| Year |
Citation |
Score |
| 2023 |
Strassler SE, Bowles IE, Krishnamohan A, Kim H, Edgington CB, Kuiper EG, Hancock CJ, Comstock LR, Jackman JE, Conn GL. tRNA mG9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10. The Journal of Biological Chemistry. 105443. PMID 37949221 DOI: 10.1016/j.jbc.2023.105443 |
0.381 |
|
| 2023 |
Srinivas P, Nosrati M, Zelinskaya N, Dey D, Comstock LR, Dunham CM, Conn GL. 30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. Proceedings of the National Academy of Sciences of the United States of America. 120: e2304128120. PMID 37307464 DOI: 10.1073/pnas.2304128120 |
0.663 |
|
| 2023 |
Parameswaran J, Zhang N, Braems E, Tilahun K, Pant DC, Yin K, Asress S, Heeren K, Banerjee A, Davis E, Schwartz SL, Conn GL, Bassell GJ, Van Den Bosch L, Jiang J. Antisense, but not sense, repeat expanded RNAs activate PKR/eIF2α-dependent ISR in FTD/ALS. Elife. 12. PMID 37073950 DOI: 10.7554/eLife.85902 |
0.338 |
|
| 2023 |
Srinivas P, Nosrati M, Zelinskaya N, Dey D, Comstock LR, Dunham CM, Conn GL. 30S subunit recognition and G1405 modification by the aminoglycoside-resistance 16S ribosomal RNA methyltransferase RmtC. Biorxiv : the Preprint Server For Biology. PMID 36993224 DOI: 10.1101/2023.03.13.532395 |
0.647 |
|
| 2023 |
Strassler SE, Bowles IE, Krishnamohan A, Kim H, Kuiper EG, Comstock LR, Jackman JE, Conn GL. tRNA m G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10. Biorxiv : the Preprint Server For Biology. PMID 36778341 DOI: 10.1101/2023.02.01.526536 |
0.384 |
|
| 2022 |
Strassler SE, Bowles IE, Dey D, Jackman JE, Conn GL. Tied up in knots: Untangling substrate recognition by the SPOUT methyltransferases. The Journal of Biological Chemistry. 102393. PMID 35988649 DOI: 10.1016/j.jbc.2022.102393 |
0.484 |
|
| 2022 |
Laughlin ZT, Nandi S, Dey D, Zelinskaya N, Witek MA, Srinivas P, Nguyen HA, Kuiper EG, Comstock LR, Dunham CM, Conn GL. 50S subunit recognition and modification by the ribosomal RNA methyltransferase TlyA. Proceedings of the National Academy of Sciences of the United States of America. 119: e2120352119. PMID 35357969 DOI: 10.1073/pnas.2120352119 |
0.641 |
|
| 2022 |
Schwartz SL, Dey D, Tanquary J, Bair CR, Lowen AC, Conn GL. Role of helical structure and dynamics in oligoadenylate synthetase 1 (OAS1) mismatch tolerance and activation by short dsRNAs. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35017296 DOI: 10.1073/pnas.2107111119 |
0.427 |
|
| 2021 |
Dey D, Ramakumar S, Conn GL. Targeted Redesign of Suramin Analogs for Novel Antimicrobial Lead Development. Journal of Chemical Information and Modeling. PMID 34516120 DOI: 10.1021/acs.jcim.1c00578 |
0.315 |
|
| 2020 |
Schwartz SL, Park EN, Vachon VK, Danzy S, Lowen AC, Conn GL. Human OAS1 activation is highly dependent on both RNA sequence and context of activating RNA motifs. Nucleic Acids Research. 48: 7520-7531. PMID 32678884 DOI: 10.1093/nar/gkaa513 |
0.433 |
|
| 2019 |
Welty R, Rau M, Pabit S, Dunstan MS, Conn GL, Pollack L, Hall KB. Ribosomal protein L11 selectively stabilizes a tertiary structure of the GTPase Center rRNA domain. Journal of Molecular Biology. PMID 31874150 DOI: 10.1016/j.jmb.2019.12.010 |
0.512 |
|
| 2019 |
