| Year |
Citation |
Score |
| 2023 |
Zehnaker A, Vallet A, Gourdon J, Sarti C, Jugnarain V, Haj Hassan M, Mathias L, Gauthier C, Raynaud P, Boulo T, Beauclair L, Bigot Y, Casarini L, Crépieux P, Poupon A, ... ... Jean-Alphonse F, et al. Combined Multiplexed Phage Display, High-Throughput Sequencing, and Functional Assays as a Platform for Identifying Modulatory VHHs Targeting the FSHR. International Journal of Molecular Sciences. 24. PMID 37958944 DOI: 10.3390/ijms242115961 |
0.361 |
|
| 2023 |
Raynaud P, Jugnarain V, Vaugrente O, Vallet A, Boulo T, Gauthier C, Inoue A, Sibille N, Gauthier C, Jean-Alphonse F, Reiter E, Crépieux P, Bruneau G. A single-domain intrabody targeting the follicle-stimulating hormone receptor impacts FSH-induced G protein-dependent signalling. Febs Letters. PMID 37923554 DOI: 10.1002/1873-3468.14765 |
0.506 |
|
| 2023 |
Klett D, Pellissier L, Lomet D, Derouin-Tochon F, Robert V, Nguyen TMD, Duittoz A, Reiter E, Locatelli Y, Dupont J, Dardente H, Jean-Alphonse F, Combarnous Y. Highly-Sensitive In Vitro Bioassays for FSH, TSH, PTH, Kp, and OT in Addition to LH in Mouse Leydig Tumor Cell. International Journal of Molecular Sciences. 24. PMID 37569429 DOI: 10.3390/ijms241512047 |
0.387 |
|
| 2022 |
Raynaud P, Gauthier C, Jugnarain V, Jean-Alphonse F, Reiter E, Bruneau G, Crépieux P. Intracellular VHHs to monitor and modulate GPCR signaling. Frontiers in Endocrinology. 13: 1048601. PMID 36465650 DOI: 10.3389/fendo.2022.1048601 |
0.45 |
|
| 2022 |
Peña KA, White AD, Savransky S, Castillo IP, Jean-Alphonse FG, Gardella TJ, Sutkeviciute I, Vilardaga JP. Biased GPCR signaling by the native parathyroid hormone-related protein 1-141 relative to its N-terminal fragment 1-36. The Journal of Biological Chemistry. 102332. PMID 35933010 DOI: 10.1016/j.jbc.2022.102332 |
0.434 |
|
| 2021 |
Jean-Alphonse FG, Sposini S. Confocal and TIRF microscopy based approaches to visualize arrestin trafficking in living cells. Methods in Cell Biology. 166: 179-203. PMID 34752332 DOI: 10.1016/bs.mcb.2021.06.009 |
0.359 |
|
| 2021 |
White AD, Peña KA, Clark LJ, Maria CS, Liu S, Jean-Alphonse FG, Lee JY, Lei S, Cheng Z, Tu CL, Fang F, Szeto N, Gardella TJ, Xiao K, Gellman SH, et al. Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation. Science Signaling. 14: eabc5944. PMID 34609896 DOI: 10.1126/scisignal.abc5944 |
0.314 |
|
| 2021 |
De Pascali F, Ayoub MA, Benevelli R, Sposini S, Lehoux J, Gallay N, Raynaud P, Landomiel F, Jean-Alphonse F, Gauthier C, Pellissier LP, Crépieux P, Poupon A, Inoue A, Joubert N, et al. Pharmacological Characterization of Low Molecular Weight Biased Agonists at the Follicle Stimulating Hormone Receptor. International Journal of Molecular Sciences. 22. PMID 34576014 DOI: 10.3390/ijms22189850 |
0.316 |
|
| 2020 |
Clark LJ, Krieger J, White AD, Bondarenko V, Lei S, Fang F, Lee JY, Doruker P, Böttke T, Jean-Alphonse F, Tang P, Gardella TJ, Xiao K, Sutkeviciute I, Coin I, et al. Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation. Nature Chemical Biology. PMID 32632293 DOI: 10.1038/S41589-020-0567-0 |
0.569 |
|
| 2020 |
White AD, Jean-Alphonse FG, Fang F, Peña KA, Liu S, König GM, Inoue A, Aslanoglou D, Gellman SH, Kostenis E, Xiao K, Vilardaga JP. G-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR. Proceedings of the National Academy of Sciences of the United States of America. PMID 32184323 DOI: 10.1073/Pnas.1918158117 |
