Richard C. Mulligan - Publications

Affiliations: 
2007 Rosalind Franklin University of Medicine and Science, North Chicago, IL, United States 

132 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Burkhardt UE, Hainz U, Stevenson K, Goldstein NR, Pasek M, Naito M, Wu D, Ho VT, Alonso A, Hammond NN, Wong J, Sievers QL, Brusic A, McDonough SM, Zeng W, ... ... Mulligan RC, et al. Autologous CLL cell vaccination early after transplant induces leukemia-specific T cells. The Journal of Clinical Investigation. 123: 3756-65. PMID 23912587 DOI: 10.1172/Jci69098  0.334
2012 Brusic A, Hainz U, Wadleigh M, Neuberg D, Su M, Canning CM, Deangelo DJ, Stone RM, Lee JS, Mulligan RC, Ritz J, Dranoff G, Sasada T, Wu CJ. Detecting T-cell reactivity to whole cell vaccines: Proof of concept analysis of T-cell response to K562 cell antigens in CML patients. Oncoimmunology. 1: 1095-1103. PMID 23170257 DOI: 10.4161/Onci.20954  0.35
2012 Herson S, Hentati F, Rigolet A, Behin A, Romero NB, Leturcq F, Laforêt P, Maisonobe T, Amouri R, Haddad H, Audit M, Montus M, Masurier C, Gjata B, Georger C, ... ... Mulligan RC, et al. A phase I trial of adeno-associated virus serotype 1-γ-sarcoglycan gene therapy for limb girdle muscular dystrophy type 2C. Brain : a Journal of Neurology. 135: 483-92. PMID 22240777 DOI: 10.1093/Brain/Awr342  0.304
2011 Mulligan RC, Knopik VS, Sweet LH, Fischer M, Seidenberg M, Rao SM. Neural correlates of inhibitory control in adult attention deficit/hyperactivity disorder: evidence from the Milwaukee longitudinal sample. Psychiatry Research. 194: 119-29. PMID 21937201 DOI: 10.1016/J.Pscychresns.2011.02.003  0.485
2011 Schwenter F, Zarei S, Luy P, Padrun V, Bouche N, Lee JS, Mulligan RC, Morel P, Mach N. Cell encapsulation technology as a novel strategy for human anti-tumor immunotherapy. Cancer Gene Therapy. 18: 553-62. PMID 21566667 DOI: 10.1038/Cgt.2011.22  0.353
2011 Sahin E, Colla S, Liesa M, Moslehi J, Müller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C, Maser RS, Tonon G, Foerster F, Xiong R, Wang YA, ... ... Mulligan R, et al. Telomere dysfunction induces metabolic and mitochondrial compromise. Nature. 470: 359-65. PMID 21307849 DOI: 10.1038/Nature09787  0.542
2011 Sanchez CE, Tierney TS, Gale JT, Alavian KN, Sahin A, Lee JS, Mulligan RC, Carter BS. Recombinant adeno-associated virus type 2 pseudotypes: comparing safety, specificity, and transduction efficiency in the primate striatum. Laboratory investigation. Journal of Neurosurgery. 114: 672-80. PMID 20950087 DOI: 10.3171/2010.8.Jns091583  0.309
2011 Sahin E, Colla S, Liesa M, Moslehi J, Müller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C, Maser RS, Tonon G, Foerster F, Xiong R, Wang YA, ... ... Mulligan R, et al. Erratum: Telomere dysfunction induces metabolic and mitochondrial compromise Nature. 475: 254-254. DOI: 10.1038/Nature10223  0.498
2010 Wilson AA, Murphy GJ, Hamakawa H, Kwok LW, Srinivasan S, Hovav AH, Mulligan RC, Amar S, Suki B, Kotton DN. Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages. The Journal of Clinical Investigation. 120: 379-89. PMID 20038801 DOI: 10.1172/Jci36666  0.621
2009 Bullain SS, Sahin A, Szentirmai O, Sanchez C, Lin N, Baratta E, Waterman P, Weissleder R, Mulligan RC, Carter BS. Genetically engineered T cells to target EGFRvIII expressing glioblastoma. Journal of Neuro-Oncology. 94: 373-82. PMID 19387557 DOI: 10.1007/S11060-009-9889-1  0.352
2008 Rodino-Klapac LR, Lee JS, Mulligan RC, Clark KR, Mendell JR. Lack of toxicity of alpha-sarcoglycan overexpression supports clinical gene transfer trial in LGMD2D. Neurology. 71: 240-7. PMID 18525034 DOI: 10.1212/01.Wnl.0000306309.85301.E2  0.318
2008 Szentirmai O, Baker CH, Bullain SS, Lin N, Takahashi M, Folkman J, Mulligan RC, Carter BS. Successful inhibition of intracranial human glioblastoma multiforme xenograft growth via systemic adenoviral delivery of soluble endostatin and soluble vascular endothelial growth factor receptor-2: laboratory investigation. Journal of Neurosurgery. 108: 979-88. PMID 18447716 DOI: 10.3171/Jns/2008/108/5/0979  0.306
2007 Chan RK, Garfein E, Gigante PR, Liu P, Agha RA, Mulligan R, Orgill DP. Side population hematopoietic stem cells promote wound healing in diabetic mice. Plastic and Reconstructive Surgery. 120: 407-11; discussion 4. PMID 17632341 DOI: 10.1097/01.Prs.0000267696.98789.66  0.301
2007 Butler MO, Lee JS, Ansén S, Neuberg D, Hodi FS, Murray AP, Drury L, Berezovskaya A, Mulligan RC, Nadler LM, Hirano N. Long-lived antitumor CD8+ lymphocytes for adoptive therapy generated using an artificial antigen-presenting cell. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 1857-67. PMID 17363542 DOI: 10.1158/1078-0432.Ccr-06-1905  0.327