Nosrati M, Dey D, Mehrani A, Strassler SE, Zelinskaya N, Hoffer ED, Stagg SM, Dunham CM, Conn GL. Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition. The Journal of Biological Chemistry. PMID 31594862 DOI: 10.1074/Jbc.Ra119.011181 |
0.61 |
|
| 2019 |
Schwartz SL, Conn GL. RNA regulation of the antiviral protein 2'-5'-oligoadenylate synthetase. Wiley Interdisciplinary Reviews. Rna. e1534. PMID 30989826 DOI: 10.1002/wrna.1534 |
0.438 |
|
| 2018 |
Calderon BM, Conn GL. A human cellular noncoding RNA activates the antiviral protein 2'-5'-oligoadenylate synthetase 1. The Journal of Biological Chemistry. PMID 30126839 DOI: 10.1074/jbc.RA118.004747 |
0.412 |
|
| 2017 |
Calderon BM, Conn GL. Human noncoding RNA 886 (nc886) adopts two structurally distinct conformers that are functionally opposing regulators of PKR. Rna (New York, N.Y.). 23: 557-566. PMID 28069888 DOI: 10.1261/rna.060269.116 |
0.488 |
|
| 2017 |
Witek MA, Kuiper EG, Minten E, Crispell EK, Conn GL. A Novel Motif for S-Adenosyl-l-methionine Binding by the Ribosomal RNA Methyltransferase TlyA from Mycobacterium tuberculosis. The Journal of Biological Chemistry. 292: 1977-1987. PMID 28031456 DOI: 10.1074/jbc.M116.752659 |
0.468 |
|
| 2016 |
Fasken MB, Losh JS, Leung SW, Brutus S, Avin B, Vaught JC, Potter-Birriel J, Craig T, Tsanova B, Conn GL, Mills-Lujan K, Corbett AH, van Hoof A. Insight into the RNA Exosome Complex Through Modeling Pontocerebellar Hypoplasia Type 1b Disease Mutations in Yeast. Genetics. PMID 27777260 DOI: 10.1534/Genetics.116.195917 |
0.418 |
|
| 2016 |
Vachon VK, Conn GL. Adenovirus VA RNA: An essential pro-viral non-coding RNA. Virus Research. 212: 39-52. PMID 26116898 DOI: 10.1016/j.virusres.2015.06.018 |
0.444 |
|
| 2016 |
Witek MA, Conn GL. Functional dichotomy in the 16S rRNA (m1A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization Nucleic Acids Research. 44: 342-353. DOI: 10.1093/nar/gkv1306 |
0.311 |
|
| 2015 |
S S, Schwartz SL, Conn GL. The Regulatory and Kinase Domains but not the Interdomain Linker Determine Human Double-Stranded RNA-Activated Kinase (PKR) Sensitivity to Inhibition by Viral Non-coding RNAs. The Journal of Biological Chemistry. PMID 26432638 DOI: 10.1074/jbc.M115.679738 |
0.413 |
|
| 2015 |
Savic M, Sunita S, Zelinskaya N, Desai PM, Macmaster R, Vinal K, Conn GL. 30S Subunit-dependent activation of the Sorangium cellulosum So ce56 aminoglycoside resistance-conferring 16S rRNA methyltransferase Kmr. Antimicrobial Agents and Chemotherapy. 59: 2807-16. PMID 25733511 DOI: 10.1128/AAC.00056-15 |
0.313 |
|
| 2015 |
Vachon VK, Calderon BM, Conn GL. A novel RNA molecular signature for activation of 2'-5' oligoadenylate synthetase-1. Nucleic Acids Research. 43: 544-52. PMID 25477390 DOI: 10.1093/nar/gku1289 |
0.406 |
|
| 2014 |
Kuiper EG, Conn GL. Binding induced RNA conformational changes control substrate recognition and catalysis by the thiostrepton resistance methyltransferase (Tsr). The Journal of Biological Chemistry. 289: 26189-200. PMID 25086036 DOI: 10.1074/jbc.M114.574780 |
0.528 |
|
| 2014 |
Wilson JL, Vachon VK, Sunita S, Schwartz SL, Conn GL. Dissection of the adenoviral VA RNAI central domain structure reveals minimum requirements for RNA-mediated inhibition of PKR. The Journal of Biological Chemistry. 289: 23233-45. PMID 24970889 DOI: 10.1074/jbc.M114.550046 |
