Janet Rossant, Ph.D. - Publications

Affiliations: 
Sick Kids 
Area:
Stem cell research, Molecular genetics, Developmental biology
Website:
http://www.sickkids.ca/research/rossant/

208 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Huang D, Guo G, Yuan P, Ralston A, Sun L, Huss M, Mistri T, Pinello L, Ng HH, Yuan G, Ji J, Rossant J, Robson P, Han X. The role of Cdx2 as a lineage specific transcriptional repressor for pluripotent network during the first developmental cell lineage segregation. Scientific Reports. 7: 17156. PMID 29214996 DOI: 10.1038/s41598-017-16009-w  0.4
2016 Lee CQ, Gardner L, Turco M, Zhao N, Murray MJ, Coleman N, Rossant J, Hemberger M, Moffett A. What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast. Stem Cell Reports. 6: 257-272. PMID 26862703 DOI: 10.1016/j.stemcr.2016.01.006  0.48
2016 Frankenberg SR, de Barros FR, Rossant J, Renfree MB. The mammalian blastocyst. Wiley Interdisciplinary Reviews. Developmental Biology. PMID 26799266 DOI: 10.1002/wdev.220  0.48
2016 Rossant J. Making the Mouse Blastocyst: Past, Present, and Future Current Topics in Developmental Biology. DOI: 10.1016/bs.ctdb.2015.11.015  0.48
2015 Kurmann AA, Serra M, Hawkins F, Rankin SA, Mori M, Astapova I, Ullas S, Lin S, Bilodeau M, Rossant J, Jean JC, Ikonomou L, Deterding RR, Shannon JM, Zorn AM, et al. Regeneration of Thyroid Function by Transplantation of Differentiated Pluripotent Stem Cells. Cell Stem Cell. 17: 527-42. PMID 26593959 DOI: 10.1016/j.stem.2015.09.004  0.48
2015 De Los Angeles A, Ferrari F, Xi R, Fujiwara Y, Benvenisty N, Deng H, Hochedlinger K, Jaenisch R, Lee S, Leitch HG, Lensch MW, Lujan E, Pei D, Rossant J, Wernig M, et al. Hallmarks of pluripotency. Nature. 525: 469-78. PMID 26399828 DOI: 10.1038/nature15515  0.48
2015 Li L, Song L, Liu C, Chen J, Peng G, Wang R, Liu P, Tang K, Rossant J, Jing N. Ectodermal progenitors derived from epiblast stem cells by inhibition of Nodal signaling. Journal of Molecular Cell Biology. PMID 25990320 DOI: 10.1093/jmcb/mjv030  0.48
2015 Shojaie S, Ermini L, Ackerley C, Wang J, Chin S, Yeganeh B, Bilodeau M, Sambi M, Rogers I, Rossant J, Bear CE, Post M. Acellular lung scaffolds direct differentiation of endoderm to functional airway epithelial cells: requirement of matrix-bound HS proteoglycans. Stem Cell Reports. 4: 419-30. PMID 25660407 DOI: 10.1016/j.stemcr.2015.01.004  0.48
2015 Wong AP, Chin S, Xia S, Garner J, Bear CE, Rossant J. Efficient generation of functional CFTR-expressing airway epithelial cells from human pluripotent stem cells. Nature Protocols. 10: 363-81. PMID 25654755 DOI: 10.1038/nprot.2015.021  0.48
2015 Rossant J. Mouse and human blastocyst-derived stem cells: vive les differences. Development (Cambridge, England). 142: 9-12. PMID 25516964 DOI: 10.1242/dev.115451  0.48
2014 Kunath T, Yamanaka Y, Detmar J, MacPhee D, Caniggia I, Rossant J, Jurisicova A. Developmental differences in the expression of FGF receptors between human and mouse embryos. Placenta. 35: 1079-88. PMID 25443433 DOI: 10.1016/j.placenta.2014.09.008  0.48
2014 McDonald AC, Rossant J. Gut endoderm takes flight from the wings of mesoderm. Nature Cell Biology. 16: 1128-9. PMID 25434463 DOI: 10.1038/ncb3077  0.48
2014 McDonald AC, Biechele S, Rossant J, Stanford WL. Sox17-mediated XEN cell conversion identifies dynamic networks controlling cell-fate decisions in embryo-derived stem cells. Cell Reports. 9: 780-93. PMID 25373912 DOI: 10.1016/j.celrep.2014.09.026  0.48
2014 Bilodeau M, Shojaie S, Ackerley C, Post M, Rossant J. Identification of a proximal progenitor population from murine fetal lungs with clonogenic and multilineage differentiation potential. Stem Cell Reports. 3: 634-49. PMID 25358791 DOI: 10.1016/j.stemcr.2014.07.010  0.48
2014 Rayon T, Menchero S, Nieto A, Xenopoulos P, Crespo M, Cockburn K, Cañon S, Sasaki H, Hadjantonakis AK, de la Pompa JL, Rossant J, Manzanares M. Notch and hippo converge on Cdx2 to specify the trophectoderm lineage in the mouse blastocyst. Developmental Cell. 30: 410-22. PMID 25127056 DOI: 10.1016/j.devcel.2014.06.019  0.48
2014 Rossant J. A trusted voice for stem cell research. Stem Cell Reports. 2: 749-50. PMID 24936462 DOI: 10.1016/j.stemcr.2014.05.014  0.48
2014 Kabiri Z, Greicius G, Madan B, Biechele S, Zhong Z, Zaribafzadeh H, Edison, Aliyev J, Wu Y, Bunte R, Williams BO, Rossant J, Virshup DM. Stroma provides an intestinal stem cell niche in the absence of epithelial Wnts. Development (Cambridge, England). 141: 2206-15. PMID 24821987 DOI: 10.1242/dev.104976  0.48
2014 Rossant J. Genes for regeneration. Elife. 3: e02517. PMID 24737866 DOI: 10.7554/eLife.02517  0.48
2014 Saccone V, Consalvi S, Giordani L, Mozzetta C, Barozzi I, Sandoná M, Ryan T, Rojas-Muñoz A, Madaro L, Fasanaro P, Borsellino G, De Bardi M, Frigè G, Termanini A, Sun X, ... Rossant J, et al. HDAC-regulated myomiRs control BAF60 variant exchange and direct the functional phenotype of fibro-adipogenic progenitors in dystrophic muscles. Genes & Development. 28: 841-57. PMID 24682306 DOI: 10.1101/gad.234468.113  0.48
2014 Chen F, Guo R, Itoh S, Moreno L, Rosenthal E, Zappitelli T, Zirngibl RA, Flenniken A, Cole W, Grynpas M, Osborne LR, Vogel W, Adamson L, Rossant J, Aubin JE. First mouse model for combined osteogenesis imperfecta and Ehlers-Danlos syndrome. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 1412-23. PMID 24443344 DOI: 10.1002/jbmr.2177  0.48
2014 Posfai E, Tam OH, Rossant J. Mechanisms of pluripotency in vivo and in vitro. Current Topics in Developmental Biology. 107: 1-37. PMID 24439801 DOI: 10.1016/B978-0-12-416022-4.00001-9  0.48
2014 Kotton DN, Rossant J. Modeling pulmonary alveolar proteinosis with induced pluripotent stem cells. American Journal of Respiratory and Critical Care Medicine. 189: 124-6. PMID 24428646 DOI: 10.1164/rccm.201312-2122ED  0.48
2013 Biechele S, Adissu HA, Cox BJ, Rossant J. Zygotic Porcn paternal allele deletion in mice to model human focal dermal hypoplasia. Plos One. 8: e79139. PMID 24223895 DOI: 10.1371/journal.pone.0079139  0.48
2013 Li L, Liu C, Biechele S, Zhu Q, Song L, Lanner F, Jing N, Rossant J. Location of transient ectodermal progenitor potential in mouse development. Development (Cambridge, England). 140: 4533-43. PMID 24131634 DOI: 10.1242/dev.092866  0.48
