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Baldomero M. Olivera - Publications

Affiliations: 
Biology University of Utah, Salt Lake City, UT 
Area:
characterization of venom components in venomous marine snails, in particular, those belonging to the genus Conus, and the identification of their molecular targets, and exploration of potential biomedical applications
Website:
http://neuroscience.med.utah.edu/Faculty/Olivera.html

249 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Paguigan ND, Yan Y, Karthikeyan M, Chase K, Carter J, Leavitt LS, Lim AL, Lin Z, Memon T, Christensen S, Bentzen BH, Schmitt N, Reilly CA, Teichert RW, Raghuraman S, ... Olivera BM, et al. The Tunicate Metabolite 2-(3,5-Diiodo-4-methoxyphenyl)ethan-1-amine Targets Ion Channels of Vertebrate Sensory Neurons. Acs Chemical Biology. PMID 34423964 DOI: 10.1021/acschembio.1c00328  0.767
2021 Paguigan ND, Tun JO, Leavitt LS, Lin Z, Chase K, Dowell C, Deering-Rice CE, Lim AL, Karthikeyan M, Hughen RW, Zhang J, Peterson RT, Reilly CA, Light AR, Raghuraman S, ... ... Olivera BM, et al. Nicotinic Acetylcholine Receptor Partial Antagonist Polyamides from Tunicates and Their Predatory Sea Slugs. Acs Chemical Neuroscience. PMID 34213884 DOI: 10.1021/acschemneuro.1c00345  0.601
2021 Niu C, Leavitt LS, Lin Z, Paguigan ND, Sun L, Zhang J, Torres JP, Raghuraman S, Chase K, Cadeddu R, Karthikeyan M, Bortolato M, Reilly CA, Hughen RW, Light AR, ... Olivera BM, et al. Neuroactive Type-A γ-Aminobutyric Acid Receptor Allosteric Modulator Steroids from the Hypobranchial Gland of Marine Mollusk, . Journal of Medicinal Chemistry. PMID 33949869 DOI: 10.1021/acs.jmedchem.1c00562  0.579
2021 Bosse GD, Urcino C, Watkins M, Flórez Salcedo P, Kozel S, Chase K, Cabang A, Espino SS, Safavi-Hemami H, Raghuraman S, Olivera BM, Peterson RT, Gajewiak J. Discovery of a Potent Conorfamide from Using a Novel Zebrafish Larvae Assay. Journal of Natural Products. PMID 33764053 DOI: 10.1021/acs.jnatprod.0c01297  0.567
2020 Raghuraman S, Xie JY, Giacobassi MJ, Tun JO, Chase K, Lu D, Teichert RW, Porreca F, Olivera BM. Chronicling changes in the somatosensory neurons after peripheral nerve injury. Proceedings of the National Academy of Sciences of the United States of America. PMID 33020310 DOI: 10.1073/pnas.1922618117  0.76
2020 Chua VM, Gajewiak J, Watkins M, Espino SS, Ramiro IBL, Omaga CA, Imperial JS, Carpio LPD, Fedosov A, Safavi-Hemami H, Salvador-Reyes LA, Olivera BM, Concepcion GP. Purification and Characterization of the Pink-Floyd Drillipeptide, a Bioactive Venom Peptide from (Gastropoda: Conoidea: Drilliidae). Toxins. 12. PMID 32784699 DOI: 10.3390/toxins12080508  0.438
2020 Inagaki RT, Raghuraman S, Chase K, Steele T, Zornik E, Olivera BM, Yamaguchi A. Molecular characterization of frog vocal neurons using constellation pharmacology. Journal of Neurophysiology. PMID 32374212 DOI: 10.1152/Jn.00105.2020  0.635
2020 Lu A, Watkins M, Li Q, Robinson SD, Concepcion GP, Yandell M, Weng Z, Olivera BM, Safavi-Hemami H, Fedosov AE. Transcriptomic profiling reveals extraordinary diversity of venom peptides in unexplored predatory gastropods of the genus Clavus. Genome Biology and Evolution. PMID 32333764 DOI: 10.1093/Gbe/Evaa083  0.382
2020 Rybin MJ, O'Brien H, Ramiro IBL, Azam L, McIntosh JM, Olivera BM, Safavi-Hemami H, Yoshikami D. αM-Conotoxin MIIIJ Blocks Nicotinic Acetylcholine Receptors at Neuromuscular Junctions of Frog and Fish. Toxins. 12. PMID 32245200 DOI: 10.3390/toxins12030197  0.344
2020 Torres JP, Lin Z, Fenton DS, Leavitt LU, Niu C, Lam PY, Robes JM, Peterson RT, Concepcion GP, Haygood MG, Olivera BM, Schmidt EW. Boholamide A, an APD-Class, Hypoxia-Selective Cyclodepsipeptide. Journal of Natural Products. PMID 32186874 DOI: 10.1021/Acs.Jnatprod.0C00038  0.316
2020 Giacobassi MJ, Leavitt LS, Raghuraman S, Alluri R, Chase K, Finol-Urdaneta RK, Terlau H, Teichert RW, Olivera BM. An integrative approach to the facile functional classification of dorsal root ganglion neuronal subclasses. Proceedings of the National Academy of Sciences of the United States of America. PMID 32079727 DOI: 10.1073/Pnas.1911382117  0.772
2019 Neves JLB, Imperial JS, Morgenstern D, Ueberheide B, Gajewiak J, Antunes A, Robinson SD, Espino S, Watkins M, Vasconcelos V, Olivera BM. Characterization of the First Conotoxin from , a Vermivorous Cone Snail from the Cabo Verde Archipelago. Marine Drugs. 17. PMID 31344776 DOI: 10.3390/Md17080432  0.414
2019 van Hout M, Valdes A, Christensen SB, Tran PT, Watkins M, Gajewiak J, Jensen AA, Olivera BM, McIntosh JM. α-Conotoxin VnIB from Conus ventricosus is a potent and selective antagonist of α6β4* nicotinic acetylcholine receptors. Neuropharmacology. 107691. PMID 31255696 DOI: 10.1016/j.neuropharm.2019.107691  0.369
2019 Memon T, Yarishkin O, Reilly CA, Krizaj D, Olivera BM, Teichert RW. trans-Anethole of Fennel oil is a selective and non-electrophilic agonist of the TRPA1 ion channel. Molecular Pharmacology. PMID 30679204 DOI: 10.1124/Mol.118.114561  0.713
2018 Cordeiro S, Finol-Urdaneta RK, Köpfer D, Markushina A, Song J, French RJ, Kopec W, de Groot BL, Giacobassi MJ, Leavitt LS, Raghuraman S, Teichert RW, Olivera BM, Terlau H. Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric K1 channels. Proceedings of the National Academy of Sciences of the United States of America. PMID 30593566 DOI: 10.1073/Pnas.1813161116  0.77
2018 O'Brien H, Kanemura S, Okumura M, Baskin RP, Bandyopadhyay PK, Olivera BM, Ellgaard L, Inaba K, Safavi-Hemami H. Ero1-Mediated Reoxidation of Protein Disulfide Isomerase Accelerates the Folding of Cone Snail Toxins. International Journal of Molecular Sciences. 19. PMID 30384459 DOI: 10.3390/ijms19113418  0.383
2018 Espino SS, Robinson SD, Safavi-Hemami H, Gajewiak J, Yang W, Olivera BM, Liu Q. Conopeptides promote itch through human itch receptor hMgprX1. Toxicon : Official Journal of the International Society On Toxinology. PMID 30243794 DOI: 10.1016/J.Toxicon.2018.09.002  0.432
2017 Omaga CA, Carpio LD, Imperial JS, Daly NL, Gajewiak J, Flores MS, Espino SS, Christensen S, Filchakova OM, López-Vera E, Raghuraman S, Olivera BM, Concepcion GP. Structure and Biological Activity of a Turripeptide from Unedogemmula bisaya Venom. Biochemistry. PMID 29090914 DOI: 10.1021/Acs.Biochem.7B00485  0.628
2017 Torres JP, Tianero MD, Robes JMD, Kwan JC, Biggs JS, Concepcion GP, Olivera BM, Haygood MG, Schmidt EW. Stenotrophomonas-like bacteria are widespread symbionts in cone snail venom ducts. Applied and Environmental Microbiology. PMID 28986377 DOI: 10.1128/Aem.01418-17  0.338
2017 Lin Z, Smith MD, Concepcion GP, Haygood MG, Olivera BM, Light A, Schmidt EW. Modulating the Serotonin Receptor Spectrum of Pulicatin Natural Products. Journal of Natural Products. PMID 28745513 DOI: 10.1021/Acs.Jnatprod.7B00317  0.335
2017 Olivera BM, Raghuraman S, Schmidt EW, Safavi-Hemami H. Linking neuroethology to the chemical biology of natural products: interactions between cone snails and their fish prey, a case study. Journal of Comparative Physiology. a, Neuroethology, Sensory, Neural, and Behavioral Physiology. PMID 28551870 DOI: 10.1007/S00359-017-1183-7  0.569
2017 Memon T, Chase K, Leavitt LS, Olivera BM, Teichert RW. TRPA1 expression levels and excitability brake by KV channels influence cold sensitivity of TRPA1-expressing neurons. Neuroscience. PMID 28408328 DOI: 10.1016/J.Neuroscience.2017.04.001  0.712
2017 Drane SB, Robinson SD, MacRaild CA, Chhabra S, Chittoor B, Morales RA, Leung EW, Belgi A, Espino SS, Olivera BM, Robinson AJ, Chalmers DK, Norton RS. Structure and activity of contryphan-Vc2: Importance of the D-amino acid residue. Toxicon : Official Journal of the International Society On Toxinology. PMID 28216409 DOI: 10.1016/j.toxicon.2017.02.012  0.375
2016 Green BR, Olivera BM. Venom Peptides From Cone Snails: Pharmacological Probes for Voltage-Gated Sodium Channels. Current Topics in Membranes. 78: 65-86. PMID 27586281 DOI: 10.1016/bs.ctm.2016.07.001  0.422
2016 Safavi-Hemami H, Li Q, Jackson RL, Song AS, Boomsma W, Bandyopadhyay PK, Gruber CW, Purcell AW, Yandell M, Olivera BM, Ellgaard L. Rapid expansion of the protein disulfide isomerase gene family facilitates the folding of venom peptides. Proceedings of the National Academy of Sciences of the United States of America. PMID 26957604 DOI: 10.1073/Pnas.1525790113  0.326
2016 Espino SS, Dilanyan T, Imperial JS, Aguilar MB, Teichert RW, Bandyopadhyay P, Olivera BM. Glycine-rich Conotoxins from the Virgiconus clade. Toxicon : Official Journal of the International Society On Toxinology. PMID 26851775 DOI: 10.1016/J.Toxicon.2016.02.001  0.733
2016 Tianero MD, Pierce E, Raghuraman S, Sardar D, McIntosh JA, Heemstra JR, Schonrock Z, Covington BC, Maschek JA, Cox JE, Bachmann BO, Olivera BM, Ruffner DE, Schmidt EW. Metabolic model for diversity-generating biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 26831074 DOI: 10.1073/Pnas.1525438113  0.556
