Year |
Citation |
Score |
2020 |
Zhu Z, Yi F, Epplin MP, Liu D, Summer SL, Mizu R, Shaulsky G, XiangWei W, Tang W, Burger PB, Menaldino DS, Myers SJ, Liotta DC, Hansen KB, Yuan H, et al. Negative allosteric modulation of GluN1/GluN3 NMDA receptors. Neuropharmacology. 108117. PMID 32389749 DOI: 10.1016/J.Neuropharm.2020.108117 |
0.902 |
|
2020 |
Kayser S, Hansen JC, Staudt M, Moroz A, Larsen Y, Temperini P, Yi F, Syrenne JT, Krogsgaard-Larsen N, Iliadis S, Nielsen B, Hansen KB, Pickering DS, Bunch L. Stereoselective Synthesis of New (2,3)-3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid Analogues Utilizing a C(sp)-H Activation Strategy and Structure-Activity Relationship Studies at the Ionotropic Glutamate Receptors. Acs Chemical Neuroscience. PMID 32065744 DOI: 10.1021/Acschemneuro.0C00003 |
0.795 |
|
2020 |
Yi F, Rouzbeh N, Hansen KB, Xu Y, Fanger CM, Gordon E, Paschetto K, Menniti FS, Volkmann RA. PTC-174, a positive allosteric modulator of NMDA receptors containing GluN2C or GluN2D subunits. Neuropharmacology. 107971. PMID 31987864 DOI: 10.1016/J.Neuropharm.2020.107971 |
0.848 |
|
2020 |
Zhao F, Rouzbeh N, Hansen KB, Clausen RP. Improved synthetic route for the GluN2-specific NMDA receptor glycine site agonist AICP Tetrahedron Letters. 61: 151653. DOI: 10.1016/J.Tetlet.2020.151653 |
0.699 |
|
2019 |
Yi F, Bhattacharya S, Thompson CM, Traynelis SF, Hansen KB. Functional and pharmacological properties of triheteromeric GluN1/2B/2D NMDA receptors. The Journal of Physiology. PMID 31541561 DOI: 10.1113/Jp278168 |
0.866 |
|
2019 |
Poulie CBM, Alcaide A, Krell-Jørgensen M, Larsen Y, Astier E, Bjørn-Yoshimoto WE, Yi F, Syrenne JT, Storgaard M, Nielsen B, Frydenvang KA, Jensen AA, Hansen KB, Pickering DS, Bunch L. Design and Synthesis of 2,3- trans-Proline Analogues as Ligands for Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters. Acs Chemical Neuroscience. PMID 31124660 DOI: 10.1021/Acschemneuro.9B00205 |
0.776 |
|
2019 |
Sainas S, Temperini P, Farnsworth JC, Yi F, M Oslash Llerud S, Jensen A, Nielsen B, Passoni A, Kastrup JS, Hansen KB, Boschi D, Pickering DS, Clausen RP, Lolli ML. Use of the 4-Hydroxy-Triazole Moiety as a Bioisosteric Tool in the Development of Ionotropic Glutamate Receptor Ligands. Journal of Medicinal Chemistry. PMID 30943028 DOI: 10.1021/Acs.Jmedchem.8B01986 |
0.823 |
|
2019 |
Marwick KFM, Hansen KB, Skehel PA, Hardingham GE, Wyllie DJA. Functional assessment of triheteromeric NMDA receptors containing a human variant associated with epilepsy. The Journal of Physiology. PMID 30604514 DOI: 10.1113/Jp277292 |
0.71 |
|
2018 |
Bhattacharya S, Khatri A, Swanger SA, DiRaddo JO, Yi F, Hansen KB, Yuan H, Traynelis SF. Triheteromeric GluN1/GluN2A/GluN2C NMDARs with Unique Single-Channel Properties Are the Dominant Receptor Population in Cerebellar Granule Cells. Neuron. 99: 315-328.e5. PMID 30056832 DOI: 10.1016/J.Neuron.2018.06.010 |
0.849 |
|
2018 |
Hansen KB, Yi F, Perszyk RE, Furukawa H, Wollmuth LP, Gibb AJ, Traynelis SF. Structure, function, and allosteric modulation of NMDA receptors. The Journal of General Physiology. PMID 30037851 DOI: 10.1085/Jgp.201812032 |
