Illme Schlichting - Publications

Affiliations: 
Max Planck Heidelberg, Heidelberg, Baden-Württemberg, Germany 

111 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Lindner R, Hartmann E, Tarnawski M, Winkler A, Frey D, Reinstein J, Meinhart A, Schlichting I. Photoactivation mechanism of a bacterial light-regulated adenylyl cyclase. Journal of Molecular Biology. PMID 28336405 DOI: 10.1016/j.jmb.2017.03.020  0.32
2016 Dagliyan O, Tarnawski M, Chu PH, Shirvanyants D, Schlichting I, Dokholyan NV, Hahn KM. Engineering extrinsic disorder to control protein activity in living cells. Science (New York, N.Y.). 354: 1441-1444. PMID 27980211 DOI: 10.1126/science.aah3404  0.32
2016 Ekeberg T, Svenda M, Seibert MM, Abergel C, Maia FR, Seltzer V, DePonte DP, Aquila A, Andreasson J, Iwan B, Jönsson O, Westphal D, Odić D, Andersson I, Barty A, ... ... Schlichting I, et al. Single-shot diffraction data from the Mimivirus particle using an X-ray free-electron laser. Scientific Data. 3: 160060. PMID 27479754 DOI: 10.1038/sdata.2016.60  0.32
2016 Wang H, Vilela M, Winkler A, Tarnawski M, Schlichting I, Yumerefendi H, Kuhlman B, Liu R, Danuser G, Hahn KM. LOVTRAP: an optogenetic system for photoinduced protein dissociation. Nature Methods. PMID 27427858 DOI: 10.1038/nmeth.3926  0.32
2016 Nass K, Meinhart A, Barends TR, Foucar L, Gorel A, Aquila A, Botha S, Doak RB, Koglin J, Liang M, Shoeman RL, Williams G, Boutet S, Schlichting I. Protein structure determination by single-wavelength anomalous diffraction phasing of X-ray free-electron laser data. Iucrj. 3: 180-91. PMID 27158504 DOI: 10.1107/S2052252516002980  0.32
2016 Colletier JP, Sliwa M, Gallat FX, Sugahara M, Guillon V, Schirò G, Coquelle N, Woodhouse J, Roux L, Gotthard G, Royant A, Uriarte LM, Ruckebusch C, Joti Y, Byrdin M, ... ... Schlichting I, et al. Serial Femtosecond Crystallography and Ultrafast Absorption Spectroscopy of the Photoswitchable Fluorescent Protein IrisFP. The Journal of Physical Chemistry Letters. PMID 26866390 DOI: 10.1021/acs.jpclett.5b02789  0.32
2016 Stan CA, Milathianaki D, Laksmono H, Sierra RG, McQueen TA, Messerschmidt M, Williams GJ, Koglin JE, Lane TJ, Hayes MJ, Guillet SAH, Liang M, Aquila AL, Willmott PR, Robinson JS, ... ... Schlichting I, et al. Liquid explosions induced by X-ray laser pulses Nature Physics. 12: 966-971. DOI: 10.1038/nphys3779  0.32
2016 Gorkhover T, Schorb S, Coffee R, Adolph M, Foucar L, Rupp D, Aquila A, Bozek JD, Epp SW, Erk B, Gumprecht L, Holmegaard L, Hartmann A, Hartmann R, Hauser G, ... ... Schlichting I, et al. Femtosecond and nanometre visualization of structural dynamics in superheated nanoparticles Nature Photonics. DOI: 10.1038/nphoton.2015.264  0.32
2015 Aquila A, Barty A, Bostedt C, Boutet S, Carini G, dePonte D, Drell P, Doniach S, Downing KH, Earnest T, Elmlund H, Elser V, Gühr M, Hajdu J, Hastings J, ... ... Schlichting I, et al. The linac coherent light source single particle imaging road map. Structural Dynamics (Melville, N.Y.). 2: 041701. PMID 26798801 DOI: 10.1063/1.4918726  0.32
2015 Galli L, Son SK, Barends TR, White TA, Barty A, Botha S, Boutet S, Caleman C, Doak RB, Nanao MH, Nass K, Shoeman RL, Timneanu N, Santra R, Schlichting I, et al. Towards phasing using high X-ray intensity. Iucrj. 2: 627-634. PMID 26594370 DOI: 10.1107/S2052252515014049  0.32
2015 Tarnawski M, Barends TR, Schlichting I. Structural analysis of an oxygen-regulated diguanylate cyclase. Acta Crystallographica. Section D, Biological Crystallography. 71: 2158-77. PMID 26527135 DOI: 10.1107/S139900471501545X  0.32
2015 Barends TR, Foucar L, Ardevol A, Nass K, Aquila A, Botha S, Doak RB, Falahati K, Hartmann E, Hilpert M, Heinz M, Hoffmann MC, Köfinger J, Koglin JE, Kovacsova G, ... ... Schlichting I, et al. Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation. Science (New York, N.Y.). PMID 26359336 DOI: 10.1126/science.aac5492  0.32
2015 Bublitz M, Nass K, Drachmann ND, Markvardsen AJ, Gutmann MJ, Barends TR, Mattle D, Shoeman RL, Doak RB, Boutet S, Messerschmidt M, Seibert MM, Williams GJ, Foucar L, Reinhard L, ... ... Schlichting I, et al. Structural studies of P-type ATPase-ligand complexes using an X-ray free-electron laser. Iucrj. 2: 409-20. PMID 26175901 DOI: 10.1107/S2052252515008969  0.32
