Edward J. Benz, Jr - Publications

Affiliations: 
Dana-Farber Cancer Institute Harvard Medical School, Boston, MA, United States 
Website:
http://www.dfhcc.harvard.edu/membership/profile/member/240/0/

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Huang SC, Zhang HS, Yu B, McMahon E, Nguyen DT, Yu FH, Ou AC, Park Ou J, Benz EJ. Protein 4.1R exon 16 3' splice site activation requires coordination among TIA1, Pcbp1, and RBM39 during terminal erythropoiesis. Molecular and Cellular Biology. PMID 28193846 DOI: 10.1128/Mcb.00446-16  0.34
2012 Huang SC, Ou AC, Park J, Yu F, Yu B, Lee A, Yang G, Zhou A, Benz EJ. RBFOX2 promotes protein 4.1R exon 16 selection via U1 snRNP recruitment. Molecular and Cellular Biology. 32: 513-26. PMID 22083953 DOI: 10.1128/Mcb.06423-11  0.312
2010 Benz EJ. Learning about genomics and disease from the anucleate human red blood cell. The Journal of Clinical Investigation. 120: 4204-6. PMID 21099106 DOI: 10.1172/Jci45433  0.314
2009 Huang SC, Cho A, Norton S, Liu ES, Park J, Zhou A, Munagala ID, Ou AC, Yang G, Wickrema A, Tang TK, Benz EJ. Coupled transcription-splicing regulation of mutually exclusive splicing events at the 5' exons of protein 4.1R gene. Blood. 114: 4233-42. PMID 19729518 DOI: 10.1182/Blood-2009-02-206219  0.336
2009 Huang S, Yang G, Park J, Ou A, Benz EJ. Fox-2A Modulates Protein 4.1R Exon 16 5' Splice Site Activation. Blood. 114: 778-778. DOI: 10.1182/Blood.V114.22.778.778  0.305
2008 Zhou A, Ou AC, Cho A, Benz EJ, Huang SC. Novel splicing factor RBM25 modulates Bcl-x pre-mRNA 5' splice site selection. Molecular and Cellular Biology. 28: 5924-36. PMID 18663000 DOI: 10.1128/Mcb.00560-08  0.31
2008 Yang G, Huang SC, Wu JY, Benz EJ. Regulated Fox-2 isoform expression mediates protein 4.1R splicing during erythroid differentiation Blood. 111: 392-401. PMID 17715393 DOI: 10.1182/Blood-2007-01-068940  0.327
2007 Zhou A, Cho A, Huang S, Benz EJ. A Novel Splicing Factor RBM25 in Erythroid Differentiation. Blood. 110: 1711-1711. DOI: 10.1182/Blood.V110.11.1711.1711  0.326
2005 Yang G, Huang SC, Wu JY, Benz EJ. An erythroid differentiation-specific splicing switch in protein 4.1R mediated by the interaction SF2/ASF with an exonic splicing enhancer Blood. 105: 2146-2153. PMID 15522963 DOI: 10.1182/Blood-2004-05-1757  0.358
2005 Yang G, Huang S, Benz EJ. A Novel Splicing Factor RBM-9 Regulates Protein 4.1R Exon 16 Splicing. Blood. 106: 805-805. DOI: 10.1182/Blood.V106.11.805.805  0.367
2005 Huang S, Norton SM, Liu ES, AnYu Z, Guang Y, Benz EJ. Regulation of Exon 2′/2 of Protein 4.1R by Coordinated Transcription and Splicing. Blood. 106: 1663-1663. DOI: 10.1182/Blood.V106.11.1663.1663  0.327
2002 Delhommeau F, Vasseur-Godbillon C, Leclerc P, Schischmanoff PO, Croisille L, Rince P, Morinière M, Benz EJ, Tchernia G, Tamagnini G, Ribeiro L, Delaunay J, Baklouti F. A splicing alteration of 4.1R pre-mRNA generates 2 protein isoforms with distinct assembly to spindle poles in mitotic cells. Blood. 100: 2629-36. PMID 12239178 DOI: 10.1182/Blood.V100.7.2629  0.333
