Mark Yeager - Publications

Molecular Physiology and Biological Physics University of Virginia, Charlottesville, VA 

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Khan AK, Jagielnicki M, McIntire WE, Purdy MD, Dharmarajan V, Griffin PR, Yeager M. A Steric "Ball-and-Chain" Mechanism for pH-Mediated Regulation of Gap Junction Channels. Cell Reports. 31: 107482. PMID 32320665 DOI: 10.1016/j.celrep.2020.03.046  0.36
2020 Mukherjee S, Erramilli SK, Ammirati M, Alvarez FJD, Fennell KF, Purdy MD, Skrobek BM, Radziwon K, Coukos J, Kang Y, Dutka P, Gao X, Qiu X, Yeager M, Eric Xu H, et al. Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins. Nature Communications. 11: 1598. PMID 32221310 DOI: 10.1038/s41467-020-15363-0  0.36
2019 Han H, Schubert HL, McCullough J, Monroe N, Purdy MD, Yeager M, Sundquist WI, Hill CP. Structure of spastin bound to a glutamate-rich peptide implies a hand-over-hand mechanism of substrate translocation. The Journal of Biological Chemistry. PMID 31767681 DOI: 10.1074/jbc.AC119.009890  0.36
2019 Marques MA, Purdy MD, Yeager M. CryoEM maps are full of potential. Current Opinion in Structural Biology. PMID 31400843 DOI: 10.1016/  0.36
2018 Purdy MD, Shi D, Chrustowicz J, Hattne J, Gonen T, Yeager M. MicroED structures of HIV-1 Gag CTD-SP1 reveal binding interactions with the maturation inhibitor bevirimat. Proceedings of the National Academy of Sciences of the United States of America. PMID 30530702 DOI: 10.1073/pnas.1806806115  0.36
2016 Wagner JM, Zadrozny KK, Chrustowicz J, Purdy MD, Yeager M, Ganser-Pornillos BK, Pornillos O. Crystal structure of an HIV assembly and maturation switch. Elife. 5. PMID 27416583 DOI: 10.7554/eLife.17063  0.36
2016 Grime JM, Dama JF, Ganser-Pornillos BK, Woodward CL, Jensen GJ, Yeager M, Voth GA. Coarse-grained simulation reveals key features of HIV-1 capsid self-assembly. Nature Communications. 7: 11568. PMID 27174390 DOI: 10.1038/ncomms11568  0.48
2016 Bennett BC, Purdy MD, Baker KA, Acharya C, McIntire WE, Stevens RC, Zhang Q, Harris AL, Abagyan R, Yeager M. An electrostatic mechanism for Ca(2+)-mediated regulation of gap junction channels. Nature Communications. 7: 8770. PMID 26753910 DOI: 10.1038/ncomms9770  0.48
2014 Bhattacharya A, Alam SL, Fricke T, Zadrozny K, Sedzicki J, Taylor AB, Demeler B, Pornillos O, Ganser-Pornillos BK, Diaz-Griffero F, Ivanov DN, Yeager M. Structural basis of HIV-1 capsid recognition by PF74 and CPSF6. Proceedings of the National Academy of Sciences of the United States of America. 111: 18625-30. PMID 25518861 DOI: 10.1073/pnas.1419945112  0.48
2014 Purdy MD, Bennett BC, McIntire WE, Khan AK, Kasson PM, Yeager M. Function and dynamics of macromolecular complexes explored by integrative structural and computational biology. Current Opinion in Structural Biology. 27: 138-48. PMID 25238653 DOI: 10.1016/  0.48
2014 Kennedy DP, McRobb FM, Leonhardt SA, Purdy M, Figler H, Marshall MA, Chordia M, Figler R, Linden J, Abagyan R, Yeager M. The second extracellular loop of the adenosine A1 receptor mediates activity of allosteric enhancers. Molecular Pharmacology. 85: 301-9. PMID 24217444 DOI: 10.1124/mol.113.088682  0.48
2013 Lee SC, Bennett BC, Hong WX, Fu Y, Baker KA, Marcoux J, Robinson CV, Ward AB, Halpert JR, Stevens RC, Stout CD, Yeager MJ, Zhang Q. Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins. Proceedings of the National Academy of Sciences of the United States of America. 110: E1203-11. PMID 23479627 DOI: 10.1073/pnas.1221442110  0.48
2012 Ganser-Pornillos BK, Yeager M, Pornillos O. Assembly and architecture of HIV. Advances in Experimental Medicine and Biology. 726: 441-65. PMID 22297526 DOI: 10.1007/978-1-4614-0980-9_20  0.48
