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Allen M. Spiegel, M.D. - Publications

Affiliations: 
NIH - NIDDK 
Area:
endocrinology, diabetis
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Year Citation  Score
2013 Spiegel AM. G proteins--the disease spectrum expands. The New England Journal of Medicine. 368: 2515-6. PMID 23802519 DOI: 10.1056/Nejme1304751  0.323
2006 Scacheri PC, Davis S, Odom DT, Crawford GE, Perkins S, Halawi MJ, Agarwal SK, Marx SJ, Spiegel AM, Meltzer PS, Collins FS. Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis. Plos Genetics. 2: e51. PMID 16604156 DOI: 10.1371/Journal.Pgen.0020051  0.301
2005 Rosen JE, Costouros NG, Lorang D, Burns AL, Alexander HR, Skarulis MC, Cochran C, Pingpank JF, Marx SJ, Spiegel AM, Libutti SK. Gland size is associated with changes in gene expression profiles in sporadic parathyroid adenomas. Annals of Surgical Oncology. 12: 412-6. PMID 15915376 DOI: 10.1245/Aso.2005.03.103  0.3
2004 Spiegel AM, Weinstein LS. Inherited diseases involving g proteins and g protein-coupled receptors. Annual Review of Medicine. 55: 27-39. PMID 14746508 DOI: 10.1146/Annurev.Med.55.091902.103843  0.328
2001 Crabtree JS, Scacheri PC, Ward JM, Garrett-Beal L, Emmert-Buck MR, Edgemon KA, Lorang D, Libutti SK, Chandrasekharappa SC, Marx SJ, Spiegel AM, Collins FS. A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors. Proceedings of the National Academy of Sciences of the United States of America. 98: 1118-23. PMID 11158604 DOI: 10.1073/Pnas.98.3.1118  0.303
2000 Goebel SU, Peghini PL, Goldsmith PK, Spiegel AM, Gibril F, Raffeld M, Jensen RT, Serrano J. Expression of the calcium-sensing receptor in gastrinomas. The Journal of Clinical Endocrinology and Metabolism. 85: 4131-7. PMID 11095444 DOI: 10.1210/Jcem.85.11.6963  0.319
2000 Spiegel AM. G protein defects in signal transduction. Hormone Research. 53: 17-22. PMID 10971097 DOI: 10.1159/000023526  0.346
2000 Bianco P, Riminucci M, Majolagbe A, Kuznetsov SA, Collins MT, Mankani MH, Corsi A, Bone HG, Wientroub S, Spiegel AM, Fisher LW, Robey PG. Mutations of the GNAS1 gene, stromal cell dysfunction, and osteomalacic changes in non-McCune-Albright fibrous dysplasia of bone. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 15: 120-8. PMID 10646121 DOI: 10.1359/Jbmr.2000.15.1.120  0.3
2000 Goebel SU, Heppner C, Burns AL, Marx SJ, Spiegel AM, Zhuang Z, Lubensky IA, Gibril F, Jensen RT, Serrano J. Genotype/phenotype correlation of multiple endocrine neoplasia type 1 gene mutations in sporadic gastrinomas. The Journal of Clinical Endocrinology and Metabolism. 85: 116-23. PMID 10634374 DOI: 10.1210/Jcem.85.1.6260  0.3
1999 Libutti SK, Alexander HR, Bartlett DL, Sampson ML, Ruddel ME, Skarulis M, Marx SJ, Spiegel AM, Simmonds W, Remaley AT. Kinetic analysis of the rapid intraoperative parathyroid hormone assay in patients during operation for hyperparathyroidism. Surgery. 126: 1145-50; discussion . PMID 10598200 DOI: 10.1067/Msy.2099.101835  0.309
1999 Marx SJ, Agarwal SK, Heppner C, Kim YS, Kester MB, Goldsmith PK, Skarulis MC, Spiegel AM, Burns AL, Debelenko LV, Zhuang Z, Lubensky IA, Liotta LA, Emmert-Buck MR, Guru SC, et al. The gene for multiple endocrine neoplasia type 1: recent findings. Bone. 25: 119-22. PMID 10423035 DOI: 10.1016/S8756-3282(99)00112-X  0.311
1999 Riminucci M, Liu B, Corsi A, Shenker A, Spiegel AM, Robey PG, Bianco P. The histopathology of fibrous dysplasia of bone in patients with activating mutations of the Gs alpha gene: site-specific patterns and recurrent histological hallmarks. The Journal of Pathology. 187: 249-58. PMID 10365102 DOI: 10.1002/(Sici)1096-9896(199901)187:2<249::Aid-Path222>3.0.Co;2-J  0.311