2002 Deguillien M, Huang SC, Morinière M, Dreumont N, Benz EJ, Baklouti F. Multiple cis elements regulate an alternative splicing event at 4.1R pre-mRNA during erythroid differentiation. Blood. 98: 3809-16. PMID 11739190 DOI: 10.1182/Blood.V98.13.3809  0.345
2001 Huang S, Lichtenauer UD, Pack S, Wang C, Kim AC, Lutchman M, Koch CA, Torres-Cruz J, Huang SC, Benz EJ, Christiansen H, Dockhorn-Dworniczak B, Poremba C, Vortmeyer AO, Chishti AH, et al. Reassignment of the EPB4.1 gene to 1p36 and assessment of its involvement in neuroblastomas European Journal of Clinical Investigation. 31: 907-914. PMID 11737230 DOI: 10.1046/J.1365-2362.2001.00892.X  0.335
2000 Devarajan P, Benz EJ. Translational regulation of Na-K-ATPase subunit mRNAs by glucocorticoids. American Journal of Physiology. Renal Physiology. 279: F1132-8. PMID 11097633 DOI: 10.1152/Ajprenal.2000.279.6.F1132  0.43
1997 Baklouti F, Huang SC, Vulliamy TJ, Delaunay J, Benz EJ. Organization of the human protein 4.1 genomic locus: new insights into the tissue-specific alternative splicing of the pre-mRNA. Genomics. 39: 289-302. PMID 9119366 DOI: 10.1006/Geno.1996.4512  0.358
1996 Zahler R, Gilmore-Hebert M, Sun W, Benz EJ. Na, K-ATPase isoform gene expression in normal and hypertrophied dog heart Basic Research in Cardiology. 91: 256-266. PMID 8831945 DOI: 10.1007/Bf00788912  0.35
1994 Xu JC, Lytle C, Zhu TT, Payne JA, Benz E, Forbush B. Molecular cloning and functional expression of the bumetanide-sensitive Na-K-Cl cotransporter Proceedings of the National Academy of Sciences of the United States of America. 91: 2201-2205. PMID 8134373 DOI: 10.1073/Pnas.91.6.2201  0.381
1993 Horne WC, Huang SC, Becker PS, Tang TK, Benz EJ. Tissue-specific alternative splicing of protein 4.1 inserts an exon necessary for formation of the ternary complex with erythrocyte spectrin and F-actin. Blood. 82: 2558-63. PMID 8400303 DOI: 10.1182/Blood.V82.8.2558.2558  0.343
1993 Zahler R, Gilmore-Hebert M, Baldwin JC, Franco K, Benz EJ. Expression of α isoforms of the Na,K-ATPase in human heart Bba - Biomembranes. 1149: 189-194. PMID 8391840 DOI: 10.1016/0005-2736(93)90200-J  0.314
1992 Johnston JJ, Rintels P, Chung J, Sather J, Benz EJ, Berliner N. Lactoferrin gene promoter: structural integrity and nonexpression in HL60 cells. Blood. 79: 2998-3006. PMID 1586744 DOI: 10.1182/Blood.V79.11.2998.Bloodjournal79112998  0.352
1992 Baserga SJ, Benz EJ. Beta-globin nonsense mutation: deficient accumulation of mRNA occurs despite normal cytoplasmic stability. Proceedings of the National Academy of Sciences of the United States of America. 89: 2935-9. PMID 1557399 DOI: 10.1073/Pnas.89.7.2935  0.633
1992 Dalla Venezia N, Gilsanz F, Alloisio N, Ducluzeau MT, Benz EJ, Delaunay J. Homozygous 4.1(-) hereditary elliptocytosis associated with a point mutation in the downstream initiation codon of protein 4.1 gene. The Journal of Clinical Investigation. 90: 1713-7. PMID 1430200 DOI: 10.1172/Jci116044  0.314
1992 Kolansky DM, Brines ML, Gilmore-Hebert M, Benz EJ. The A2 isoform of rat Na+,K(+)-adenosine triphosphatase is active and exhibits high ouabain affinity when expressed in transfected fibroblasts. Febs Letters. 303: 147-53. PMID 1376695 DOI: 10.1016/0014-5793(92)80507-D  0.329