2011 Pornillos O, Ganser-Pornillos BK, Yeager M. Atomic-level modelling of the HIV capsid. Nature. 469: 424-7. PMID 21248851 DOI: 10.1038/nature09640  0.48
2011 Bigler Wang D, Sherman NE, Shannon JD, Leonhardt SA, Mayeenuddin LH, Yeager M, McIntire WE. Binding of β4γ5 by adenosine A1 and A2A receptors determined by stable isotope labeling with amino acids in cell culture and mass spectrometry Biochemistry. 50: 207-220. PMID 21128647 DOI: 10.1021/bi101227y  0.48
2010 Gastaminza P, Dryden KA, Boyd B, Wood MR, Law M, Yeager M, Chisari FV. Ultrastructural and biophysical characterization of hepatitis C virus particles produced in cell culture. Journal of Virology. 84: 10999-1009. PMID 20686033 DOI: 10.1128/JVI.00526-10  0.48
2010 Pornillos O, Ganser-Pornillos BK, Banumathi S, Hua Y, Yeager M. Disulfide bond stabilization of the hexameric capsomer of human immunodeficiency virus. Journal of Molecular Biology. 401: 985-95. PMID 20600115 DOI: 10.1016/j.jmb.2010.06.042  0.48
2010 Hong WX, Baker KA, Ma X, Stevens RC, Yeager M, Zhang Q. Design, synthesis, and properties of branch-chained maltoside detergents for stabilization and crystallization of integral membrane proteins: human connexin 26. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 8690-6. PMID 20232919 DOI: 10.1021/la904893d  0.48
2010 Katritch V, Jaakola VP, Lane JR, Lin J, Ijzerman AP, Yeager M, Kufareva I, Stevens RC, Abagyan R. Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists. Journal of Medicinal Chemistry. 53: 1799-809. PMID 20095623 DOI: 10.1021/jm901647p  0.48
2009 Dryden KA, Crowley CS, Tanaka S, Yeates TO, Yeager M. Two-dimensional crystals of carboxysome shell proteins recapitulate the hexagonal packing of three-dimensional crystals. Protein Science : a Publication of the Protein Society. 18: 2629-35. PMID 19844993 DOI: 10.1002/pro.272  0.48
2009 Tang J, Lee KK, Bothner B, Baker TS, Yeager M, Johnson JE. Dynamics and stability in maturation of a T=4 virus. Journal of Molecular Biology. 392: 803-12. PMID 19627990 DOI: 10.1016/j.jmb.2009.07.038  0.48
2009 Pornillos O, Ganser-Pornillos BK, Kelly BN, Hua Y, Whitby FG, Stout CD, Sundquist WI, Hill CP, Yeager M. X-ray structures of the hexameric building block of the HIV capsid. Cell. 137: 1282-92. PMID 19523676 DOI: 10.1016/j.cell.2009.04.063  0.48
2009 Katritch V, Reynolds KA, Cherezov V, Hanson MA, Roth CB, Yeager M, Abagyan R. Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes. Journal of Molecular Recognition : Jmr. 22: 307-18. PMID 19353579 DOI: 10.1002/jmr.949  0.48
2008 Kovacs JA, Yeager M, Abagyan R. Damped-dynamics flexible fitting. Biophysical Journal. 95: 3192-207. PMID 18586844 DOI: 10.1529/biophysj.108.132357  0.48
2008 Ganser-Pornillos BK, Yeager M, Sundquist WI. The structural biology of HIV assembly. Current Opinion in Structural Biology. 18: 203-17. PMID 18406133 DOI: 10.1016/  0.48
2007 Yeager M, Harris AL. Gap junction channel structure in the early 21st century: facts and fantasies. Current Opinion in Cell Biology. 19: 521-8. PMID 17945477 DOI: 10.1016/  0.48
2007 Manayani DJ, Thomas D, Dryden KA, Reddy V, Siladi ME, Marlett JM, Rainey GJ, Pique ME, Scobie HM, Yeager M, Young JA, Manchester M, Schneemann A. A viral nanoparticle with dual function as an anthrax antitoxin and vaccine. Plos Pathogens. 3: 1422-31. PMID 17922572 DOI: 10.1371/journal.ppat.0030142  0.48
