James C. Iatridis, PhD - Publications

Affiliations: 
1990-1996 Biomedical Engineering Columbia University, New York, NY 
 1996-2010 Orthopaedics The University of Vermont and State Agricultural College 
 2010- Orthopaedics Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
Biomechanics

167 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Stinnett-Donnelly JM, MacLean JJ, Iatridis JC. A Removable Precision Device for In-Vivo Mechanical Compression of Rat Tail Intervertebral Discs. Journal of Medical Devices. 1: 56-61. PMID 38529339 DOI: 10.1115/1.2355692  0.73
2024 Stinnett-Donnelly JM, MacLean JJ, Iatridis JC. A Removable Precision Device for In-Vivo Mechanical Compression of Rat Tail Intervertebral Discs. Journal of Medical Devices. 1: 56-61. PMID 38529339 DOI: 10.1115/1.2355692  0.73
2024 Lai A, Iliff D, Zaheer K, Gansau J, Laudier DM, Zachariou V, Iatridis JC. Annulus Fibrosus Injury Induces Acute Neuroinflammation and Chronic Glial Response in Dorsal Root Ganglion and Spinal Cord-An In Vivo Rat Discogenic Pain Model. International Journal of Molecular Sciences. 25. PMID 38339040 DOI: 10.3390/ijms25031762  0.715
2023 Panebianco CJ, Constant C, Vernengo AJ, Nehrbass D, Gehweiler D, DiStefano TJ, Martin J, Alpert DJ, Chaudhary SB, Hecht AC, Seifert AC, Nicoll SB, Grad S, Zeiter S, Iatridis JC. Combining adhesive and nonadhesive injectable hydrogels for intervertebral disc repair in an ovine discectomy model. Jor Spine. 6: e1293. PMID 38156055 DOI: 10.1002/jsp2.1293  0.802
2023 Wang D, Lai A, Gansau J, Seifert AC, Munitz J, Zaheer K, Bhadouria N, Lee Y, Nasser P, Laudier DM, Holguin N, Hecht AC, Iatridis JC. Lumbar endplate microfracture injury induces Modic-like changes, intervertebral disc degeneration and spinal cord sensitization - An In Vivo Rat Model. The Spine Journal : Official Journal of the North American Spine Society. PMID 37086976 DOI: 10.1016/j.spinee.2023.04.012  0.721
2023 Basatvat S, Bach FC, Barcellona MN, Binch AL, Buckley CT, Bueno B, Chahine NO, Chee A, Creemers LB, Dudli S, Fearing B, Ferguson SJ, Gansau J, Gantenbein B, Gawri R, ... ... Iatridis JC, et al. Harmonization and standardization of nucleus pulposus cell extraction and culture methods. Jor Spine. 6: e1238. PMID 36994456 DOI: 10.1002/jsp2.1238  0.786
2023 Lai A, Iliff D, Zaheer K, Wang D, Gansau J, Laudier DM, Zachariou V, Iatridis JC. Spinal Cord Sensitization and Spinal Inflammation from an In Vivo Rat Endplate Injury Associated with Painful Intervertebral Disc Degeneration. International Journal of Molecular Sciences. 24. PMID 36834838 DOI: 10.3390/ijms24043425  0.697
2023 Wang D, Lai A, Gansau J, Seifert AC, Munitz J, Zaheer K, Bhadouria N, Lee Y, Nasser P, Laudier DM, Holguin N, Hecht AC, Iatridis JC. Lumbar endplate microfracture injury induces Modic-like changes, intervertebral disc degeneration and spinal cord sensitization - An In Vivo Rat Model. Biorxiv : the Preprint Server For Biology. PMID 36778423 DOI: 10.1101/2023.01.27.525924  0.719
2022 DiStefano TJ, Vaso K, Panebianco CJ, Danias G, Chionuma HN, Kunnath K, Karoulias SZ, Wang M, Xu P, Davé RN, Sahoo S, Weiser JR, Iatridis JC. Hydrogel-Embedded Poly(Lactic--Glycolic Acid) Microspheres for the Delivery of hMSC-Derived Exosomes to Promote Bioactive Annulus Fibrosus Repair. Cartilage. 13: 19476035221113959. PMID 36040157 DOI: 10.1177/19476035221113959  0.793
2022 Zehra U, Tryfonidou M, Iatridis JC, Illien-Jünger S, Mwale F, Samartzis D. Mechanisms and clinical implications of intervertebral disc calcification. Nature Reviews. Rheumatology. 18: 352-362. PMID 35534553 DOI: 10.1038/s41584-022-00783-7  0.723
2022 Wang D, Lai A, Gansau J, Nasser P, Lee Y, Laudier DM, Iatridis JC. Ex vivo biomechanical evaluation of Acute lumbar endplate injury and comparison to annulus fibrosus injury in a rat model. Journal of the Mechanical Behavior of Biomedical Materials. 131: 105234. PMID 35462160 DOI: 10.1016/j.jmbbm.2022.105234  0.702
2021 D'Erminio DN, Krishnamoorthy D, Lai A, Hoy RC, Natelson DM, Poeran J, Torres A, Laudier DM, Nasser P, Vashishth D, Illien-Jünger S, Iatridis JC. High fat diet causes inferior vertebral structure and function without disc degeneration in RAGE-KO mice. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 34676612 DOI: 10.1002/jor.25191  0.779
2021 Di Pauli von Treuheim T, Torre OM, Ferreri ED, Nasser P, Abbondandolo A, Delgado Caceres M, Lin D, Docheva D, Iatridis JC. and Are Both Required to Maintain Biomechanical Function and Prevent Intervertebral Disc Degeneration. Cartilage. 19476035211029696. PMID 34486420 DOI: 10.1177/19476035211029696  0.736
2021 Dahia CL, Engiles JB, Gullbrand SE, Iatridis JC, Lai A, Le Maitre CL, Lotz JC, Masuda K, Séguin CA, Tryfonidou MA. A perspective on the initiative to develop a multi-species histopathology series. Jor Spine. 4: e1165. PMID 34337339 DOI: 10.1002/jsp2.1165  0.653
2021 Lai A, Gansau J, Gullbrand SE, Crowley J, Cunha C, Dudli S, Engiles JB, Fusellier M, Goncalves RM, Nakashima D, Okewunmi J, Pelletier M, Presciutti SM, Schol J, Takeoka Y, ... ... Iatridis JC, et al. Development of a standardized histopathology scoring system for intervertebral disc degeneration in rat models: An initiative of the ORS spine section. Jor Spine. 4: e1150. PMID 34337335 DOI: 10.1002/jsp2.1150  0.695
2021 Gullbrand SE, Ashinsky BG, Lai A, Gansau J, Crowley J, Cunha C, Engiles JB, Fusellier M, Muehleman C, Pelletier M, Presciutti S, Schol J, Takeoka Y, Yurube T, Zhang Y, ... ... Iatridis JC, et al. Development of a standardized histopathology scoring system for intervertebral disc degeneration and regeneration in rabbit models-An initiative of the ORSspine section. Jor Spine. 4: e1147. PMID 34337334 DOI: 10.1002/jsp2.1147  0.704
2021 DiStefano TJ, Vaso K, Danias G, Chionuma HN, Weiser JR, Iatridis JC. Extracellular Vesicles as an Emerging Treatment Option for Intervertebral Disc Degeneration: Therapeutic Potential, Translational Pathways, and Regulatory Considerations. Advanced Healthcare Materials. e2100596. PMID 34297485 DOI: 10.1002/adhm.202100596  0.788