2015 Curtice KJ, Leavitt LS, Chase K, Raghuraman S, Horvath MP, Olivera BM, Teichert RW. Classifying neuronal subclasses of the cerebellum through constellation pharmacology. Journal of Neurophysiology. jn.00894.2015. PMID 26581874 DOI: 10.1152/Jn.00894.2015  0.792
2015 Barghi N, Concepcion GP, Olivera BM, Lluisma AO. Structural features of conopeptide genes inferred from partial sequences of the Conus tribblei genome. Molecular Genetics and Genomics : Mgg. PMID 26423067 DOI: 10.1007/S00438-015-1119-2  0.31
2015 Neves JL, Lin Z, Imperial JS, Antunes A, Vasconcelos V, Olivera BM, Schmidt EW. Small Molecules in the Cone Snail Arsenal. Organic Letters. PMID 26421741 DOI: 10.1021/Acs.Orglett.5B02389  0.325
2015 Christensen SB, Bandyopadhyay PK, Olivera BM, McIntosh JM. αS-conotoxin GVIIIB potently and selectively blocks α9α10 nicotinic acetylcholine receptors. Biochemical Pharmacology. PMID 26074268 DOI: 10.1016/j.bcp.2015.06.007  0.397
2015 Barghi N, Concepcion GP, Olivera BM, Lluisma AO. Comparison of the Venom Peptides and Their Expression in Closely Related Conus Species: Insights into Adaptive Post-speciation Evolution of Conus Exogenomes. Genome Biology and Evolution. 7: 1797-814. PMID 26047846 DOI: 10.1093/Gbe/Evv109  0.343
2015 Zhang MM, Gajewiak J, Azam L, Bulaj G, Olivera BM, Yoshikami D. Probing the Redox States of Sodium Channel Cysteines at the Binding Site of μO§-Conotoxin GVIIJ. Biochemistry. 54: 3911-20. PMID 26039939 DOI: 10.1021/Acs.Biochem.5B00390  0.385
2015 Aman JW, Imperial JS, Ueberheide B, Zhang MM, Aguilar M, Taylor D, Watkins M, Yoshikami D, Showers-Corneli P, Safavi-Hemami H, Biggs J, Teichert RW, Olivera BM. Insights into the origins of fish hunting in venomous cone snails from studies of Conus tessulatus. Proceedings of the National Academy of Sciences of the United States of America. 112: 5087-92. PMID 25848010 DOI: 10.1073/Pnas.1424435112  0.731
2015 Lee HK, Zhang L, Smith MD, Walewska A, Vellore NA, Baron R, McIntosh JM, White HS, Olivera BM, Bulaj G. A marine analgesic peptide, Contulakin-G, and neurotensin are distinct agonists for neurotensin receptors: uncovering structural determinants of desensitization properties. Frontiers in Pharmacology. 6: 11. PMID 25713532 DOI: 10.3389/Fphar.2015.00011  0.372
2015 Wilson MJ, Zhang MM, Gajewiak J, Azam L, Rivier JE, Olivera BM, Yoshikami D. Α- and β-subunit composition of voltage-gated sodium channels investigated with μ-conotoxins and the recently discovered μO§-conotoxin GVIIJ. Journal of Neurophysiology. 113: 2289-301. PMID 25632083 DOI: 10.1152/jn.01004.2014  0.323
2015 Teichert RW, Schmidt EW, Olivera BM. Constellation pharmacology: a new paradigm for drug discovery. Annual Review of Pharmacology and Toxicology. 55: 573-89. PMID 25562646 DOI: 10.1146/Annurev-Pharmtox-010814-124551  0.681
2015 Robinson SD, Safavi-Hemami H, Raghuraman S, Imperial JS, Papenfuss AT, Teichert RW, Purcell AW, Olivera BM, Norton RS. Discovery by proteogenomics and characterization of an RF-amide neuropeptide from cone snail venom. Journal of Proteomics. 114: 38-47. PMID 25464369 DOI: 10.1016/J.Jprot.2014.11.003  0.796
2015 Barghi N, Concepcion GP, Olivera BM, Lluisma AO. High conopeptide diversity in Conus tribblei revealed through analysis of venom duct transcriptome using two high-throughput sequencing platforms. Marine Biotechnology (New York, N.Y.). 17: 81-98. PMID 25117477 DOI: 10.1007/S10126-014-9595-7  0.369
2015 Kalia J, Milescu M, Salvatierra J, Wagner J, Klint JK, King GF, Olivera BM, Bosmans F. From foe to friend: using animal toxins to investigate ion channel function. Journal of Molecular Biology. 427: 158-75. PMID 25088688 DOI: 10.1016/J.Jmb.2014.07.027  0.316
2015 Teichert RW, Olivera BM, Michael McIntosh J, Bulaj G, Horvath MP. The molecular diversity of conoidean venom peptides and their targets: From basic research to therapeutic applications Rsc Drug Discovery Series. 2015: 163-203.  0.688
2014 Olivera BM, Showers Corneli P, Watkins M, Fedosov A. Biodiversity of cone snails and other venomous marine gastropods: evolutionary success through neuropharmacology. Annual Review of Animal Biosciences. 2: 487-513. PMID 25384153 DOI: 10.1146/Annurev-Animal-022513-114124  0.309
2014 Imperial JS, Cabang AB, Song J, Raghuraman S, Gajewiak J, Watkins M, Showers-Corneli P, Fedosov A, Concepcion GP, Terlau H, Teichert RW, Olivera BM. A family of excitatory peptide toxins from venomous crassispirine snails: using Constellation Pharmacology to assess bioactivity. Toxicon : Official Journal of the International Society On Toxinology. 89: 45-54. PMID 24997406 DOI: 10.1016/J.Toxicon.2014.06.014  0.8
2014 Green BR, Zhang MM, Chhabra S, Robinson SD, Wilson MJ, Redding A, Olivera BM, Yoshikami D, Bulaj G, Norton RS. Interactions of disulfide-deficient selenocysteine analogs of μ-conotoxin BuIIIB with the α-subunit of the voltage-gated sodium channel subtype 1.3. The Febs Journal. 281: 2885-98. PMID 24814369 DOI: 10.1111/Febs.12835  0.381
2014 Lin Z, Zachariah MM, Marett L, Hughen RW, Teichert RW, Concepcion GP, Haygood MG, Olivera BM, Light AR, Schmidt EW. Griseorhodins D-F, neuroactive intermediates and end products of post-PKS tailoring modification in Griseorhodin biosynthesis. Journal of Natural Products. 77: 1224-30. PMID 24786728 DOI: 10.1021/Np500155D  0.676
2014 Gilchrist J, Olivera BM, Bosmans F. Animal toxins influence voltage-gated sodium channel function. Handbook of Experimental Pharmacology. 221: 203-29. PMID 24737238 DOI: 10.1007/978-3-642-41588-3_10  0.335
2014 Raghuraman S, Garcia AJ, Anderson TM, Twede VD, Curtice KJ, Chase K, Ramirez JM, Olivera BM, Teichert RW. Defining modulatory inputs into CNS neuronal subclasses by functional pharmacological profiling. Proceedings of the National Academy of Sciences of the United States of America. 111: 6449-54. PMID 24733934 DOI: 10.1073/Pnas.1404421111  0.779
2014 Platt RJ, Curtice KJ, Twede VD, Watkins M, Gruszczy?ski P, Bulaj G, Horvath MP, Olivera BM. From molecular phylogeny towards differentiating pharmacology for NMDA receptor subtypes. Toxicon : Official Journal of the International Society On Toxinology. 81: 67-79. PMID 24508768 DOI: 10.1016/J.Toxicon.2014.01.016  0.801
2014 Gajewiak J, Azam L, Imperial J, Walewska A, Green BR, Bandyopadhyay PK, Raghuraman S, Ueberheide B, Bern M, Zhou HM, Minassian NA, Hagan RH, Flinspach M, Liu Y, Bulaj G, ... ... Olivera BM, et al. A disulfide tether stabilizes the block of sodium channels by the conotoxin μO§-GVIIJ. Proceedings of the National Academy of Sciences of the United States of America. 111: 2758-63. PMID 24497506 DOI: 10.1073/Pnas.1324189111  0.663
2014 Safavi-Hemami H, Hu H, Gorasia DG, Bandyopadhyay PK, Veith PD, Young ND, Reynolds EC, Yandell M, Olivera BM, Purcell AW. Combined proteomic and transcriptomic interrogation of the venom gland of Conus geographus uncovers novel components and functional compartmentalization. Molecular & Cellular Proteomics : McP. 13: 938-53. PMID 24478445 DOI: 10.1074/Mcp.M113.031351  0.319
2014 Teichert RW, Memon T, Aman JW, Olivera BM. Using constellation pharmacology to define comprehensively a somatosensory neuronal subclass. Proceedings of the National Academy of Sciences of the United States of America. 111: 2319-24. PMID 24469798 DOI: 10.1073/Pnas.1324019111  0.719
2013 Smith NJ, Hone AJ, Memon T, Bossi S, Smith TE, McIntosh JM, Olivera BM, Teichert RW. Comparative functional expression of nAChR subtypes in rodent DRG neurons. Frontiers in Cellular Neuroscience. 7: 225. PMID 24348328 DOI: 10.3389/Fncel.2013.00225  0.709
2013 Ul-Hasan S, Burgess DM, Gajewiak J, Li Q, Hu H, Yandell M, Olivera BM, Bandyopadhyay PK. Characterization of the peptidylglycine α-amidating monooxygenase (PAM) from the venom ducts of neogastropods, Conus bullatus and Conus geographus. Toxicon : Official Journal of the International Society On Toxinology. 74: 215-24. PMID 23994590 DOI: 10.1016/J.Toxicon.2013.08.054  0.376
2013 Kuang Z, Zhang MM, Gupta K, Gajewiak J, Gulyas J, Balaram P, Rivier JE, Olivera BM, Yoshikami D, Bulaj G, Norton RS. Mammalian neuronal sodium channel blocker μ-conotoxin BuIIIB has a structured N-terminus that influences potency. Acs Chemical Biology. 8: 1344-51. PMID 23557677 DOI: 10.1021/Cb300674X  0.398
2013 Aguilar MB, Zugasti-Cruz A, Falcón A, Batista CV, Olivera BM, de la Cotera EP. A novel arrangement of Cys residues in a paralytic peptide of Conus cancellatus (jr. syn.: Conus austini), a worm-hunting snail from the Gulf of Mexico. Peptides. 41: 38-44. PMID 23474143 DOI: 10.1016/j.peptides.2013.02.016  0.384
2013 Lin Z, Torres JP, Ammon MA, Marett L, Teichert RW, Reilly CA, Kwan JC, Hughen RW, Flores M, Tianero MD, Peraud O, Cox JE, Light AR, Villaraza AJ, Haygood MG, ... ... Olivera BM, et al. A bacterial source for mollusk pyrone polyketides. Chemistry & Biology. 20: 73-81. PMID 23352141 DOI: 10.1016/J.Chembiol.2012.10.019  0.673