1992 Devarajan P, Gilmore-Hebert M, Benz EJ. Differential translation of the Na,K-ATPase subunit mRNAs. The Journal of Biological Chemistry. 267: 22435-9. PMID 1331056  0.331
1992 Chambers SK, Gilmore-Hebert M, Kacinski BM, Benz EJ. Changes in Na,K-ATPase gene expression during granulocytic differentiation of HL60 cells. Blood. 80: 1559-64. PMID 1325845 DOI: 10.1182/Blood.V80.6.1559.Bloodjournal8061559  0.367
1992 Feddal S, Hayette S, Baklouti F, Rimokh R, Wilmotte R, Magaud J, Maréchal J, Benz E, Girot R, Delaunay J, Morlé L. Prevalent skipping of an individual exon accounts for shortened protein 4.1 Presles Blood. 80: 2925-2930. DOI: 10.1182/Blood.V80.11.2925.2925  0.321
1991 Vignery A, Wang F, Qian HY, Benz EJ, Gilmore-Hebert M. Detection of the Na(+)-K(+)-ATPase alpha 3-isoform in multinucleated macrophages. The American Journal of Physiology. 260: F704-9. PMID 1852120 DOI: 10.1152/Ajprenal.1991.260.5.F704  0.381
1991 Takeshita K, Benz EJ. Gene expression during erythropoiesis. International Journal of Cell Cloning. 9: 109-22. PMID 1645390 DOI: 10.1002/Stem.5530090202  0.329
1991 Kolansky DM, Gilmore-Heben M, Brines ML, Benz EJ. High affinity ouabain binding of the alpha 2 isoform of Na,K-ATPase in transfected mammalian cells Journal of the American College of Cardiology. 17: A140. DOI: 10.1016/0735-1097(91)91527-L  0.337
1991 Zahler R, Brines M, Kashgarian M, Benz EJ, Gilmore-Hebert M. The cardiac conduction system in the rat expresses the α3 isoform of the Na,K-ATPase Journal of the American College of Cardiology. 17: A101. DOI: 10.1016/0735-1097(91)91370-T  0.302
1990 Váradi A, Gilmore-Heber M, Benz EJ. Amplification of the phosphorylation site-ATP-binding site cDNA fragment of the Na+,K(+)-ATPase and the Ca2(+)-ATPase of Drosophila melanogaster by polymerase chain reaction. Febs Letters. 258: 203-7. PMID 2557235 DOI: 10.1016/0014-5793(89)81653-9  0.326
1990 Tang TK, Qin Z, Leto T, Marchesi VT, Benz EJ. Heterogeneity of mRNA and protein products arising from the protein 4.1 gene in erythroid and nonerythroid tissues. The Journal of Cell Biology. 110: 617-24. PMID 2307701 DOI: 10.1083/Jcb.110.3.617  0.387
1990 Magnus T, Baserga SJ, Stolle C, Takeshita K, Benz EJ. Metabolism of non-translatable globin mRNAs arising from premature translation termination codons. Annals of the New York Academy of Sciences. 612: 55-66. PMID 2291574 DOI: 10.1111/J.1749-6632.1990.Tb24290.X  0.599
1989 Gilmore-Hebert M, Schneider JW, Greene AL, Berliner N, Stolle CA, Lomax K, Mercer RW, Benz EJ. Expression of multiple Na+,K+-adenosine triphosphatase isoform genes in human hematopoietic cells. Behavior of the novel A3 isoform during induced maturation of HL60 cells. The Journal of Clinical Investigation. 84: 347-51. PMID 2544628 DOI: 10.1172/Jci114161  0.686
1989 Lomax KJ, Gallin JI, Rotrosen D, Raphael GD, Kaliner MA, Benz EJ, Boxer LA, Malech HL. Selective defect in myeloid cell lactoferrin gene expression in neutrophil specific granule deficiency. The Journal of Clinical Investigation. 83: 514-9. PMID 2536400 DOI: 10.1172/Jci113912  0.326
