Howard Wheal - Publications

Affiliations: 
University of Southampton, Southampton, England, United Kingdom 

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Melyan Z, Wheal HV. Metabotropic actions of kainate receptors in the regulation of I(sAHP) and excitability in CA1 pyramidal cells. Advances in Experimental Medicine and Biology. 717: 49-58. PMID 21713666 DOI: 10.1007/978-1-4419-9557-5_5  0.367
2007 Grabauskas G, Lancaster B, O'Connor V, Wheal HV. Protein kinase signalling requirements for metabotropic action of kainate receptors in rat CA1 pyramidal neurones. The Journal of Physiology. 579: 363-73. PMID 17158174 DOI: 10.1113/Jphysiol.2006.122051  0.329
2006 Grabauskas G, Chapman H, Wheal HV. Role of protein kinase C in modulation of excitability of CA1 pyramidal neurons in the rat. Neuroscience. 139: 1301-13. PMID 16533575 DOI: 10.1016/j.neuroscience.2006.01.014  0.474
2004 Melyan Z, Lancaster B, Wheal HV. Metabotropic regulation of intrinsic excitability by synaptic activation of kainate receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4530-4. PMID 15140923 DOI: 10.1523/JNEUROSCI.5356-03.2004  0.461
2002 Melyan Z, Wheal HV, Lancaster B. Metabotropic-mediated kainate receptor regulation of IsAHP and excitability in pyramidal cells. Neuron. 34: 107-14. PMID 11931745 DOI: 10.1016/S0896-6273(02)00624-4  0.372
2001 Bernard C, Marsden DP, Wheal HV. Changes in neuronal excitability and synaptic function in a chronic model of temporal lobe epilepsy Neuroscience. 103: 17-26. PMID 11311784 DOI: 10.1016/S0306-4522(00)00524-8  0.708
1999 Chen Y, Chad JE, Cannon RC, Wheal HV. Reduced Mg2+ blockade of synaptically activated N-methyl-D-aspartate receptor-channels in CA1 pyramidal neurons in kainic acid-lesioned rat hippocampus. Neuroscience. 88: 727-39. PMID 10363813 DOI: 10.1016/S0306-4522(98)00253-X  0.737
1998 Bernard C, Pickering J, Wheal HV. Reversal of excitatory postsynaptic potential/spike potentiation in the CA1 area of the rat hippocampus Neuroscience. 86: 431-436. PMID 9881858 DOI: 10.1016/S0306-4522(98)00031-1  0.685
1998 Wheal HV, Chen Y, Mitchell J, Schachner M, Maerz W, Wieland H, Van Rossum D, Kirsch J. Molecular mechanisms that underlie structural and functional changes at the postsynaptic membrane during synaptic plasticity. Progress in Neurobiology. 55: 611-40. PMID 9670221 DOI: 10.1016/S0301-0082(98)00026-4  0.443
1998 Wheal HV, Chad JE, Cannon RC, Bernard C. Pro-epileptic changes in synaptic function can be accompanied by pro- epileptic changes in neuronal excitability Trends in Neurosciences. 21: 167-174. PMID 9554727 DOI: 10.1016/S0166-2236(97)01182-X  0.723
1997 Bernard C, Cannon RC, Ben Ari Y, Wheal HV. Model of spatio-temporal propagation of action potentials in the Schaffer collateral pathway of the CA1 area of the rat hippocampus. Hippocampus. 7: 58-72. PMID 9138669 DOI: 10.1002/(SICI)1098-1063(1997)7:1<58::AID-HIPO6>3.0.CO;2-3  0.545
1997 Chen Y, Chad JE, Wheal HV. Synaptic release rather than failure in the conditioning pulse results in paired-pulse facilitation during minimal synaptic stimulation in the rat hippocampal CA1 neurones. Neuroscience Letters. 218: 204-8. PMID 8945764 DOI: 10.1016/S0304-3940(96)13149-9  0.734
1996 Bernard C, Wheal HV. A role for synaptic and network plasticity in controlling epileptiform activity in CA1 in the kainic acid-lesioned rat hippocampus in vitro Journal of Physiology. 495: 127-142. PMID 8866357 DOI: 10.1113/Jphysiol.1996.Sp021579  0.669
1995 Bernard C, Wheal HV. Plasticity of AMPA and NMDA receptor-mediated epileptiform activity in a chronic model of temporal lobe epilepsy. Epilepsy Research. 21: 95-107. PMID 7588593 DOI: 10.1016/0920-1211(95)00017-5  0.629
1995 Bernard CL, Wheal HV. Simultaneous expression of long-term depression of NMDA and long-term potentiation of AMPA receptor-mediated synaptic responses in the CA1 area of the kainic acid-lesioned hippocampus European Journal of Neuroscience. 7: 1651-1655. PMID 7551191 DOI: 10.1111/j.1460-9568.1995.tb01160.x  0.459
1995 Stanford IM, Wheal HV, Chad JE. Bicuculline enhances the late GABAB receptor-mediated paired-pulse inhibition observed in rat hippocampal slices. European Journal of Pharmacology. 277: 229-34. PMID 7493613 DOI: 10.1016/0014-2999(95)00083-W  0.708