2020 Zeldin L, Mosley GE, Laudier D, Gallate ZS, Gansau J, Hoy RC, Poeran J, Iatridis JC. Spatial mapping of collagen content and structure in human intervertebral disk degeneration. Jor Spine. 3: e1129. PMID 33392461 DOI: 10.1002/jsp2.1129  0.706
2020 Hoy RC, D'Erminio DN, Krishnamoorthy D, Natelson DM, Laudier DM, Illien-Jünger S, Iatridis JC. Advanced glycation end products cause RAGE-dependent annulus fibrosus collagen disruption and loss identified using in situ second harmonic generation imaging in mice intervertebral disk in vivo and in organ culture models. Jor Spine. 3: e1126. PMID 33392460 DOI: 10.1002/jsp2.1126  0.708
2020 DiStefano TJ, Shmukler JO, Danias G, Iatridis JC. The Functional Role of Interface Tissue Engineering in Annulus Fibrosus Repair: Bridging Mechanisms of Hydrogel Integration with Regenerative Outcomes. Acs Biomaterials Science & Engineering. 6: 6556-6586. PMID 33320618 DOI: 10.1021/acsbiomaterials.0c01320  0.802
2020 Fujii K, Lai A, Korda N, Hom WW, Evashwick-Rogler TW, Nasser P, Hecht AC, Iatridis JC. Ex-vivo biomechanics of repaired rat intervertebral discs using genipin crosslinked fibrin adhesive hydrogel. Journal of Biomechanics. 113: 110100. PMID 33142205 DOI: 10.1016/j.jbiomech.2020.110100  0.812
2020 Mosley GE, Wang M, Nasser P, Lai A, Charen DA, Zhang B, Iatridis JC. Males and females exhibit distinct relationships between intervertebral disc degeneration and pain in a rat model. Scientific Reports. 10: 15120. PMID 32934258 DOI: 10.1038/S41598-020-72081-9  0.789
2020 DiStefano TJ, Shmukler JO, Danias G, Di Pauli von Treuheim T, Hom WW, Goldberg DA, Laudier DM, Nasser PR, Hecht AC, Nicoll SB, Iatridis JC. Development of a two-part biomaterial adhesive strategy for annulus fibrosus repair and ex vivo evaluation of implant herniation risk. Biomaterials. 258: 120309. PMID 32823020 DOI: 10.1016/J.Biomaterials.2020.120309  0.807
2020 Di Pauli von Treuheim T, Torre OM, Mosley GE, Nasser P, Iatridis JC. Measuring the neutral zone of spinal motion segments: Comparison of multiple analysis methods to quantify spinal instability. Jor Spine. 3: e1088. PMID 32613163 DOI: 10.1002/jsp2.1088  0.775
2020 Panebianco CJ, DiStefano TJ, Mui B, Hom WW, Iatridis JC. Crosslinker concentration controls TGFβ-3 release and annulus fibrosus cell apoptosis in genipin-crosslinked fibrin hydrogels. European Cells & Materials. 39: 211-226. PMID 32396210 DOI: 10.22203/Ecm.V039A14  0.803
2020 Natelson DM, Lai A, Krishnamoorthy D, Hoy RC, Iatridis JC, Illien-Jünger S. Leptin signaling and the intervertebral disc: Sex dependent effects of leptin receptor deficiency and Western diet on the spine in a type 2 diabetes mouse model. Plos One. 15: e0227527. PMID 32374776 DOI: 10.1371/Journal.Pone.0227527  0.766
2020 Long RG, Ferguson SJ, Benneker LM, Sakai D, Li Z, Pandit A, Grijpma DW, Eglin D, Zeiter S, Schmid T, Eberli U, Nehrbass D, Di Pauli von Treuheim T, Alini M, Iatridis JC, et al. Morphological and biomechanical effects of annulus fibrosus injury and repair in an ovine cervical model. Jor Spine. 3: e1074. PMID 32211587 DOI: 10.1002/jsp2.1074  0.619
2020 Lin D, Alberton P, Delgado Caceres M, Prein C, Clausen-Schaumann H, Dong J, Aszodi A, Shukunami C, Iatridis JC, Docheva D. Loss of tenomodulin expression is a risk factor for age-related intervertebral disc degeneration. Aging Cell. e13091. PMID 32083813 DOI: 10.1111/Acel.13091  0.34
2019 Torre OM, Mroz V, Benitez ARM, Huang AH, Iatridis JC. Neonatal annulus fibrosus regeneration occurs via recruitment and proliferation of Scleraxis-lineage cells. Npj Regenerative Medicine. 4: 23. PMID 33339825 DOI: 10.1038/s41536-019-0085-4  0.805
2019 Torre OM, Mroz V, Benitez ARM, Huang AH, Iatridis JC. Neonatal annulus fibrosus regeneration occurs via recruitment and proliferation of -lineage cells. Npj Regenerative Medicine. 4: 23. PMID 31885875 DOI: 10.1038/S41536-019-0085-4  0.806
2019 DiStefano TJ, Illien-Jünger S, Iatridis JC. Homeostasis disrupted by strain mechanosensing. Nature Biomedical Engineering. 3: 951-952. PMID 31811265 DOI: 10.1038/S41551-019-0491-3  0.782
2019 Lai A, Ho L, Evashwick-Rogler TW, Watanabe H, Salandra J, Winkelstein BA, Laudier D, Hecht AC, Pasinetti GM, Iatridis JC. Correction: Dietary polyphenols as a safe and novel intervention for modulating pain associated with intervertebral disc degeneration in an in-vivo rat model. Plos One. 14: e0225674. PMID 31747423 DOI: 10.1371/journal.pone.0225674  0.781
2019 Zhang C, Smith MP, Zhou GK, Lai A, Hoy RC, Mroz V, Torre OM, Laudier DM, Bradley EW, Westendorf JJ, Iatridis JC, Illien-Jünger S. Phlpp1 is associated with human intervertebral disc degeneration and its deficiency promotes healing after needle puncture injury in mice. Cell Death & Disease. 10: 754. PMID 31582730 DOI: 10.1038/S41419-019-1985-3  0.792
2019 Lai A, Ho L, Evashwick-Rogler TW, Watanabe H, Salandra J, Winkelstein BA, Laudier D, Hecht AC, Pasinetti GM, Iatridis JC. Dietary polyphenols as a safe and novel intervention for modulating pain associated with intervertebral disc degeneration in an in-vivo rat model. Plos One. 14: e0223435. PMID 31577822 DOI: 10.1371/Journal.Pone.0223435  0.805
2019 Hom WW, Tschopp M, Lin HA, Nasser P, Laudier DM, Hecht AC, Nicoll SB, Iatridis JC. Composite biomaterial repair strategy to restore biomechanical function and reduce herniation risk in an ex vivo large animal model of intervertebral disc herniation with varying injury severity. Plos One. 14: e0217357. PMID 31136604 DOI: 10.1371/Journal.Pone.0217357  0.375
2019 Lin HA, Varma DM, Hom WW, Cruz MA, Nasser PR, Phelps RG, Iatridis JC, Nicoll SB. Injectable cellulose-based hydrogels as nucleus pulposus replacements: Assessment of in vitro structural stability, ex vivo herniation risk, and in vivo biocompatibility. Journal of the Mechanical Behavior of Biomedical Materials. 96: 204-213. PMID 31054515 DOI: 10.1016/J.Jmbbm.2019.04.021  0.377
