Husseini K. Manji - Publications

Affiliations: 
Laboratory of Molecular Pathophysiology and Experimental Therapeutics National Institute of Mental Health (NIMH) 

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Zarate CA, Manji HK. Protein kinase C inhibitors: Rationale for use and potential in the treatment of bipolar disorder Cns Drugs. 23: 569-582. PMID 19552485 DOI: 10.2165/00023210-200923070-00003  0.307
2008 Gould TD, O'Donnell KC, Picchini AM, Dow ER, Chen G, Manji HK. Generation and behavioral characterization of beta-catenin forebrain-specific conditional knock-out mice. Behavioural Brain Research. 189: 117-25. PMID 18299155 DOI: 10.1016/J.Bbr.2007.12.028  0.561
2008 Gould TD, O'Donnell KC, Dow ER, Du J, Chen G, Manji HK. Involvement of AMPA receptors in the antidepressant-like effects of lithium in the mouse tail suspension test and forced swim test. Neuropharmacology. 54: 577-87. PMID 18096191 DOI: 10.1016/J.Neuropharm.2007.11.002  0.597
2008 Newberg AR, Catapano LA, Zarate CA, Manji HK. Neurobiology of bipolar disorder. Expert Review of Neurotherapeutics. 8: 93-110. PMID 18088203 DOI: 10.1586/14737175.8.1.93  0.304
2008 Gould T, Kovacsics C, O'Donnell K, Dow E, Chen G, Manji H. S.20.04 Lithium responsive behavioural models: a tool for understanding atypical antipsychotic action in bipolar depression and mania European Neuropsychopharmacology. 18. DOI: 10.1016/S0924-977X(08)70191-3  0.531
2007 Gould TD, Dow ER, O'Donnell KC, Chen G, Manji HK. Targeting signal transduction pathways in the treatment of mood disorders: recent insights into the relevance of the Wnt pathway. Cns & Neurological Disorders Drug Targets. 6: 193-204. PMID 17511616 DOI: 10.2174/187152707780619308  0.622
2007 Gould NF, Holmes MK, Fantie BD, Luckenbaugh DA, Pine DS, Gould TD, Burgess N, Manji HK, Zarate CA. Performance on a virtual reality spatial memory navigation task in depressed patients. The American Journal of Psychiatry. 164: 516-9. PMID 17329478 DOI: 10.1176/Ajp.2007.164.3.516  0.555
2007 Gould TD, Einat H, O'Donnell KC, Picchini AM, Schloesser RJ, Manji HK. Beta-catenin overexpression in the mouse brain phenocopies lithium-sensitive behaviors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2173-83. PMID 17299510 DOI: 10.1038/Sj.Npp.1301338  0.555
2007 Gould TD, O'Donnell KC, Picchini AM, Manji HK. Strain differences in lithium attenuation of d-amphetamine-induced hyperlocomotion: a mouse model for the genetics of clinical response to lithium. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1321-33. PMID 17151598 DOI: 10.1038/Sj.Npp.1301254  0.552
2007 Alesci S, Rodak M, Ilias I, Zhou R, Manji HK. The genomics of mood disorders. Progress in Brain Research. 158: 129-39. PMID 17027694 DOI: 10.1016/S0079-6123(06)58006-9  0.323
2006 Machado-Vieira R, Zarate CA, Manji HK. Emerging Novel Treatments for Severe Mood Disorders Involving Cellular Plasticity Cascades. Current Psychosis & Therapeutics Reports. 4: 181-190. PMID 25620894 DOI: 10.1007/Bf02629394  0.339
2006 Gould TD, Picchini AM, Einat H, Manji HK. Targeting glycogen synthase kinase-3 in the CNS: implications for the development of new treatments for mood disorders. Current Drug Targets. 7: 1399-409. PMID 17100580 DOI: 10.2174/1389450110607011399  0.62
2006 Hasler G, Drevets WC, Gould TD, Gottesman II, Manji HK. Toward constructing an endophenotype strategy for bipolar disorders. Biological Psychiatry. 60: 93-105. PMID 16406007 DOI: 10.1016/J.Biopsych.2005.11.006  0.696