2013 Anderson NM, Javadi M, Berndl E, Berberovic Z, Bailey ML, Huang K, Flenniken AM, Osborne LR, Adamson SL, Rossant J, Carter-Su C, Wang C, McNagny KM, Paulson RF, Minden MD, et al. Enu mutagenesis identifies a novel platelet phenotype in a loss-of-function Jak2 allele. Plos One. 8: e75472. PMID 24086539 DOI: 10.1371/journal.pone.0075472  0.48
2013 Rossant J. Making a knockout mouse: From stem cells to embryos. Nature Cell Biology. 15: 1133. PMID 24084859 DOI: 10.1038/ncb2850  0.48
2013 Bernstein A, Rossant J. Anthony James Pawson (1952-2013). Nature. 501: 168. PMID 24025833 DOI: 10.1038/501168a  0.48
2013 Kelsey L, Flenniken AM, Qu D, Funnell AP, Pearson R, Zhou YQ, Voronina I, Berberovic Z, Wood G, Newbigging S, Weiss ES, Wong M, Quach I, Yeh SY, Deshwar AR, ... ... Rossant J, et al. ENU-induced mutation in the DNA-binding domain of KLF3 reveals important roles for KLF3 in cardiovascular development and function in mice. Plos Genetics. 9: e1003612. PMID 23874215 DOI: 10.1371/journal.pgen.1003612  0.48
2013 Cockburn K, Biechele S, Garner J, Rossant J. The Hippo pathway member Nf2 is required for inner cell mass specification. Current Biology : Cb. 23: 1195-201. PMID 23791728 DOI: 10.1016/j.cub.2013.05.044  0.48
2013 Biechele S, Cockburn K, Lanner F, Cox BJ, Rossant J. Porcn-dependent Wnt signaling is not required prior to mouse gastrulation. Development (Cambridge, England). 140: 2961-71. PMID 23760955 DOI: 10.1242/dev.094458  0.48
2013 Morrisey EE, Cardoso WV, Lane RH, Rabinovitch M, Abman SH, Ai X, Albertine KH, Bland RD, Chapman HA, Checkley W, Epstein JA, Kintner CR, Kumar M, Minoo P, Mariani TJ, ... ... Rossant J, et al. Molecular determinants of lung development. Annals of the American Thoracic Society. 10: S12-6. PMID 23607856 DOI: 10.1513/AnnalsATS.201207-036OT  0.48
2013 Adams D, Baldock R, Bhattacharya S, Copp AJ, Dickinson M, Greene ND, Henkelman M, Justice M, Mohun T, Murray SA, Pauws E, Raess M, Rossant J, Weaver T, West D. Bloomsbury report on mouse embryo phenotyping: recommendations from the IMPC workshop on embryonic lethal screening. Disease Models & Mechanisms. 6: 571-9. PMID 23519032 DOI: 10.1242/dmm.011833  0.48
2013 Findlay GM, Smith MJ, Lanner F, Hsiung MS, Gish GD, Petsalaki E, Cockburn K, Kaneko T, Huang H, Bagshaw RD, Ketela T, Tucholska M, Taylor L, Bowtell DD, Moffat J, ... ... Rossant J, et al. Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate. Cell. 152: 1008-20. PMID 23452850 DOI: 10.1016/j.cell.2013.01.056  0.48
2013 Adams D, Baldock R, Bhattacharya S, Copp AJ, Dickinson M, Greene NDE, Henkelman M, Justice M, Mohun T, Murray SA, Pauws E, Raess M, Rossant J, Weaver T, West D. Bloomsbury report on mouse embryo phenotyping: Recommendations from the IMPC workshop on embryonic lethal screening (DMM Disease Models and Mechanisms 6, (571-579)) Dmm Disease Models and Mechanisms. 6: 1049. DOI: 10.1242/dmm.012898  0.48
2013 Kunath T, Rossant J. Stem Cells in Extraembryonic Lineages Handbook of Stem Cells. 2: 481-492. DOI: 10.1016/B978-0-12-385942-6.00042-1  0.48
2013 Rossant J. Embryonic Stem Cells in Perspective Handbook of Stem Cells. 1: 27-28. DOI: 10.1016/B978-0-12-385942-6.00004-4  0.48
2012 Rossant J, Mummery C. NOBEL 2012 Physiology or medicine: Mature cells can be rejuvenated. Nature. 492: 56. PMID 23222608 DOI: 10.1038/492056a  0.48
2012 Hirate Y, Cockburn K, Rossant J, Sasaki H. Tead4 is constitutively nuclear, while nuclear vs. cytoplasmic Yap distribution is regulated in preimplantation mouse embryos. Proceedings of the National Academy of Sciences of the United States of America. 109: E3389-90; author rep. PMID 23169672 DOI: 10.1073/pnas.1211810109  0.48
2012 Stephenson RO, Rossant J, Tam PP. Intercellular interactions, position, and polarity in establishing blastocyst cell lineages and embryonic axes. Cold Spring Harbor Perspectives in Biology. 4. PMID 23125013 DOI: 10.1101/cshperspect.a008235  0.48
2012 Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, ... ... Rossant J, et al. The mammalian gene function resource: the International Knockout Mouse Consortium. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 580-6. PMID 22968824 DOI: 10.1007/s00335-012-9422-2  0.48
2012 Rossant J. Profile of Janet Rossant. Interview by Kristie Nybo. Biotechniques. 53: 129. PMID 22963472 DOI: 10.2144/000113918  0.48
2012 Wong AP, Bear CE, Chin S, Pasceri P, Thompson TO, Huan LJ, Ratjen F, Ellis J, Rossant J. Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein. Nature Biotechnology. 30: 876-82. PMID 22922672 DOI: 10.1038/nbt.2328  0.48
2012 Blanpain C, Daley GQ, Hochedlinger K, Passegué E, Rossant J, Yamanaka S. Stem cells assessed. Nature Reviews. Molecular Cell Biology. 13: 471-6. PMID 22678486 DOI: 10.1038/nrm3371  0.48
2012 Owen C, Chen F, Flenniken AM, Osborne LR, Ichikawa S, Adamson SL, Rossant J, Aubin JE. A novel Phex mutation in a new mouse model of hypophosphatemic rickets. Journal of Cellular Biochemistry. 113: 2432-41. PMID 22573557 DOI: 10.1002/jcb.24115  0.48
2012 Rugg-Gunn PJ, Cox BJ, Lanner F, Sharma P, Ignatchenko V, McDonald AC, Garner J, Gramolini AO, Rossant J, Kislinger T. Cell-surface proteomics identifies lineage-specific markers of embryo-derived stem cells. Developmental Cell. 22: 887-901. PMID 22424930 DOI: 10.1016/j.devcel.2012.01.005  0.48
2012 McCann MR, Tamplin OJ, Rossant J, Séguin CA. Tracing notochord-derived cells using a Noto-cre mouse: implications for intervertebral disc development. Disease Models & Mechanisms. 5: 73-82. PMID 22028328 DOI: 10.1242/dmm.008128  0.48
2012 Paca A, Séguin CA, Clements M, Ryczko M, Rossant J, Rodriguez TA, Kunath T. BMP signaling induces visceral endoderm differentiation of XEN cells and parietal endoderm. Developmental Biology. 361: 90-102. PMID 22027433 DOI: 10.1016/j.ydbio.2011.10.013  0.48
2012 Anderson NM, Berberovic Z, Berndl E, Bailey ML, Flenniken AM, Osborne LR, Adamson SL, Rossant J, Wang C, Minden MD, McNagny KM, Paulson RF, Barber DL, Stanford WL. Cytopenia induction by 5-fluorouracil identifies thrombopoietic mutants in sensitized ENU mutagenesis screens. Experimental Hematology. 40: 48-60. PMID 21924221 DOI: 10.1016/j.exphem.2011.09.007  0.48
2011 Tamplin OJ, Cox BJ, Rossant J. Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Developmental Biology. 360: 415-25. PMID 22008794 DOI: 10.1016/j.ydbio.2011.10.002  0.48
2011 Cox B, Sharma P, Evangelou AI, Whiteley K, Ignatchenko V, Ignatchenko A, Baczyk D, Czikk M, Kingdom J, Rossant J, Gramolini AO, Adamson SL, Kislinger T. Translational analysis of mouse and human placental protein and mRNA reveals distinct molecular pathologies in human preeclampsia. Molecular & Cellular Proteomics : McP. 10: M111.012526. PMID 21986993 DOI: 10.1074/mcp.M111.012526  0.48