2006 Mostoslavsky G, Fabian AJ, Rooney S, Alt FW, Mulligan RC. Complete correction of murine Artemis immunodeficiency by lentiviral vector-mediated gene transfer. Proceedings of the National Academy of Sciences of the United States of America. 103: 16406-11. PMID 17062750 DOI: 10.1073/Pnas.0608130103  0.418
2006 Murphy GJ, Mostoslavsky G, Kotton DN, Mulligan RC. Exogenous control of mammalian gene expression via modulation of translational termination. Nature Medicine. 12: 1093-9. PMID 16892063 DOI: 10.1038/Nm1376  0.598
2006 Balazs AB, Fabian AJ, Esmon CT, Mulligan RC. Endothelial protein C receptor (CD201) explicitly identifies hematopoietic stem cells in murine bone marrow. Blood. 107: 2317-21. PMID 16304059 DOI: 10.1182/Blood-2005-06-2249  0.381
2005 Kotton DN, Fabian AJ, Mulligan RC. Failure of bone marrow to reconstitute lung epithelium. American Journal of Respiratory Cell and Molecular Biology. 33: 328-34. PMID 15961722 DOI: 10.1165/Rcmb.2005-0175Rc  0.591
2005 Mostoslavsky G, Kotton DN, Fabian AJ, Gray JT, Lee JS, Mulligan RC. Efficiency of transduction of highly purified murine hematopoietic stem cells by lentiviral and oncoretroviral vectors under conditions of minimal in vitro manipulation. Molecular Therapy : the Journal of the American Society of Gene Therapy. 11: 932-40. PMID 15922964 DOI: 10.1016/J.Ymthe.2005.01.005  0.613
2005 Kotton DN, Fabian AJ, Mulligan RC. A novel stem-cell population in adult liver with potent hematopoietic-reconstitution activity. Blood. 106: 1574-80. PMID 15870171 DOI: 10.1182/Blood-2005-03-1017  0.593
2004 Tani K, Azuma M, Nakazaki Y, Oyaizu N, Hase H, Ohata J, Takahashi K, OiwaMonna M, Hanazawa K, Wakumoto Y, Kawai K, Noguchi M, Soda Y, Kunisaki R, Watari K, ... ... Mulligan R, et al. Phase I study of autologous tumor vaccines transduced with the GM-CSF gene in four patients with stage IV renal cell cancer in Japan: clinical and immunological findings. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 799-816. PMID 15451464 DOI: 10.1016/J.Ymthe.2004.07.001  0.321
2004 Yen L, Svendsen J, Lee JS, Gray JT, Magnier M, Baba T, D'Amato RJ, Mulligan RC. Exogenous control of mammalian gene expression through modulation of RNA self-cleavage. Nature. 431: 471-6. PMID 15386015 DOI: 10.1038/Nature02844  0.318
2004 Michurina T, Krasnov P, Balazs A, Nakaya N, Vasilieva T, Kuzin B, Khrushchov N, Mulligan RC, Enikolopov G. Nitric oxide is a regulator of hematopoietic stem cell activity. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 241-8. PMID 15294171 DOI: 10.1016/J.Ymthe.2004.05.030  0.337
2004 Matsuzaki Y, Kinjo K, Mulligan RC, Okano H. Unexpectedly efficient homing capacity of purified murine hematopoietic stem cells. Immunity. 20: 87-93. PMID 14738767 DOI: 10.1016/S1074-7613(03)00354-6  0.351
2004 Banu N, Fabian A, Mulligan RC. Functional Studies of Human Bone Marrow Derived Side Population Cells. Blood. 104: 3221-3221. DOI: 10.1182/Blood.V104.11.3221.3221  0.365
2004 Butler MO, Hirano N, Lee J, Beecham EJ, Chung M, Ripley R, Murray AP, Mulligan RC, Nadler LM. Off the Shelf, GMP Grade Artificial APC Efficiently Generates Large Numbers of Antigen Specific CTLs Sufficient for the Treatment of Cancer and Infectious Disease. Blood. 104: 3172-3172. DOI: 10.1182/Blood.V104.11.3172.3172  0.327
2003 Griese DP, Ehsan A, Melo LG, Kong D, Zhang L, Mann MJ, Pratt RE, Mulligan RC, Dzau VJ. Isolation and transplantation of autologous circulating endothelial cells into denuded vessels and prosthetic grafts: implications for cell-based vascular therapy. Circulation. 108: 2710-5. PMID 14597586 DOI: 10.1161/01.Cir.0000096490.16596.A6  0.361
2003 Soiffer R, Hodi FS, Haluska F, Jung K, Gillessen S, Singer S, Tanabe K, Duda R, Mentzer S, Jaklitsch M, Bueno R, Clift S, Hardy S, Neuberg D, Mulligan R, et al. Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 3343-50. PMID 12947071 DOI: 10.1200/Jco.2003.07.005  0.334
2003 Kettner A, Pivniouk V, Kumar L, Falet H, Lee JS, Mulligan R, Geha RS. Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells. Molecular and Cellular Biology. 23: 2395-406. PMID 12640123 DOI: 10.1128/Mcb.23.7.2395-2406.2003  0.313
2003 Salgia R, Lynch T, Skarin A, Lucca J, Lynch C, Jung K, Hodi FS, Jaklitsch M, Mentzer S, Swanson S, Lukanich J, Bueno R, Wain J, Mathisen D, Wright C, ... ... Mulligan R, et al. Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 21: 624-30. PMID 12586798 DOI: 10.1200/Jco.2003.03.091  0.318