2015 Barends T, White TA, Barty A, Foucar L, Messerschmidt M, Alonso-Mori R, Botha S, Chapman H, Doak RB, Galli L, Gati C, Gutmann M, Koglin J, Markvardsen A, Nass K, ... ... Schlichting I, et al. Effects of self-seeding and crystal post-selection on the quality of Monte Carlo-integrated SFX data. Journal of Synchrotron Radiation. 22: 644-52. PMID 25931080 DOI: 10.1107/S1600577515005184  0.32
2015 Boutet S, Foucar L, Barends TR, Botha S, Doak RB, Koglin JE, Messerschmidt M, Nass K, Schlichting I, Seibert MM, Shoeman RL, Williams GJ. Characterization and use of the spent beam for serial operation of LCLS. Journal of Synchrotron Radiation. 22: 634-43. PMID 25931079 DOI: 10.1107/S1600577515004002  0.32
2015 Feng Y, Alonso-Mori R, Barends TR, Blank VD, Botha S, Chollet M, Damiani DS, Doak RB, Glownia JM, Koglin JM, Lemke HT, Messerschmidt M, Nass K, Nelson S, Schlichting I, et al. Demonstration of simultaneous experiments using thin crystal multiplexing at the Linac Coherent Light Source. Journal of Synchrotron Radiation. 22: 626-33. PMID 25931078 DOI: 10.1107/S1600577515003999  0.32
2015 Schlichting I, White WE, Yabashi M. An introduction to the special issue on X-ray free-electron lasers. Journal of Synchrotron Radiation. 22: 471. PMID 25931054 DOI: 10.1107/S1600577515008176  0.32
2015 Nass K, Foucar L, Barends TR, Hartmann E, Botha S, Shoeman RL, Doak RB, Alonso-Mori R, Aquila A, Bajt S, Barty A, Bean R, Beyerlein KR, Bublitz M, Drachmann N, ... ... Schlichting I, et al. Indications of radiation damage in ferredoxin microcrystals using high-intensity X-FEL beams. Journal of Synchrotron Radiation. 22: 225-38. PMID 25723924 DOI: 10.1107/S1600577515002349  0.32
2015 Botha S, Nass K, Barends TR, Kabsch W, Latz B, Dworkowski F, Foucar L, Panepucci E, Wang M, Shoeman RL, Schlichting I, Doak RB. Room-temperature serial crystallography at synchrotron X-ray sources using slowly flowing free-standing high-viscosity microstreams. Acta Crystallographica. Section D, Biological Crystallography. 71: 387-97. PMID 25664750 DOI: 10.1107/S1399004714026327  0.32
2015 Winkler A, Barends TR, Udvarhelyi A, Lenherr-Frey D, Lomb L, Menzel A, Schlichting I. Structural details of light activation of the LOV2-based photoswitch PA-Rac1. Acs Chemical Biology. 10: 502-9. PMID 25368973 DOI: 10.1021/cb500744m  0.32
2014 Lee HH, Cherni I, Yu H, Fromme R, Doran JD, Grotjohann I, Mittman M, Basu S, Deb A, Dörner K, Aquila A, Barty A, Boutet S, Chapman HN, Doak RB, ... ... Schlichting I, et al. Expression, purification and crystallization of CTB-MPR, a candidate mucosal vaccine component against HIV-1. Iucrj. 1: 305-17. PMID 25295172 DOI: 10.1107/S2052252514014900  0.32
2014 Boll R, Rouzée A, Adolph M, Anielski D, Aquila A, Bari S, Bomme C, Bostedt C, Bozek JD, Chapman HN, Christensen L, Coffee R, Coppola N, De S, Decleva P, ... ... Schlichting I, et al. Imaging molecular structure through femtosecond photoelectron diffraction on aligned and oriented gas-phase molecules. Faraday Discussions. 171: 57-80. PMID 25290160 DOI: 10.1039/c4fd00037d  0.32
2014 Benjdia A, Heil K, Winkler A, Carell T, Schlichting I. Rescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyase. Chemical Communications (Cambridge, England). 50: 14201-4. PMID 25285338 DOI: 10.1039/c4cc05158k  0.32
2014 Sawaya MR, Cascio D, Gingery M, Rodriguez J, Goldschmidt L, Colletier JP, Messerschmidt MM, Boutet S, Koglin JE, Williams GJ, Brewster AS, Nass K, Hattne J, Botha S, Doak RB, ... ... Schlichting I, et al. Protein crystal structure obtained at 2.9 Å resolution from injecting bacterial cells into an X-ray free-electron laser beam. Proceedings of the National Academy of Sciences of the United States of America. 111: 12769-74. PMID 25136092 DOI: 10.1073/pnas.1413456111  0.32
2014 Arnlund D, Johansson LC, Wickstrand C, Barty A, Williams GJ, Malmerberg E, Davidsson J, Milathianaki D, DePonte DP, Shoeman RL, Wang D, James D, Katona G, Westenhoff S, White TA, ... ... Schlichting I, et al. Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser. Nature Methods. 11: 923-6. PMID 25108686 DOI: 10.1038/nmeth.3067  0.32
2014 Kerruth S, Ataka K, Frey D, Schlichting I, Heberle J. Aureochrome 1 illuminated: structural changes of a transcription factor probed by molecular spectroscopy. Plos One. 9: e103307. PMID 25058114 DOI: 10.1371/journal.pone.0103307  0.32
2014 Erk B, Boll R, Trippel S, Anielski D, Foucar L, Rudek B, Epp SW, Coffee R, Carron S, Schorb S, Ferguson KR, Swiggers M, Bozek JD, Simon M, Marchenko T, ... ... Schlichting I, et al. Imaging charge transfer in iodomethane upon x-ray photoabsorption. Science (New York, N.Y.). 345: 288-91. PMID 25035485 DOI: 10.1126/science.1253607  0.32
