Maxence V Nachury - Publications

Affiliations: 
2008- Molecular and Cellular Physiology Stanford University School of Medicine, Palo Alto, CA, United States 
Area:
Primary cilia
Website:
http://nachurylab.weebly.com

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Yang S, Bahl K, Chou HT, Woodsmith J, Stelzl U, Walz T, Nachury MV. Near-atomic structures of the BBSome reveal the basis for BBSome activation and binding to GPCR cargoes. Elife. 9. PMID 32510327 DOI: 10.7554/Elife.55954  0.382
2019 Chou HT, Apelt L, Farrell DP, White SR, Woodsmith J, Svetlov V, Goldstein JS, Nager AR, Li Z, Muller J, Dollfus H, Nudler E, Stelzl U, DiMaio F, Nachury MV, et al. The Molecular Architecture of Native BBSome Obtained by an Integrated Structural Approach. Structure (London, England : 1993). PMID 31303482 DOI: 10.1016/J.Str.2019.06.006  0.364
2019 Nachury MV, Mick DU. Establishing and regulating the composition of cilia for signal transduction. Nature Reviews. Molecular Cell Biology. PMID 30948801 DOI: 10.1038/S41580-019-0116-4  0.399
2018 Nachury MV. The molecular machines that traffic signaling receptors into and out of cilia. Current Opinion in Cell Biology. 51: 124-131. PMID 29579578 DOI: 10.1016/J.Ceb.2018.03.004  0.41
2018 Ye F, Nager AR, Nachury MV. BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone. The Journal of Cell Biology. PMID 29483145 DOI: 10.1083/Jcb.201709041  0.384
2018 Breslow DK, Hoogendoorn S, Kopp AR, Morgens DW, Vu BK, Kennedy MC, Han K, Li A, Hess GT, Bassik MC, Chen JK, Nachury MV. A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Nature Genetics. PMID 29459677 DOI: 10.1038/S41588-018-0054-7  0.731
2017 Niwa S, Tao L, Lu SY, Liew GM, Feng W, Nachury MV, Shen K. BORC Regulates the Axonal Transport of Synaptic Vesicle Precursors by Activating ARL-8. Current Biology : Cb. PMID 28823680 DOI: 10.1016/J.Cub.2017.07.013  0.33
2017 Steinman JB, Santarossa CC, Miller RM, Yu LS, Serpinskaya AS, Furukawa H, Morimoto S, Tanaka Y, Nishitani M, Asano M, Zalyte R, Ondrus AE, Johnson AG, Ye F, Nachury MV, et al. Chemical structure-guided design of dynapyrazoles, potent cell-permeable dynein inhibitors with a unique mode of action. Elife. 6. PMID 28524820 DOI: 10.7554/Elife.25174  0.356
2017 Xu Z, Schaedel L, Portran D, Aguilar A, Gaillard J, Marinkovich MP, Théry M, Nachury MV. Microtubules acquire resistance from mechanical breakage through intralumenal acetylation. Science (New York, N.Y.). 356: 328-332. PMID 28428427 DOI: 10.1126/Science.Aai8764  0.345
2017 Portran D, Schaedel L, Xu Z, Théry M, Nachury MV. Tubulin acetylation protects long-lived microtubules against mechanical ageing. Nature Cell Biology. PMID 28250419 DOI: 10.1038/Ncb3481  0.365
2016 Nager AR, Goldstein JS, Herranz-Pérez V, Portran D, Ye F, Garcia-Verdugo JM, Nachury MV. An Actin Network Dispatches Ciliary GPCRs into Extracellular Vesicles to Modulate Signaling. Cell. PMID 28017328 DOI: 10.1016/J.Cell.2016.11.036  0.394
2016 Luca VC, Jude KM, Pierce NW, Nachury MV, Fischer S, Garcia KC. Abstract B068: Structural basis for Notch1 engagement of Delta-like 4 and Jagged1 Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-B068  0.329
