Adam Marcus - Publications

Emory University, Atlanta, GA 

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Zoeller EL, Pedro B, Konen J, Dwivedi B, Rupji M, Sundararaman N, Wang L, Horton JR, Zhong C, Barwick BG, Cheng X, Martinez ED, Torres MP, Kowalski J, Marcus AI, et al. Genetic heterogeneity within collective invasion packs drives leader and follower cell phenotypes. Journal of Cell Science. PMID 31515279 DOI: 10.1242/jcs.231514  0.32
2019 Owonikoko TK, Zhang G, Lallani SB, Chen Z, Martinson DE, Khuri FR, Lonial S, Marcus A, Sun SY. Evaluation of preclinical efficacy of everolimus and pasireotide in thyroid cancer cell lines and xenograft models. Plos One. 14: e0206309. PMID 30807575 DOI: 10.1371/journal.pone.0206309  0.52
2018 Haney S, Konen J, Marcus AI, Bazhenov M. The complex ecosystem in non small cell lung cancer invasion. Plos Computational Biology. 14: e1006131. PMID 29795571 DOI: 10.1371/journal.pcbi.1006131  0.32
2018 Hou Y, Konen J, Brat DJ, Marcus AI, Cooper LAD. TASI: A software tool for spatial-temporal quantification of tumor spheroid dynamics. Scientific Reports. 8: 7248. PMID 29739990 DOI: 10.1038/s41598-018-25337-4  0.32
2017 Richardson AM, Havel L, Koyen AE, Konen JM, Shupe JA, Wiles WG, Martin WD, Grossniklaus H, Sica GL, Gilbert-Ross M, Marcus A. Vimentin is required for lung adenocarcinoma metastasis via heterotypic tumor cell-cancer-associated fibroblast interactions during collective invasion. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29208669 DOI: 10.1158/1078-0432.CCR-17-1776  0.36
2017 Li Z, Ivanov AA, Su R, Gonzalez-Pecchi V, Qi Q, Liu S, Webber P, McMillan E, Rusnak L, Pham C, Chen X, Mo X, Revennaugh B, Zhou W, Marcus A, et al. Corrigendum: The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies. Nature Communications. 8: 15350. PMID 28416792 DOI: 10.1038/ncomms15350  0.52
2017 Li R, Ding C, Zhang J, Xie M, Park D, Ding Y, Chen G, Zhang G, Gilbert-Ross M, Zhou W, Marcus A, Sun SY, Chen ZG, Sica GL, Ramalingam SS, et al. Modulation of Bax and mTOR for cancer therapeutics. Cancer Research. PMID 28381544 DOI: 10.1158/0008-5472.CAN-16-2356  0.52
2017 Gilbert-Ross M, Konen J, Koo J, Shupe J, Robinson BS, Wiles WG, Huang C, Martin WD, Behera M, Smith GH, Hill CE, Rossi MR, Sica GL, Rupji M, Chen Z, ... ... Marcus AI, et al. Targeting adhesion signaling in KRAS, LKB1 mutant lung adenocarcinoma. Jci Insight. 2: e90487. PMID 28289710 DOI: 10.1172/jci.insight.90487  0.52
2017 Li Z, Ivanov AA, Su R, Gonzalez-Pecchi V, Qi Q, Liu S, Webber P, McMillan E, Rusnak L, Pham C, Chen X, Mo X, Revennaugh B, Zhou W, Marcus A, et al. The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies. Nature Communications. 8: 14356. PMID 28205554 DOI: 10.1038/ncomms14356  0.52
2017 Lee B, Konen J, Wilkinson S, Marcus AI, Jiang Y. Local alignment vectors reveal cancer cell-induced ECM fiber remodeling dynamics. Scientific Reports. 7: 39498. PMID 28045069 DOI: 10.1038/srep39498  0.32