0.464 |
|
| 2014 |
Witek MA, Conn GL. Expansion of the aminoglycoside-resistance 16S rRNA (m1A1408) methyltransferase family: Expression and functional characterization of four hypothetical enzymes of diverse bacterial origin Biochimica Et Biophysica Acta - Proteins and Proteomics. 1844: 1648-1655. PMID 24963996 DOI: 10.1016/j.bbapap.2014.06.012 |
0.308 |
|
| 2014 |
Dunkle JA, Vinal K, Desai PM, Zelinskaya N, Savic M, West DM, Conn GL, Dunham CM. Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA. Proceedings of the National Academy of Sciences of the United States of America. 111: 6275-80. PMID 24717845 DOI: 10.1073/Pnas.1402789111 |
0.581 |
|
| 2012 |
Vachon VK, Conn GL. Plasmid template design and in vitro transcription of short RNAs within a "structure cassette" for structure probing experiments. Methods in Molecular Biology (Clifton, N.J.). 941: 157-69. PMID 23065560 DOI: 10.1007/978-1-62703-113-4_12 |
0.496 |
|
| 2012 |
Avis JM, Conn GL, Walker SC. Cis-acting ribozymes for the production of RNA in vitro transcripts with defined 5' and 3' ends. Methods in Molecular Biology (Clifton, N.J.). 941: 83-98. PMID 23065555 DOI: 10.1007/978-1-62703-113-4_7 |
0.368 |
|
| 2012 |
Linpinsel JL, Conn GL. General protocols for preparation of plasmid DNA template, RNA in vitro transcription, and RNA purification by denaturing PAGE. Methods in Molecular Biology (Clifton, N.J.). 941: 43-58. PMID 23065552 DOI: 10.1007/978-1-62703-113-4_4 |
0.478 |
|
| 2011 |
Zelinskaya N, Rankin CR, Macmaster R, Savic M, Conn GL. Expression, purification and crystallization of adenosine 1408 aminoglycoside-resistance rRNA methyltransferases for structural studies. Protein Expression and Purification. 75: 89-94. PMID 20667473 DOI: 10.1016/j.pep.2010.07.005 |
0.333 |
|
| 2011 |
Launer-Felty K, Wong CJ, Wahid AM, Conn GL, Cole JL. Inhibition of PKR by Adenovirus-Associated RNA I Biophysical Journal. 100: 232a-233a. DOI: 10.1016/j.bpj.2010.12.1484 |
0.377 |
|
| 2010 |
Launer-Felty K, Wong CJ, Wahid AM, Conn GL, Cole JL. Magnesium-dependent interaction of PKR with adenovirus VAI. Journal of Molecular Biology. 402: 638-44. PMID 20713064 DOI: 10.1016/j.jmb.2010.08.015 |
0.353 |
|
| 2010 |
Macmaster R, Zelinskaya N, Savic M, Rankin CR, Conn GL. Structural insights into the function of aminoglycoside-resistance A1408 16S rRNA methyltransferases from antibiotic-producing and human pathogenic bacteria. Nucleic Acids Research. 38: 7791-9. PMID 20639535 DOI: 10.1093/nar/gkq627 |
0.347 |
|
| 2010 |
Wong CJ, Heinicke LA, Launer-Felty K, Lary J, Conn GL, Bevilacqua PC, Cole JL. Regulation of PKR By Viral RNAS Biophysical Journal. 98: 13a. DOI: 10.1016/J.Bpj.2009.12.077 |
0.409 |
|
| 2009 |
Wahid AM, Coventry VK, Conn GL. The PKR-binding domain of adenovirus VA RNAI exists as a mixture of two functionally non-equivalent structures. Nucleic Acids Research. 37: 5830-7. PMID 19635730 DOI: 10.1093/nar/gkp595 |
0.487 |
|
| 2009 |