0.896 |
|
2018 |
Yi F, Zachariassen LG, Dorsett KN, Hansen KB. Properties of triheteromeric NMDA receptors containing two distinct GluN1 isoforms. Molecular Pharmacology. PMID 29483146 DOI: 10.1124/Mol.117.111427 |
0.777 |
|
2018 |
Yi F, Hansen K. Activation of NMDA receptors and postsynaptic events Reactome - a Curated Knowledgebase of Biological Pathways. 67. DOI: 10.3180/R-Hsa-442755.4 |
0.66 |
|
2017 |
Gynther M, Proietti Silvestri I, Hansen JC, Hansen KB, Malm T, Ishchenko Y, Larsen Y, Han L, Kayser S, Auriola S, Petsalo A, Nielsen B, Pickering DS, Bunch L. Augmentation of Anticancer Drug Efficacy in Murine Hepatocellular Carcinoma Cells by a Peripherally Acting Competitive N-Methyl-d-aspartate (NMDA) Receptor Antagonist. Journal of Medicinal Chemistry. 60: 9885-9904. PMID 29205034 DOI: 10.1021/Acs.Jmedchem.7B01624 |
0.594 |
|
2017 |
Yi F, Traynelis SF, Hansen KB. Selective Cell-Surface Expression of Triheteromeric NMDA Receptors. Methods in Molecular Biology (Clifton, N.J.). 1677: 145-162. PMID 28986871 DOI: 10.1007/978-1-4939-7321-7_7 |
0.863 |
|
2017 |
Hansen KB, Yi F, Perszyk RE, Menniti FS, Traynelis SF. NMDA Receptors in the Central Nervous System. Methods in Molecular Biology (Clifton, N.J.). 1677: 1-80. PMID 28986865 DOI: 10.1007/978-1-4939-7321-7_1 |
0.891 |
|
2017 |
Lind GE, Mou TC, Tamborini L, Pomper MG, De Micheli C, Conti P, Pinto A, Hansen KB. Structural basis of subunit selectivity for competitive NMDA receptor antagonists with preference for GluN2A over GluN2B subunits. Proceedings of the National Academy of Sciences of the United States of America. PMID 28760974 DOI: 10.1073/Pnas.1707752114 |
0.673 |
|
2017 |
Jessen M, Frederiksen K, Yi F, Clausen RP, Hansen KB, Brauner-Osborne H, Kilburn P, Damholt A. Identification of AICP as a GluN2C-selective NMDA receptor superagonist at the GluN1 glycine site. Molecular Pharmacology. PMID 28588066 DOI: 10.1124/Mol.117.108944 |
0.836 |
|
2017 |
Maolanon A, Risgaard R, Wang SY, Snoep Y, Papangelis A, Yi F, Holley D, Barslund AF, Svenstrup N, Hansen KB, Clausen RP. Subtype-specific agonists for NMDA receptor glycine binding sites. Acs Chemical Neuroscience. PMID 28514141 DOI: 10.1021/Acschemneuro.7B00117 |
0.827 |
|
2017 |
Sun W, Hansen KB, Jahr CE. Allosteric Interactions between NMDA Receptor Subunits Shape the Developmental Shift in Channel Properties. Neuron. 94: 58-64.e3. PMID 28384476 DOI: 10.1016/J.Neuron.2017.03.018 |
0.759 |
|
2016 |
Tamborini L, Chen Y, Foss CA, Pinto A, Horti AG, Traynelis SF, De Micheli C, Mease RC, Hansen KB, Conti P, Pomper MG. Development of Radiolabeled Ligands Targeting the Glutamate Binding Site of the N-Methyl-d-aspartate Receptor as Potential Imaging Agents for Brain. Journal of Medicinal Chemistry. 59: 11110-11119. PMID 28002957 DOI: 10.1021/Acs.Jmedchem.6B01344 |
0.635 |
|
2016 |
Yi F, Mou TC, Dorsett KN, Volkmann RA, Menniti FS, Sprang SR, Hansen KB. Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors. Neuron. PMID 27618671 DOI: 10.1016/J.Neuron.2016.08.014 |
0.826 |
|
2016 |
Cheriyan J, Balsara RD, Hansen KB, Castellino FJ. Pharmacology of triheteromeric N-Methyl-d-Aspartate Receptors. Neuroscience Letters. 617: 240-246. PMID 26917100 DOI: 10.1016/J.Neulet.2016.02.032 |