1988 Tang TK, Leto TL, Correas I, Alonso MA, Marchesi VT, Benz EJ. Selective expression of an erythroid-specific isoform of protein 4.1. Proceedings of the National Academy of Sciences of the United States of America. 85: 3713-7. PMID 3375238 DOI: 10.1073/Pnas.85.11.3713  0.394
1988 Baserga SJ, Benz EJ. Nonsense mutations in the human beta-globin gene affect mRNA metabolism. Proceedings of the National Academy of Sciences of the United States of America. 85: 2056-60. PMID 3353367 DOI: 10.1073/Pnas.85.7.2056  0.617
1988 Leto TL, Fortugno-Erikson D, Barton D, Yang-Feng TL, Francke U, Harris AS, Morrow JS, Marchesi VT, Benz EJ. Comparison of nonerythroid alpha-spectrin genes reveals strict homology among diverse species. Molecular and Cellular Biology. 8: 1-9. PMID 3336352 DOI: 10.1128/Mcb.8.1.1  0.346
1988 Tang TK, Leto TL, Marchesi VT, Benz EJ. Expression of specific isoforms of protein 4.1 in erythroid and non-erythroid tissues. Advances in Experimental Medicine and Biology. 241: 81-95. PMID 3223413 DOI: 10.1007/978-1-4684-5571-7_12  0.376
1988 Stolle CA, Benz EJ. Cellular factor affecting the stability of beta-globin mRNA. Gene. 62: 65-74. PMID 3163661 DOI: 10.1016/0378-1119(88)90580-X  0.379
1988 Yang-Feng TL, Schneider JW, Lindgren V, Shull MM, Benz EJ, Lingrel JB, Francke U. Chromosomal localization of human Na+, K+-ATPase alpha- and beta-subunit genes. Genomics. 2: 128-38. PMID 2842249 DOI: 10.1016/0888-7543(88)90094-8  0.353
1988 Schneider JW, Mercer RW, Benz EJ, Levenson R. Molecular cloning of Na+,K+-ATPase alpha subunit gene using antibody probes. Methods in Enzymology. 156: 379-92. PMID 2835621 DOI: 10.1016/0076-6879(88)56038-X  0.661
1988 Schneider JW, Mercer RW, Gilmore-Hebert M, Utset MF, Lai C, Greene A, Benz EJ. Tissue specificity, localization in brain, and cell-free translation of mRNA encoding the A3 isoform of Na+,K+-ATPase. Proceedings of the National Academy of Sciences of the United States of America. 85: 284-8. PMID 2829175 DOI: 10.1073/Pnas.85.1.284  0.674
1987 High KA, Stolle CA, Schneider JW, Hu W, Benz EJ. c-myc Gene inactivation during induced maturation of HL-60 cells. Transcriptional repression and loss of a specific DNAse I hypersensitive site Journal of Clinical Investigation. 79: 93-99. PMID 3540012 DOI: 10.1172/Jci112814  0.502
1987 Schneider JW, Mercer RW, Emanuel J, Levenson RM, Benz EJ. Expression of genes for the alpha and beta subunits of the Na,K-ATPase in normal and drug resistant cells. Blood Cells. 13: 299-307. PMID 2822179  0.32
1987 Rado T, Wei X, Benz EJ. Isolation of lactoferrin cDNA from a human myeloid library and expression of mRNA during normal and leukemic myelopoiesis Blood. 70: 989-993. DOI: 10.1182/Blood.V70.4.989.989  0.387
1986 Mercer RW, Schneider JW, Savitz A, Emanuel J, Benz EJ, Levenson R. Rat-brain Na,K-ATPase beta-chain gene: primary structure, tissue-specific expression, and amplification in ouabain-resistant HeLa C+ cells. Molecular and Cellular Biology. 6: 3884-90. PMID 3025616 DOI: 10.1128/Mcb.6.11.3884  0.684
1986 Emanuel JR, Garetz S, Schneider J, Ash JF, Benz EJ, Levenson R. Amplification of DNA sequences coding for the Na,K-ATPase alpha-subunit in ouabain-resistant C+ cells. Molecular and Cellular Biology. 6: 2476-81. PMID 3023935 DOI: 10.1128/Mcb.6.7.2476  0.385