2003 Klein C, Nguyen D, Liu CH, Mizoguchi A, Bhan AK, Miki H, Takenawa T, Rosen FS, Alt FW, Mulligan RC, Snapper SB. Gene therapy for Wiskott-Aldrich syndrome: rescue of T-cell signaling and amelioration of colitis upon transplantation of retrovirally transduced hematopoietic stem cells in mice. Blood. 101: 2159-66. PMID 12433691 DOI: 10.1182/Blood-2002-05-1423  0.399
2002 Tseng JF, Mulligan RC. Gene therapy for pancreatic cancer. Surgical Oncology Clinics of North America. 11: 537-69. PMID 12487056 DOI: 10.1016/S1055-3207(02)00023-6  0.348
2002 Tseng JF, Farnebo FA, Kisker O, Becker CM, Kuo CJ, Folkman J, Mulligan RC. Adenovirus-mediated delivery of a soluble form of the VEGF receptor Flk1 delays the growth of murine and human pancreatic adenocarcinoma in mice. Surgery. 132: 857-65. PMID 12464871 DOI: 10.1067/Msy.2002.127680  0.326
2002 Ramalho-Santos M, Yoon S, Matsuzaki Y, Mulligan RC, Melton DA. "Stemness": transcriptional profiling of embryonic and adult stem cells. Science (New York, N.Y.). 298: 597-600. PMID 12228720 DOI: 10.1126/Science.1072530  0.356
2002 Kawai K, Tani K, Yamashita N, Tomikawa S, Eriguchi M, Fujime M, Okumura K, Kakizoe T, Clift S, Ando D, Mulligan R, Yamauchi A, Noguchi M, Asano S, Akaza H. Advanced renal cell carcinoma treated with granulocyte-macrophage colony-stimulating factor gene therapy: a clinical course of the first Japanese experience. International Journal of Urology : Official Journal of the Japanese Urological Association. 9: 462-6. PMID 12225344 DOI: 10.1046/J.1442-2042.2002.00493.X  0.345
2002 Heinz M, Huang CA, Emery DW, Giovino MA, LeGuern A, Kurilla-Mahon B, Theodore P, Arn JS, Sykes M, Mulligan R, Down JD, Sachs DH, Goodell MA. Use of CD9 expression to enrich for porcine hematopoietic progenitors. Experimental Hematology. 30: 809-15. PMID 12135680 DOI: 10.1016/S0301-472X(02)00835-4  0.35
2002 Niederman TM, Ghogawala Z, Carter BS, Tompkins HS, Russell MM, Mulligan RC. Antitumor activity of cytotoxic T lymphocytes engineered to target vascular endothelial growth factor receptors. Proceedings of the National Academy of Sciences of the United States of America. 99: 7009-14. PMID 11997459 DOI: 10.1073/Pnas.092562399  0.345
2001 Kuo CJ, Farnebo F, Yu EY, Christofferson R, Swearingen RA, Carter R, Von Recum HA, Yuan J, Kamihara J, Flynn E, D'Amato R, Folkman J, Mulligan RC. Comparative evaluation of the antitumor activity of antiangiogenic proteins delivered by gene transfer Proceedings of the National Academy of Sciences of the United States of America. 98: 4605-4610. PMID 11274374 DOI: 10.1073/Pnas.081615298  0.329
2001 Tseng JF, Farnebo FA, Kisker O, Becker CM, Kuo CJ, Folkman J, Mulligan RC. Antiangiogenic gene therapy delays growth of murine and human pancreatic adenocarcinoma in mice Gastroenterology. 120: A349. DOI: 10.1016/S0016-5085(08)81737-4  0.313
2000 Snitkovsky S, Niederman TM, Carter BS, Mulligan RC, Young JA. A TVA-single-chain antibody fusion protein mediates specific targeting of a subgroup A avian leukosis virus vector to cells expressing a tumor-specific form of epidermal growth factor receptor. Journal of Virology. 74: 9540-5. PMID 11000224 DOI: 10.1128/Jvi.74.20.9540-9545.2000  0.317
2000 Tani K, Nakazaki Y, Hase H, Takahashi K, Azuma M, Ohata J, Kitamura R, Komine F, Oiwa M, Masunaga A, Maekawa T, Satoh N, Adachi D, Soda Y, Machida U, ... ... Mulligan R, et al. Progress reports on immune gene therapy for stage IV renal cell cancer using lethally irradiated granulocyte-macrophage colony-stimulating factor-transduced autologous renal cancer cells Cancer Chemotherapy and Pharmacology. 46: S73-S76. PMID 10950152 DOI: 10.1007/Pl00014054  0.322
2000 Nelson WG, Simons JW, Mikhak B, Chang JF, DeMarzo AM, Carducci MA, Kim M, Weber CE, Baccala AA, Goeman MA, Clift SM, Ando DG, Levitsky HI, Cohen LK, Sanda MG, ... Mulligan RC, et al. Cancer cells engineered to secrete granulocyte-macrophage colony-stimulating factor using ex vivo gene transfer as vaccines for the treatment of genitourinary malignancies. Cancer Chemotherapy and Pharmacology. 46: S67-72. PMID 10950151 DOI: 10.1007/Pl00014053  0.301
2000 Dahl AM, Klein C, Andres PG, London CA, Lodge MP, Mulligan RC, Abbas AK. Expression of Bcl-X(L) restores cell survival, but not proliferation and effector differentiation, in CD28-deficient T lymphocytes Journal of Experimental Medicine. 191: 2031-2037. PMID 10859328 DOI: 10.1084/Jem.191.12.2031  0.326
2000 Klein C, Bueler H, Mulligan RC. Comparative analysis of genetically modified dendritic cells and tumor cells as therapeutic cancer vaccines Journal of Experimental Medicine. 191: 1699-1708. PMID 10811863 DOI: 10.1084/Jem.191.10.1699  0.342
