Michelle L. Block - Publications

Affiliations: 
Virginia Commonwealth University, Richmond, VA, United States 
 Indiana University School of Medicine, Indianapolis, IN, United States 
Area:
Microglia Biology
Website:
http://snri.medicine.iu.edu/people/primary-investigators/michelle-l-block-ph-d/

52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Taetzsch T, Benusa S, Levesque S, Mumaw CL, Block ML. Loss of NF-κB p50 function synergistically augments microglial priming in the middle-aged brain. Journal of Neuroinflammation. 16: 60. PMID 30871598 DOI: 10.1186/s12974-019-1446-z  0.6
2016 Mumaw CL, Surace M, Levesque S, Kodavanti UP, Kodavanti PR, Royland JE, Block ML. Atypical Microglial Response to Biodiesel Exhaust in Healthy and Hypertensive Rats. Neurotoxicology. PMID 27777102 DOI: 10.1016/j.neuro.2016.10.012  0.6
2016 Mumaw CL, Levesque S, McGraw C, Robertson S, Lucas S, Stafflinger JE, Campen MJ, Hall P, Norenberg JP, Anderson T, Lund AK, McDonald JD, Ottens AK, Block ML. Microglial priming through the lung-brain axis: the role of air pollution-induced circulating factors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26864854 DOI: 10.1096/fj.201500047  0.92
2015 Baig MS, Zaichick SV, Mao M, de Abreu AL, Bakhshi FR, Hart PC, Saqib U, Deng J, Chatterjee S, Block ML, Vogel SM, Malik AB, Consolaro ME, Christman JW, Minshall RD, et al. NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1. The Journal of Experimental Medicine. PMID 26324446 DOI: 10.1084/jem.20140654  0.92
2015 Taetzsch T, Levesque S, McGraw C, Brookins S, Luqa R, Bonini MG, Mason RP, Oh U, Block ML. Redox regulation of NF-κB p50 and M1 polarization in microglia. Glia. 63: 423-40. PMID 25331559 DOI: 10.1002/glia.22762  0.92
2014 Biber K, Block ML. Neuroprotection versus neurotoxicity Microglia in Health and Disease. 145-172. DOI: 10.1007/978-1-4939-1429-6_6  0.92
2013 Dallas S, Block ML, Thompson DM, Bonini MG, Ronaldson PT, Bendayan R, Miller DS. Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment. Journal of Neuroinflammation. 10: 58. PMID 23642074 DOI: 10.1186/1742-2094-10-58  0.6
2013 Levesque S, Taetzsch T, Lull ME, Johnson JA, McGraw C, Block ML. The role of MAC1 in diesel exhaust particle-induced microglial activation and loss of dopaminergic neuron function. Journal of Neurochemistry. 125: 756-65. PMID 23470120 DOI: 10.1111/jnc.12231  0.6
2013 Taetzsch T, Block ML. Pesticides, microglial NOX2, and Parkinson's disease. Journal of Biochemical and Molecular Toxicology. 27: 137-49. PMID 23349115 DOI: 10.1002/jbt.21464  0.6
2012 Block ML, Elder A, Auten RL, Bilbo SD, Chen H, Chen JC, Cory-Slechta DA, Costa D, Diaz-Sanchez D, Dorman DC, Gold DR, Gray K, Jeng HA, Kaufman JD, Kleinman MT, et al. The outdoor air pollution and brain health workshop. Neurotoxicology. 33: 972-84. PMID 22981845 DOI: 10.1016/j.neuro.2012.08.014  0.6
2011 Levesque S, Surace MJ, McDonald J, Block ML. Air pollution & the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease. Journal of Neuroinflammation. 8: 105. PMID 21864400 DOI: 10.1186/1742-2094-8-105  0.6
2011 Lull ME, Levesque S, Surace MJ, Block ML. Chronic apocynin treatment attenuates beta amyloid plaque size and microglial number in hAPP(751)(SL) mice. Plos One. 6: e20153. PMID 21655287 DOI: 10.1371/journal.pone.0020153  0.6