2013 Zhang MM, Wilson MJ, Gajewiak J, Rivier JE, Bulaj G, Olivera BM, Yoshikami D. Pharmacological fractionation of tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons by μ-conotoxins. British Journal of Pharmacology. 169: 102-14. PMID 23351163 DOI: 10.1111/Bph.12119  0.337
2013 Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, ... ... Olivera BM, et al. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Natural Product Reports. 30: 108-60. PMID 23165928 DOI: 10.1039/C2Np20085F  0.331
2013 Zhang MM, Wilson MJ, Azam L, Gajewiak J, Rivier JE, Bulaj G, Olivera BM, Yoshikami D. Co-expression of Na(V)β subunits alters the kinetics of inhibition of voltage-gated sodium channels by pore-blocking μ-conotoxins. British Journal of Pharmacology. 168: 1597-610. PMID 23146020 DOI: 10.1111/Bph.12051  0.351
2013 Arnison PG, Bibb MJ, Bierbaum G, Bowers AA, Bugni TS, Bulaj G, Camarero JA, Campopiano DJ, Challis GL, Clardy J, Cotter PD, Craik DJ, Dawson M, Dittmann E, Donadio S, ... ... Olivera BM, et al. Erratum: Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature (Natural Product Reports (2013) 30 (108-160) DOI:10.1039/C2NP20085F) Natural Product Reports. 30: 1568-1568. DOI: 10.1039/C3Np90040A  0.312
2012 Olivera BM, Watkins M, Bandyopadhyay P, Imperial JS, de la Cotera EP, Aguilar MB, Vera EL, Concepcion GP, Lluisma A. Adaptive radiation of venomous marine snail lineages and the accelerated evolution of venom peptide genes. Annals of the New York Academy of Sciences. 1267: 61-70. PMID 22954218 DOI: 10.1111/J.1749-6632.2012.06603.X  0.331
2012 Safavi-Hemami H, Gorasia DG, Steiner AM, Williamson NA, Karas JA, Gajewiak J, Olivera BM, Bulaj G, Purcell AW. Modulation of conotoxin structure and function is achieved through a multienzyme complex in the venom glands of cone snails. The Journal of Biological Chemistry. 287: 34288-303. PMID 22891240 DOI: 10.1074/Jbc.M112.366781  0.337
2012 Gowd KH, Blais KD, Elmslie KS, Steiner AM, Olivera BM, Bulaj G. Dissecting a role of evolutionary-conserved but noncritical disulfide bridges in cysteine-rich peptides using ω-conotoxin GVIA and its selenocysteine analogs. Biopolymers. 98: 212-23. PMID 22782563 DOI: 10.1002/Bip.22047  0.382
2012 Teichert RW, Raghuraman S, Memon T, Cox JL, Foulkes T, Rivier JE, Olivera BM. Characterization of two neuronal subclasses through constellation pharmacology. Proceedings of the National Academy of Sciences of the United States of America. 109: 12758-63. PMID 22778416 DOI: 10.1073/Pnas.1209759109  0.787
2012 Puillandre N, Koua D, Favreau P, Olivera BM, Stöcklin R. Molecular phylogeny, classification and evolution of conopeptides. Journal of Molecular Evolution. 74: 297-309. PMID 22760645 DOI: 10.1007/s00239-012-9507-2  0.347
2012 Hu H, Bandyopadhyay PK, Olivera BM, Yandell M. Elucidation of the molecular envenomation strategy of the cone snail Conus geographus through transcriptome sequencing of its venom duct. Bmc Genomics. 13: 284. PMID 22742208 DOI: 10.1186/1471-2164-13-284  0.409
2012 Singer HM, Erhardt M, Steiner AM, Zhang MM, Yoshikami D, Bulaj G, Olivera BM, Hughes KT. Selective purification of recombinant neuroactive peptides using the flagellar type III secretion system. Mbio. 3. PMID 22647788 DOI: 10.1128/Mbio.00115-12  0.353
2012 Gowd KH, Han TS, Twede V, Gajewiak J, Smith MD, Watkins M, Platt RJ, Toledo G, White HS, Olivera BM, Bulaj G. Conantokins derived from the Asprella clade impart conRl-B, an N-methyl d-aspartate receptor antagonist with a unique selectivity profile for NR2B subunits. Biochemistry. 51: 4685-92. PMID 22594498 DOI: 10.1021/Bi300055N  0.791
2012 Platt RJ, Han TS, Green BR, Smith MD, Skalicky J, Gruszczynski P, White HS, Olivera B, Bulaj G, Gajewiak J. Stapling mimics noncovalent interactions of γ-carboxyglutamates in conantokins, peptidic antagonists of N-methyl-D-aspartic acid receptors. The Journal of Biological Chemistry. 287: 20727-36. PMID 22518838 DOI: 10.1074/Jbc.M112.350462  0.765
2012 Steiner AM, Woycechowsky KJ, Olivera BM, Bulaj G. Reagentless oxidative folding of disulfide-rich peptides catalyzed by an intramolecular diselenide. Angewandte Chemie (International Ed. in English). 51: 5580-4. PMID 22454362 DOI: 10.1002/Anie.201200062  0.309
2012 Lin Z, Flores M, Forteza I, Henriksen NM, Concepcion GP, Rosenberg G, Haygood MG, Olivera BM, Light AR, Cheatham TE, Schmidt EW. Totopotensamides, polyketide-cyclic peptide hybrids from a mollusk-associated bacterium Streptomyces sp. Journal of Natural Products. 75: 644-9. PMID 22439622 DOI: 10.1021/Np200886X  0.332
2012 Lluisma AO, Milash BA, Moore B, Olivera BM, Bandyopadhyay PK. Novel venom peptides from the cone snail Conus pulicarius discovered through next-generation sequencing of its venom duct transcriptome. Marine Genomics. 5: 43-51. PMID 22325721 DOI: 10.1016/J.Margen.2011.09.002  0.357
2012 Teichert RW, Smith NJ, Raghuraman S, Yoshikami D, Light AR, Olivera BM. Functional profiling of neurons through cellular neuropharmacology. Proceedings of the National Academy of Sciences of the United States of America. 109: 1388-95. PMID 22307590 DOI: 10.1073/Pnas.1118833109  0.782
2012 Teichert RW, Olivera BM. Reply to Voets et al.: Constellation pharmacology is poised to answer scientific questions Proceedings of the National Academy of Sciences of the United States of America. 109: E3339. DOI: 10.1073/Pnas.1215574109  0.692
2011 Olivera BM, Teichert RW. Neuroscience: chemical ecology of pain. Nature. 479: 306-7. PMID 22094687 DOI: 10.1038/479306A  0.676
2011 Cabang AB, Imperial JS, Gajewiak J, Watkins M, Corneli PS, Olivera BM, Concepcion GP. Characterization of a venom peptide from a crassispirid gastropod. Toxicon : Official Journal of the International Society On Toxinology. 58: 672-80. PMID 21939682 DOI: 10.1016/J.Toxicon.2011.09.001  0.388
2011 Wilson MJ, Yoshikami D, Azam L, Gajewiak J, Olivera BM, Bulaj G, Zhang MM. μ-Conotoxins that differentially block sodium channels NaV1.1 through 1.8 identify those responsible for action potentials in sciatic nerve. Proceedings of the National Academy of Sciences of the United States of America. 108: 10302-7. PMID 21652775 DOI: 10.1073/Pnas.1107027108  0.318
2011 Wilson MJ, Zhang MM, Azam L, Olivera BM, Bulaj G, Yoshikami D. Navβ subunits modulate the inhibition of Nav1.8 by the analgesic gating modifier μO-conotoxin MrVIB. The Journal of Pharmacology and Experimental Therapeutics. 338: 687-93. PMID 21586605 DOI: 10.1124/Jpet.110.178343  0.339
2011 Lin Z, Reilly CA, Antemano R, Hughen RW, Marett L, Concepcion GP, Haygood MG, Olivera BM, Light A, Schmidt EW. Nobilamides A-H, long-acting transient receptor potential vanilloid-1 (TRPV1) antagonists from mollusk-associated bacteria. Journal of Medicinal Chemistry. 54: 3746-55. PMID 21524089 DOI: 10.1021/Jm101621U  0.334
2011 Hu H, Bandyopadhyay PK, Olivera BM, Yandell M. Characterization of the Conus bullatus genome and its venom-duct transcriptome. Bmc Genomics. 12: 60. PMID 21266071 DOI: 10.1186/1471-2164-12-60  0.34
2011 Finol-Urdaneta RK, Becker S, Olivera BM, Terlau H, French RJ. Discrimination Among Heteromeric Potassium Channels by Pore-Blocking Conotoxins Biophysical Journal. 100: 566a. DOI: 10.1016/j.bpj.2010.12.3284  0.372
2010 Teichert RW, Olivera BM. Natural products and ion channel pharmacology. Future Medicinal Chemistry. 2: 731-44. PMID 21426200 DOI: 10.4155/Fmc.10.31  0.695
2010 Lin Z, Antemano RR, Hughen RW, Tianero MD, Peraud O, Haygood MG, Concepcion GP, Olivera BM, Light A, Schmidt EW. Pulicatins A-E, neuroactive thiazoline metabolites from cone snail-associated bacteria. Journal of Natural Products. 73: 1922-6. PMID 21028889 DOI: 10.1021/Np100588C  0.315
2010 Han TS, Zhang MM, Gowd KH, Walewska A, Yoshikami D, Olivera BM, Bulaj G. Disulfide-Depleted Selenoconopeptides: a Minimalist Strategy to Oxidative Folding of Cysteine-Rich Peptides. Acs Medicinal Chemistry Letters. 1: 140-144. PMID 20676359 DOI: 10.1021/Ml900017Q  0.397
2010 Gowd KH, Watkins M, Twede VD, Bulaj GW, Olivera BM. Characterization of conantokin Rl-A: molecular phylogeny as structure/function study. Journal of Peptide Science : An Official Publication of the European Peptide Society. 16: 375-82. PMID 20572027 DOI: 10.1002/Psc.1249  0.818
2010 Zhang MM, Han TS, Olivera BM, Bulaj G, Yoshikami D. μ-conotoxin KIIIA derivatives with divergent affinities versus efficacies in blocking voltage-gated sodium channels. Biochemistry. 49: 4804-12. PMID 20459109 DOI: 10.1021/Bi100207K  0.357
2010 Zhang MM, Gruszczynski P, Walewska A, Bulaj G, Olivera BM, Yoshikami D. Cooccupancy of the outer vestibule of voltage-gated sodium channels by micro-conotoxin KIIIA and saxitoxin or tetrodotoxin. Journal of Neurophysiology. 104: 88-97. PMID 20410356 DOI: 10.1152/Jn.00145.2010  0.372
2010 Biggs JS, Watkins M, Puillandre N, Ownby JP, Lopez-Vera E, Christensen S, Moreno KJ, Bernaldez J, Licea-Navarro A, Corneli PS, Olivera BM. Evolution of Conus peptide toxins: analysis of Conus californicus Reeve, 1844. Molecular Phylogenetics and Evolution. 56: 1-12. PMID 20363338 DOI: 10.1016/J.Ympev.2010.03.029  0.303
