David B. Morton, Ph.D. - Publications

Affiliations: 
Integrative Bioscience Oregon Health and Science University, Portland, OR 
Area:
Drosophila neurobiology, cGMP signaling, ALS

58/178 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Lembke KM, Law AD, Ahrar J, Morton DB. Deletion of a specific exon in the voltage-gated calcium channel, , causes disrupted locomotion in Drosophila larvae. The Journal of Experimental Biology. PMID 30397173 DOI: 10.1242/jeb.191106  0.76
2017 Lembke KM, Morton DB. Exploring the Interaction of Drosophila TDP-43 and the Type II Voltage-Gated Calcium Channel, Cacophony, in Regulating Motor Function and Behavior. Journal of Experimental Neuroscience. 11: 1179069517740892. PMID 29162978 DOI: 10.1177/1179069517740892  0.76
2017 Lembke KM, Scudder C, Morton DB. Restoration of motor defects caused by loss of Drosophila TDP-43 by expression of the voltage-gated calcium channel, Cacophony, in central neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28847811 DOI: 10.1523/JNEUROSCI.0554-17.2017  0.76
2017 Chang JC, Morton DB. Drosophila lines with mutant and wild type human TDP-43 replacing the endogenous gene reveals phosphorylation and ubiquitination in mutant lines in the absence of viability or lifespan defects. Plos One. 12: e0180828. PMID 28686708 DOI: 10.1371/journal.pone.0180828  0.84
2015 Vanderwerf SM, Buck DC, Wilmarth PA, Sears LM, David LL, Morton DB, Neve KA. Role for Rab10 in Methamphetamine-Induced Behavior. Plos One. 10: e0136167. PMID 26291453 DOI: 10.1371/journal.pone.0136167  1
2014 Chang JC, Hazelett DJ, Stewart JA, Morton DB. Motor neuron expression of the voltage-gated calcium channel cacophony restores locomotion defects in a Drosophila, TDP-43 loss of function model of ALS. Brain Research. 1584: 39-51. PMID 24275199 DOI: 10.1016/j.brainres.2013.11.019  1
2013 Brown KM, Day JP, Huston E, Zimmermann B, Hampel K, Christian F, Romano D, Terhzaz S, Lee LC, Willis MJ, Morton DB, Beavo JA, Shimizu-Albergine M, Davies SA, Kolch W, et al. Phosphodiesterase-8A binds to and regulates Raf-1 kinase. Proceedings of the National Academy of Sciences of the United States of America. 110: E1533-42. PMID 23509299 DOI: 10.1073/pnas.1303004110  1
2012 Hazelett DJ, Chang JC, Lakeland DL, Morton DB. Comparison of parallel high-throughput RNA sequencing between knockout of TDP-43 and its overexpression reveals primarily nonreciprocal and nonoverlapping gene expression changes in the central nervous system of Drosophila. G3 (Bethesda, Md.). 2: 789-802. PMID 22870402 DOI: 10.1534/g3.112.002998  1
2011 Vermehren-Schmaedick A, Scudder C, Timmermans W, Morton DB. Drosophila gustatory preference behaviors require the atypical soluble guanylyl cyclases. Journal of Comparative Physiology. a, Neuroethology, Sensory, Neural, and Behavioral Physiology. 197: 717-27. PMID 21350862 DOI: 10.1007/s00359-011-0634-9  1
2011 Morton DB. Behavioral responses to hypoxia and hyperoxia in Drosophila larvae: molecular and neuronal sensors. Fly. 5: 119-25. PMID 21150317 DOI: 10.4161/fly.5.2.14284  1
2011 Saha D, Morton D, Ariel M, Wessel R. Response properties of visual neurons in the turtle nucleus isthmi. Journal of Comparative Physiology. a, Neuroethology, Sensory, Neural, and Behavioral Physiology. 197: 153-65. PMID 20967450 DOI: 10.1007/s00359-010-0596-3  1
2010 Vermehren-Schmaedick A, Ainsley JA, Johnson WA, Davies SA, Morton DB. Behavioral responses to hypoxia in Drosophila larvae are mediated by atypical soluble guanylyl cyclases. Genetics. 186: 183-96. PMID 20592263 DOI: 10.1534/genetics.110.118166  1
2010 Morton DB, Clemens-Grisham R, Hazelett DJ, Vermehren-Schmaedick A. Infertility and male mating behavior deficits associated with Pde1c in Drosophila melanogaster. Genetics. 186: 159-65. PMID 20551439 DOI: 10.1534/genetics.110.118018  1
2009 Zimmer M, Gray JM, Pokala N, Chang AJ, Karow DS, Marletta MA, Hudson ML, Morton DB, Chronis N, Bargmann CI. Neurons detect increases and decreases in oxygen levels using distinct guanylate cyclases. Neuron. 61: 865-79. PMID 19323996 DOI: 10.1016/j.neuron.2009.02.013  1
2008 Morton DB, Stewart JA, Langlais KK, Clemens-Grisham RA, Vermehren A. Synaptic transmission in neurons that express the Drosophila atypical soluble guanylyl cyclases, Gyc-89Da and Gyc-89Db, is necessary for the successful completion of larval and adult ecdysis. The Journal of Experimental Biology. 211: 1645-56. PMID 18456892 DOI: 10.1242/jeb.014472  1
2007 Morton DB, Vermehren A. Soluble Guanylyl Cyclases in Invertebrates: Targets for NO and O(2). Advances in Experimental Biology. 1: 65-82. PMID 19122779 DOI: 10.1016/S1872-2423(07)01003-4  1
2006 Vermehren A, Langlais KK, Morton DB. Oxygen-sensitive guanylyl cyclases in insects and their potential roles in oxygen detection and in feeding behaviors. Journal of Insect Physiology. 52: 340-8. PMID 16427074 DOI: 10.1016/j.jinsphys.2005.12.001  1