2011 Rossant J. The impact of developmental biology on pluripotent stem cell research: successes and challenges. Developmental Cell. 21: 20-3. PMID 21763602 DOI: 10.1016/j.devcel.2011.06.010  0.48
2011 Biechele S, Cox BJ, Rossant J. Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos. Developmental Biology. 355: 275-85. PMID 21554866 DOI: 10.1016/j.ydbio.2011.04.029  0.48
2011 Rossant J, Nutter LM, Gertsenstein M. Engineering the embryo. Proceedings of the National Academy of Sciences of the United States of America. 108: 7659-60. PMID 21527721 DOI: 10.1073/pnas.1104844108  0.48
2011 Wright JG, Daneman D, Mainland J, Rossant J. Innovation as the core strategy for the future success of academic health centres. Canadian Journal of Surgery. Journal Canadien De Chirurgie. 54: 150-1. PMID 21443830 DOI: 10.1503/cjs.033810  0.48
2011 Rossant J. Developmental biology: A mouse is not a cow. Nature. 471: 457-8. PMID 21430771 DOI: 10.1038/471457a  0.48
2011 Ochotny N, Flenniken AM, Owen C, Voronov I, Zirngibl RA, Osborne LR, Henderson JE, Adamson SL, Rossant J, Manolson MF, Aubin JE. The V-ATPase a3 subunit mutation R740S is dominant negative and results in osteopetrosis in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 1484-93. PMID 21305608 DOI: 10.1002/jbmr.355  0.48
2011 Ly JP, Onay T, Sison K, Sivaskandarajah G, Sabbisetti V, Li L, Bonventre JV, Flenniken A, Paragas N, Barasch JM, Adamson SL, Osborne L, Rossant J, Schnermann J, Quaggin SE. The Sweet Pee model for Sglt2 mutation. Journal of the American Society of Nephrology : Jasn. 22: 113-23. PMID 21209254 DOI: 10.1681/ASN.2010080888  0.48
2011 Hughes MR, Anderson N, Maltby S, Wong J, Berberovic Z, Birkenmeier CS, Haddon DJ, Garcha K, Flenniken A, Osborne LR, Adamson SL, Rossant J, Peters LL, Minden MD, Paulson RF, et al. A novel ENU-generated truncation mutation lacking the spectrin-binding and C-terminal regulatory domains of Ank1 models severe hemolytic hereditary spherocytosis. Experimental Hematology. 39: 305-20, 320.e1-2. PMID 21193012 DOI: 10.1016/j.exphem.2010.12.009  0.48
2010 Varelas X, Samavarchi-Tehrani P, Narimatsu M, Weiss A, Cockburn K, Larsen BG, Rossant J, Wrana JL. The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway. Developmental Cell. 19: 831-44. PMID 21145499 DOI: 10.1016/j.devcel.2010.11.012  0.48
2010 Lanner F, Rossant J. The role of FGF/Erk signaling in pluripotent cells. Development (Cambridge, England). 137: 3351-60. PMID 20876656 DOI: 10.1242/dev.050146  0.48
2010 Stephenson RO, Yamanaka Y, Rossant J. Disorganized epithelial polarity and excess trophectoderm cell fate in preimplantation embryos lacking E-cadherin. Development (Cambridge, England). 137: 3383-91. PMID 20826529 DOI: 10.1242/dev.050195  0.48
2010 Gertsenstein M, Nutter LM, Reid T, Pereira M, Stanford WL, Rossant J, Nagy A. Efficient generation of germ line transmitting chimeras from C57BL/6N ES cells by aggregation with outbred host embryos. Plos One. 5: e11260. PMID 20582321 DOI: 10.1371/journal.pone.0011260  0.48
2010 Cox BJ, Vollmer M, Tamplin O, Lu M, Biechele S, Gertsenstein M, van Campenhout C, Floss T, Kühn R, Wurst W, Lickert H, Rossant J. Phenotypic annotation of the mouse X chromosome. Genome Research. 20: 1154-64. PMID 20548051 DOI: 10.1101/gr.105106.110  0.48
2010 Zhang K, Li L, Huang C, Shen C, Tan F, Xia C, Liu P, Rossant J, Jing N. Distinct functions of BMP4 during different stages of mouse ES cell neural commitment. Development (Cambridge, England). 137: 2095-105. PMID 20504958 DOI: 10.1242/dev.049494  0.48
2010 Mai S, Wei K, Flenniken A, Adamson SL, Rossant J, Aubin JE, Gong SG. The missense mutation W290R in Fgfr2 causes developmental defects from aberrant IIIb and IIIc signaling. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 1888-900. PMID 20503384 DOI: 10.1002/dvdy.22314  0.48
2010 Ahmed K, Dehghani H, Rugg-Gunn P, Fussner E, Rossant J, Bazett-Jones DP. Global chromatin architecture reflects pluripotency and lineage commitment in the early mouse embryo. Plos One. 5: e10531. PMID 20479880 DOI: 10.1371/journal.pone.0010531  0.48
2010 Rugg-Gunn PJ, Cox BJ, Ralston A, Rossant J. Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo. Proceedings of the National Academy of Sciences of the United States of America. 107: 10783-90. PMID 20479220 DOI: 10.1073/pnas.0914507107  0.48
2010 Cockburn K, Rossant J. Making the blastocyst: lessons from the mouse. The Journal of Clinical Investigation. 120: 995-1003. PMID 20364097 DOI: 10.1172/JCI41229  0.48
2010 Coultas L, Nieuwenhuis E, Anderson GA, Cabezas J, Nagy A, Henkelman RM, Hui CC, Rossant J. Hedgehog regulates distinct vascular patterning events through VEGF-dependent and -independent mechanisms. Blood. 116: 653-60. PMID 20339091 DOI: 10.1182/blood-2009-12-256644  0.48
2010 Andrews PW, Benvenisty N, Knowles BB, McKay RD, Oh SK, Pera MF, Rossant J, Stacey GN. Human ES cell lines--introduction. In Vitro Cellular & Developmental Biology. Animal. 46: 167-8. PMID 20213278 DOI: 10.1007/s11626-010-9306-2  0.48
2010 Akopian V, Andrews PW, Beil S, Benvenisty N, Brehm J, Christie M, Ford A, Fox V, Gokhale PJ, Healy L, Holm F, Hovatta O, Knowles BB, Ludwig TE, ... ... Rossant J, et al. Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells. In Vitro Cellular & Developmental Biology. Animal. 46: 247-58. PMID 20186512 DOI: 10.1007/s11626-010-9297-z  0.48
2010 Yamanaka Y, Lanner F, Rossant J. FGF signal-dependent segregation of primitive endoderm and epiblast in the mouse blastocyst. Development (Cambridge, England). 137: 715-24. PMID 20147376 DOI: 10.1242/dev.043471  0.48
2010 Ralston A, Cox BJ, Nishioka N, Sasaki H, Chea E, Rugg-Gunn P, Guo G, Robson P, Draper JS, Rossant J. Gata3 regulates trophoblast development downstream of Tead4 and in parallel to Cdx2. Development (Cambridge, England). 137: 395-403. PMID 20081188 DOI: 10.1242/dev.038828  0.48
2010 Rossant J. A developmental journey and lessons learned along the way. Molecular Biology of the Cell. 21: 9-10. PMID 20048257 DOI: 10.1091/mbc.E09-08-0657  0.48
2010 Lanner F, Lee KL, Sohl M, Holmborn K, Yang H, Wilbertz J, Poellinger L, Rossant J, Farnebo F. Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state. Stem Cells (Dayton, Ohio). 28: 191-200. PMID 19937756 DOI: 10.1002/stem.265  0.48