2019 Mosley GE, Hoy RC, Nasser P, Kaseta T, Lai A, Evashwick-Rogler TW, Lee M, Iatridis JC. Sex Differences in Rat Intervertebral Disc Structure and Function Following Annular Puncture Injury. Spine. PMID 30973506 DOI: 10.1097/Brs.0000000000003055  0.778
2019 Torre OM, Evashwick-Rogler TW, Nasser P, Iatridis JC. Biomechanical test protocols to detect minor injury effects in intervertebral discs. Journal of the Mechanical Behavior of Biomedical Materials. 95: 13-20. PMID 30947120 DOI: 10.1016/J.Jmbbm.2019.03.024  0.792
2019 Gupta N, Cruz MA, Nasser P, Rosenberg JD, Iatridis JC. Fibrin-Genipin Hydrogel for Cartilage Tissue Engineering in Nasal Reconstruction. The Annals of Otology, Rhinology, and Laryngology. 3489419836667. PMID 30862177 DOI: 10.1177/0003489419836667  0.304
2018 Buckley CT, Hoyland JA, Fujii K, Pandit A, Iatridis JC, Grad S. Critical aspects and challenges for intervertebral disc repair and regeneration-Harnessing advances in tissue engineering. Jor Spine. 1: e1029. PMID 30895276 DOI: 10.1002/jsp2.1029  0.6
2018 Torre OM, Mroz V, Bartelstein MK, Huang AH, Iatridis JC. Annulus fibrosus cell phenotypes in homeostasis and injury: implications for regenerative strategies. Annals of the New York Academy of Sciences. PMID 30604562 DOI: 10.1111/Nyas.13964  0.803
2018 Krishnamoorthy D, Hoy RC, Natelson DM, Torre OM, Laudier DM, Iatridis JC, Illien-Jünger S. Dietary advanced glycation end-product consumption leads to mechanical stiffening of murine intervertebral discs. Disease Models & Mechanisms. PMID 30498097 DOI: 10.1242/Dmm.036012  0.787
2018 Evashwick-Rogler TW, Lai A, Watanabe H, Salandra JM, Winkelstein BA, Cho SK, Hecht AC, Iatridis JC. Inhibiting tumor necrosis factor-alpha at time of induced intervertebral disc injury limits long-term pain and degeneration in a rat model. Jor Spine. 1. PMID 29963655 DOI: 10.1002/jsp2.1014  0.786
2018 Long RG, Zderic I, Gueorguiev B, Ferguson SJ, Alini M, Grad S, Iatridis JC. Effects of Level, Loading Rate, Injury and Repair on Biomechanical Response of Ovine Cervical Intervertebral Discs. Annals of Biomedical Engineering. PMID 29926304 DOI: 10.1007/S10439-018-2077-8  0.624
2018 Varma DM, Lin HA, Long RG, Gold GT, Hecht AC, Iatridis JC, Nicoll SB. Thermoresponsive, redox-polymerized cellulosic hydrogels undergo in situ gelation and restore intervertebral disc biomechanics post discectomy. European Cells & Materials. 35: 300-317. PMID 29845998 DOI: 10.22203/Ecm.V035A21  0.653
2018 Martin JT, Gullbrand SE, Fields AJ, Purmessur D, Diwan AD, Oxland TR, Chiba K, Guilak F, Hoyland JA, Iatridis JC. Publication trends in spine research from 2007 to 2016: Comparison of the Orthopaedic Research Society Spine Section and the International Society for the Study of the Lumbar Spine. Jor Spine. 1: e1006. PMID 29770804 DOI: 10.1002/jsp2.1006  0.753
2018 Zhou Z, Zeiter S, Schmid T, Sakai D, Iatridis JC, Zhou G, Richards RG, Alini M, Grad S, Li Z. Effect of the CCL5-Releasing Fibrin Gel for Intervertebral Disc Regeneration. Cartilage. 1947603518764263. PMID 29582673 DOI: 10.1177/1947603518764263  0.389
2018 Torre OM, Das R, Berenblum RE, Huang AH, Iatridis JC. Neonatal mouse intervertebral discs heal with restored function following herniation injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701492R. PMID 29570392 DOI: 10.1096/Fj.201701492R  0.799
2017 Cruz MA, Hom WW, Tyler D, Merrill R, Torre OM, Lin HA, Hecht A, Illien-Junger S, Iatridis JC. Cell-Seeded Adhesive Biomaterial for Repair of Annulus Fibrosus Defects in Intervertebral Discs. Tissue Engineering. Part A. PMID 29214889 DOI: 10.1089/ten.TEA.2017.0334  0.803
2017 Illien-Jünger S, Palacio-Mancheno P, Kindschuh WF, Chen X, Sroga GE, Vashishth D, Iatridis JC. Dietary Advanced Glycation End Products have Sex-and Age Dependent Effects on Vertebral Bone Microstructure and Mechanical Function in Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 29160901 DOI: 10.1002/Jbmr.3321  0.703
2017 Nakazawa KR, Walter BA, Laudier DM, Krishnamoorthy D, Mosley GE, Spiller KL, Iatridis JC. Accumulation and localization of macrophage phenotypes with human intervertebral disc degeneration. The Spine Journal : Official Journal of the North American Spine Society. PMID 29031872 DOI: 10.1016/J.Spinee.2017.09.018  0.791
2017 Shi C, Qiu S, Riester SM, Das V, Zhu B, Wallace AA, van Wijnen AJ, Mwale F, Iatridis JC, Sakai D, Votta-Velis G, Yuan W, Im HJ. Animal models for studying the etiology and treatment of low back pain. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 28921656 DOI: 10.1002/Jor.23741  0.32
2017 Palacio-Mancheno PE, Evashwick-Rogler TW, Laudier DM, Purmessur D, Iatridis JC. Hyperosmolarity Induces Notochordal Cell Differentiation with Aquaporin3 Upregulation and Reduced N-cadherin Expression. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 28853179 DOI: 10.1002/Jor.23715  0.797
2017 Mosley GE, Evashwick-Rogler TW, Lai A, Iatridis JC. Looking beyond the intervertebral disc: the need for behavioral assays in models of discogenic pain. Annals of the New York Academy of Sciences. PMID 28797134 DOI: 10.1111/Nyas.13429  0.784
2017 Cruz MA, McAnany S, Gupta N, Long R, Nasser PR, Eglin D, Hecht A, Illien-Junger S, Iatridis JC. Structural and Chemical Modification to Improve Adhesive and Material Properties of Fibrin-Genipin for Repair of Annulus Fibrosus Defects in Intervertebral Discs. Journal of Biomechanical Engineering. PMID 28464119 DOI: 10.1115/1.4036623  0.792
2017 Dowdell J, Erwin M, Choma T, Vaccaro A, Iatridis J, Cho SK. Intervertebral Disk Degeneration and Repair. Neurosurgery. 80: S46-S54. PMID 28350945 DOI: 10.1093/Neuros/Nyw078  0.37
2016 Long RG, Rotman SG, Hom WW, Assael DJ, Grijpma DW, Iatridis JC. In vitro and biomechanical screening of polyethylene glycol and poly(trimethylene carbonate) block copolymers for annulus fibrosus repair. Journal of Tissue Engineering and Regenerative Medicine. PMID 27860368 DOI: 10.1002/Term.2356  0.652