2015 Langousis G, Shimogawa MM, Saada EA, Vashisht AA, Spreafico R, Nager AR, Barshop WD, Nachury MV, Wohlschlegel JA, Hill KL. Loss of the BBSome perturbs endocytic trafficking and disrupts virulence of Trypanosoma brucei. Proceedings of the National Academy of Sciences of the United States of America. PMID 26721397 DOI: 10.1073/Pnas.1518079113  0.404
2015 Mick DU, Rodrigues RB, Leib RD, Adams CM, Chien AS, Gygi SP, Nachury MV. Proteomics of Primary Cilia by Proximity Labeling. Developmental Cell. PMID 26585297 DOI: 10.1016/J.Devcel.2015.10.015  0.417
2015 See SK, Hoogendoorn S, Chung AH, Ye F, Steinman JB, Sakata-Kato T, Miller RM, Cupido T, Zalyte R, Carter AP, Nachury MV, Kapoor TM, Chen JK. Cytoplasmic Dynein Antagonists with Improved Potency and Isoform Selectivity. Acs Chemical Biology. PMID 26555042 DOI: 10.1021/Acschembio.5B00895  0.424
2015 Schaedel L, John K, Gaillard J, Nachury MV, Blanchoin L, Théry M. Microtubules self-repair in response to mechanical stress. Nature Materials. 14: 1156-63. PMID 26343914 DOI: 10.1038/Nmat4396  0.323
2015 Breslow DK, Nachury MV. Analysis of soluble protein entry into primary cilia using semipermeabilized cells. Methods in Cell Biology. 127: 203-21. PMID 25837393 DOI: 10.1016/Bs.Mcb.2014.12.006  0.772
2015 Luca VC, Jude KM, Pierce NW, Nachury MV, Fischer S, Garcia KC. Structural biology. Structural basis for Notch1 engagement of Delta-like 4. Science (New York, N.Y.). 347: 847-53. PMID 25700513 DOI: 10.1126/Science.1261093  0.322
2014 Liew GM, Ye F, Nager AR, Murphy JP, Lee JS, Aguiar M, Breslow DK, Gygi SP, Nachury MV. The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3. Developmental Cell. 31: 265-78. PMID 25443296 DOI: 10.1016/j.devcel.2014.09.004  0.764
2014 Mourão A, Nager AR, Nachury MV, Lorentzen E. Structural basis for membrane targeting of the BBSome by ARL6. Nature Structural & Molecular Biology. 21: 1035-41. PMID 25402481 DOI: 10.1038/Nsmb.2920  0.357
2014 Nachury MV. How do cilia organize signalling cascades? Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369. PMID 25047619 DOI: 10.1098/Rstb.2013.0465  0.382
2014 Thauvin-Robinet C, Lee JS, Lopez E, Herranz-Pérez V, Shida T, Franco B, Jego L, Ye F, Pasquier L, Loget P, Gigot N, Aral B, Lopes CA, St-Onge J, Bruel AL, ... ... Nachury MV, et al. The oral-facial-digital syndrome gene C2CD3 encodes a positive regulator of centriole elongation. Nature Genetics. 46: 905-11. PMID 24997988 DOI: 10.1038/Ng.3031  0.372
2014 Aguilar A, Becker L, Tedeschi T, Heller S, Iomini C, Nachury MV. Α-tubulin K40 acetylation is required for contact inhibition of proliferation and cell-substrate adhesion. Molecular Biology of the Cell. 25: 1854-66. PMID 24743598 DOI: 10.1091/Mbc.E13-10-0609  0.358
2014 Howes SC, Alushin GM, Shida T, Nachury MV, Nogales E. Effects of tubulin acetylation and tubulin acetyltransferase binding on microtubule structure. Molecular Biology of the Cell. 25: 257-66. PMID 24227885 DOI: 10.1091/Mbc.E13-07-0387  0.364
2014 Scheidecker S, Etard C, Pierce NW, Geoffroy V, Schaefer E, Muller J, Chennen K, Flori E, Pelletier V, Poch O, Marion V, Stoetzel C, Strähle U, Nachury MV, Dollfus H. Exome sequencing of Bardet-Biedl syndrome patient identifies a null mutation in the BBSome subunit BBIP1 (BBS18). Journal of Medical Genetics. 51: 132-6. PMID 24026985 DOI: 10.1136/Jmedgenet-2013-101785  0.326