1999 Goldsmith PK, Fan GF, Ray K, Shiloach J, McPhie P, Rogers KV, Spiegel AM. Expression, purification, and biochemical characterization of the amino-terminal extracellular domain of the human calcium receptor. The Journal of Biological Chemistry. 274: 11303-9. PMID 10196220 DOI: 10.1074/Jbc.274.16.11303  0.312
1999 Berger AC, Libutti SK, Bartlett DL, Skarulis MG, Marx SJ, Spiegel AM, Doppman JL, Alexander HR. Heterogeneous gland size in sporadic multiple gland parathyroid hyperplasia. Journal of the American College of Surgeons. 188: 382-9. PMID 10195722 DOI: 10.1016/S1072-7515(98)00317-2  0.363
1998 Doppman JL, Skarulis MC, Chang R, Alexander HR, Bartlett D, Libutti SK, Marx SJ, Spiegel AM. Hypocalcemic stimulation and nonselective venous sampling for localizing parathyroid adenomas: work in progress. Radiology. 208: 145-51. PMID 9646806 DOI: 10.1148/Radiology.208.1.9646806  0.339
1997 Libutti SK, Bartlett DL, jaskowiak NT, Skarulis M, Marx SJ, Spiegel AM, Fraker DL, Doppman JL, Shawker TJ, Alexander HR. The role of thyroid resection during reoperation for persistent or recurrent hyperparathyroidism. Surgery. 122: 1183-7; discussion 1. PMID 9426436 DOI: 10.1016/S0039-6060(97)90225-7  0.344
1997 Chandrasekharappa SC, Guru SC, Manickam P, Olufemi SE, Collins FS, Emmert-Buck MR, Debelenko LV, Zhuang Z, Lubensky IA, Liotta LA, Crabtree JS, Wang Y, Roe BA, Weisemann J, Boguski MS, ... ... Spiegel AM, et al. Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science (New York, N.Y.). 276: 404-7. PMID 9103196 DOI: 10.1126/Science.276.5311.404  0.313
1997 Spiegel AM. The molecular basis of disorders caused by defects in G proteins. Hormone Research. 47: 89-96. PMID 9050946 DOI: 10.1159/000185441  0.339
1996 Doppman JL, Skarulis MC, Chen CC, Chang R, Pass HI, Fraker DL, Alexander HR, Niederle B, Marx SJ, Norton JA, Wells SA, Spiegel AM. Parathyroid adenomas in the aortopulmonary window. Radiology. 201: 456-62. PMID 8888240 DOI: 10.1148/Radiology.201.2.8888240  0.312
1996 Jaskowiak N, Norton JA, Alexander HR, Doppman JL, Shawker T, Skarulis M, Marx S, Spiegel AM, Fraker DL. A prospective trial evaluating a standard approach to reoperation for missed parathyroid adenoma. Annals of Surgery. 224: 308-322. PMID 8813259 DOI: 10.1097/00000658-199609000-00007  0.333
1996 Dong Q, Brucker-Davis F, Weintraub BD, Smallridge RC, Carr FE, Battey J, Spiegel AM, Shenker A. Screening of candidate oncogenes in human thyrotroph tumors: absence of activating mutations of the G alpha q, G alpha 11, G alpha s, or thyrotropin-releasing hormone receptor genes. The Journal of Clinical Endocrinology and Metabolism. 81: 1134-40. PMID 8772588 DOI: 10.1210/Jcem.81.3.8772588  0.314
1996 Spiegel AM. Mutations in G proteins and G protein-coupled receptors in endocrine disease. The Journal of Clinical Endocrinology and Metabolism. 81: 2434-42. PMID 8675557 DOI: 10.1210/Jcem.81.7.8675557  0.304
1994 Shenker A, Weinstein LS, Sweet DE, Spiegel AM. An activating Gs alpha mutation is present in fibrous dysplasia of bone in the McCune-Albright syndrome. The Journal of Clinical Endocrinology and Metabolism. 79: 750-5. PMID 8077356 DOI: 10.1210/Jcem.79.3.8077356  0.318
1993 Dohlman HG, Goldsmith P, Spiegel AM, Thorner J. Pheromone action regulates G-protein alpha-subunit myristoylation in the yeast Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 90: 9688-92. PMID 8415763 DOI: 10.1073/Pnas.90.20.9688  0.308
1993 Shenker A, Weinstein LS, Moran A, Pescovitz OH, Charest NJ, Boney CM, Van Wyk JJ, Merino MJ, Feuillan PP, Spiegel AM. Severe endocrine and nonendocrine manifestations of the McCune-Albright syndrome associated with activating mutations of stimulatory G protein GS. The Journal of Pediatrics. 123: 509-18. PMID 8410501 DOI: 10.1016/S0022-3476(05)80943-6  0.329