0.602 |
|
2015 |
Kristensen AS, Hansen KB, Naur P, Olsen L, Kurtkaya NL, Dravid SM, Kvist T, Yi F, Pohlsgaard J, Clausen RP, Gajhede M, Kastrup JS, Traynelis SF. Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors. Molecular Pharmacology. PMID 26661043 DOI: 10.1124/Mol.115.100909 |
0.86 |
|
2015 |
Zimmerman SS, Khatri A, Garnier-Amblard EC, Mullasseril P, Kurtkaya NL, Gyoneva S, Hansen KB, Traynelis SF, Liotta DC. Correction to "Design, synthesis, and structure-activity relationship of a novel series of GluN2C-selective potentiators". Journal of Medicinal Chemistry. 58: 2862. PMID 25738634 DOI: 10.1021/Acs.Jmedchem.5B00199 |
0.753 |
|
2015 |
Poulsen MH, Andersen J, Christensen R, Hansen KB, Traynelis SF, Strømgaard K, Kristensen AS. Binding of ArgTX-636 in the NMDA receptor ion channel. Journal of Molecular Biology. 427: 176-89. PMID 24862283 DOI: 10.1016/J.Jmb.2014.05.017 |
0.799 |
|
2014 |
Hansen KB, Traynelis SF. Glutamate receptors: mechanistic twists and turns. Nature Chemical Biology. 10: 698-9. PMID 25271345 DOI: 10.1038/Nchembio.1614 |
0.776 |
|
2014 |
Khatri A, Burger PB, Swanger SA, Hansen KB, Zimmerman S, Karakas E, Liotta DC, Furukawa H, Snyder JP, Traynelis SF. Structural determinants and mechanism of action of a GluN2C-selective NMDA receptor positive allosteric modulator. Molecular Pharmacology. 86: 548-60. PMID 25205677 DOI: 10.1124/Mol.114.094516 |
0.892 |
|
2014 |
Hansen KB, Ogden KK, Yuan H, Traynelis SF. Distinct functional and pharmacological properties of Triheteromeric GluN1/GluN2A/GluN2B NMDA receptors. Neuron. 81: 1084-96. PMID 24607230 DOI: 10.1016/J.Neuron.2014.01.035 |
0.906 |
|
2014 |
Zimmerman SS, Khatri A, Garnier-Amblard EC, Mullasseril P, Kurtkaya NL, Gyoneva S, Hansen KB, Traynelis SF, Liotta DC. Design, synthesis, and structure-activity relationship of a novel series of GluN2C-selective potentiators. Journal of Medicinal Chemistry. 57: 2334-56. PMID 24512267 DOI: 10.1021/Jm401695D |
0.883 |
|
2014 |
Yuan H, Hansen KB, Zhang J, Pierson TM, Markello TC, Fajardo KV, Holloman CM, Golas G, Adams DR, Boerkoel CF, Gahl WA, Traynelis SF. Functional analysis of a de novo GRIN2A missense mutation associated with early-onset epileptic encephalopathy. Nature Communications. 5: 3251. PMID 24504326 DOI: 10.1038/Ncomms4251 |
0.761 |
|
2014 |
Ogden KK, Yuan H, Hansen KB, Zhang J, Gibb AJ, Traynelis SF. A Human Mutation in the M4 Helix of GluN2A Accelerates Forward Gating Transitions in NMDA Receptors Biophysical Journal. 106: 150a. DOI: 10.1016/J.Bpj.2013.11.863 |
0.855 |
|
2013 |
Kvist T, Steffensen TB, Greenwood JR, Mehrzad Tabrizi F, Hansen KB, Gajhede M, Pickering DS, Traynelis SF, Kastrup JS, Bräuner-Osborne H. Crystal structure and pharmacological characterization of a novel N-methyl-D-aspartate (NMDA) receptor antagonist at the GluN1 glycine binding site. The Journal of Biological Chemistry. 288: 33124-35. PMID 24072709 DOI: 10.1074/Jbc.M113.480210 |
0.784 |
|
2013 |