2010 Chen P, Dendorfer A, Finol-Urdaneta RK, Terlau H, Olivera BM. Biochemical characterization of kappaM-RIIIJ, a Kv1.2 channel blocker: evaluation of cardioprotective effects of kappaM-conotoxins. The Journal of Biological Chemistry. 285: 14882-9. PMID 20220134 DOI: 10.1074/jbc.M109.068486  0.363
2010 Gowd KH, Yarotskyy V, Elmslie KS, Skalicky JJ, Olivera BM, Bulaj G. Site-specific effects of diselenide bridges on the oxidative folding of a cystine knot peptide, omega-selenoconotoxin GVIA. Biochemistry. 49: 2741-52. PMID 20175537 DOI: 10.1021/Bi902137C  0.408
2010 Safavi-Hemami H, Bulaj G, Olivera BM, Williamson NA, Purcell AW. Identification of Conus peptidylprolyl cis-trans isomerases (PPIases) and assessment of their role in the oxidative folding of conotoxins. The Journal of Biological Chemistry. 285: 12735-46. PMID 20147296 DOI: 10.1074/Jbc.M109.078691  0.363
2010 Seronay RA, Fedosov AE, Astilla MA, Watkins M, Saguil N, Heralde FM, Tagaro S, Poppe GT, Aliño PM, Oliverio M, Kantor YI, Concepcion GP, Olivera BM. Accessing novel conoidean venoms: Biodiverse lumun-lumun marine communities, an untapped biological and toxinological resource. Toxicon : Official Journal of the International Society On Toxinology. 56: 1257-66. PMID 20005243 DOI: 10.1016/j.toxicon.2009.12.002  0.342
2009 Peraud O, Biggs JS, Hughen RW, Light AR, Concepcion GP, Olivera BM, Schmidt EW. Microhabitats within venomous cone snails contain diverse actinobacteria. Applied and Environmental Microbiology. 75: 6820-6. PMID 19749071 DOI: 10.1128/Aem.01238-09  0.314
2009 Walker CS, Jensen S, Ellison M, Matta JA, Lee WY, Imperial JS, Duclos N, Brockie PJ, Madsen DM, Isaac JT, Olivera B, Maricq AV. A novel Conus snail polypeptide causes excitotoxicity by blocking desensitization of AMPA receptors. Current Biology : Cb. 19: 900-8. PMID 19481459 DOI: 10.1016/J.Cub.2009.05.017  0.387
2009 Twede VD, Miljanich G, Olivera BM, Bulaj G. Neuroprotective and cardioprotective conopeptides: an emerging class of drug leads. Current Opinion in Drug Discovery & Development. 12: 231-9. PMID 19333868  0.809
2009 Twede VD, Teichert RW, Walker CS, Gruszczy?ski P, Ka?mierkiewicz R, Bulaj G, Olivera BM. Conantokin-Br from Conus brettinghami and selectivity determinants for the NR2D subunit of the NMDA receptor. Biochemistry. 48: 4063-73. PMID 19309162 DOI: 10.1021/Bi802259A  0.799
2009 Zhang MM, McArthur JR, Azam L, Bulaj G, Olivera BM, French RJ, Yoshikami D. Synergistic and antagonistic interactions between tetrodotoxin and mu-conotoxin in blocking voltage-gated sodium channels. Channels (Austin, Tex.). 3: 32-8. PMID 19221510 DOI: 10.4161/Chan.3.1.7500  0.414
2009 Khoo KK, Feng ZP, Smith BJ, Zhang MM, Yoshikami D, Olivera BM, Bulaj G, Norton RS. Structure of the analgesic mu-conotoxin KIIIA and effects on the structure and function of disulfide deletion. Biochemistry. 48: 1210-9. PMID 19170536 DOI: 10.1021/Bi801998A  0.332
2009 Han TS, Zhang MM, Walewska A, Gruszczynski P, Robertson CR, Cheatham TE, Yoshikami D, Olivera BM, Bulaj G. Structurally minimized mu-conotoxin analogues as sodium channel blockers: implications for designing conopeptide-based therapeutics. Chemmedchem. 4: 406-14. PMID 19107760 DOI: 10.1002/Cmdc.200800292  0.376
2009 Holford M, Zhang MM, Gowd KH, Azam L, Green BR, Watkins M, Ownby JP, Yoshikami D, Bulaj G, Olivera BM. Pruning nature: Biodiversity-derived discovery of novel sodium channel blocking conotoxins from Conus bullatus. Toxicon : Official Journal of the International Society On Toxinology. 53: 90-8. PMID 18950653 DOI: 10.1016/J.Toxicon.2008.10.017  0.389
2009 Aguilar MB, de la Rosa RA, Falcón A, Olivera BM, Heimer de la Cotera EP. Peptide pal9a from the venom of the turrid snail Polystira albida from the Gulf of Mexico: purification, characterization, and comparison with P-conotoxin-like (framework IX) conoidean peptides. Peptides. 30: 467-76. PMID 18948154 DOI: 10.1016/j.peptides.2008.09.016  0.356
2009 McArthur JR, Zhang M, Azam L, Luo S, Olivera BM, Yoshikami D, Bulaj G, Levinson SR, French RJ. Molecular Determinants of μ-Conotoxin KIIIA Block of Voltage-Gated Sodium Channels Biophysical Journal. 96: 248a. DOI: 10.1016/J.Bpj.2008.12.1219  0.339
2009 Teichert RW, Jimenez EC, Olivera BM. Biology and Pharmacology of Conotoxins Botulinum Toxin: Therapeutic Clinical Practice and Science. 446-464. DOI: 10.1016/B978-1-4160-4928-9.00036-6  0.666
2008 Olivera BM, Quik M, Vincler M, McIntosh JM. Subtype-selective conopeptides targeted to nicotinic receptors: Concerted discovery and biomedical applications. Channels (Austin, Tex.). 2: 143-52. PMID 18849660 DOI: 10.4161/chan.2.2.6276  0.367
2008 Walewska A, Skalicky JJ, Davis DR, Zhang MM, Lopez-Vera E, Watkins M, Han TS, Yoshikami D, Olivera BM, Bulaj G. NMR-based mapping of disulfide bridges in cysteine-rich peptides: application to the mu-conotoxin SxIIIA. Journal of the American Chemical Society. 130: 14280-6. PMID 18831583 DOI: 10.1021/Ja804303P  0.358
2008 Yao S, Zhang MM, Yoshikami D, Azam L, Olivera BM, Bulaj G, Norton RS. Structure, dynamics, and selectivity of the sodium channel blocker mu-conotoxin SIIIA. Biochemistry. 47: 10940-9. PMID 18798648 DOI: 10.1021/Bi801010U  0.372
2008 Han TS, Teichert RW, Olivera BM, Bulaj G. Conus venoms - a rich source of peptide-based therapeutics. Current Pharmaceutical Design. 14: 2462-79. PMID 18781995 DOI: 10.2174/138161208785777469  0.715
2008 Gowd KH, Twede V, Watkins M, Krishnan KS, Teichert RW, Bulaj G, Olivera BM. Conantokin-P, an unusual conantokin with a long disulfide loop. Toxicon : Official Journal of the International Society On Toxinology. 52: 203-13. PMID 18586049 DOI: 10.1016/J.Toxicon.2008.04.178  0.801
2008 Chen P, Garrett JE, Watkins M, Olivera BM. Purification and characterization of a novel excitatory peptide from Conus distans venom that defines a novel gene superfamily of conotoxins. Toxicon : Official Journal of the International Society On Toxinology. 52: 139-45. PMID 18586046 DOI: 10.1016/j.toxicon.2008.05.014  0.392
2008 Teichert RW, Garcia CC, Potian JG, Schmidt JJ, Witzemann V, Olivera BM, McArdle JJ. Peptide-toxin tools for probing the expression and function of fetal and adult subtypes of the nicotinic acetylcholine receptor. Annals of the New York Academy of Sciences. 1132: 61-70. PMID 18567854 DOI: 10.1196/Annals.1405.015  0.726
2008 Imperial JS, Chen P, Sporning A, Terlau H, Daly NL, Craik DJ, Alewood PF, Olivera BM. Tyrosine-rich conopeptides affect voltage-gated K+ channels. The Journal of Biological Chemistry. 283: 23026-32. PMID 18505731 DOI: 10.1074/Jbc.M800084200  0.303
2008 Fiedler B, Zhang MM, Buczek O, Azam L, Bulaj G, Norton RS, Olivera BM, Yoshikami D. Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7. Biochemical Pharmacology. 75: 2334-44. PMID 18486102 DOI: 10.1016/J.Bcp.2008.03.019  0.342
2008 Liu Y, Padgett D, Takahashi M, Li H, Sayeed A, Teichert RW, Olivera BM, McArdle JJ, Green WN, Lin W. Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning. Development (Cambridge, England). 135: 1957-67. PMID 18434415 DOI: 10.1242/Dev.018119  0.672
2008 Oppenheim RW, Calderó J, Cuitat D, Esquerda J, McArdle JJ, Olivera BM, Prevette D, Teichert RW. The rescue of developing avian motoneurons from programmed cell death by a selective inhibitor of the fetal muscle-specific nicotinic acetylcholine receptor. Developmental Neurobiology. 68: 972-80. PMID 18418876 DOI: 10.1002/Dneu.20636  0.709
2008 Ellison M, Feng ZP, Park AJ, Zhang X, Olivera BM, McIntosh JM, Norton RS. Alpha-RgIA, a novel conotoxin that blocks the alpha9alpha10 nAChR: structure and identification of key receptor-binding residues. Journal of Molecular Biology. 377: 1216-27. PMID 18295795 DOI: 10.1016/j.jmb.2008.01.082  0.332
2008 Zugasti-Cruz A, Aguilar MB, Falcón A, Olivera BM, Heimer de la Cotera EP. Two new 4-Cys conotoxins (framework 14) of the vermivorous snail Conus austini from the Gulf of Mexico with activity in the central nervous system of mice. Peptides. 29: 179-85. PMID 18206266 DOI: 10.1016/j.peptides.2007.09.021  0.363
2008 Aguilar MB, Luna-Ramírez KS, Echeverría D, Falcón A, Olivera BM, Heimer de la Cotera EP, Maillo M. Conorfamide-Sr2, a gamma-carboxyglutamate-containing FMRFamide-related peptide from the venom of Conus spurius with activity in mice and mollusks. Peptides. 29: 186-95. PMID 18201803 DOI: 10.1016/j.peptides.2007.09.022  0.417
2008 Lopez-Vera E, Walewska A, Skalicky JJ, Olivera BM, Bulaj G. Role of hydroxyprolines in the in vitro oxidative folding and biological activity of conotoxins. Biochemistry. 47: 1741-51. PMID 18189422 DOI: 10.1021/Bi701934M  0.372
2008 Lluisma AO, López-Vera E, Bulaj G, Watkins M, Olivera BM. Characterization of a novel psi-conotoxin from Conus parius Reeve. Toxicon : Official Journal of the International Society On Toxinology. 51: 174-80. PMID 18054976 DOI: 10.1016/J.Toxicon.2007.07.009  0.439