1993 Sugg SL, Fraker DL, Alexander R, Doppman JL, Miller DL, Chang R, Skarulis MC, Marx SJ, Spiegel AM, Norton JA. Prospective evaluation of selective venous sampling for parathyroid hormone concentration in patients undergoing reoperations for primary hyperparathyroidism. Surgery. 114: 1004-9; discussion 1. PMID 8256203 DOI: 10.5555/Uri:Pii:0039606093903155  0.329
1992 Doherty GM, Doppman JL, Miller DL, Gee MS, Marx SJ, Spiegel AM, Aurbach GD, Pass HI, Brennan MF, Norton JA. Results of a multidisciplinary strategy for management of mediastinal parathyroid adenoma as a cause of persistent primary hyperparathyroidism. Annals of Surgery. 215: 101-6. PMID 1546895 DOI: 10.1097/00000658-199202000-00002  0.553
1992 Weinstein LS, Gejman PV, de Mazancourt P, American N, Spiegel AM. A heterozygous 4-bp deletion mutation in the Gs alpha gene (GNAS1) in a patient with Albright hereditary osteodystrophy. Genomics. 13: 1319-21. PMID 1505964 DOI: 10.1016/0888-7543(92)90056-X  0.309
1992 Friedman E, De Marco L, Gejman PV, Norton JA, Bale AE, Aurbach GD, Spiegel AM, Marx SJ. Allelic loss from chromosome 11 in parathyroid tumors. Cancer Research. 52: 6804-9. PMID 1360870  0.472
1991 Fraker DL, Travis WD, Merendino JJ, Zimering MB, Streeten EA, Weinstein LS, Marx SJ, Spiegel AM, Aurbach GD, Doppman JL. Locally recurrent parathyroid neoplasms as a cause for recurrent and persistent primary hyperparathyroidism. Annals of Surgery. 213: 58-65. PMID 1985539 DOI: 10.1097/00000658-199101000-00010  0.575
1991 Weinstein LS, Shenker A, Gejman PV, Merino MJ, Friedman E, Spiegel AM. Activating mutations of the stimulatory G protein in the McCune-Albright syndrome. The New England Journal of Medicine. 325: 1688-95. PMID 1944469 DOI: 10.1056/Nejm199112123252403  0.338
1991 Fargin A, Yamamoto K, Cotecchia S, Goldsmith PK, Spiegel AM, Lapetina EG, Caron MG, Lefkowitz RJ. Dual coupling of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein. Cellular Signalling. 3: 547-57. PMID 1786205 DOI: 10.1016/0898-6568(91)90031-O  0.31
1991 Marx SJ, Menczel J, Campbell G, Aurbach GD, Spiegel AM, Norton JA. Heterogeneous size of the parathyroid glands in familial multiple endocrine neoplasia type 1. Clinical Endocrinology. 35: 521-6. PMID 1685109 DOI: 10.1111/J.1365-2265.1991.Tb00938.X  0.526
1990 Fraker DL, Doppman JL, Shawker TH, Marx SJ, Spiegel AM, Norton JA. Undescended parathyroid adenoma: an important etiology for failed operations for primary hyperparathyroidism. World Journal of Surgery. 14: 342-8. PMID 2368436 DOI: 10.1007/Bf01658522  0.346
1990 Friedman E, Bale AE, Marx SJ, Norton JA, Arnold A, Tu T, Aurbach GD, Spiegel AM. Genetic abnormalities in sporadic parathyroid adenomas. The Journal of Clinical Endocrinology and Metabolism. 71: 293-7. PMID 2199477 DOI: 10.1210/Jcem-71-2-293  0.509
1989 Spiegel AM. Receptor-effector coupling by G-proteins implications for endocrinology. Trends in Endocrinology and Metabolism: Tem. 1: 72-6. PMID 18411094 DOI: 10.1016/1043-2760(89)90006-4  0.31
1989 Friedman E, Sakaguchi K, Bale AE, Falchetti A, Streeten E, Zimering MB, Weinstein LS, McBride WO, Nakamura Y, Brandi ML, Norton JA, Aurbach GD, Spiegel AM, Marx SJ. Clonality of parathyroid tumors in familial multiple endocrine neoplasia type 1 New England Journal of Medicine. 321: 213-218. PMID 2568586 DOI: 10.1056/Nejm198907273210402  0.534
1988 Milligan G, Mullaney I, Unson CG, Marshall L, Spiegel AM, McArdle H. GTP analogues promote release of the alpha subunit of the guanine nucleotide binding protein, Gi2, from membranes of rat glioma C6 BU1 cells. The Biochemical Journal. 254: 391-6. PMID 3140801 DOI: 10.1042/Bj2540391  0.305
1988 Collu R, Bouvier C, Lagacé G, Unson CG, Milligan G, Goldsmith P, Spiegel AM. Selective deficiency of guanine nucleotide-binding protein Go in two dopamine-resistant pituitary tumors. Endocrinology. 122: 1176-8. PMID 3125040 DOI: 10.1210/Endo-122-3-1176  0.307