2010 Xu K, Nieuwenhuis E, Cohen BL, Wang W, Canty AJ, Danska JS, Coultas L, Rossant J, Wu MY, Piscione TD, Nagy A, Gossler A, Hicks GG, Hui CC, Henkelman RM, et al. Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 298: L45-56. PMID 19897741 DOI: 10.1152/ajplung.90550.2008  0.48
2010 Ralston A, Rossant J. The genetics of induced pluripotency. Reproduction (Cambridge, England). 139: 35-44. PMID 19605512 DOI: 10.1530/REP-09-0024  0.48
2009 Zarzeczny A, Scott C, Hyun I, Bennett J, Chandler J, Chargé S, Heine H, Isasi R, Kato K, Lovell-Badge R, McNagny K, Pei D, Rossant J, Surani A, Taylor PL, et al. iPS cells: mapping the policy issues. Cell. 139: 1032-7. PMID 20005794 DOI: 10.1016/j.cell.2009.11.039  0.48
2009 Rossant J. Reprogramming to pluripotency: from frogs to stem cells. Cell. 138: 1047-50. PMID 19766555 DOI: 10.1016/j.cell.2009.09.003  0.48
2009 Cox B, Kotlyar M, Evangelou AI, Ignatchenko V, Ignatchenko A, Whiteley K, Jurisica I, Adamson SL, Rossant J, Kislinger T. Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology. Molecular Systems Biology. 5: 279. PMID 19536202 DOI: 10.1038/msb.2009.37  0.48
2009 Hotta A, Cheung AY, Farra N, Vijayaragavan K, Séguin CA, Draper JS, Pasceri P, Maksakova IA, Mager DL, Rossant J, Bhatia M, Ellis J. Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency. Nature Methods. 6: 370-6. PMID 19404254 DOI: 10.1038/nmeth.1325  0.48
2009 Rugg-Gunn PJ, Ogbogu U, Rossant J, Caulfield T. The challenge of regulating rapidly changing science: stem cell legislation in Canada. Cell Stem Cell. 4: 285-8. PMID 19341618 DOI: 10.1016/j.stem.2009.03.004  0.48
2009 Nishioka N, Inoue K, Adachi K, Kiyonari H, Ota M, Ralston A, Yabuta N, Hirahara S, Stephenson RO, Ogonuki N, Makita R, Kurihara H, Morin-Kensicki EM, Nojima H, Rossant J, et al. The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass. Developmental Cell. 16: 398-410. PMID 19289085 DOI: 10.1016/j.devcel.2009.02.003  0.48
2009 Ellis J, Bruneau BG, Keller G, Lemischka IR, Nagy A, Rossant J, Srivastava D, Zandstra PW, Stanford WL. Alternative induced pluripotent stem cell characterization criteria for in vitro applications. Cell Stem Cell. 4: 198-9; author reply . PMID 19265656 DOI: 10.1016/j.stem.2009.02.010  0.48
2009 Rossant J, Tam PP. Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse. Development (Cambridge, England). 136: 701-13. PMID 19201946 DOI: 10.1242/dev.017178  0.48
2008 Benedito R, Trindade A, Hirashima M, Henrique D, da Costa LL, Rossant J, Gill PS, Duarte A. Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli. Bmc Developmental Biology. 8: 117. PMID 19087347 DOI: 10.1186/1471-213X-8-117  0.48
2008 Ema M, Mori D, Niwa H, Hasegawa Y, Yamanaka Y, Hitoshi S, Mimura J, Kawabe Y, Hosoya T, Morita M, Shimosato D, Uchida K, Suzuki N, Yanagisawa J, Sogawa K, ... Rossant J, et al. Krüppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs. Cell Stem Cell. 3: 555-67. PMID 18983969 DOI: 10.1016/j.stem.2008.09.003  0.48
2008 Tamplin OJ, Kinzel D, Cox BJ, Bell CE, Rossant J, Lickert H. Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives. Bmc Genomics. 9: 511. PMID 18973680 DOI: 10.1186/1471-2164-9-511  0.48
2008 Walls JR, Coultas L, Rossant J, Henkelman RM. Three-dimensional analysis of vascular development in the mouse embryo. Plos One. 3: e2853. PMID 18682734 DOI: 10.1371/journal.pone.0002853  0.48
2008 Séguin CA, Draper JS, Nagy A, Rossant J. Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells. Cell Stem Cell. 3: 182-95. PMID 18682240 DOI: 10.1016/j.stem.2008.06.018  0.48
2008 Malaval L, Wade-Guéye NM, Boudiffa M, Fei J, Zirngibl R, Chen F, Laroche N, Roux JP, Burt-Pichat B, Duboeuf F, Boivin G, Jurdic P, Lafage-Proust MH, Amédée J, Vico L, ... Rossant J, et al. Bone sialoprotein plays a functional role in bone formation and osteoclastogenesis. The Journal of Experimental Medicine. 205: 1145-53. PMID 18458111 DOI: 10.1084/jem.20071294  0.48
2008 Hirashima M, Sano K, Morisada T, Murakami K, Rossant J, Suda T. Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos. Developmental Biology. 316: 149-59. PMID 18304521 DOI: 10.1016/j.ydbio.2008.01.023  0.48
2008 Rossant J. Stem cells and early lineage development. Cell. 132: 527-31. PMID 18295568 DOI: 10.1016/j.cell.2008.01.039  0.48
2008 Gerbe F, Cox B, Rossant J, Chazaud C. Dynamic expression of Lrp2 pathway members reveals progressive epithelial differentiation of primitive endoderm in mouse blastocyst. Developmental Biology. 313: 594-602. PMID 18083160 DOI: 10.1016/j.ydbio.2007.10.048  0.48
2008 Ralston A, Rossant J. Cdx2 acts downstream of cell polarization to cell-autonomously promote trophectoderm fate in the early mouse embryo. Developmental Biology. 313: 614-29. PMID 18067887 DOI: 10.1016/j.ydbio.2007.10.054  0.48
2007 Yamanaka Y, Tamplin OJ, Beckers A, Gossler A, Rossant J. Live imaging and genetic analysis of mouse notochord formation reveals regional morphogenetic mechanisms. Developmental Cell. 13: 884-96. PMID 18061569 DOI: 10.1016/j.devcel.2007.10.016  0.48
2007 Shawber CJ, Funahashi Y, Francisco E, Vorontchikhina M, Kitamura Y, Stowell SA, Borisenko V, Feirt N, Podgrabinska S, Shiraishi K, Chawengsaksophak K, Rossant J, Accili D, Skobe M, Kitajewski J. Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression. The Journal of Clinical Investigation. 117: 3369-82. PMID 17948123 DOI: 10.1172/JCI24311  0.48
2007 Rossant J, Hogan B. Retrospective. Anne McLaren (1927-2007). Science (New York, N.Y.). 317: 609. PMID 17673646 DOI: 10.1126/science.1147801  0.48
2007 Rossant J. Stem cells: the magic brew. Nature. 448: 260-2. PMID 17637646 DOI: 10.1038/448260a  0.48
2007 Adewumi O, Aflatoonian B, Ahrlund-Richter L, Amit M, Andrews PW, Beighton G, Bello PA, Benvenisty N, Berry LS, Bevan S, Blum B, Brooking J, Chen KG, Choo AB, ... ... Rossant J, et al. Characterization of human embryonic stem cell lines by the International Stem Cell Initiative. Nature Biotechnology. 25: 803-16. PMID 17572666 DOI: 10.1038/nbt1318  0.48
2007 Karpowicz P, Inoue T, Runciman S, Deveale B, Seaberg R, Gertsenstein M, Byers L, Yamanaka Y, Tondat S, Slevin J, Hitoshi S, Rossant J, van der Kooy D. Adhesion is prerequisite, but alone insufficient, to elicit stem cell pluripotency. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5437-47. PMID 17507566 DOI: 10.1523/JNEUROSCI.0300-07.2007  0.48