2016 Illien-Jünger S, Torre OM, Kindschuh WF, Chen X, Laudier DM, Iatridis JC. Intervertebral disc degeneration, ectopic calcification, advanced glycation end products, nucleus pulposus cells. European Cells & Materials. 32: 257-270. PMID 27858401 DOI: 10.22203/eCM.v032a17  0.734
2016 Iatridis JC, Kang J, Kandel R, Risbud MV. New Horizons in Spine Research: Disc biology, spine biomechanics and pathomechanisms of back pain. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 34: 1287-1288. PMID 27571441 DOI: 10.1002/Jor.23375  0.314
2016 Walter BA, Purmessur D, Moon A, Occhiogrosso J, Laudier DM, Hecht AC, Iatridis JC. Reduced tissue osmolarity increases TRPV4 expression and pro-inflammatory cytokines in intervertebral disc cells. European Cells & Materials. 32: 123-36. PMID 27434269 DOI: 10.22203/Ecm.V032A08  0.789
2016 Likhitpanichkul M, Torre OM, Gruen J, Walter BA, Hecht AC, Iatridis JC. Do mechanical strain and TNF-α interact to amplify pro-inflammatory cytokine production in human annulus fibrosus cells? Journal of Biomechanics. 49: 1214-20. PMID 26924657 DOI: 10.1016/J.Jbiomech.2016.02.029  0.768
2016 Vo NV, Hartman RA, Patil PR, Risbud MV, Kletsas D, Iatridis JC, Hoyland JA, Le Maitre CL, Sowa GA, Kang JD. Molecular mechanisms of biological aging in intervertebral discs. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 26890203 DOI: 10.1002/Jor.23195  0.598
2016 Long RG, Torre OM, Hom WW, Assael DJ, Iatridis JC. Design Requirements for Annulus Fibrosus Repair: Review of Forces, Displacements, and Material Properties of the Intervertebral Disk and a Summary of Candidate Hydrogels for Repair. Journal of Biomechanical Engineering. 138: 021007. PMID 26720265 DOI: 10.1115/1.4032353  0.805
2016 Kindschuh WF, Palacio-Mancheno P, Chen X, Iatridis JC, Illien-Junger S. Effects of Long-Term Exposure of Exogenous Advanced Glycation Endproducts on Vertebral Bone Microarchitecture; Sex-Differences on Structure Derived Mechanical Properties Global Spine Journal. 6: s-0036-1582655-s-003. DOI: 10.1055/S-0036-1582655  0.689
2016 Long R, Rotman S, Hom W, Assael D, Illien-Junger S, Grijpma D, Iatridis JC. Polyethylene Glycol and Poly (Trimethylene Carbonate) Block Copolymers for Annulus Fibrosus Repair have High Cytocompatibility, Restore Axial Range of Motion and have Some Herniation Risk Global Spine Journal. 6: s-0036-1582589-s-003. DOI: 10.1055/S-0036-1582589  0.801
2016 Likhitpanichkul M, Torre OM, Gruen J, Walter BA, Hecht AC, Iatridis JC. Do mechanical strain and TNF-α interact to amplify pro-inflammatory cytokine production in human annulus fibrosus cells? Journal of Biomechanics. DOI: 10.1016/j.jbiomech.2016.02.029  0.767
2015 Lai A, Moon A, Purmessur D, Skovrlj B, Laudier DM, Winkelstein BA, Cho SK, Hecht AC, Iatridis JC. Annular puncture with tumor necrosis factor-alpha injection enhances painful behavior with disc degeneration in-vivo. The Spine Journal : Official Journal of the North American Spine Society. PMID 26610672 DOI: 10.1016/J.Spinee.2015.11.019  0.793
2015 Long RG, Bürki A, Zysset P, Eglin D, Grijpma DW, Blanquer SB, Hecht AC, Iatridis JC. Mechanical Restoration and Failure Analyses of a Hydrogel and Scaffold Composite Strategy for Annulus Fibrosus Repair. Acta Biomaterialia. PMID 26577987 DOI: 10.1016/J.Actbio.2015.11.015  0.641
2015 Illien-Jünger S, Sedaghatpour DD, Laudier DM, Hecht AC, Qureshi SA, Iatridis JC. Development of a bovine decellularized extracellular matrix-biomaterial for nucleus pulposus regeneration. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. PMID 26509556 DOI: 10.1002/Jor.23088  0.74
2015 Likhitpanichkul M, Kim Y, Torre OM, See E, Kazezian Z, Pandit A, Hecht AC, Iatridis JC. Fibrin-genipin annulus fibrosus sealant as a delivery system for anti-TNFα drug. The Spine Journal : Official Journal of the North American Spine Society. PMID 25912501 DOI: 10.1016/J.Spinee.2015.04.026  0.776
2015 Walter BA, Purmessur D, Likhitpanichkul M, Weinberg A, Cho SK, Qureshi SA, Hecht AC, Iatridis JC. Inflammatory Kinetics and Efficacy of Anti-inflammatory Treatments on Human Nucleus Pulposus Cells. Spine. PMID 25893355 DOI: 10.1097/Brs.0000000000000932  0.775
2015 Gantenbein B, Illien-Jünger S, Chan SC, Walser J, Haglund L, Ferguson SJ, Iatridis JC, Grad S. Organ culture bioreactors--platforms to study human intervertebral disc degeneration and regenerative therapy. Current Stem Cell Research & Therapy. 10: 339-52. PMID 25764196 DOI: 10.2174/1574888X10666150312102948  0.741
2015 Illien-Junger S, Grosjean F, Laudier DM, Vlassara H, Striker GE, Iatridis JC. Erratum: Combined anti-inflammatory and anti-age drug treatments have a protective effect on intervertebral discs in mice with diabetes (PLoS ONE (2013) 8:5 (e64302) doi:10.1371/journal.pone.0064302) Plos One. 10. PMID 25742367 DOI: 10.1371/Journal.Pone.0119112  0.687
2015 Walter BA, Likhitpanichkul M, Illien-Junger S, Roughley PJ, Hecht AC, Iatridis JC. TNFα transport induced by dynamic loading alters biomechanics of intact intervertebral discs. Plos One. 10: e0118358. PMID 25734788 DOI: 10.1371/Journal.Pone.0118358  0.795
2015 Lai A, Moon A, Purmessur D, Skovrlj B, Winkelstein BA, Cho SK, Hecht AC, Iatridis JC. Assessment of functional and behavioral changes sensitive to painful disc degeneration. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 755-64. PMID 25731955 DOI: 10.1002/Jor.22833  0.801
2015 Illien-Jünger S, Lu Y, Qureshi SA, Hecht AC, Cai W, Vlassara H, Striker GE, Iatridis JC. Chronic ingestion of advanced glycation end products induces degenerative spinal changes and hypertrophy in aging pre-diabetic mice. Plos One. 10: e0116625. PMID 25668621 DOI: 10.1371/Journal.Pone.0116625  0.709
2015 Purmessur D, Cornejo MC, Cho SK, Roughley PJ, Linhardt RJ, Hecht AC, Iatridis JC. Intact glycosaminoglycans from intervertebral disc-derived notochordal cell-conditioned media inhibit neurite growth while maintaining neuronal cell viability. The Spine Journal : Official Journal of the North American Spine Society. 15: 1060-9. PMID 25661435 DOI: 10.1016/J.Spinee.2015.02.003  0.702
