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Patrick C.A. van der Wel, Ph.D. - Publications

Affiliations: 
2008-2018 Department of Structural Biology University of Pittsburgh, Pittsburgh, PA, United States 
 2018- Zernike Institute for Advanced Materials University of Groningen, Groningen, Netherlands 
Area:
Solid-state NMR; biophysics; structural biology
Website:
https://www.vanderwellab.org
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Kar K, Baker MA, Lengyel GA, Hoop CL, Kodali R, Byeon IJ, Horne WS, van der Wel PC, Wetzel R. Backbone engineering within a latent β-hairpin structure to design inhibitors of polyglutamine amyloid formation. Journal of Molecular Biology. PMID 27986569 DOI: 10.1016/J.Jmb.2016.12.010  0.4
2016 Merg AD, Boatz JC, Mandal A, Zhao G, Mokashi-Punekar S, Liu C, Wang X, Zhang P, van der Wel PC, Rosi NL. Peptide-Directed Assembly of Single-Helical Gold Nanoparticle Superstructures Exhibiting Intense Chiroptical Activity. Journal of the American Chemical Society. PMID 27726354 DOI: 10.1021/Jacs.6B07322  0.328
2016 Hoop CL, Lin HK, Kar K, Magyarfalvi G, Lamley JM, Boatz JC, Mandal A, Lewandowski JR, Wetzel R, van der Wel PC. Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine core. Proceedings of the National Academy of Sciences of the United States of America. PMID 26831073 DOI: 10.1073/Pnas.1521933113  0.388
2015 Mandal A, Hoop CL, DeLucia M, Kodali R, Kagan VE, Ahn J, van der Wel PC. Structural Changes and Proapoptotic Peroxidase Activity of Cardiolipin-Bound Mitochondrial Cytochrome c. Biophysical Journal. 109: 1873-84. PMID 26536264 DOI: 10.1016/j.bpj.2015.09.016  0.423
2014 Hoop CL, Lin HK, Kar K, Hou Z, Poirier MA, Wetzel R, van der Wel PC. Polyglutamine amyloid core boundaries and flanking domain dynamics in huntingtin fragment fibrils determined by solid-state nuclear magnetic resonance. Biochemistry. 53: 6653-66. PMID 25280367 DOI: 10.1021/Bi501010Q  0.386
2014 Kar K, Arduini I, Drombosky KW, van der Wel PC, Wetzel R. D-polyglutamine amyloid recruits L-polyglutamine monomers and kills cells. Journal of Molecular Biology. 426: 816-29. PMID 24291210 DOI: 10.1016/J.Jmb.2013.11.019  0.323
2013 Li J, van der Wel PC. Spinning-rate encoded chemical shift correlations from rotational resonance solid-state NMR experiments. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 230: 117-24. PMID 23475055 DOI: 10.1016/j.jmr.2013.02.004  0.339
2013 Kar K, Hoop CL, Drombosky KW, Baker MA, Kodali R, Arduini I, van der Wel PC, Horne WS, Wetzel R. β-hairpin-mediated nucleation of polyglutamine amyloid formation. Journal of Molecular Biology. 425: 1183-97. PMID 23353826 DOI: 10.1016/J.Jmb.2013.01.016  0.374
2012 Markley JL, Akutsu H, Asakura T, Baldus M, Boelens R, Bonvin A, Kaptein R, Bax A, Bezsonova I, Gryk MR, Hoch JC, Korzhnev DM, Maciejewski MW, Case D, Chazin WJ, ... ... van der Wel P, et al. In support of the BMRB. Nature Structural & Molecular Biology. 19: 854-60. PMID 22955930 DOI: 10.1038/Nsmb.2371  0.474
2012 van der Wel PC. Domain swapping and amyloid fibril conformation. Prion. 6: 211-6. PMID 22437737 DOI: 10.4161/pri.18987  0.373
2012 Eddy MT, Ong TC, Clark L, Teijido O, van der Wel PC, Garces R, Wagner G, Rostovtseva TK, Griffin RG. Lipid dynamics and protein-lipid interactions in 2D crystals formed with the β-barrel integral membrane protein VDAC1. Journal of the American Chemical Society. 134: 6375-87. PMID 22435461 DOI: 10.1021/Ja300347V  0.519
2012 Hoop CL, Sivanandam VN, Kodali R, Srnec MN, van der Wel PC. Structural characterization of the caveolin scaffolding domain in association with cholesterol-rich membranes. Biochemistry. 51: 90-9. PMID 22142403 DOI: 10.1021/bi201356v  0.437