2005 Morton DB, Langlais KK, Stewart JA, Vermehren A. Comparison of the properties of the five soluble guanylyl cyclase subunits in Drosophila melanogaster. Journal of Insect Science (Online). 5: 12. PMID 16341244  1
2004 Morton DB. Atypical soluble guanylyl cyclases in Drosophila can function as molecular oxygen sensors. The Journal of Biological Chemistry. 279: 50651-3. PMID 15485853 DOI: 10.1074/jbc.C400461200  1
2004 Langlais KK, Stewart JA, Morton DB. Preliminary characterization of two atypical soluble guanylyl cyclases in the central and peripheral nervous system of Drosophila melanogaster. The Journal of Experimental Biology. 207: 2323-38. PMID 15159437 DOI: 10.1242/jeb.01025  1
2004 Morton DB. Invertebrates yield a plethora of atypical guanylyl cyclases. Molecular Neurobiology. 29: 97-116. PMID 15126679 DOI: 10.1385/MN:29:2:097  1
2003 Morton DB, Anderson EJ. MsGC-beta3 forms active homodimers and inactive heterodimers with NO-sensitive soluble guanylyl cyclase subunits. The Journal of Experimental Biology. 206: 937-47. PMID 12582136 DOI: 10.1242/jeb.00160  1
2003 Morton DB, Nighorn A. MsGC-II, a receptor guanylyl cyclase isolated from the CNS of Manduca sexta that is inhibited by calcium. Journal of Neurochemistry. 84: 363-72. PMID 12558998 DOI: 10.1046/j.1471-4159.2003.01528.x  1
2002 Morton DB, Simpson PJ. Cellular signaling in eclosion hormone action. Journal of Insect Physiology. 48: 1-13. PMID 12770127 DOI: 10.1016/S0022-1910(01)00157-3  1
2002 Zayas RM, Qazi S, Morton DB, Trimmer BA. Nicotinic-acetylcholine receptors are functionally coupled to the nitric oxide/cGMP-pathway in insect neurons. Journal of Neurochemistry. 83: 421-31. PMID 12423252 DOI: 10.1046/j.1471-4159.2002.01147.x  1
2002 Morton DB, Hudson ML. Cyclic GMP regulation and function in insects Advances in Insect Physiology. 29: 1-54.  1
2001 Nighorn A, Simpson PJ, Morton DB. The novel guanylyl cyclase MsGC-I is strongly expressed in higher-order neuropils in the brain of Manduca sexta. The Journal of Experimental Biology. 204: 305-14. PMID 11136616  1
2000 Hesterlee S, Morton DB. Identification of the cellular target for eclosion hormone in the abdominal transverse nerves of the tobacco hornworm, Manduca sexta. The Journal of Comparative Neurology. 424: 339-55. PMID 10906707 DOI: 10.1002/1096-9861(20000821)424:2<339::AID-CNE11>3.0.CO;2-Z  1
2000 Zayas RM, Qazi S, Morton DB, Trimmer BA. Neurons involved in nitric oxide-mediated cGMP signaling in the tobacco hornworm, Manduca sexta. The Journal of Comparative Neurology. 419: 422-38. PMID 10742713 DOI: 10.1002/(SICI)1096-9861(20000417)419:4<422::AID-CNE2>3.0.CO;2-S  1
1999 Morton DB, Hudson ML, Waters E, O'Shea M. Soluble guanylyl cyclases in Caenorhabditis elegans: NO is not the answer. Current Biology : Cb. 9: R546-7. PMID 10469574 DOI: 10.1016/S0960-9822(99)80349-2  1
1999 Simpson PJ, Nighorn A, Morton DB. Identification of a novel guanylyl cyclase that is related to receptor guanylyl cyclases, but lacks extracellular and transmembrane domains. The Journal of Biological Chemistry. 274: 4440-6. PMID 9933648 DOI: 10.1074/jbc.274.7.4440  1
1999 Nighorn A, Byrnes KA, Morton DB. Identification and characterization of a novel beta subunit of soluble guanylyl cyclase that is active in the absence of a second subunit and is relatively insensitive to nitric oxide. The Journal of Biological Chemistry. 274: 2525-31. PMID 9891024 DOI: 10.1074/jbc.274.4.2525  1
1998 Nighorn A, Gibson NJ, Rivers DM, Hildebrand JG, Morton DB. The nitric oxide-cGMP pathway may mediate communication between sensory afferents and projection neurons in the antennal lobe of Manduca sexta. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 7244-55. PMID 9736646  1
1998 Morton DB, Bredt DS. Norepinephrine increases cyclic GMP levels in cerebellar cells from neuronal nitric oxide synthase knockout mice. Journal of Neurochemistry. 71: 440-3. PMID 9648894  1
1997 Morton DB. Eclosion hormone action on the nervous system. Intracellular messengers and sites of action. Annals of the New York Academy of Sciences. 814: 40-50. PMID 9160958 DOI: 10.1111/j.1749-6632.1997.tb46143.x  1
1997 Mészáros M, Morton DB. Up- and downregulation of esr20, an ecdysteroid-regulated gene expressed in the tracheae of Manduca sexta. Archives of Insect Biochemistry and Physiology. 34: 159-74. PMID 9041697 DOI: 10.1002/(SICI)1520-6327(1997)34:2<159::AID-ARCH3>3.0.CO;2-S  1
1996 Morton DB. Neuropeptide-stimulated cyclic guanosine monophosphate immunoreactivity in the neurosecretory terminals of a neurohemal organ. Journal of Neurobiology. 29: 341-53. PMID 8907163 DOI: 10.1002/(SICI)1097-4695(199603)29:3<341::AID-NEU6>3.0.CO;2-9  1
1996 Mészáros M, Morton DB. Expression of a developmentally regulated gene, Mng10, in identified neurosecretory cells in the CNS of Manduca sexta. Journal of Neurobiology. 30: 349-58. PMID 8807528 DOI: 10.1002/(SICI)1097-4695(199607)30:3<349::AID-NEU4>3.0.CO;2-4  1