2015 Cornejo MC, Cho SK, Giannarelli C, Iatridis JC, Purmessur D. Soluble factors from the notochordal-rich intervertebral disc inhibit endothelial cell invasion and vessel formation in the presence and absence of pro-inflammatory cytokines. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 23: 487-96. PMID 25534363 DOI: 10.1016/J.Joca.2014.12.010  0.692
2015 Risbud MV, Schoepflin ZR, Mwale F, Kandel RA, Grad S, Iatridis JC, Sakai D, Hoyland JA. Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 33: 283-93. PMID 25411088 DOI: 10.1002/Jor.22789  0.607
2015 Walter BA, Likhitpanichkul M, Illien-Junger S, Roughley PJ, Hecht AC, Iatridis JC. TNFα transport induced by dynamic loading alters biomechanics of intact intervertebral discs Plos One. 10. DOI: 10.1371/journal.pone.0118358  0.773
2014 Walter BA, Torre OM, Laudier D, Naidich TP, Hecht AC, Iatridis JC. Form and function of the intervertebral disc in health and disease: a morphological and stain comparison study. Journal of Anatomy. PMID 25424497 DOI: 10.1111/Joa.12258  0.787
2014 Likhitpanichkul M, Dreischarf M, Illien-Junger S, Walter BA, Nukaga T, Long RG, Sakai D, Hecht AC, Iatridis JC. Fibrin-genipin adhesive hydrogel for annulus fibrosus repair: Performance evaluation with large animal organ culture, in situ biomechanics, and in vivo degradation tests European Cells and Materials. 28: 25-38. PMID 25036053 DOI: 10.22203/Ecm.V028A03  0.809
2014 Frohbergh M, Ge Y, Meng F, Karabul N, Solyom A, Lai A, Iatridis J, Schuchman EH, Simonaro CM. Dose responsive effects of subcutaneous pentosan polysulfate injection in mucopolysaccharidosis type VI rats and comparison to oral treatment. Plos One. 9: e100882. PMID 24964042 DOI: 10.1371/Journal.Pone.0100882  0.706
2014 Lu Y, Guzman JZ, Purmessur D, Iatridis JC, Hecht AC, Qureshi SA, Cho SK. Nonoperative management of discogenic back pain: a systematic review. Spine. 39: 1314-24. PMID 24827515 DOI: 10.1097/Brs.0000000000000401  0.667
2014 Benneker LM, Andersson G, Iatridis JC, Sakai D, Härtl R, Ito K, Grad S. Cell therapy for intervertebral disc repair: advancing cell therapy from bench to clinics. European Cells & Materials. 27: 5-11. PMID 24802611 DOI: 10.22203/Ecm.V027Sa02  0.348
2014 Illien-Jünger S, Lu Y, Purmessur D, Mayer JE, Walter BA, Roughley PJ, Qureshi SA, Hecht AC, Iatridis JC. Detrimental effects of discectomy on intervertebral disc biology can be decelerated by growth factor treatment during surgery: a large animal organ culture model. The Spine Journal : Official Journal of the North American Spine Society. 14: 2724-32. PMID 24768749 DOI: 10.1016/J.Spinee.2014.04.017  0.789
2014 Walter BA, Illien-Jünger S, Nasser PR, Hecht AC, Iatridis JC. Development and validation of a bioreactor system for dynamic loading and mechanical characterization of whole human intervertebral discs in organ culture Journal of Biomechanics. 47: 2095-2101. PMID 24725441 DOI: 10.1016/J.Jbiomech.2014.03.015  0.805
2014 Guterl CC, Torre OM, Purmessur D, Dave K, Likhitpanichkul M, Hecht AC, Nicoll SB, Iatridis JC. Characterization of mechanics and cytocompatibility of fibrin-genipin annulus fibrosus sealant with the addition of cell adhesion molecules. Tissue Engineering. Part A. 20: 2536-45. PMID 24684314 DOI: 10.1089/Ten.Tea.2012.0714  0.794
2014 Iatridis JC, Purmessur D, Cornejo M, Cho SK, Hecht AC. Notochordal Cell-Derived Therapies for Painful Disc Degeneration Global Spine Journal. 4: s-0034-1376751-s-003. DOI: 10.1055/S-0034-1376751  0.699
2014 A Walter B, Torre OM, Illien-Junger S, Laudier DM, Iatridis JC. Form and Function of the intervertebral Disc: Human Organ Culture and Histological Stain Comparison Study Global Spine Journal. 4: s-0034-1376615-s-003. DOI: 10.1055/S-0034-1376615  0.788
2014 Skovrlj B, Purmessur D, Cho SK, Hecht A, Iatridis JC. Effect of Lumbar Intradiscal Injection of Tumor Necrosis Factor-Alpha and Nerve Growth Factor/Vascular Endothelial Growth Factor on Disc Degeneration, Pain Behavior and Neurovascular Ingrowth in an In Vivo Rat Model The Spine Journal. 14: S84. DOI: 10.1016/J.Spinee.2014.08.216  0.682
2014 Illien-Jünger S, Walter BA, Mayer JE, Hecht AC, Iatridis JC. Intervertebral disc culture models and their applications to study pathogenesis and repair The Intervertebral Disc: Molecular and Structural Studies of the Disc in Health and Disease. 2147483647: 353-371. DOI: 10.1007/978-3-7091-1535-0_22  0.616
2013 Purmessur D, Cornejo MC, Cho SK, Hecht AC, Iatridis JC. Notochordal cell-derived therapeutic strategies for discogenic back pain. Global Spine Journal. 3: 201-18. PMID 24436871 DOI: 10.1055/S-0033-1350053  0.708
2013 Purmessur D, Guterl CC, Cho SK, Cornejo MC, Lam YW, Ballif BA, Laudier JC, Iatridis JC. Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development. Arthritis Research & Therapy. 15: R122. PMID 24427812 DOI: 10.1186/Ar4302  0.79
2013 Illien-Junger S, Grosjean F, Laudier DM, Vlassara H, Striker GE, Iatridis JC. Combined anti-inflammatory and anti-AGE drug treatments have a protective effect on intervertebral discs in mice with diabetes. Plos One. 8: e64302. PMID 23691192 DOI: 10.1371/Journal.Pone.0064302  0.702
2013 Antoniou J, Epure LM, Michalek AJ, Grant MP, Iatridis JC, Mwale F. Analysis of quantitative magnetic resonance imaging and biomechanical parameters on human discs with different grades of degeneration. Journal of Magnetic Resonance Imaging : Jmri. 38: 1402-14. PMID 23633131 DOI: 10.1002/Jmri.24120  0.644
2013 Purmessur D, Walter BA, Roughley PJ, Laudier DM, Hecht AC, Iatridis J. A role for TNFα in intervertebral disc degeneration: a non-recoverable catabolic shift. Biochemical and Biophysical Research Communications. 433: 151-6. PMID 23438440 DOI: 10.1016/J.Bbrc.2013.02.034  0.802
2013 Iatridis JC, Nicoll SB, Michalek AJ, Walter BA, Gupta MS. Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its repair? The Spine Journal : Official Journal of the North American Spine Society. 13: 243-62. PMID 23369494 DOI: 10.1016/J.Spinee.2012.12.002  0.785