2014 Nachury M. Movement of Signaling Receptors Inside Primary Cilia Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.099  0.472
2013 Breslow DK, Koslover EF, Seydel F, Spakowitz AJ, Nachury MV. An in vitro assay for entry into cilia reveals unique properties of the soluble diffusion barrier. The Journal of Cell Biology. 203: 129-47. PMID 24100294 DOI: 10.1083/Jcb.201212024  0.77
2013 Montagnac G, Meas-Yedid V, Irondelle M, Castro-Castro A, Franco M, Shida T, Nachury MV, Benmerah A, Olivo-Marin JC, Chavrier P. αTAT1 catalyses microtubule acetylation at clathrin-coated pits. Nature. 502: 567-70. PMID 24097348 DOI: 10.1038/Nature12571  0.36
2013 Ye F, Breslow DK, Koslover EF, Spakowitz AJ, Nelson WJ, Nachury MV. Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors. Elife. 2: e00654. PMID 23930224 DOI: 10.7554/Elife.00654  0.762
2013 Ye F, Breslow DK, Koslover EF, Spakowitz AJ, Nelson WJ, Nachury MV. Author response: Single molecule imaging reveals a major role for diffusion in the exploration of ciliary space by signaling receptors Elife. DOI: 10.7554/Elife.00654.025  0.724
2012 Friedmann DR, Aguilar A, Fan J, Nachury MV, Marmorstein R. Structure of the α-tubulin acetyltransferase, αTAT1, and implications for tubulin-specific acetylation. Proceedings of the National Academy of Sciences of the United States of America. 109: 19655-60. PMID 23071314 DOI: 10.1073/Pnas.1209357109  0.356
2011 Seo S, Zhang Q, Bugge K, Breslow DK, Searby CC, Nachury MV, Sheffield VC. A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and Smoothened. Plos Genetics. 7: e1002358. PMID 22072986 DOI: 10.1371/Journal.Pgen.1002358  0.765
2011 Breslow DK, Nachury MV. Primary cilia: how to keep the riff-raff in the plasma membrane. Current Biology : Cb. 21: R434-6. PMID 21640903 DOI: 10.1016/J.Cub.2011.04.039  0.743
2011 Westlake CJ, Baye LM, Nachury MV, Wright KJ, Ervin KE, Phu L, Chalouni C, Beck JS, Kirkpatrick DS, Slusarski DC, Sheffield VC, Scheller RH, Jackson PK. Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome. Proceedings of the National Academy of Sciences of the United States of America. 108: 2759-64. PMID 21273506 DOI: 10.1073/Pnas.1018823108  0.613
2010 Shida T, Cueva JG, Xu Z, Goodman MB, Nachury MV. The major alpha-tubulin K40 acetyltransferase alphaTAT1 promotes rapid ciliogenesis and efficient mechanosensation. Proceedings of the National Academy of Sciences of the United States of America. 107: 21517-22. PMID 21068373 DOI: 10.1073/Pnas.1013728107  0.365
2010 Jin H, White SR, Shida T, Schulz S, Aguiar M, Gygi SP, Bazan JF, Nachury MV. The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia. Cell. 141: 1208-19. PMID 20603001 DOI: 10.1016/J.Cell.2010.05.015  0.403
2010 Hu Q, Milenkovic L, Jin H, Scott MP, Nachury MV, Spiliotis ET, Nelson WJ. A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution. Science (New York, N.Y.). 329: 436-9. PMID 20558667 DOI: 10.1126/Science.1191054  0.433
2010 Seeley ES, Nachury MV. The perennial organelle: assembly and disassembly of the primary cilium. Journal of Cell Science. 123: 511-8. PMID 20144999 DOI: 10.1242/Jcs.061093  0.378
