Hyun B Choi, Ph.D - Publications

2006- Psychiatry University of British Columbia, Vancouver, Vancouver, BC, Canada 
Neuroscience, Brain metabolism

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 York EM, Zhang J, Choi HB, MacVicar BA. Neuroinflammatory inhibition of synaptic long-term potentiation requires immunometabolic reprogramming of microglia. Glia. PMID 32946147 DOI: 10.1002/glia.23913  1
2020 Bernier LP, York EM, Kamyabi A, Choi HB, Weilinger NL, MacVicar BA. Microglial metabolic flexibility supports immune surveillance of the brain parenchyma. Nature Communications. 11: 1559. PMID 32214088 DOI: 10.1038/S41467-020-15267-Z  1
2019 Bernier LP, Bohlen CJ, York EM, Choi HB, Kamyabi A, Dissing-Olesen L, Hefendehl JK, Collins HY, Stevens B, Barres BA, MacVicar BA. Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia. Cell Reports. 27: 2895-2908.e4. PMID 31167136 DOI: 10.1016/J.Celrep.2019.05.010  1
2017 MacVicar BA, Choi HB. Astrocytes Provide Metabolic Support for Neuronal Synaptic Function in Response to Extracellular K(). Neurochemical Research. PMID 28664400 DOI: 10.1007/s11064-017-2315-8  1
2017 Howarth C, Sutherland BA, Choi HB, Martin C, Lind BL, Khennouf L, LeDue JM, Pakan JM, Ko RW, Ellis-Davies GC, Lauritzen MJ, Sibson NR, Buchan AM, MacVicar BA. A critical role for astrocytes in hypercapnic vasodilation in brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28137973 DOI: 10.1523/Jneurosci.0005-16.2016  1
2015 Ryu JK, Cho T, Choi HB, Jantaratnotai N, McLarnon JG. Pharmacological antagonism of interleukin-8 receptor CXCR2 inhibits inflammatory reactivity and is neuroprotective in an animal model of Alzheimer's disease. Journal of Neuroinflammation. 12: 144. PMID 26255110 DOI: 10.1186/S12974-015-0339-Z  1
2015 Rungta RL, Choi HB, Tyson JR, Malik A, Dissing-Olesen L, Lin PJ, Cain SM, Cullis PR, Snutch TP, MacVicar BA. The cellular mechanisms of neuronal swelling underlying cytotoxic edema. Cell. 161: 610-21. PMID 25910210 DOI: 10.1016/J.Cell.2015.03.029  1
2014 Dissing-Olesen L, LeDue JM, Rungta RL, Hefendehl JK, Choi HB, MacVicar BA. Activation of neuronal NMDA receptors triggers transient ATP-mediated microglial process outgrowth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 10511-27. PMID 25100586 DOI: 10.1523/JNEUROSCI.0405-14.2014  1
2014 Zhang J, Malik A, Choi HB, Ko RW, Dissing-Olesen L, MacVicar BA. Microglial CR3 activation triggers long-term synaptic depression in the hippocampus via NADPH oxidase. Neuron. 82: 195-207. PMID 24631344 DOI: 10.1016/j.neuron.2014.01.043  1
2014 Hashioka S, Wang YF, Little JP, Choi HB, Klegeris A, McGeer PL, McLarnon JG. Purinergic responses of calcium-dependent signaling pathways in cultured adult human astrocytes. Bmc Neuroscience. 15: 18. PMID 24447580 DOI: 10.1186/1471-2202-15-18  1
2013 Rungta RL, Choi HB, Lin PJ, Ko RW, Ashby D, Nair J, Manoharan M, Cullis PR, Macvicar BA. Lipid Nanoparticle Delivery of siRNA to Silence Neuronal Gene Expression in the Brain. Molecular Therapy. Nucleic Acids. 2: e136. PMID 24301867 DOI: 10.1038/Mtna.2013.65  1
2013 Hines DJ, Choi HB, Hines RM, Phillips AG, MacVicar BA. Prevention of LPS-induced microglia activation, cytokine production and sickness behavior with TLR4 receptor interfering peptides. Plos One. 8: e60388. PMID 23555964 DOI: 10.1371/Journal.Pone.0060388  1
2013 Fordsmann JC, Ko RW, Choi HB, Thomsen K, Witgen BM, Mathiesen C, Lønstrup M, Piilgaard H, MacVicar BA, Lauritzen M. Increased 20-HETE synthesis explains reduced cerebral blood flow but not impaired neurovascular coupling after cortical spreading depression in rat cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2562-70. PMID 23392684 DOI: 10.1523/JNEUROSCI.2308-12.2013  1