2000 Storms RW, Goodell MA, Fisher A, Mulligan RC, Smith C. Hoechst dye efflux reveals a novel CD7+CD34− lymphoid progenitor in human umbilical cord blood Blood. 96: 2125-2133. DOI: 10.1182/Blood.V96.6.2125.H8002125_2125_2133  0.34
2000 Salgia R, Lynch T, Skarin A, Lynch C, Lucca J, Jaklitsch M, Mentzer S, Swanson S, Lukanich J, Bueno R, DeCamp M, Wain J, Mathiesen D, Wright C, Carey R, ... ... Mulligan R, et al. A phase I study of vaccination with lethally irradiated, autologous nonsmall cell lung carcinoma cells engineered by adenoviral mediated gene transfer to secrete human granulocyte-macrophage colony stimulating factor Lung Cancer. 29: 186. DOI: 10.1016/S0169-5002(00)80626-1  0.34
1999 Gussoni E, Soneoka Y, Strickland CD, Buzney EA, Khan MK, Flint AF, Kunkel LM, Mulligan RC. Dystrophin expression in the mdx mouse restored by stem cell transplantation. Nature. 401: 390-4. PMID 10517639 DOI: 10.1038/43919  0.372
1999 Zehntner S, Townsend W, Parkes J, Schmidt C, Down M, Bell J, Mulligan R, O'Rourke M, Ellem K, Thomas R. Tumor metastasis biopsy as a surrogate marker of response to melanoma immunotherapy Pathology. 31: 116-122. PMID 10399166 DOI: 10.1080/003130299105296  0.301
1999 Rebel VI, Tanaka M, Lee JS, Hartnett S, Pulsipher M, Nathan DG, Mulligan RC, Sieff CA. One-day ex vivo culture allows effective gene transfer into human nonobese diabetic/severe combined immune-deficient repopulating cells using high-titer vesicular stomatitis virus G protein pseudotyped retrovirus. Blood. 93: 2217-2224. DOI: 10.1182/Blood.V93.7.2217  0.382
1998 Pulsipher M, Kupfer GM, Naf D, Suliman A, Lee JS, Jakobs P, Grompe M, Joenje H, Sieff C, Guinan E, Mulligan R, D'Andrea AD. Subtyping analysis of Fanconi anemia by immunoblotting and retroviral gene transfer Molecular Medicine. 4: 468-479. PMID 9713825 DOI: 10.1007/Bf03401752  0.345
1998 Sonderbye L, Feng S, Yacoubian S, Buehler H, Ahsan N, Mulligan R, Langhoff E. In vivo and in vitro modulation of immune stimulatory capacity of primary dendritic cells by adenovirus-mediated gene transduction Experimental and Clinical Immunogenetics. 15: 100-111. PMID 9691204 DOI: 10.1159/000019060  0.337
1998 McArthur JG, Mulligan RC. Induction of protective anti-tumor immunity by gene-modified dendritic cells Journal of Immunotherapy. 21: 41-47. PMID 9456435 DOI: 10.1097/00002371-199801000-00005  0.32
1998 Ahsan N, Sonderbye L, Feng S, Bennekov T, Mulligan R, Langhoff E. MODULATION OF IMMUNE RESPONSES INDUCED BY GENE TRANSDUCED DENDRITIC CELLS Transplantation. 65: 107. DOI: 10.1097/00007890-199805131-00115  0.324
1998 Carter BS, Zoher G, Niederman T, Mulligan R. Specific Killing of EGFRvIII Expressing Tumor Cells by Genetically Engineered Cytotoxic T Lymphocytes Neurosurgery. 43: 709-710. DOI: 10.1097/00006123-199809000-00335  0.311
1998 Simons J, Jaffee E, Weber C, Levitsky H, Nelson W, Carducci M, Lazenby A, Cohen L, Finn C, Clift S, Hauda K, Beck L, Leiferman K, Owens A, Piantadosi S, ... ... Mulligan R, et al. Bioactivity of Autologous Irradiated Renal Cell Carcinoma Vaccines Generated by Ex Vivo Granulocyte-Macrophage Colony-Stimulating Factor Gene Transfer Journal of Urology. 159: 617-618. DOI: 10.1016/S0022-5347(01)63906-5  0.313
1997 Goodell MA, Rosenzweig M, Kim H, Marks DF, DeMaria M, Paradis G, Grupp SA, Sieff CA, Mulligan RC, Johnson RP. Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species. Nature Medicine. 3: 1337-45. PMID 9396603 DOI: 10.1038/Nm1297-1337  0.37
1997 Kaptein LC, Van Beusechem VW, Rivière I, Mulligan RC, Valerio D. Long-term in vivo expression of the MFG-ADA retroviral vector in rhesus monkeys transplanted with transduced bone marrow cells. Human Gene Therapy. 8: 1605-10. PMID 9322093 DOI: 10.1089/Hum.1997.8.13-1605  0.376
1997 Ellem KA, O'Rourke MG, Johnson GR, Parry G, Misko IS, Schmidt CW, Parsons PG, Burrows SR, Cross S, Fell A, Li CL, Bell JR, Dubois PJ, Moss DJ, Good MF, ... ... Mulligan RC, et al. A case report: immune responses and clinical course of the first human use of granulocyte/macrophage-colony-stimulating-factor-transduced autologous melanoma cells for immunotherapy. Cancer Immunology, Immunotherapy : Cii. 44: 10-20. PMID 9111579 DOI: 10.1007/S002620050349  0.314
1997 Chang AE, Sondak VK, Bishop DK, Nickoloff BJ, Mulligan RC, Mulé JJ. Adoptive immunotherapy of cancer with activated lymph node cells primed in vivo with autologous tumor cells transduced with the GM-CSF gene. Human Gene Therapy. 7: 773-92. PMID 9053030 DOI: 10.1089/Hum.1996.7.6-773  0.357
1997 Lindemann D, Patriquin E, Feng S, Mulligan RC. Versatile retrovirus vector systems for regulated gene expression in vitro and in vivo. Molecular Medicine. 3: 466-476. DOI: 10.1007/Bf03401693  0.334
