanisms and pathophysiology to therapy. Pharmacological Reviews. 58: 281-341. PMID 16968944 DOI: 10.1124/pr.58.3.3  0.4
2006 Gachet C, Léon C, Hechler B. The platelet P2 receptors in arterial thrombosis. Blood Cells, Molecules & Diseases. 36: 223-7. PMID 16466948 DOI: 10.1016/j.bcmd.2005.12.024  1
2006 Tanneur V, Duranton C, Brand VB, Sandu CD, Akkaya C, Kasinathan RS, Gachet C, Sluyter R, Barden JA, Wiley JS, Lang F, Huber SM. Purinoceptors are involved in the induction of an osmolyte permeability in malaria-infected and oxidized human erythrocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 133-5. PMID 16267125 DOI: 10.1096/fj.04-3371fje  0.4
2006 Hechler B, Nonne C, Roh EJ, Cattaneo M, Cazenave JP, Lanza F, Jacobson KA, Gachet C. MRS2500 [2-iodo-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate], a potent, selective, and stable antagonist of the platelet P2Y1 receptor with strong antithrombotic activity in mice. The Journal of Pharmacology and Experimental Therapeutics. 316: 556-63. PMID 16236815 DOI: 10.1124/jpet.105.094037  1
2005 Léon C, Freund M, Latchoumanin O, Farret A, Petit P, Cazenave JP, Gachet C. The P2Y(1) receptor is involved in the maintenance of glucose homeostasis and in insulin secretion in mice. Purinergic Signalling. 1: 145-51. PMID 18404499 DOI: 10.1007/s11302-005-6209-x  0.68
2005 Aleil B, Meyer N, Cazenave JP, Mossard JM, Gachet C. High stability of blood samples for flow cytometric analysis of VASP phosphorylation to measure the clopidogrel responsiveness in patients with coronary artery disease. Thrombosis and Haemostasis. 94: 886-7. PMID 16270649 DOI: 10.1160/TH05-04-0886  0.56
2005 Tolhurst G, Vial C, Léon C, Gachet C, Evans RJ, Mahaut-Smith MP. Interplay between P2Y(1), P2Y(12), and P2X(1) receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling. Blood. 106: 1644-51. PMID 15914557 DOI: 10.1182/blood-2005-02-0725  0.68
2005 Gachet C, Hechler B. The platelet P2 receptors in thrombosis. Seminars in Thrombosis and Hemostasis. 31: 162-7. PMID 15852219 DOI: 10.1055/s-2005-869521  1
2005 Hechler B, Cattaneo M, Gachet C. The P2 receptors in platelet function. Seminars in Thrombosis and Hemostasis. 31: 150-61. PMID 15852218 DOI: 10.1055/s-2005-869520  1
2005 Hechler B, Magnenat S, Zighetti ML, Kassack MU, Ullmann H, Cazenave JP, Evans R, Cattaneo M, Gachet C. Inhibition of platelet functions and thrombosis through selective or nonselective inhibition of the platelet P2 receptors with increasing doses of NF449 [4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis-benzene-1,3-disulfonic acid octasodium salt]. The Journal of Pharmacology and Experimental Therapeutics. 314: 232-43. PMID 15792995 DOI: 10.1124/jpet.105.084673  1
2005 Nonne C, Lenain N, Hechler B, Mangin P, Cazenave JP, Gachet C, Lanza F. Importance of platelet phospholipase Cgamma2 signaling in arterial thrombosis as a function of lesion severity. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1293-8. PMID 15774906 DOI: 10.1161/01.ATV.0000163184.02484.69  1
2005 Abbracchio MP, Burnstock G, Boeynaems JM, Barnard EA, Boyer JL, Kennedy C, Miras-Portugal MT, King BF, Gachet C, Jacobson KA, Weisman GA. The recently deorphanized GPR80 (GPR99) proposed to be the P2Y15 receptor is not a genuine P2Y receptor. Trends in Pharmacological Sciences. 26: 8-9. PMID 15629198 DOI: 10.1016/  0.4
2005 Baurand A, Eckly A, Hechler B, Kauffenstein G, Galzi JL, Cazenave JP, Léon C, Gachet C. Differential regulation and relocalization of the platelet P2Y receptors after activation: a way to avoid loss of hemostatic properties? Molecular Pharmacology. 67: 721-33. PMID 15602005 DOI: 10.1124/mol.104.004846  0.4
