Caroline Dean - Publications

Affiliations: 
Cell and Developmental Biology John Innes Centre, UK 

162 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Nielsen M, Menon G, Zhao Y, Mateo-Bonmati E, Wolff P, Zhou S, Howard M, Dean C. and PRC2 function in parallel to silence during vernalization. Proceedings of the National Academy of Sciences of the United States of America. 121: e2311474121. PMID 38236739 DOI: 10.1073/pnas.2311474121  0.368
2023 Franco-Echevarría E, Nielsen M, Schulten A, Cheema J, Morgan TE, Bienz M, Dean C. Distinct accessory roles of VEL proteins in Polycomb silencing. Genes & Development. PMID 37734835 DOI: 10.1101/gad.350814.123  0.38
2022 Fiedler M, Franco-Echevarría E, Schulten A, Nielsen M, Rutherford TJ, Yeates A, Ahsan B, Dean C, Bienz M. Head-to-tail polymerization by VEL proteins underpins cold-induced Polycomb silencing in flowering control. Cell Reports. 41: 111607. PMID 36351412 DOI: 10.1016/j.celrep.2022.111607  0.315
2022 Mikulski P, Wolff P, Lu T, Nielsen M, Echevarria EF, Zhu D, Questa JI, Saalbach G, Martins C, Dean C. VAL1 acts as an assembly platform co-ordinating co-transcriptional repression and chromatin regulation at Arabidopsis FLC. Nature Communications. 13: 5542. PMID 36130923 DOI: 10.1038/s41467-022-32897-7  0.406
2021 Xu C, Fang X, Lu T, Dean C. Antagonistic cotranscriptional regulation through ARGONAUTE1 and the THO/TREX complex orchestrates transcriptional output. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34789567 DOI: 10.1073/pnas.2113757118  0.667
2021 Zhu P, Lister C, Dean C. Cold-induced Arabidopsis FRIGIDA nuclear condensates for FLC repression. Nature. 599: 657-661. PMID 34732891 DOI: 10.1038/s41586-021-04062-5  0.388
2021 Baxter CL, Šviković S, Sale JE, Dean C, Costa S. The intersection of DNA replication with antisense 3' RNA processing in chromatin silencing. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34260408 DOI: 10.1073/pnas.2107483118  0.325
2021 Zhao Y, Zhu P, Hepworth J, Bloomer R, Antoniou-Kourounioti RL, Doughty J, Heckmann A, Xu C, Yang H, Dean C. Natural temperature fluctuations promote regulation of . Genes & Development. 35: 888-898. PMID 33985972 DOI: 10.1101/gad.348362.121  0.711
2021 Xu C, Wu Z, Duan HC, Fang X, Jia G, Dean C. R-loop resolution promotes co-transcriptional chromatin silencing. Nature Communications. 12: 1790. PMID 33741984 DOI: 10.1038/s41467-021-22083-6  0.651
2021 Menon G, Schulten A, Dean C, Howard M. Digital paradigm for Polycomb epigenetic switching and memory. Current Opinion in Plant Biology. 61: 102012. PMID 33662809 DOI: 10.1016/j.pbi.2021.102012  0.364
2020 Hepworth J, Antoniou-Kourounioti RL, Berggren K, Selga C, Tudor EH, Yates B, Cox D, Collier Harris BR, Irwin JA, Howard M, Säll T, Holm S, Dean C. Natural variation in autumn expression is the major adaptive determinant distinguishing Arabidopsis haplotypes. Elife. 9. PMID 32902380 DOI: 10.7554/Elife.57671  0.385
2020 Zhao Y, Antoniou-Kourounioti RL, Calder G, Dean C, Howard M. Temperature-dependent growth contributes to long-term cold sensing. Nature. PMID 32669706 DOI: 10.1038/S41586-020-2485-4  0.378
2020 Bloomer RH, Hutchison CE, Bäurle I, Walker J, Fang X, Perera P, Velanis CN, Gümüs S, Spanos C, Rappsilber J, Feng X, Goodrich J, Dean C. The epigenetic regulator ICU11 as an accessory protein of Polycomb Repressive Complex 2. Proceedings of the National Academy of Sciences of the United States of America. PMID 32601198 DOI: 10.1073/Pnas.1920621117  0.69
2020 Fang X, Wu Z, Raitskin O, Webb K, Voigt P, Lu T, Howard M, Dean C. The 3' processing of antisense RNAs physically links to chromatin-based transcriptional control. Proceedings of the National Academy of Sciences of the United States of America. PMID 32541063 DOI: 10.1073/Pnas.2007268117  0.677
2020 Qüesta JI, Antoniou-Kourounioti RL, Rosa S, Li P, Duncan S, Whittaker C, Howard M, Dean C. Noncoding SNPs influence a distinct phase of Polycomb silencing to destabilize long-term epigenetic memory at . Genes & Development. PMID 32001513 DOI: 10.1101/Gad.333245.119  0.375
2019 Wu Z, Fang X, Zhu D, Dean C. Autonomous pathway: FLOWERING LOCUS C repression through an antisense-mediated chromatin silencing mechanism. Plant Physiology. PMID 31740502 DOI: 10.1104/Pp.19.01009  0.716
2019 Costa S, Dean C. Storing memories: the distinct phases of Polycomb-mediated silencing of . Biochemical Society Transactions. PMID 31278155 DOI: 10.1042/Bst20190255  0.488
2019 Fang X, Wang L, Ishikawa R, Li Y, Fiedler M, Liu F, Calder G, Rowan B, Weigel D, Li P, Dean C. Arabidopsis FLL2 promotes liquid-liquid phase separation of polyadenylation complexes. Nature. PMID 31043738 DOI: 10.1038/S41586-019-1165-8  0.627
2019 Levy YY, Dean C. The transition to flowering The Plant Cell. 10: 1973-90. PMID 9836739 DOI: 10.1105/Tpc.10.12.1973  0.353