1988 Spiegel AM. Guanine nucleotide binding proteins and signal transduction. Vitamins and Hormones. 44: 47-101. PMID 2853488 DOI: 10.1016/S0083-6729(08)60693-7  0.303
1988 Darling GE, Marx SJ, Spiegel AM, Aurbach GD, Norton JA. Prospective analysis of intraoperative and postoperative urinary cyclic adenosine 3',5'-monophosphate levels to predict outcome of patients undergoing reoperations for primary hyperparathyroidism. Surgery. 104: 1128-36. PMID 2848325  0.499
1988 Spiegel AM. Chapter 24. G-proteins as Receptor-Effector Couplers Annual Reports in Medicinal Chemistry. 23: 235-242. DOI: 10.1016/S0065-7743(08)60852-0  0.313
1987 Miller DL, Doppman JL, Chang R, Simmons JT, O'Leary TJ, Norton JA, Spiegel AM, Marx SJ, Aurbach GD. Angiographic ablation of parathyroid adenomas: lessons from a 10-year experience. Radiology. 165: 601-7. PMID 3685340 DOI: 10.1148/Radiology.165.3.3685340  0.552
1987 Miller DL, Doppman JL, Krudy AG, Shawker TH, Norton JA, Vucich JJ, Morrish KA, Marx SJ, Spiegel AM, Aurbach GD. Localization of parathyroid adenomas in patients who have undergone surgery. Part II. Invasive procedures. Radiology. 162: 138-41. PMID 3538146 DOI: 10.1148/Radiology.162.1.3538146  0.544
1987 Miller DL, Doppman JL, Shawker TH, Krudy AG, Norton JA, Vucich JJ, Morrish KA, Marx SJ, Spiegel AM, Aurbach GD. Localization of parathyroid adenomas in patients who have undergone surgery. Part I. Noninvasive imaging methods. Radiology. 162: 133-7. PMID 3538145 DOI: 10.1148/Radiology.162.1.3538145  0.531
1987 Kern KA, Shawker TH, Doppman JL, Miller DL, Marx SJ, Spiegel AM, Aurbach GD, Norton JA. The use of high-resolution ultrasound to locate parathyroid tumors during reoperations for primary hyperparathyroidism. World Journal of Surgery. 11: 579-85. PMID 3314177 DOI: 10.1007/Bf01655831  0.559
1987 Gawler D, Milligan G, Spiegel AM, Unson CG, Houslay MD. Abolition of the expression of inhibitory guanine nucleotide regulatory protein Gi activity in diabetes. Nature. 327: 229-32. PMID 3106832 DOI: 10.1038/327229A0  0.309
1986 Norton JA, Shawker TH, Jones BL, Spiegel AM, Marx SJ, Fitzpatrick L, Aurbach GD, Doppman JL. Intraoperative ultrasound and reoperative parathyroid surgery: an initial evaluation. World Journal of Surgery. 10: 631-9. PMID 3529650 DOI: 10.1007/Bf01655542  0.557
1986 Weinstock RS, Wright HN, Spiegel AM, Levine MA, Moses AM. Olfactory dysfunction in humans with deficient guanine nucleotide-binding protein. Nature. 322: 635-6. PMID 3018580 DOI: 10.1038/322635A0  0.341
1986 Levine MA, Jap TS, Mauseth RS, Downs RW, Spiegel AM. Activity of the stimulatory guanine nucleotide-binding protein is reduced in erythrocytes from patients with pseudohypoparathyroidism and pseudopseudohypoparathyroidism: biochemical, endocrine, and genetic analysis of Albright's hereditary osteodystrophy in six kindreds. The Journal of Clinical Endocrinology and Metabolism. 62: 497-502. PMID 3003142 DOI: 10.1210/Jcem-62-3-497  0.337
1986 Brandi ML, Aurbach GD, Fitzpatrick LA, Quarto R, Spiegel AM, Bliziotes MM, Norton JA, Doppman JL, Marx SJ. Parathyroid mitogenic activity in plasma from patients with familial multiple endocrine neoplasia type 1. The New England Journal of Medicine. 314: 1287-93. PMID 2871488 DOI: 10.1056/Nejm198605153142004  0.542
1985 Skibber JM, Reynolds JC, Spiegel AM, Marx SJ, Fitzpatrick LA, Aurbach GD, Wesley RA, Norton JA. Computerized technetium/thallium scans and parathyroid reoperation. Surgery. 98: 1077-82. PMID 3906975  0.505
1985 Doppman JL, Shawker TH, Krudy AG, Miller DL, Marx SJ, Spiegel AM, Norton JA, Brennan MF, Schaaf M, Aurbach GD. Parathymic parathyroid: CT, US, and angiographic findings. Radiology. 157: 419-23. PMID 3901107 DOI: 10.1148/Radiology.157.2.3901107  0.535