Savic M, Lovric J, Tomic TI, Vasiljevic B, Conn GL. Determination of the target nucleosides for members of two families of 16S rRNA methyltransferases that confer resistance to partially overlapping groups of aminoglycoside antibiotics. Nucleic Acids Research. 37: 5420-31. PMID 19589804 DOI: 10.1093/nar/gkp575 |
0.329 |
|
| 2009 |
Dunstan MS, Hang PC, Zelinskaya NV, Honek JF, Conn GL. Structure of the thiostrepton resistance methyltransferase.S-adenosyl-L-methionine complex and its interaction with ribosomal RNA. The Journal of Biological Chemistry. 284: 17013-20. PMID 19369248 DOI: 10.1074/Jbc.M901618200 |
0.46 |
|
| 2008 |
Savic M, Ilic-Tomic T, Macmaster R, Vasiljevic B, Conn GL. Critical residues for cofactor binding and catalytic activity in the aminoglycoside resistance methyltransferase Sgm. Journal of Bacteriology. 190: 5855-61. PMID 18586937 DOI: 10.1128/JB.00076-08 |
0.338 |
|
| 2008 |
Wahid AM, Coventry VK, Conn GL. Systematic deletion of the adenovirus-associated RNAI terminal stem reveals a surprisingly active RNA inhibitor of double-stranded RNA-activated protein kinase. The Journal of Biological Chemistry. 283: 17485-93. PMID 18430723 DOI: 10.1074/jbc.M802300200 |
0.479 |
|
| 2008 |
Coventry VK, Conn GL. Analysis of adenovirus VA RNAI structure and stability using compensatory base pair modifications. Nucleic Acids Research. 36: 1645-53. PMID 18250084 DOI: 10.1093/nar/gkn020 |
0.507 |
|
| 2008 |
Hobro AJ, Rouhi M, Conn GL, Blanch EW. Raman and Raman optical activity (ROA) analysis of RNA structural motifs Vibrational Spectroscopy. 48: 37-43. DOI: 10.1016/j.vibspec.2007.11.007 |
0.476 |
|
| 2007 |
Dunham CM, Conn GL. Recombinant RNA expression. Nature Methods. 4: 547-8. PMID 17599081 DOI: 10.1038/Nmeth0707-547 |
0.654 |
|
| 2007 |
Hobbs JR, Munger SD, Conn GL. Monellin (MNEI) at 1.15 A resolution. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 162-7. PMID 17329805 DOI: 10.1107/S1744309107005271 |
0.351 |
|
| 2007 |
Hobro AJ, Rouhi M, Blanch EW, Conn GL. Raman and Raman optical activity (ROA) analysis of RNA structural motifs in Domain I of the EMCV IRES Nucleic Acids Research. 35: 1169-1177. PMID 17264119 DOI: 10.1093/nar/gkm012 |
0.415 |
|
| 2006 |
Maeder C, Conn GL, Draper DE. Optimization of a ribosomal structural domain by natural selection. Biochemistry. 45: 6635-43. PMID 16716074 DOI: 10.1021/Bi052544P |
0.682 |
|
| 2005 |
Dunstan MS, Guhathakurta D, Draper DE, Conn GL. Coevolution of protein and RNA structures within a highly conserved ribosomal domain. Chemistry & Biology. 12: 201-6. PMID 15734647 DOI: 10.1016/J.Chembiol.2004.11.019 |
0.723 |
|
| 2004 |
Phelan M, Banks RJ, Conn G, Ramesh V. NMR studies of the structure and Mg2+ binding properties of a conserved RNA motif of EMCV picornavirus IRES element. Nucleic Acids Research. 32: 4715-24. PMID 15353559 DOI: 10.1093/Nar/Gkh805 |
0.513 |
|
| 2003 |
Clark AT, Robertson MEM, Conn GL, Belsham GJ. Conserved Nucleotides within the J Domain of the Encephalomyocarditis Virus Internal Ribosome Entry Site Are Required for Activity and for Interaction with eIF4G Journal of Virology. 77: 12441-12449. PMID 14610168 DOI: 10.1128/JVI.77.23.12441-12449.2003 |
0.351 |
|
| 2003 |
Conn GL. Expression of active RNA-activated protein kinase (PKR) in bacteria. Biotechniques. 35: 682-4, 686. PMID 14579730 |