2012 Choi HB, Gordon GR, Zhou N, Tai C, Rungta RL, Martinez J, Milner TA, Ryu JK, McLarnon JG, Tresguerres M, Levin LR, Buck J, MacVicar BA. Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase. Neuron. 75: 1094-104. PMID 22998876 DOI: 10.1016/J.Neuron.2012.08.032  1
2011 Robillard JM, Gordon GR, Choi HB, Christie BR, MacVicar BA. Glutathione restores the mechanism of synaptic plasticity in aged mice to that of the adult. Plos One. 6: e20676. PMID 21655192 DOI: 10.1371/Journal.Pone.0020676  1
2011 Tai C, Hines DJ, Choi HB, MacVicar BA. Plasma membrane insertion of TRPC5 channels contributes to the cholinergic plateau potential in hippocampal CA1 pyramidal neurons. Hippocampus. 21: 958-67. PMID 20865744 DOI: 10.1002/hipo.20807  1
2009 Jantaratnotai N, Choi HB, McLarnon JG. ATP stimulates chemokine production via a store-operated calcium entry pathway in C6 glioma cells. Bmc Cancer. 9: 442. PMID 20003523 DOI: 10.1186/1471-2407-9-442  1
2009 Ryu JK, Cho T, Choi HB, Wang YT, McLarnon JG. Microglial VEGF receptor response is an integral chemotactic component in Alzheimer's disease pathology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 3-13. PMID 19129379 DOI: 10.1523/Jneurosci.2888-08.2009  1
2008 Gordon GR, Choi HB, Rungta RL, Ellis-Davies GC, MacVicar BA. Brain metabolism dictates the polarity of astrocyte control over arterioles. Nature. 456: 745-9. PMID 18971930 DOI: 10.1038/nature07525  1
2008 Kim SU, Nagai A, Nakagawa E, Choi HB, Bang JH, Lee HJ, Lee MA, Lee YB, Park IH. Production and characterization of immortal human neural stem cell line with multipotent differentiation property. Methods in Molecular Biology (Clifton, N.J.). 438: 103-21. PMID 18369753 DOI: 10.1007/978-1-59745-133-8_10  1
2008 Wei W, Ryu JK, Choi HB, McLarnon JG. Expression and function of the P2X(7) receptor in rat C6 glioma cells. Cancer Letters. 260: 79-87. PMID 18039556 DOI: 10.1016/j.canlet.2007.10.025  1
2007 Klegeris A, Choi HB, McLarnon JG, McGeer PL. Functional ryanodine receptors are expressed by human microglia and THP-1 cells: Their possible involvement in modulation of neurotoxicity. Journal of Neuroscience Research. 85: 2207-15. PMID 17526017 DOI: 10.1002/Jnr.21361  1
2007 Choi HB, Ryu JK, Kim SU, McLarnon JG. Modulation of the purinergic P2X7 receptor attenuates lipopolysaccharide-mediated microglial activation and neuronal damage in inflamed brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 4957-68. PMID 17475804 DOI: 10.1523/JNEUROSCI.5417-06.2007  1
2007 Lee HJ, Kim KS, Kim EJ, Choi HB, Lee KH, Park IH, Ko Y, Jeong SW, Kim SU. Brain transplantation of immortalized human neural stem cells promotes functional recovery in mouse intracerebral hemorrhage stroke model. Stem Cells (Dayton, Ohio). 25: 1204-12. PMID 17218400 DOI: 10.1634/stemcells.2006-0409  1
2006 Franciosi S, Ryu JK, Choi HB, Radov L, Kim SU, McLarnon JG. Broad-spectrum effects of 4-aminopyridine to modulate amyloid beta1-42-induced cell signaling and functional responses in human microglia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11652-64. PMID 17093087 DOI: 10.1523/JNEUROSCI.2490-06.2006  1
2006 McLarnon JG, Ryu JK, Walker DG, Choi HB. Upregulated expression of purinergic P2X(7) receptor in Alzheimer disease and amyloid-beta peptide-treated microglia and in peptide-injected rat hippocampus. Journal of Neuropathology and Experimental Neurology. 65: 1090-7. PMID 17086106 DOI: 10.1097/01.jnen.0000240470.97295.d3  1
2006 Kim SU, Park IH, Kim TH, Kim KS, Choi HB, Hong SH, Bang JH, Lee MA, Joo IS, Lee CS, Kim YS. Brain transplantation of human neural stem cells transduced with tyrosine hydroxylase and GTP cyclohydrolase 1 provides functional improvement in animal models of Parkinson disease. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 26: 129-40. PMID 16708545 DOI: 10.1111/J.1440-1789.2006.00688.X  1