2013 Schuchman EH, Ge Y, Lai A, Borisov Y, Faillace M, Eliyahu E, He X, Iatridis J, Vlassara H, Striker G, Simonaro CM. Pentosan Polysulfate: A Novel Therapy for the Mucopolysaccharidoses Plos One. 8. PMID 23365668 DOI: 10.1371/Journal.Pone.0054459  0.704
2013 Lai A, Simonaro CM, Schuchman EH, Ge Y, Laudier DM, Iatridis JC. Structural, compositional, and biomechanical alterations of the lumbar spine in rats with mucopolysaccharidosis type VI (Maroteaux-Lamy syndrome). Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 31: 621-31. PMID 23192728 DOI: 10.1002/Jor.22281  0.736
2013 Abbott RD, Purmessur D, Monsey RD, Brigstock DR, Laudier DM, Iatridis JC. Degenerative grade affects the responses of human nucleus pulposus cells to Link-N, CTGF, and TGFβ3 Journal of Spinal Disorders and Techniques. 26: E86-E94. PMID 22907063 DOI: 10.1097/Bsd.0B013E31826E0Ca4  0.799
2013 Abbott RD, Koptiuch C, Iatridis JC, Howe AK, Badger GJ, Langevin HM. Stress and matrix-responsive cytoskeletal remodeling in fibroblasts Journal of Cellular Physiology. 228: 50-57. PMID 22552950 DOI: 10.1002/Jcp.24102  0.719
2012 Guterl CC, See EY, Blanquer SBG, Pandit A, Ferguson SJ, Benneker LM, Grijpma DW, Sakai D, Eglin D, Alini M, Iatridis JC, Grad S. Challenges and strategies in the repair of ruptured annulus fibrosus European Cells and Materials. 25: 1-21. PMID 23283636 DOI: 10.22203/Ecm.V025A01  0.805
2012 Michalek AJ, Iatridis JC. Height and torsional stiffness are most sensitive to annular injury in large animal intervertebral discs. The Spine Journal : Official Journal of the North American Spine Society. 12: 425-32. PMID 22627276 DOI: 10.1016/J.Spinee.2012.04.001  0.672
2012 Abbott RD, Howe AK, Langevin HM, Iatridis JC. Live free or die: Stretch-induced apoptosis occurs when adaptive reorientation of annulus fibrosus cells is restricted Biochemical and Biophysical Research Communications. 421: 361-366. PMID 22516752 DOI: 10.1016/J.Bbrc.2012.04.018  0.714
2012 Michalek AJ, Gardner-Morse MG, Iatridis JC. Large residual strains are present in the intervertebral disc annulus fibrosus in the unloaded state Journal of Biomechanics. 45: 1227-1231. PMID 22342138 DOI: 10.1016/J.Jbiomech.2012.01.042  0.664
2012 Abbott RD, Purmessur D, Monsey RD, Iatridis JC. Regenerative potential of TGFβ3 + Dex and notochordal cell conditioned media on degenerated human intervertebral disc cells Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 30: 482-488. PMID 21866573 DOI: 10.1002/Jor.21534  0.8
2012 Guterl CC, Kim T, Nicoll SB, Iatridis JC. Genipin-crosslinked fibrin hydrogels modified with collagen or fibronectin as an annulus fibrosus sealant Asme 2012 Summer Bioengineering Conference, Sbc 2012. 1151-1152. DOI: 10.1115/SBC2012-80913  0.781
2012 Mwale F, Epure LM, Michalek A, Iatridis J, Antoniou J. Can Quantitative Magnetic Resonance Imaging Predict Mechanical Behavior of Human Intervertebral Disks with Different Grades of Degeneration? Global Spine Journal. 2: s-0032-1319870-s-003. DOI: 10.1055/S-0032-1319870  0.664
2012 Purmessur D, Cornejo MC, Cho S, Stock I, Iatridis J. Notochordal Cell Conditioned Medium Inhibits Neurite Outgrowth and Maintains Neural Cell Viability Global Spine Journal. 2: s-0032-1319847-s-003. DOI: 10.1055/S-0032-1319847  0.677
2012 Koehler SM, Purmessur D, Iatridis JC, Hecht A, Qureshi S, Cho SK. Does BMP-2 Really Cause Cancer? A Systematic Review of the Literature The Spine Journal. 12: S90. DOI: 10.1016/J.Spinee.2012.08.252  0.643
2011 Michalek AJ, Iatridis JC. Penetrating annulus fibrosus injuries affect dynamic compressive behaviors of the intervertebral disc via altered fluid flow: an analytical interpretation. Journal of Biomechanical Engineering. 133: 084502. PMID 21950904 DOI: 10.1115/1.4004915  0.677
2011 Purmessur D, Schek RM, Abbott RD, Ballif BA, Godburn KE, Iatridis JC. Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells. Arthritis Research & Therapy. 13: R81. PMID 21627827 DOI: 10.1186/Ar3344  0.79
2011 Walter BA, Korecki CL, Purmessur D, Roughley PJ, Michalek AJ, Iatridis JC. Complex loading affects intervertebral disc mechanics and biology. Osteoarthritis and Cartilage / Oars, Osteoarthritis Research Society. 19: 1011-8. PMID 21549847 DOI: 10.1016/J.Joca.2011.04.005  0.789
2011 Langevin HM, Bouffard NA, Fox JR, Palmer BM, Wu J, Iatridis JC, Barnes WD, Badger GJ, Howe AK. Fibroblast cytoskeletal remodeling contributes to connective tissue tension. Journal of Cellular Physiology. 226: 1166-75. PMID 20945345 DOI: 10.1002/Jcp.22442  0.348
2011 Barbir A, Godburn KE, Michalek AJ, Lai A, Monsey RD, Iatridis JC. Effects of torsion on intervertebral disc gene expression and biomechanics, using a rat tail model. Spine. 36: 607-14. PMID 20736890 DOI: 10.1097/Brs.0B013E3181D9B58B  0.776
2011 Stokes IA, Laible JP, Gardner-Morse MG, Costi JJ, Iatridis JC. Refinement of elastic, poroelastic, and osmotic tissue properties of intervertebral disks to analyze behavior in compression. Annals of Biomedical Engineering. 39: 122-31. PMID 20711754 DOI: 10.1007/S10439-010-0140-1  0.655
2011 Abbott RD, Purmessur D, Monsey RD, Iatridis JC. Regenerative potential of TGFβ3+Dex and notochordal cell conditioned media on degenerated human intervertebral disc cells Journal of Orthopaedic Research. DOI: 10.1002/jor.21534  0.8
2010 Michalek AJ, Buckley MR, Bonassar LJ, Cohen I, Iatridis JC. The effects of needle puncture injury on microscale shear strain in the intervertebral disc annulus fibrosus. The Spine Journal : Official Journal of the North American Spine Society. 10: 1098-105. PMID 20971041 DOI: 10.1016/J.Spinee.2010.09.015  0.691
2010 Korecki CL, Taboas JM, Tuan RS, Iatridis JC. Notochordal cell conditioned medium stimulates mesenchymal stem cell differentiation toward a young nucleus pulposus phenotype. Stem Cell Research & Therapy. 1: 18. PMID 20565707 DOI: 10.1186/Scrt18  0.792
2010 Michalek AJ, Funabashi KL, Iatridis JC. Needle puncture injury of the rat intervertebral disc affects torsional and compressive biomechanics differently. European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 19: 2110-6. PMID 20544231 DOI: 10.1007/S00586-010-1666-5  0.682