0.308 |
|
| 2003 |
Walker SC, Avis JM, Conn GL. General plasmids for producing RNA in vitro transcripts with homogeneous ends. Nucleic Acids Research. 31: e82. PMID 12888534 |
0.412 |
|
| 2003 |
Gyi JI, Gao D, Conn GL, Trent JO, Brown T, Lane AN. The solution structure of a DNA*RNA duplex containing 5-propynyl U and C; comparison with 5-Me modifications. Nucleic Acids Research. 31: 2683-93. PMID 12736318 DOI: 10.1093/Nar/Gkg356 |
0.52 |
|
| 2002 |
Conn GL, Gittis AG, Lattman EE, Misra VK, Draper DE. A compact RNA tertiary structure contains a buried backbone-K+ complex. Journal of Molecular Biology. 318: 963-73. PMID 12054794 DOI: 10.1016/S0022-2836(02)00147-X |
0.633 |
|
| 1999 |
Conn GL, Draper DE, Lattman EE, Gittis AG. Crystal structure of a conserved ribosomal protein-RNA complex. Science (New York, N.Y.). 284: 1171-4. PMID 10325228 DOI: 10.1126/Science.284.5417.1171 |
0.704 |
|
| 1999 |
Conn GL, Brown T, Leonard GA. The crystal structure of the RNA/DNA hybrid r(GAAGAGAAGC). d(GCTTCTCTTC) shows significant differences to that found in solution. Nucleic Acids Research. 27: 555-61. PMID 9862980 DOI: 10.1093/Nar/27.2.555 |
0.6 |
|
| 1998 |
Conn GL, Gutell RR, Draper DE. A functional ribosomal RNA tertiary structure involves a base triple interaction. Biochemistry. 37: 11980-8. PMID 9718323 DOI: 10.1021/Bi980825+ |
0.698 |
|
| 1998 |
Conn GL, Draper DE. RNA structure. Current Opinion in Structural Biology. 8: 278-85. PMID 9666322 DOI: 10.1016/S0959-440X(98)80059-6 |
0.68 |
|
| 1998 |
Gyi JI, Lane AN, Conn GL, Brown T. The orientation and dynamics of the C2'-OH and hydration of RNA and DNA.RNA hybrids. Nucleic Acids Research. 26: 3104-10. PMID 9628906 DOI: 10.1093/Nar/26.13.3104 |
0.588 |
|
| 1998 |
Gyi JI, Lane AN, Conn GL, Brown T. Solution structures of DNA.RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DNA and RNA duplexes. Biochemistry. 37: 73-80. PMID 9425027 DOI: 10.1021/Bi9719713 |
0.491 |
|
| 1997 |
Bonifacio GF, Brown T, Conn GL, Lane AN. Comparison of the electrophoretic and hydrodynamic properties of DNA and RNA oligonucleotide duplexes. Biophysical Journal. 73: 1532-8. PMID 9284320 DOI: 10.1016/S0006-3495(97)78185-2 |
0.564 |
|
| 1997 |
Conte MR, Conn GL, Brown T, Lane AN. Conformational properties and thermodynamics of the RNA duplex r(CGCAAAUUUGCG)2: comparison with the DNA analogue d(CGCAAATTTGCG)2. Nucleic Acids Research. 25: 2627-34. PMID 9185574 DOI: 10.1093/Nar/25.13.2627 |
0.536 |
|
| 1997 |
Sutton DH, Conn GL, Brown T, Lane AN. The dependence of DNase I activity on the conformation of oligodeoxynucleotides. The Biochemical Journal. 481-6. PMID 9020884 DOI: 10.1042/Bj3210481 |
0.531 |
|
| 1996 |
Conte MR, Conn GL, Brown T, Lane AN. Hydration of the RNA duplex r(CGCAAAUUUGCG)2 determined by NMR. Nucleic Acids Research. 24: 3693-9. PMID 8871546 DOI: 10.1093/Nar/24.19.3693 |
0.511 |
|
| 1996 |
Gyi JI, Conn GL, Lane AN, Brown T. Comparison of the thermodynamic stabilities and solution conformations of DNA.RNA hybrids containing purine-rich and pyrimidine-rich strands with DNA and RNA duplexes. Biochemistry. 35: 12538-48. PMID 8823191 DOI: 10.1021/Bi960948Z |
0.564 |
|
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