Bryan C. Hains - Publications

Affiliations: 
Yale University, New Haven, CT 
Area:
spinal cord injury, pain

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Tan AM, Chang YW, Zhao P, Hains BC, Waxman SG. Rac1-regulated dendritic spine remodeling contributes to neuropathic pain after peripheral nerve injury. Experimental Neurology. 232: 222-33. PMID 21963650 DOI: 10.1016/j.expneurol.2011.08.028  1
2011 Hains B, Vera-Portocarrero LP. Animal models of central neuropathic pain Neuromethods. 49: 103-115. DOI: 10.1007/978-1-60761-880-5_7  1
2009 Tan AM, Choi JS, Waxman SG, Hains BC. Dendritic spine remodeling after spinal cord injury alters neuronal signal processing. Journal of Neurophysiology. 102: 2396-409. PMID 19692517 DOI: 10.1152/jn.00095.2009  1
2009 Tan AM, Zhao P, Waxman SG, Hains BC. Early microglial inhibition preemptively mitigates chronic pain development after experimental spinal cord injury. Journal of Rehabilitation Research and Development. 46: 123-33. PMID 19533525  1
2009 Hulsebosch CE, Hains BC, Crown ED, Carlton SM. Mechanisms of chronic central neuropathic pain after spinal cord injury. Brain Research Reviews. 60: 202-13. PMID 19154757 DOI: 10.1016/j.brainresrev.2008.12.010  1
2009 Saab CY, Hains BC. Remote neuroimmune signaling: a long-range mechanism of nociceptive network plasticity. Trends in Neurosciences. 32: 110-7. PMID 19135730 DOI: 10.1016/j.tins.2008.11.004  1
2009 Blumenfeld H, Lampert A, Klein JP, Mission J, Chen MC, Rivera M, Dib-Hajj S, Brennan AR, Hains BC, Waxman SG. Role of hippocampal sodium channel Nav1.6 in kindling epileptogenesis. Epilepsia. 50: 44-55. PMID 18637833 DOI: 10.1111/j.1528-1167.2008.01710.x  1
2008 Tan AM, Stamboulian S, Chang YW, Zhao P, Hains AB, Waxman SG, Hains BC. Neuropathic pain memory is maintained by Rac1-regulated dendritic spine remodeling after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13173-83. PMID 19052208 DOI: 10.1523/JNEUROSCI.3142-08.2008  1
2008 Saab CY, Waxman SG, Hains BC. Alarm or curse? The pain of neuroinflammation. Brain Research Reviews. 58: 226-35. PMID 18486228 DOI: 10.1016/j.brainresrev.2008.04.002  1
2008 Deumens R, Joosten EA, Waxman SG, Hains BC. Locomotor dysfunction and pain: the scylla and charybdis of fiber sprouting after spinal cord injury. Molecular Neurobiology. 37: 52-63. PMID 18415034 DOI: 10.1007/s12035-008-8016-1  1
2008 Lin ZP, Zhu YL, Johnson DR, Rice KP, Nottoli T, Hains BC, McGrath J, Waxman SG, Sartorelli AC. Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response. Molecular Pharmacology. 73: 243-51. PMID 17959714 DOI: 10.1124/mol.107.039594  1
2008 Dib-Hajj SD, Hains BC, Black JA, Waxman SG. Voltage-Gated Sodium Channels: Multiple Roles in the Pathophysiology of Pain Structure, Function, and Modulation of Neuronal Voltagegated Ion Channels. 67-104. DOI: 10.1002/9780470429907.ch3  1
2007 Zhao P, Waxman SG, Hains BC. Modulation of thalamic nociceptive processing after spinal cord injury through remote activation of thalamic microglia by cysteine cysteine chemokine ligand 21. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 8893-902. PMID 17699671 DOI: 10.1523/JNEUROSCI.2209-07.2007  1
2007 Hains BC, Waxman SG. Sodium channel expression and the molecular pathophysiology of pain after SCI. Progress in Brain Research. 161: 195-203. PMID 17618978 DOI: 10.1016/S0079-6123(06)61013-3  1
2007 Woolfe F, Waxman SG, Hains BC. In silico modeling of axonal reconnection within a discrete fiber tract after spinal cord injury. Journal of Neurotrauma. 24: 421-32. PMID 17376004 DOI: 10.1089/neu.2006.0131  1
2007 Zhao P, Waxman SG, Hains BC. Extracellular signal-regulated kinase-regulated microglia-neuron signaling by prostaglandin E2 contributes to pain after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2357-68. PMID 17329433 DOI: 10.1523/JNEUROSCI.0138-07.2007  1