2008 Bulaj G, Olivera BM. Folding of conotoxins: formation of the native disulfide bridges during chemical synthesis and biosynthesis of Conus peptides. Antioxidants & Redox Signaling. 10: 141-55. PMID 17961068 DOI: 10.1089/Ars.2007.1856  0.358
2007 Ellison M, Olivera BM. Alpha4/3 conotoxins: phylogenetic distribution, functional properties, and structure-function insights. Chemical Record (New York, N.Y.). 7: 341-53. PMID 18050267 DOI: 10.1002/tcr.20131  0.334
2007 Teichert RW, Jimenez EC, Twede V, Watkins M, Hollmann M, Bulaj G, Olivera BM. Novel conantokins from Conus parius venom are specific antagonists of N-methyl-D-aspartate receptors. The Journal of Biological Chemistry. 282: 36905-13. PMID 17962189 DOI: 10.1074/Jbc.M706611200  0.806
2007 Olivera BM, Teichert RW. Diversity of the neurotoxic Conus peptides: a model for concerted pharmacological discovery. Molecular Interventions. 7: 251-60. PMID 17932414 DOI: 10.1124/Mi.7.5.7  0.725
2007 Biggs JS, Rosenfeld Y, Shai Y, Olivera BM. Conolysin-Mt: a conus peptide that disrupts cellular membranes. Biochemistry. 46: 12586-93. PMID 17927208 DOI: 10.1021/Bi700775P  0.362
2007 Imperial JS, Kantor Y, Watkins M, Heralde FM, Stevenson B, Chen P, Hansson K, Stenflo J, Ownby JP, Bouchet P, Olivera BM. Venomous auger snail Hastula (Impages) hectica (Linnaeus, 1758): molecular phylogeny, foregut anatomy and comparative toxinology. Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution. 308: 744-56. PMID 17886885 DOI: 10.1002/Jez.B.21195  0.39
2007 Zhang MM, Green BR, Catlin P, Fiedler B, Azam L, Chadwick A, Terlau H, McArthur JR, French RJ, Gulyas J, Rivier JE, Smith BJ, Norton RS, Olivera BM, Yoshikami D, et al. Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels. The Journal of Biological Chemistry. 282: 30699-706. PMID 17724025 DOI: 10.1074/Jbc.M704616200  0.331
2007 Buczek O, Wei D, Babon JJ, Yang X, Fiedler B, Chen P, Yoshikami D, Olivera BM, Bulaj G, Norton RS. Structure and sodium channel activity of an excitatory I1-superfamily conotoxin. Biochemistry. 46: 9929-40. PMID 17696362 DOI: 10.1021/Bi701925D  0.362
2007 Jimenez EC, Olivera BM, Teichert RW. AlphaC-conotoxin PrXA: a new family of nicotinic acetylcholine receptor antagonists. Biochemistry. 46: 8717-24. PMID 17608455 DOI: 10.1021/Bi700582M  0.752
2007 Whiteaker P, Christensen S, Yoshikami D, Dowell C, Watkins M, Gulyas J, Rivier J, Olivera BM, McIntosh JM. Discovery, synthesis, and structure activity of a highly selective alpha7 nicotinic acetylcholine receptor antagonist. Biochemistry. 46: 6628-38. PMID 17497892 DOI: 10.1021/Bi7004202  0.347
2007 Green BR, Catlin P, Zhang MM, Fiedler B, Bayudan W, Morrison A, Norton RS, Smith BJ, Yoshikami D, Olivera BM, Bulaj G. Conotoxins containing nonnatural backbone spacers: cladistic-based design, chemical synthesis, and improved analgesic activity. Chemistry & Biology. 14: 399-407. PMID 17462575 DOI: 10.1016/J.Chembiol.2007.02.009  0.367
2007 López-Vera E, Jacobsen RB, Ellison M, Olivera BM, Teichert RW. A novel alpha conotoxin (alpha-PIB) isolated from C. purpurascens is selective for skeletal muscle nicotinic acetylcholine receptors. Toxicon : Official Journal of the International Society On Toxinology. 49: 1193-9. PMID 17382984 DOI: 10.1016/J.Toxicon.2007.02.007  0.71
2007 Aguilar MB, López-Vera E, Heimer de la Cotera EP, Falcón A, Olivera BM, Maillo M. I-conotoxins in vermivorous species of the West Atlantic: peptide sr11a from Conus spurius. Peptides. 28: 18-23. PMID 17166627 DOI: 10.1016/j.peptides.2006.08.024  0.386
2007 Luna-Ramírez KS, Aguilar MB, Falcón A, Heimer de la Cotera EP, Olivera BM, Maillo M. An O-conotoxin from the vermivorous Conus spurius active on mice and mollusks. Peptides. 28: 24-30. PMID 17166626 DOI: 10.1016/j.peptides.2006.08.025  0.395
2007 Teichert RW, Jacobsen R, Terlau H, Yoshikami D, Olivera BM. Discovery and characterization of the short kappaA-conotoxins: a novel subfamily of excitatory conotoxins. Toxicon : Official Journal of the International Society On Toxinology. 49: 318-28. PMID 17118419 DOI: 10.1016/J.Toxicon.2006.10.001  0.725
2006 Vincler M, Wittenauer S, Parker R, Ellison M, Olivera BM, McIntosh JM. Molecular mechanism for analgesia involving specific antagonism of alpha9alpha10 nicotinic acetylcholine receptors. Proceedings of the National Academy of Sciences of the United States of America. 103: 17880-4. PMID 17101979 DOI: 10.1073/pnas.0608715103  0.312
2006 Chi SW, Kim DH, Olivera BM, McIntosh JM, Han KH. NMR structure determination of alpha-conotoxin BuIA, a novel neuronal nicotinic acetylcholine receptor antagonist with an unusual 4/4 disulfide scaffold. Biochemical and Biophysical Research Communications. 349: 1228-34. PMID 16979596 DOI: 10.1016/j.bbrc.2006.08.164  0.322
2006 Wang X, Engisch KL, Teichert RW, Olivera BM, Pinter MJ, Rich MM. Prolongation of evoked and spontaneous synaptic currents at the neuromuscular junction after activity blockade is caused by the upregulation of fetal acetylcholine receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8983-7. PMID 16943554 DOI: 10.1523/Jneurosci.2493-06.2006  0.693
2006 Imperial JS, Bansal PS, Alewood PF, Daly NL, Craik DJ, Sporning A, Terlau H, López-Vera E, Bandyopadhyay PK, Olivera BM. A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins. Biochemistry. 45: 8331-40. PMID 16819832 DOI: 10.1021/Bi060263R  0.45
2006 Talley TT, Olivera BM, Han KH, Christensen SB, Dowell C, Tsigelny I, Ho KY, Taylor P, McIntosh JM. Alpha-conotoxin OmIA is a potent ligand for the acetylcholine-binding protein as well as alpha3beta2 and alpha7 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 281: 24678-86. PMID 16803900 DOI: 10.1074/Jbc.M602969200  0.378
2006 Bulaj G, Zhang MM, Green BR, Fiedler B, Layer RT, Wei S, Nielsen JS, Low SJ, Klein BD, Wagstaff JD, Chicoine L, Harty TP, Terlau H, Yoshikami D, Olivera BM. Synthetic muO-conotoxin MrVIB blocks TTX-resistant sodium channel NaV1.8 and has a long-lasting analgesic activity. Biochemistry. 45: 7404-14. PMID 16752929 DOI: 10.1021/Bi060159+  0.374
2006 Chi SW, Kim DH, Olivera BM, McIntosh JM, Han KH. Solution conformation of a neuronal nicotinic acetylcholine receptor antagonist alpha-conotoxin OmIA that discriminates alpha3 vs. alpha6 nAChR subtypes. Biochemical and Biophysical Research Communications. 345: 248-54. PMID 16678128 DOI: 10.1016/j.bbrc.2006.04.099  0.319
2006 Bayrhuber M, Graf R, Ferber M, Zweckstetter M, Imperial J, Garrett JE, Olivera BM, Terlau H, Becker S. Production of recombinant Conkunitzin-S1 in Escherichia coli. Protein Expression and Purification. 47: 640-4. PMID 16542850 DOI: 10.1016/j.pep.2006.01.019  0.344
2006 Zhang MM, Fiedler B, Green BR, Catlin P, Watkins M, Garrett JE, Smith BJ, Yoshikami D, Olivera BM, Bulaj G. Structural and functional diversities among mu-conotoxins targeting TTX-resistant sodium channels. Biochemistry. 45: 3723-32. PMID 16533055 DOI: 10.1021/Bi052162J  0.39
2006 Zorn S, Leipold E, Hansel A, Bulaj G, Olivera BM, Terlau H, Heinemann SH. The muO-conotoxin MrVIA inhibits voltage-gated sodium channels by associating with domain-3. Febs Letters. 580: 1360-4. PMID 16458302 DOI: 10.1016/J.Febslet.2006.01.057  0.326
2006 Ellison M, Haberlandt C, Gomez-Casati ME, Watkins M, Elgoyhen AB, McIntosh JM, Olivera BM. Alpha-RgIA: a novel conotoxin that specifically and potently blocks the alpha9alpha10 nAChR. Biochemistry. 45: 1511-7. PMID 16445293 DOI: 10.1021/bi0520129  0.333
2006 Teichert RW, López-Vera E, Gulyas J, Watkins M, Rivier J, Olivera BM. Definition and characterization of the short alphaA-conotoxins: a single residue determines dissociation kinetics from the fetal muscle nicotinic acetylcholine receptor. Biochemistry. 45: 1304-12. PMID 16430227 DOI: 10.1021/Bi052016D  0.738
2006 Zugasti-Cruz A, Maillo M, López-Vera E, Falcón A, Heimer de la Cotera EP, Olivera BM, Aguilar MB. Amino acid sequence and biological activity of a gamma-conotoxin-like peptide from the worm-hunting snail Conus austini. Peptides. 27: 506-11. PMID 16325964 DOI: 10.1016/j.peptides.2005.07.021  0.39
2005 Buczek O, Bulaj G, Olivera BM. Conotoxins and the posttranslational modification of secreted gene products. Cellular and Molecular Life Sciences : Cmls. 62: 3067-79. PMID 16314929 DOI: 10.1007/S00018-005-5283-0  0.393
2005 Chi SW, Lee SH, Kim DH, Kim JS, Olivera BM, McIntosh JM, Han KH. Solution structure of alpha-conotoxin PIA, a novel antagonist of alpha6 subunit containing nicotinic acetylcholine receptors. Biochemical and Biophysical Research Communications. 338: 1990-7. PMID 16289101 DOI: 10.1016/j.bbrc.2005.10.176  0.328
2005 Aguilar MB, López-Vera E, Ortiz E, Becerril B, Possani LD, Olivera BM, Heimer de la Cotera EP. A novel conotoxin from Conus delessertii with posttranslationally modified lysine residues. Biochemistry. 44: 11130-6. PMID 16101297 DOI: 10.1021/bi050518l  0.313
2005 Buczek O, Yoshikami D, Watkins M, Bulaj G, Jimenez EC, Olivera BM. Characterization of D-amino-acid-containing excitatory conotoxins and redefinition of the I-conotoxin superfamily. The Febs Journal. 272: 4178-88. PMID 16098199 DOI: 10.1111/J.1742-4658.2005.04830.X  0.318