2016 Okura H, Golbourn BJ, Shahzad U, Agnihotri S, Sabha N, Krieger JR, Figueiredo CA, Chalil A, Landon-Brace N, Riemenschneider A, Arai H, Smith CA, Xu S, Kaluz S, Marcus AI, et al. A role for activated Cdc42 in glioblastoma multiforme invasion. Oncotarget. PMID 27486972 DOI: 10.18632/oncotarget.10925  0.52
2016 Coke CJ, Scarlett KA, Chetram MA, Jones KJ, Sandifer BJ, Davis AS, Marcus AI, Hinton CV. Simultaneous Activation of Induced Heterodimerization between CXCR4 Chemokine Receptor and Cannabinoid Receptor 2 (CB2) Reveal a Mechanism for Regulation of Tumor Progression. The Journal of Biological Chemistry. PMID 26841863 DOI: 10.1074/jbc.M115.712661  0.52
2015 Liu F, Jin R, Liu X, Huang H, Wilkinson SC, Zhong D, Khuri FR, Fu H, Marcus A, He Y, Zhou W. LKB1 promotes cell survival by modulating TIF-IA-mediated pre-ribosomal RNA synthesis under uridine downregulated conditions. Oncotarget. PMID 26506235 DOI: 10.18632/oncotarget.6224  0.52
2015 Gilbert-Ross M, Marcus AI, Zhou W. RhoA, a novel tumor suppressor or oncogene as a therapeutic target? Genes & Diseases. 2: 2-3. PMID 26114154 DOI: 10.1016/j.gendis.2014.10.001  0.52
2015 Mao K, Liu F, Liu X, Khuri FR, Marcus AI, Li M, Zhou W. Re-expression of LKB1 in LKB1-mutant EKVX cells leads to resistance to paclitaxel through the up-regulation of MDR1 expression. Lung Cancer (Amsterdam, Netherlands). 88: 131-8. PMID 25769882 DOI: 10.1016/j.lungcan.2015.02.017  0.52
2014 Zhou W, Zhang J, Marcus AI. LKB1 Tumor Suppressor: Therapeutic Opportunities Knock when LKB1 Is Inactivated. Genes & Diseases. 1: 64-74. PMID 25679014 DOI: 10.1016/j.gendis.2014.06.002  0.52
2014 Brodie SA, Lombardo C, Li G, Kowalski J, Gandhi K, You S, Khuri FR, Marcus A, Vertino PM, Brandes JC. Aberrant promoter methylation of caveolin-1 is associated with favorable response to taxane-platinum combination chemotherapy in advanced NSCLC. Plos One. 9: e107124. PMID 25222296 DOI: 10.1371/journal.pone.0107124  0.52
2014 Yang L, Sajja HK, Cao Z, Qian W, Bender L, Marcus AI, Lipowska M, Wood WC, Andrew Wang Y. uPAR-targeted optical imaging contrasts as theranostic agents for tumor margin detection Theranostics. 4: 106-118. PMID 24396518 DOI: 10.7150/thno.7409  0.52
2014 Saba NF, Magliocca KR, Kim S, Muller S, Chen Z, Owonikoko TK, Sarlis NJ, Eggers C, Phelan V, Grist WJ, Chen AY, Ramalingam SS, Chen ZG, Beitler JJ, Shin DM, ... ... Marcus AI, et al. Acetylated tubulin (AT) as a prognostic marker in squamous cell carcinoma of the head and neck. Head and Neck Pathology. 8: 66-72. PMID 23881549 DOI: 10.1007/s12105-013-0476-6  0.52
2013 Yang Z, Garcia A, Xu S, Powell DR, Vertino PM, Singh S, Marcus AI. Withania somnifera root extract inhibits mammary cancer metastasis and epithelial to mesenchymal transition. Plos One. 8: e75069. PMID 24069380 DOI: 10.1371/journal.pone.0075069  0.52
2013 Marcus AI, Khuri FR. Energizing the search to target LKB1-mutant tumors. Cancer Discovery. 3: 843-5. PMID 23928772 DOI: 10.1158/2159-8290.CD-13-0296  0.52
2013 Zhou W, Marcus AI, Vertino PM. Dysregulation of mTOR activity through LKB1 inactivation. Chinese Journal of Cancer. 32: 427-33. PMID 23668926 DOI: 10.5732/cjc.013.10086  0.52