2007 Cox B, Kislinger T, Wigle DA, Kannan A, Brown K, Okubo T, Hogan B, Jurisica I, Frey B, Rossant J, Emili A. Integrated proteomic and transcriptomic profiling of mouse lung development and Nmyc target genes. Molecular Systems Biology. 3: 109. PMID 17486137 DOI: 10.1038/msb4100151  0.48
2007 Collins FS, Finnell RH, Rossant J, Wurst W. A new partner for the international knockout mouse consortium. Cell. 129: 235. PMID 17448981 DOI: 10.1016/j.cell.2007.04.007  0.48
2007 Georgiades P, Cox B, Gertsenstein M, Chawengsaksophak K, Rossant J. Trophoblast-specific gene manipulation using lentivirus-based vectors. Biotechniques. 42: 317-8, 320, 322-5. PMID 17390538 DOI: 10.2144/000112341  0.48
2007 Kimura-Yoshida C, Tian E, Nakano H, Amazaki S, Shimokawa K, Rossant J, Aizawa S, Matsuo I. Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes. Proceedings of the National Academy of Sciences of the United States of America. 104: 5919-24. PMID 17389379 DOI: 10.1073/pnas.0607779104  0.48
2007 Rossant J. Stem cells and lineage development in the mammalian blastocyst. Reproduction, Fertility, and Development. 19: 111-8. PMID 17389140 DOI: 10.1071/RD06125  0.48
2007 Xie G, Clapcote SJ, Nieman BJ, Tallerico T, Huang Y, Vukobradovic I, Cordes SP, Osborne LR, Rossant J, Sled JG, Henderson JT, Roder JC. Forward genetic screen of mouse reveals dominant missense mutation in the P/Q-type voltage-dependent calcium channel, CACNA1A. Genes, Brain, and Behavior. 6: 717-27. PMID 17376154 DOI: 10.1111/j.1601-183X.2007.00302.x  0.48
2007 Daley GQ, Ahrlund Richter L, Auerbach JM, Benvenisty N, Charo RA, Chen G, Deng HK, Goldstein LS, Hudson KL, Hyun I, Junn SC, Love J, Lee EH, McLaren A, Mummery CL, ... ... Rossant J, et al. Ethics. The ISSCR guidelines for human embryonic stem cell research. Science (New York, N.Y.). 315: 603-4. PMID 17272706 DOI: 10.1126/science.1139337  0.48
2007 Hellström M, Phng LK, Hofmann JJ, Wallgard E, Coultas L, Lindblom P, Alva J, Nilsson AK, Karlsson L, Gaiano N, Yoon K, Rossant J, Iruela-Arispe ML, Kalén M, Gerhardt H, et al. Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis. Nature. 445: 776-80. PMID 17259973 DOI: 10.1038/nature05571  0.48
2007 Takeuchi JK, Lickert H, Bisgrove BW, Sun X, Yamamoto M, Chawengsaksophak K, Hamada H, Yost HJ, Rossant J, Bruneau BG. Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry. Proceedings of the National Academy of Sciences of the United States of America. 104: 846-51. PMID 17210915 DOI: 10.1073/pnas.0608118104  0.48
2006 Stanford WL, Epp T, Reid T, Rossant J. Gene Trapping in Embryonic Stem Cells Methods in Enzymology. 420: 136-162. PMID 17161697 DOI: 10.1016/S0076-6879(06)20008-9  0.48
2006 Zhang W, Walker E, Tamplin OJ, Rossant J, Stanford WL, Hughes TR. Zfp206 regulates ES cell gene expression and differentiation Nucleic Acids Research. 34: 4780-4790. PMID 16971461 DOI: 10.1093/nar/gkl631  0.48
2006 Chazaud C, Rossant J. Disruption of early proximodistal patterning and AVE formation in Apc mutants Development. 133: 3379-3387. PMID 16887818 DOI: 10.1242/dev.02523  0.48
2006 Wada T, Haigh JJ, Ema M, Hitoshi S, Chaddah R, Rossant J, Nagy A, van der Kooy D. Vascular endothelial growth factor directly inhibits primitive neural stem cell survival but promotes definitive neural stem cell survival. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6803-12. PMID 16793887 DOI: 10.1523/JNEUROSCI.0526-06.2006  0.48
2006 Yamanaka Y, Ralston A, Stephenson RO, Rossant J. Cell and molecular regulation of the mouse blastocyst. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 235: 2301-14. PMID 16773657 DOI: 10.1002/dvdy.20844  0.48
2006 Chazaud C, Yamanaka Y, Pawson T, Rossant J. Early lineage segregation between epiblast and primitive endoderm in mouse blastocysts through the Grb2-MAPK pathway. Developmental Cell. 10: 615-24. PMID 16678776 DOI: 10.1016/j.devcel.2006.02.020  0.48
2006 Spradling A, Ganetsky B, Hieter P, Johnston M, Olson M, Orr-Weaver T, Rossant J, Sanchez A, Waterston R. New roles for model genetic organisms in understanding and treating human disease: report from the 2006 Genetics Society of America meeting. Genetics. 172: 2025-32. PMID 16636111  0.48
2006 Kislinger T, Cox B, Kannan A, Chung C, Hu P, Ignatchenko A, Scott MS, Gramolini AO, Morris Q, Hallett MT, Rossant J, Hughes TR, Frey B, Emili A. Global survey of organ and organelle protein expression in mouse: combined proteomic and transcriptomic profiling. Cell. 125: 173-86. PMID 16615898 DOI: 10.1016/j.cell.2006.01.044  0.48
2006 Takaoka K, Yamamoto M, Shiratori H, Meno C, Rossant J, Saijoh Y, Hamada H. The mouse embryo autonomously acquires anterior-posterior polarity at implantation. Developmental Cell. 10: 451-9. PMID 16580991 DOI: 10.1016/j.devcel.2006.02.017  0.48
2006 Bowles J, Knight D, Smith C, Wilhelm D, Richman J, Mamiya S, Yashiro K, Chawengsaksophak K, Wilson MJ, Rossant J, Hamada H, Koopman P. Retinoid signaling determines germ cell fate in mice. Science (New York, N.Y.). 312: 596-600. PMID 16574820 DOI: 10.1126/science.1125691  0.48
2006 Ralston A, Rossant J. How signaling promotes stem cell survival: Trophoblast stem cells and shp2 Developmental Cell. 10: 275-276. PMID 16516829 DOI: 10.1016/j.devcel.2006.02.007  0.48
2006 Slevin JC, Byers L, Gertsenstein M, Qu D, Mu J, Sunn N, Kingdom JCP, Rossant J, Adamson SL. High resolution ultrasound-guided microinjection for interventional studies of early embryonic and placental development in vivo in mice Bmc Developmental Biology. 6. PMID 16504164 DOI: 10.1186/1471-213X-6-10  0.48
2006 Georgiades P, Rossant J. Ets2 is necessary in trophoblast for normal embryonic anteroposterior axis development Development. 133: 1059-1068. PMID 16481355 DOI: 10.1242/dev.02277  0.48
2006 Zhao H, Yang Y, Partanen J, Ciruna BG, Rossant J, Robinson ML. Fibroblast growth factor receptor 1 (Fgfr1) is not essential for lens fiber differentiation in mice. Molecular Vision. 12: 15-25. PMID 16446698  0.48
2006 Eremina V, Cui S, Gerber H, Ferrara N, Haigh J, Nagy A, Ema M, Rossant J, Jothy S, Miner JH, Quaggin SE. Vascular endothelial growth factor a signaling in the podocyte-endothelial compartment is required for mesangial cell migration and survival. Journal of the American Society of Nephrology : Jasn. 17: 724-35. PMID 16436493 DOI: 10.1681/ASN.2005080810  0.48
2006 Nord AS, Chang PJ, Conklin BR, Cox AV, Harper CA, Hicks GG, Huang CC, Johns SJ, Kawamoto M, Liu S, Meng EC, Morris JH, Rossant J, Ruiz P, Skarnes WC, et al. The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse. Nucleic Acids Research. 34: D642-8. PMID 16381950 DOI: 10.1093/nar/gkj097  0.48