2005 Corpuz GP, Jacobsen RB, Jimenez EC, Watkins M, Walker C, Colledge C, Garrett JE, McDougal O, Li W, Gray WR, Hillyard DR, Rivier J, McIntosh JM, Cruz LJ, Olivera BM. Definition of the M-conotoxin superfamily: characterization of novel peptides from molluscivorous Conus venoms. Biochemistry. 44: 8176-86. PMID 15924437 DOI: 10.1021/Bi047541B  0.395
2005 Teichert RW, Jimenez EC, Olivera BM. Alpha S-conotoxin RVIIIA: a structurally unique conotoxin that broadly targets nicotinic acetylcholine receptors. Biochemistry. 44: 7897-902. PMID 15910004 DOI: 10.1021/Bi047274+  0.733
2005 Bulaj G, West PJ, Garrett JE, Watkins M, Marsh M, Zhang MM, Norton RS, Smith BJ, Yoshikami D, Olivera BM. Novel conotoxins from Conus striatus and Conus kinoshitai selectively block TTX-resistant sodium channels. Biochemistry. 44: 7259-65. PMID 15882064 DOI: 10.1021/BI0473408  0.439
2005 Bayrhuber M, Vijayan V, Ferber M, Graf R, Korukottu J, Imperial J, Garrett JE, Olivera BM, Terlau H, Zweckstetter M, Becker S. Conkunitzin-S1 is the first member of a new Kunitz-type neurotoxin family. Structural and functional characterization. The Journal of Biological Chemistry. 280: 23766-70. PMID 15833744 DOI: 10.1074/jbc.C500064200  0.314
2005 Fuller E, Green BR, Catlin P, Buczek O, Nielsen JS, Olivera BM, Bulaj G. Oxidative folding of conotoxins sharing an identical disulfide bridging framework. The Febs Journal. 272: 1727-38. PMID 15794759 DOI: 10.1111/J.1742-4658.2005.04602.X  0.311
2005 Garrett JE, Buczek O, Watkins M, Olivera BM, Bulaj G. Biochemical and gene expression analyses of conotoxins in Conus textile venom ducts. Biochemical and Biophysical Research Communications. 328: 362-7. PMID 15670792 DOI: 10.1016/J.Bbrc.2004.12.178  0.311
2005 Teichert RW, Rivier J, Torres J, Dykert J, Miller C, Olivera BM. A uniquely selective inhibitor of the mammalian fetal neuromuscular nicotinic acetylcholine receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 732-6. PMID 15659611 DOI: 10.1523/Jneurosci.4065-04.2005  0.737
2005 Aguilar MB, López-Vera E, Imperial JS, Falcón A, Olivera BM, de la Cotera EP. Putative gamma-conotoxins in vermivorous cone snails: the case of Conus delessertii. Peptides. 26: 23-7. PMID 15626501 DOI: 10.1016/j.peptides.2004.10.012  0.391
2005 Vianna Braga MC, Konno K, Portaro FC, de Freitas JC, Yamane T, Olivera BM, Pimenta DC. Mass spectrometric and high performance liquid chromatography profiling of the venom of the Brazilian vermivorous mollusk Conus regius: feeding behavior and identification of one novel conotoxin. Toxicon : Official Journal of the International Society On Toxinology. 45: 113-22. PMID 15581690 DOI: 10.1016/j.toxicon.2004.09.018  0.462
2005 Buczek O, Yoshikami D, Bulaj G, Jimenez EC, Olivera BM. Post-translational amino acid isomerization: a functionally important D-amino acid in an excitatory peptide. The Journal of Biological Chemistry. 280: 4247-53. PMID 15561705 DOI: 10.1074/Jbc.M405835200  0.341
2005 Azam L, Dowell C, Watkins M, Stitzel JA, Olivera BM, McIntosh JM. Alpha-conotoxin BuIA, a novel peptide from Conus bullatus, distinguishes among neuronal nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 280: 80-7. PMID 15520009 DOI: 10.1074/Jbc.M406281200  0.329
2004 Ellison M, Gao F, Wang HL, Sine SM, McIntosh JM, Olivera BM. Alpha-conotoxins ImI and ImII target distinct regions of the human alpha7 nicotinic acetylcholine receptor and distinguish human nicotinic receptor subtypes. Biochemistry. 43: 16019-26. PMID 15609996 DOI: 10.1021/Bi048918G  0.332
2004 Kang J, Low W, Norberg T, Meisenhelder J, Hansson K, Stenflo J, Zhou GP, Imperial J, Olivera BM, Rigby AC, Craig AG. Total chemical synthesis and NMR characterization of the glycopeptide tx5a, a heavily post-translationally modified conotoxin, reveals that the glycan structure is alpha-D-Gal-(1-->3)-alpha-D-GalNAc. European Journal of Biochemistry / Febs. 271: 4939-49. PMID 15606782 DOI: 10.1111/J.1432-1033.2004.04464.X  0.343
2004 Teichert RW, Rivier J, Dykert J, Cervini L, Gulyas J, Bulaj G, Ellison M, Olivera BM. AlphaA-Conotoxin OIVA defines a new alphaA-conotoxin subfamily of nicotinic acetylcholine receptor inhibitors. Toxicon : Official Journal of the International Society On Toxinology. 44: 207-14. PMID 15246771 DOI: 10.1016/J.Toxicon.2004.05.026  0.75
2004 López-Vera E, Heimer de la Cotera EP, Maillo M, Riesgo-Escovar JR, Olivera BM, Aguilar MB. A novel structural class of toxins: the methionine-rich peptides from the venoms of turrid marine snails (Mollusca, Conoidea). Toxicon : Official Journal of the International Society On Toxinology. 43: 365-74. PMID 15051399 DOI: 10.1016/j.toxicon.2003.12.008  0.397
2004 Chi SW, Kim DH, Olivera BM, McIntosh JM, Han KH. Solution conformation of alpha-conotoxin GIC, a novel potent antagonist of alpha3beta2 nicotinic acetylcholine receptors. The Biochemical Journal. 380: 347-52. PMID 14992691 DOI: 10.1042/BJ20031792  0.357
2004 Buczek O, Olivera BM, Bulaj G. Propeptide does not act as an intramolecular chaperone but facilitates protein disulfide isomerase-assisted folding of a conotoxin precursor. Biochemistry. 43: 1093-101. PMID 14744155 DOI: 10.1021/Bi0354233  0.329
2004 Santos AD, McIntosh JM, Hillyard DR, Cruz LJ, Olivera BM. The A-superfamily of conotoxins: structural and functional divergence. The Journal of Biological Chemistry. 279: 17596-606. PMID 14701840 DOI: 10.1074/jbc.M309654200  0.424
2003 Bulaj G, Buczek O, Goodsell I, Jimenez EC, Kranski J, Nielsen JS, Garrett JE, Olivera BM. Efficient oxidative folding of conotoxins and the radiation of venomous cone snails. Proceedings of the National Academy of Sciences of the United States of America. 100: 14562-8. PMID 14573706 DOI: 10.1073/Pnas.2335845100  0.377
2003 Imperial JS, Watkins M, Chen P, Hillyard DR, Cruz LJ, Olivera BM. The augertoxins: biochemical characterization of venom components from the toxoglossate gastropod Terebra subulata. Toxicon : Official Journal of the International Society On Toxinology. 42: 391-8. PMID 14505939 DOI: 10.1016/S0041-0101(03)00169-7  0.36
2003 Keizer DW, West PJ, Lee EF, Yoshikami D, Olivera BM, Bulaj G, Norton RS. Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA. The Journal of Biological Chemistry. 278: 46805-13. PMID 12970353 DOI: 10.1074/Jbc.M309222200  0.39
2003 Chi SW, Park KH, Suk JE, Olivera BM, McIntosh JM, Han KH. Solution conformation of alphaA-conotoxin EIVA, a potent neuromuscular nicotinic acetylcholine receptor antagonist from Conus ermineus. The Journal of Biological Chemistry. 278: 42208-13. PMID 12900418 DOI: 10.1074/jbc.M303342200  0.353
2003 Van Wagoner RM, Jacobsen RB, Olivera BM, Ireland CM. Characterization and three-dimensional structure determination of psi-conotoxin Piiif, a novel noncompetitive antagonist of nicotinic acetylcholine receptors. Biochemistry. 42: 6353-62. PMID 12767216 DOI: 10.1021/Bi0272757  0.392
2002 West PJ, Bulaj G, Garrett JE, Olivera BM, Yoshikami D. Mu-conotoxin SmIIIA, a potent inhibitor of tetrodotoxin-resistant sodium channels in amphibian sympathetic and sensory neurons. Biochemistry. 41: 15388-93. PMID 12484778 DOI: 10.1021/Bi0265628  0.413
2002 Jimenez EC, Donevan S, Walker C, Zhou LM, Nielsen J, Cruz LJ, Armstrong H, White HS, Olivera BM. Conantokin-L, a new NMDA receptor antagonist: determinants for anticonvulsant potency. Epilepsy Research. 51: 73-80. PMID 12350383 DOI: 10.1016/S0920-1211(02)00101-8  0.364
2002 Miles LA, Dy CY, Nielsen J, Barnham KJ, Hinds MG, Olivera BM, Bulaj G, Norton RS. Structure of a novel P-superfamily spasmodic conotoxin reveals an inhibitory cystine knot motif. The Journal of Biological Chemistry. 277: 43033-40. PMID 12193600 DOI: 10.1074/Jbc.M206690200  0.363
2002 McIntosh JM, Dowell C, Watkins M, Garrett JE, Yoshikami D, Olivera BM. Alpha-conotoxin GIC from Conus geographus, a novel peptide antagonist of nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 277: 33610-5. PMID 12114524 DOI: 10.1074/jbc.M205102200  0.423
2002 Maillo M, Aguilar MB, Lopéz-Vera E, Craig AG, Bulaj G, Olivera BM, Heimer de la Cotera EP. Conorfamide, a Conus venom peptide belonging to the RFamide family of neuropeptides. Toxicon : Official Journal of the International Society On Toxinology. 40: 401-7. PMID 11738233 DOI: 10.1016/S0041-0101(01)00176-3  0.382
2001 Bulaj G, DeLaCruz R, Azimi-Zonooz A, West P, Watkins M, Yoshikami D, Olivera BM. Delta-conotoxin structure/function through a cladistic analysis. Biochemistry. 40: 13201-8. PMID 11683628 DOI: 10.1021/Bi010683A  0.384
2001 Espiritu DJ, Watkins M, Dia-Monje V, Cartier GE, Cruz LJ, Olivera BM. Venomous cone snails: molecular phylogeny and the generation of toxin diversity. Toxicon : Official Journal of the International Society On Toxinology. 39: 1899-916. PMID 11600154 DOI: 10.1016/S0041-0101(01)00175-1  0.689