2014 Winkler A, Udvarhelyi A, Hartmann E, Reinstein J, Menzel A, Shoeman RL, Schlichting I. Characterization of elements involved in allosteric light regulation of phosphodiesterase activity by comparison of different functional BlrP1 states. Journal of Molecular Biology. 426: 853-68. PMID 24291457 DOI: 10.1016/j.jmb.2013.11.018  0.32
2014 Barends TR, Foucar L, Botha S, Doak RB, Shoeman RL, Nass K, Koglin JE, Williams GJ, Boutet S, Messerschmidt M, Schlichting I. De novo protein crystal structure determination from X-ray free-electron laser data. Nature. 505: 244-7. PMID 24270807 DOI: 10.1038/nature12773  0.32
2014 Küpper J, Stern S, Holmegaard L, Filsinger F, Rouzée A, Rudenko A, Johnsson P, Martin AV, Adolph M, Aquila A, Bajt S, Barty A, Bostedt C, Bozek J, Caleman C, ... ... Schlichting I, et al. X-ray diffraction from isolated and strongly aligned gas-phase molecules with a free-electron laser Physical Review Letters. 112. DOI: 10.1103/PhysRevLett.112.083002  0.32
2014 Rolles D, Boll R, Adolph M, Aquila A, Bostedt C, Bozek JD, Chapman HN, Coffee R, Coppola N, Decleva P, Delmas T, Epp SW, Erk B, Filsinger F, Foucar L, ... ... Schlichting I, et al. Femtosecond x-ray photoelectron diffraction on gas-phase dibromobenzene molecules Journal of Physics B: Atomic, Molecular and Optical Physics. 47. DOI: 10.1088/0953-4075/47/12/124035  0.32
2013 Johansson LC, Arnlund D, Katona G, White TA, Barty A, DePonte DP, Shoeman RL, Wickstrand C, Sharma A, Williams GJ, Aquila A, Bogan MJ, Caleman C, Davidsson J, Doak RB, ... ... Schlichting I, et al. Structure of a photosynthetic reaction centre determined by serial femtosecond crystallography. Nature Communications. 4: 2911. PMID 24352554 DOI: 10.1038/ncomms3911  0.32
2013 Kassemeyer S, Jafarpour A, Lomb L, Steinbrener J, Martin AV, Schlichting I. Optimal mapping of x-ray laser diffraction patterns into three dimensions using routing algorithms. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 88: 042710. PMID 24229216 DOI: 10.1103/PhysRevE.88.042710  0.32
2013 Demirci H, Sierra RG, Laksmono H, Shoeman RL, Botha S, Barends TR, Nass K, Schlichting I, Doak RB, Gati C, Williams GJ, Boutet S, Messerschmidt M, Jogl G, Dahlberg AE, et al. Serial femtosecond X-ray diffraction of 30S ribosomal subunit microcrystals in liquid suspension at ambient temperature using an X-ray free-electron laser. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 69: 1066-9. PMID 23989164 DOI: 10.1107/S174430911302099X  0.32
2013 Barends TR, Brosi RW, Steinmetz A, Scherer A, Hartmann E, Eschenbach J, Lorenz T, Seidel R, Shoeman RL, Zimmermann S, Bittl R, Schlichting I, Reinstein J. Combining crystallography and EPR: crystal and solution structures of the multidomain cochaperone DnaJ. Acta Crystallographica. Section D, Biological Crystallography. 69: 1540-52. PMID 23897477 DOI: 10.1107/S0907444913010640  0.32
2013 Loh ND, Starodub D, Lomb L, Hampton CY, Martin AV, Sierra RG, Barty A, Aquila A, Schulz J, Steinbrener J, Shoeman RL, Kassemeyer S, Bostedt C, Bozek J, Epp SW, ... ... Schlichting I, et al. Sensing the wavefront of x-ray free-electron lasers using aerosol spheres. Optics Express. 21: 12385-94. PMID 23736456 DOI: 10.1364/OE.21.012385  0.32
2013 Tarnawski M, Barends TR, Hartmann E, Schlichting I. Structures of the catalytic EAL domain of the Escherichia coli direct oxygen sensor. Acta Crystallographica. Section D, Biological Crystallography. 69: 1045-53. PMID 23695249 DOI: 10.1107/S0907444913004423  0.32
2013 Barends TR, Foucar L, Shoeman RL, Bari S, Epp SW, Hartmann R, Hauser G, Huth M, Kieser C, Lomb L, Motomura K, Nagaya K, Schmidt C, Strecker R, Anielski D, ... ... Schlichting I, et al. Anomalous signal from S atoms in protein crystallographic data from an X-ray free-electron laser. Acta Crystallographica. Section D, Biological Crystallography. 69: 838-42. PMID 23633593 DOI: 10.1107/S0907444913002448  0.32
2013 Yang L, Nelson RS, Benjdia A, Lin G, Telser J, Stoll S, Schlichting I, Li L. A radical transfer pathway in spore photoproduct lyase. Biochemistry. 52: 3041-50. PMID 23607538 DOI: 10.1021/bi3016247  0.32
2013 Redecke L, Nass K, DePonte DP, White TA, Rehders D, Barty A, Stellato F, Liang M, Barends TR, Boutet S, Williams GJ, Messerschmidt M, Seibert MM, Aquila A, Arnlund D, ... ... Schlichting I, et al. Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser. Science (New York, N.Y.). 339: 227-30. PMID 23196907 DOI: 10.1126/science.1229663  0.32