2010 Barbir A, Michalek AJ, Abbott RD, Iatridis JC. Effects of enzymatic digestion on compressive properties of rat intervertebral discs. Journal of Biomechanics. 43: 1067-73. PMID 20116063 DOI: 10.1016/J.Jbiomech.2009.12.005  0.802
2009 Iatridis JC, Michalek AJ, Purmessur D, Korecki CL. Localized Intervertebral Disc Injury Leads to Organ Level Changes in Structure, Cellularity, and Biosynthesis. Cellular and Molecular Bioengineering. 2: 437-447. PMID 21179399 DOI: 10.1007/S12195-009-0072-8  0.803
2009 Michalek AJ, Buckley MR, Bonassar LJ, Cohen I, Iatridis JC. Measurement of local strains in intervertebral disc anulus fibrosus tissue under dynamic shear: contributions of matrix fiber orientation and elastin content. Journal of Biomechanics. 42: 2279-85. PMID 19664773 DOI: 10.1016/J.Jbiomech.2009.06.047  0.67
2009 Wuertz K, Godburn K, MacLean JJ, Barbir A, Donnelly JS, Roughley PJ, Alini M, Iatridis JC. In vivo remodeling of intervertebral discs in response to short- and long-term dynamic compression. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 27: 1235-42. PMID 19274755 DOI: 10.1002/Jor.20867  0.795
2009 Wuertz K, Godburn K, Iatridis JC. MSC response to pH levels found in degenerating intervertebral discs. Biochemical and Biophysical Research Communications. 379: 824-9. PMID 19133233 DOI: 10.1016/J.Bbrc.2008.12.145  0.34
2009 Korecki CL, Kuo CK, Tuan RS, Iatridis JC. Intervertebral disc cell response to dynamic compression is age and frequency dependent. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 27: 800-6. PMID 19058142 DOI: 10.1002/Jor.20814  0.811
2008 Mwale F, Iatridis JC, Antoniou J. Quantitative MRI as a diagnostic tool of intervertebral disc matrix composition and integrity. European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 17: 432-40. PMID 19005703 DOI: 10.1007/S00586-008-0744-4  0.31
2008 Wuertz K, Godburn K, Neidlinger-Wilke C, Urban J, Iatridis JC. Behavior of mesenchymal stem cells in the chemical microenvironment of the intervertebral disc. Spine. 33: 1843-9. PMID 18670337 DOI: 10.1097/Brs.0B013E31817B8F53  0.302
2008 Costi JJ, Stokes IA, Gardner-Morse MG, Iatridis JC. Frequency-dependent behavior of the intervertebral disc in response to each of six degree of freedom dynamic loading: solid phase and fluid phase contributions. Spine. 33: 1731-8. PMID 18628705 DOI: 10.1097/Brs.0B013E31817Bb116  0.639
2008 Korecki CL, MacLean JJ, Iatridis JC. Dynamic compression effects on intervertebral disc mechanics and biology. Spine. 33: 1403-9. PMID 18520935 DOI: 10.1097/Brs.0B013E318175Cae7  0.794
2008 Rogers R, Norian J, Malik M, Christman G, Abu-Asab M, Chen F, Korecki C, Iatridis J, Catherino WH, Tuan RS, Dhillon N, Leppert P, Segars JH. Mechanical homeostasis is altered in uterine leiomyoma. American Journal of Obstetrics and Gynecology. 198: 474.e1-11. PMID 18395046 DOI: 10.1016/J.Ajog.2007.11.057  0.791
2008 Korecki CL, Costi JJ, Iatridis JC. Needle puncture injury affects intervertebral disc mechanics and biology in an organ culture model. Spine. 33: 235-41. PMID 18303454 DOI: 10.1097/Brs.0B013E3181624504  0.791
2008 Mwale F, Demers CN, Michalek AJ, Beaudoin G, Goswami T, Beckman L, Iatridis JC, Antoniou J. Evaluation of quantitative magnetic resonance imaging, biochemical and mechanical properties of trypsin-treated intervertebral discs under physiological compression loading. Journal of Magnetic Resonance Imaging : Jmri. 27: 563-73. PMID 18219615 DOI: 10.1002/Jmri.21242  0.67
2008 MacLean JJ, Roughley PJ, Monsey RD, Alini M, Iatridis JC. In vivo intervertebral disc remodeling: kinetics of mRNA expression in response to a single loading event. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 26: 579-88. PMID 18176944 DOI: 10.1002/Jor.20560  0.74
2007 Masuoka K, Michalek AJ, MacLean JJ, Stokes IA, Iatridis JC. Different effects of static versus cyclic compressive loading on rat intervertebral disc height and water loss in vitro. Spine. 32: 1974-9. PMID 17700443 DOI: 10.1097/Brs.0B013E318133D591  0.785
2007 Korecki CL, MacLean JJ, Iatridis JC. Characterization of an in vitro intervertebral disc organ culture system. European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 16: 1029-37. PMID 17629763 DOI: 10.1007/S00586-007-0327-9  0.805
2007 Iatridis JC, MacLean JJ, O'Brien M, Stokes IA. Measurements of proteoglycan and water content distribution in human lumbar intervertebral discs. Spine. 32: 1493-7. PMID 17572617 DOI: 10.1097/Brs.0B013E318067Dd3F  0.72
2007 Costi JJ, Stokes IA, Gardner-Morse M, Laible JP, Scoffone HM, Iatridis JC. Direct measurement of intervertebral disc maximum shear strain in six degrees of freedom: motions that place disc tissue at risk of injury. Journal of Biomechanics. 40: 2457-66. PMID 17198708 DOI: 10.1016/J.Jbiomech.2006.11.006  0.663
2007 Michalek AJ, Iatridis JC. A numerical study to determine pericellular matrix modulus and evaluate its effects on the micromechanical environment of chondrocytes. Journal of Biomechanics. 40: 1405-9. PMID 16867304 DOI: 10.1016/J.Jbiomech.2006.05.025  0.672
2007 MacLean JJ, Owen JP, Iatridis JC. Role of endplates in contributing to compression behaviors of motion segments and intervertebral discs. Journal of Biomechanics. 40: 55-63. PMID 16427060 DOI: 10.1016/J.Jbiomech.2005.11.013  0.742
2007 Costi J, Stokes I, Gardner-Morse M, Laible J, Scoffone H, Iatridis J. LATERAL BENDING AND FLEXION PLACE INTERVERTEBRAL DISC TISSUE AT GREATEST RISK OF INJURY Journal of Biomechanics. 40: S596. DOI: 10.1016/S0021-9290(07)70584-5  0.655
2007 Korecki C, Costi J, Iatridis J. Needle Puncture Affects Intervertebral Disc Mechanics And Biology In An Organ Culture Model Journal of Biomechanics. 40. DOI: 10.1016/S0021-9290(07)70307-X  0.784
2007 Costi J, Stokes I, Gardner-Morse M, Lubinski J, Iatridis J. FREQUENCY DEPENDENT POROELASTIC AND VISCOELASTIC CONTRIBUTIONS OF THE INTERVERTEBRAL DISC IN RESPONSE TO SIX DEGREE OF FREEDOM CYCLIC LOADING Journal of Biomechanics. 40: S310. DOI: 10.1016/S0021-9290(07)70306-8  0.644