Kvist T, Greenwood JR, Hansen KB, Traynelis SF, Bräuner-Osborne H. Structure-based discovery of antagonists for GluN3-containing N-methyl-D-aspartate receptors. Neuropharmacology. 75: 324-36. PMID 23973313 DOI: 10.1016/J.Neuropharm.2013.08.003 |
0.82 |
|
2013 |
Hansen KB, Tajima N, Risgaard R, Perszyk RE, Jørgensen L, Vance KM, Ogden KK, Clausen RP, Furukawa H, Traynelis SF. Structural determinants of agonist efficacy at the glutamate binding site of N-methyl-D-aspartate receptors. Molecular Pharmacology. 84: 114-27. PMID 23625947 DOI: 10.1124/Mol.113.085803 |
0.878 |
|
2013 |
Risgaard R, Nielsen SD, Hansen KB, Jensen CM, Nielsen B, Traynelis SF, Clausen RP. Development of 2'-substituted (2S,1'R,2'S)-2-(carboxycyclopropyl)glycine analogues as potent N-methyl-d-aspartic acid receptor agonists. Journal of Medicinal Chemistry. 56: 4071-81. PMID 23614571 DOI: 10.1021/Jm400346A |
0.8 |
|
2013 |
Vance KM, Hansen KB, Traynelis SF. Modal gating of GluN1/GluN2D NMDA receptors. Neuropharmacology. 71: 184-90. PMID 23578394 DOI: 10.1016/J.Neuropharm.2013.03.018 |
0.881 |
|
2012 |
Vance KM, Hansen KB, Traynelis SF. GluN1 splice variant control of GluN1/GluN2D NMDA receptors. The Journal of Physiology. 590: 3857-75. PMID 22641781 DOI: 10.1113/Jphysiol.2012.234062 |
0.897 |
|
2012 |
Hansen KB, Ogden KK, Traynelis SF. Subunit-selective allosteric inhibition of glycine binding to NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6197-208. PMID 22553026 DOI: 10.1523/Jneurosci.5757-11.2012 |
0.881 |
|
2012 |
Hedegaard M, Hansen KB, Andersen KT, Bräuner-Osborne H, Traynelis SF. Molecular pharmacology of human NMDA receptors. Neurochemistry International. 61: 601-9. PMID 22197913 DOI: 10.1016/J.Neuint.2011.11.016 |
0.819 |
|
2012 |
Kristensen AS, Poulsen MH, Jensen CB, Andersen J, Hansen K, Strømgaard K. Molecular Determinants for Subtype-Selective Ion Channel Block of NMDA Receptors by Argiotoxin Analogs Biophysical Journal. 102: 524a. DOI: 10.1016/J.Bpj.2011.11.2866 |
0.844 |
|
2012 |
Hansen KB, Wollmuth LP, Traynelis SF. Structure-function correlates of glutamate-gated ion channels Comprehensive Biophysics. 6: 4-30. DOI: 10.1016/B978-0-12-374920-8.00611-1 |
0.574 |
|
2011 |
Acker TM, Yuan H, Hansen KB, Vance KM, Ogden KK, Jensen HS, Burger PB, Mullasseril P, Snyder JP, Liotta DC, Traynelis SF. Mechanism for noncompetitive inhibition by novel GluN2C/D N-methyl-D-aspartate receptor subunit-selective modulators. Molecular Pharmacology. 80: 782-95. PMID 21807990 DOI: 10.1124/Mol.111.073239 |
0.876 |
|
2011 |
Hansen KB, Traynelis SF. How glutamate receptor subunits mix and match: details uncovered. Neuron. 71: 198-200. PMID 21791278 DOI: 10.1016/J.Neuron.2011.07.008 |
0.766 |
|
2011 |
Hansen KB, Traynelis SF. Structural and mechanistic determinants of a novel site for noncompetitive inhibition of GluN2D-containing NMDA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 3650-61. PMID 21389220 DOI: 10.1523/Jneurosci.5565-10.2011 |
0.819 |
|
2010 |
Mullasseril P, Hansen KB, Vance KM, Ogden KK, Yuan H, Kurtkaya NL, Santangelo R, Orr AG, Le P, Vellano KM, Liotta DC, Traynelis SF. A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors. Nature Communications. 1: 90. PMID 20981015 DOI: 10.1038/Ncomms1085 |
0.885 |
|
2010 |