2013 Kline ER, Shupe J, Gilbert-Ross M, Zhou W, Marcus AI. LKB1 represses focal adhesion kinase (FAK) signaling via a FAK-LKB1 complex to regulate FAK site maturation and directional persistence. The Journal of Biological Chemistry. 288: 17663-74. PMID 23637231 DOI: 10.1074/jbc.M112.444620  0.52
2012 Kong KY, Marcus AI, Giannakakou P, Wang MD. Integrating image analysis algorithms in a web interface for the quantification of microtubule dynamics. International Journal of Computational Biology and Drug Design. 5: 298-313. PMID 23013655 DOI: 10.1504/IJCBDD.2012.049211  0.52
2012 Thaiparambil JT, Eggers CM, Marcus AI. AMPK regulates mitotic spindle orientation through phosphorylation of myosin regulatory light chain Molecular and Cellular Biology. 32: 3203-3217. PMID 22688514 DOI: 10.1128/MCB.00418-12  0.52
2012 Eggers CM, Kline ER, Zhong D, Zhou W, Marcus AI. STE20-related kinase adaptor protein α (STRADα) regulates cell polarity and invasion through PAK1 signaling in LKB1-null cells. The Journal of Biological Chemistry. 287: 18758-68. PMID 22493453 DOI: 10.1074/jbc.M111.316422  0.52
2012 Olivera A, Moore TW, Hu F, Brown AP, Sun A, Liotta DC, Snyder JP, Yoon Y, Shim H, Marcus AI, Miller AH, Pace TW. Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties. International Immunopharmacology. 12: 368-77. PMID 22197802 DOI: 10.1016/j.intimp.2011.12.009  0.52
2012 Khoury HJ, Garcia-Manero G, Borthakur G, Kadia T, Foudray MC, Arellano M, Langston A, Bethelmie-Bryan B, Rush S, Litwiler K, Karan S, Simmons H, Marcus AI, Ptaszynski M, Kantarjian H. A phase 1 dose-escalation study of ARRY-520, a kinesin spindle protein inhibitor, in patients with advanced myeloid leukemias. Cancer. 118: 3556-64. PMID 22139909 DOI: 10.1002/cncr.26664  0.52
2011 Kline ER, Muller S, Pan L, Tighiouart M, Chen ZG, Marcus AI. Localization-specific LKB1 loss in head and neck squamous cell carcinoma metastasis. Head & Neck. 33: 1501-12. PMID 21928424 DOI: 10.1002/hed.21638  0.52
2011 Thaiparambil JT, Bender L, Ganesh T, Kline E, Patel P, Liu Y, Tighiouart M, Vertino PM, Harvey RD, Garcia A, Marcus AI. Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation. International Journal of Cancer. Journal International Du Cancer. 129: 2744-55. PMID 21538350 DOI: 10.1002/ijc.25938  0.52
2011 Kauh J, Chanel-Vos C, Escuin D, Fanucchi MP, Harvey RD, Saba N, Shin DM, Gal A, Pan L, Kutner M, Ramalingam SS, Bender L, Marcus A, Giannakakou P, Khuri FR. Farnesyl transferase expression determines clinical response to the docetaxel-lonafarnib combination in patients with advanced malignancies. Cancer. 117: 4049-59. PMID 21365629 DOI: 10.1002/cncr.26004  0.52
2010 Marcus AI, Zhou W. LKB1 regulated pathways in lung cancer invasion and metastasis Journal of Thoracic Oncology. 5: 1883-1886. PMID 21102257 DOI: 10.1097/JTO.0b013e3181fbc28a  0.52
2010 Malavé MO, Zhao X, Kong KY, Marcus AI, Wang MD. Automatic tip selection for microtubule dynamics quantification. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2010: 3142-5. PMID 21096591 DOI: 10.1109/IEMBS.2010.5627190  0.52