1985 Baserga SJ, Linnenbach AJ, Malcolm S, Ghosh P, Malcolm AD, Takeshita K, Forget BG, Benz EJ. Polyadenylation of a human mitochondrial ribosomal RNA transcript detected by molecular cloning. Gene. 35: 305-12. PMID 4043734 DOI: 10.1016/0378-1119(85)90009-5  0.596
1985 Lambert SR, High KA, Benz EJ, Cotlier E. Serous Retinal Detachments in Thrombotic Thrombocytopenic Purpura Archives of Ophthalmology. 103: 1172-1174. PMID 4040743 DOI: 10.1001/Archopht.1985.01050080084026  0.427
1985 Takeshita K, Benz EJ. Analysis of gene expression during hematopoiesis: present and future applications. Critical Reviews in Oncology/Hematology. 4: 67-102. PMID 3902264 DOI: 10.1016/S1040-8428(85)80020-2  0.313
1985 Schneider JW, Mercer RW, Caplan M, Emanuel JR, Sweadner KJ, Benz EJ, Levenson R. Molecular cloning of rat brain Na,K-ATPase alpha-subunit cDNA. Proceedings of the National Academy of Sciences of the United States of America. 82: 6357-61. PMID 2994074 DOI: 10.1073/Pnas.82.18.6357  0.687
1985 Benz EJ, Takeshita K, Scarpa AL. Metabolism of structurally abnormal mRNAs resulting from beta-thalassemia mutations. Annals of the New York Academy of Sciences. 445: 57-67. PMID 2990305 DOI: 10.1111/J.1749-6632.1985.Tb17175.X  0.33
1984 Benz EJ, Pritchard J, Hillman D, Glass J, Forget BG. Beta globin messenger RNA content of bone marrow erythroblasts in heterozygous beta-thalassemia. American Journal of Hematology. 16: 33-45. PMID 6695907 DOI: 10.1002/Ajh.2830160105  0.36
1982 Fukumaki Y, Ghosh PK, Benz EJ, Reddy VB, Lebowitz P, Forget BG, Weissman SM. Abnormally spliced messenger RNA in erythroid cells from patients with β+ thalassemia and monkey cells expressing a cloned β+-thalassemic gene Cell. 28: 585-593. PMID 6280877 DOI: 10.1016/0092-8674(82)90213-6  0.389
1982 Tonkonow B, Hoffman R, Burger D, Elder J, Mazur E, Murnane M, Benz EJ. Differing responses of globin and glycophorin gene expression to hemin in the human leukemia cell line K562 Blood. 59: 738-746. DOI: 10.1182/Blood.V59.4.738.Bloodjournal594738  0.377
1981 Benz EJ, Scarpa AL, Tonkonow BL, Pearson HA, Ritchey AK. Posttranscriptional defects in β-globin messenger RNA metabolism in β-thalassemia. Abnormal accumulation of β-messenger RNA precursor sequences Journal of Clinical Investigation. 68: 1529-1538. PMID 7320200 DOI: 10.1172/Jci110407  0.394
1981 Benz EJ, Berman BW, Tonkonow BL, Coupal E, Coates T, Boxer LA, Altman A, Adams JG. Molecular analysis of the beta-thalassemia phenotype associated with inheritance of hemoglobin E (alpha 2 beta2(26)Glu leads to Lys). The Journal of Clinical Investigation. 68: 118-26. PMID 6166632 DOI: 10.1172/Jci110226  0.332
1981 Adams JG, Steinberg MH, Newman MV, Morrison WT, Benz EJ, Iyer R. beta-Thalassemia present in cis to a new beta-chain structural variant, Hb Vicksburg [beta 75 (E19)Leu leads to 0]. Proceedings of the National Academy of Sciences of the United States of America. 78: 469-73. PMID 6165992 DOI: 10.1073/Pnas.78.1.469  0.331
1980 Benz EJ, Murnane MJ, Tonkonow BL, Berman BW, Mazur EM, Cavallesco C, Jenko T, Snyder EL, Forget BG, Hoffman R. Embryonic-fetal erythroid characteristics of a human leukemic cell line. Proceedings of the National Academy of Sciences of the United States of America. 77: 3509-13. PMID 6932034 DOI: 10.1073/Pnas.77.6.3509  0.317