2006 Quinn J, Kunath T, Rossant J. Mouse trophoblast stem cells Methods in Molecular Medicine. 121: 125-148. PMID 16251740  0.48
2006 Ema M, Takahashi S, Rossant J. Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors Blood. 107: 111-117. PMID 16166582 DOI: 10.1182/blood-2005-05-1970  0.48
2005 Coultas L, Chawengsaksophak K, Rossant J. Endothelial cells and VEGF in vascular development Nature. 438: 937-945. PMID 16355211 DOI: 10.1038/nature04479  0.48
2005 Niwa H, Toyooka Y, Shimosato D, Strumpf D, Takahashi K, Yagi R, Rossant J. Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiation Cell. 123: 917-929. PMID 16325584 DOI: 10.1016/j.cell.2005.08.040  0.48
2005 Nieman BJ, Bock NA, Bishop J, Chen XJ, Sled JG, Rossant J, Henkelman RM. Magnetic resonance imaging for detection and analysis of mouse phenotypes. Nmr in Biomedicine. 18: 447-68. PMID 16206127 DOI: 10.1002/nbm.981  0.48
2005 Flenniken AM, Osborne LR, Anderson N, Ciliberti N, Fleming C, Gittens JE, Gong XQ, Kelsey LB, Lounsbury C, Moreno L, Nieman BJ, Peterson K, Qu D, Roscoe W, Shao Q, ... ... Rossant J, et al. A Gja1 missense mutation in a mouse model of oculodentodigital dysplasia. Development (Cambridge, England). 132: 4375-86. PMID 16155213 DOI: 10.1242/dev.02011  0.48
2005 Frey BJ, Mohammad N, Morris QD, Zhang W, Robinson MD, Mnaimneh S, Chang R, Pan Q, Sat E, Rossant J, Bruneau BG, Aubin JE, Blencowe BJ, Hughes TR. Genome-wide analysis of mouse transcripts using exon microarrays and factor graphs. Nature Genetics. 37: 991-6. PMID 16127451 DOI: 10.1038/ng1630  0.48
2005 Andrews PW, Benvenisty N, McKay R, Pera MF, Rossant J, Semb H, Stacey GN. The International Stem Cell Initiative: toward benchmarks for human embryonic stem cell research. Nature Biotechnology. 23: 795-7. PMID 16003358 DOI: 10.1038/nbt0705-795  0.48
2005 Ralston A, Rossant J. Genetic regulation of stem cell origins in the mouse embryo Clinical Genetics. 68: 106-112. PMID 15996204 DOI: 10.1111/j.1399-0004.2005.00478.x  0.48
2005 Lickert H, Cox B, Wehrle C, Taketo MM, Kemler R, Rossant J. Dissecting Wnt/β-catenin signaling during gastrulation using RNA interference in mouse embryos Development. 132: 2599-2609. PMID 15857914 DOI: 10.1242/dev.01842  0.48
2005 Wood GA, Flenniken A, Osborne L, Fleming C, Vukobradovic I, Morikawa L, Xu Q, Porter R, Adamson SL, Rossant J, McKerlie C. Two mouse mutations mapped to chromosome 11 with differing morphologies but similar progressive inflammatory alopecia Experimental Dermatology. 14: 373-379. PMID 15854131 DOI: 10.1111/j.0906-6705.2005.00291.x  0.48
2005 Strumpf D, Mao CA, Yamanaka Y, Ralston A, Chawengsaksophak K, Beck F, Rossant J. Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst. Development (Cambridge, England). 132: 2093-102. PMID 15788452 DOI: 10.1242/dev.01801  0.48
2005 Kunath T, Arnaud D, Uy GD, Okamoto I, Chureau C, Yamanaka Y, Heard E, Gardner RL, Avner P, Rossant J. Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocysts. Development (Cambridge, England). 132: 1649-61. PMID 15753215 DOI: 10.1242/dev.01715  0.48
2004 Clark AT, Goldowitz D, Takahashi JS, Vitaterna MH, Siepka SM, Peters LL, Frankel WN, Carlson GA, Rossant J, Nadeau JH, Justice MJ. Implementing large-scale ENU mutagenesis screens in North America. Genetica. 122: 51-64. PMID 15619961 DOI: 10.1007/s10709-004-1436-6  0.48
2004 Zhang W, Morris QD, Chang R, Shai O, Bakowski MA, Mitsakakis N, Mohammad N, Robinson MD, Zirngibl R, Somogyi E, Laurin N, Eftekharpour E, Sat E, Grigull J, Pan Q, ... ... Rossant J, et al. The functional landscape of mouse gene expression. Journal of Biology. 3: 21. PMID 15588312 DOI: 10.1186/jbiol16  0.48
2004 Lickert H, Takeuchi JK, Von Both I, Walls JR, McAuliffe F, Adamson SL, Henkelman RM, Wrana JL, Rossant J, Bruneau BG. Baf60c is essential for function of BAF chromatin remodelling complexes in heart development. Nature. 432: 107-12. PMID 15525990 DOI: 10.1038/nature03071  0.48
2004 Duarte A, Hirashima M, Benedito R, Trindade A, Diniz P, Bekman E, Costa L, Henrique D, Rossant J. Dosage-sensitive requirement for mouse Dll4 in artery development. Genes & Development. 18: 2474-8. PMID 15466159 DOI: 10.1101/gad.1239004  0.48
2004 von Both I, Silvestri C, Erdemir T, Lickert H, Walls JR, Henkelman RM, Rossant J, Harvey RP, Attisano L, Wrana JL. Foxh1 is essential for development of the anterior heart field. Developmental Cell. 7: 331-45. PMID 15363409 DOI: 10.1016/j.devcel.2004.07.023  0.48
2004 Kibschull M, Nassiry M, Dunk C, Gellhaus A, Quinn JA, Rossant J, Lye SJ, Winterhager E. Connexin31-deficient trophoblast stem cells: a model to analyze the role of gap junction communication in mouse placental development. Developmental Biology. 273: 63-75. PMID 15302598 DOI: 10.1016/j.ydbio.2004.04.037  0.48
2004 Rossant J, Tam PPL. Emerging asymmetry and embryonic patterning in early mouse development Developmental Cell. 7: 155-164. PMID 15296713 DOI: 10.1016/j.devcel.2004.07.012  0.48
2004 Rossant J. Lineage development and polar asymmetries in the peri-implantation mouse blastocyst Seminars in Cell and Developmental Biology. 15: 573-581. PMID 15271303 DOI: 10.1016/j.semcdb.2004.04.003  0.48
2004 Abdelkhalek HB, Beckers A, Schuster-Gossler K, Pavlova MN, Burkhardt H, Lickert H, Rossant J, Reinhardt R, Schalkwyk LC, Müller I, Herrmann BG, Ceolin M, Rivera-Pomar R, Gossler A. The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation. Genes & Development. 18: 1725-36. PMID 15231714 DOI: 10.1101/gad.303504  0.48
2004 Nishimura T, Dunk C, Lu Y, Feng X, Gellhaus A, Winterhager E, Rossant J, Lye SJ. Gap junctions are required for trophoblast proliferation in early human placental development Placenta. 25: 595-607. PMID 15193866 DOI: 10.1016/j.placenta.2004.01.002  0.48
2004 Skarnes WC, von Melchner H, Wurst W, Hicks G, Nord AS, Cox T, Young SG, Ruiz P, Soriano P, Tessier-Lavigne M, Conklin BR, Stanford WL, Rossant J. A public gene trap resource for mouse functional genomics. Nature Genetics. 36: 543-4. PMID 15167922 DOI: 10.1038/ng0604-543  0.48
2004 Chawengsaksophak K, De Graaff W, Rossant J, Deschamps J, Beck F. Cdx2 is essential for axial elongation in mouse development Proceedings of the National Academy of Sciences of the United States of America. 101: 7641-7645. PMID 15136723 DOI: 10.1073/pnas.0401654101  0.48