2001 Kulak JM, McIntosh JM, Yoshikami D, Olivera BM. Nicotine-evoked transmitter release from synaptosomes: functional association of specific presynaptic acetylcholine receptors and voltage-gated calcium channels. Journal of Neurochemistry. 77: 1581-9. PMID 11413241 DOI: 10.1046/J.1471-4159.2001.00357.X  0.775
2001 Jones RM, Cartier GE, McIntosh JM, Bulaj G, Farrar VE, Olivera BM. Composition and therapeutic utility of conotoxins from genus Conus. Patent status 1996 - 2000 Expert Opinion On Therapeutic Patents. 11: 603-623. DOI: 10.1517/13543776.11.4.603  0.694
2000 McIntosh JM, Corpuz GO, Layer RT, Garrett JE, Wagstaff JD, Bulaj G, Vyazovkina A, Yoshikami D, Cruz LJ, Olivera BM. Isolation and characterization of a novel conus peptide with apparent antinociceptive activity. The Journal of Biological Chemistry. 275: 32391-7. PMID 10900201 DOI: 10.1074/Jbc.M003619200  0.389
2000 Jacobsen RB, Koch ED, Lange-Malecki B, Stocker M, Verhey J, Van Wagoner RM, Vyazovkina A, Olivera BM, Terlau H. Single amino acid substitutions in kappa-conotoxin PVIIA disrupt interaction with the shaker K+ channel. The Journal of Biological Chemistry. 275: 24639-44. PMID 10818087 DOI: 10.1074/jbc.C900990199  0.353
2000 Safo P, Rosenbaum T, Shcherbatko A, Choi DY, Han E, Toledo-Aral JJ, Olivera BM, Brehm P, Mandel G. Distinction among neuronal subtypes of voltage-activated sodium channels by mu-conotoxin PIIIA. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 76-80. PMID 10627583 DOI: 10.1523/Jneurosci.20-01-00076.2000  0.344
2000 White HS, McCabe RT, Armstrong H, Donevan SD, Cruz LJ, Abogadie FC, Torres J, Rivier JE, Paarmann I, Hollmann M, Olivera BM. In vitro and in vivo characterization of conantokin-R, a selective NMDA receptor antagonist isolated from the venom of the fish-hunting snail Conus radiatus. The Journal of Pharmacology and Experimental Therapeutics. 292: 425-32. PMID 10604979  0.415
1999 McIntosh JM, Santos AD, Olivera BM. Conus peptides targeted to specific nicotinic acetylcholine receptor subtypes. Annual Review of Biochemistry. 68: 59-88. PMID 10872444 DOI: 10.1146/annurev.biochem.68.1.59  0.342
1999 Luo S, Nguyen TA, Cartier GE, Olivera BM, Yoshikami D, McIntosh JM. Single-residue alteration in alpha-conotoxin PnIA switches its nAChR subtype selectivity. Biochemistry. 38: 14542-8. PMID 10545176 DOI: 10.1021/bi991252j  0.723
1999 Jacobsen RB, DelaCruz RG, Grose JH, McIntosh JM, Yoshikami D, Olivera BM. Critical residues influence the affinity and selectivity of alpha-conotoxin MI for nicotinic acetylcholine receptors. Biochemistry. 38: 13310-5. PMID 10529206 DOI: 10.1021/Bi9907476  0.32
1999 Walker CS, Steel D, Jacobsen RB, Lirazan MB, Cruz LJ, Hooper D, Shetty R, DelaCruz RC, Nielsen JS, Zhou LM, Bandyopadhyay P, Craig AG, Olivera BM. The T-superfamily of conotoxins. The Journal of Biological Chemistry. 274: 30664-71. PMID 10521453 DOI: 10.1074/Jbc.274.43.30664  0.375
1999 Olivera BM, Walker C, Cartier GE, Hooper D, Santos AD, Schoenfeld R, Shetty R, Watkins M, Bandyopadhyay P, Hillyard DR. Speciation of cone snails and interspecific hyperdivergence of their venom peptides. Potential evolutionary significance of introns. Annals of the New York Academy of Sciences. 870: 223-37. PMID 10415486 DOI: 10.1111/j.1749-6632.1999.tb08883.x  0.72
1999 McIntosh JM, Olivera BM, Cruz LJ. Conus peptides as probes for ion channels. Methods in Enzymology. 294: 605-24. PMID 9916250 DOI: 10.1016/S0076-6879(99)94034-X  0.405
1998 López MG, Montiel C, Herrero CJ, García-Palomero E, Mayorgas I, Hernández-Guijo JM, Villarroya M, Olivares R, Gandía L, McIntosh JM, Olivera BM, García AG. Unmasking the functions of the chromaffin cell alpha7 nicotinic receptor by using short pulses of acetylcholine and selective blockers. Proceedings of the National Academy of Sciences of the United States of America. 95: 14184-9. PMID 9826675 DOI: 10.1073/Pnas.95.24.14184  0.315
1998 Luo S, Kulak JM, Cartier GE, Jacobsen RB, Yoshikami D, Olivera BM, McIntosh JM. alpha-conotoxin AuIB selectively blocks alpha3 beta4 nicotinic acetylcholine receptors and nicotine-evoked norepinephrine release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 8571-9. PMID 9786965  0.778
1998 England LJ, Imperial J, Jacobsen R, Craig AG, Gulyas J, Akhtar M, Rivier J, Julius D, Olivera BM. Inactivation of a serotonin-gated ion channel by a polypeptide toxin from marine snails. Science (New York, N.Y.). 281: 575-8. PMID 9677203 DOI: 10.1126/science.281.5376.575  0.393
1998 Bandyopadhyay PK, Colledge CJ, Walker CS, Zhou LM, Hillyard DR, Olivera BM. Conantokin-G precursor and its role in gamma-carboxylation by a vitamin K-dependent carboxylase from a Conus snail. The Journal of Biological Chemistry. 273: 5447-50. PMID 9488665 DOI: 10.1074/Jbc.273.10.5447  0.367
1998 Mitchell SS, Shon KJ, Foster MP, Davis DR, Olivera BM, Ireland CM. Three-dimensional solution structure of conotoxin psi-PIIIE, an acetylcholine gated ion channel antagonist. Biochemistry. 37: 1215-20. PMID 9477946 DOI: 10.1021/Bi972186T  0.365
1998 Luo S, Kulak JM, Cartier GE, Jacobsen RB, Yoshikami D, Olivera BM, McIntosh JM. α-Conotoxin AuIB Selectively Blocks α3β4 Nicotinic Acetylcholine Receptors and Nicotine-Evoked Norepinephrine Release The Journal of Neuroscience. 18: 8571-8579. DOI: 10.1523/Jneurosci.18-21-08571.1998  0.771
1997 Kim M, Baro DJ, Lanning CC, Doshi M, Farnham J, Moskowitz HS, Peck JH, Olivera BM, Harris-Warrick RM. Alternative splicing in the pore-forming region of shaker potassium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 8213-24. PMID 9334397 DOI: 10.1523/Jneurosci.17-21-08213.1997  0.333
1997 Jacobsen R, Yoshikami D, Ellison M, Martinez J, Gray WR, Cartier GE, Shon KJ, Groebe DR, Abramson SN, Olivera BM, McIntosh JM. Differential targeting of nicotinic acetylcholine receptors by novel alphaA-conotoxins. The Journal of Biological Chemistry. 272: 22531-7. PMID 9278406 DOI: 10.1074/Jbc.272.36.22531  0.702
1997 Shon KJ, Grilley M, Jacobsen R, Cartier GE, Hopkins C, Gray WR, Watkins M, Hillyard DR, Rivier J, Torres J, Yoshikami D, Olivera BM. A noncompetitive peptide inhibitor of the nicotinic acetylcholine receptor from Conus purpurascens venom. Biochemistry. 36: 9581-7. PMID 9236004 DOI: 10.1021/bi970235w  0.732
1997 Kulak JM, Nguyen TA, Olivera BM, McIntosh JM. Alpha-conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5263-70. PMID 9204910  0.754
1997 Tavazoie SF, Tavazoie MF, McIntosh JM, Olivera BM, Yoshikami D. Differential block of nicotinic synapses on B versus C neurones in sympathetic ganglia of frog by alpha-conotoxins MII and ImI. British Journal of Pharmacology. 120: 995-1000. PMID 9134208 DOI: 10.1038/sj.bjp.0700993  0.348
1997 Craig AG, Jimenez EC, Dykert J, Nielsen DB, Gulyas J, Abogadie FC, Porter J, Rivier JE, Cruz LJ, Olivera BM, McIntosh JM. A novel post-translational modification involving bromination of tryptophan. Identification of the residue, L-6-bromotryptophan, in peptides from Conus imperialis and Conus radiatus venom. The Journal of Biological Chemistry. 272: 4689-98. PMID 9030520 DOI: 10.1074/jbc.272.8.4689  0.376
1997 Kulak JM, Nguyen TA, Olivera BM, McIntosh JM. α-Conotoxin MII Blocks Nicotine-Stimulated Dopamine Release in Rat Striatal Synaptosomes The Journal of Neuroscience. 17: 5263-5270. DOI: 10.1523/Jneurosci.17-14-05263.1997  0.758
1996 Jimenéz EC, Olivera BM, Gray WR, Cruz LJ. Contryphan is a D-tryptophan-containing Conus peptide. The Journal of Biological Chemistry. 271: 28002-5. PMID 8910408 DOI: 10.1074/Jbc.271.45.28002  0.349
1996 Wilson GF, Richardson FC, Fisher TE, Olivera BM, Kaczmarek LK. Identification and characterization of a Ca(2+)-sensitive nonspecific cation channel underlying prolonged repetitive firing in Aplysia neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 3661-71. PMID 8642410 DOI: 10.1523/Jneurosci.16-11-03661.1996  0.35
1996 Cartier GE, Yoshikami D, Gray WR, Luo S, Olivera BM, McIntosh JM. A new alpha-conotoxin which targets alpha3beta2 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 271: 7522-8. PMID 8631783 DOI: 10.1074/Jbc.271.13.7522  0.737
1995 Shon KJ, Grilley MM, Marsh M, Yoshikami D, Hall AR, Kurz B, Gray WR, Imperial JS, Hillyard DR, Olivera BM. Purification, characterization, synthesis, and cloning of the lockjaw peptide from Conus purpurascens venom. Biochemistry. 34: 4913-8. PMID 7711013 DOI: 10.1021/Bi00015A002  0.415
1995 Hopkins C, Grilley M, Miller C, Shon KJ, Cruz LJ, Gray WR, Dykert J, Rivier J, Yoshikami D, Olivera BM. A new family of Conus peptides targeted to the nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 270: 22361-7. PMID 7673220 DOI: 10.1074/Jbc.270.38.22361  0.423
1995 McIntosh JM, Hasson A, Spira ME, Gray WR, Li W, Marsh M, Hillyard DR, Olivera BM. A new family of conotoxins that blocks voltage-gated sodium channels. The Journal of Biological Chemistry. 270: 16796-802. PMID 7622492 DOI: 10.1074/Jbc.270.28.16796  0.369