1978 Benz EJ, Forget BG, Hillman DG, Cohen-Solal M, Pritchard J, Cavallesco C, Prensky W, Housman D. Variability in the amount of beta-globin mRNA in beta0 thalassemia. Cell. 14: 299-312. PMID 667942 DOI: 10.1016/0092-8674(78)90116-2  0.378
1978 Forget BG, Cavallesco C, Benz EJ, McClure PD, Hillman DG, Krieger H, Clarke B, Housman D. Studies of globin chain synthesis and globin mRNA content in a patient homozygous for hemoglobin Lepore. Hemoglobin. 2: 117-28. PMID 640850 DOI: 10.3109/03630267809074779  0.403
1978 Young NS, Benz EJ, Kantor JA, Kretschmer P, Nienhuis AW. Hemoglobin switching in sheep: only the gamma gene is in the active conformation in fetal liver but all the beta and gamma genes are in the active conformation in bone marrow. Proceedings of the National Academy of Sciences of the United States of America. 75: 5884-8. PMID 282609 DOI: 10.1073/Pnas.75.12.5884  0.371
1977 Benz E, Turner P, Barker J, Nienhuis A. Stability of the individual globin genes during erythroid differentiation. Science (New York, N.Y.). 196: 1213-4. PMID 860136 DOI: 10.1126/Science.860136  0.302
1977 Nienhuis AW, Benz EJ. Regulation of hemoglobin synthesis during the development of the red cell (first of three parts). The New England Journal of Medicine. 297: 1318-28. PMID 335250 DOI: 10.1056/Nejm197712152972404  0.304
1977 Nienhuis AW, Turner P, Benz EJ. Relative stability of alpha- and beta-globin messenger RNAs in homozygous beta+ thalassemia. Proceedings of the National Academy of Sciences of the United States of America. 74: 3960-4. PMID 71735 DOI: 10.1073/Pnas.74.9.3960  0.387
1976 Forget BG, Hillman DG, Lazarus H, Barell EF, Benz EJ, Caskey CT, Hulsman THJ, Schroeder WA, Housman D. Absence of messenger RNA and gene DNA for β-globin chains in hereditary persistence of fetal hemoglobin Cell. 7: 323-329. PMID 947544 DOI: 10.1016/0092-8674(76)90161-6  0.314
1975 Housman D, Skoultchi A, Forget BG, Benz EJ. Use of globin cDNA as a hybridization probe for globin mRNA. Annals of the New York Academy of Sciences. 241: 280-9. PMID 4139921 DOI: 10.1111/J.1749-6632.1974.Tb21887.X  0.341
1975 Benz EJ, Swerdlow P, Forget B. Absence of functional messenger RNA activity for beta globin chain synthesis in beta 0-thalassemia Blood. 45: 1-10. DOI: 10.1182/Blood.V45.1.1.Bloodjournal4511  0.346
1973 Housman D, Forget BG, Skoultchi A, Benz EJ. Quantitative deficiency of chain-specific globin messenger ribonucleic acids in the thalassemia syndromes. Proceedings of the National Academy of Sciences of the United States of America. 70: 1809-13. PMID 4124305 DOI: 10.1073/Pnas.70.6.1809  0.397
1973 Benz EJ, Swerdlow PS, Forget BG. Globin Messenger RNA in Hemoglobin H Disease Blood. 42: 825-833. DOI: 10.1182/Blood.V42.6.825.825  0.323
1972 Benz EJ, Forget BG. Defect in messenger RNA for human hemoglobin synthesis in beta thalassemia. The Journal of Clinical Investigation. 50: 2755-60. PMID 5129324 DOI: 10.1172/Jci106778  0.348
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