1985 Downs RW, Sekura RD, Levine MA, Spiegel AM. The inhibitory adenylate cyclase coupling protein in pseudohypoparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 61: 351-4. PMID 2989320 DOI: 10.1210/Jcem-61-2-351  0.336
1984 Krudy AG, Doppman JL, Marx SJ, Norton JA, Spiegel AM, Santora AC, Aurbach GD. Parathyroid aspiration directed by angiography: an alternative to venous sampling. Radiology. 152: 207-8. PMID 6729114 DOI: 10.1148/Radiology.152.1.6729114  0.522
1984 Krudy AG, Shawker TH, Doppman JL, Horvath K, Schneider PD, Norton JA, Marx SJ, Spiegel AM. Ultrasonic parathyroid localisation in previously operated patients. Clinical Radiology. 35: 113-8. PMID 6697653 DOI: 10.1016/S0009-9260(84)80007-0  0.325
1984 Krudy AG, Doppman JL, Miller DL, Norton JA, Marx SJ, Spiegel AM, Santora AC, Aurbach GD, Schaaf M. Detection of mediastinal parathyroid glands by nonselective digital arteriography. Ajr. American Journal of Roentgenology. 142: 693-5. PMID 6608224 DOI: 10.2214/Ajr.142.4.693  0.52
1984 Heinsimer JA, Davies AO, Downs RW, Levine MA, Spiegel AM, Drezner MK, De Lean A, Wreggett KA, Caron MG, Lefkowitz RJ. Impaired formation of beta-adrenergic receptor-nucleotide regulatory protein complexes in pseudohypoparathyroidism. The Journal of Clinical Investigation. 73: 1335-43. PMID 6325502 DOI: 10.1172/Jci111336  0.306
1983 Doppman JL, Krudy AG, Marx SJ, Saxe A, Schneider P, Norton JA, Spiegel AM, Downs RW, Schaaf M, Brennan ME, Schneider AB, Aurbach GD. Aspiration of enlarged parathyroid glands for parathyroid hormone assay. Radiology. 148: 31-5. PMID 6856859 DOI: 10.1148/Radiology.148.1.6856859  0.559
1983 Levine MA, Eil C, Downs RW, Spiegel AM. Deficient guanine nucleotide regulatory unit activity in cultured fibroblast membranes from patients with pseudohypoparathyroidism type I. a cause of impaired synthesis of 3',5'-cyclic AMP by intact and broken cells. The Journal of Clinical Investigation. 72: 316-24. PMID 6308048 DOI: 10.1172/Jci110971  0.301
1983 Levine MA, Downs RW, Moses AM, Breslau NA, Marx SJ, Lasker RD, Rizzoli RE, Aurbach GD, Spiegel AM. Resistance to multiple hormones in patients with pseudohypoparathyroidism. Association with deficient activity of guanine nucleotide regulatory protein. The American Journal of Medicine. 74: 545-56. PMID 6301273 DOI: 10.1016/0002-9343(83)91008-2  0.577
1983 Krudy AG, Doppman JL, Miller DL, Marx SJ, Norton JA, Santora AC, Lasker RD, Downs RW, Spiegel AM, Aurbach GD. Work in progress: abnormal parathyroid glands. Comparison of nonselective arterial digital arteriography, selective parathyroid arteriography, and venous digital arteriography as methods of detection. Radiology. 148: 23-9. PMID 6134300 DOI: 10.1148/Radiology.148.1.6134300  0.551
1982 Krudy AG, Doppman JL, Marx SJ, Brennan MF, Spiegel A, Aurback GD. Radiographic findings in recurrent parathyroid carcinoma Radiology. 142: 625-629. PMID 7063676 DOI: 10.1148/Radiology.142.3.7063676  0.32
1982 Brennan MF, Doppman JL, Kurdy AG, Marx SJ, Spiegel AM, Aurbach GD. Assessment of techniques for preoperative parathyroid gland localization in patients undergoing reoperation for hyperparathyroidism. Surgery. 91: 6-11. PMID 7054909  0.508
1982 Marx SJ, Spiegel AM, Levine MA, Rizzoli RE, Lasker RD, Santora AC, Downs RW, Aurbach GD. Familial hypocalciuric hypercalcemia: the relation to primary parathyroid hyperplasia. The New England Journal of Medicine. 307: 416-26. PMID 7045673 DOI: 10.1056/Nejm198208123070707  0.502
1982 Spiegel AM, Levine MA, Marx SJ, Aurbach GD. Pseudohypoparathyroidism: the molecular basis for hormone resistance--a retrospective. The New England Journal of Medicine. 307: 679-81. PMID 6287258 DOI: 10.1056/Nejm198209093071111  0.507