2006 Black JA, Liu S, Hains BC, Saab CY, Waxman SG. Long-term protection of central axons with phenytoin in monophasic and chronic-relapsing EAE. Brain : a Journal of Neurology. 129: 3196-208. PMID 16931536 DOI: 10.1093/brain/awl216  1
2006 Zhao P, Waxman SG, Hains BC. Sodium channel expression in the ventral posterolateral nucleus of the thalamus after peripheral nerve injury. Molecular Pain. 2: 27. PMID 16916452 DOI: 10.1186/1744-8069-2-27  1
2006 Lampert A, Hains BC, Waxman SG. Upregulation of persistent and ramp sodium current in dorsal horn neurons after spinal cord injury. Experimental Brain Research. 174: 660-6. PMID 16718433 DOI: 10.1007/s00221-006-0511-x  1
2006 Hains BC, Waxman SG. Activated microglia contribute to the maintenance of chronic pain after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4308-17. PMID 16624951 DOI: 10.1523/JNEUROSCI.0003-06.2006  1
2006 Waxman SG, Hains BC. Fire and phantoms after spinal cord injury: Na+ channels and central pain. Trends in Neurosciences. 29: 207-15. PMID 16494954 DOI: 10.1016/j.tins.2006.02.003  1
2006 Hains BC, Saab CY, Waxman SG. Alterations in burst firing of thalamic VPL neurons and reversal by Na(v)1.3 antisense after spinal cord injury. Journal of Neurophysiology. 95: 3343-52. PMID 16481457 DOI: 10.1152/jn.01009.2005  1
2006 Sasaki M, Hains BC, Lankford KL, Waxman SG, Kocsis JD. Protection of corticospinal tract neurons after dorsal spinal cord transection and engraftment of olfactory ensheathing cells. Glia. 53: 352-9. PMID 16288464 DOI: 10.1002/glia.20285  1
2005 Hains BC, Waxman SG. Neuroprotection by sodium channel blockade with phenytoin in an experimental model of glaucoma. Investigative Ophthalmology & Visual Science. 46: 4164-9. PMID 16249495 DOI: 10.1167/iovs.05-0618  1
2005 Hains BC, Saab CY, Waxman SG. Changes in electrophysiological properties and sodium channel Nav1.3 expression in thalamic neurons after spinal cord injury. Brain : a Journal of Neurology. 128: 2359-71. PMID 16109750 DOI: 10.1093/brain/awh623  1
2005 Craner MJ, Damarjian TG, Liu S, Hains BC, Lo AC, Black JA, Newcombe J, Cuzner ML, Waxman SG. Sodium channels contribute to microglia/macrophage activation and function in EAE and MS. Glia. 49: 220-9. PMID 15390090 DOI: 10.1002/glia.20112  1
2004 Gwak YS, Hains BC, Johnson KM, Hulsebosch CE. Effect of age at time of spinal cord injury on behavioral outcomes in rat. Journal of Neurotrauma. 21: 983-93. PMID 15318998 DOI: 10.1089/0897715041650999  1
2004 Hains BC, Saab CY, Lo AC, Waxman SG. Sodium channel blockade with phenytoin protects spinal cord axons, enhances axonal conduction, and improves functional motor recovery after contusion SCI. Experimental Neurology. 188: 365-77. PMID 15246836 DOI: 10.1016/j.expneurol.2004.04.001  1
2004 Gwak YS, Hains BC, Johnson KM, Hulsebosch CE. Locomotor recovery and mechanical hyperalgesia following spinal cord injury depend on age at time of injury in rat. Neuroscience Letters. 362: 232-5. PMID 15158021 DOI: 10.1016/j.neulet.2004.03.019  1
2004 Hains BC, Saab CY, Klein JP, Craner MJ, Waxman SG. Altered sodium channel expression in second-order spinal sensory neurons contributes to pain after peripheral nerve injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 4832-9. PMID 15152043 DOI: 10.1523/JNEUROSCI.0300-04.2004  1
2004 Klein JP, Hains BC, Craner MJ, Black JA, Waxman SG. Apoptosis of vasopressinergic hypothalamic neurons in chronic diabetes mellitus. Neurobiology of Disease. 15: 221-8. PMID 15006692 DOI: 10.1016/j.nbd.2003.10.009  1
2004 Craner MJ, Hains BC, Lo AC, Black JA, Waxman SG. Co-localization of sodium channel Nav1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE. Brain : a Journal of Neurology. 127: 294-303. PMID 14662515 DOI: 10.1093/brain/awh032  1
2003 Hains BC, Klein JP, Saab CY, Craner MJ, Black JA, Waxman SG. Upregulation of sodium channel Nav1.3 and functional involvement in neuronal hyperexcitability associated with central neuropathic pain after spinal cord injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8881-92. PMID 14523090  1