2010 David E, Kaufman JL, Flowers CR, Schafer-Hales K, Torre C, Chen J, Marcus AI, Sun SY, Boise LH, Lonial S. Tipifarnib sensitizes cells to proteasome inhibition by blocking degradation of bortezomib-induced aggresomes. Blood. 116: 5285-8. PMID 20844234 DOI: 10.1182/blood-2010-03-272393  0.52
2010 Kang S, Elf S, Lythgoe K, Hitosugi T, Taunton J, Zhou W, Xiong L, Wang D, Muller S, Fan S, Sun SY, Marcus AI, Gu TL, Polakiewicz RD, Chen ZG, et al. p90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells. The Journal of Clinical Investigation. 120: 1165-77. PMID 20234090 DOI: 10.1172/JCI40582  0.52
2009 Morales AR, Yanez CO, Schafer-Hales KJ, Marcus AI, Belfield KD. Biomolecule labeling and imaging with a new fluorenyl two-photon fluorescent probe. Bioconjugate Chemistry. 20: 1992-2000. PMID 19799436 DOI: 10.1021/bc900302t  0.52
2009 Morales AR, Schafer-Hales KJ, Yanez CO, Bondar MV, Przhonska OV, Marcus AI, Belfield KD. Excited state intramolecular proton transfer and photophysics of a new fluorenyl two-photon fluorescent probe. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 10: 2073-81. PMID 19449363 DOI: 10.1002/cphc.200900032  0.52
2009 Schmack I, Berglin L, Nie X, Wen J, Kang SJ, Marcus AI, Yang H, Lynn MJ, Kapp JA, Grossniklaus HE. Modulation of choroidal neovascularization by subretinal injection of retinal pigment epithelium and polystyrene microbeads Molecular Vision. 15: 146-161. PMID 19158960  0.52
2008 Morales AR, Schafer-Hales KJ, Marcus AI, Belfield KD. Amine-reactive fluorene probes: synthesis, optical characterization, bioconjugation, and two-photon fluorescence imaging. Bioconjugate Chemistry. 19: 2559-67. PMID 19090700 DOI: 10.1021/bc800415t  0.52
2008 Zhong D, Liu X, Schafer-Hales K, Marcus AI, Khuri FR, Sun SY, Zhou W. 2-Deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMP-activated protein kinase signaling activation or glycolysis inhibition. Molecular Cancer Therapeutics. 7: 809-17. PMID 18413794 DOI: 10.1158/1535-7163.MCT-07-0559  0.52
2008 Zhang S, Schafer-Hales K, Khuri FR, Zhou W, Vertino PM, Marcus AI. The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity. Cancer Research. 68: 740-8. PMID 18245474 DOI: 10.1158/0008-5472.CAN-07-2989  0.52
2007 Marcus AI. Visualization of spindle behavior using confocal microscopy Methods in Molecular Medicine. 137: 125-137. PMID 18085226  0.52
2007 Ruan G, Agrawal A, Marcus AI, Nie S. Imaging and tracking of tat peptide-conjugated quantum dots in living cells: new insights into nanoparticle uptake, intracellular transport, and vesicle shedding. Journal of the American Chemical Society. 129: 14759-66. PMID 17983227 DOI: 10.1021/ja074936k  0.52
2007 Sun SY, Liu X, Zou W, Yue P, Marcus AI, Khuri FR. The farnesyltransferase inhibitor lonafarnib induces CCAAT/enhancer-binding protein homologous protein-dependent expression of death receptor 5, leading to induction of apoptosis in human cancer cells. The Journal of Biological Chemistry. 282: 18800-9. PMID 17493934 DOI: 10.1074/jbc.M611438200  0.52