1996 Hesterlee S, Morton DB. Insect physiology: the emerging story of ecdysis. Current Biology : Cb. 6: 648-50. PMID 8793284  1
1996 Mészáros M, Morton DB. Comparison of the expression patterns of five developmentally regulated genes in Manduca sexta and their regulation by 20-hydroxyecdysone in vitro. The Journal of Experimental Biology. 199: 1555-61. PMID 8699157  1
1996 Mészáros M, Morton DB. Subtractive hybridization strategy using paramagnetic oligo(dT) beads and PCR. Biotechniques. 20: 413-9. PMID 8679200  1
1996 Mészáros M, Morton DB. Identification of a developmentally regulated gene, esr16, in the tracheal epithelium of Manduca sexta, with homology to a protein from human epididymis. Insect Biochemistry and Molecular Biology. 26: 7-11. PMID 8673080  1
1995 Morton DB, Truman JW. Effect of cycloheximide on eclosion hormone sensitivity and the developmental appearance of the eclosion hormone and cGMP regulated phosphoproteins in the CNS of the tobacco hornworm, Manduca sexta. Journal of Receptor and Signal Transduction Research. 15: 773-86. PMID 8747886 DOI: 10.3109/10799899509079906  1
1995 Morton DB, Simpson PJ. Eclosion hormone-stimulated cGMP levels in the central nervous system of Manduca sexta: inhibition by lipid metabolism blockers, increase in inositol(1,4,5)trisphosphate and further evidence against the involvement of nitric oxide. Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology. 165: 417-27. PMID 8576454 DOI: 10.1007/BF00261295  1
1995 Levine RB, Morton DB, Restifo LL. Remodeling of the insect nervous system. Current Opinion in Neurobiology. 5: 28-35. PMID 7773002 DOI: 10.1016/0959-4388(95)80083-2  1
1994 Mészáros M, Morton DB. Isolation and partial characterization of a gene from trachea of Manduca sexta that requires and is negatively regulated by ecdysteroids. Developmental Biology. 162: 618-30. PMID 8150220 DOI: 10.1006/dbio.1994.1115  1
1994 Krull CE, Morton DB, Faissner A, Schachner M, Tolbert LP. Spatiotemporal pattern of expression of tenascin-like molecules in a developing insect olfactory system. Journal of Neurobiology. 25: 515-34. PMID 7520933 DOI: 10.1002/neu.480250506  1
1992 Morton DB, Giunta MA. Eclosion hormone stimulates cyclic GMP levels in Manduca sexta nervous tissue via arachidonic acid metabolism with little or no contribution from the production of nitric oxide. Journal of Neurochemistry. 59: 1522-30. PMID 1357096  1
1991 Eldridge R, Horodyski FM, Morton DB, O'Reilly DR, Truman JW, Riddiford LM, Miller LK. Expression of an eclosion hormone gene in insect cells using baculovirus vectors Insect Biochemistry. 21: 341-351. DOI: 10.1016/0020-1790(91)90025-A  1
1990 Truman JW, Morton DB. The eclosion hormone system: an example of coordination of endocrine activity during the molting cycle of insects. Progress in Clinical and Biological Research. 342: 300-8. PMID 2200008  1
1988 Morton DB, Truman JW. The EGPs: the eclosion hormone and cyclic GMP-regulated phosphoproteins. II. Regulation of appearance by the steroid hormone 20-hydroxyecdysone in Manduca sexta. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 1338-45. PMID 2833583  1
1988 Morton DB, Truman JW. The EGPs: the eclosion hormone and cyclic GMP-regulated phosphoproteins. I. Appearance and partial characterization in the CNS of Manduca sexta. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 1326-37. PMID 2833582  1
1986 Morton DB, Truman JW. Substrate phosphoprotein availability regulates eclosion hormone sensitivity in an insect CNS. Nature. 323: 264-7. PMID 3020427 DOI: 10.1038/323264a0  1
1985 Morton DB, Truman JW. Steroid regulation of the peptide-mediated increase in cyclic GMP in the nervous system of the hawkmoth, Manduca sexta. Journal of Comparative Physiology. a, Sensory, Neural, and Behavioral Physiology. 157: 423-32. PMID 2426446 DOI: 10.1007/BF00615142  1
1985 Davenport AP, Morton DB, Evans PD. The action of formamidines on octopamine receptors in the locust Pesticide Biochemistry and Physiology. 24: 45-52. DOI: 10.1016/0048-3575(85)90112-9  1
1984 Morton DB. Pharmacology of the octopamine-stimulated adenylate cyclase of the locust and tick CNS. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology. 78: 153-8. PMID 6146464 DOI: 10.1016/0742-8413(84)90063-X  1
1984 Morton DB, Evans PD. Octopamine release from an identified neurone in the locust Journal of Experimental Biology. 269-287.  1
1983 Morton DB, Evans PD. Octopamine distribution in solitarious and gregarious forms of the locust, Schistocerca Americana gregaria Insect Biochemistry. 13: 177-183. DOI: 10.1016/0020-1790(83)90081-1  1
Low-probability matches
2019 Xie B, Morton DB, Cook TA. Opposing transcriptional and post-transcriptional roles for scalloped in binary hippo-dependent neural fate decisions. Developmental Biology. PMID 31265830 DOI: 10.1016/j.ydbio.2019.06.022  0.12