Risgaard R, Hansen KB, Clausen RP. Partial agonists and subunit selectivity at NMDA receptors. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 13910-8. PMID 20945316 DOI: 10.1002/Chem.201001366 |
0.741 |
|
2010 |
Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R. Glutamate receptor ion channels: structure, regulation, and function. Pharmacological Reviews. 62: 405-96. PMID 20716669 DOI: 10.1124/Pr.109.002451 |
0.875 |
|
2010 |
Mosley CA, Acker TM, Hansen KB, Mullasseril P, Andersen KT, Le P, Vellano KM, Bräuner-Osborne H, Liotta DC, Traynelis SF. Quinazolin-4-one derivatives: A novel class of noncompetitive NR2C/D subunit-selective N-methyl-D-aspartate receptor antagonists. Journal of Medicinal Chemistry. 53: 5476-90. PMID 20684595 DOI: 10.1021/Jm100027P |
0.822 |
|
2010 |
Conti P, Pinto A, Tamborini L, Madsen U, Nielsen B, Bräuner-Osborne H, Hansen KB, Landucci E, Pellegrini-Giampietro DE, De Sarro G, Donato Di Paola E, De Micheli C. Novel 3-carboxy- and 3-phosphonopyrazoline amino acids as potent and selective NMDA receptor antagonists: design, synthesis, and pharmacological characterization. Chemmedchem. 5: 1465-75. PMID 20665761 DOI: 10.1002/Cmdc.201000184 |
0.685 |
|
2010 |
Hansen KB, Furukawa H, Traynelis SF. Control of assembly and function of glutamate receptors by the amino-terminal domain. Molecular Pharmacology. 78: 535-49. PMID 20660085 DOI: 10.1124/Mol.110.067157 |
0.785 |
|
2010 |
Lolli ML, Giordano C, Pickering DS, Rolando B, Hansen KB, Foti A, Contreras-Sanz A, Amir A, Fruttero R, Gasco A, Nielsen B, Johansen TN. 4-hydroxy-1,2,5-oxadiazol-3-yl moiety as bioisoster of the carboxy function. Synthesis, ionization constants, and molecular pharmacological characterization at ionotropic glutamate receptors of compounds related to glutamate and its homologues. Journal of Medicinal Chemistry. 53: 4110-8. PMID 20408529 DOI: 10.1021/Jm1001452 |
0.674 |
|
2010 |
Hansen KB, Mullasseril P, Dawit S, Kurtkaya NL, Yuan H, Vance KM, Orr AG, Kvist T, Ogden KK, Le P, Vellano KM, Lewis I, Kurtkaya S, Du Y, Qui M, et al. Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists. The Journal of Pharmacology and Experimental Therapeutics. 333: 650-62. PMID 20197375 DOI: 10.1124/Jpet.110.166256 |
0.882 |
|
2010 |
Andersen J, Olsen L, Hansen KB, Taboureau O, Jørgensen FS, Jørgensen AM, Bang-Andersen B, Egebjerg J, Strømgaard K, Kristensen AS. Mutational mapping and modeling of the binding site for (S)-citalopram in the human serotonin transporter. The Journal of Biological Chemistry. 285: 2051-63. PMID 19892699 DOI: 10.1074/Jbc.M109.072587 |
0.61 |
|
2010 |
Hansen KB, Burger P, Vance KM, Snyder JP, Clausen RP, Traynelis SF. Subunit-Specific Activation of NMDA Receptors Biophysical Journal. 98: 525a-526a. DOI: 10.1016/J.Bpj.2009.12.2854 |
0.898 |
|
2010 |
Vance KM, Hansen KB, Ogden KK, Traynelis SF. Activation of Recombinant Rat GluN1/gluN2D NMDA Receptors Biophysical Journal. 98: 525a. DOI: 10.1016/J.Bpj.2009.12.2851 |
0.879 |
|
2009 |
Yuan H, Hansen KB, Vance KM, Ogden KK, Traynelis SF. Control of NMDA receptor function by the NR2 subunit amino-terminal domain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12045-58. PMID 19793963 DOI: 10.1523/Jneurosci.1365-09.2009 |