2018 Antoniou-Kourounioti RL, Hepworth J, Heckmann A, Duncan S, Qüesta J, Rosa S, Säll T, Holm S, Dean C, Howard M. Temperature Sensing Is Distributed throughout the Regulatory Network that Controls FLC Epigenetic Silencing in Vernalization. Cell Systems. PMID 30503646 DOI: 10.1016/J.Cels.2018.10.011  0.366
2018 Hepworth J, Antoniou-Kourounioti RL, Bloomer RH, Selga C, Berggren K, Cox D, Collier Harris BR, Irwin JA, Holm S, Säll T, Howard M, Dean C. Absence of warmth permits epigenetic memory of winter in Arabidopsis. Nature Communications. 9: 639. PMID 29434233 DOI: 10.1038/S41467-018-03065-7  0.361
2017 Berry S, Rosa S, Howard M, Bühler M, Dean C. Disruption of an RNA-binding hinge region abolishes LHP1-mediated epigenetic repression. Genes & Development. 31: 2115-2120. PMID 29212661 DOI: 10.1101/Gad.305227.117  0.402
2017 Bloomer RH, Dean C. Fine-tuning timing: natural variation informs the mechanistic basis of the switch to flowering in Arabidopsis thaliana. Journal of Experimental Botany. PMID 28992087 DOI: 10.1093/Jxb/Erx270  0.34
2017 Yang H, Berry S, Olsson TSG, Hartley M, Howard M, Dean C. Distinct phases of Polycomb silencing to hold epigenetic memory of cold in Arabidopsis. Science (New York, N.Y.). PMID 28818969 DOI: 10.1126/Science.Aan1121  0.727
2017 Whittaker C, Dean C. The FLC Locus: A Platform for Discoveries in Epigenetics and Adaptation. Annual Review of Cell and Developmental Biology. PMID 28693387 DOI: 10.1146/Annurev-Cellbio-100616-060546  0.468
2017 Ietswaart R, Rosa S, Wu Z, Dean C, Howard M. Cell-Size-Dependent Transcription of FLC and Its Antisense Long Non-coding RNA COOLAIR Explain Cell-to-Cell Expression Variation. Cell Systems. PMID 28624615 DOI: 10.1016/J.Cels.2017.05.010  0.388
2017 Berry S, Dean C, Howard M. Slow Chromatin Dynamics Allow Polycomb Target Genes to Filter Fluctuations in Transcription Factor Activity. Cell Systems. PMID 28342717 DOI: 10.1016/J.Cels.2017.02.013  0.443
2016 Duncan S, Olsson TS, Hartley M, Dean C, Rosa S. A method for detecting single mRNA molecules in Arabidopsis thaliana. Plant Methods. 12: 13. PMID 28035231 DOI: 10.1186/S13007-016-0114-X  0.3
2016 Rosa S, Duncan S, Dean C. Mutually exclusive sense-antisense transcription at FLC facilitates environmentally induced gene repression. Nature Communications. 7: 13031. PMID 27713408 DOI: 10.1038/Ncomms13031  0.477
2016 Hawkes EJ, Hennelly SP, Novikova IV, Irwin JA, Dean C, Sanbonmatsu KY. COOLAIR Antisense RNAs Form Evolutionarily Conserved Elaborate Secondary Structures. Cell Reports. 16: 3087-96. PMID 27653675 DOI: 10.1016/J.Celrep.2016.08.045  0.339
2016 Yang H, Howard M, Dean C. Physical coupling of activation and derepression activities to maintain an active transcriptional state at FLC. Proceedings of the National Academy of Sciences of the United States of America. PMID 27482092 DOI: 10.1073/Pnas.1605733113  0.72
2016 Qüesta JI, Song J, Geraldo N, An H, Dean C. Arabidopsis transcriptional repressor VAL1 triggers Polycomb silencing at FLC during vernalization. Science (New York, N.Y.). 353: 485-8. PMID 27471304 DOI: 10.1126/Science.Aaf7354  0.5
2016 Irwin JA, Soumpourou E, Lister C, Ligthart JD, Kennedy S, Dean C. Nucleotide polymorphism affecting FLC expression underpins heading date variation in horticultural brassicas. The Plant Journal : For Cell and Molecular Biology. PMID 27232938 DOI: 10.1111/Tpj.13221  0.316
2015 Wu Z, Zhu D, Lin X, Miao J, Gu L, Deng X, Yang Q, Sun K, Zhu D, Cao X, Tsuge T, Dean C, Aoyama T, Gu H, Qu LJ. RNA-binding proteins At RZ-1B and At RZ-1C play a critical role in regulation of pre-mRNA splicing and gene expression during Arabidopsis development. The Plant Cell. PMID 26721863 DOI: 10.1105/Tpc.15.00949  0.396
2015 Wu Z, Ietswaart R, Liu F, Yang H, Howard M, Dean C. Quantitative regulation of FLC via coordinated transcriptional initiation and elongation. Proceedings of the National Academy of Sciences of the United States of America. PMID 26699513 DOI: 10.1073/Pnas.1518369112  0.743
2015 Dean C, Vicente C. An interview with Caroline Dean. Development (Cambridge, England). 142: 2725-6. PMID 26286939 DOI: 10.1242/Dev.127548  0.389
2015 Duncan S, Holm S, Questa J, Irwin J, Grant A, Dean C. Seasonal shift in timing of vernalization as an adaptation to extreme winter. Elife. 4. PMID 26203563 DOI: 10.7554/Elife.06620  0.309
2015 Hepworth J, Dean C. Flowering Locus C's Lessons: Conserved Chromatin Switches Underpinning Developmental Timing and Adaptation. Plant Physiology. 168: 1237-45. PMID 26149571 DOI: 10.1104/Pp.15.00496  0.456
2015 Berry S, Hartley M, Olsson TS, Dean C, Howard M. Local chromatin environment of a Polycomb target gene instructs its own epigenetic inheritance. Elife. 4. PMID 25955967 DOI: 10.7554/Elife.07205  0.444
2015 Berry S, Dean C. Environmental perception and epigenetic memory: mechanistic insight through FLC. The Plant Journal : For Cell and Molecular Biology. 83: 133-48. PMID 25929799 DOI: 10.1111/Tpj.12869  0.468