2014 Part CE, Kiddie JL, Hayes WA, Mills DS, Neville RF, Morton DB, Collins LM. Physiological, physical and behavioural changes in dogs (Canis familiaris) when kennelled: testing the validity of stress parameters. Physiology & Behavior. 133: 260-71. PMID 24866912 DOI: 10.1016/j.physbeh.2014.05.018  0.08
2013 Morton DB. Environmental refinement and quality of life. Veterinary Journal (London, England : 1997). 195: 4-5. PMID 23261762 DOI: 10.1016/j.tvjl.2012.11.007  0.08
2012 Morton DB. A risk assessment approach to severity classification in animal research. Alternatives to Laboratory Animals : Atla. 40: P2-3. PMID 23215667  0.08
2011 Hawkins P, Morton DB, Burman O, Dennison N, Honess P, Jennings M, Lane S, Middleton V, Roughan JV, Wells S, Westwood K. A guide to defining and implementing protocols for the welfare assessment of laboratory animals: eleventh report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement. Laboratory Animals. 45: 1-13. PMID 21123303 DOI: 10.1258/la.2010.010031  0.08
2010 Jennings M, Morton DB, Charton E, Cooper J, Hendriksen C, Martin S, Pearce MC, Price S, Redhead K, Reed N, Simmons H, Spencer S, Willingale H. Application of the Three Rs to challenge assays used in vaccine testing: tenth report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement. Biologicals : Journal of the International Association of Biological Standardization. 38: 684-95. PMID 20724180 DOI: 10.1016/j.biologicals.2010.04.004  0.08
2010 Morton DB. A commentary on the animal welfare symposium, with possible actions. Journal of Veterinary Medical Education. 37: 107-13. PMID 20378888 DOI: 10.3138/jvme.37.1.107  0.08
2009 Jennings M, Prescott MJ, Buchanan-Smith HM, Gamble MR, Gore M, Hawkins P, Hubrecht R, Hudson S, Jennings M, Keeley JR, Morris K, Morton DB, Owen S, Pearce PC, et al. Refinements in husbandry, care and common procedures for non-human primates: Ninth report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement. Laboratory Animals. 43: 1-47. PMID 19286892 DOI: 10.1258/la.2008.007143  0.08
2007 Morton DB. Vaccines and animal welfare. Revue Scientifique Et Technique (International Office of Epizootics). 26: 157-63. PMID 17633300  0.08
2007 Morton DB. A hypothetical strategy for the objective evaluation of animal well-being and quality of life using a dog model Animal Welfare. 16: 75-81.  0.08
2006 Wells DJ, Playle LC, Enser WE, Flecknell PA, Gardiner MA, Holland J, Howard BR, Hubrecht R, Humphreys KR, Jackson IJ, Lane N, Maconochie M, Mason G, Morton DB, Raymond R, et al. Assessing the welfare of genetically altered mice. Laboratory Animals. 40: 111-4. PMID 16600070 DOI: 10.1258/002367706776318971  0.08
2006 Prunier A, Bonneau M, von Borell EH, Cinotti S, Gunn M, Fredriksen B, Giersing M, Morton DB, Tuyttens FAM, Velarde A. A review of the welfare consequences of surgical castration in piglets and the evaluation of non-surgical methods Animal Welfare. 15: 277-289.  0.08
2005 Buchanan-Smith HM, Rennie AE, Vitale A, Pollo S, Prescott MJ, Morton DB. Harmonising the definition of refinement Animal Welfare. 14: 379-384.  0.08
2004 Carbone L, Baumans V, Morton DB. Report of the workshop on euthanasia guidelines and practices. Alternatives to Laboratory Animals : Atla. 32: 445-6. PMID 23581115  0.08
2004 Morton DB. The welfare of non-human primates in research in the EU. Alternatives to Laboratory Animals : Atla. 32: 307. PMID 23577478  0.08
2004 Raj AB, Leach MC, Morton DB. Carbon dioxide for euthanasia of laboratory animals. Comparative Medicine. 54: 470-1. PMID 15575359  0.08
2004 Prescott MJ, Morton DB, Anderson D, Buckwell A, Heath S, Hubrecht R, Jennings M, Robb D, Ruane B, Swallow J, Thompson P. Refining dog husbandry and care: Eighth report of the BVAAWF/FRAME/RSPCA/ UFAW Joint Working Group on Refinement Laboratory Animals. 38: S1:1-S1:94. PMID 15202954  0.08
2004 Hawkins P, Morton DB, Bevan R, Heath K, Kirkwood J, Pearce P, Scott L, Whelan G, Webb A. Husbandry refinements for rats, mice, dogs and non-human primates used in telemetry procedures. Seventh report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement, Part B. Laboratory Animals. 38: 1-10. PMID 14979982 DOI: 10.1258/00236770460734335  0.08
2004 Morton DB. What value has life over quality of life? Lab Animal. 33: 17-18. DOI: 10.1038/laban0704-17c  0.08
2004 Leach MC, Bowell VA, Allan TF, Morton DB. Measurement of aversion to determine humane methods of anaesthesia and euthanasia Animal Welfare. 13: S77-S86.  0.08
2003 Morton DB, Hawkins P, Bevan R, Heath K, Kirkwood J, Pearce P, Scott L, Whelan G, Webb A. Refinements in telemetry procedures. Seventh report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement, Part A. Laboratory Animals. 37: 261-99. PMID 14599304 DOI: 10.1258/002367703322389861  0.08