1995 Bernard C, Wheal HV. Simultaneous expression of excitatory postsynaptic potential/spike potentiation and excitatory postsynaptic potential/spike depression in the hippocampus Neuroscience. 67: 73-82. PMID 7477912 DOI: 10.1016/0306-4522(95)00008-7  0.679
1995 Bernard C, Wheal H. Expression of EPSP/spike potentiation following low frequency and tetanic stimulation in the CA1 area of the rat hippocampus The Journal of Neuroscience. 15: 6542-6551. DOI: 10.1523/Jneurosci.15-10-06542.1995  0.655
1994 Colling SB, Wheal HV. Fast sodium action potentials are generated in the distal apical dendrites of rat hippocampal CA1 pyramidal cells. Neuroscience Letters. 172: 73-96. PMID 8084540 DOI: 10.1016/0304-3940(94)90665-3  0.392
1994 Bernard C, Wheal HV. Model of local connectivity patterns in CA3 and CA1 areas of the hippocampus. Hippocampus. 4: 497-529. PMID 7889123 DOI: 10.1002/Hipo.450040502  0.563
1993 Isaac JT, Wheal HV. The local anaesthetic QX-314 enables enhanced whole-cell recordings of excitatory synaptic currents in rat hippocampal slices in vitro. Neuroscience Letters. 150: 227-30. PMID 8385755 DOI: 10.1016/0304-3940(93)90542-S  0.624
1993 Best N, Mitchell J, Baimbridge KG, Wheal HV. Changes in parvalbumin-immunoreactive neurons in the rat hippocampus following a kainic acid lesion. Neuroscience Letters. 155: 1-6. PMID 8361655 DOI: 10.1016/0304-3940(93)90660-D  0.308
1992 Edwards JG, Wheal HV. Assessment of epileptogenic potential: experimental, clinical and epidemiological approaches. Journal of Psychopharmacology (Oxford, England). 6: 204-13. PMID 22291352 DOI: 10.1177/026988119200600213  0.401
1992 Williamson R, Wheal HV. The contribution of AMPA and NMDA receptors to graded bursting activity in the hippocampal CA1 region in an acute in vitro model of epilepsy. Epilepsy Research. 12: 179-88. PMID 1356760 DOI: 10.1016/0920-1211(92)90039-V  0.475
1991 Phelps S, Mitchell J, Wheal HV. Changes to synaptic ultrastructure in field CA1 of the rat hippocampus following intracerebroventricular injection of kainic acid. Neuroscience. 40: 687-99. PMID 2062438 DOI: 10.1016/0306-4522(91)90005-9  0.319
1991 Wheal HV. Membrane electrophysiology of epileptiform activity in the hippocampus. Acta Neurochirurgica. Supplementum. 50: 6-13. PMID 1711270 DOI: 10.1007/978-3-7091-9104-0_2  0.316
1991 Simpson LH, Wheal HV, Williamson R. The contribution of non-NMDA and NMDA receptors to graded bursting activity in the CA1 region of the hippocampus in a chronic model of epilepsy. Canadian Journal of Physiology and Pharmacology. 69: 1091-8. PMID 1683263 DOI: 10.1139/Y91-161  0.387
1990 Spencer PM, Wheal HV. Synaptic inhibition in the rat hippocampus in vivo following stimulation of the substantia nigra and ventral tegmentum. The Journal of Physiology. 423: 77-90. PMID 1974925 DOI: 10.1113/jphysiol.1990.sp018012  0.419
1990 Wheal H. NMDA-receptors are involved in synaptic plasticity following partial denervation of CA1 hippocampal cells. Advances in Experimental Medicine and Biology. 268: 461-469. PMID 1963750 DOI: 10.1007/978-1-4684-5769-8_51  0.434
1989 Wheal HV. Function of synapses in the CA1 region of the hippocampus: their contribution to the generation or control of epileptiform activity. Comparative Biochemistry and Physiology. a, Comparative Physiology. 93: 211-20. PMID 2568224 DOI: 10.1016/0300-9629(89)90209-0  0.456
1987 Ashwood TJ, Collingridge GL, Herron CE, Wheal HV. Voltage-clamp analysis of somatic gamma-aminobutyric acid responses in adult rat hippocampal CA1 neurones in vitro. The Journal of Physiology. 384: 27-37. PMID 3656147  0.528
1987 Ashwood TJ, Wheal HV. The expression of N-methyl-D-aspartate-receptor-mediated component during epileptiform synaptic activity in hippocampus. British Journal of Pharmacology. 91: 815-22. PMID 2889490 DOI: 10.1111/j.1476-5381.1987.tb11280.x  0.482
1987 Andersen P, Storm J, Wheal HV. Thresholds of action potentials evoked by synapses on the dendrites of pyramidal cells in the rat hippocampus in vitro Journal of Physiology. 509-526. DOI: 10.1113/Jphysiol.1987.Sp016425  0.38
