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Christopher G. Parker - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wozniak JM, Li W, Governa P, Chen LY, Jadhav A, Dongre A, Forli S, Parker CG. Author Correction: Enhanced mapping of small-molecule binding sites in cells. Nature Chemical Biology. PMID 38212579 DOI: 10.1038/s41589-024-01546-z  0.728
2024 Chiu TY, Lazar DC, Wang WW, Wozniak JM, Jadhav AM, Li W, Gazaniga N, Theofilopoulos AN, Teijaro JR, Parker CG. Chemoproteomic development of SLC15A4 inhibitors with anti-inflammatory activity. Nature Chemical Biology. PMID 38191941 DOI: 10.1038/s41589-023-01527-8  0.779
2024 Wozniak JM, Li W, Governa P, Chen LY, Jadhav A, Dongre A, Forli S, Parker CG. Enhanced mapping of small-molecule binding sites in cells. Nature Chemical Biology. PMID 38167919 DOI: 10.1038/s41589-023-01514-z  0.763
2023 Forrest I, Parker CG. Proteome-Wide Fragment-Based Ligand and Target Discovery. Israel Journal of Chemistry. 63. PMID 38213795 DOI: 10.1002/ijch.202200098  0.758
2023 Wichroski M, Benci J, Liu SQ, Chupak L, Fang J, Cao C, Wang C, Onorato J, Qiu H, Shan Y, Banas D, Powles R, Locke G, Witt A, Stromko C, ... ... Parker CG, et al. DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell-mediated antitumor immunity. Science Translational Medicine. 15: eadh1892. PMID 37878674 DOI: 10.1126/scitranslmed.adh1892  0.447
2022 Chen LY, Wang WW, Wozniak JM, Parker CG. A heterobifunctional molecule system for targeted protein acetylation in cells. Methods in Enzymology. 681: 287-323. PMID 36764762 DOI: 10.1016/bs.mie.2022.08.014  0.763
2022 Hassan AA, Wozniak JM, Vilen Z, Li W, Jadhav A, Parker CG, Huang ML. Chemoproteomic mapping of human milk oligosaccharide (HMO) interactions in cells. Rsc Chemical Biology. 3: 1369-1374. PMID 36544572 DOI: 10.1039/d2cb00176d  0.781
2022 Homan RA, Jadhav AM, Conway LP, Parker CG. A Chemical Proteomic Map of Heme-Protein Interactions. Journal of the American Chemical Society. PMID 35960875 DOI: 10.1021/jacs.2c06104  0.775
2021 Wang WW, Chen LY, Wozniak JM, Jadhav AM, Anderson H, Malone TE, Parker CG. Targeted Protein Acetylation in Cells Using Heterobifunctional Molecules. Journal of the American Chemical Society. PMID 34592107 DOI: 10.1021/jacs.1c07850  0.771
2021 Vilen Z, Joeh E, Critcher M, Parker CG, Huang ML. Proximity Tagging Identifies the Glycan-Mediated Glycoprotein Interactors of Galectin-1 in Muscle Stem Cells. Acs Chemical Biology. PMID 34181849 DOI: 10.1021/acschembio.1c00313  0.41
2021 Conway LP, Jadhav AM, Homan RA, Li W, Rubiano JS, Hawkins R, Lawrence RM, Parker CG. Evaluation of fully-functionalized diazirine tags for chemical proteomic applications. Chemical Science. 12: 7839-7847. PMID 34168837 DOI: 10.1039/d1sc01360b  0.779
2021 Hong SH, Yoo DY, Conway L, Richards-Corke KC, Parker CG, Arora PS. A Sos proteomimetic as a pan-Ras inhibitor. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33926964 DOI: 10.1073/pnas.2101027118  0.243
2021 Joeh E, Reeves AE, Parker CG, Huang ML. Mapping Interactions between Glycans and Glycan-Binding Proteins by Live Cell Proximity Tagging. Current Protocols. 1: e104. PMID 33861898 DOI: 10.1002/cpz1.104  0.434
2021 Conway LP, Li W, Parker CG. Chemoproteomic-enabled phenotypic screening. Cell Chemical Biology. PMID 33577749 DOI: 10.1016/j.chembiol.2021.01.012  0.455
2020 Suresh BM, Li W, Zhang P, Wang KW, Yildirim I, Parker CG, Disney MD. A general fragment-based approach to identify and optimize bioactive ligands targeting RNA. Proceedings of the National Academy of Sciences of the United States of America. PMID 33318191 DOI: 10.1073/pnas.2012217117  0.388
2020 Joeh E, O'Leary T, Li W, Hawkins R, Hung JR, Parker CG, Huang ML. Mapping glycan-mediated galectin-3 interactions by live cell proximity labeling. Proceedings of the National Academy of Sciences of the United States of America. PMID 33067390 DOI: 10.1073/pnas.2009206117  0.462
2020 Parker CG, Pratt MR. Click Chemistry in Proteomic Investigations. Cell. PMID 32059777 DOI: 10.1016/J.Cell.2020.01.025  0.568