0.356 |
|
| 2019 |
Liu S, Jean-Alphonse FG, White AD, Wootten D, Sexton PM, Gardella TJ, Vilardaga JP, Gellman SH. Use of Backbone Modification To Enlarge the Spatiotemporal Diversity of Parathyroid Hormone Receptor-1 Signaling via Biased Agonism. Journal of the American Chemical Society. PMID 31496241 DOI: 10.1021/Jacs.9B04179 |
0.382 |
|
| 2019 |
Zhao LH, Ma S, Sutkeviciute I, Shen DD, Zhou XE, de Waal PW, Li CY, Kang Y, Clark LJ, Jean-Alphonse FG, White AD, Yang D, Dai A, Cai X, Chen J, et al. Structure and dynamics of the active human parathyroid hormone receptor-1. Science (New York, N.Y.). 364: 148-153. PMID 30975883 DOI: 10.1126/science.aav7942 |
0.492 |
|
| 2019 |
Landomiel F, De Pascali F, Raynaud P, Jean-Alphonse F, Yvinec R, Pellissier LP, Bozon V, Bruneau G, Crépieux P, Poupon A, Reiter E. Biased Signaling and Allosteric Modulation at the FSHR. Frontiers in Endocrinology. 10: 148. PMID 30930853 DOI: 10.3389/Fendo.2019.00148 |
0.551 |
|
| 2019 |
White AD, Fang F, Jean-Alphonse FG, Clark LJ, An HJ, Liu H, Zhao Y, Reynolds SL, Lee S, Xiao K, Sutkeviciute I, Vilardaga JP. Ca allostery in PTH-receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718391 DOI: 10.1073/Pnas.1814670116 |
0.388 |
|
| 2019 |
Zhang Q, Xiao K, Paredes JM, Mamonova T, Sneddon WB, Liu H, Wang D, Li S, McGarvey JC, Uehling D, Al-Awar R, Joseph B, Jean-Alphonse F, Orte A, Friedman PA. Parathyroid hormone initiates dynamic NHERF1 phosphorylation cycling and conformational changes that regulate NPT2A-dependent phosphate transport. The Journal of Biological Chemistry. PMID 30696771 DOI: 10.1074/Jbc.Ra119.007421 |
0.354 |
|
| 2019 |
White A, Sutkeviciute I, Jean-Alphonse F, Xiao K, Vilardaga J. MON-538 Ca2+Allostery in PTH-Receptor Signaling Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Mon-538 |
0.406 |
|
| 2017 |
Sposini S, Jean-Alphonse FG, Ayoub MA, Oqua A, West C, Lavery S, Brosens JJ, Reiter E, Hanyaloglu AC. Integration of GPCR Signaling and Sorting from Very Early Endosomes via Opposing APPL1 Mechanisms. Cell Reports. 21: 2855-2867. PMID 29212031 DOI: 10.1016/j.celrep.2017.11.023 |
0.441 |
|
| 2017 |
Suofu Y, Li W, Jean-Alphonse FG, Jia J, Khattar NK, Li J, Baranov SV, Leronni D, Mihalik AC, He Y, Cecon E, Wehbi VL, Kim J, Heath BE, Baranova OV, et al. Dual role of mitochondria in producing melatonin and driving GPCR signaling to block cytochrome c release. Proceedings of the National Academy of Sciences of the United States of America. PMID 28874589 DOI: 10.1073/Pnas.1705768114 |
0.349 |
|
| 2017 |
Gbahou F, Cecon E, Viault G, Gerbier R, Jean-Alphonse F, Karamitri A, Guillaumet G, Delagrange P, Friedlander RM, Vilardaga JP, Suzenet F, Jockers R. Design and validation of the first cell-impermeant melatonin receptor agonist. British Journal of Pharmacology. PMID 28493341 DOI: 10.1111/Bph.13856 |
0.618 |
|
| 2016 |
Jean-Alphonse FG, Wehbi VL, Chen J, Noda M, Taboas JM, Xiao K, Vilardaga JP. β2-adrenergic receptor control of endosomal PTH receptor signaling via Gβγ. Nature Chemical Biology. PMID 28024151 DOI: 10.1038/Nchembio.2267 |
0.48 |
|
| 2016 |