2015 Li P, Tao Z, Dean C. Phenotypic evolution through variation in splicing of the noncoding RNA COOLAIR. Genes & Development. 29: 696-701. PMID 25805848 DOI: 10.1101/Gad.258814.115  0.413
2015 Angel A, Song J, Yang H, Questa JI, Dean C, Howard M. Vernalizing cold is registered digitally at FLC. Proceedings of the National Academy of Sciences of the United States of America. 112: 4146-51. PMID 25775579 DOI: 10.1073/Pnas.1503100112  0.678
2015 Zhu D, Rosa S, Dean C. Nuclear organization changes and the epigenetic silencing of FLC during vernalization. Journal of Molecular Biology. 427: 659-69. PMID 25180639 DOI: 10.1016/J.Jmb.2014.08.025  0.455
2015 Berry S, Hartley M, Olsson TSG, Dean C, Howard M. Author response: Local chromatin environment of a Polycomb target gene instructs its own epigenetic inheritance Elife. DOI: 10.7554/Elife.07205.016  0.362
2014 Csorba T, Questa JI, Sun Q, Dean C. Antisense COOLAIR mediates the coordinated switching of chromatin states at FLC during vernalization. Proceedings of the National Academy of Sciences of the United States of America. 111: 16160-5. PMID 25349421 DOI: 10.1073/Pnas.1419030111  0.737
2014 Crevillén P, Yang H, Cui X, Greeff C, Trick M, Qiu Q, Cao X, Dean C. Epigenetic reprogramming that prevents transgenerational inheritance of the vernalized state. Nature. 515: 587-90. PMID 25219852 DOI: 10.1038/Nature13722  0.738
2014 Baulcombe DC, Dean C. Epigenetic regulation in plant responses to the environment. Cold Spring Harbor Perspectives in Biology. 6: a019471. PMID 25183832 DOI: 10.1101/Cshperspect.A019471  0.448
2014 Yang H, Howard M, Dean C. Antagonistic roles for H3K36me3 and H3K27me3 in the cold-induced epigenetic switch at Arabidopsis FLC. Current Biology : Cb. 24: 1793-7. PMID 25065750 DOI: 10.1016/J.Cub.2014.06.047  0.724
2014 Li P, Filiault D, Box MS, Kerdaffrec E, van Oosterhout C, Wilczek AM, Schmitt J, McMullan M, Bergelson J, Nordborg M, Dean C. Multiple FLC haplotypes defined by independent cis-regulatory variation underpin life history diversity in Arabidopsis thaliana. Genes & Development. 28: 1635-40. PMID 25035417 DOI: 10.1101/Gad.245993.114  0.369
2014 Wang ZW, Wu Z, Raitskin O, Sun Q, Dean C. Antisense-mediated FLC transcriptional repression requires the P-TEFb transcription elongation factor. Proceedings of the National Academy of Sciences of the United States of America. 111: 7468-73. PMID 24799695 DOI: 10.1073/Pnas.1406635111  0.719
2014 Marquardt S, Raitskin O, Wu Z, Liu F, Sun Q, Dean C. Functional consequences of splicing of the antisense transcript COOLAIR on FLC transcription. Molecular Cell. 54: 156-65. PMID 24725596 DOI: 10.1016/J.Molcel.2014.03.026  0.718
2014 Song J, Rutjens B, Dean C. Detecting histone modifications in plants. Methods in Molecular Biology (Clifton, N.J.). 1112: 165-75. PMID 24478014 DOI: 10.1007/978-1-62703-773-0_11  0.46
2013 Song J, Irwin J, Dean C. Remembering the prolonged cold of winter. Current Biology : Cb. 23: R807-11. PMID 24028964 DOI: 10.1016/J.Cub.2013.07.027  0.368
2013 Rosa S, De Lucia F, Mylne JS, Zhu D, Ohmido N, Pendle A, Kato N, Shaw P, Dean C. Physical clustering of FLC alleles during Polycomb-mediated epigenetic silencing in vernalization. Genes & Development. 27: 1845-50. PMID 24013499 DOI: 10.1101/Gad.221713.113  0.381
2013 Sun Q, Csorba T, Skourti-Stathaki K, Proudfoot NJ, Dean C. R-loop stabilization represses antisense transcription at the Arabidopsis FLC locus. Science (New York, N.Y.). 340: 619-21. PMID 23641115 DOI: 10.1126/Science.1234848  0.692
2013 Crevillén P, Sonmez C, Wu Z, Dean C. A gene loop containing the floral repressor FLC is disrupted in the early phase of vernalization. The Embo Journal. 32: 140-8. PMID 23222483 DOI: 10.1038/Emboj.2012.324  0.47
2012 Song J, Angel A, Howard M, Dean C. Vernalization - a cold-induced epigenetic switch. Journal of Cell Science. 125: 3723-31. PMID 22935652 DOI: 10.1242/Jcs.084764  0.445
2012 Coustham V, Li P, Strange A, Lister C, Song J, Dean C. Quantitative modulation of polycomb silencing underlies natural variation in vernalization. Science (New York, N.Y.). 337: 584-7. PMID 22798408 DOI: 10.1126/Science.1221881  0.409
2012 Ietswaart R, Wu Z, Dean C. Flowering time control: another window to the connection between antisense RNA and chromatin. Trends in Genetics : Tig. 28: 445-53. PMID 22785023 DOI: 10.1016/J.Tig.2012.06.002  0.525
2012 Liu F, Bakht S, Dean C. Cotranscriptional role for Arabidopsis DICER-LIKE 4 in transcription termination. Science (New York, N.Y.). 335: 1621-3. PMID 22461611 DOI: 10.1126/Science.1214402  0.477
2012 Irwin JA, Lister C, Soumpourou E, Zhang Y, Howell EC, Teakle G, Dean C. Functional alleles of the flowering time regulator FRIGIDA in the Brassica oleracea genome. Bmc Plant Biology. 12: 21. PMID 22333192 DOI: 10.1186/1471-2229-12-21  0.432