2011 Levesque S, Taetzsch T, Lull ME, Kodavanti U, Stadler K, Wagner A, Johnson JA, Duke L, Kodavanti P, Surace MJ, Block ML. Diesel exhaust activates and primes microglia: air pollution, neuroinflammation, and regulation of dopaminergic neurotoxicity. Environmental Health Perspectives. 119: 1149-55. PMID 21561831 DOI: 10.1289/ehp.1002986  0.6
2010 Lull ME, Block ML. Microglial activation and chronic neurodegeneration. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 7: 354-65. PMID 20880500 DOI: 10.1016/j.nurt.2010.05.014  0.6
2010 Luo L, Rodriguez E, Jerbi K, Lachaux JP, Martinerie J, Corbetta M, Shulman GL, Piomelli D, Turrigiano GG, Nelson SB, Joëls M, de Kloet ER, Holsboer F, Amodio DM, Frith CD, ... Block ML, et al. Ten years of Nature Reviews Neuroscience: insights from the highly cited. Nature Reviews. Neuroscience. 11: 718-26. PMID 20852655 DOI: 10.1038/nrn2912  0.6
2010 Hahn YK, Vo P, Fitting S, Block ML, Hauser KF, Knapp PE. beta-Chemokine production by neural and glial progenitor cells is enhanced by HIV-1 Tat: effects on microglial migration. Journal of Neurochemistry. 114: 97-109. PMID 20403075 DOI: 10.1111/j.1471-4159.2010.06744.x  0.6
2010 Levesque S, Wilson B, Gregoria V, Thorpe LB, Dallas S, Polikov VS, Hong JS, Block ML. Reactive microgliosis: extracellular micro-calpain and microglia-mediated dopaminergic neurotoxicity. Brain : a Journal of Neurology. 133: 808-21. PMID 20123724 DOI: 10.1093/brain/awp333  0.6
2009 Block ML, Calderón-Garcidueñas L. Air pollution: mechanisms of neuroinflammation and CNS disease. Trends in Neurosciences. 32: 506-16. PMID 19716187 DOI: 10.1016/j.tins.2009.05.009  0.92
2008 Block ML. NADPH oxidase as a therapeutic target in Alzheimer's disease. Bmc Neuroscience. 9: S8. PMID 19090996 DOI: 10.1186/1471-2202-9-S2-S8  0.92
2008 Ding Y, Qiao A, Wang Z, Goodwin JS, Lee ES, Block ML, Allsbrook M, McDonald MP, Fan GH. Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11622-34. PMID 18987198 DOI: 10.1523/JNEUROSCI.3153-08.2008  0.92
2008 Hu X, Zhang D, Pang H, Caudle WM, Li Y, Gao H, Liu Y, Qian L, Wilson B, Di Monte DA, Ali SF, Zhang J, Block ML, Hong JS. Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease. Journal of Immunology (Baltimore, Md. : 1950). 181: 7194-204. PMID 18981141  0.6
2008 Wu X, Chen PS, Dallas S, Wilson B, Block ML, Wang CC, Kinyamu H, Lu N, Gao X, Leng Y, Chuang DM, Zhang W, Lu RB, Hong JS. Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 11: 1123-34. PMID 18611290 DOI: 10.1017/S1461145708009024  0.92
2008 Hartz AM, Bauer B, Block ML, Hong JS, Miller DS. Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2723-33. PMID 18474546 DOI: 10.1096/fj.08-106997  0.92
2008 Gao X, Hu X, Qian L, Yang S, Zhang W, Zhang D, Wu X, Fraser A, Wilson B, Flood PM, Block M, Hong JS. Formyl-methionyl-leucyl-phenylalanine-induced dopaminergic neurotoxicity via microglial activation: a mediator between peripheral infection and neurodegeneration? Environmental Health Perspectives. 116: 593-8. PMID 18470306 DOI: 10.1289/ehp.11031  0.92
2008 Yang S, Zhang D, Yang Z, Hu X, Qian S, Liu J, Wilson B, Block M, Hong JS. Curcumin protects dopaminergic neuron against LPS induced neurotoxicity in primary rat neuron/glia culture. Neurochemical Research. 33: 2044-53. PMID 18368483 DOI: 10.1007/s11064-008-9675-z  0.92