1996 Ory DS, Neugeboren BA, Mulligan RC. A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes Proceedings of the National Academy of Sciences of the United States of America. 93: 11400-11406. PMID 8876147 DOI: 10.1073/Pnas.93.21.11400  0.374
1996 Goodell MA, Brose K, Paradis G, Conner AS, Mulligan RC. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. The Journal of Experimental Medicine. 183: 1797-806. PMID 8666936 DOI: 10.1084/Jem.183.4.1797  0.376
1996 Dewerchin M, Nuffelen AV, Wallays G, Bouché A, Moons L, Carmeliet P, Mulligan RC, Collen D. Generation and characterization of urokinase receptor-deficient mice. The Journal of Clinical Investigation. 97: 870-8. PMID 8609247 DOI: 10.1172/Jci118489  0.303
1996 Huffman JA, Hull WM, Dranoff G, Mulligan RC, Whitsett JA. Pulmonary epithelial cell expression of GM-CSF corrects the alveolar proteinosis in GM-CSF-deficient mice. The Journal of Clinical Investigation. 97: 649-55. PMID 8609219 DOI: 10.1172/Jci118461  0.304
1996 Naldini L, Blömer U, Gallay P, Ory D, Mulligan R, Gage FH, Verma IM, Trono D. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science (New York, N.Y.). 272: 263-7. PMID 8602510 DOI: 10.1126/Science.272.5259.263  0.368
1996 Büeler H, Mulligan RC. Induction of Antigen-Specific Tumor Immunity by Genetic and Cellular Vaccines against MAGE: Enhanced Tumor Protection by Coexpression of Granulocyte-Macrophage Colony-Stimulating Factor and B7-1 Molecular Medicine. 2: 545-555. DOI: 10.1007/Bf03401639  0.309
1995 Hurford RK, Dranoff G, Mulligan RC, Tepper RI. Gene therapy of metastatic cancer by in vivo retroviral gene targeting. Nature Genetics. 10: 430-5. PMID 7670493 DOI: 10.1038/Ng0895-430  0.374
1995 Rivière I, Brose K, Mulligan RC. Effects of retroviral vector design on expression of human adenosine deaminase in murine bone marrow transplant recipients engrafted with genetically modified cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 6733-7. PMID 7624312 DOI: 10.1073/Pnas.92.15.6733  0.401
1995 Sadelain M, Wang CH, Antoniou M, Grosveld F, Mulligan RC. Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene. Proceedings of the National Academy of Sciences of the United States of America. 92: 6728-32. PMID 7624311 DOI: 10.1073/Pnas.92.15.6728  0.349
1995 Gerritsen WR, Spits H, Berk Pv, Batchelor D, Nooijen W, Berns A, Gallee M, Rockovich J, Clift S, Mulligan R, Rankin E. 998 Immunotherapy with autologous, irradiated melanoma cells transduced with the GM-CSF gene European Journal of Cancer. 31. DOI: 10.1016/0959-8049(95)96246-A  0.354
1995 McKinney CE, Sidransky E, Lamarca ME, Riviere I, Holleran WM, Martin BM, Willemsen R, Mulligan RC, Ginns EI. Gaucher disease: A tale of two species Mental Retardation and Developmental Disabilities Research Reviews. 1: 79-86. DOI: 10.1002/Mrdd.1410010114  0.37
1994 Karaplis AC, Luz A, Glowacki J, Bronson RT, Tybulewicz VL, Kronenberg HM, Mulligan RC. Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene. Genes & Development. 8: 277-89. PMID 8314082 DOI: 10.1101/Gad.8.3.277  0.327
1994 Conte MS, Birinyi LK, Miyata T, Fallon JT, Gold HK, Whittemore AD, Mulligan RC. Efficient repopulation of denuded rabbit arteries with autologous genetically modified endothelial cells. Circulation. 89: 2161-9. PMID 8181141 DOI: 10.1161/01.Cir.89.5.2161  0.316
1994 Vogt PM, Thompson S, Andree C, Liu P, Breuing K, Hatzis D, Brown H, Mulligan RC, Eriksson E. Genetically modified keratinocytes transplanted to wounds reconstitute the epidermis. Proceedings of the National Academy of Sciences of the United States of America. 91: 9307-11. PMID 7937761 DOI: 10.1073/Pnas.91.20.9307  0.321
1994 XP, Leonardsson G, Carmeliet P, Mulligan R, Collen D, Ny T. Regulation of the fibrinolytic system during gonadotropin-induced ovulation in mice with inactivation of the genes encoding tPA, uPA or PAI-i Fibrinolysis and Proteolysis. 8: 101. DOI: 10.1016/0268-9499(94)90566-5  0.319
1994 Dewerchin M, Carmeliet P, Van Nuffelen A, Collen D, Mulligan R. Inactivation of the mouse urokinase-receptor gene Fibrinolysis. 8: 51. DOI: 10.1016/0268-9499(94)90427-8  0.301
1993 Mulligan RC. The basic science of gene therapy. Science (New York, N.Y.). 260: 926-32. PMID 8493530 DOI: 10.1126/Science.8493530  0.345
1993 Sekhsaria S, Gallin JI, Linton GF, Mallory RM, Mulligan RC, Malech HL. Peripheral blood progenitors as a target for genetic correction of p47phox-deficient chronic granulomatous disease. Proceedings of the National Academy of Sciences of the United States of America. 90: 7446-50. PMID 8395049 DOI: 10.1073/Pnas.90.16.7446  0.338