2013 Duhme N, Schweizer PA, Thomas D, Becker R, Schröter J, Barends TR, Schlichting I, Draguhn A, Bruehl C, Katus HA, Koenen M. Altered HCN4 channel C-linker interaction is associated with familial tachycardia-bradycardia syndrome and atrial fibrillation. European Heart Journal. 34: 2768-75. PMID 23178648 DOI: 10.1093/eurheartj/ehs391  0.32
2013 Park HJ, Loh ND, Sierra RG, Hampton CY, Starodub D, Martin AV, Barty A, Aquila A, Schulz J, Steinbrener J, Shoeman RL, Lomb L, Kassemeyer S, Bostedt C, Bozek J, ... ... Schlichting I, et al. Toward unsupervised single-shot diffractive imaging of heterogeneous particles using X-ray free-electron lasers Optics Express. 21: 28729-28742. DOI: 10.1364/OE.21.028729  0.32
2013 Erk B, Rolles D, Foucar L, Rudek B, Epp SW, Cryle M, Bostedt C, Schorb S, Bozek J, Rouzee A, Hundertmark A, Marchenko T, Simon M, Filsinger F, Christensen L, ... ... Schlichting I, et al. Ultrafast Charge Rearrangement and Nuclear Dynamics upon Inner-Shell Multiple Ionization of Small Polyatomic Molecules Physical Review Letters. 110. DOI: 10.1103/PhysRevLett.110.053003  0.32
2013 Rudek B, Rolles D, Son SK, Foucar L, Erk B, Epp S, Boll R, Anielski D, Bostedt C, Schorb S, Coffee R, Bozek J, Trippel S, Marchenko T, Simon M, ... ... Schlichting I, et al. Resonance-enhanced multiple ionization of krypton at an x-ray free-electron laser Physical Review a - Atomic, Molecular, and Optical Physics. 87. DOI: 10.1103/PhysRevA.87.023413  0.32
2013 Pedersoli E, Loh ND, Capotondi F, Hampton CY, Sierra RG, Starodub D, Bostedt C, Bozek J, Nelson AJ, Aslam M, Li S, Dravid VP, Martin AV, Aquila A, Barty A, ... ... Schlichting I, et al. Mesoscale morphology of airborne core-shell nanoparticle clusters: X-ray laser coherent diffraction imaging Journal of Physics B: Atomic, Molecular and Optical Physics. 46. DOI: 10.1088/0953-4075/46/16/164033  0.32
2013 Erk B, Rolles D, Foucar L, Rudek B, Epp SW, Cryle M, Bostedt C, Schorb S, Bozek J, Rouzee A, Hundertmark A, Marchenko T, Simon M, Filsinger F, Christensen L, ... ... Schlichting I, et al. Inner-shell multiple ionization of polyatomic molecules with an intense x-ray free-electron laser studied by coincident ion momentum imaging Journal of Physics B: Atomic, Molecular and Optical Physics. 46. DOI: 10.1088/0953-4075/46/16/164031  0.32
2012 Barty A, Caleman C, Aquila A, Timneanu N, Lomb L, White TA, Andreasson J, Arnlund D, Bajt S, Barends TR, Barthelmess M, Bogan MJ, Bostedt C, Bozek JD, Coffee R, ... ... Schlichting I, et al. Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements. Nature Photonics. 6: 35-40. PMID 24078834 DOI: 10.1038/nphoton.2011.297  0.32
2012 Starodub D, Aquila A, Bajt S, Barthelmess M, Barty A, Bostedt C, Bozek JD, Coppola N, Doak RB, Epp SW, Erk B, Foucar L, Gumprecht L, Hampton CY, Hartmann A, ... ... Schlichting I, et al. Single-particle structure determination by correlations of snapshot X-ray diffraction patterns. Nature Communications. 3: 1276. PMID 23232406 DOI: 10.1038/ncomms2288  0.32
2012 Schlichting I, Miao J. Emerging opportunities in structural biology with X-ray free-electron lasers. Current Opinion in Structural Biology. 22: 613-26. PMID 22922042 DOI: 10.1016/j.sbi.2012.07.015  0.32
2012 Loh ND, Hampton CY, Martin AV, Starodub D, Sierra RG, Barty A, Aquila A, Schulz J, Lomb L, Steinbrener J, Shoeman RL, Kassemeyer S, Bostedt C, Bozek J, Epp SW, ... ... Schlichting I, et al. Fractal morphology, imaging and mass spectrometry of single aerosol particles in flight. Nature. 486: 513-7. PMID 22739316 DOI: 10.1038/nature11222  0.32
2012 Martin AV, Loh ND, Hampton CY, Sierra RG, Wang F, Aquila A, Bajt S, Barthelmess M, Bostedt C, Bozek JD, Coppola N, Epp SW, Erk B, Fleckenstein H, Foucar L, ... ... Schlichting I, et al. Femtosecond dark-field imaging with an X-ray free electron laser. Optics Express. 20: 13501-12. PMID 22714377  0.32
2012 Boutet S, Lomb L, Williams GJ, Barends TR, Aquila A, Doak RB, Weierstall U, DePonte DP, Steinbrener J, Shoeman RL, Messerschmidt M, Barty A, White TA, Kassemeyer S, Kirian RA, ... ... Schlichting I, et al. High-resolution protein structure determination by serial femtosecond crystallography. Science (New York, N.Y.). 337: 362-4. PMID 22653729 DOI: 10.1126/science.1217737  0.32