2012 Sonmez C, Dean C. Transcription beyond borders has downstream consequences. Rna Biology. 9: 143-7. PMID 22258223 DOI: 10.4161/Rna.18668  0.454
2011 Angel A, Song J, Dean C, Howard M. A Polycomb-based switch underlying quantitative epigenetic memory. Nature. 476: 105-8. PMID 21785438 DOI: 10.1038/Nature10241  0.417
2011 Strange A, Li P, Lister C, Anderson J, Warthmann N, Shindo C, Irwin J, Nordborg M, Dean C. Major-effect alleles at relatively few loci underlie distinct vernalization and flowering variation in Arabidopsis accessions. Plos One. 6: e19949. PMID 21625501 DOI: 10.1371/Journal.Pone.0019949  0.343
2011 Sonmez C, Bäurle I, Magusin A, Dreos R, Laubinger S, Weigel D, Dean C. RNA 3' processing functions of Arabidopsis FCA and FPA limit intergenic transcription. Proceedings of the National Academy of Sciences of the United States of America. 108: 8508-13. PMID 21536901 DOI: 10.1073/Pnas.1105334108  0.465
2011 Box MS, Coustham V, Dean C, Mylne JS. Protocol: A simple phenol-based method for 96-well extraction of high quality RNA from Arabidopsis. Plant Methods. 7: 7. PMID 21396125 DOI: 10.1186/1746-4811-7-7  0.345
2011 De Lucia F, Dean C. Long non-coding RNAs and chromatin regulation. Current Opinion in Plant Biology. 14: 168-73. PMID 21168359 DOI: 10.1016/J.Pbi.2010.11.006  0.473
2011 Crevillén P, Dean C. Regulation of the floral repressor gene FLC: the complexity of transcription in a chromatin context. Current Opinion in Plant Biology. 14: 38-44. PMID 20884277 DOI: 10.1016/J.Pbi.2010.08.015  0.468
2010 Simpson GG, Laurie RE, Dijkwel PP, Quesada V, Stockwell PA, Dean C, Macknight RC. Noncanonical translation initiation of the Arabidopsis flowering time and alternative polyadenylation regulator FCA. The Plant Cell. 22: 3764-77. PMID 21075770 DOI: 10.1105/Tpc.110.077990  0.479
2010 Atwell S, Huang YS, Vilhjálmsson BJ, Willems G, Horton M, Li Y, Meng D, Platt A, Tarone AM, Hu TT, Jiang R, Muliyati NW, Zhang X, Amer MA, Baxter I, ... ... Dean C, et al. Genome-wide association study of 107 phenotypes in Arabidopsis thaliana inbred lines. Nature. 465: 627-31. PMID 20336072 DOI: 10.1038/Nature08800  0.311
2010 Liu F, Marquardt S, Lister C, Swiezewski S, Dean C. Targeted 3' processing of antisense transcripts triggers Arabidopsis FLC chromatin silencing. Science (New York, N.Y.). 327: 94-7. PMID 19965720 DOI: 10.1126/Science.1180278  0.468
2009 Swiezewski S, Liu F, Magusin A, Dean C. Cold-induced silencing by long antisense transcripts of an Arabidopsis Polycomb target. Nature. 462: 799-802. PMID 20010688 DOI: 10.1038/Nature08618  0.509
2009 Manzano D, Marquardt S, Jones AM, Bäurle I, Liu F, Dean C. Altered interactions within FY/AtCPSF complexes required for Arabidopsis FCA-mediated chromatin silencing. Proceedings of the National Academy of Sciences of the United States of America. 106: 8772-7. PMID 19439664 DOI: 10.1073/Pnas.0903444106  0.419
2009 Geraldo N, Bäurle I, Kidou S, Hu X, Dean C. FRIGIDA delays flowering in Arabidopsis via a cotranscriptional mechanism involving direct interaction with the nuclear cap-binding complex. Plant Physiology. 150: 1611-8. PMID 19429606 DOI: 10.1104/Pp.109.137448  0.457
2009 Choi J, Hyun Y, Kang MJ, In Yun H, Yun JY, Lister C, Dean C, Amasino RM, Noh B, Noh YS, Choi Y. Resetting and regulation of Flowering Locus C expression during Arabidopsis reproductive development. The Plant Journal : For Cell and Molecular Biology. 57: 918-31. PMID 19121105 DOI: 10.1111/J.1365-313X.2008.03776.X  0.462
2009 Dean C. PL-02 Vernalization – Cold-mediated epigenetic regulation of a developmental switch Mechanisms of Development. 126: S1. DOI: 10.1016/J.Mod.2009.06.1073  0.382
2009 Liu F, Marquardt S, Dean C. RNA processing mediated transcriptional silencing of FLC in flowering time regulation Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 153: S196. DOI: 10.1016/J.Cbpa.2009.04.441  0.42
2008 Bender J, Benfey P, Bergmann D, Borevitz J, Coruzzi G, Dangl J, Dean C, Ecker J, Estelle M, Glazebrook J, Grant S, Guerinot ML, Gutierrez R, Long J, Nordborg M, et al. 2020 vision for biology: the role of plants in addressing grand challenges in biology. Molecular Plant. 1: 561-3. PMID 19825561 DOI: 10.1093/Mp/Ssn040  0.353
2008 De Lucia F, Crevillen P, Jones AM, Greb T, Dean C. A PHD-polycomb repressive complex 2 triggers the epigenetic silencing of FLC during vernalization. Proceedings of the National Academy of Sciences of the United States of America. 105: 16831-6. PMID 18854416 DOI: 10.1073/Pnas.0808687105  0.724
2008 Bäurle I, Dean C. Differential interactions of the autonomous pathway RRM proteins and chromatin regulators in the silencing of Arabidopsis targets. Plos One. 3: e2733. PMID 18628965 DOI: 10.1371/Journal.Pone.0002733  0.456