2011 Lewandowski JR, van der Wel PC, Rigney M, Grigorieff N, Griffin RG. Structural complexity of a composite amyloid fibril. Journal of the American Chemical Society. 133: 14686-98. PMID 21766841 DOI: 10.1021/Ja203736Z  0.572
2011 Li J, Hoop CL, Kodali R, Sivanandam VN, van der Wel PC. Amyloid-like fibrils from a domain-swapping protein feature a parallel, in-register conformation without native-like interactions. The Journal of Biological Chemistry. 286: 28988-95. PMID 21715337 DOI: 10.1074/jbc.M111.261750  0.368
2011 Sivanandam VN, Jayaraman M, Hoop CL, Kodali R, Wetzel R, van der Wel PC. The aggregation-enhancing huntingtin N-terminus is helical in amyloid fibrils. Journal of the American Chemical Society. 133: 4558-66. PMID 21381744 DOI: 10.1021/Ja110715F  0.412
2010 van der Wel PC, Lewandowski JR, Griffin RG. Structural characterization of GNNQQNY amyloid fibrils by magic angle spinning NMR. Biochemistry. 49: 9457-69. PMID 20695483 DOI: 10.1021/Bi100077X  0.608
2010 Debelouchina GT, Bayro MJ, van der Wel PC, Caporini MA, Barnes AB, Rosay M, Maas WE, Griffin RG. Dynamic nuclear polarization-enhanced solid-state NMR spectroscopy of GNNQQNY nanocrystals and amyloid fibrils. Physical Chemistry Chemical Physics : Pccp. 12: 5911-9. PMID 20454733 DOI: 10.1039/C003661G  0.556
2010 De Gortari I, Portella G, Salvatella X, Bajaj VS, van der Wel PC, Yates JR, Segall MD, Pickard CJ, Payne MC, Vendruscolo M. Time averaging of NMR chemical shifts in the MLF peptide in the solid state. Journal of the American Chemical Society. 132: 5993-6000. PMID 20387894 DOI: 10.1021/Ja9062629  0.311
2009 Barnes AB, Andreas LB, Huber M, Ramachandran R, van der Wel PC, Veshtort M, Griffin RG, Mehta MA. High-resolution solid-state NMR structure of alanyl-prolyl-glycine. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 200: 95-100. PMID 19596601 DOI: 10.1016/J.Jmr.2009.06.009  0.477
2009 van der Wel PC, Eddy MT, Ramachandran R, Griffin RG. Targeted 13C-13C distance measurements in a microcrystalline protein via J-decoupled rotational resonance width measurements. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 10: 1656-63. PMID 19565580 DOI: 10.1002/Cphc.200900102  0.485
2009 Barnes AB, Mak-Jurkauskas ML, Matsuki Y, Bajaj VS, van der Wel PC, Derocher R, Bryant J, Sirigiri JR, Temkin RJ, Lugtenburg J, Herzfeld J, Griffin RG. Cryogenic sample exchange NMR probe for magic angle spinning dynamic nuclear polarization. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 198: 261-70. PMID 19356957 DOI: 10.1016/J.Jmr.2009.03.003  0.447
2009 Bajaj VS, van der Wel PC, Griffin RG. Observation of a low-temperature, dynamically driven structural transition in a polypeptide by solid-state NMR spectroscopy. Journal of the American Chemical Society. 131: 118-28. PMID 19067520 DOI: 10.1021/Ja8045926  0.503
2008 Barnes AB, Paëpe GD, van der Wel PC, Hu KN, Joo CG, Bajaj VS, Mak-Jurkauskas ML, Sirigiri JR, Herzfeld J, Temkin RJ, Griffin RG. High-Field Dynamic Nuclear Polarization for Solid and Solution Biological NMR. Applied Magnetic Resonance. 34: 237-263. PMID 19194532 DOI: 10.1007/S00723-008-0129-1  0.519
2008 Maly T, Debelouchina GT, Bajaj VS, Hu KN, Joo CG, Mak-Jurkauskas ML, Sirigiri JR, van der Wel PC, Herzfeld J, Temkin RJ, Griffin RG. Dynamic nuclear polarization at high magnetic fields. The Journal of Chemical Physics. 128: 052211. PMID 18266416 DOI: 10.1063/1.2833582  0.477