2003 Robinson V, Morton DB, Anderson D, Carver JFA, Francis RJ, Hubrecht R, Jenkins E, Mathers KE, Raymond R, Rosewell I, Wallace J, Wells DJ. Refinement and reduction in production of genetically modified mice Laboratory Animals. 37: i-iv+1-51. PMID 12886901  0.08
2003 Johannes S, Hartinger J, Hendriksen CF, Morton DB, Cussler K. Humane endpoints in the efficacy testing of swine erysipelas vaccines. Altex. 20: 11-5. PMID 12579350  0.08
2002 Morton DB, Hanenberg E, Hogg A, Priebel Valera G, Lund C, Ottiger HP, Gorska P, Borensztejn C, Pereira S, Bousrih M, Blumrich M, Chapek ML, Ramirez A, Thuring J, Umiza A. Best animal care practices in the production and control of biologicals. Developments in Biologicals. 111: 221-5. PMID 12678246  0.08
2002 Leach MC, Bowell VA, Allan TF, Morton DB. Degrees of aversion shown by rats and mice to different concentrations of inhalational anaesthetics. The Veterinary Record. 150: 808-15. PMID 12120924  0.08
2002 Leach MC, Bowell VA, Allan TF, Morton DB. Aversion to gaseous euthanasia agents in rats and mice. Comparative Medicine. 52: 249-57. PMID 12102571  0.08
2001 Thornton PD, Morton DB, Main DC, Kirkwood JK, Wright B. Veterinary ethics: filling a gap in undergraduate education. The Veterinary Record. 148: 214-6. PMID 11266002  0.08
2001 Morton DB, Jennings M, Buckwell A, Ewbank R, Godfrey C, Holgate B, Inglis I, James R, Page C, Sharman I, Verschoyle R, Westall L, Wilson AB. Refining procedures for the administration of substances. Report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement. British Veterinary Association Animal Welfare Foundation/Fund for the Replacement of Animals in Medical Experiments/Royal Society for the Prevention of Cruelty to Animals/Universities Federation for Animal Welfare. Laboratory Animals. 35: 1-41. PMID 11201285 DOI: 10.1258/0023677011911345  0.08
2001 Hawkins P, Morton DB, Cameron D, Cuthill I, Francis R, Freire R, Gosler A, Healy S, Hudson A, Inglis I, Jones A, Kirkwood J, Lawton M, Monaghan P, Sherwin C, et al. Laboratory birds: Refinements in husbandry and procedures Laboratory Animals. 35: S12-S1163.  0.08
2000 Morton DB. A systematic approach for establishing humane endpoints. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 41: 80-6. PMID 11406701  0.08
2000 Morton DB. Self-consciousness and animal suffering. Biologist (London, England). 47: 77-80. PMID 11190233  0.08
2000 Sreeram N, Townsend P, Morton DB. Radiofrequency thermal balloon angioplasty in an experimental model of peripheral arterial stenosis. International Journal of Cardiology. 74: 25-32. PMID 10854677 DOI: 10.1016/S0167-5273(00)00241-2  0.08
2000 Morton DB. Introduction to the second annual frame lecture, by Dr Jon Richmond, presented at the royal society of medicine, London, on 31 October 2000 Atla Alternatives to Laboratory Animals. 28: 759.  0.08
1999 Morton DB. Refinement of in vivo tests. Developments in Biological Standardization. 101: 187-93. PMID 10566792  0.08
1998 Jennings M, Batchelor GR, Brain PF, Dick A, Elliott H, Francis RJ, Hubrecht RC, Hurst JL, Morton DB, Peters AG, Raymond R, Sales GD, Sherwin CM, West C. Refining rodent husbandry: the mouse. Report of the Rodent Refinement Working Party. Laboratory Animals. 32: 233-59. PMID 9718472  0.08
1998 Smaje LH, Smith JA, Combes RD, Ewbank R, Gregory JA, Jennings M, Moore GJ, Morton DB. Advancing refinement of laboratory animal use Laboratory Animals. 32: 137-142. PMID 9587895  0.08
1998 Morton DB. The Second International Symposium on Infection Models in Antimicrobial Chemotherapy, Reykjavik, July 1996: Ethical considerations in the use of animal models in infection Clinical Microbiology and Infection. 4: 613-614.  0.08
1997 Morton DB. Qualifications in animal welfare science, ethics and law. The Veterinary Record. 140: 435. PMID 9149367  0.08
1995 Balls M, Goldberg AM, Fentem JH, Broadhead CL, Burch RL, Festing MF, Frazier JM, Hendriksen CF, Jennings M, van der Kamp MD, Morton DB, Rowan AN, Russell C, Russell WM, Spielmann H, et al. The three Rs: the way forward: the report and recommendations of ECVAM Workshop 11. Alternatives to Laboratory Animals : Atla. 23: 838-66. PMID 11660368  0.08
1995 Morton DB. Advances in refinement in animal experimentation over the past 25 years. Alternatives to Laboratory Animals : Atla. 23: 812-22. PMID 11660365  0.08
1995 Morton DB. Docking and other practices. The Veterinary Record. 137: 103. PMID 8533242  0.08
1995 Tuli JS, Smith JA, Morton DB. Effects of acute and chronic restraint on the adrenal gland weight and serum corticosterone concentration of mice and their faecal output of oocysts after infection with Eimeria apionodes. Research in Veterinary Science. 59: 82-6. PMID 8525092 DOI: 10.1016/0034-5288(95)90036-5  0.08
1995 Morton DB. Docking of puppies' tails. The Veterinary Record. 136: 274. PMID 7793025  0.08