2008 Pien S, Fleury D, Mylne JS, Crevillen P, Inzé D, Avramova Z, Dean C, Grossniklaus U. ARABIDOPSIS TRITHORAX1 dynamically regulates FLOWERING LOCUS C activation via histone 3 lysine 4 trimethylation. The Plant Cell. 20: 580-8. PMID 18375656 DOI: 10.1105/Tpc.108.058172  0.493
2008 Sheldon CC, Hills MJ, Lister C, Dean C, Dennis ES, Peacock WJ. Resetting of FLOWERING LOCUS C expression after epigenetic repression by vernalization. Proceedings of the National Academy of Sciences of the United States of America. 105: 2214-9. PMID 18250331 DOI: 10.1073/Pnas.0711453105  0.402
2007 Liu F, Quesada V, Crevillén P, Bäurle I, Swiezewski S, Dean C. The Arabidopsis RNA-binding protein FCA requires a lysine-specific demethylase 1 homolog to downregulate FLC. Molecular Cell. 28: 398-407. PMID 17996704 DOI: 10.1016/J.Molcel.2007.10.018  0.457
2007 Bäurle I, Smith L, Baulcombe DC, Dean C. Widespread role for the flowering-time regulators FCA and FPA in RNA-mediated chromatin silencing. Science (New York, N.Y.). 318: 109-12. PMID 17916737 DOI: 10.1126/Science.1146565  0.456
2007 Swiezewski S, Crevillen P, Liu F, Ecker JR, Jerzmanowski A, Dean C. Small RNA-mediated chromatin silencing directed to the 3' region of the Arabidopsis gene encoding the developmental regulator, FLC. Proceedings of the National Academy of Sciences of the United States of America. 104: 3633-8. PMID 17360694 DOI: 10.1073/Pnas.0611459104  0.425
2007 Greb T, Mylne JS, Crevillen P, Geraldo N, An H, Gendall AR, Dean C. The PHD finger protein VRN5 functions in the epigenetic silencing of Arabidopsis FLC. Current Biology : Cb. 17: 73-8. PMID 17174094 DOI: 10.1016/J.Cub.2006.11.052  0.747
2006 Shindo C, Lister C, Crevillen P, Nordborg M, Dean C. Variation in the epigenetic silencing of FLC contributes to natural variation in Arabidopsis vernalization response. Genes & Development. 20: 3079-83. PMID 17114581 DOI: 10.1101/Gad.405306  0.433
2006 Marquardt S, Boss PK, Hadfield J, Dean C. Additional targets of the Arabidopsis autonomous pathway members, FCA and FY. Journal of Experimental Botany. 57: 3379-86. PMID 16940039 DOI: 10.1093/Jxb/Erl073  0.441
2006 Bäurle I, Dean C. The timing of developmental transitions in plants. Cell. 125: 655-64. PMID 16713560 DOI: 10.1016/J.Cell.2006.05.005  0.37
2006 Mylne JS, Barrett L, Tessadori F, Mesnage S, Johnson L, Bernatavichute YV, Jacobsen SE, Fransz P, Dean C. LHP1, the Arabidopsis homologue of HETEROCHROMATIN PROTEIN1, is required for epigenetic silencing of FLC. Proceedings of the National Academy of Sciences of the United States of America. 103: 5012-7. PMID 16549797 DOI: 10.1073/Pnas.0507427103  0.623
2005 Winichayakul S, Beswick NL, Dean C, Macknight RC. Components of the Arabidopsis autonomous floral promotion pathway, FCA and FY, are conserved in monocots. Functional Plant Biology : Fpb. 32: 345-355. PMID 32689136 DOI: 10.1071/Fp04245  0.436
2005 Aranzana MJ, Kim S, Zhao K, Bakker E, Horton M, Jakob K, Lister C, Molitor J, Shindo C, Tang C, Toomajian C, Traw B, Zheng H, Bergelson J, Dean C, et al. Genome-wide association mapping in Arabidopsis identifies previously known flowering time and pathogen resistance genes. Plos Genetics. 1: e60. PMID 16292355 DOI: 10.1371/Journal.Pgen.0010060  0.33
2005 Quesada V, Dean C, Simpson GG. Regulated RNA processing in the control of Arabidopsis flowering. The International Journal of Developmental Biology. 49: 773-80. PMID 16096981 DOI: 10.1387/ijdb.051995vq  0.394
2005 Henderson IR, Liu F, Drea S, Simpson GG, Dean C. An allelic series reveals essential roles for FY in plant development in addition to flowering-time control. Development (Cambridge, England). 132: 3597-607. PMID 16033802 DOI: 10.1242/Dev.01924  0.615
2005 Shindo C, Aranzana MJ, Lister C, Baxter C, Nicholls C, Nordborg M, Dean C. Role of FRIGIDA and FLOWERING LOCUS C in determining variation in flowering time of Arabidopsis. Plant Physiology. 138: 1163-73. PMID 15908596 DOI: 10.1104/Pp.105.061309  0.399
2005 Aranzana MJ, Kim S, Zhao K, Bakker E, Horton M, Jakob K, Lister C, Molitor J, Shindo C, Tang C, Toomajian C, Traw B, Zheng H, Bergelson J, Dean C, et al. Genome-wide association mapping in Arabidopsis thaliana identifies previously known genes responsible for variation in flowering time and pathogen resistance Plos Genetics. DOI: 10.1371/Journal.Pgen.0010060.Eor  0.331
2004 Mylne J, Greb T, Lister C, Dean C. Epigenetic regulation in the control of flowering. Cold Spring Harbor Symposia On Quantitative Biology. 69: 457-64. PMID 16117681 DOI: 10.1101/Sqb.2004.69.457  0.717
2004 Henderson IR, Dean C. Control of Arabidopsis flowering: the chill before the bloom. Development (Cambridge, England). 131: 3829-38. PMID 15289433 DOI: 10.1242/Dev.01294  0.625
2004 Simpson GG, Quesada V, Henderson IR, Dijkwel PP, Macknight R, Dean C. RNA processing and Arabidopsis flowering time control. Biochemical Society Transactions. 32: 565-6. PMID 15270676 DOI: 10.1042/Bst0320565  0.433