0.887 |
|
2009 |
Zhong H, Hansen KB, Boyle NJ, Han K, Muske G, Huang X, Egebjerg J, Sánchez C. An allosteric binding site at the human serotonin transporter mediates the inhibition of escitalopram by R-citalopram: kinetic binding studies with the ALI/VFL-SI/TT mutant. Neuroscience Letters. 462: 207-12. PMID 19616061 DOI: 10.1016/J.Neulet.2009.07.030 |
0.327 |
|
2009 |
Hansen KB, Bräuner-Osborne H. Xenopus oocyte electrophysiology in GPCR drug discovery. Methods in Molecular Biology (Clifton, N.J.). 552: 343-57. PMID 19513662 DOI: 10.1007/978-1-60327-317-6_25 |
0.402 |
|
2009 |
Andersen J, Taboureau O, Hansen KB, Olsen L, Egebjerg J, Strømgaard K, Kristensen AS. Location of the antidepressant binding site in the serotonin transporter: importance of Ser-438 in recognition of citalopram and tricyclic antidepressants. The Journal of Biological Chemistry. 284: 10276-84. PMID 19213730 DOI: 10.1074/Jbc.M806907200 |
0.606 |
|
2009 |
Hansen KB, Naur P, Kurtkaya NL, Kristensen AS, Gajhede M, Kastrup JS, Traynelis SF. Modulation of the dimer interface at ionotropic glutamate-like receptor delta2 by D-serine and extracellular calcium. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 907-17. PMID 19176800 DOI: 10.1523/Jneurosci.4081-08.2009 |
0.797 |
|
2009 |
Sivaprakasam M, Hansen KB, David O, Nielsen B, Traynelis SF, Clausen RP, Couty F, Bunch L. Stereocontrolled synthesis and pharmacological evaluation of azetidine-2,3-dicarboxylic acids at NMDA receptors. Chemmedchem. 4: 110-7. PMID 19009584 DOI: 10.1002/Cmdc.200800226 |
0.701 |
|
2008 |
Clausen RP, Christensen C, Hansen KB, Greenwood JR, Jørgensen L, Micale N, Madsen JC, Nielsen B, Egebjerg J, Bräuner-Osborne H, Traynelis SF, Kristensen JL. N-Hydroxypyrazolyl glycine derivatives as selective N-methyl-D-aspartic acid receptor ligands. Journal of Medicinal Chemistry. 51: 4179-87. PMID 18578474 DOI: 10.1021/Jm800025E |
0.791 |
|
2008 |
Hansen KB, Bräuner-Osborne H, Egebjerg J. Pharmacological characterization of ligands at recombinant NMDA receptor subtypes by electrophysiological recordings and intracellular calcium measurements. Combinatorial Chemistry & High Throughput Screening. 11: 304-15. PMID 18473740 DOI: 10.2174/138620708784246040 |
0.693 |
|
2008 |
Wellendorph P, Hansen KB, Christiansen B, Burhenne N, Balsgaard A, Greenwood JR, Walter B, Schmale H, Egebjerg J, Bräuner-Osborne H. Characterization of GPRC6A: a 7TM receptor activated by L-alpha-amino acids and positively modulated by divalent cations Fundamental & Clinical Pharmacology. 22: 25-25. DOI: 10.1111/J.1472-8206.2008.00591.X |
0.426 |
|
2008 |
Yuan H, Geballe MT, Hansen KB, Traynelis SF. Structure and function of the NMDA receptor Structural and Functional Organization of the Synapse. 289-316. DOI: 10.1007/978-0-387-77232-5_11 |
0.838 |
|
2007 |
Naur P, Hansen KB, Kristensen AS, Dravid SM, Pickering DS, Olsen L, Vestergaard B, Egebjerg J, Gajhede M, Traynelis SF, Kastrup JS. Ionotropic glutamate-like receptor delta2 binds D-serine and glycine. Proceedings of the National Academy of Sciences of the United States of America. 104: 14116-21. PMID 17715062 DOI: 10.1073/Pnas.0703718104 |