2008 Daily AE, Greathouse DV, van der Wel PC, Koeppe RE. Helical distortion in tryptophan- and lysine-anchored membrane-spanning alpha-helices as a function of hydrophobic mismatch: a solid-state deuterium NMR investigation using the geometric analysis of labeled alanines method. Biophysical Journal. 94: 480-91. PMID 17827234 DOI: 10.1529/Biophysj.106.097543  0.647
2007 van der Wel PC, Reed ND, Greathouse DV, Koeppe RE. Orientation and motion of tryptophan interfacial anchors in membrane-spanning peptides. Biochemistry. 46: 7514-24. PMID 17530863 DOI: 10.1021/Bi700082V  0.599
2007 van der Wel PC, Lewandowski JR, Griffin RG. Solid-state NMR study of amyloid nanocrystals and fibrils formed by the peptide GNNQQNY from yeast prion protein Sup35p. Journal of the American Chemical Society. 129: 5117-30. PMID 17397156 DOI: 10.1021/Ja068633M  0.554
2006 van der Wel PC, Hu KN, Lewandowski J, Griffin RG. Dynamic nuclear polarization of amyloidogenic peptide nanocrystals: GNNQQNY, a core segment of the yeast prion protein Sup35p. Journal of the American Chemical Society. 128: 10840-6. PMID 16910679 DOI: 10.1021/Ja0626685  0.542
2005 Pulay P, Scherer EM, van der Wel PC, Koeppe RE. Importance of tensor asymmetry for the analysis of 2H NMR spectra from deuterated aromatic rings. Journal of the American Chemical Society. 127: 17488-93. PMID 16332101 DOI: 10.1021/Ja054935X  0.517
2004 Strandberg E, Ozdirekcan S, Rijkers DT, van der Wel PC, Koeppe RE, Liskamp RM, Killian JA. Tilt angles of transmembrane model peptides in oriented and non-oriented lipid bilayers as determined by 2H solid-state NMR. Biophysical Journal. 86: 3709-21. PMID 15189867 DOI: 10.1529/Biophysj.103.035402  0.618
2003 Koeppe RE, Sun H, van der Wel PC, Scherer EM, Pulay P, Greathouse DV. Combined experimental/theoretical refinement of indole ring geometry using deuterium magnetic resonance and ab initio calculations. Journal of the American Chemical Society. 125: 12268-76. PMID 14519012 DOI: 10.1021/Ja035052D  0.548
2003 Weiss TM, van der Wel PC, Killian JA, Koeppe RE, Huang HW. Hydrophobic mismatch between helices and lipid bilayers. Biophysical Journal. 84: 379-85. PMID 12524291 DOI: 10.1016/S0006-3495(03)74858-9  0.623
2002 van der Wel PC, Strandberg E, Killian JA, Koeppe RE. Geometry and intrinsic tilt of a tryptophan-anchored transmembrane alpha-helix determined by (2)H NMR. Biophysical Journal. 83: 1479-88. PMID 12202373 DOI: 10.1016/S0006-3495(02)73918-0  0.622
2002 Strandberg E, Morein S, Rijkers DT, Liskamp RM, van der Wel PC, Killian JA. Lipid dependence of membrane anchoring properties and snorkeling behavior of aromatic and charged residues in transmembrane peptides. Biochemistry. 41: 7190-8. PMID 12044149 DOI: 10.1021/Bi012047I  0.37
2001 Greathouse DV, Goforth RL, Crawford T, Van Der Wel PC, Killian JA. Optimized aminolysis conditions for cleavage of N-protected hydrophobic peptides from solid-phase resins. The Journal of Peptide Research : Official Journal of the American Peptide Society. 57: 519-27. PMID 11437955 DOI: 10.1034/j.1399-3011.2001.00849.x  0.418
2000 van der Wel PC, Pott T, Morein S, Greathouse DV, Koeppe RE, Killian JA. Tryptophan-anchored transmembrane peptides promote formation of nonlamellar phases in phosphatidylethanolamine model membranes in a mismatch-dependent manner. Biochemistry. 39: 3124-33. PMID 10715134 DOI: 10.1021/Bi9922594  0.61
1999 Killian JA, Morein S, van der Wel PC, de Planque MR, Greathouse DV, Koeppe RE. Peptide influences on lipids. Novartis Foundation Symposium. 225: 170-83; discussion 1. PMID 10472055 DOI: 10.1002/9780470515716.Ch11  0.629
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