1993 Silver DP, Spanopoulou E, Mulligan RC, Baltimore D. Dispensable sequence motifs in the RAG-1 and RAG-2 genes for plasmid V(D)J recombination. Proceedings of the National Academy of Sciences of the United States of America. 90: 6100-4. PMID 8327489 DOI: 10.1073/Pnas.90.13.6100  0.321
1993 Dranoff G, Jaffee E, Lazenby A, Golumbek P, Levitsky H, Brose K, Jackson V, Hamada H, Pardoll D, Mulligan RC. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proceedings of the National Academy of Sciences of the United States of America. 90: 3539-43. PMID 8097319 DOI: 10.1073/Pnas.90.8.3539  0.336
1992 Spain LM, Mulligan RC. Purification and characterization of retrovirally transduced hematopoietic stem cells Proceedings of the National Academy of Sciences of the United States of America. 89: 3790-3794. PMID 1570297 DOI: 10.1073/Pnas.89.9.3790  0.398
1992 Wilson JM, Grossman M, Thompson AR, Lupassikis C, Rosenberg A, Potts JT, Kronenberg HM, Mulligan RC, Nussbaum SR. Somatic gene transfer in the development of an animal model for primary hyperparathyroidism. Endocrinology. 130: 2947-54. PMID 1315263 DOI: 10.1210/Endo.130.5.1315263  0.36
1991 Tybulewicz VLJ, Crawford CE, Jackson PK, Bronson RT, Mulligan RC. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene Cell. 65: 1153-1163. PMID 2065352 DOI: 10.1016/0092-8674(91)90011-M  0.349
1991 Robbins PD, Horowitz JM, Mulligan RC. Correction: Negative regulation of human c-fos expression by the retinoblastoma gene product Nature. 351: 419-419. DOI: 10.1038/351419A0  0.303
1990 Wilson JM, Danos O, Grossman M, Raulet DH, Mulligan RC. Expression of human adenosine deaminase in mice reconstituted with retrovirus-transduced hematopoietic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 439-43. PMID 2296599 DOI: 10.1073/Pnas.87.1.439  0.382
1990 Wilson JM, Chowdhury NR, Grossman M, Wajsman R, Epstein A, Mulligan RC, Chowdhury JR. Temporary amelioration of hyperlipidemia in low density lipoprotein receptor-deficient rabbits transplanted with genetically modified hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 87: 8437-41. PMID 2236051 DOI: 10.1073/Pnas.87.21.8437  0.322
1990 Robbins PD, Horowitz JM, Mulligan RC. Negative regulation of human c-fos expression by thes retinoblastoma gene product Nature. 346: 668-671. PMID 2117257 DOI: 10.1038/346668A0  0.36
1989 Dzierzak EA, Mulligan RC. Lineage specific expression of a human beta-globin gene in murine bone marrow transplant recipients. Advances in Experimental Medicine and Biology. 241: 41-3. PMID 3066166 DOI: 10.1007/978-1-4684-5571-7_7  0.383
1989 Stuhlmann H, Jaenisch R, Mulligan RC. Construction and properties of replication-competent murine retroviral vectors encoding methotrexate resistance. Molecular and Cellular Biology. 9: 100-8. PMID 2927389 DOI: 10.1128/Mcb.9.1.100  0.316
1989 Stuhlmann H, Jaenisch R, Mulligan RC. Transfer of a mutant dihydrofolate reductase gene into pre- and postimplantation mouse embryos by a replication-competent retrovirus vector. Journal of Virology. 63: 4857-65. PMID 2795720 DOI: 10.1128/Jvi.63.11.4857-4865.1989  0.327
1989 Wilson JM, Birinyi LK, Salomon RN, Libby P, Callow AD, Mulligan RC. Implantation of vascular grafts lined with genetically modified endothelial cells. Science (New York, N.Y.). 244: 1344-6. PMID 2734614 DOI: 10.1126/Science.2734614  0.309
1989 Lenardo MJ, Staudt L, Robbins P, Kuang A, Mulligan RC, Baltimore D. Repression of the IgH enhancer in teratocarcinoma cells associated with a novel octamer factor. Science (New York, N.Y.). 243: 544-6. PMID 2536195 DOI: 10.1126/Science.2536195  0.329
1989 Barrandon Y, Morgan JR, Mulligan RC, Green H. Restoration of growth potential in paraclones of human keratinocytes by a viral oncogene Proceedings of the National Academy of Sciences of the United States of America. 86: 4102-4106. PMID 2471195 DOI: 10.1073/Pnas.86.11.4102  0.361
1988 Guild BC, Mulligan RC, Gros P, Housman DE. Retroviral transfer of a murine cDNA for multidrug resistance confers pleiotropic drug resistance to cells without prior drug selection. Proceedings of the National Academy of Sciences of the United States of America. 85: 1595-9. PMID 3422751 DOI: 10.1073/Pnas.85.5.1595  0.309
1988 Guild BC, Finer MH, Housman DE, Mulligan RC. Development of retrovirus vectors useful for expressing genes in cultured murine embryonal cells and hematopoietic cells in vivo. Journal of Virology. 62: 3795-801. PMID 3418785 DOI: 10.1128/Jvi.62.10.3795-3801.1988  0.422
1988 Danos O, Mulligan RC. Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges. Proceedings of the National Academy of Sciences of the United States of America. 85: 6460-4. PMID 3413107 DOI: 10.1073/Pnas.85.17.6460  0.36