2008 MohanKumar SMJ, Campbell A, Block M, Veronesi B. Particulate matter, oxidative stress and neurotoxicity Neurotoxicology. 29: 478-487. DOI: 10.1016/j.neuro.2007.12.004  0.92
2007 Qian L, Gao X, Pei Z, Wu X, Block M, Wilson B, Hong JS, Flood PM. NADPH oxidase inhibitor DPI is neuroprotective at femtomolar concentrations through inhibition of microglia over-activation. Parkinsonism & Related Disorders. 13: S316-20. PMID 18267257 DOI: 10.1016/S1353-8020(08)70023-3  0.92
2007 Block ML, Hong JS. Chronic microglial activation and progressive dopaminergic neurotoxicity. Biochemical Society Transactions. 35: 1127-32. PMID 17956294 DOI: 10.1042/BST0351127  0.92
2007 Pei Z, Pang H, Qian L, Yang S, Wang T, Zhang W, Wu X, Dallas S, Wilson B, Reece JM, Miller DS, Hong JS, Block ML. MAC1 mediates LPS-induced production of superoxide by microglia: the role of pattern recognition receptors in dopaminergic neurotoxicity. Glia. 55: 1362-73. PMID 17654704 DOI: 10.1002/glia.20545  0.92
2007 Qin L, Wu X, Block ML, Liu Y, Breese GR, Hong JS, Knapp DJ, Crews FT. Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration. Glia. 55: 453-62. PMID 17203472 DOI: 10.1002/glia.20467  0.92
2007 Block ML, Zecca L, Hong JS. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nature Reviews. Neuroscience. 8: 57-69. PMID 17180163 DOI: 10.1038/nrn2038  0.92
2007 Kim YS, Choi DH, Block ML, Lorenzl S, Yang L, Kim YJ, Sugama S, Cho BP, Hwang O, Browne SE, Kim SY, Hong JS, Beal MF, Joh TH. A pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 179-87. PMID 17116747 DOI: 10.1096/fj.06-5865com  0.92
2006 Yang S, Yang J, Yang Z, Chen P, Fraser A, Zhang W, Pang H, Gao X, Wilson B, Hong JS, Block ML. Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 and PACAP4-6 are neuroprotective through inhibition of NADPH oxidase: potent regulators of microglia-mediated oxidative stress. The Journal of Pharmacology and Experimental Therapeutics. 319: 595-603. PMID 16891616 DOI: 10.1124/jpet.106.102236  0.92
2006 Polikov VS, Block ML, Fellous JM, Hong JS, Reichert WM. In vitro model of glial scarring around neuroelectrodes chronically implanted in the CNS. Biomaterials. 27: 5368-76. PMID 16842846 DOI: 10.1016/j.biomaterials.2006.06.018  0.92
2006 Qian L, Block ML, Wei SJ, Lin CF, Reece J, Pang H, Wilson B, Hong JS, Flood PM. Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase. The Journal of Pharmacology and Experimental Therapeutics. 319: 44-52. PMID 16807359 DOI: 10.1124/jpet.106.106351  0.92
2006 Wang T, Zhang W, Pei Z, Block M, Wilson B, Reece JM, Miller DS, Hong JS. Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 906-15. PMID 16675848 DOI: 10.1096/fj.05-5053com  0.92
2006 Block ML, Li G, Qin L, Wu X, Pei Z, Wang T, Wilson B, Yang J, Hong JS. Potent regulation of microglia-derived oxidative stress and dopaminergic neuron survival: substance P vs. dynorphin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 251-8. PMID 16449797 DOI: 10.1096/fj.05-4553com  0.92
2005 Qin L, Liu Y, Qian X, Hong JS, Block ML. Microglial NADPH oxidase mediates leucine enkephalin dopaminergic neuroprotection. Annals of the New York Academy of Sciences. 1053: 107-20. PMID 16179514 DOI: 10.1196/annals.1344.009  0.92