2007 Hanson MA, Brooun A, Baker KA, Jaakola VP, Roth C, Chien EY, Alexandrov A, Velasquez J, Davis L, Griffith M, Moy K, Ganser-Pornillos BK, Hua Y, Kuhn P, Ellis S, ... Yeager M, et al. Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression. Protein Expression and Purification. 56: 85-92. PMID 17723307 DOI: 10.1016/j.pep.2007.06.003  0.48
2007 Kovacs JA, Baker KA, Altenberg GA, Abagyan R, Yeager M. Molecular modeling and mutagenesis of gap junction channels. Progress in Biophysics and Molecular Biology. 94: 15-28. PMID 17524457 DOI: 10.1016/j.pbiomolbio.2007.03.013  0.48
2007 Kovacs JA, Yeager M, Abagyan R. Computational prediction of atomic structures of helical membrane proteins aided by EM maps. Biophysical Journal. 93: 1950-9. PMID 17496035 DOI: 10.1529/biophysj.106.102137  0.48
2007 Ren G, Gao K, Bushman FD, Yeager M. Single-particle Image Reconstruction of a Tetramer of HIV Integrase Bound to DNA Journal of Molecular Biology. 366: 286-294. PMID 17157316 DOI: 10.1016/j.jmb.2006.11.029  0.48
2006 Craig L, Volkmann N, Arvai AS, Pique ME, Yeager M, Egelman EH, Tainer JA. Type IV pilus structure by cryo-electron microscopy and crystallography: implications for pilus assembly and functions. Molecular Cell. 23: 651-62. PMID 16949362 DOI: 10.1016/j.molcel.2006.07.004  0.48
2006 Dryden KA, Wieland SF, Whitten-Bauer C, Gerin JL, Chisari FV, Yeager M. Native hepatitis B virions and capsids visualized by electron cryomicroscopy. Molecular Cell. 22: 843-50. PMID 16793552 DOI: 10.1016/j.molcel.2006.04.025  0.48
2006 Daniels MJ, Wood MR, Yeager M. In vivo functional assay of a recombinant aquaporin in Pichia pastoris Applied and Environmental Microbiology. 72: 1507-1514. PMID 16461705 DOI: 10.1128/AEM.72.2.1507-1514.2006  0.48
2005 Adair BD, Xiong JP, Maddock C, Goodman SL, Arnaout MA, Yeager M. Three-dimensional EM structure of the ectodomain of integrin αVβ3 in a complex with fibronectin Journal of Cell Biology. 168: 1109-1118. PMID 15795319 DOI: 10.1083/jcb.200410068  0.48
2004 Becker CF, Strop P, Bass RB, Hansen KC, Locher KP, Ren G, Yeager M, Rees DC, Kochendoerfer GG. Conversion of a mechanosensitive channel protein from a membrane-embedded to a water-soluble form by covalent modification with amphiphiles. Journal of Molecular Biology. 343: 747-58. PMID 15465059 DOI: 10.1016/j.jmb.2004.08.062  0.48
2004 Fleishman SJ, Unger VM, Yeager M, Ben-Tal N. A Calpha model for the transmembrane alpha helices of gap junction intercellular channels. Molecular Cell. 15: 879-88. PMID 15383278 DOI: 10.1016/j.molcel.2004.08.016  0.48
2004 Brill LM, Dechongkit S, DeLaBarre B, Stroebel J, Beachy RN, Yeager M. Dimerization of recombinant tobacco mosaic virus movement protein. Journal of Virology. 78: 3372-7. PMID 15016859 DOI: 10.1128/JVI.78.5.3372-3377.2004  0.48
2004 Tihova M, Dryden KA, Le TV, Harvey SC, Johnson JE, Yeager M, Schneemann A. Nodavirus coat protein imposes dodecahedral RNA structure independent of nucleotide sequence and length. Journal of Virology. 78: 2897-905. PMID 14990708 DOI: 10.1128/JVI.78.6.2897-2905.2004  0.48
2004 Granville DJ, Tashakkor B, Takeuchi C, Gustafsson AB, Huang C, Sayen MR, Wentworth P, Yeager M, Gottlieb RA. Reduction of ischemia and reperfusion-induced myocardial damage by cytochrome P450 inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 101: 1321-6. PMID 14734800 DOI: 10.1073/pnas.0308185100  0.48
2003 Ganser BK, Cheng A, Sundquist WI, Yeager M. Three-dimensional structure of the M-MuLV CA protein on a lipid monolayer: a general model for retroviral capsid assembly. The Embo Journal. 22: 2886-92. PMID 12805204 DOI: 10.1093/emboj/cdg276  0.48