2004 Myers AP, Corson LB, Rossant J, Baker JC. Characterization of mouse Rsk4 as an inhibitor of fibroblast growth factor-RAS-extracellular signal-regulated kinase signaling. Molecular and Cellular Biology. 24: 4255-66. PMID 15121846 DOI: 10.1128/MCB.24.10.4255-4266.2004  0.48
2004 Hirashima M, Bernstein A, Stanford WL, Rossant J. Gene-trap expression screening to identify endothelial-specific genes. Blood. 104: 711-8. PMID 15090446 DOI: 10.1182/blood-2004-01-0254  0.48
2004 Kunath T, Strumpf D, Rossant J. Early trophoblast determination and stem cell maintenance in the mouse - A review Placenta. 25: S32-S38. PMID 15033304 DOI: 10.1016/j.placenta.2004.01.015  0.48
2004 To C, Epp T, Reid T, Lan Q, Yu M, Li CY, Ohishi M, Hant P, Tsao N, Casallo G, Rossant J, Osborne LR, Stanford WL. The Centre for Modeling Human Disease gene trap resource Nucleic Acids Research. 32: D557-D559. PMID 14681480  0.48
2004 Haigh JJ, Ema M, Haigh K, Gertsenstein M, Greer P, Rossant J, Nagy A, Wagner EF. Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells Blood. 103: 912-920. PMID 14525765 DOI: 10.1182/blood-2003-07-2343  0.48
2004 Kunath T, Rossant J. Isolation and Maintenance of Trophoblast Stem Cells Handbook of Stem Cells. 1: 479-481. DOI: 10.1016/B978-012436643-5/50054-7  0.48
2003 Sharov AA, Piao Y, Matoba R, Dudekula DB, Qian Y, VanBuren V, Falco G, Martin PR, Stagg CA, Bassey UC, Wang Y, Carter MG, Hamatani T, Aiba K, Akutsu H, ... ... Rossant J, et al. Transcriptome analysis of mouse stem cells and early embryos. Plos Biology. 1: E74. PMID 14691545 DOI: 10.1371/journal.pbio.0000074  0.48
2003 Dunk C, Petkovic L, Baczyk D, Rossant J, Winterhager E, Lye SJ. A Novel in Vitro Model of Trophoblast-Mediated Decidual Blood Vessel Remodeling Laboratory Investigation. 83: 1821-1828. PMID 14691300 DOI: 10.1097/01.LAB.0000101730.69754.5A  0.48
2003 Hirashima M, Lu Y, Byers L, Rossant J. Trophoblast expression of fms-like tyrosine kinase 1 is not required for the establishment of the maternal-fetal interface in the mouse placenta Proceedings of the National Academy of Sciences of the United States of America. 100: 15637-15642. PMID 14668430 DOI: 10.1073/pnas.2635424100  0.48
2003 Tam PPL, Rossant J. Mouse embryonic chimeras: Tools for studying mammalian development Development. 130: 6155-6163. PMID 14623817 DOI: 10.1242/dev.00893  0.48
2003 Pearce EL, Mullen AC, Martins GA, Krawczyk CM, Hutchins AS, Zediak VP, Banica M, DiCioccio CB, Gross DA, Mao CA, Shen H, Cereb N, Yang SY, Lindsten T, Rossant J, et al. Control of effector CD8+ T cell function by the transcription factor Eomesodermin. Science (New York, N.Y.). 302: 1041-3. PMID 14605368 DOI: 10.1126/science.1090148  0.48
2003 Rossant J, Chazaud C, Yamanaka Y. Lineage allocation and asymmetries in the early mouse embryo. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 358: 1341-8; discussion 1. PMID 14511480 DOI: 10.1098/rstb.2003.1329  0.48
2003 Gardner RL, Davies TJ. The basis and significance of pre-patterning in mammals. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 358: 1331-8; discussion 1. PMID 14511479 DOI: 10.1098/rstb.2003.1322  0.48
2003 Rossant J. A balancing act Nature. 425: 29+31-32. PMID 12955124  0.48
2003 Corson LB, Yamanaka Y, Lai KM, Rossant J. Spatial and temporal patterns of ERK signaling during mouse embryogenesis. Development (Cambridge, England). 130: 4527-37. PMID 12925581 DOI: 10.1242/dev.00669  0.48
2003 Ema M, Rossant J. Cell Fate Decisions in Early Blood Vessel Formation Trends in Cardiovascular Medicine. 13: 254-259. PMID 12922023 DOI: 10.1016/S1050-1738(03)00105-1  0.48
2003 Rossant J, Hirashima M. Vascular development and patterning: Making the right choices Current Opinion in Genetics and Development. 13: 408-412. PMID 12888015 DOI: 10.1016/S0959-437X(03)00080-7  0.48
2003 Chazaud C, Dollé P, Rossant J, Mollard R. Retinoic acid signaling regulates murine bronchial tubule formation. Mechanisms of Development. 120: 691-700. PMID 12834868 DOI: 10.1016/S0925-4773(03)00048-0  0.48
2003 Bachiller D, Klingensmith J, Shneyder N, Tran U, Anderson R, Rossant J, De Robertis EM. The role of chordin/Bmp signals in mammalian pharyngeal development and DiGeorge syndrome. Development (Cambridge, England). 130: 3567-78. PMID 12810603 DOI: 10.1242/dev.00581  0.48
2003 Rossant J. Targeting mammalian genes - Rats join in and mice move ahead Nature Biotechnology. 21: 625-627. PMID 12776146 DOI: 10.1038/nbt0603-625  0.48
2003 Brivanlou AH, Gage FH, Jaenisch R, Jessell T, Melton D, Rossant J. Stem cells. Setting standards for human embryonic stem cells. Science (New York, N.Y.). 300: 913-6. PMID 12738841 DOI: 10.1126/science.1082940  0.48
2003 Rossant J, Scherer SW. The mouse genome sequence - The end of the tail, or just the beginning? Genome Biology. 4. PMID 12702199 DOI: 10.1186/gb-2003-4-4-109  0.48
2003 Trokovic R, Trokovic N, Hernesniemi S, Pirvola U, Vogt Weisenhorn DM, Rossant J, McMahon AP, Wurst W, Partanen J. FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals. The Embo Journal. 22: 1811-23. PMID 12682014 DOI: 10.1093/emboj/cdg169  0.48
2003 Kunath T, Gish G, Lickert H, Jones N, Pawson T, Rossant J. Transgenic RNA interference in ES cell-derived embryos recapitulates a genetic null phenotype Nature Biotechnology. 21: 559-561. PMID 12679785 DOI: 10.1038/nbt813  0.48
2003 Kislinger T, Rahman K, Radulovic D, Cox B, Rossant J, Emili A. PRISM, a generic large scale proteomic investigation strategy for mammals Molecular & Cellular Proteomics : McP. 2: 96-106. PMID 12644571  0.48
2003 Motoike T, Markham DW, Rossant J, Sato TN. Evidence for novel fate of Flk1+ progenitor: contribution to muscle lineage. Genesis (New York, N.Y. : 2000). 35: 153-9. PMID 12640619 DOI: 10.1002/gene.10175  0.48
2003 Hébert JM, Lin M, Partanen J, Rossant J, McConnell SK. FGF signaling through FGFR1 is required for olfactory bulb morphogenesis. Development (Cambridge, England). 130: 1101-11. PMID 12571102 DOI: 10.1242/dev.00334  0.48
2003 Ema M, Faloon P, Zhang WJ, Hirashima M, Reid T, Stanford WL, Orkin S, Choi K, Rossant J. Combinatorial effects of Flk1 and Tal1 on vascular and hematopoietic development in the mouse Genes and Development. 17: 380-393. PMID 12569129 DOI: 10.1101/gad.1049803  0.48
2002 Tanaka TS, Kunath T, Kimber WL, Jaradat SA, Stagg CA, Usuda M, Yokota T, Niwa H, Rossant J, Ko MS. Gene expression profiling of embryo-derived stem cells reveals candidate genes associated with pluripotency and lineage specificity. Genome Research. 12: 1921-8. PMID 12466296 DOI: 10.1101/gr.670002  0.48