2012 Kassemeyer S, Steinbrener J, Lomb L, Hartmann E, Aquila A, Barty A, Martin AV, Hampton CY, Bajt S, Barthelmess M, Barends TR, Bostedt C, Bott M, Bozek JD, Coppola N, ... ... Schlichting I, et al. Femtosecond free-electron laser x-ray diffraction data sets for algorithm development. Optics Express. 20: 4149-58. PMID 22418172 DOI: 10.1364/OE.20.004149  0.32
2012 Aquila A, Hunter MS, Doak RB, Kirian RA, Fromme P, White TA, Andreasson J, Arnlund D, Bajt S, Barends TR, Barthelmess M, Bogan MJ, Bostedt C, Bottin H, Bozek JD, ... ... Schlichting I, et al. Time-resolved protein nanocrystallography using an X-ray free-electron laser. Optics Express. 20: 2706-16. PMID 22330507 DOI: 10.1364/OE.20.002706  0.32
2012 Koopmann R, Cupelli K, Redecke L, Nass K, Deponte DP, White TA, Stellato F, Rehders D, Liang M, Andreasson J, Aquila A, Bajt S, Barthelmess M, Barty A, Bogan MJ, ... ... Schlichting I, et al. In vivo protein crystallization opens new routes in structural biology. Nature Methods. 9: 259-62. PMID 22286384 DOI: 10.1038/nmeth.1859  0.32
2012 Johansson LC, Arnlund D, White TA, Katona G, Deponte DP, Weierstall U, Doak RB, Shoeman RL, Lomb L, Malmerberg E, Davidsson J, Nass K, Liang M, Andreasson J, Aquila A, ... ... Schlichting I, et al. Lipidic phase membrane protein serial femtosecond crystallography. Nature Methods. 9: 263-5. PMID 22286383 DOI: 10.1038/nmeth.1867  0.32
2012 Martin AV, Wang F, Loh ND, Ekeberg T, Maia FRNC, Hantke M, Van Der Schot G, Hampton CY, Sierra RG, Aquila A, Bajt S, Barthelmess M, Bostedt C, Bozek JD, Coppola N, ... ... Schlichting I, et al. Noise-robust coherent diffractive imaging with a single diffraction pattern Optics Express. 20: 16650-16661. DOI: 10.1364/OE.20.016650  0.32
2012 Duane Loh N, Starodub D, Lomb L, Hampton CY, Martin AV, Sierra RG, Barty A, Aquila A, Schulz J, Steinbrener J, Shoeman RL, Kassemeyer S, Bostedt C, Bozek J, Epp SW, ... ... Schlichting I, et al. Profiling structured beams using injected aerosols Proceedings of Spie - the International Society For Optical Engineering. 8504. DOI: 10.1117/12.930075  0.32
2012 Gorkhover T, Adolph M, Rupp D, Schorb S, Epp SW, Erk B, Foucar L, Hartmann R, Kimmel N, Kühnel KU, Rolles D, Rudek B, Rudenko A, Andritschke R, Aquila A, ... ... Schlichting I, et al. Nanoplasma dynamics of single large xenon clusters irradiated with superintense X-ray pulses from the linac coherent light source free-electron laser Physical Review Letters. 108. DOI: 10.1103/PhysRevLett.108.245005  0.32
2012 Erk B, Rudenko A, Rolles D, Rudek B, Foucar L, Epp S, Cryle M, Schlichting I, Bostedt C, Schorb S, Bozek J, Rouzee A, Hundertmark A, Marchenko T, Simon M, et al. Coulomb explosion imaging of small organic molecules at LCLS Journal of Physics: Conference Series. 388. DOI: 10.1088/1742-6596/388/2/022108  0.32
2012 Osipov T, Rolles D, Bostedt C, Castagna JC, Hartmann R, Bozek JD, Schlichting I, Strüder L, Ullrich J, Berrah N. Next generation endstation for concurrent measurements of charged products and photons in LCLS FEL experiments Journal of Physics: Conference Series. 388. DOI: 10.1088/1742-6596/388/14/142025  0.32
2012 Rudek B, Son SK, Foucar L, Epp SW, Erk B, Hartmann R, Adolph M, Andritschke R, Aquila A, Berrah N, Bostedt C, Bozek J, Coppola N, Filsinger F, Gorke H, ... ... Schlichting I, et al. Ultra-efficient ionization of heavy atoms by intense X-ray free-electron laser pulses Nature Photonics. 6: 858-865. DOI: 10.1038/nphoton.2012.261  0.32
2011 Lomb L, Barends TR, Kassemeyer S, Aquila A, Epp SW, Erk B, Foucar L, Hartmann R, Rudek B, Rolles D, Rudenko A, Shoeman RL, Andreasson J, Bajt S, Barthelmess M, ... ... Schlichting I, et al. Radiation damage in protein serial femtosecond crystallography using an x-ray free-electron laser. Physical Review. B, Condensed Matter and Materials Physics. 84: 214111. PMID 24089594 DOI: 10.1103/PhysRevB.84.214111  0.32
2011 Smeulders MJ, Barends TR, Pol A, Scherer A, Zandvoort MH, Udvarhelyi A, Khadem AF, Menzel A, Hermans J, Shoeman RL, Wessels HJ, van den Heuvel LP, Russ L, Schlichting I, Jetten MS, et al. Evolution of a new enzyme for carbon disulphide conversion by an acidothermophilic archaeon. Nature. 478: 412-6. PMID 22012399 DOI: 10.1038/nature10464  0.32
2011 Yoon CH, Schwander P, Abergel C, Andersson I, Andreasson J, Aquila A, Bajt S, Barthelmess M, Barty A, Bogan MJ, Bostedt C, Bozek J, Chapman HN, Claverie JM, Coppola N, ... ... Schlichting I, et al. Unsupervised classification of single-particle X-ray diffraction snapshots by spectral clustering. Optics Express. 19: 16542-9. PMID 21935018 DOI: 10.1364/OE.19.016542  0.32