2006 Hong SH, Choi HB, Kim SU, McLarnon JG. Mitochondrial ligand inhibits store-operated calcium influx and COX-2 production in human microglia. Journal of Neuroscience Research. 83: 1293-8. PMID 16547968 DOI: 10.1002/jnr.20829  1
2005 McLarnon JG, Choi HB, Lue LF, Walker DG, Kim SU. Perturbations in calcium-mediated signal transduction in microglia from Alzheimer's disease patients. Journal of Neuroscience Research. 81: 426-35. PMID 15948178 DOI: 10.1002/jnr.20487  1
2005 Ryu JK, Choi HB, McLarnon JG. Peripheral benzodiazepine receptor ligand PK11195 reduces microglial activation and neuronal death in quinolinic acid-injected rat striatum. Neurobiology of Disease. 20: 550-61. PMID 15916899 DOI: 10.1016/j.nbd.2005.04.010  1
2005 Sattayaprasert P, Choi HB, Chongthammakun S, McLarnon JG. Platelet-activating factor enhancement of calcium influx and interleukin-6 expression, but not production, in human microglia. Journal of Neuroinflammation. 2: 11. PMID 15833109 DOI: 10.1186/1742-2094-2-11  1
2005 Franciosi S, Choi HB, Kim SU, McLarnon JG. IL-8 enhancement of amyloid-beta (Abeta 1-42)-induced expression and production of pro-inflammatory cytokines and COX-2 in cultured human microglia. Journal of Neuroimmunology. 159: 66-74. PMID 15652404 DOI: 10.1016/j.jneuroim.2004.10.006  1
2004 Ryu JK, Kim J, Cho SJ, Hatori K, Nagai A, Choi HB, Lee MC, McLarnon JG, Kim SU. Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease. Neurobiology of Disease. 16: 68-77. PMID 15207263 DOI: 10.1016/j.nbd.2004.01.016  1
2003 Choi HB, Hong SH, Ryu JK, Kim SU, McLarnon JG. Differential activation of subtype purinergic receptors modulates Ca(2+) mobilization and COX-2 in human microglia. Glia. 43: 95-103. PMID 12838502 DOI: 10.1002/glia.10239  1
2003 Ryu JK, Choi HB, Hatori K, Heisel RL, Pelech SL, McLarnon JG, Kim SU. Adenosine triphosphate induces proliferation of human neural stem cells: Role of calcium and p70 ribosomal protein S6 kinase. Journal of Neuroscience Research. 72: 352-62. PMID 12692902 DOI: 10.1002/Jnr.10507  1
2002 Franciosi S, Choi HB, Kim SU, McLarnon JG. Interferon-gamma acutely induces calcium influx in human microglia. Journal of Neuroscience Research. 69: 607-13. PMID 12210826 DOI: 10.1002/jnr.10331  1
2002 Cho T, Bae JH, Choi HB, Kim SS, McLarnon JG, Suh-Kim H, Kim SU, Min CK. Human neural stem cells: electrophysiological properties of voltage-gated ion channels Neuroreport.. 13: 1447-52.  1
2002 Choi HB, Khoo C, Ryu JK, van Breemen E, Kim SU, McLarnon JG. Inhibition of lipopolysaccharide-induced cyclooxygenase-2, tumor necrosis factor-alpha and [Ca2+]i responses in human microglia by the peripheral benzodiazepine receptor ligand PK11195 J Neurochem. 83: 546-55.  1
2001 Khoo C, Helm J, Choi HB, Kim SU, McLarnon JG. Inhibition of store-operated Ca(2+) influx by acidic extracellular pH in cultured human microglia Glia. 22-30. DOI: 10.1002/Glia.1092  1
2001 McLarnon JG, Franciosi S, Wang X, Bae JH, Choi HB, Kim SU. Acute actions of tumor necrosis factor-alpha on intracellular Ca(2+) and K(+) currents in human microglia Neuroscience. 104: 1175-84.  1
2001 Nagai A, Nakagawa E, Hatori K, Choi HB, McLarnon JG, Lee MA, Kim SU. Generation and characterization of immortalized human microglial cell lines: expression of cytokines and chemokines. Neurobiol Dis. 1057-68.  1
2000 McLarnon JG, Helm J, Goghari V, Franciosi S, Choi HB, Nagai A, Kim SU.. Anion channels modulate store-operated calcium influx in human microglia Cell Calcium. 261-8.  1
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