1982 Spiegel AM, Levine MA, Aurbach GD, Downs RW, Marx SJ, Lasker RD, Moses AM, Breslau NA. Deficiency of hormone receptor-adenylate cyclase coupling protein: basis for hormone resistance in pseudohypoparathyroidism. The American Journal of Physiology. 243: E37-42. PMID 6283911 DOI: 10.1152/Ajpendo.1982.243.1.E37  0.558
1982 Krawietz W, Downs RW, Spiegel AM, Aurbach GD. Vanadate stimulates adenylate cyclase via the guanine nucleotide regulatory protein by a mechanism differing from that of fluoride. Biochemical Pharmacology. 31: 843-8. PMID 6282277 DOI: 10.1016/0006-2952(82)90472-5  0.533
1982 Stock JL, Weintraub BD, Rosen SW, Aurbach GD, Spiegel AM, Marx SJ. Human chorionic gonadotropin subunit measurement in primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 54: 57-63. PMID 6274898 DOI: 10.1210/Jcem-54-1-57  0.583
1981 Brennan MF, Marx SJ, Doppman J, Costa J, Saxe A, Spiegel A, Krudy A, Aurbach G. Results of reoperation for persistent and recurrent hyperparathyroidism Annals of Surgery. 194: 671-676. PMID 7305478 DOI: 10.1097/00000658-198112000-00001  0.56
1981 Spiegel AM, Downs RW, Levine MA, Singer MJ, Krawietz W, Marx SJ, Woodard CJ, Reen SA, Aurbach GD. The role of guanine nucleotides in regulation of adenylate cyclase activity. Recent Progress in Hormone Research. 37: 635-65. PMID 7280358 DOI: 10.1016/B978-0-12-571137-1.50018-9  0.529
1981 Krudy AG, Doppman JL, Brennan MF, Marx SJ, Spiegel AM, Stock JL, Aurbach GD. The detection of mediastinal parathyroid glands by computed tomography, selective arteriography, and venous sampling: an analysis of 17 cases. Radiology. 140: 739-44. PMID 7280244 DOI: 10.1148/Radiology.140.3.7280244  0.528
1981 Stock JL, Krudy AG, Doppman JL, Jones AE, Brennan MF, Attie MF, Downs RW, Levine MA, Marx SJ, Spiegel AM, Aurbach GD. Parathyroid imaging after intraarterial injections of [75Se]selenomethionine. The Journal of Clinical Endocrinology and Metabolism. 52: 835-9. PMID 7228990 DOI: 10.1210/Jcem-52-5-835  0.548
1981 Spiegel AM, Marx SJ, Brennan MF, Brown EM, Downs RW, Gardner DG, Attie MF, Aurbach GD. Parathyroid function after parathyroidectomy: evaluation by measurement of urinary cAMP. Clinical Endocrinology. 15: 65-73. PMID 6273023 DOI: 10.1111/J.1365-2265.1981.Tb02749.X  0.499
1981 Downs RW, Reen SA, Levine MA, Aurbach GD, Spiegel AM. Cholera-toxin-dependent ADP-ribosylation of the adenylate cyclase regulatory protein in turkey erythrocyte membranes. Archives of Biochemistry and Biophysics. 209: 284-90. PMID 6269497 DOI: 10.1016/0003-9861(81)90282-4  0.516
1981 Krudy AG, Doppman JL, Marx SJ, Spiegel AM, Aurbach G, Brennan MF. Failure of ablation of a mediastinal parathyroid adenoma by repeated contrast staining. Radiology. 140: 63-5. PMID 6166026 DOI: 10.1148/Radiology.140.1.6166026  0.562
1981 Spiegel AM, Downs RW. Guanine nucleotides: key regulators of hormone receptor-adenylate cyclase interaction. Endocrine Reviews. 2: 275-305. PMID 6115747 DOI: 10.1210/Edrv-2-3-275  0.308
1980 Attie MF, Brown EM, Gardner DG, Spiegel AM, Aurbach GD. Characterization of the dopamine-responsive adenylate cyclase of bovine parathyroid cells and its relationship to parathyroid hormone secretion. Endocrinology. 107: 1776-81. PMID 7428692 DOI: 10.1210/Endo-107-6-1776  0.52
1980 Marx SJ, Aurbach GD, Spiegel AM. Incidence of primary hyperparathyroidism. The New England Journal of Medicine. 302: 1313. PMID 7366701  0.435
1980 Marx SJ, Spiegel AM, Brown EM, Downs RW, Attie MF, Stock JL, Levine MA, Aurbach GD. Urinary cyclic 3',5'-adenosine monophosphate (cAMP): an index of the action of parathyroid hormone on the kidney. Progress in Biochemical Pharmacology. 17: 182-9. PMID 6259655  0.477
1980 Spiegel AM, Eastman ST, Attie MF, Downs RW, Levine MA, Marx SJ, Stock JL, Saxe AW, Brennan MF, Aurbach GD. Intraoperative measurements of urinary cyclic AMP to guide surgery for primary hyperparathyroidism. The New England Journal of Medicine. 303: 1457-60. PMID 6253789 DOI: 10.1056/Nejm198012183032505  0.517