2003 Hains BC, Black JA, Waxman SG. Primary cortical motor neurons undergo apoptosis after axotomizing spinal cord injury. The Journal of Comparative Neurology. 462: 328-41. PMID 12794736 DOI: 10.1002/cne.10733  1
2003 Hains BC, Willis WD, Hulsebosch CE. Temporal plasticity of dorsal horn somatosensory neurons after acute and chronic spinal cord hemisection in rat. Brain Research. 970: 238-41. PMID 12706267 DOI: 10.1016/S0006-8993(03)02347-3  1
2003 Hains BC, Johnson KM, Eaton MJ, Willis WD, Hulsebosch CE. Serotonergic neural precursor cell grafts attenuate bilateral hyperexcitability of dorsal horn neurons after spinal hemisection in rat. Neuroscience. 116: 1097-110. PMID 12617951 DOI: 10.1016/S0306-4522(02)00729-7  1
2003 Hains BC, Willis WD, Hulsebosch CE. Serotonin receptors 5-HT1A and 5-HT3 reduce hyperexcitability of dorsal horn neurons after chronic spinal cord hemisection injury in rat. Experimental Brain Research. 149: 174-86. PMID 12610685 DOI: 10.1007/s00221-002-1352-x  1
2002 Hains BC, Black JA, Waxman SG. Primary motor neurons fail to up-regulate voltage-gated sodium channel Na(v)1.3/brain type III following axotomy resulting from spinal cord injury. Journal of Neuroscience Research. 70: 546-52. PMID 12404508 DOI: 10.1002/jnr.10402  1
2002 Hains BC, Everhart AW, Fullwood SD, Hulsebosch CE. Changes in serotonin, serotonin transporter expression and serotonin denervation supersensitivity: involvement in chronic central pain after spinal hemisection in the rat. Experimental Neurology. 175: 347-62. PMID 12061865 DOI: 10.1006/exnr.2002.7892  1
2002 Hains BC, Yucra JA, Eaton MJ, Hulsebosch CE. Intralesion transplantation of serotonergic precursors enhances locomotor recovery but has no effect on development of chronic central pain following hemisection injury in rats. Neuroscience Letters. 324: 222-6. PMID 12009528 DOI: 10.1016/S0304-3940(02)00194-5  1
2002 Hains BC, Willis WD, Hulsebosch CE. Differential electrophysiological effects of brain-derived neurotrophic factor on dorsal horn neurons following chronic spinal cord hemisection injury in the rat. Neuroscience Letters. 320: 125-8. PMID 11852178 DOI: 10.1016/S0304-3940(02)00026-5  1
2001 Hains BC, Johnson KM, McAdoo DJ, Eaton MJ, Hulsebosch CE. Engraftment of serotonergic precursors enhances locomotor function and attenuates chronic central pain behavior following spinal hemisection injury in the rat. Experimental Neurology. 171: 361-78. PMID 11573989 DOI: 10.1006/exnr.2001.7751  1
2001 Hains BC, Fullwood SD, Eaton MJ, Hulsebosch CE. Subdural engraftment of serotonergic neurons following spinal hemisection restores spinal serotonin, downregulates serotonin transporter, and increases BDNF tissue content in rat. Brain Research. 913: 35-46. PMID 11532245 DOI: 10.1016/S0006-8993(01)02749-4  1
2001 Mills CD, Hains BC, Johnson KM, Hulsebosch CE. Strain and model differences in behavioral outcomes after spinal cord injury in rat. Journal of Neurotrauma. 18: 743-56. PMID 11526981 DOI: 10.1089/089771501316919111  1
2001 Hains BC, Yucra JA, Hulsebosch CE. Reduction of pathological and behavioral deficits following spinal cord contusion injury with the selective cyclooxygenase-2 inhibitor NS-398. Journal of Neurotrauma. 18: 409-23. PMID 11336442 DOI: 10.1089/089771501750170994  1
2000 Hulsebosch CE, Hains BC, Waldrep K, Young W. Bridging the gap: from discovery to clinical trials in spinal cord injury. Journal of Neurotrauma. 17: 1117-28. PMID 11186226  1
2000 Hains BC, Chastain KM, Everhart AW, McAdoo DJ, Hulsebosch CE. Transplants of adrenal medullary chromaffin cells reduce forelimb and hindlimb allodynia in a rodent model of chronic central pain after spinal cord hemisection injury. Experimental Neurology. 164: 426-37. PMID 10915581 DOI: 10.1006/exnr.2000.7439  1
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