2004 Boss PK, Bastow RM, Mylne JS, Dean C. Multiple pathways in the decision to flower: enabling, promoting, and resetting. The Plant Cell. 16: S18-31. PMID 15037730 DOI: 10.1105/Tpc.015958  0.736
2004 Bastow R, Mylne JS, Lister C, Lippman Z, Martienssen RA, Dean C. Vernalization requires epigenetic silencing of FLC by histone methylation. Nature. 427: 164-7. PMID 14712277 DOI: 10.1038/Nature02269  0.769
2003 Bastow R, Dean C. Plant sciences. Deciding when to flower. Science (New York, N.Y.). 302: 1695-6. PMID 14657484 DOI: 10.1126/Science.1092862  0.75
2003 Henderson IR, Shindo C, Dean C. The need for winter in the switch to flowering. Annual Review of Genetics. 37: 371-92. PMID 14616066 DOI: 10.1146/Annurev.Genet.37.110801.142640  0.631
2003 Murtas G, Reeves PH, Fu YF, Bancroft I, Dean C, Coupland G. A Nuclear Protease Required for Flowering-Time Regulation in Arabidopsis Reduces the Abundance of SMALL UBIQUITIN-RELATED MODIFIER Conjugates Plant Cell. 15: 2308-2319. PMID 14507998 DOI: 10.1105/Tpc.015487  0.417
2003 Simpson GG, Dijkwel PP, Quesada V, Henderson I, Dean C. FY is an RNA 3' end-processing factor that interacts with FCA to control the Arabidopsis floral transition. Cell. 113: 777-87. PMID 12809608 DOI: 10.1016/S0092-8674(03)00425-2  0.582
2003 Gazzani S, Gendall AR, Lister C, Dean C. Analysis of the molecular basis of flowering time variation in Arabidopsis accessions. Plant Physiology. 132: 1107-14. PMID 12805638 DOI: 10.1104/Pp.103.021212  0.347
2003 Muskett PR, Clissold L, Marocco A, Springer PS, Martienssen R, Dean C. A resource of mapped dissociation launch pads for targeted insertional mutagenesis in the Arabidopsis genome. Plant Physiology. 132: 506-16. PMID 12805583 DOI: 10.1104/Pp.102.016535  0.33
2003 Quesada V, Macknight R, Dean C, Simpson GG. Autoregulation of FCA pre-mRNA processing controls Arabidopsis flowering time. The Embo Journal. 22: 3142-52. PMID 12805228 DOI: 10.1093/Emboj/Cdg305  0.444
2002 Bastow R, Dean C. The molecular basis of photoperiodism. Developmental Cell. 3: 461-2. PMID 12408794 DOI: 10.1016/S1534-5807(02)00296-4  0.736
2002 Levy YY, Mesnage S, Mylne JS, Gendall AR, Dean C. Multiple roles of Arabidopsis VRN1 in vernalization and flowering time control. Science (New York, N.Y.). 297: 243-6. PMID 12114624 DOI: 10.1126/Science.1072147  0.409
2002 Macknight R, Duroux M, Laurie R, Dijkwel P, Simpson G, Dean C. Functional significance of the alternative transcript processing of the Arabidopsis floral promoter FCA Plant Cell. 14: 877-888. PMID 11971142 DOI: 10.1105/Tpc.010456  0.465
2002 Simpson GG, Dean C. Arabidopsis, the Rosetta stone of flowering time? Science (New York, N.Y.). 296: 285-9. PMID 11951029 DOI: 10.1126/Science.296.5566.285  0.387
2002 Gendall AR, Levy YY, Wilson A, Dean C. The VERNALIZATION 2 gene mediates the epigenetic regulation of vernalization in Arabidopsis. Cell. 107: 525-35. PMID 11719192 DOI: 10.1016/S0092-8674(01)00573-6  0.477
2000 Simpson GG, Dean C. Environmental-dependent acceleration of a developmental switch: the floral transition. Science's Stke : Signal Transduction Knowledge Environment. 2000: pe1. PMID 11752590 DOI: 10.1126/Stke.2000.18.Pe1  0.383
2000 Dean C. Big ideas from a small plant Science. 290: 2071. PMID 11187829 DOI: 10.1126/Science.290.5499.2071  0.397
2000 Johanson U, West J, Lister C, Michaels S, Amasino R, Dean C. Molecular analysis of FRIGIDA, a major determinant of natural variation in Arabidopsis flowering time Science. 290: 344-347. PMID 11030654 DOI: 10.1126/Science.290.5490.344  0.382
2000 Yamanaka T, Ohta T, Takahashi M, Meshi T, Schmidt R, Dean C, Naito S, Ishikawa M. TOM1, an Arabidopsis gene required for efficient multiplication of a tobamovirus, encodes a putative transmembrane protein Proceedings of the National Academy of Sciences of the United States of America. 97: 10107-10112. PMID 10944200 DOI: 10.1073/Pnas.170295097  0.352
2000 Dean C, Gendall T, Levy Y, Lister C, Simpson G, Torney K, Dijkwel P, Duroux M, Hutchison C, Johanson U, Macknight R, Smart B, Sivadon P, West J. Molecular Analysis Of Flowering Time And Vernalization Response In Arabidopsis, A Minireview Developments in Plant Genetics and Breeding. 6: 115-121. DOI: 10.1016/S0168-7972(00)80111-5  0.398
1999 Simpson GG, Gendall AR, Dean C. When to switch to flowering. Annual Review of Cell and Developmental Biology. 15: 519-50. PMID 10611971 DOI: 10.1146/Annurev.Cellbio.15.1.519  0.425
1999 Bhatt AM, Lister C, Page T, Fransz P, Findlay K, Jones GH, Dickinson HG, Dean C. The DIF1 gene of Arabidopsis is required for meiotic chromosome segregation and belongs to the REC8/RAD21 cohesin gene family. The Plant Journal : For Cell and Molecular Biology. 19: 463-72. PMID 10504568 DOI: 10.1046/J.1365-313X.1999.00548.X  0.354
1999 Marrison JL, Rutherford SM, Robertson EJ, Lister C, Dean C, Leech RM. The distinctive roles of five different ARC genes in the chloroplast division process in Arabidopsis. The Plant Journal : For Cell and Molecular Biology. 18: 651-62. PMID 10417716 DOI: 10.1046/J.1365-313X.1999.00500.X  0.37