1980 Levine MA, Downs RW, Singer M, Marx SJ, Aurbach GD, Spiegel AM. Deficient activity of guanine nucleotide regulatory protein in erythrocytes from patients with pseudohypoparathyroidism. Biochemical and Biophysical Research Communications. 94: 1319-24. PMID 6249307 DOI: 10.1016/0006-291X(80)90563-X  0.562
1980 Marx SJ, Spiegel AM, Sharp ME, Brown EM, Gardner DG, Downs RW, Attie MF, Stock JL. Adenosine 3',5'-monophosphate response to parathyroid hormone: familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 50: 546-8. PMID 6244324 DOI: 10.1210/Jcem-50-3-546  0.316
1980 Downs RW, Spiegel AM, Singer M, Reen S, Aurbach GD. Fluoride stimulation of adenylate cyclase is dependent on the guanine nucleotide regulatory protein. The Journal of Biological Chemistry. 255: 949-54. PMID 6243302  0.473
1979 Brown EM, Gardner DG, Brennan MF, Marx SJ, Spiegel AM, Attie MF, Downs RW, Doppman JL, Aurbach CD. Calcium-regulated parathyroid hormone release in primary hyperparathyroidism: studies in vitro with dispersed parathyroid cells. The American Journal of Medicine. 66: 923-31. PMID 453225 DOI: 10.1016/0002-9343(79)90446-7  0.358
1979 Doppman JL, Marx S, Spiegel A, Brown E, Downs R, Brennan MF, Aurbach G. Differential diagnosis of brown tumor vs. cystic osteitis by arteriography and computed tomography Radiology. 131: 339-340. PMID 441315 DOI: 10.1148/131.2.339  0.527
1979 Spiegel AM, Downs RW, Aurbach GD. Separation of a guanine nucleotide regulatory unit from the adenylate cyclase complex with GTP affinity chromatography. Journal of Cyclic Nucleotide Research. 5: 3-17. PMID 438399  0.476
1979 Brown EM, Broadus AE, Brennan MF, Gardner DG, Marx SJ, Spiegel AM, Downs RW, Attie M, Aurbach GD. Direct comparison in vivo and in vitro of suppressibility of parathyroid function by calcium in primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 48: 604-10. PMID 429506 DOI: 10.1210/Jcem-48-4-604  0.556
1979 Brennan MF, Brown EM, Spiegel AM, Marx SJ, Doppman JL, Jones DC, Aurbach GD. Autotransplantation of cryopreserved parathyroid tissue in man. Annals of Surgery. 189: 139-42. PMID 426546 DOI: 10.1097/00000658-197902000-00002  0.559
1979 Doppman JL, Brown EM, Brennan MF, Spiegel A, Marx SJ, Aurbach GD. Angiographic ablation of parathyroid adenomas. Radiology. 130: 577-82. PMID 424518 DOI: 10.1148/130.3.577  0.539
1979 Brown EM, Brennan MF, Broadus AE, Marx SJ, Gardner DG, Spiegel AM, Downs RW, Attie MF, Aurbach GD. Human parathyroid autografts: comparison of function in vivo and in vitro. The Journal of Clinical Endocrinology and Metabolism. 48: 648-54. PMID 219003 DOI: 10.1210/Jcem-48-4-648  0.554
1978 Brown EM, Brennan MF, Hurwitz S, Windeck R, Marx SJ, Spiegel AM, Koehler JO, Gardner DG, Aurbach GD. Dispersed cells prepared from human parathyroid glands: distinct calcium sensitivity of adenomas vs. primary hyperplasia. The Journal of Clinical Endocrinology and Metabolism. 46: 267-75. PMID 750604 DOI: 10.1210/Jcem-46-2-267  0.55
1978 Brennan MF, Brown EM, Marx SJ, Spiegel AM, Broadus AE, Doppman JL, Webber B, Aurbach GD. Recurrent hyperparathyroidism from an autotransplanted parathyroid adenoma. The New England Journal of Medicine. 299: 1057-9. PMID 703772 DOI: 10.1056/Nejm197811092991909  0.543
1978 Marx SJ, Spiegel AM, Brown EM, Koehler JO, Gardner DG, Brennan MF, Aurbach GD. Divalent cation metabolism. Familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. The American Journal of Medicine. 65: 235-42. PMID 686009 DOI: 10.1016/0002-9343(78)90814-8  0.499
1978 Brennan MF, Doppman JL, Marx SJ, Spiegel AM, Brown EM, Aurbach GD. Reoperative parathyroid surgery for persistent hyperparathyroidism. Surgery. 83: 669-76. PMID 644460  0.509