2005 Bachmann RF, Schloesser RJ, Gould TD, Manji HK. Mood stabilizers target cellular plasticity and resilience cascades: implications for the development of novel therapeutics. Molecular Neurobiology. 32: 173-202. PMID 16215281 DOI: 10.1385/Mn:32:2:173  0.638
2005 Gould TD, Manji HK. Glycogen synthase kinase-3: a putative molecular target for lithium mimetic drugs. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1223-37. PMID 15827567 DOI: 10.1038/Sj.Npp.1300731  0.59
2005 Gould TD, Manji HK. DARPP-32: A molecular switch at the nexus of reward pathway plasticity. Proceedings of the National Academy of Sciences of the United States of America. 102: 253-4. PMID 15632217 DOI: 10.1073/Pnas.0408700102  0.552
2005 Quiroz JA, Singh J, Gould TD, Denicoff KD, Zarate CA, Manji HK. Emerging experimental therapeutics for bipolar disorder: clues from the molecular pathophysiology. Molecular Psychiatry. 9: 756-76. PMID 15136795 DOI: 10.1038/Sj.Mp.4001521  0.531
2005 Gould TD, Quiroz JA, Singh J, Zarate CA, Manji HK. Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers. Molecular Psychiatry. 9: 734-55. PMID 15136794 DOI: 10.1038/Sj.Mp.4001518  0.531
2005 Yuan PX, Zhou R, Farzad N, Gould TD, Gray NA, Du J, Manji HK. Chapter 5.7 Enhancing resilience to stress: the role of signaling cascades Techniques in the Behavioral and Neural Sciences. 15: 751-771. DOI: 10.1016/S0921-0709(05)80040-9  0.58
2004 Quiroz JA, Gould TD, Manji HK. Molecular effects of lithium. Molecular Interventions. 4: 259-72. PMID 15471909 DOI: 10.1124/Mi.4.5.6  0.628
2004 Gould TD, Einat H, Bhat R, Manji HK. AR-A014418, a selective GSK-3 inhibitor, produces antidepressant-like effects in the forced swim test. The International Journal of Neuropsychopharmacology. 7: 387-90. PMID 15315719 DOI: 10.1017/S1461145704004535  0.604
2004 Hao Y, Creson T, Zhang L, Li P, Du F, Yuan P, Gould TD, Manji HK, Chen G. Mood stabilizer valproate promotes ERK pathway-dependent cortical neuronal growth and neurogenesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 6590-9. PMID 15269271 DOI: 10.1523/Jneurosci.5747-03.2004  0.601
2004 Gould TD, Manji HK. The molecular medicine revolution and psychiatry: bridging the gap between basic neuroscience research and clinical psychiatry. The Journal of Clinical Psychiatry. 65: 598-604. PMID 15163244 DOI: 10.4088/Jcp.V65N0502  0.578
2004 Gould TD, Zarate CA, Manji HK. Glycogen synthase kinase-3: a target for novel bipolar disorder treatments. The Journal of Clinical Psychiatry. 65: 10-21. PMID 14744163  0.608
2004 Einat H, Manji HK, Gould TD, Du J, Chen G. Possible involvement of the ERK signaling cascade in bipolar disorder: behavioral leads from the study of mutant mice. Drug News & Perspectives. 16: 453-63. PMID 14668941 DOI: 10.1358/DNP.2003.16.7.829357  0.531
2004 Gould TD, Chen G, Manji HK. In vivo evidence in the brain for lithium inhibition of glycogen synthase kinase-3. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 32-8. PMID 12942141 DOI: 10.1038/Sj.Npp.1300283  0.579
2004 Picchini AM, Manji HK, Gould TD. GSK-3 and neurotrophic signaling: novel targets underlying the pathophysiology and treatment of mood disorders? Drug Discovery Today: Disease Mechanisms. 1: 419-428. DOI: 10.1016/J.Ddmec.2004.11.020  0.634
2004 Yuan P, Gould TD, Gray NA, Bachmann RF, Schloesser RJ, Lan MJK, Du J, Moore GJ, Manji HK. Neurotrophic signaling cascades are major long-term targets for lithium: Clinical implications Clinical Neuroscience Research. 4: 137-153. DOI: 10.1016/J.Cnr.2004.09.006  0.632
2004 Gould TD, Zarate CA, Manji HK. Glycogen synthase kinase-3: a target for novel bipolar disorder treatments. The Journal of Clinical Psychiatry. 65: 10-21. DOI: 10.1002/0470052171.Ch7  0.608