2010 Nachury MV, Seeley ES, Jin H. Trafficking to the ciliary membrane: how to get across the periciliary diffusion barrier? Annual Review of Cell and Developmental Biology. 26: 59-87. PMID 19575670 DOI: 10.1146/Annurev.Cellbio.042308.113337  0.465
2009 Seeley ES, Nachury MV. Constructing and deconstructing roles for the primary cilium in tissue architecture and cancer. Methods in Cell Biology. 94: 299-313. PMID 20362097 DOI: 10.1016/S0091-679X(08)94015-2  0.305
2008 Loktev AV, Zhang Q, Beck JS, Searby CC, Scheetz TE, Bazan JF, Slusarski DC, Sheffield VC, Jackson PK, Nachury MV. A BBSome subunit links ciliogenesis, microtubule stability, and acetylation. Developmental Cell. 15: 854-65. PMID 19081074 DOI: 10.1016/J.Devcel.2008.11.001  0.601
2008 Berdougo E, Nachury MV, Jackson PK, Jallepalli PV. The nucleolar phosphatase Cdc14B is dispensable for chromosome segregation and mitotic exit in human cells. Cell Cycle (Georgetown, Tex.). 7: 1184-90. PMID 18418058 DOI: 10.4161/Cc.7.9.5792  0.542
2008 Nachury MV. Tandem affinity purification of the BBSome, a critical regulator of Rab8 in ciliogenesis. Methods in Enzymology. 439: 501-13. PMID 18374185 DOI: 10.1016/S0076-6879(07)00434-X  0.417
2007 Ban KH, Torres JZ, Miller JJ, Mikhailov A, Nachury MV, Tung JJ, Rieder CL, Jackson PK. The END network couples spindle pole assembly to inhibition of the anaphase-promoting complex/cyclosome in early mitosis. Developmental Cell. 13: 29-42. PMID 17609108 DOI: 10.1016/J.Devcel.2007.04.017  0.716
2007 Nachury MV, Loktev AV, Zhang Q, Westlake CJ, Peränen J, Merdes A, Slusarski DC, Scheller RH, Bazan JF, Sheffield VC, Jackson PK. A core complex of BBS proteins cooperates with the GTPase Rab8 to promote ciliary membrane biogenesis. Cell. 129: 1201-13. PMID 17574030 DOI: 10.1016/J.Cell.2007.03.053  0.59
2006 Miller JJ, Summers MK, Hansen DV, Nachury MV, Lehman NL, Loktev A, Jackson PK. Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor. Genes & Development. 20: 2410-20. PMID 16921029 DOI: 10.1101/Gad.1454006  0.724
2005 Blower MD, Nachury M, Heald R, Weis K. A Rae1-containing ribonucleoprotein complex is required for mitotic spindle assembly. Cell. 121: 223-34. PMID 15851029 DOI: 10.1016/J.Cell.2005.02.016  0.749
2004 Kaiser BK, Nachury MV, Gardner BE, Jackson PK. Xenopus Cdc14 alpha/beta are localized to the nucleolus and centrosome and are required for embryonic cell division. Bmc Cell Biology. 5: 27. PMID 15251038 DOI: 10.1186/1471-2121-5-27  0.755
2001 Nachury MV, Maresca TJ, Salmon WC, Waterman-Storer CM, Heald R, Weis K. Importin beta is a mitotic target of the small GTPase Ran in spindle assembly. Cell. 104: 95-106. PMID 11163243 DOI: 10.1016/S0092-8674(01)00194-5  0.588
1999 Nachury MV, Weis K. The direction of transport through the nuclear pore can be inverted. Proceedings of the National Academy of Sciences of the United States of America. 96: 9622-7. PMID 10449743 DOI: 10.1073/Pnas.96.17.9622  0.578
1998 Nachury MV, Ryder UW, Lamond AI, Weis K. Cloning and characterization of hSRP1 gamma, a tissue-specific nuclear transport factor. Proceedings of the National Academy of Sciences of the United States of America. 95: 582-7. PMID 9435235 DOI: 10.1073/Pnas.95.2.582  0.649
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