2005 Martinez-Pinna J, Gurung IS, Vial C, Leon C, Gachet C, Evans RJ, Mahaut-Smith MP. Direct voltage control of signaling via P2Y1 and other Galphaq-coupled receptors. The Journal of Biological Chemistry. 280: 1490-8. PMID 15528188 DOI: 10.1074/jbc.M407783200  0.32
2004 Calvert JA, Atterbury-Thomas AE, Leon C, Forsythe ID, Gachet C, Evans RJ. Evidence for P2Y1, P2Y2, P2Y6 and atypical UTP-sensitive receptors coupled to rises in intracellular calcium in mouse cultured superior cervical ganglion neurons and glia. British Journal of Pharmacology. 143: 525-32. PMID 15466449 DOI: 10.1038/sj.bjp.0705959  0.4
2004 Ohlmann P, Hechler B, Cazenave JP, Gachet C. Measurement and manipulation of [Ca2+]i in suspensions of platelets and cell cultures. Methods in Molecular Biology (Clifton, N.J.). 273: 229-50. PMID 15308805 DOI: 10.1385/1-59259-783-1:229  1
2004 Cazenave JP, Ohlmann P, Cassel D, Eckly A, Hechler B, Gachet C. Preparation of washed platelet suspensions from human and rodent blood. Methods in Molecular Biology (Clifton, N.J.). 272: 13-28. PMID 15226531 DOI: 10.1385/1-59259-782-3:013  1
2004 Mangin P, David T, Lavaud V, Cranmer SL, Pikovski I, Jackson SP, Berndt MC, Cazenave JP, Gachet C, Lanza F. Identification of a novel 14-3-3zeta binding site within the cytoplasmic tail of platelet glycoprotein Ibalpha. Blood. 104: 420-7. PMID 15054037 DOI: 10.1182/blood-2003-08-2881  0.56
2004 Haserück N, Erl W, Pandey D, Tigyi G, Ohlmann P, Ravanat C, Gachet C, Siess W. The plaque lipid lysophosphatidic acid stimulates platelet activation and platelet-monocyte aggregate formation in whole blood: involvement of P2Y1 and P2Y12 receptors. Blood. 103: 2585-92. PMID 14645014 DOI: 10.1182/blood-2003-04-1127  0.72
2004 Leon C, Alex M, Klocke A, Morgenstern E, Moosbauer C, Eckly A, Spannagl M, Gachet C, Engelmann B. Platelet ADP receptors contribute to the initiation of intravascular coagulation. Blood. 103: 594-600. PMID 12969982 DOI: 10.1182/blood-2003-05-1385  0.36
2003 Cazenave JP, Gachet C, Lanza F, Wiesel ML. Platelets and arterial thrombosis Bulletin De L'Academie Nationale De Medecine. 187: 35-46. PMID 14556452  0.4
2003 Leon C, Ravanat C, Freund M, Cazenave JP, Gachet C. Differential involvement of the P2Y1 and P2Y12 receptors in platelet procoagulant activity. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 1941-7. PMID 12933533 DOI: 10.1161/01.ATV.0000092127.16125.E6  0.72
2003 Hechler B, Lenain N, Marchese P, Vial C, Heim V, Freund M, Cazenave JP, Cattaneo M, Ruggeri ZM, Evans R, Gachet C. A role of the fast ATP-gated P2X1 cation channel in thrombosis of small arteries in vivo. The Journal of Experimental Medicine. 198: 661-7. PMID 12913094 DOI: 10.1084/jem.20030144  1
2003 Mangin P, Yuan Y, Goncalves I, Eckly A, Freund M, Cazenave JP, Gachet C, Jackson SP, Lanza F. Signaling role for phospholipase C gamma 2 in platelet glycoprotein Ib alpha calcium flux and cytoskeletal reorganization. Involvement of a pathway distinct from FcR gamma chain and Fc gamma RIIA. The Journal of Biological Chemistry. 278: 32880-91. PMID 12813055 DOI: 10.1074/jbc.M302333200  0.56
2003 Abbracchio MP, Boeynaems JM, Barnard EA, Boyer JL, Kennedy C, Miras-Portugal MT, King BF, Gachet C, Jacobson KA, Weisman GA, Burnstock G. Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family. Trends in Pharmacological Sciences. 24: 52-5. PMID 12559763 DOI: 10.1016/S0165-6147(02)00038-X  0.4
2002 Raboisson P, Baurand A, Cazenave JP, Gachet C, Schultz D, Spiess B, Bourguignon JJ. A general approach toward the synthesis of C-nucleoside pyrazolo[1,5-a]-1,3,5-triazines and their 3',5'-bisphosphate C-nucleotide analogues as the first reported in vivo stable P2Y(1)-receptor antagonists. The Journal of Organic Chemistry. 67: 8063-71. PMID 12423133  0.56
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