2003 Manji HK, Quiroz JA, Payne JL, Singh J, Lopes BP, Viegas JS, Zarate CA. The underlying neurobiology of bipolar disorder. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 2: 136-46. PMID 16946919  0.304
2003 Zarate CA, Du J, Quiroz J, Gray NA, Denicoff KD, Singh J, Charney DS, Manji HK. Regulation of cellular plasticity cascades in the pathophysiology and treatment of mood disorders: role of the glutamatergic system. Annals of the New York Academy of Sciences. 1003: 273-91. PMID 14684452 DOI: 10.1196/Annals.1300.017  0.31
2003 Manji HK, Gottesman II, Gould TD. Signal transduction and genes-to-behaviors pathways in psychiatric diseases. Science's Stke : Signal Transduction Knowledge Environment. 2003: pe49. PMID 14600293 DOI: 10.1126/Stke.2003.207.Pe49  0.677
2003 Einat H, Yuan P, Gould TD, Li J, Du J, Zhang L, Manji HK, Chen G. The role of the extracellular signal-regulated kinase signaling pathway in mood modulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 7311-6. PMID 12917364 DOI: 10.1523/Jneurosci.23-19-07311.2003  0.597
2003 Gould TD, Gray NA, Manji HK. Effects of a glycogen synthase kinase-3 inhibitor, lithium, in adenomatous polyposis coli mutant mice. Pharmacological Research. 48: 49-53. PMID 12770514 DOI: 10.1016/S1043-6618(03)00096-3  0.582
2003 Manji HK, Quiroz JA, Sporn J, Payne JL, Denicoff K, A Gray N, Zarate CA, Charney DS. Enhancing neuronal plasticity and cellular resilience to develop novel, improved therapeutics for difficult-to-treat depression. Biological Psychiatry. 53: 707-42. PMID 12706957 DOI: 10.1016/S0006-3223(03)00117-3  0.307
2003 Li J, Gould TD, Yuan P, Manji HK, Chen G. Post-mortem interval effects on the phosphorylation of signaling proteins. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1017-25. PMID 12637955 DOI: 10.1038/Sj.Npp.1300112  0.564
2002 Gould TD, Chen G, Manji HK. Mood stabilizer psychopharmacology. Clinical Neuroscience Research. 2: 193-212. PMID 22707923 DOI: 10.1016/S1566-2772(02)00044-0  0.629
2002 Gould TD, Manji HK. The Wnt signaling pathway in bipolar disorder. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 8: 497-511. PMID 12374432 DOI: 10.1177/107385802237176  0.607
2002 Nestler EJ, Gould E, Manji H, Buncan M, Duman RS, Greshenfeld HK, Hen R, Koester S, Lederhendler I, Meaney M, Robbins T, Winsky L, Zalcman S. Preclinical models: status of basic research in depression. Biological Psychiatry. 52: 503-28. PMID 12361666 DOI: 10.1016/S0006-3223(02)01405-1  0.321
2002 Gould TD, Manji HK. Signaling networks in the pathophysiology and treatment of mood disorders. Journal of Psychosomatic Research. 53: 687-97. PMID 12169343 DOI: 10.1016/S0022-3999(02)00426-9  0.614
2002 Lenox RH, Gould TD, Manji HK. Endophenotypes in bipolar disorder. American Journal of Medical Genetics. 114: 391-406. PMID 11992561 DOI: 10.1002/Ajmg.10360  0.59
2000 Manji HK, Moore GJ, Rajkowska G, Chen G. Neuroplasticity and cellular resilience in mood disorders. Molecular Psychiatry. 5: 578-93. PMID 11126389 DOI: 10.1038/Sj.Mp.4000811  0.313
2000 Manji HK, Moore GJ, Chen G. Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic-depressive illness. Biological Psychiatry. 48: 740-54. PMID 11063971 DOI: 10.1016/S0006-3223(00)00979-3  0.313
1998 Manji HK, Lenox RH. Lithium: a molecular transducer of mood-stabilization in the treatment of bipolar disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 19: 161-6. PMID 9741960 DOI: 10.1016/S0893-133X(98)00021-9  0.317
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