1986 Ashwood TJ, Wheal HV. Loss of inhibition in the CA1 region of the kainic acid lesioned hippocampus is not associated with changes in postsynaptic responses to GABA. Brain Research. 367: 390-4. PMID 3008925 DOI: 10.1016/0006-8993(86)91625-2  0.303
1986 Ashwood TJ, Lancaster B, Wheal HV. Intracellular electrophysiology of CA1 pyramidal neurones in slices of the kainic acid lesioned hippocampus of the rat. Experimental Brain Research. 62: 189-98. PMID 3007192 DOI: 10.1007/BF00237415  0.402
1986 Ashwood TJ, Wheal HV. Extracellular studies on the role of N-methyl-D-aspartate receptors in epileptiform activity recorded from the kainic acid-lesioned hippocampus. Neuroscience Letters. 67: 147-52. PMID 2873533 DOI: 10.1016/0304-3940(86)90388-5  0.392
1984 Lancaster B, Wheal HV. The synaptically evoked late hyperpolarisation in hippocampal CA1 pyramidal cells is resistant to intracellular EGTA. Neuroscience. 12: 267-75. PMID 6431312 DOI: 10.1016/0306-4522(84)90152-0  0.448
1984 Ashwood TJ, Lancaster B, Wheal HV. In vivo and in vitro studies on putative interneurones in the rat hippocampus: possible mediators of feed-forward inhibition. Brain Research. 293: 279-91. PMID 6320970 DOI: 10.1016/0006-8993(84)91235-6  0.393
1984 McBain AE, Wheal HV. The piperidine analogues prevent desensitization of glutamate receptors on crustacean muscle. Brain Research. 290: 307-10. PMID 6318911 DOI: 10.1016/0006-8993(84)90948-X  0.317
1984 McBain AE, Wheal HV. Further structure activity studies on the excitatory amino acid receptors of the crustacean neuromuscular junction. Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology. 77: 357-62. PMID 6144443 DOI: 10.1016/0742-8413(84)90028-8  0.321
1984 McBain AE, Wheal HV, Collins JF. The pharmacology of the piperidine dicarboxylates on the crustacean neuromuscular junction. Neuropharmacology. 23: 23-30. PMID 6144064 DOI: 10.1016/0028-3908(84)90212-0  0.361
1984 Knowles WD, Schneiderman JH, Wheal HV, Stafstrom CE, Schwartzkroin PA. Hyperpolarizing potentials in guinea pig hippocampal CA3 neurons. Cellular and Molecular Neurobiology. 4: 207-30. PMID 6098369 DOI: 10.1007/Bf00733586  0.392
1984 Wheal HV, Thomson AM. The electrical properties of neurones of the rat suprachiasmatic nucleus recorded intracellularly in vitro. Neuroscience. 13: 97-104. PMID 6092997 DOI: 10.1016/0306-4522(84)90262-8  0.448
1983 King DJ, Wheal HV, Sharma RP, Kerkut GA. Kainic acid derivatives as excitants of lateral geniculate relay neurons. Brain Research. 262: 172-6. PMID 6831229 DOI: 10.1016/0006-8993(83)90484-5  0.51
1983 Wheal HV, Lancaster B, Bliss TV. Long-term potentiation in Schaffer collateral and commissural systems of the hippocampus: in vitro study in rats pretreated with kainic acid. Brain Research. 272: 247-53. PMID 6311340 DOI: 10.1016/0006-8993(83)90570-X  0.374
1980 Wheal HV, Miller JJ. Pharmacological identification of acetylcholine and glutamate excitatory systems in the dentate gyrus of the rat. Brain Research. 182: 145-55. PMID 6243231 DOI: 10.1016/0006-8993(80)90837-9  0.394
1976 Wheal HV, Kerkut GA. The action of muscimol on the inhibitory postsynaptic membrane of the crustacean neuromuscular junction. Brain Research. 109: 179-83. PMID 945113 DOI: 10.1016/0006-8993(76)90390-5  0.527
1976 Wheal HV, Kerkut GA. The pre- and post-synaptic actions of 5HT in Crustacea. Comparative Biochemistry and Physiology. C: Comparative Pharmacology. 54: 67-70. PMID 8258 DOI: 10.1016/0306-4492(76)90065-4  0.515
1976 Wheal HV, Kerkut GA. Structure activity studies on the excitatory receptor of the crustacean neuromuscular junction. Comparative Biochemistry and Physiology. C: Comparative Pharmacology. 53: 51-5. PMID 3384 DOI: 10.1016/0306-4492(76)90050-2  0.544
1976 Wheal HV, Kerkut GA. Electrophysiological and morphological investigations on the neuromuscular junction of the hermit crab, Eupagurus bernhardus. Comparative Biochemistry and Physiology. a, Comparative Physiology. 54: 13-8. PMID 3335 DOI: 10.1016/S0300-9629(76)80063-1  0.454
1974 Wheal HV, Kerkut GA. The effect of diethyl ester L-glutamate on evoked excitatory junction potentials at the crustacean neuromuscular junction. Brain Research. 82: 338-40. PMID 4374296 DOI: 10.1016/0006-8993(74)90616-7  0.55
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