1988 Collins MK, Downward J, Miyajima A, Maruyama K, Arai K, Mulligan RC. Transfer of functional EGF receptors to an IL3-dependent cell line. Journal of Cellular Physiology. 137: 293-8. PMID 3263970 DOI: 10.1002/Jcp.1041370212  0.339
1988 Hartman SC, Mulligan RC. Two dominant-acting selectable markers for gene transfer studies in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 85: 8047-51. PMID 3054879 DOI: 10.1073/Pnas.85.21.8047  0.385
1988 Dzierzak EA, Papayannopoulou T, Mulligan RC. Lineage-specific expression of a human beta-globin gene in murine bone marrow transplant recipients reconstituted with retrovirus-transduced stem cells. Nature. 331: 35-41. PMID 2893284 DOI: 10.1038/331035A0  0.411
1988 Dostatni N, Yaniv M, Danos O, Mulligan RC. Use of retroviral vectors for mapping of splice sites in cottontail rabbit papillomavirus. The Journal of General Virology. 69: 3093-100. PMID 2848927 DOI: 10.1099/0022-1317-69-12-3093  0.32
1988 Wilson JM, Jefferson DM, Chowdhury JR, Novikoff PM, Johnston DE, Mulligan RC. Retrovirus-mediated transduction of adult hepatocytes. Proceedings of the National Academy of Sciences of the United States of America. 85: 3014-8. PMID 2834728 DOI: 10.1073/Pnas.85.9.3014  0.355
1988 Wilson JM, Johnston DE, Jefferson DM, Mulligan RC. Correction of the genetic defect in hepatocytes from the Watanabe heritable hyperlipidemic rabbit. Proceedings of the National Academy of Sciences of the United States of America. 85: 4421-5. PMID 2454468 DOI: 10.1073/Pnas.85.12.4421  0.358
1987 Morgan JR, Barrandon Y, Green H, Mulligan RC. Expression of an exogenous growth hormone gene by transplantable human epidermal cells Science. 237: 1476-1479. PMID 3629250 DOI: 10.1126/Science.3629250  0.367
1987 Stacey A, Mulligan R, Jaenisch R. Rescue of type I collagen-deficient phenotype by retroviral-vector-mediated transfer of human pro alpha 1(I) collagen gene into Mov-13 cells. Journal of Virology. 61: 2549-54. PMID 3599181 DOI: 10.1128/Jvi.61.8.2549-2554.1987  0.325
1987 Williams DA, Hsieh K, DeSilva A, Mulligan RC. Protection of bone marrow transplant recipients from lethal doses of methotrexate by the generation of methotrexate-resistant bone marrow. The Journal of Experimental Medicine. 166: 210-8. PMID 3298524 DOI: 10.1084/Jem.166.1.210  0.365
1987 Cone RD, Reilly EB, Eisen HN, Mulligan RC. Tissue-specific expression of functionally rearranged lambda 1 Ig gene through a retrovirus vector. Science (New York, N.Y.). 236: 954-7. PMID 3107128 DOI: 10.1126/Science.3107128  0.387
1987 Korman AJ, Frantz JD, Strominger JL, Mulligan RC. Expression of human class II major histocompatibility complex antigens using retrovirus vectors. Proceedings of the National Academy of Sciences of the United States of America. 84: 2150-4. PMID 3031667 DOI: 10.1073/Pnas.84.8.2150  0.363
1987 Cone RD, Weber-Benarous A, Baorto D, Mulligan RC. Regulated expression of a complete human beta-globin gene encoded by a transmissible retrovirus vector. Molecular and Cellular Biology. 7: 887-97. PMID 3029570 DOI: 10.1128/Mcb.7.2.887  0.381
1987 Schwarzbauer JE, Mulligan RC, Hynes RO. Efficient and stable expression of recombinant fibronectin polypeptides. Proceedings of the National Academy of Sciences of the United States of America. 84: 754-8. PMID 3027700 DOI: 10.1073/Pnas.84.3.754  0.353
1987 Yang Z, Korman AJ, Cooper J, Pious D, Accolla RS, Mulligan RC, Strominger JL. Expression of HLA-DR antigen in human class II mutant B-cell lines by double infection with retrovirus vectors. Molecular and Cellular Biology. 7: 3923-8. PMID 2828920 DOI: 10.1128/Mcb.7.11.3923  0.355
1987 Yamada G, Kitamura Y, Sonoda H, Harada H, Taki S, Mulligan RC, Osawa H, Diamantstein T, Yokoyama S, Taniguchi T. Retroviral expression of the human IL-2 gene in a murine T cell line results in cell growth autonomy and tumorigenicity. The Embo Journal. 6: 2705-2709. DOI: 10.1002/J.1460-2075.1987.Tb02563.X  0.315
1986 Barklis E, Mulligan RC, Jaenisch R. Chromosomal position or virus mutation permits retrovirus expression in embryonal carcinoma cells. Cell. 47: 391-9. PMID 3768959 DOI: 10.1016/0092-8674(86)90596-9  0.347
1986 Bond JF, Fridovich-Keil JL, Pillus L, Mulligan RC, Solomon F. A chicken-yeast chimeric beta-tubulin protein is incorporated into mouse microtubules in vivo. Cell. 44: 461-8. PMID 3753663 DOI: 10.1016/0092-8674(86)90467-8  0.338
