Jakub Mieczkowski - Publications

Affiliations: 
Nencki Institute, Warsaw, Poland, Warszawa, mazowieckie, Poland 
Website:
www.jmieczkowski.pl

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Leszczynska KB, Freitas-Huhtamäki A, Jayaprakash C, Dzwigonska M, Vitorino FNL, Horth C, Wojnicki K, Gielniewski B, Szadkowska P, Kaza B, Nazarian J, Ciolkowski MK, Trubicka J, Grajkowska W, Garcia BA, ... ... Mieczkowski J, et al. H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in pediatric high-grade glioma cells. Cell Reports. 43: 113707. PMID 38306270 DOI: 10.1016/j.celrep.2024.113707  0.487
2023 Leszczynska KB, Dzwigonska M, Estephan H, Moehlenbrink J, Bowler E, Giaccia AJ, Mieczkowski J, Kaminska B, Hammond EM. Hypoxia-mediated regulation of DDX5 through decreased chromatin accessibility and post-translational targeting restricts R-loop accumulation. Molecular Oncology. PMID 37013907 DOI: 10.1002/1878-0261.13431  0.529
2023 Amin A, Kadam S, Mieczkowski J, Ahmed I, Bhat YA, Shah F, Tolstorukov MY, Kingston RE, Padinhateeri R, Wani AH. Disruption of polyhomeotic polymerization decreases nucleosome occupancy and alters genome accessibility. Life Science Alliance. 6. PMID 36849253 DOI: 10.26508/lsa.202201768  0.488
2022 Perdyan A, Lawrynowicz U, Horbacz M, Kaminska B, Mieczkowski J. Integration of single-cell RNA sequencing and spatial transcriptomics to reveal the glioblastoma heterogeneity. F1000research. 11: 1180. PMID 36875988 DOI: 10.12688/f1000research.126243.1  0.427
2021 Stępniak K, Machnicka MA, Mieczkowski J, Macioszek A, Wojtaś B, Gielniewski B, Poleszak K, Perycz M, Król SK, Guzik R, Dąbrowski MJ, Dramiński M, Jardanowska M, Grabowicz I, Dziedzic A, et al. Author Correction: Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas. Nature Communications. 12: 7218. PMID 34873182 DOI: 10.1038/s41467-021-27448-5  0.45
2021 Leszczynska KB, Jayaprakash C, Kaminska B, Mieczkowski J. Emerging Advances in Combinatorial Treatments of Epigenetically Altered Pediatric High-Grade H3K27M Gliomas. Frontiers in Genetics. 12: 742561. PMID 34646308 DOI: 10.3389/fgene.2021.742561  0.529
2021 Stępniak K, Machnicka MA, Mieczkowski J, Macioszek A, Wojtaś B, Gielniewski B, Poleszak K, Perycz M, Król SK, Guzik R, Dąbrowski MJ, Dramiński M, Jardanowska M, Grabowicz I, Dziedzic A, et al. Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas. Nature Communications. 12: 3621. PMID 34131149 DOI: 10.1038/s41467-021-23922-2  0.565
2021 Ochocka N, Segit P, Walentynowicz KA, Wojnicki K, Cyranowski S, Swatler J, Mieczkowski J, Kaminska B. Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages. Nature Communications. 12: 1151. PMID 33608526 DOI: 10.1038/s41467-021-21407-w  0.539
2020 Ciechomska IA, Gielniewski B, Wojtas B, Kaminska B, Mieczkowski J. EGFR/FOXO3a/BIM signaling pathway determines chemosensitivity of BMP4-differentiated glioma stem cells to temozolomide. Experimental & Molecular Medicine. PMID 32788653 DOI: 10.1038/S12276-020-0479-9  0.53
2019 Wylot B, Mieczkowski J, Niedziolka S, Kaminska B, Zawadzka M. Csf1 Deficiency Dysregulates Glial Responses to Demyelination and Disturbs CNS White Matter Remyelination. Cells. 9. PMID 31906095 DOI: 10.3390/Cells9010099  0.505
2019 Kulesza DW, Ramji K, Maleszewska M, Mieczkowski J, Dabrowski M, Chouaib S, Kaminska B. Search for novel STAT3-dependent genes reveals SERPINA3 as a new STAT3 target that regulates invasion of human melanoma cells. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 31278347 DOI: 10.1038/S41374-019-0288-8  0.609