2011 Seibert MM, Ekeberg T, Maia FR, Svenda M, Andreasson J, Jönsson O, Odi? D, Iwan B, Rocker A, Westphal D, Hantke M, DePonte DP, Barty A, Schulz J, Gumprecht L, ... ... Schlichting I, et al. Single mimivirus particles intercepted and imaged with an X-ray laser. Nature. 470: 78-81. PMID 21293374 DOI: 10.1038/nature09748  0.32
2011 Chapman HN, Fromme P, Barty A, White TA, Kirian RA, Aquila A, Hunter MS, Schulz J, DePonte DP, Weierstall U, Doak RB, Maia FR, Martin AV, Schlichting I, Lomb L, et al. Femtosecond X-ray protein nanocrystallography. Nature. 470: 73-7. PMID 21293373 DOI: 10.1038/nature09750  0.32
2011 Lai J, Niks D, Wang Y, Domratcheva T, Barends TR, Schwarz F, Olsen RA, Elliott DW, Fatmi MQ, Chang CE, Schlichting I, Dunn MF, Mueller LJ. X-ray and NMR crystallography in an enzyme active site: the indoline quinonoid intermediate in tryptophan synthase. Journal of the American Chemical Society. 133: 4-7. PMID 21142052 DOI: 10.1021/ja106555c  0.32
2011 Martin AV, Andreasson J, Aquila A, Bajt S, Barends TRM, Barthelmess M, Barty A, Benner WH, Bostedt C, Bozek JD, Bucksbaum P, Caleman C, Coppola N, DePonte DP, Ekeberg T, ... ... Schlichting I, et al. Single particle imaging with soft x-rays at the linac coherent light source Proceedings of Spie - the International Society For Optical Engineering. 8078. DOI: 10.1117/12.886754  0.32
2010 Loh ND, Bogan MJ, Elser V, Barty A, Boutet S, Bajt S, Hajdu J, Ekeberg T, Maia FR, Schulz J, Seibert MM, Iwan B, Timneanu N, Marchesini S, Schlichting I, et al. Cryptotomography: reconstructing 3D Fourier intensities from randomly oriented single-shot diffraction patterns. Physical Review Letters. 104: 225501. PMID 20867179 DOI: 10.1103/PhysRevLett.104.225501  0.32
2010 Bogan MJ, Boutet S, Barty A, Benner WH, Frank M, Lomb L, Shoeman R, Starodub D, Seibert MM, Hau-Riege SP, Woods B, Decorwin-Martin P, Bajt S, Schulz J, Rohner U, ... ... Schlichting I, et al. Single-shot femtosecond x-ray diffraction from randomly oriented ellipsoidal nanoparticles Physical Review Special Topics - Accelerators and Beams. 13. DOI: 10.1103/PhysRevSTAB.13.094701  0.32
2010 Strüder L, Epp S, Rolles D, Hartmann R, Holl P, Lutz G, Soltau H, Eckart R, Reich C, Heinzinger K, Thamm C, Rudenko A, Krasniqi F, Kühnel KU, Bauer C, ... ... Schlichting I, et al. Large-format, high-speed, X-ray pnCCDs combined with electron and ion imaging spectrometers in a multipurpose chamber for experiments at 4th generation light sources Nuclear Instruments and Methods in Physics Research, Section a: Accelerators, Spectrometers, Detectors and Associated Equipment. 614: 483-496. DOI: 10.1016/j.nima.2009.12.053  0.32
2009 Wu YI, Frey D, Lungu OI, Jaehrig A, Schlichting I, Kuhlman B, Hahn KM. A genetically encoded photoactivatable Rac controls the motility of living cells. Nature. 461: 104-8. PMID 19693014 DOI: 10.1038/nature08241  0.32
2009 Glas AF, Maul MJ, Cryle M, Barends TRM, Schneider S, Kaya E, Schlichting I, Carell T. The archaeal cofactor F0 is a light-harvesting antenna chromophore in eukaryotes Proceedings of the National Academy of Sciences of the United States of America. 106: 11540-11545. PMID 19570997 DOI: 10.1073/pnas.0812665106  0.32
2009 Barends TR, Hartmann E, Griese JJ, Beitlich T, Kirienko NV, Ryjenkov DA, Reinstein J, Shoeman RL, Gomelsky M, Schlichting I. Structure and mechanism of a bacterial light-regulated cyclic nucleotide phosphodiesterase. Nature. 459: 1015-8. PMID 19536266 DOI: 10.1038/nature07966  0.32
2009 Novak WR, Moulin AG, Blakeley MP, Schlichting I, Petsko GA, Ringe D. A preliminary neutron diffraction study of gamma-chymotrypsin. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 65: 317-20. PMID 19255494 DOI: 10.1107/S1744309109006630  0.32
2008 Maul MJ, Barends TRM, Glas AF, Cryle MJ, Domratcheva T, Schneider S, Schlichting I, Carell T. Crystal structure and mechanism of a DNA (6-4) photolyase Angewandte Chemie - International Edition. 47: 10076-10080. PMID 18956392 DOI: 10.1002/anie.200804268  0.32
2008 Chen H, Hirao H, Derat E, Schlichting I, Shaik S. Quantum mechanical/molecular mechanical study on the mechanisms of compound I formation in the catalytic cycle of chloroperoxidase: an overview on heme enzymes. The Journal of Physical Chemistry. B. 112: 9490-500. PMID 18597525 DOI: 10.1021/jp803010f  0.32
2008 Kühnel K, Ke N, Cryle MJ, Sligar SG, Schuler MA, Schlichting I. Crystal structures of substrate-free and retinoic acid-bound cyanobacterial cytochrome P450 CYP120A1. Biochemistry. 47: 6552-9. PMID 18512957 DOI: 10.1021/bi800328s  0.32