1986 Williams DA, Orkin SH, Mulligan RC. Retrovirus-mediated transfer of human adenosine deaminase gene sequences into cells in culture and into murine hematopoietic cells in vivo. Proceedings of the National Academy of Sciences of the United States of America. 83: 2566-70. PMID 3458218 DOI: 10.1073/Pnas.83.8.2566  0.42
1986 Soriano P, Cone RD, Mulligan RC, Jaenisch R. Tissue-specific and ectopic expression of genes introduced into transgenic mice by retroviruses. Science (New York, N.Y.). 234: 1409-13. PMID 3024318 DOI: 10.1126/Science.3024318  0.347
1986 Jat PS, Cepko CL, Mulligan RC, Sharp PA. Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens. Molecular and Cellular Biology. 6: 1204-17. PMID 3023876 DOI: 10.1128/Mcb.6.4.1204  0.342
1986 Lemischka IR, Raulet DH, Mulligan RC. Developmental potential and dynamic behavior of hematopoietic stem cells Cell. 45: 917-927. PMID 2871944 DOI: 10.1016/0092-8674(86)90566-0  0.365
1985 Stuhlmann H, Cone R, Mulligan RC, Jaenisch R. Introduction of a selectable gene into different animal tissue by a retrovirus recombinant vector. Proceedings of the National Academy of Sciences of the United States of America. 81: 7151-5. PMID 6095271 DOI: 10.1073/Pnas.81.22.7151  0.375
1985 Roberts BE, Miller JS, Kimelman D, Cepko CL, Lemischka IR, Mulligan RC. Individual adenovirus type 5 early region 1A gene products elicit distinct alterations of cellular morphology and gene expression. Journal of Virology. 56: 404-13. PMID 4057356 DOI: 10.1128/Jvi.56.2.404-413.1985  0.388
1985 Weis JH, Reiss CS, Mulligan RC, Burakoff SJ, Seidman JG. H-2Ld antigen encoded by a recombinant retrovirus genome is expressed on the surface of infected cells. Molecular and Cellular Biology. 5: 1379-84. PMID 2993861 DOI: 10.1128/Mcb.5.6.1379  0.341
1985 Jähner D, Haase K, Mulligan R, Jaenisch R. Insertion of the bacterial gpt gene into the germ line of mice by retroviral infection. Proceedings of the National Academy of Sciences of the United States of America. 82: 6927-31. PMID 2413448 DOI: 10.1073/Pnas.82.20.6927  0.356
1984 Weis JH, Nelson DL, Przyborski MJ, Chaplin DD, Mulligan RC, Housman DE, Seidman JG. Eukaryotic chromosome transfer: linkage of the murine major histocompatibility complex to an inserted dominant selectable marker. Proceedings of the National Academy of Sciences of the United States of America. 81: 4879-83. PMID 6589632 DOI: 10.1073/Pnas.81.15.4879  0.383
1984 Cepko CL, Roberts BE, Mulligan RC. Construction and applications of a highly transmissible murine retrovirus shuttle vector. Cell. 37: 1053-62. PMID 6331674 DOI: 10.1016/0092-8674(84)90440-9  0.329
1984 Cone RD, Mulligan RC. High-efficiency gene transfer into mammalian cells: generation of helper-free recombinant retrovirus with broad mammalian host range. Proceedings of the National Academy of Sciences of the United States of America. 81: 6349-53. PMID 6093098 DOI: 10.1073/Pnas.81.20.6349  0.361
1984 Hellerman JG, Cone RC, Potts JT, Rich A, Mulligan RC, Kronenberg HM. Secretion of human parathyroid hormone from rat pituitary cells infected with a recombinant retrovirus encoding preproparathyroid hormone. Proceedings of the National Academy of Sciences of the United States of America. 81: 5340-4. PMID 6089196 DOI: 10.1073/Pnas.81.17.5340  0.366
1984 Williams DA, Lemischka IR, Nathan DG, Mulligan RC. Introduction of new genetic material into pluripotent haematopoietic stem cells of the mouse. Nature. 310: 476-80. PMID 6087158 DOI: 10.1038/310476A0  0.402
1983 Mann R, Mulligan RC, Baltimore D. Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus. Cell. 33: 153-9. PMID 6678608 DOI: 10.1016/0092-8674(83)90344-6  0.342
1981 Subramani S, Mulligan R, Berg P. Expression of the mouse dihydrofolate reductase complementary deoxyribonucleic acid in simian virus 40 vectors. Molecular and Cellular Biology. 1: 854-64. PMID 9279398 DOI: 10.1128/Mcb.1.9.854  0.313
1981 Mulligan RC, Berg P. Selection for animal cells that express the Escherichia coli gene coding for xanthine-guanine phosphoribosyltransferase. Proceedings of the National Academy of Sciences of the United States of America. 78: 2072-6. PMID 7017722 DOI: 10.1073/Pnas.78.4.2072  0.352
1981 Lee F, Mulligan R, Berg P, Ringold G. Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids. Nature. 294: 228-32. PMID 6272123 DOI: 10.1038/294228A0  0.336
1981 Mulligan RC, Berg P. Factors governing the expression of a bacterial gene in mammalian cells. Molecular and Cellular Biology. 1: 449-59. PMID 6100966 DOI: 10.1128/Mcb.1.5.449  0.303
1980 Mulligan RC, Berg P. Expression of a bacterial gene in mammalian cells. Science (New York, N.Y.). 209: 1422-7. PMID 6251549 DOI: 10.1126/Science.6251549  0.378
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