2019 Walentynowicz K, Ochocka N, Segit P, Mieczkowski J, Wojtaś B, Gielniewski B, Kostyra K, Baluszek S, Kostkiewicz B, Kaminska B. TMIC-65. GLOBAL PROFILING OF IMMUNE RESPONSE OF MICROGLIA AND MACROPHAGES IN PRECLINICAL MODEL OF GLIOBLASTOMA. Neuro-Oncology. 21: vi262-vi262. DOI: 10.1093/Neuonc/Noz175.1099  0.589
2018 Ulanska-Poutanen J, Mieczkowski J, Zhao C, Konarzewska K, Kaza B, Pohl HB, Bugajski L, Kaminska B, Franklin RJ, Zawadzka M. Injury-induced perivascular niche supports alternative differentiation of adult rodent CNS progenitor cells. Elife. 7. PMID 30222103 DOI: 10.7554/Elife.30325  0.538
2018 Walentynowicz KA, Ochocka N, Pasierbinska M, Wojnicki K, Stepniak K, Mieczkowski J, Ciechomska IA, Kaminska B. In Search for Reliable Markers of Glioma-Induced Polarization of Microglia. Frontiers in Immunology. 9: 1329. PMID 29963047 DOI: 10.3389/Fimmu.2018.01329  0.604
2018 Ulanska-Poutanen J, Mieczkowski J, Zhao C, Konarzewska K, Kaza B, Pohl HB, Bugajski L, Kaminska B, Franklin RJ, Zawadzka M. Author response: Injury-induced perivascular niche supports alternative differentiation of adult rodent CNS progenitor cells Elife. DOI: 10.7554/Elife.30325.025  0.503
2018 Baluszek SP, Mieczkowski J, Kamińska B. P01.103 Molecular landscape of diffuse gliomas associated with seizures Neuro-Oncology. 20: iii254-iii255. DOI: 10.1093/Neuonc/Noy139.145  0.439
2017 Garofalo S, Porzia A, Mainiero F, Di Angelantonio S, Cortese B, Basilico B, Pagani F, Cignitti G, Chece G, Maggio R, Tremblay E, Savage J, Bisht K, Esposito V, Bernardini G, ... ... Mieczkowski J, et al. Environmental stimuli shape microglial plasticity in glioma. Elife. 6. PMID 29286001 DOI: 10.7554/Elife.33415  0.565
2017 Gieryng A, Pszczolkowska D, Bocian K, Dabrowski M, Rajan WD, Kloss M, Mieczkowski J, Kaminska B. Immune microenvironment of experimental rat C6 gliomas resembles human glioblastomas. Scientific Reports. 7: 17556. PMID 29242629 DOI: 10.1038/S41598-017-17752-W  0.547
2017 Mueller B, Mieczkowski J, Kundu S, Wang P, Sadreyev R, Tolstorukov MY, Kingston RE. Widespread changes in nucleosome accessibility without changes in nucleosome occupancy during a rapid transcriptional induction. Genes & Development. PMID 28356342 DOI: 10.1101/Gad.293118.116  0.576
2016 Wang X, Lee RS, Alver BH, Haswell JR, Wang S, Mieczkowski J, Drier Y, Gillespie SM, Archer TC, Wu JN, Tzvetkov EP, Troisi EC, Pomeroy SL, Biegel JA, Tolstorukov MY, et al. SMARCB1-mediated SWI/SNF complex function is essential for enhancer regulation. Nature Genetics. PMID 27941797 DOI: 10.1038/Ng.3746  0.42
2016 Deaton AM, Gómez-Rodríguez M, Mieczkowski J, Tolstorukov MY, Kundu S, Sadreyev RI, Jansen LE, Kingston RE. Enhancer regions show high histone H3.3 turnover that changes during differentiation. Elife. 5. PMID 27304074 DOI: 10.7554/Elife.15316  0.565
2016 Mieczkowski J, Cook A, Bowman SK, Mueller B, Alver BH, Kundu S, Deaton AM, Urban JA, Larschan E, Park PJ, Kingston RE, Tolstorukov MY. MNase titration reveals differences between nucleosome occupancy and chromatin accessibility. Nature Communications. 7: 11485. PMID 27151365 DOI: 10.1038/Ncomms11485  0.561