2007 Schafer-Hales K, Iaconelli J, Snyder JP, Prussia A, Nettles JH, El-Naggar A, Khuri FR, Giannakakou P, Marcus AI. Farnesyl transferase inhibitors impair chromosomal maintenance in cell lines and human tumors by compromising CENP-E and CENP-F function. Molecular Cancer Therapeutics. 6: 1317-28. PMID 17431110 DOI: 10.1158/1535-7163.MCT-06-0703  0.52
2007 Luhn P, Wang H, Marcus AI, Fu H. Identification of FAKTS as a novel 14-3-3-associated nuclear protein. Proteins. 67: 479-89. PMID 17256767 DOI: 10.1002/prot.21288  0.52
2006 Kong KY, Marcus AI, Hong JY, Giannakakou P, Wang MD. Automatic microtubule tracking for QD-based in vivo cell imaging and drug efficacy study. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 1: 3321-4. PMID 17947021 DOI: 10.1109/IEMBS.2006.259750  0.52
2006 Marcus AI, O'Brate AM, Buey RM, Zhou J, Thomas S, Khuri FR, Andreu JM, Díaz F, Giannakakou P. Farnesyltransferase inhibitors reverse taxane resistance. Cancer Research. 66: 8838-46. PMID 16951201 DOI: 10.1158/0008-5472.CAN-06-0699  0.52
2006 Zhou C, Cunningham L, Marcus AI, Li Y, Kahn RA. Arl2 and Arl3 regulate different microtubule-dependent processes. Molecular Biology of the Cell. 17: 2476-87. PMID 16525022 DOI: 10.1091/mbc.E05-10-0929  0.52
2005 Edler MC, Buey RM, Gussio R, Marcus AI, Vanderwal CD, Sorensen EJ, Díaz JF, Giannakakou P, Hamel E. Cyclostreptin (FR182877), an antitumor tubulin-polymerizing agent deficient in enhancing tubulin assembly despite its high affinity for the taxoid site. Biochemistry. 44: 11525-38. PMID 16114889 DOI: 10.1021/bi050660m  0.52
2005 Marcus AI, Zhou J, O'Brate A, Hamel E, Wong J, Nivens M, El-Naggar A, Yao TP, Khuri FR, Giannakakou P. The synergistic combination of the farnesyl transferase inhibitor lonafarnib and paclitaxel enhances tubulin acetylation and requires a functional tubulin deacetylase. Cancer Research. 65: 3883-93. PMID 15867388 DOI: 10.1158/0008-5472.CAN-04-3757  0.52
2005 Ambrose JC, Li W, Marcus A, Ma H, Cyr R. A minus-end-directed kinesin with plus-end tracking protein activity is involved in spindle morphogenesis. Molecular Biology of the Cell. 16: 1584-92. PMID 15659646 DOI: 10.1091/mbc.E04-10-0935  0.52
2005 Marcus AI, Peters U, Thomas SL, Garrett S, Zelnak A, Kapoor TM, Giannakakou P. Mitotic kinesin inhibitors induce mitotic arrest and cell death in Taxol-resistant and -sensitive cancer cells. The Journal of Biological Chemistry. 280: 11569-77. PMID 15653676 DOI: 10.1074/jbc.M413471200  0.52
2002 Marcus AI, Ambrose JC, Blickley L, Hancock WO, Cyr RJ. Arabidopsis thaliana protein, ATK1, is a minus-end directed kinesin that exhibits non-processive movement. Cell Motility and the Cytoskeleton. 52: 144-50. PMID 12112142 DOI: 10.1002/cm.10045  0.52
2002 Chen C, Marcus A, Li W, Hu Y, Calzada JP, Grossniklaus U, Cyr RJ, Ma H. The Arabidopsis ATK1 gene is required for spindle morphogenesis in male meiosis. Development (Cambridge, England). 129: 2401-9. PMID 11973272  0.52
Show low-probability matches.