1999 Sherson S, Gy I, Medd J, Schmidt R, Dean C, Kreis M, Lecharny A, Cobbett C. The arabinose kinase, ARA1, gene of Arabidopsis is a novel member of the galactose kinase gene family. Plant Molecular Biology. 39: 1003-12. PMID 10344205 DOI: 10.1023/A:1006181908753  0.322
1999 Page T, Macknight R, Yang CH, Dean C. Genetic interactions of the Arabidopsis flowering time gene FCA, with genes regulating floral initiation. The Plant Journal : For Cell and Molecular Biology. 17: 231-9. PMID 10097382 DOI: 10.1046/J.1365-313X.1999.00364.X  0.415
1999 Levy YY, Dean C. Control of flowering time. Current Opinion in Plant Biology. 1: 49-54. PMID 10066558 DOI: 10.1016/S1369-5266(98)80127-1  0.372
1998 Meinke DW, Cherry JM, Dean C, Rounsley SD, Koornneef M. Arabidopsis thaliana: A Model Plant for Genome Analysis Science. 282: 662-682. PMID 9784120 DOI: 10.1126/Science.282.5389.662  0.375
1998 Bhatt AM, Lister C, Crawford N, Dean C. The Transposition Frequency of Tag1 Elements Is Increased in Transgenic Arabidopsis Lines The Plant Cell. 10: 427-434. PMID 9501115 DOI: 10.1105/Tpc.10.3.427  0.323
1998 Bevan M, Bancroft I, Bent E, Love K, Goodman H, Dean C, Bergkamp R, Dirkse W, Van Staveren M, Stiekema W, Drost L, Ridley P, Hudson SA, Patel K, Murphy G, et al. Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana. Nature. 391: 485-8. PMID 9461215 DOI: 10.1038/35140  0.347
1997 Parker JE, Coleman MJ, Szabò V, Frost LN, Schmidt R, van der Biezen EA, Moores T, Dean C, Daniels MJ, Jones JD. The Arabidopsis downy mildew resistance gene RPP5 shares similarity to the toll and interleukin-1 receptors with N and L6. The Plant Cell. 9: 879-94. PMID 9212464 DOI: 10.1105/Tpc.9.6.879  0.34
1997 Jarvis P, Belzile F, Dean C. Inefficient and incorrect processing of the Ac transposase transcript in iae1 and wild-type Arabidopsis thaliana Plant Journal. 11: 921-931. PMID 9193066 DOI: 10.1046/J.1365-313X.1997.11050921.X  0.387
1997 Macknight R, Bancroft I, Page T, Lister C, Schmidt R, Love K, Westphal L, Murphy G, Sherson S, Cobbett C, Dean C. FCA, a gene controlling flowering time in Arabidopsis, encodes a protein containing RNA-binding domains. Cell. 89: 737-45. PMID 9182761 DOI: 10.1016/S0092-8674(00)80256-1  0.466
1997 Dietrich RA, Richberg MH, Schmidt R, Dean C, Dangl JL. A novel zinc finger protein is encoded by the Arabidopsis LSD1 gene and functions as a negative regulator of plant cell death Cell. 88: 685-694. PMID 9054508 DOI: 10.1016/S0092-8674(00)81911-X  0.387
1996 Chandler J, Wilson A, Dean C. Arabidopsis mutants showing an altered response to vernalization. Plant Journal. 10: 637-644. PMID 8998499 DOI: 10.1046/J.1365-313X.1996.10040637.X  0.367
1996 Bhatt AM, Page T, Lawson EJ, Lister C, Dean C. Use of Ac as an insertional mutagen in Arabidopsis. The Plant Journal : For Cell and Molecular Biology. 9: 935-45. PMID 8696369 DOI: 10.1046/J.1365-313X.1996.9060935.X  0.317
1996 Wilson A, Dean C. Analysis of the molecular basis of vernalization inArabidopsis thaliana Seminars in Cell & Developmental Biology. 7: 435-440. DOI: 10.1006/Scdb.1996.0054  0.459
1995 Sundaresan V, Springer P, Volpe T, Haward S, Jones JD, Dean C, Ma H, Martienssen R. Patterns of gene action in plant development revealed by enhancer trap and gene trap transposable elements. Genes & Development. 9: 1797-810. PMID 7622040 DOI: 10.1101/Gad.9.14.1797  0.39
1995 Clarke JH, Mithen R, Brown JK, Dean C. QTL analysis of flowering time in Arabidopsis thaliana. Molecular & General Genetics : Mgg. 248: 278-86. PMID 7565589 DOI: 10.1007/Bf02191594  0.337
1995 Goodman HM, Ecker JR, Dean C. The genome of Arabidopsis thaliana. Proceedings of the National Academy of Sciences of the United States of America. 92: 10831-5. PMID 7479893 DOI: 10.1073/Pnas.92.24.10831  0.36
1995 Mithen R, Clarke J, Lister C, Dean C. Genetics of aliphatic glucosinolates. III. Side chain structure of aliphatic glucosinolates in Arabidopsis thaliana Heredity. 74: 210-215. DOI: 10.1038/Hdy.1995.29  0.324
1994 Clarke JH, Dean C. Mapping FRI, a locus controlling flowering time and vernalization response in Arabidopsis thaliana. Molecular & General Genetics : Mgg. 242: 81-9. PMID 7904045 DOI: 10.1007/Bf00277351  0.317
1994 Lawson EJ, Scofield SR, Sjodin C, Jones JD, Dean C. Modification of the 5' untranslated leader region of the maize Activator element leads to increased activity in Arabidopsis. Molecular & General Genetics : Mgg. 245: 608-15. PMID 7808411 DOI: 10.1007/Bf00282223  0.337
1994 Martínez-Zapater JM, Coupland G, Dean C, Koornneef M. 16 The Transition to Flowering in Arabidopsis Cold Spring Harbor Monograph Archive. 27: 403-433. DOI: 10.1101/087969428.27.403  0.354