2002 Rossant J, Howard L. Signaling pathways in vascular development Annual Review of Cell and Developmental Biology. 18: 541-573. PMID 12142271 DOI: 10.1146/annurev.cellbio.18.012502.105825  0.48
2002 Wigle DA, Jurisica I, Radulovich N, Pintilie M, Rossant J, Liu N, Lu C, Woodgett J, Seiden I, Johnston M, Keshavjee S, Darling G, Winton T, Breitkreutz BJ, Jorgenson P, et al. Molecular profiling of non-small cell lung cancer and correlation with disease-free survival. Cancer Research. 62: 3005-8. PMID 12036904  0.48
2002 Bayle JH, Randazzo F, Johnen G, Kaufman S, Nagy A, Rossant J, Crabtree GR. Hyperphenylalaninemia and impaired glucose tolerance in mice lacking the bifunctional DCoH gene. The Journal of Biological Chemistry. 277: 28884-91. PMID 12011081 DOI: 10.1074/jbc.M201983200  0.48
2002 Rossant J. Nuclear transplantation: A monoclonal mouse? Nature. 415: 967-969. PMID 11875546 DOI: 10.1038/415967a  0.48
2000 Saxton TM, Ciruna BG, Holmyard D, Kulkarni S, Harpal K, Rossant J, Pawson T. The SH2 tyrosine phosphatase shp2 is required for mammalian limb development. Nature Genetics. 24: 420-3. PMID 10742110 DOI: 10.1038/74279  0.48
1999 Ciruna BG, Rossant J. Expression of the T-box gene Eomesodermin during early mouse development. Mechanisms of Development. 81: 199-203. PMID 10330500 DOI: 10.1016/S0925-4773(98)00243-3  1
1999 Barrantes IB, Elia AJ, Wünsch K, Hrabe de Angelis MH, Mak TW, Rossant J, Conlon RA, Gossler A, de la Pompa JL. Interaction between Notch signalling and Lunatic fringe during somite boundary formation in the mouse. Current Biology : Cb. 9: 470-80. PMID 10330372 DOI: 10.1016/S0960-9822(99)80212-7  0.48
1999 Tropepe V, Sibilia M, Ciruna BG, Rossant J, Wagner EF, van der Kooy D. Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon. Developmental Biology. 208: 166-88. PMID 10075850 DOI: 10.1006/dbio.1998.9192  0.48
1997 Ciruna BG, Schwartz L, Harpal K, Yamaguchi TP, Rossant J. Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: a role for FGFR1 in morphogenetic movement through the primitive streak. Development (Cambridge, England). 124: 2829-41. PMID 9226454  1
1997 de la Pompa JL, Wakeham A, Correia KM, Samper E, Brown S, Aguilera RJ, Nakano T, Honjo T, Mak TW, Rossant J, Conlon RA. Conservation of the Notch signalling pathway in mammalian neurogenesis. Development (Cambridge, England). 124: 1139-48. PMID 9102301  0.48
1995 Luo J, Pasceri P, Conlon RA, Rossant J, Giguère V. Mice lacking all isoforms of retinoic acid receptor beta develop normally and are susceptible to the teratogenic effects of retinoic acid. Mechanisms of Development. 53: 61-71. PMID 8555112 DOI: 10.1016/0925-4773(95)00424-6  0.48
1995 Conlon RA, Reaume AG, Rossant J. Notch1 is required for the coordinate segmentation of somites. Development (Cambridge, England). 121: 1533-45. PMID 7789282  0.48
1995 Brown A, Bernier G, Mathieu M, Rossant J, Kothary R. The mouse dystonia musculorum gene is a neural isoform of bullous pemphigoid antigen 1. Nature Genetics. 10: 301-6. PMID 7670468 DOI: 10.1038/ng0795-301  0.48
1994 Brown A, Copeland NG, Gilbert DJ, Jenkins NA, Rossant J, Kothary R. The genomic structure of an insertional mutation in the dystonia musculorum locus. Genomics. 20: 371-6. PMID 8034309 DOI: 10.1006/geno.1994.1190  0.48
1994 Brown A, Lemieux N, Rossant J, Kothary R. Human homolog of a mouse sequence from the dystonia musculorum locus is on chromosome 6p12. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 5: 434-7. PMID 7919656 DOI: 10.1007/BF00357004  0.48
1994 Ang SL, Conlon RA, Jin O, Rossant J. Positive and negative signals from mesoderm regulate the expression of mouse Otx2 in ectoderm explants. Development (Cambridge, England). 120: 2979-89. PMID 7607086  0.48
1993 Moens CB, Stanton BR, Parada LF, Rossant J. Defects in heart and lung development in compound heterozygotes for two different targeted mutations at the N-myc locus. Development (Cambridge, England). 119: 485-99. PMID 8287798  0.48
1993 Yamaguchi TP, Dumont DJ, Conlon RA, Breitman ML, Rossant J. flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors. Development (Cambridge, England). 118: 489-98. PMID 8223275  0.48
1992 Dumont DJ, Yamaguchi TP, Conlon RA, Rossant J, Breitman ML. tek, a novel tyrosine kinase gene located on mouse chromosome 4, is expressed in endothelial cells and their presumptive precursors. Oncogene. 7: 1471-80. PMID 1630810  0.48
1992 Moens CB, Auerbach AB, Conlon RA, Joyner AL, Rossant J. A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung. Genes & Development. 6: 691-704. PMID 1577267  0.48
1992 Reaume AG, Conlon RA, Zirngibl R, Yamaguchi TP, Rossant J. Expression analysis of a Notch homologue in the mouse embryo. Developmental Biology. 154: 377-87. PMID 1426644 DOI: 10.1016/0012-1606(92)90076-S  0.48
1992 Conlon RA, Rossant J. Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo. Development (Cambridge, England). 116: 357-68. PMID 1363087  0.48
1992 Yamaguchi TP, Conlon RA, Rossant J. Expression of the fibroblast growth factor receptor FGFR-1/flg during gastrulation and segmentation in the mouse embryo. Developmental Biology. 152: 75-88. PMID 1321062 DOI: 10.1016/0012-1606(92)90157-C  0.48
1989 Kothary R, Clapoff S, Darling S, Perry MD, Moran LA, Rossant J. Inducible expression of an hsp68-lacZ hybrid gene in transgenic mice. Development (Cambridge, England). 105: 707-14. PMID 2557196  0.48
1988 Varmuza S, Prideaux V, Kothary R, Rossant J. Polytene chromosomes in mouse trophoblast giant cells. Development (Cambridge, England). 102: 127-34. PMID 3166422  0.48
1988 Kothary R, Clapoff S, Brown A, Campbell R, Peterson A, Rossant J. A transgene containing lacZ inserted into the dystonia locus is expressed in neural tube. Nature. 335: 435-7. PMID 3138544 DOI: 10.1038/335435a0  0.48
1987 Kothary R, Perry MD, Moran LA, Rossant J. Cell-lineage-specific expression of the mouse hsp68 gene during embryogenesis. Developmental Biology. 121: 342-8. PMID 3582732 DOI: 10.1016/0012-1606(87)90170-9  0.48
1985 Huszar D, Balling R, Kothary R, Magli MC, Hozumi N, Rossant J, Bernstein A. Insertion of a bacterial gene into the mouse germ line using an infectious retrovirus vector. Proceedings of the National Academy of Sciences of the United States of America. 82: 8587-91. PMID 2417225  0.48
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