2005 He YY, Huang JL, Block ML, Hong JS, Chignell CF. Role of phagocyte oxidase in UVA-induced oxidative stress and apoptosis in keratinocytes. The Journal of Investigative Dermatology. 125: 560-6. PMID 16117799 DOI: 10.1111/j.0022-202X.2005.23851.x  0.92
2005 Block ML, Hong JS. Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Progress in Neurobiology. 76: 77-98. PMID 16081203 DOI: 10.1016/j.pneurobio.2005.06.004  0.92
2005 Qin L, Li G, Qian X, Liu Y, Wu X, Liu B, Hong JS, Block ML. Interactive role of the toll-like receptor 4 and reactive oxygen species in LPS-induced microglia activation. Glia. 52: 78-84. PMID 15920727 DOI: 10.1002/glia.20225  0.92
2005 Wu XF, Block ML, Zhang W, Qin L, Wilson B, Zhang WQ, Veronesi B, Hong JS. The role of microglia in paraquat-induced dopaminergic neurotoxicity. Antioxidants & Redox Signaling. 7: 654-61. PMID 15890010 DOI: 10.1089/ars.2005.7.654  0.92
2005 Qin L, Block ML, Liu Y, Bienstock RJ, Pei Z, Zhang W, Wu X, Wilson B, Burka T, Hong JS. Microglial NADPH oxidase is a novel target for femtomolar neuroprotection against oxidative stress. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 550-7. PMID 15791005 DOI: 10.1096/fj.04-2857com  0.92
2005 Zhang W, Wang T, Pei Z, Miller DS, Wu X, Block ML, Wilson B, Zhang W, Zhou Y, Hong JS, Zhang J. Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 533-42. PMID 15791003 DOI: 10.1096/fj.04-2751com  0.92
2005 Li G, Cui G, Tzeng NS, Wei SJ, Wang T, Block ML, Hong JS. Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 489-96. PMID 15790998 DOI: 10.1096/fj.04-2555com  0.92
2005 Li G, Liu Y, Tzeng NS, Cui G, Block ML, Wilson B, Qin L, Wang T, Liu B, Liu J, Hong JS. Protective effect of dextromethorphan against endotoxic shock in mice. Biochemical Pharmacology. 69: 233-40. PMID 15627475 DOI: 10.1016/j.bcp.2004.10.003  0.92
2004 Zhang W, Hong JS, Kim HC, Zhang W, Block ML. Morphinan neuroprotection: new insight into the therapy of neurodegeneration. Critical Reviews in Neurobiology. 16: 271-302. PMID 15862109 DOI: 10.1615/CritRevNeurobiol.v16.i4.30  0.92
2004 Block ML, Wu X, Pei Z, Li G, Wang T, Qin L, Wilson B, Yang J, Hong JS, Veronesi B. Nanometer size diesel exhaust particles are selectively toxic to dopaminergic neurons: the role of microglia, phagocytosis, and NADPH oxidase. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1618-20. PMID 15319363 DOI: 10.1096/fj.04-1945fje  0.92
2004 Qin L, Liu Y, Wang T, Wei SJ, Block ML, Wilson B, Liu B, Hong JS. NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia. The Journal of Biological Chemistry. 279: 1415-21. PMID 14578353 DOI: 10.1074/jbc.M307657200  0.92
1997 Granger DA, Hood KE, Ikeda SC, Reed CL, Jones BC, Block ML. Effects of peripheral immune activation on social behavior and adrenocortical activity in aggressive mice: Genotype-environment interactions Aggressive Behavior. 23: 93-105.  0.92
1996 Granger DA, Hood KE, Ikeda SC, Reed CL, Block ML. Neonatal endotoxin exposure alters the development of social behavior and the hypothalamic-pituitary-adrenal axis in selectively bred mice. Brain, Behavior, and Immunity. 10: 249-59. PMID 8954597 DOI: 10.1006/brbi.1996.0022  0.92
1981 Block ML, Volpe LC, Hayes MJ. Saliva as a chemical cue in the development of social behavior. Science (New York, N.Y.). 211: 1062-4. PMID 7466378  0.92
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