1995 Morton DB. Ethics of farm animal exports. The Veterinary Record. 136: 252. PMID 7785185  0.08
1995 Tuli JS, Smith JA, Morton DB. Corticosterone, adrenal and spleen weight in mice after tail bleeding, and its effect on nearby animals. Laboratory Animals. 29: 90-5. PMID 7707684  0.08
1995 Tuli JS, Smith JA, Morton DB. Stress measurements in mice after transportation. Laboratory Animals. 29: 132-8. PMID 7602999  0.08
1995 Gunn D, Morton DB. Inventory of the behaviour of New Zealand White rabbits in laboratory cages Applied Animal Behaviour Science. 45: 277-292. DOI: 10.1016/0168-1591(95)00627-5  0.08
1994 Thompson DJ, Manser CE, Morton DB, Turnbull AT, Winter AC. Postgraduate qualifications in animal welfare. The Veterinary Record. 134: 199. PMID 8171800  0.08
1994 Evans GO, Morton DB, Jennings M. Removal of blood from laboratory mammals and birds [1] Laboratory Animals. 28: 178-179. PMID 8035571  0.08
1994 Morton DB. Commentaries on this month's cardiovascular controversy: The merits and demerits of animal experimentation from D B Morton Cardiovascular Research. 28: 1112-1113. DOI: 10.1093/cvrese/28.7.1112  0.08
1993 Morton DB, Jennings M, Batchelor GR, Bell D, Birke L, Davies K, Eveleigh JR, Gunn D, Heath M, Howard B, Koder P, Phillips J, Poole T, Sainsbury AW, Sales GD, et al. Refinements in rabbit husbandry: Second report of the BVAAWF/FRAME/RSPCA/UFAW Joint Working Group on Refinement Laboratory Animals. 27: 301-329. PMID 8277705  0.08
1993 Morton DB. Is unnecessary suffering avoidable? The Veterinary Record. 133: 304. PMID 8236663  0.08
1993 Fielder RJ, Allen JA, Boobis AR, Botham PA, Doe J, Esdaile DJ, Gatehouse DG, Hodson-Walker G, Morton DB, Kirkland DJ, Richold M. Report of the BTS/UKEMS working group on dose setting in In-Vivo mutagenicity assays Human and Experimental Toxicology. 12: 189-198.  0.08
1992 Soothill JS, Morton DB, Ahmad A. The HID50 (hypothermia-inducing dose 50): an alternative to the LD50 for measurement of bacterial virulence. International Journal of Experimental Pathology. 73: 95-8. PMID 1576081  0.08
1992 Simpson KW, Johnstone JM, Bell PR, Morton DB, Batt RM. Pancreatic function following partial pancreatectomy and anastomosis of the pancreatic duct to the stomach or duodenum in dogs. Research in Veterinary Science. 52: 97-104. PMID 1553443 DOI: 10.1016/0034-5288(92)90065-A  0.08
1992 Fielder RJ, Allen JA, Boobis AR, Botham PA, Doe J, Esdaile DJ, Gatehouse DG, Hodson-Walker G, Morton DB, Kirkland DJ. Report of British Toxicology Society/UK Environmental Mutagen Society Working Group. Dose setting in in vivo mutagenicity assays. Mutagenesis. 7: 313-9. PMID 1470025 DOI: 10.1093/mutage/7.5.313  0.08
1991 Flecknell PA, Morton DB. Use of animals in research. The Veterinary Record. 128: 531. PMID 1866886  0.08
1991 Simpson KW, Simpson JW, Lake S, Morton DB, Batt RM. Effect of pancreatectomy on plasma activities of amylase, isoamylase, lipase and trypsin-like immunoreactivity in dogs. Research in Veterinary Science. 51: 78-82. PMID 1716775 DOI: 10.1016/0034-5288(91)90035-M  0.08
1990 Morton DB, Berghardt GM, Smith JA. Animals, science, and ethics -- Section III. Critical anthropomorphism, animal suffering, and the ecological context. The Hastings Center Report. 20: S13-9. PMID 11650362  0.08
1990 Morton DB. Attacks on veterinary surgeons. The Veterinary Record. 126: 628. PMID 2378050  0.08
1990 Morton DB. Homoeopathy. The Veterinary Record. 126: 488. PMID 2349768  0.08
1990 Simpson KW, Batt RM, Jones D, Morton DB. Effects of exocrine pancreatic insufficiency and replacement therapy on the bacterial flora of the duodenum in dogs. American Journal of Veterinary Research. 51: 203-6. PMID 2301831  0.08
1990 Morton DB. The Animals (Scientific Procedures) Act 1986 and research into anaesthesia. British Journal of Anaesthesia. 65: 303-5. PMID 2223357  0.08
1990 Morton DB. Guidelines on the recognition on pain, distress and discomfort in experimental animals European Journal of Pharmacology. 183: 1583.  0.08
1989 Batt RM, Horadagoda NU, McLean L, Morton DB, Simpson KW. Identification and characterization of a pancreatic intrinsic factor in the dog. The American Journal of Physiology. 256: G517-23. PMID 2923213  0.08
1989 Simpson KW, Morton DB, Batt RM. Effect of exocrine pancreatic insufficiency on cobalamin absorption in dogs. American Journal of Veterinary Research. 50: 1233-6. PMID 2782706  0.08
1989 Morton DB. Strychnine poisoning. The Veterinary Record. 124: 409. PMID 2728287  0.08
1989 Morton DB, Bruce SG. Semen evaluation, cryopreservation and factors relevant to the use of frozen semen in dogs. Journal of Reproduction and Fertility. Supplement. 39: 311-6. PMID 2695641  0.08
1989 Simpson KW, Morton DB, Sørensen SH, McLean L, Riley JE, Batt RM. Biochemical changes in the jejunal mucosa of dogs with exocrine pancreatic insufficiency following pancreatic duct ligation. Research in Veterinary Science. 47: 338-45. PMID 2595094  0.08