1978 Marx SJ, Spiegel AM, Brown EM, Windeck R, Gardner DG, Downs RW, Attie M, Aurbach GD. Circulating parathyroid hormone activity: familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 47: 1190-7. PMID 233692 DOI: 10.1210/Jcem-47-6-1190  0.489
1978 Spiegel AM, Marx SJ, Brennan MF, Brown EM, Koehler JO, Aurbach GD. Urinary cAMP excretion during surgery: an index of successful parathyroidectomy in patients with primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 47: 537-42. PMID 233674 DOI: 10.1210/Jcem-47-3-537  0.578
1978 Spiegel AM, Doppman JL, Marx SJ, Brennan MF, Brown EM, Downs RW, Gardner DG, Attie M, Aurbach GD. Preoperative localization of abnormal parathyroid: neck massage versus arteriography and selective venous sampling. Annals of Internal Medicine. 89: 935-6. PMID 214001 DOI: 10.7326/0003-4819-89-6-935  0.535
1978 Spiegel A, Greene M, Magrath I, Balow J, Marx S, Aurbach GD. Hypercalcemia with suppressed parathyroid hormone in Burkitt's lymphoma. The American Journal of Medicine. 64: 691-5. PMID 206138 DOI: 10.1016/0002-9343(78)90592-2  0.564
1977 Marx SJ, Spiegel AM, Brown EM, Aurbach GD. Family studies in patients with primary parathyroid hyperplasia. The American Journal of Medicine. 62: 698-706. PMID 871127 DOI: 10.1016/0002-9343(77)90873-7  0.568
1977 Spiegel AM, Harrison HE, Marx SJ, Brown EM, Aurbach GD. Neonatal primary hyperparathyroidism with autosomal dominant inheritance. The Journal of Pediatrics. 90: 269-72. PMID 830920 DOI: 10.1016/S0022-3476(77)80649-5  0.51
1977 Spiegel AM, Downs RW, Aurbach GD. Guanosine 5', alpha-beta-methylene, triphosphate, a novel GTP analog, causes persistent activation of adenylate cyclase: evidence against pyrophosphorylation mechanism. Biochemical and Biophysical Research Communications. 76: 758-64. PMID 197925 DOI: 10.1016/0006-291X(77)91565-0  0.514
1977 Bilezikian JP, Spiegel AM, Gammon DE, Aurbach GD. The role of guanyl nucleotides in the expression on of catecholamine-responsive adenylate cyclase during maturation of the rat reticulocyte. Molecular Pharmacology. 13: 786-95. PMID 197394  0.431
1977 Bilezikian JP, Spiegel AM, Brown EM, Aurbach GD. Identification and persistence of beta adrenergic receptors during maturation of the rat reticulocyte. Molecular Pharmacology. 13: 775-85. PMID 197393  0.433
1976 Gardner JD, Aurbach GD, Spiegel AM, Brown EM. Receptor function and ion transport in turkey erythrocytes. Recent Progress in Hormone Research. 32: 567-95. PMID 785559 DOI: 10.1016/B978-0-12-571132-6.50031-2  0.525
1976 Spiegel AM, Gerner RH, Murphy DL, Aurbach GD. Lithium does not inhibit the parathyroid hormone-mediated rise in urinary cyclic AMP and phosphate in humans. The Journal of Clinical Endocrinology and Metabolism. 43: 1390-3. PMID 187615 DOI: 10.1210/Jcem-43-6-1390  0.559
1975 Spiegel AM, Marx SJ, Doppman JL, Beazley RM, Ketcham AS, Kasten B, Aurbach GD. Intrathyroidal parathyroid adenoma or hyperplasia. An occasionally overlooked cause of surgical failure in primary hyperparathyroidism. Jama. 234: 1029-33. PMID 1242409 DOI: 10.1001/Jama.1975.03260230029018  0.552
1975 Doppman JL, Marx SJ, Spiegel AM, Mallette LE, Wolfe DR, Aurbach GD, Geelhoed G. Treatment of hyperparathyroidism by percutaneous embolization of a mediastinal adenoma. Radiology. 115: 37-42. PMID 1118615 DOI: 10.1148/115.1.37  0.548
1975 Doppman JL, Mallette LE, Marx SJ, Monchik JM, Broadus A, Spiegel AM, Beazley R, Aurbach GD. The localization of abnormal mediastinal parathyroid glands. Radiology. 115: 31-6. PMID 1118614 DOI: 10.1148/115.1.31  0.553
1974 Marx SJ, Doppman JL, Spiegel AM, Wolfe D, Aurbach GD. Embolization of a mediastinal parathyroid adenoma. The Journal of Clinical Endocrinology and Metabolism. 39: 1110-4. PMID 4372246 DOI: 10.1210/Jcem-39-6-1110  0.562
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