2007 Makris TM, von Koenig K, Schlichting I, Sligar SG. Alteration of P450 distal pocket solvent leads to impaired proton delivery and changes in heme geometry. Biochemistry. 46: 14129-40. PMID 18001135 DOI: 10.1021/bi7013695  0.32
2007 Kühnel K, Derat E, Terner J, Shaik S, Schlichting I. Structure and quantum chemical characterization of chloroperoxidase compound 0, a common reaction intermediate of diverse heme enzymes. Proceedings of the National Academy of Sciences of the United States of America. 104: 99-104. PMID 17190816 DOI: 10.1073/pnas.0606285103  0.32
2006 Blankenfeldt W, Thomä NH, Wray JS, Gautel M, Schlichting I. Crystal structures of human cardiac beta-myosin II S2-Delta provide insight into the functional role of the S2 subfragment. Proceedings of the National Academy of Sciences of the United States of America. 103: 17713-7. PMID 17095604 DOI: 10.1073/pnas.0606741103  0.32
2006 Makris TM, von Koenig K, Schlichting I, Sligar SG. The status of high-valent metal oxo complexes in the P450 cytochromes. Journal of Inorganic Biochemistry. 100: 507-18. PMID 16510191 DOI: 10.1016/j.jinorgbio.2006.01.025  0.32
2006 Zirak P, Penzkofer A, Schiereis T, Hegemann P, Jung A, Schlichting I. Photodynamics of the small BLUF protein BlrB from Rhodobacter sphaeroides. Journal of Photochemistry and Photobiology. B, Biology. 83: 180-94. PMID 16495071 DOI: 10.1016/j.jphotobiol.2005.12.015  0.32
2005 Jung A, Domratcheva T, Tarutina M, Wu Q, Ko WH, Shoeman RL, Gomelsky M, Gardner KH, Schlichting I. Structure of a bacterial BLUF photoreceptor: Insights into blue light-mediated signal transduction Proceedings of the National Academy of Sciences of the United States of America. 102: 12350-12355. PMID 16107542 DOI: 10.1073/pnas.0500722102  0.32
2005 Matter H, Kumar HSA, Fedorov R, Frey A, Kotsonis P, Hartmann E, Fröhlich LG, Reif A, Pfleiderer W, Scheurer P, Ghosh DK, Schlichting I, Schmidt HHHW. Structural analysis of isoform-specific inhibitors targeting the tetrahydrobiopterin binding site of human nitric oxide synthases Journal of Medicinal Chemistry. 48: 4783-4792. PMID 16033258 DOI: 10.1021/jm050007x  0.32
2005 Denisov IG, Makris TM, Sligar SG, Schlichting I. Structure and chemistry of cytochrome P450. Chemical Reviews. 105: 2253-77. PMID 15941214 DOI: 10.1021/cr0307143  0.32
2004 Wade RC, Winn PJ, Schlichting I, Sudarko. A survey of active site access channels in cytochromes P450. Journal of Inorganic Biochemistry. 98: 1175-82. PMID 15219983 DOI: 10.1016/j.jinorgbio.2004.02.007  0.32
2003 Kottke T, Dick B, Fedorov R, Schlichting I, Deutzmann R, Hegemann P. Irreversible photoreduction of flavin in a mutated Phot-LOV1 domain. Biochemistry. 42: 9854-62. PMID 12924934 DOI: 10.1021/bi034863r  0.32
2003 Pylypenko O, Vitali F, Zerbe K, Robinson JA, Schlichting I. Crystal structure of OxyC, a cytochrome P450 implicated in an oxidative C-C coupling reaction during vancomycin biosynthesis. The Journal of Biological Chemistry. 278: 46727-33. PMID 12888556 DOI: 10.1074/jbc.M306486200  0.32
2003 Fedorov R, Schlichting I, Hartmann E, Domratcheva T, Fuhrmann M, Hegemann P. Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii. Biophysical Journal. 84: 2474-82. PMID 12668455 DOI: 10.1016/S0006-3495(03)75052-8  0.32
2003 Pylypenko O, Rak A, Reents R, Niculae A, Sidorovitch V, Cioaca MD, Bessolitsyna E, Thomä NH, Waldmann H, Schlichting I, Goody RS, Alexandrov K. Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase. Molecular Cell. 11: 483-94. PMID 12620235 DOI: 10.1016/S1097-2765(03)00044-3  0.32
2002 Groot ML, Vos MH, Schlichting I, van Mourik F, Joffre M, Lambry JC, Martin JL. Coherent infrared emission from myoglobin crystals: an electric field measurement. Proceedings of the National Academy of Sciences of the United States of America. 99: 1323-8. PMID 11818575 DOI: 10.1073/pnas.251662698  0.32
2001 Rak A, Reents R, Pylypenko O, Niculae A, Sidorovitch V, Thomä NH, Waldmann H, Schlichting I, Goody RS, Alexandrov K. Crystallization and preliminary X-ray diffraction analysis of the Rab escort protein-1 in complex with Rab geranylgeranyltransferase Journal of Structural Biology. 136: 158-161. PMID 11886217 DOI: 10.1006/jsbi.2001.4433  0.32
2000 Ostermann N, Lavie A, Padiyar S, Brundiers R, Veit T, Reinstein J, Goody RS, Konrad M, Schlichting I. Potentiating AZT activation: Structures of wild-type and mutant human thymidylate kinase suggest reasons for the mutants' improved kinetics with the HIV prodrug metabolite AZTMP Journal of Molecular Biology. 304: 43-53. PMID 11071809 DOI: 10.1006/jmbi.2000.4175  0.32