1994 Chandler J, Dean C. Factors influencing the vernalization response and flowering time of late flowering mutants ofArabidopsis thaliana(L.) Heynh. Journal of Experimental Botany. 45: 1279-1288. DOI: 10.1093/Jxb/45.9.1279  0.3
1994 Dean C, Bancroft I. Development of an efficient transposon tagging system in Arabidopsis thaliana. Symposia of the Society For Experimental Biology. 45: 527-537. DOI: 10.1007/978-3-642-78852-9_48  0.312
1993 Bancroft I, Dean C. Factors affecting the excision frequency of the maize transposable element Ds in Arabidopsis thaliana. Molecular & General Genetics : Mgg. 240: 65-72. PMID 8393513 DOI: 10.1007/Bf00276885  0.323
1993 Bancroft I, Jones JDG, Dean C. Heterologous transposon tagging of the DRL1 locus in Arabidopsis. The Plant Cell. 5: 631-638. PMID 8392411 DOI: 10.1105/Tpc.5.6.631  0.362
1993 Tsay YF, Frank MJ, Page T, Dean C, Crawford NM. Identification of a mobile endogenous transposon in Arabidopsis thaliana. Science (New York, N.Y.). 260: 342-4. PMID 8385803 DOI: 10.1126/Science.8385803  0.402
1993 Dean C. Advantages of Arabidopsis for cloning plant genes Philosophical Transactions of the Royal Society B. 342: 189-195. DOI: 10.1098/Rstb.1993.0146  0.402
1993 Parker JE, Szabo V, Staskawicz BJ, Lister C, Dean C, Daniels MJ, Jones JD. Phenotypic characterization and molecular mapping of the Arabidopsis thaliana locus RPP5, determining disease resistance to Peronospora parasitica The Plant Journal. 4: 821-831. DOI: 10.1046/J.1365-313X.1993.04050821.X  0.342
1993 Schmidt R, Dean C. Genes and genomes: Towards construction of an overlapping YAC library of theArabidopsis thaliana genome Bioessays. 15: 63-69. DOI: 10.1002/Bies.950150110  0.318
1992 Bancroft I, Bhatt AM, Sjodin C, Scofield S, Jones JD, Dean C. Development of an efficient two-element transposon tagging system in Arabidopsis thaliana. Molecular & General Genetics : Mgg. 233: 449-61. PMID 1320189 DOI: 10.1007/Bf00265443  0.337
1991 Martineau B, Smith HJ, Dean C, Dunsmuir P, Bedbrook J, Mets LJ. Expression of a C3 plant Rubisco SSU gene in regenerated C4 Flaveria plants. Plant Molecular Biology. 13: 419-26. PMID 2491665 DOI: 10.1007/Bf00015554  0.371
1989 Dean C, Favreau M, Bedbrook J, Dunsmuir P. Sequences 5' to translation start regulate expression of petunia rbcS genes. The Plant Cell. 1: 209-215. PMID 2535543 DOI: 10.1105/Tpc.1.2.209  0.369
1989 Dean C, Favreau M, Bond-Nutter D, Bedbrook J, Dunsmuir P. Sequences downstream of translation start regulate quantitative expression of two petunia rbcS genes. The Plant Cell. 1: 201-208. PMID 2535542 DOI: 10.1105/Tpc.1.2.201  0.365
1988 Dean C, Jones J, Favreau M, Dunsmuir P, Bedbrook J. Influence of flanking sequences on variability in expression levels of an introduced gene in transgenic tobacco plants Nucleic Acids Research. 16: 9267-9283. PMID 3174450 DOI: 10.1093/Nar/16.19.9267  0.37
1988 Dean C, Favreau M, Tamaki S, Bond-Nutter D, Dunsmuir P, Bedbrook J. Expression of tandem gene fusions in transgenic tobacco plants Nucleic Acids Research. 16: 7601-7618. PMID 3166132 DOI: 10.1093/Nar/16.15.7601  0.392
1988 Jones JDG, Dean C, Gidoni D, Gilbert D, Bond-Nutter D, Lee R, Bedbrook J, Dunsmuir P. Expression of bacterial chitinase protein in tobacco leaves using two photosynthetic gene promoters Molecular and General Genetics Mgg. 212: 536-542. DOI: 10.1007/Bf00330861  0.399
1987 Dean C, Favreau M, Dunsmuir P, Bedbrook J. Confirmation of the relative expression levels of the Petunia (Mitchell) rbcS genes Nucleic Acids Research. 15: 4655-4668. PMID 3588304 DOI: 10.1093/Nar/15.11.4655  0.385
1987 Vaeck M, Reynaerts A, Höfte H, Jansens S, De Beuckeleer M, Dean C, Zabeau M, Montagu MV, Leemans J. Transgenic plants protected from insect attack Nature. 328: 33-37. DOI: 10.1038/328033A0  0.369
1987 Dean C, van den Elzen P, Tamaki S, Black M, Dunsmuir P, Bedbrook J. Molecular characterization of the rbcS multi-gene family of Petunia (Mitchell) Molecular and General Genetics Mgg. 206: 465-474. DOI: 10.1007/Bf00428887  0.327
1986 Dean C, Tamaki S, Dunsmuir P, Favreau M, Katayama C, Dooner H, Bedbrook J. mRNA transcripts of several plant genes are polyadenylated at multiple sites in vivo Nucleic Acids Research. 14: 2229-2240. PMID 3960719 DOI: 10.1093/Nar/14.5.2229  0.36
1985 Dean C, Elzen Pvd, Tamaki S, Dunsmuir P, Bedbrook J. Linkage and homology analysis divides the eight genes for the small subunit of petunia ribulose 1,5-bisphosphate carboxylase into three gene families. Proceedings of the National Academy of Sciences of the United States of America. 82: 4964-4968. PMID 16593584 DOI: 10.1073/Pnas.82.15.4964  0.321
1985 Dean C, Elzen Pvd, Tamaki S, Dunsmuir P, Bedbrook J. Differential expression of the eight genes of the petunia ribulose bisphosphate carboxylase small subunit multi-gene family. The Embo Journal. 4: 3055-3061. DOI: 10.1002/J.1460-2075.1985.Tb04045.X  0.355
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