2019 Wang W, Gallo L, Jadhav A, Hawkins R, Parker CG. The Druggability of Solute Carriers. Journal of Medicinal Chemistry. PMID 31774679 DOI: 10.1021/Acs.Jmedchem.9B01237  0.751
2019 Galmozzi A, Kok BP, Kim AS, Montenegro-Burke JR, Lee JY, Spreafico R, Mosure S, Albert V, Cintron-Colon R, Godio C, Webb WR, Conti B, Solt LA, Kojetin D, Parker CG, et al. PGRMC2 is an intracellular haem chaperone critical for adipocyte function. Nature. PMID 31748741 DOI: 10.1038/S41586-019-1774-2  0.552
2019 Wang Y, Dix MM, Bianco G, Remsberg JR, Lee HY, Kalocsay M, Gygi SP, Forli S, Vite G, Lawrence RM, Parker CG, Cravatt BF. Expedited mapping of the ligandable proteome using fully functionalized enantiomeric probe pairs. Nature Chemistry. PMID 31659311 DOI: 10.1038/S41557-019-0351-5  0.792
2018 Galmozzi A, Parker CG, Kok BP, Cravatt BF, Saez E. Discovery of Modulators of Adipocyte Physiology Using Fully Functionalized Fragments. Methods in Molecular Biology (Clifton, N.J.). 1787: 115-127. PMID 29736714 DOI: 10.1007/978-1-4939-7847-2_9  0.602
2018 Parker CG, Cravatt BF. Chemistry Takes Center Stage for Identifying Cancer Targetability. Cell. 173: 815-817. PMID 29727668 DOI: 10.1016/J.Cell.2018.04.020  0.521
2017 Parker CG, Kuttruff CA, Galmozzi A, Jørgensen L, Yeh CH, Hermanson DJ, Wang Y, Artola M, McKerrall SJ, Josyln CM, Nørremark B, Dünstl G, Felding J, Saez E, Baran PS, et al. Chemical Proteomics Identifies SLC25A20 as a Functional Target of the Ingenol Class of Actinic Keratosis Drugs. Acs Central Science. 3: 1276-1285. PMID 29296668 DOI: 10.1021/Acscentsci.7B00420  0.641
2017 Schonhoft JD, Monteiro C, Plate L, Eisele YS, Kelly JM, Boland D, Parker CG, Cravatt BF, Teruya S, Helmke S, Maurer M, Berk J, Sekijima Y, Novais M, Coelho T, et al. Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients. Science Translational Medicine. 9. PMID 28904227 DOI: 10.1126/Scitranslmed.Aam7621  0.512
2017 Parker CG, Galmozzi A, Wang Y, Correia BE, Sasaki K, Joslyn CM, Kim AS, Cavallaro CL, Lawrence RM, Johnson SR, Narvaiza I, Saez E, Cravatt BF. Ligand and Target Discovery by Fragment-Based Screening in Human Cells. Cell. PMID 28111073 DOI: 10.1016/J.Cell.2016.12.029  0.731
2017 McEnaney PJ, Parker CG, Zhang AX. Chapter Thirteen - Antibody-Recruiting Small Molecules: Synthetic Constructs as Immunotherapeutics Annual Reports in Medicinal Chemistry. 50: 481-518. DOI: 10.1016/Bs.Armc.2017.08.008  0.79
2014 Parker CG, Dahlgren MK, Tao RN, Li DT, Douglass EF, Shoda T, Jawanda N, Spasov KA, Lee S, Zhou N, Domaoal RA, Sutton RE, Anderson KS, Jorgensen WL, Krystal M, et al. Illuminating HIV gp120-Ligand Recognition through Computationally-Driven Optimization of Antibody-Recruiting Molecules. Chemical Science (Royal Society of Chemistry : 2010). 5: 2311-2317. PMID 25379167 DOI: 10.1039/C4Sc00484A  0.731
2013 Jakobsche CE, Parker CG, Tao RN, Kolesnikova MD, Douglass EF, Spiegel DA. Exploring binding and effector functions of natural human antibodies using synthetic immunomodulators. Acs Chemical Biology. 8: 2404-11. PMID 24053626 DOI: 10.1021/Cb4004942  0.739
2012 McEnaney PJ, Parker CG, Zhang AX, Spiegel DA. Antibody-recruiting molecules: an emerging paradigm for engaging immune function in treating human disease. Acs Chemical Biology. 7: 1139-51. PMID 22758917 DOI: 10.1021/Cb300119G  0.774
2009 Parker CG, Domaoal RA, Anderson KS, Spiegel DA. An antibody-recruiting small molecule that targets HIV gp120. Journal of the American Chemical Society. 131: 16392-4. PMID 19839582 DOI: 10.1021/Ja9057647  0.553
2007 Garner P, Hu J, Parker CG, Youngs WJ, Medvetz D. The CuI-catalyzed exo-selective asymmetric multicomponent [C+NC+CC] coupling reaction Tetrahedron Letters. 48: 3867-3870. DOI: 10.1016/J.TETLET.2007.03.145  0.207
2007 Garner P, Hu J, Parker CG, Youngs WJ, Medvetz D. The CuI-catalyzed exo-selective asymmetric multicomponent [C+NC+CC] coupling reaction Tetrahedron Letters. 48: 3867-3870. DOI: 10.1016/J.Tetlet.2007.03.145  0.335
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