2006 Perie DS, Maclean JJ, Owen JP, Iatridis JC. Correlating material properties with tissue composition in enzymatically digested bovine annulus fibrosus and nucleus pulposus tissue. Annals of Biomedical Engineering. 34: 769-77. PMID 16598654 DOI: 10.1007/S10439-006-9091-Y  0.736
2006 Iatridis JC, MacLean JJ, Roughley PJ, Alini M. Effects of mechanical loading on intervertebral disc metabolism in vivo. The Journal of Bone and Joint Surgery. American Volume. 88: 41-6. PMID 16595442 DOI: 10.2106/Jbjs.E.01407  0.757
2006 Lee CR, Iatridis JC, Poveda L, Alini M. In vitro organ culture of the bovine intervertebral disc: effects of vertebral endplate and potential for mechanobiology studies. Spine. 31: 515-22. PMID 16508544 DOI: 10.1097/01.Brs.0000201302.59050.72  0.633
2006 Périé D, Iatridis JC, Demers CN, Goswami T, Beaudoin G, Mwale F, Antoniou J. Assessment of compressive modulus, hydraulic permeability and matrix content of trypsin-treated nucleus pulposus using quantitative MRI. Journal of Biomechanics. 39: 1392-400. PMID 15970200 DOI: 10.1016/J.Jbiomech.2005.04.015  0.301
2005 Périé D, Korda D, Iatridis JC. Confined compression experiments on bovine nucleus pulposus and annulus fibrosus: sensitivity of the experiment in the determination of compressive modulus and hydraulic permeability. Journal of Biomechanics. 38: 2164-71. PMID 16154403 DOI: 10.1016/J.Jbiomech.2004.10.002  0.326
2005 MacLean JJ, Lee CR, Alini M, Iatridis JC. The effects of short-term load duration on anabolic and catabolic gene expression in the rat tail intervertebral disc. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 23: 1120-7. PMID 16140193 DOI: 10.1016/J.Orthres.2005.01.020  0.792
2005 Lee CR, Grad S, Maclean JJ, Iatridis JC, Alini M. Effect of mechanical loading on mRNA levels of common endogenous controls in articular chondrocytes and intervertebral disk. Analytical Biochemistry. 341: 372-5. PMID 15907885 DOI: 10.1016/J.Ab.2004.10.005  0.78
2005 Iatridis JC, MaClean JJ, Ryan DA. Mechanical damage to the intervertebral disc annulus fibrosus subjected to tensile loading. Journal of Biomechanics. 38: 557-65. PMID 15652555 DOI: 10.1016/J.Jbiomech.2004.03.038  0.741
2005 Langevin HM, Bouffard NA, Badger GJ, Iatridis JC, Howe AK. Dynamic fibroblast cytoskeletal response to subcutaneous tissue stretch ex vivo and in vivo. American Journal of Physiology. Cell Physiology. 288: C747-56. PMID 15496476 DOI: 10.1152/Ajpcell.00420.2004  0.354
2004 An HS, Anderson PA, Haughton VM, Iatridis JC, Kang JD, Lotz JC, Natarajan RN, Oegema TR, Roughley P, Setton LA, Urban JP, Videman T, Andersson GB, Weinstein JN. Introduction: disc degeneration: summary. Spine. 29: 2677-8. PMID 15564916 DOI: 10.1097/01.Brs.0000147573.88916.C6  0.556
2004 Maclean JJ, Lee CR, Alini M, Iatridis JC. Anabolic and catabolic mRNA levels of the intervertebral disc vary with the magnitude and frequency of in vivo dynamic compression. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 22: 1193-200. PMID 15475197 DOI: 10.1016/J.Orthres.2004.04.004  0.787
2003 Iatridis JC, Wu J, Yandow JA, Langevin HM. Subcutaneous tissue mechanical behavior is linear and viscoelastic under uniaxial tension. Connective Tissue Research. 44: 208-17. PMID 14660091 DOI: 10.1080/03008200390244069  0.318
2003 MacLean JJ, Lee CR, Grad S, Ito K, Alini M, Iatridis JC. Effects of immobilization and dynamic compression on intervertebral disc cell gene expression in vivo. Spine. 28: 973-81. PMID 12768134 DOI: 10.1097/01.Brs.0000061985.15849.A9  0.796
1999 Iatridis JC, Kumar S, Foster RJ, Weidenbaum M, Mow VC. Shear mechanical properties of human lumbar annulus fibrosus Journal of Orthopaedic Research. 17: 732-737. PMID 10569484 DOI: 10.1002/Jor.1100170517  0.643
1999 Gu WY, Mao XG, Rawlins BA, Iatridis JC, Foster RJ, Sun DN, Weidenbaum M, Mow VC. Streaming potential of human lumbar anulus fibrosus is anisotropic and affected by disc degeneration. Journal of Biomechanics. 32: 1177-82. PMID 10541067 DOI: 10.1016/S0021-9290(99)00118-9  0.783
1999 Iatridis JC, Mente PL, Stokes IAF, Aronsson DD, Alini M. Compression-induced changes in intervertebral disc properties in a rat tail model Spine. 24: 996-1002. PMID 10332792 DOI: 10.1097/00007632-199905150-00013  0.384
1998 Iatridis JC, Setton LA, Foster RJ, Rawlins BA, Weidenbaum M, Mow VC. Degeneration affects the anisotropic and nonlinear behaviors of human anulus fibrosus in compression Journal of Biomechanics. 31: 535-544. PMID 9755038 DOI: 10.1016/S0021-9290(98)00046-3  0.726
1998 Stokes IAF, Aronsson DD, Spence H, Iatridis JC. Mechanical Modulation of Intervertebral Disc Thickness in Growing Rat Tails Journal of Spinal Disorders. 11: 261???265. DOI: 10.1097/00002517-199806000-00015  0.331
1997 Iatridis JC, Setton LA, Weidenbaum M, Mow. VC. The viscoelastic behavior of the non-degenerate human lumbar nucleus pulposus in shear Journal of Biomechanics. 30: 1005-1013. PMID 9391867 DOI: 10.1016/S0021-9290(97)00069-9  0.711
1997 Iatridis JC, Setton LA, Weidenbaum M, Mow VC. Alterations in the mechanical behavior of the human lumbar nucleus pulposus with degeneration and aging Journal of Orthopaedic Research. 15: 318-322. PMID 9167638 DOI: 10.1002/Jor.1100150224  0.728
1996 Zhu W, Iatridis JC, Hlibczuk V, Ratcliffe A, Mow VC. Determination of collagen-proteoglycan interactions in vitro Journal of Biomechanics. 29: 773-783. PMID 9147974 DOI: 10.1016/0021-9290(95)00136-0  0.63
1996 Iatridis JC, Weidenbaum M, Setton LA, Mow CV. Is the nucleus pulposus a solid or a fluid? Mechanical behaviors of the nucleus pulposus of the human intervertebral disc Spine. 21: 1174-1184. PMID 8727192 DOI: 10.1097/00007632-199605150-00009  0.551
1996 Ebara S, Iatridis JC, Setton LA, Foster RJ, Van Mow C, Weidenbaum M. Tensile properties of nondegenerate human lumbar anulus fibrosus Spine. 21: 452-461. PMID 8658249 DOI: 10.1097/00007632-199602150-00009  0.551
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