0.846 |
|
2007 |
Erreger K, Geballe MT, Kristensen A, Chen PE, Hansen KB, Lee CJ, Yuan H, Le P, Lyuboslavsky PN, Micale N, Jørgensen L, Clausen RP, Wyllie DJ, Snyder JP, Traynelis SF. Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors. Molecular Pharmacology. 72: 907-20. PMID 17622578 DOI: 10.1124/Mol.107.037333 |
0.888 |
|
2007 |
Hansen KB, Yuan H, Traynelis SF. Structural aspects of AMPA receptor activation, desensitization and deactivation. Current Opinion in Neurobiology. 17: 281-8. PMID 17419047 DOI: 10.1016/J.Conb.2007.03.014 |
0.836 |
|
2007 |
Jørgensen CG, Clausen RP, Hansen KB, Bräuner-Osborne H, Nielsen B, Metzler B, Metzler BB, Kehler J, Krogsgaard-Larsen P, Madsen U. Synthesis and pharmacology of glutamate receptor ligands: new isothiazole analogues of ibotenic acid. Organic & Biomolecular Chemistry. 5: 463-71. PMID 17340770 DOI: 10.1039/B615162K |
0.653 |
|
2007 |
Christiansen B, Hansen KB, Wellendorph P, Bräuner-Osborne H. Pharmacological characterization of mouse GPRC6A, an L-alpha-amino-acid receptor modulated by divalent cations. British Journal of Pharmacology. 150: 798-807. PMID 17245368 DOI: 10.1038/Sj.Bjp.0707121 |
0.459 |
|
2005 |
Conti P, De Amici M, Grazioso G, Roda G, Pinto A, Hansen KB, Nielsen B, Madsen U, Bräuner-Osborne H, Egebjerg J, Vestri V, Pellegrini-Giampietro DE, Sibille P, Acher FC, De Micheli C. Synthesis, binding affinity at glutamic acid receptors, neuroprotective effects, and molecular modeling investigation of novel dihydroisoxazole amino acids. Journal of Medicinal Chemistry. 48: 6315-25. PMID 16190758 DOI: 10.1021/Jm0504499 |
0.679 |
|
2005 |
Hansen KB, Clausen RP, Bjerrum EJ, Bechmann C, Greenwood JR, Christensen C, Kristensen JL, Egebjerg J, Bräuner-Osborne H. Tweaking agonist efficacy at N-methyl-D-aspartate receptors by site-directed mutagenesis. Molecular Pharmacology. 68: 1510-23. PMID 16131614 DOI: 10.1124/Mol.105.014795 |
0.606 |
|
2005 |
Wellendorph P, Hansen KB, Balsgaard A, Greenwood JR, Egebjerg J, Bräuner-Osborne H. Deorphanization of GPRC6A: a promiscuous L-alpha-amino acid receptor with preference for basic amino acids. Molecular Pharmacology. 67: 589-97. PMID 15576628 DOI: 10.1124/Mol.104.007559 |
0.547 |
|
2004 |
Clausen RP, Hansen KB, Calà P, Nielsen B, Greenwood JR, Begtrup M, Egebjerg J, Bräuner-Osborne H. The respective N-hydroxypyrazole analogues of the classical glutamate receptor ligands ibotenic acid and (RS)-2-amino-2-(3-hydroxy-5-methyl-4-isoxazolyl)acetic acid. European Journal of Pharmacology. 499: 35-44. PMID 15363949 DOI: 10.1016/J.Ejphar.2004.07.049 |
0.629 |
|
2003 |
Brehm L, Greenwood JR, Hansen KB, Nielsen B, Egebjerg J, Stensbøl TB, Bräuner-Osborne H, Sløk FA, Kronborg TT, Krogsgaard-Larsen P. (S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic acid, a potent and selective agonist at the GluR5 subtype of ionotropic glutamate receptors. Synthesis, modeling, and molecular pharmacology. Journal of Medicinal Chemistry. 46: 1350-8. PMID 12672235 DOI: 10.1021/Jm0204441 |
0.651 |
|
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