2003 Craig L, Taylor RK, Pique ME, Adair BD, Arvai AS, Singh M, Lloyd SJ, Shin DS, Getzoff ED, Yeager M, Forest KT, Tainer JA. Type IV pilin structure and assembly: X-ray and EM analyses of Vibrio cholerae toxin-coregulated pilus and Pseudomonas aeruginosa PAK pilin. Molecular Cell. 11: 1139-50. PMID 12769840 DOI: 10.1016/S1097-2765(03)00170-9  0.48
2002 Tang L, Lin CS, Krishna NK, Yeager M, Schneemann A, Johnson JE. Virus-like particles of a fish nodavirus display a capsid subunit domain organization different from that of insect nodaviruses Journal of Virology. 76: 6370-6375. PMID 12021370 DOI: 10.1128/JVI.76.12.6370-6375.2002  0.48
2001 Tihova M, Dryden KA, Bellamy AR, Greenberg HB, Yeager M. Localization of membrane permeabilization and receptor binding sites on the VP4 hemagglutinin of rotavirus: Implications for cell entry Journal of Molecular Biology. 314: 985-992. PMID 11743716 DOI: 10.1006/jmbi.2000.5238  0.48
2001 Yeager M, Unger VM. Culturing of mammalian cells expressing recombinant connexins and two-dimensional crystallization of the isolated gap junctions Methods in Molecular Biology (Clifton, N.J.). 154: 77-89. PMID 11218666 DOI: 10.1385/1-59259-043-8:77  0.48
2001 Tang L, Johnson KN, Ball LA, Lin T, Yeager M, Johnson JE. The structure of pariacoto virus reveals a dodecahedral cage of duplex RNA. Nature Structural Biology. 8: 77-83. PMID 11135676 DOI: 10.1038/83089  0.48
1999 Unger VM, Kumar NM, Gilula NB, Yeager M. Expression, two-dimensional crystallization, and electron cryo- crystallography of recombinant gap junction membrane channels Journal of Structural Biology. 128: 98-105. PMID 10600564 DOI: 10.1006/jsbi.1999.4184  0.48
1999 Unger VM, Kumar NM, Gilula NB, Yeager M. Electron cryo-crystallography of a recombinant cardiac gap junction channel Novartis Foundation Symposium. 219: 22-37. PMID 10207896 DOI: 10.1002/9780470515587.CH3  0.48
1999 Unger VM, Kumar NM, Gilula NB, Yeager M. Three-dimensional structure of a recombinant gap junction membrane channel Science. 283: 1176-1180. PMID 10024245 DOI: 10.1126/science.283.5405.1176  0.48
1998 Yeager M, Unger VM, Mitra AK. Three-dimensional structure of membrane proteins determined by two- dimensional crystallization electron cryomicroscopy, and image analysis Methods in Enzymology. 294: 135-180. PMID 9916226 DOI: 10.1016/S0076-6879(99)94010-7  0.48
1998 Yeager M, Unger VM, Falk MM. Synthesis, assembly and structure of gap junction intercellular channels Current Opinion in Structural Biology. 8: 517-524. PMID 9729745 DOI: 10.1016/S0959-440X(98)80131-0  0.48
1998 Opalka N, Brugidou C, Bonneau C, Nicole M, Beachy RN, Yeager M, Fauquet C. Movement of rice yellow mottle virus between xylem cells through pit membranes. Proceedings of the National Academy of Sciences of the United States of America. 95: 3323-8. PMID 9501261 DOI: 10.1073/pnas.95.6.3323  0.48
1997 Unger VM, Kumar NM, Gilula NB, Yeager M. Projection structure of a gap junction membrane channel at 7 Å resolution Nature Structural Biology. 4: 39-43. PMID 8989321 DOI: 10.1038/nsb0197-39  0.48
1995 Mitra AK, van Hoek AN, Wiener MC, Verkman AS, Yeager M. The CHIP28 water channel visualized in ice by electron crystallography. Nature Structural Biology. 2: 726-9. PMID 7552739 DOI: 10.1038/nsb0995-726  0.48
1993 Dryden KA, Wang G, Yeager M, Nibert ML, Coombs KM, Furlong DB, Fields BN, Baker TS. Early steps in reovirus infection are associated with dramatic changes in supramolecular structure and protein conformation: Analysis of virions and subviral particles by cryoelectron microscopy and image reconstruction Journal of Cell Biology. 122: 1023-1041. PMID 8394844  0.48
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