2000 Ostermann N, Schlichting I, Brundiers R, Konrad M, Reinstein J, Veit T, Goody RS, Lavie A. Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate Structure. 8: 629-642. PMID 10873853 DOI: 10.1016/S0969-2126(00)00149-0  0.32
2000 Schlichting I, Berendzen J, Chu K, Stock AM, Maves SA, Benson DE, Sweet RM, Ringe D, Petsko GA, Sligar SG. The catalytic pathway of cytochrome p450cam at atomic resolution. Science (New York, N.Y.). 287: 1615-22. PMID 10698731 DOI: 10.1126/science.287.5458.1615  0.32
1999 Brundiers R, Lavie A, Veit T, Reinstein J, Schlichting I, Ostermann N, Goody RS, Konrad M. Modifying human thymidylate kinase to potentiate azidothymidine activation Journal of Biological Chemistry. 274: 35289-35292. PMID 10585390 DOI: 10.1074/jbc.274.50.35289  0.32
1998 Lavie A, Ostermann N, Brundiers R, Goody RS, Reinstein J, Konrad M, Schlichting I. Structural basis for efficient phosphorylation of 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase Proceedings of the National Academy of Sciences of the United States of America. 95: 14045-14050. PMID 9826650 DOI: 10.1073/pnas.95.24.14045  0.32
1998 Hasson MS, Schlichting I, Moulai J, Taylor K, Barrett W, Kenyon GL, Babbitt PC, Gerlt JA, Petsko GA, Ringe D. Evolution of an enzyme active site: the structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase. Proceedings of the National Academy of Sciences of the United States of America. 95: 10396-401. PMID 9724714 DOI: 10.1073/pnas.95.18.10396  0.32
1998 Lavie A, Konrad M, Brundiers R, Goody RS, Schlichting I, Reinstein J. Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5'-adenosyl) P5-(5'-thymidyl) pentaphosphate (TP5A) at 2.0 Å resolution: Implications for catalysis and AZT activation Biochemistry. 37: 3677-3686. PMID 9521686 DOI: 10.1021/bi9720787  0.32
1998 Balzarini J, Degreve B, De Clercq E, Lavie A, Reinstein J, Goody RS, Schlichting I. Improving AZT efficacy Nature Medicine. 4: 132. PMID 9461164  0.32
1997 Hasson MS, Schlichting I, McGowen MM, Woolridge EM, Kozarich JW, Petsko GA, Ringe D. Characterization of two crystal forms of 3-carboxy-cis,cis-muconate lactonizing enzyme from Pseudomonas putida. Acta Crystallographica. Section D, Biological Crystallography. 53: 352-3. PMID 15299946 DOI: 10.1107/S0907444996015648  0.32
1997 Lavie A, Schlichting I, Vetter IR, Konrad M, Reinstein J, Goody RS. The bottleneck in AZT activation Nature Medicine. 3: 922-924. PMID 9256287 DOI: 10.1038/nm0897-922  0.32
1997 Lavie A, Vetter IR, Konrad M, Goody RS, Reinstein J, Schlichting I. Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation Nature Structural Biology. 4: 601-604. PMID 9253404 DOI: 10.1038/nsb0897-601  0.32
1994 Lantwin CB, Schlichting I, Kabsch W, Pai EF, Krauth-Siegel RL. The structure of Trypanosoma cruzi trypanothione reductase in the oxidized and NADPH reduced state Proteins: Structure, Function and Genetics. 18: 161-173. PMID 8159665  0.32
1994 Xie X, Harrison DH, Schlichting I, Sweet RM, Kalabokis VN, Szent-Györgyi AG, Cohen C. Structure of the regulatory domain of scallop myosin at 2.8 A resolution. Nature. 368: 306-12. PMID 8127365 DOI: 10.1038/368306a0  0.32
1992 Goody RS, Pai EF, Schlichting I, Rensland H, Scheidig A, Franken S, Wittinghofer A. Studies on the structure and mechanism of H-ras p21 Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 336: 3-10; discussion 10. PMID 1351293  0.32
1990 Krengel U, Schlichting I, Scherer A, Schumann R, Frech M, John J, Kabsch W, Pai EF, Wittinghofer A. Three-dimensional structures of H-ras p21 mutants: Molecular basis for their inability to function as signal switch molecules Cell. 62: 539-548. PMID 2199064 DOI: 10.1016/0092-8674(90)90018-A  0.32
1990 Schlichting I, Almo SC, Rapp G, Wilson K, Petratos K, Lentfer A, Wittinghofer A, Kabsch W, Pai EF, Petsko GA, Goody RS. Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis Nature. 345: 309-315. PMID 2111463 DOI: 10.1038/345309a0  0.32
1989 Schlichting I, Rapp G, John J, Wittinghofer A, Pai EF, Goody RS. Biochemical and crystallographic characterization of a complex of c-Ha-ras p21 and caged GTP with flash photolysis Proceedings of the National Academy of Sciences of the United States of America. 86: 7687-7690. PMID 2682619  0.32
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