Luis G. Cuello, Ph.D. - Publications

Affiliations: 
2005 University of Virginia, Charlottesville, VA 
Area:
General Biophysics, Animal Physiology Biology

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Coonen L, Mayeur E, De Neuter N, Snyders DJ, Cuello LG, Labro AJ. The Selectivity Filter Is Involved in the U-Type Inactivation Process of Kv2.1 and Kv3.1 Channels. Biophysical Journal. PMID 32365329 DOI: 10.1016/J.Bpj.2020.03.032  0.4
2019 Tilegenova C, Cortes DM, Jahovic N, Hardy E, Hariharan P, Guan L, Cuello LG. Structure, function, and ion-binding properties of a K channel stabilized in the 2,4-ion-bound configuration. Proceedings of the National Academy of Sciences of the United States of America. PMID 31387976 DOI: 10.1073/Pnas.1901888116  0.96
2018 Labro AJ, Cortes DM, Tilegenova C, Cuello LG. Inverted allosteric coupling between activation and inactivation gates in K channels. Proceedings of the National Academy of Sciences of the United States of America. PMID 29735651 DOI: 10.1073/Pnas.1800559115  0.96
2018 Tilegenova C, Elberson BW, Marien Cortes D, Cuello LG. CW-EPR Spectroscopy and Site-Directed Spin Labeling to Study the Structural Dynamics of Ion Channels. Methods in Molecular Biology (Clifton, N.J.). 1684: 279-288. PMID 29058199 DOI: 10.1007/978-1-4939-7362-0_21  0.88
2017 Cuello LG, Cortes DM, Perozo E. The gating cycle of a K(+) channel at atomic resolution. Elife. 6. PMID 29165243 DOI: 10.7554/Elife.28032  0.96
2017 Elberson BW, Whisenant TE, Cortes DM, Cuello LG. A cost-effective protocol for the over-expression and purification of fully-functional and more stable Erwinia chrysanthemi ligand-gated ion channel. Protein Expression and Purification. 133: 177-186. PMID 28279818 DOI: 10.1016/J.Pep.2017.03.006  0.96
2017 Tilegenova C, Cortes DM, Cuello LG. Hysteresis of KcsA potassium channel's activation- deactivation gating is caused by structural changes at the channel's selectivity filter. Proceedings of the National Academy of Sciences of the United States of America. 114: 3234-3239. PMID 28265056 DOI: 10.1073/Pnas.1618101114  0.96
2016 Krishnan S, Fiori MC, Whisenant TE, Cortes DM, Altenberg GA, Cuello LG. An Escherichia coli-Based Assay to Assess the Function of Recombinant Human Hemichannels. Journal of Biomolecular Screening. PMID 27789753 DOI: 10.1177/1087057116675321  0.96
2016 Tilegenova C, Vemulapally S, Cortes DM, Cuello LG. An improved method for the cost-effective expression and purification of large quantities of KcsA. Protein Expression and Purification. 127: 53-60. PMID 27393071 DOI: 10.1016/J.Pep.2016.07.002  0.96
2016 Tilegenova C, Vemulapally S, Cortes DM, Cuello LG. An improved method for the cost-effective expression and purification of large quantities of KcsA Protein Expression and Purification. 127: 53-60. DOI: 10.1016/j.pep.2016.07.002  0.96
2015 Zhao R, Dai H, Mendelman N, Cuello LG, Chill JH, Goldstein SA. Designer and natural peptide toxin blockers of the KcsA potassium channel identified by phage display. Proceedings of the National Academy of Sciences of the United States of America. PMID 26627718 DOI: 10.1073/Pnas.1514728112  0.96
2015 Morera FJ, Saravia J, Pontigo JP, Vargas-Chacoff L, Contreras GF, Pupo A, Lorenzo Y, Castillo K, Tilegenova C, Cuello LG, Gonzalez C. Voltage-dependent BK and Hv1 channels expressed in non-excitable tissues: New therapeutics opportunities as targets in human diseases. Pharmacological Research. PMID 26305431 DOI: 10.1016/J.Phrs.2015.08.011  0.96
2015 Fiori MC, Krishnan S, Cortes DM, Retamal MA, Reuss L, Altenberg GA, Cuello LG. Functional hemichannels formed by human connexin 26 expressed in bacteria. Bioscience Reports. 35. PMID 25585383 DOI: 10.1042/Bsr20140089  0.96
2014 Fiori MC, Reuss L, Cuello LG, Altenberg GA. Functional analysis and regulation of purified connexin hemichannels. Frontiers in Physiology. 5: 71. PMID 24611052 DOI: 10.3389/Fphys.2014.00071  0.96
2014 Randich AM, Cuello LG, Wanderling SS, Perozo E. Biochemical and structural analysis of the hyperpolarization-activated K(+) channel MVP. Biochemistry. 53: 1627-36. PMID 24490868 DOI: 10.1021/Bi4014243  0.96