1994 Filloux F, Schapper A, Naisbitt SR, Olivera BM, McIntosh JM. Complex patterns of [125I]omega-conotoxin GVIA binding site expression during postnatal rat brain development. Brain Research. Developmental Brain Research. 78: 131-6. PMID 8004767 DOI: 10.1016/0165-3806(94)90017-5  0.303
1994 Olivera BM, Miljanich GP, Ramachandran J, Adams ME. Calcium channel diversity and neurotransmitter release: the omega-conotoxins and omega-agatoxins. Annual Review of Biochemistry. 63: 823-67. PMID 7979255 DOI: 10.1146/Annurev.Bi.63.070194.004135  0.335
1994 Adams ME, Olivera BM. Neurotoxins: overview of an emerging research technology. Trends in Neurosciences. 17: 151-5. PMID 7517594 DOI: 10.1016/0166-2236(94)90092-2  0.34
1994 Lev-Ram V, Olivera BM, Levitan IB. A toxin from the venom of the predator snail Conus textile modulates ionic currents in Aplysia bursting pacemaker neuron. Brain Research. 640: 48-55. PMID 7516261 DOI: 10.1016/0006-8993(94)91856-2  0.332
1993 Tisa LS, Olivera BM, Adler J. Inhibition of Escherichia coli chemotaxis by omega-conotoxin, a calcium ion channel blocker. Journal of Bacteriology. 175: 1235-8. PMID 8444785 DOI: 10.1128/Jb.175.5.1235-1238.1993  0.302
1993 Adams ME, Myers RA, Imperial JS, Olivera BM. Toxityping rat brain calcium channels with omega-toxins from spider and cone snail venoms. Biochemistry. 32: 12566-70. PMID 8251474 DOI: 10.1021/Bi00210A003  0.326
1993 McIntosh JM, Foderaro TA, Li W, Ireland CM, Olivera BM. Presence of serotonin in the venom of Conus imperialis. Toxicon : Official Journal of the International Society On Toxinology. 31: 1561-6. PMID 8146869 DOI: 10.1016/0041-0101(93)90340-O  0.398
1993 Monje VD, Haack JA, Naisbitt SR, Miljanich G, Ramachandran J, Nasdasdi L, Olivera BM, Hillyard DR, Gray WR. A new Conus peptide ligand for Ca channel subtypes. Neuropharmacology. 32: 1141-9. PMID 8107968 DOI: 10.1016/0028-3908(93)90008-Q  0.393
1992 McIntosh JM, Adams ME, Olivera BM, Filloux F. Autoradiographic localization of the binding of calcium channel antagonist, [125I]omega-agatoxin IIIA, in rat brain. Brain Research. 594: 109-14. PMID 1467930 DOI: 10.1016/0006-8993(92)91034-C  0.3
1992 Ramilo CA, Zafaralla GC, Nadasdi L, Hammerland LG, Yoshikami D, Gray WR, Kristipati R, Ramachandran J, Miljanich G, Olivera BM. Novel alpha- and omega-conotoxins from Conus striatus venom. Biochemistry. 31: 9919-26. PMID 1390774 DOI: 10.1021/bi00156a009  0.308
1990 Mena EE, Gullak MF, Pagnozzi MJ, Richter KE, Rivier J, Cruz LJ, Olivera BM. Conantokin-G: a novel peptide antagonist to the N-methyl-D-aspartic acid (NMDA) receptor. Neuroscience Letters. 118: 241-4. PMID 2177176 DOI: 10.1016/0304-3940(90)90637-O  0.379
1990 Myers RA, Mcintosh JM, Imperial J, Williams RW, Oas T, Haack JA, Hernandez JF, Rivier J, Cruz LJ, Olivera BM. Peptides from conus venoms which affect ca+plus; entry into neurons Toxin Reviews. 9: 179-202. DOI: 10.3109/15569549009033113  0.436
1989 Hillyard DR, Olivera BM, Woodward S, Corpuz GP, Gray WR, Ramilo CA, Cruz LJ. A molluscivorous Conus toxin: conserved frameworks in conotoxins. Biochemistry. 28: 358-61. PMID 2706261 DOI: 10.1021/Bi00427A049  0.383
1989 Cruz LJ, Kupryszewski G, LeCheminant GW, Gray WR, Olivera BM, Rivier J. mu-conotoxin GIIIA, a peptide ligand for muscle sodium channels: chemical synthesis, radiolabeling, and receptor characterization. Biochemistry. 28: 3437-42. PMID 2545259 DOI: 10.1021/Bi00434A043  0.384
1988 Zafaralla GC, Ramilo C, Gray WR, Karlstrom R, Olivera BM, Cruz LJ. Phylogenetic specificity of cholinergic ligands: alpha-conotoxin SI. Biochemistry. 27: 7102-5. PMID 3196703 DOI: 10.1021/Bi00418A065  0.324
1988 Gray WR, Olivera BM, Cruz LJ. Peptide toxins from venomous Conus snails. Annual Review of Biochemistry. 57: 665-700. PMID 3052286 DOI: 10.1146/Annurev.Bi.57.070188.003313  0.368
1988 Wagner JA, Guggino SE, Reynolds IJ, Snowman AM, Biswas A, Olivera BM, Snyder SH. Calcium antagonist receptors. Clinical and physiological relevance. Annals of the New York Academy of Sciences. 522: 116-33. PMID 2454047 DOI: 10.1111/J.1749-6632.1988.Tb33349.X  0.301
1988 Hirning LD, Fox AP, McCleskey EW, Olivera BM, Thayer SA, Miller RJ, Tsien RW. Dominant role of N-type Ca2+ channels in evoked release of norepinephrine from sympathetic neurons. Science (New York, N.Y.). 239: 57-61. PMID 2447647 DOI: 10.1126/Science.2447647  0.339
1987 Rivier J, Galyean R, Simon L, Cruz LJ, Olivera BM, Gray WR. Total synthesis and further characterization of the gamma-carboxyglutamate-containing "sleeper" peptide from Conus geographus venom. Biochemistry. 26: 8508-12. PMID 3442672 DOI: 10.1021/Bi00400A002  0.388
1987 Olivera BM, Cruz LJ, de Santos V, LeCheminant GW, Griffin D, Zeikus R, McIntosh JM, Galyean R, Varga J, Gray WR. Neuronal calcium channel antagonists. Discrimination between calcium channel subtypes using omega-conotoxin from Conus magus venom. Biochemistry. 26: 2086-90. PMID 2441741 DOI: 10.1021/Bi00382A004  0.41
1987 McCleskey EW, Fox AP, Feldman DH, Cruz LJ, Olivera BM, Tsien RW, Yoshikami D. Omega-conotoxin: direct and persistent blockade of specific types of calcium channels in neurons but not muscle. Proceedings of the National Academy of Sciences of the United States of America. 84: 4327-31. PMID 2438698 DOI: 10.1073/pnas.84.12.4327  0.366
1986 Reynolds IJ, Wagner JA, Snyder SH, Thayer SA, Olivera BM, Miller RJ. Brain voltage-sensitive calcium channel subtypes differentiated by omega-conotoxin fraction GVIA. Proceedings of the National Academy of Sciences of the United States of America. 83: 8804-7. PMID 2430302 DOI: 10.1073/Pnas.83.22.8804  0.32
1985 Olivera BM, Gray WR, Zeikus R, McIntosh JM, Varga J, Rivier J, de Santos V, Cruz LJ. Peptide neurotoxins from fish-hunting cone snails. Science (New York, N.Y.). 230: 1338-43. PMID 4071055 DOI: 10.1126/Science.4071055  0.429
1985 Cruz LJ, Gray WR, Yoshikami D, Olivera BM. Conus venoms: A rich source of neuroactive peptides Toxin Reviews. 4: 107-132. DOI: 10.3109/15569548509014416  0.43
1984 Gray WR, Luque FA, Galyean R, Atherton E, Sheppard RC, Stone BL, Reyes A, Alford J, McIntosh M, Olivera BM. Conotoxin GI: disulfide bridges, synthesis, and preparation of iodinated derivatives. Biochemistry. 23: 2796-802. PMID 6466616 DOI: 10.1021/Bi00307A040  0.388
1982 McIntosh M, Cruz LJ, Hunkapiller MW, Gray WR, Olivera BM. Isolation and structure of a peptide toxin from the marine snail Conus magus. Archives of Biochemistry and Biophysics. 218: 329-34. PMID 7149738 DOI: 10.1016/0003-9861(82)90351-4  0.411
1978 Cruz LJ, Gray WR, Olivera BM. Purification and properties of a myotoxin from Conus geographus venom. Archives of Biochemistry and Biophysics. 190: 539-48. PMID 718167 DOI: 10.1016/0003-9861(78)90308-9  0.326
1968 Wang JC, Baumgarten D, Olivera BM. On the origin of tertiary turns in covalently closed double-stranded cyclic DNA. Proceedings of the National Academy of Sciences of the United States of America. 58: 1852-8. PMID 4966262 DOI: 10.1073/Pnas.58.5.1852  0.422
1968 Olivera BM, Scheffler IE, Lehman IR. Enzymic joining of polynucleotides. IV. Formation of a circular deoxyadenylate-deoxythymidylate copolymer. Journal of Molecular Biology. 36: 275-85. PMID 4939627 DOI: 10.1016/0022-2836(68)90381-1  0.429
1968 Olivera BM, Lehman IR. Enzymic joining of polynucleotides. 3. The polydeoxyadenylate-polydeoxythymidylate homopolymer pair. Journal of Molecular Biology. 36: 261-74. PMID 4939626  0.424
1968 Olivera BM, Hall ZW, Anraku Y, Chien JR, Lehman IR. On the mechanism of the polynucleotide joining reaction. Cold Spring Harbor Symposia On Quantitative Biology. 33: 27-34. PMID 4306816 DOI: 10.1101/Sqb.1968.033.01.008  0.634
1968 Olivera BM, Hall ZW, Lehman IR. Enzymatic joining of polynucleotides, V. A DNA-adenylate intermediate in the polynucleotide-joining reaction. Proceedings of the National Academy of Sciences of the United States of America. 61: 237-44. PMID 4301588 DOI: 10.1073/Pnas.61.1.237  0.648
1967 Olivera BM, Lehman IR. Linkage of polynucleotides through phosphodiester bonds by an enzyme from Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 57: 1426-33. PMID 5341238 DOI: 10.1073/Pnas.57.5.1426  0.49
1967 Olivera BM, Lehman IR. Diphosphopyridine nucleotide: a cofactor for the polynucleotide-joining enzyme from Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 57: 1700-4. PMID 4291945 DOI: 10.1073/Pnas.57.6.1700  0.487
1967 Ohlenbusch HH, Olivera BM, Tuan D, Davidson N. Selective dissociation of histones from calf thymus nucleoprotein. Journal of Molecular Biology. 25: 299-315. PMID 4291873 DOI: 10.1016/0022-2836(67)90143-X  0.457
1965 DAVIDSON N, WIDHOLM J, NANDI US, JENSEN R, OLIVERA BM, WANG JC. PREPARATION AND PROPERTIES OF NATIVE CRAB DAT. Proceedings of the National Academy of Sciences of the United States of America. 53: 111-8. PMID 14283189 DOI: 10.1073/Pnas.53.1.111  0.569
1964 Olivera BM, Baine P, Davidson N. Electrophoresis of the nucleic acids Biopolymers. 2: 245-257. DOI: 10.1002/BIP.1964.360020306  0.457
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