McGarvey JC, Xiao K, Bowman SL, Mamonova T, Zhang Q, Bisello A, Sneddon WB, Ardura JA, Jean-Alphonse F, Vilardaga JP, Puthenveedu MA, Friedman PA. Actin-Sorting Nexin 27-Retromer Complex Mediates Rapid Parathyroid Hormone Receptor Recycling. The Journal of Biological Chemistry. PMID 27008860 DOI: 10.1074/Jbc.M115.697045 |
0.479 |
|
| 2015 |
Xu Y, Streets AJ, Hounslow AM, Tran U, Jean-Alphonse F, Needham AJ, Vilardaga JP, Wessely O, Williamson MP, Ong AC. The Polycystin-1, Lipoxygenase, and α-Toxin Domain Regulates Polycystin-1 Trafficking. Journal of the American Society of Nephrology : Jasn. PMID 26311459 DOI: 10.1681/Asn.2014111074 |
0.31 |
|
| 2014 |
Nikolopoulou E, Papacleovoulou G, Jean-Alphonse F, Grimaldi G, Parker MG, Hanyaloglu AC, Christian M. Arachidonic acid-dependent gene regulation during preadipocyte differentiation controls adipocyte potential. Journal of Lipid Research. 55: 2479-90. PMID 25325755 DOI: 10.1194/Jlr.M049551 |
0.304 |
|
| 2014 |
Vilardaga JP, Jean-Alphonse FG, Gardella TJ. Endosomal generation of cAMP in GPCR signaling. Nature Chemical Biology. 10: 700-6. PMID 25271346 DOI: 10.1038/Nchembio.1611 |
0.397 |
|
| 2014 |
Gidon A, Al-Bataineh MM, Jean-Alphonse FG, Stevenson HP, Watanabe T, Louet C, Khatri A, Calero G, Pastor-Soler NM, Gardella TJ, Vilardaga JP. Endosomal GPCR signaling turned off by negative feedback actions of PKA and v-ATPase. Nature Chemical Biology. 10: 707-9. PMID 25064832 DOI: 10.1038/Nchembio.1589 |
0.484 |
|
| 2014 |
Jean-Alphonse F, Bowersox S, Chen S, Beard G, Puthenveedu MA, Hanyaloglu AC. Spatially restricted G protein-coupled receptor activity via divergent endocytic compartments. The Journal of Biological Chemistry. 289: 3960-77. PMID 24375413 DOI: 10.1074/Jbc.M113.526350 |
0.571 |
|
| 2011 |
Jean-Alphonse F, Hanyaloglu AC. Regulation of GPCR signal networks via membrane trafficking. Molecular and Cellular Endocrinology. 331: 205-14. PMID 20654691 DOI: 10.1016/J.Mce.2010.07.010 |
0.506 |
|
| 2010 |
Cottet M, Albizu L, Perkovska S, Jean-Alphonse F, Rahmeh R, Orcel H, Méjean C, Granier S, Mendre C, Mouillac B, Durroux T. Past, present and future of vasopressin and oxytocin receptor oligomers, prototypical GPCR models to study dimerization processes. Current Opinion in Pharmacology. 10: 59-66. PMID 19896898 DOI: 10.1016/J.Coph.2009.10.003 |
0.588 |
|
| 2009 |
Jean-Alphonse F, Perkovska S, Frantz MC, Durroux T, Méjean C, Morin D, Loison S, Bonnet D, Hibert M, Mouillac B, Mendre C. Biased agonist pharmacochaperones of the AVP V2 receptor may treat congenital nephrogenic diabetes insipidus. Journal of the American Society of Nephrology : Jasn. 20: 2190-203. PMID 19729439 DOI: 10.1681/Asn.2008121289 |
0.676 |
|
| 2008 |
Granier S, Jean-Alphonse F, Bacqueville D, Monteil A, Pascal R, Poncet J, Guillon G, Boudier L, Arcemisbéhère L, Mouillac B, Bellot G, Déméné H, Mendre C. The multifunctional protein GC1q-R interacts specifically with the i3 loop arginine cluster of the vasopressin V2 receptor Regulatory Peptides. 148: 76-87. PMID 18358546 DOI: 10.1016/J.Regpep.2008.01.007 |
0.581 |
|
| 2006 |
Granier S, Jean-Alphonse F, Déméné H, Guillon G, Pascal R, Mendre C. Design and synthesis of cyclic and linear peptide-agarose tools for baiting interacting protein partners of GPCRs Bioorganic and Medicinal Chemistry Letters. 16: 521-524. PMID 16289816 DOI: 10.1016/J.Bmcl.2005.10.061 |
0.728 |
|
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