1989 Brittain GP, Rostron CK, Morton DB, Rees JE. The use of a biological adhesive to achieve sutureless epikeratophakia. Eye (London, England). 3: 56-63. PMID 2591599 DOI: 10.1038/eye.1989.8  0.08
1989 Samani NJ, Swales JD, Jeffreys AJ, Morton DB, Naftilan AJ, Lindpaintner K, Ganten D, Brammar WJ. DNA fingerprinting of spontaneously hypertensive and Wistar-Kyoto rats: implications for hypertension research. Journal of Hypertension. 7: 809-16. PMID 2584697 DOI: 10.1097/00004872-198910000-00006  0.08
1989 Simpson KW, Batt RM, McLean L, Morton DB. Circulating concentrations of trypsin-like immunoreactivity and activities of lipase and amylase after pancreatic duct ligation in dogs. American Journal of Veterinary Research. 50: 629-32. PMID 2471426  0.08
1989 Morton DB. Use of animals in research [2] Nature. 340: 10.  0.08
1988 Rostron CK, Sandford-Smith JH, Morton DB. Experimental epikeratophakia using tissue lathed at room temperature. The British Journal of Ophthalmology. 72: 354-60. PMID 3293653  0.08
1988 Leese T, West KP, Morton DB, Bell PR. Fresh frozen plasma therapy in acute pancreatitis: an experimental study. International Journal of Pancreatology : Official Journal of the International Association of Pancreatology. 3: 437-47. PMID 3221106 DOI: 10.1007/BF02788202  0.08
1988 Rostron CK, Brittain GP, Morton DB, Rees JE. Experimental epikeratophakia with biological adhesive. Archives of Ophthalmology (Chicago, Ill. : 1960). 106: 1103-6. PMID 2456752 DOI: 10.1001/archopht.1988.01060140259037  0.08
1988 Leese T, Husken PA, Morton DB. Buprenorphine analgesia in a rat model of acute pancreatitis Surgical Research Communications. 3: 53-60.  0.08
1988 Johnstone JMS, Simpson KW, Bell PRF, Morton DB. A comparison of draining the tail of the pancreas into the duodenum or stomach in dogs after partial pancreatectomy Surgical Research Communications. 2: 263-269.  0.08
1988 Morton DB. The main provisions of the animals (Scientific Procedures) Act 1986 Laboratory Animal Science. 38: 27-35.  0.08
1987 Jeffreys AJ, Morton DB. DNA fingerprints of dogs and cats. Animal Genetics. 18: 1-15. PMID 2886082  0.08
1987 Morton DB, Yaxley RE, Patel I, Jeffreys AJ, Howes SJ, Debenham PG. Use of DNA fingerprint analysis in identification of the sire. The Veterinary Record. 121: 592-4. PMID 2830701  0.08
1986 Morton DB. Assessment of pain. The Veterinary Record. 119: 435. PMID 3788006  0.08
1986 Baker AR, Evans DH, Prytherch DR, Morton DB, Bentley S, Asher MJ, Bell PR. Some failings of pulsatility index and damping factor. Ultrasound in Medicine & Biology. 12: 875-81. PMID 2949414 DOI: 10.1016/0301-5629(86)90005-0  0.08
1985 Morton DB. Pain and laboratory animals. Nature. 317: 106. PMID 4033793 DOI: 10.1038/317106a0  0.08
1985 Morton DB, Griffiths PH. Guidelines on the recognition of pain, distress and discomfort in experimental animals and an hypothesis for assessment. The Veterinary Record. 116: 431-6. PMID 3923690  0.08
2020 De Briyne N, Vidović J, Morton DB, Magalhães-Sant'Ana M. Evolution of the Teaching of Animal Welfare Science, Ethics and Law in European Veterinary Schools (2012-2019). Animals : An Open Access Journal From Mdpi. 10. PMID 32708281 DOI: 10.3390/ani10071238  0.01
2020 Morton DB. Ethics and animal research. The Veterinary Record. 186: 356. PMID 32198257 DOI: 10.1136/vr.m1081  0.01
2017 Magalhães-Sant'Ana M, More SJ, Morton DB, Hanlon AJ. Challenges facing the veterinary profession in Ireland: 2. On-farm use of veterinary antimicrobials. Irish Veterinary Journal. 70: 28. PMID 28932389 DOI: 10.1186/s13620-017-0106-9  0.01
2017 Magalhães-Sant'Ana M, More SJ, Morton DB, Hanlon AJ. Challenges facing the veterinary profession in Ireland: 3. emergency and casualty slaughter certification. Irish Veterinary Journal. 70: 24. PMID 28785400 DOI: 10.1186/s13620-017-0102-0  0.01
2017 Magalhães-Sant'Ana M, More SJ, Morton DB, Hanlon AJ. Challenges facing the veterinary profession in Ireland: 1. clinical veterinary services. Irish Veterinary Journal. 70: 17. PMID 28593042 DOI: 10.1186/s13620-017-0096-7  0.01
2016 Morton DB. Animal suffering and expert evidence. The Veterinary Record. 179: 305-6. PMID 27660355 DOI: 10.1136/vr.i4970  0.01
2016 Kanost MR, Arrese EL, Cao X, Chen YR, Chellapilla S, Goldsmith MR, Grosse-Wilde E, Heckel DG, Herndon N, Jiang H, Papanicolaou A, Qu J, Soulages JL, Vogel H, Walters J, ... ... Morton DB, et al. Multifaceted biological insights from a draft genome sequence of the tobacco hornworm moth, Manduca sexta. Insect Biochemistry and Molecular Biology. PMID 27522922 DOI: 10.1016/j.ibmb.2016.07.005  0.01
2015 Beauchamp TL, Morton DB. The Upper Limits of Pain and Suffering in Animal Research. Cambridge Quarterly of Healthcare Ethics : Cq : the International Journal of Healthcare Ethics Committees. 24: 431-47. PMID 26364778 DOI: 10.1017/S0963180115000092  0.01