2016 Deaton AM, Gómez-Rodríguez M, Mieczkowski J, Tolstorukov MY, Kundu S, Sadreyev RI, Jansen LE, Kingston RE. Author response: Enhancer regions show high histone H3.3 turnover that changes during differentiation Elife. DOI: 10.7554/Elife.15316.042  0.542
2015 Mieczkowski J, Kocyk M, Nauman P, Gabrusiewicz K, Sielska M, Przanowski P, Maleszewska M, Rajan WD, Pszczolkowska D, Tykocki T, Grajkowska W, Kotulska K, Roszkowski M, Kostkiewicz B, Kaminska B. Down-regulation of IKKβ expression in glioma-infiltrating microglia/macrophages is associated with defective inflammatory/immune gene responses in glioblastoma. Oncotarget. 6: 33077-90. PMID 26427514 DOI: 10.18632/Oncotarget.5310  0.583
2014 Kruczyk M, Przanowski P, Dabrowski M, Swiatek-Machado K, Mieczkowski J, Wallerman O, Ronowicz A, Piotrowski A, Wadelius C, Kaminska B, Komorowski J. Integration of genome-wide of Stat3 binding and epigenetic modification mapping with transcriptome reveals novel Stat3 target genes in glioma cells. Biochimica Et Biophysica Acta. 1839: 1341-50. PMID 25111868 DOI: 10.1016/J.Bbagrm.2014.07.010  0.624
2014 Przanowski P, Dabrowski M, Ellert-Miklaszewska A, Kloss M, Mieczkowski J, Kaza B, Ronowicz A, Hu F, Piotrowski A, Kettenmann H, Komorowski J, Kaminska B. The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia. Journal of Molecular Medicine (Berlin, Germany). 92: 239-54. PMID 24097101 DOI: 10.1007/S00109-013-1090-5  0.587
2012 Mieczkowski J, Swiatek-Machado K, Kaminska B. Identification of pathway deregulation--gene expression based analysis of consistent signal transduction. Plos One. 7: e41541. PMID 22848524 DOI: 10.1371/Journal.Pone.0041541  0.539
2012 Swiatek-Machado K, Mieczkowski J, Ellert-Miklaszewska A, Swierk P, Fokt I, Szymanski S, Skora S, Szeja W, Grynkiewicz G, Lesyng B, Priebe W, Kaminska B. Novel small molecular inhibitors disrupt the JAK/STAT3 and FAK signaling pathways and exhibit a potent antitumor activity in glioma cells. Cancer Biology & Therapy. 13: 657-70. PMID 22555804 DOI: 10.4161/Cbt.20083  0.589
2011 Swiatek-Machado KE, Dabrowski M, Mieczkowski J, Przanowski P, Adach-Kilon A, Kaminska B. Abstract C100: Towards better understanding a role of STAT3 in glioma pathology: Identification of novel transcriptional targets of STAT3. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C100  0.624
2010 Dabrowski M, Dojer N, Zawadzka M, Mieczkowski J, Kaminska B. Comparative analysis of cis-regulation following stroke and seizures in subspaces of conserved eigensystems. Bmc Systems Biology. 4: 86. PMID 20565733 DOI: 10.1186/1752-0509-4-86  0.55
2010 Mieczkowski J, Tyburczy ME, Dabrowski M, Pokarowski P. Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements. Bmc Bioinformatics. 11: 104. PMID 20181266 DOI: 10.1186/1471-2105-11-104  0.301
2010 Tyburczy ME, Kotulska K, Pokarowski P, Mieczkowski J, Kucharska J, Grajkowska W, Roszkowski M, Jozwiak S, Kaminska B. Novel proteins regulated by mTOR in subependymal giant cell astrocytomas of patients with tuberous sclerosis complex and new therapeutic implications. The American Journal of Pathology. 176: 1878-90. PMID 20133820 DOI: 10.2353/Ajpath.2010.090950  0.611
2010 Tyburczy ME, Kotulska K, Pokarowski P, Mieczkowski J, Grajkowska W, Jozwiak S, Kaminska B. Abstract 4353: Identification of proteins regulated by mTOR in brain tumors of patients with tuberous sclerosis complex Cancer Research. 70: 4353-4353. DOI: 10.1158/1538-7445.Am10-4353  0.615
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