2015 Magalhães-Sant'Ana M, More SJ, Morton DB, Osborne M, Hanlon A. What do European veterinary codes of conduct actually say and mean? A case study approach. The Veterinary Record. 176: 654. PMID 25861823 DOI: 10.1136/vr.103005  0.01
2014 Morton DB. Integration of UAS for law enforcement Auvsi Unmanned Systems 2014. 1: 457-488.  0.01
2000 Morton DB. Hunting inquiry. The Veterinary Record. 147: 83. PMID 10958497  0.01
2000 Morton DB. Decisions on euthanasia. The Veterinary Record. 147: 116. PMID 10955887  0.01
1999 Orlans FB, Beauchamp TL, Dresser R, Morton DB, Gluck JP. Animal rights review [2] Science. 283: 938.  0.01
1998 Morton DB. Ethical considerations in the use of animal models in infection. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 4: 613-614. PMID 11864257  0.01
1995 Townsend P, Morton DB. Laboratory Animal Care Policies and Regulations: United Kingdom. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 37: 68-74. PMID 11528027  0.01
1988 Dando PM, Morton DB, Buttle DJ, Barrett AJ. Quantitative assessment of human proteinases as agents for chemonucleolysis. Spine. 13: 188-92. PMID 3043717  0.01
1987 Morton DB, Dunphy GB, Chadwick JS. Reactions of hemocytes of immune and non-immune Galleria mellonella larvae to Proteus mirabilis. Developmental and Comparative Immunology. 11: 47-55. PMID 3109970 DOI: 10.1016/0145-305X(87)90007-3  0.01
1986 Dunphy GB, Morton DB, Chadwick JM. Pathogenicity of lipopolysaccharide mutants of Pseudomonas aeruginosa for larvae of Galleria mellonella: Hemocyte interaction with the bacteria Journal of Invertebrate Pathology. 47: 56-64. DOI: 10.1016/0022-2011(86)90163-1  0.01
1986 Dunphy GB, Morton DB, Kropinski A, Chadwick JM. Pathogenicity of lipopolysaccharide mutants of Pseudomonas aeruginosa for larvae of Galleria mellonella: Bacterial properties associated with virulence Journal of Invertebrate Pathology. 47: 48-55. DOI: 10.1016/0022-2011(86)90162-X  0.01
1985 Khalil MN, Thornback J, Early MY, Morton DB, Berry JM, Hubner PJ. Technetium-99m isonitrile complex as a potential myocardial imaging agent. Nuclear Medicine Communications. 6: 615-22. PMID 3841387  0.01
1984 Morton DB, Barnett RI, Chadwick JS. Structural alterations to Proteus mirabilis as a result of exposure to haemolymph from the larvae of Galleria mellonella. Microbios. 39: 177-85. PMID 6374385  0.01
1980 Morton DB, McCarthy LR. Bartholinitis-an unusual etiologic agent Obstetrics and Gynecology. 55: 97S-98S. PMID 7360461  0.01
1979 Morton DB, Curry VA, Harkiss GD. The effect on fertility of vaccinating female sheep with biochemically defined fractions of ram spermatozoa. Fertility and Sterility. 31: 683-6. PMID 446794  0.01
1979 Morton DB, McAnulty PA. The effect on fertility of immunizing female sheep with ram sperm acrosin and hyaluronidase. Journal of Reproductive Immunology. 1: 61-73. PMID 399489 DOI: 10.1016/0165-0378(79)90030-5  0.01
1978 McAnulty PA, Morton DB. The immune response of the genital tract of the female rabbit following systemic and local immunization. Journal of Clinical & Laboratory Immunology. 1: 255-60. PMID 756472  0.01
1976 Morton DB. Lysosomal enzymes in mammalian spermatozoa. Frontiers of Biology. 45: 203-55. PMID 185098  0.01
1975 Morton DB. Acrosomal enzymes: Immunochemical localization of acrosin and hyaluronidase in ram spermatozoa. Journal of Reproduction and Fertility. 45: 375-8. PMID 1107535  0.01
1974 Morton DB, Glover TD. Sperm transport in the female rabbit: the effect of inseminate volume and sperm density. Journal of Reproduction and Fertility. 38: 139-46. PMID 4841386  0.01
1974 Morton DB, Fitzpatrick RJ. The effect of oxytocin on sperm transport in ovariectomized, oestrogen-treated rabbits Journal of Endocrinology. 61: 139-145. PMID 4829149  0.01
1974 Morton DB, Glover TD. Sperm transport in the female rabbit: The role of the cervix Journal of Reproduction and Fertility. 38: 131-138. PMID 4601825  0.01
1974 Morton DB, Bavister BD. Fractionation of hamster sperm-capacitating components from human serum by gel filtration. Journal of Reproduction and Fertility. 40: 491-3. PMID 4431004  0.01
1974 Morton DB, Fitzpatrick RJ, Glover TD. Sperm distribution in female rabbits: the effect of ovarian steroids. Acta Endocrinologica. 76: 765-72. PMID 4407895  0.01
1974 Bavister BD, Morton DB. Separation of human serum components capable of inducing the acrosome reaction in hamster spermatozoa. Journal of Reproduction and Fertility. 40: 495-8. PMID 4139258  0.01
1969 Morton DB, Rankin JE. The histology of the vaginal epithelium of the sow in oestrus and its use in pregnancy diagnosis Veterinary Record. 84: 658-662. PMID 5816775  0.01
1969 Morton DB. Influence of oxytocin on transport of spermatozoa in ovariectomized female rabbits Journal of Endocrinology. 45: Suppl:vi-vii. PMID 4899802  0.01
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