2013 Gonzalez-Gutierrez G, Cuello LG, Nair SK, Grosman C. Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography. Proceedings of the National Academy of Sciences of the United States of America. 110: 18716-21. PMID 24167270 DOI: 10.1073/Pnas.1313156110  0.96
2011 Pan AC, Cuello LG, Perozo E, Roux B. Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations. The Journal of General Physiology. 138: 571-80. PMID 22124115 DOI: 10.1085/Jgp.201110670  0.96
2011 Uysal S, Cuello LG, Cortes DM, Koide S, Kossiakoff AA, Perozo E. Mechanism of activation gating in the full-length KcsA K+ channel. Proceedings of the National Academy of Sciences of the United States of America. 108: 11896-9. PMID 21730186 DOI: 10.1073/Pnas.1105112108  0.96
2010 Dalmas O, Cuello LG, Jogini V, Cortes DM, Roux B, Perozo E. Structural dynamics of the magnesium-bound conformation of CorA in a lipid bilayer. Structure (London, England : 1993). 18: 868-78. PMID 20637423 DOI: 10.1016/J.Str.2010.04.009  0.96
2010 Cuello LG, Jogini V, Cortes DM, Pan AC, Gagnon DG, Dalmas O, Cordero-Morales JF, Chakrapani S, Roux B, Perozo E. Structural basis for the coupling between activation and inactivation gates in K(+) channels. Nature. 466: 272-5. PMID 20613845 DOI: 10.1038/Nature09136  0.96
2010 Cuello LG, Jogini V, Cortes DM, Perozo E. Structural mechanism of C-type inactivation in K(+) channels. Nature. 466: 203-8. PMID 20613835 DOI: 10.1038/Nature09153  0.96
2010 Cuello LG, Jogini V, Cortes DM, Sompornpisut A, Purdy MD, Wiener MC, Perozo E. Design and characterization of a constitutively open KcsA. Febs Letters. 584: 1133-8. PMID 20153331 DOI: 10.1016/J.Febslet.2010.02.015  0.96
2010 Cuello LG, Cortes DM, Jogini V, Sompornpisut A, Perozo E. A molecular mechanism for proton-dependent gating in KcsA. Febs Letters. 584: 1126-32. PMID 20138880 DOI: 10.1016/J.Febslet.2010.02.003  0.96
2009 Takacs Z, Toups M, Kollewe A, Johnson E, Cuello LG, Driessens G, Biancalana M, Koide A, Ponte CG, Perozo E, Gajewski TF, Suarez-Kurtz G, Koide S, Goldstein SA. A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library. Proceedings of the National Academy of Sciences of the United States of America. 106: 22211-6. PMID 20007782 DOI: 10.1073/Pnas.0910123106  0.96
2008 Chakrapani S, Cuello LG, Cortes DM, Perozo E. Structural dynamics of an isolated voltage-sensor domain in a lipid bilayer. Structure (London, England : 1993). 16: 398-409. PMID 18334215 DOI: 10.1016/J.Str.2007.12.015  0.96
2006 Blunck R, Cordero-Morales JF, Cuello LG, Perozo E, Bezanilla F. Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction. The Journal of General Physiology. 128: 569-81. PMID 17043150 DOI: 10.1085/Jgp.200609638  0.96
2006 Cordero-Morales JF, Cuello LG, Zhao Y, Jogini V, Cortes DM, Roux B, Perozo E. Molecular determinants of gating at the potassium-channel selectivity filter. Nature Structural & Molecular Biology. 13: 311-8. PMID 16532009 DOI: 10.1038/Nsmb1069  0.96
2006 Cordero-Morales JF, Cuello LG, Perozo E. Voltage-dependent gating at the KcsA selectivity filter. Nature Structural & Molecular Biology. 13: 319-22. PMID 16532008 DOI: 10.1038/Nsmb1070  0.96
2005 Ptak CP, Cuello LG, Perozo E. Electrostatic interaction of a K+ channel RCK domain with charged membrane surfaces. Biochemistry. 44: 62-71. PMID 15628846 DOI: 10.1021/Bi048390F  0.96
2004 Cuello LG, Cortes DM, Perozo E. Molecular architecture of the KvAP voltage-dependent K+ channel in a lipid bilayer. Science (New York, N.Y.). 306: 491-5. PMID 15486302 DOI: 10.1126/Science.1101373  0.96
2002 Perozo E, Cuello LG, Cortes DM, Liu YS, Sompornpisut P. EPR approaches to ion channel structure and function. Novartis Foundation Symposium. 245: 146-58; discussion 1. PMID 12027005 DOI: 10.1002/0470868759.Ch10  0.96
2001 Cortes DM, Cuello LG, Perozo E. Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating. The Journal of General Physiology. 117: 165-80. PMID 11158168 DOI: 10.1085/Jgp.117.2.165  0.96
1999 Perozo E, Cortes DM, Cuello LG. Structural rearrangements underlying K+-channel activation gating. Science (New York, N.Y.). 285: 73-8. PMID 10390363 DOI: 10.1126/Science.285.5424.73  0.96
1998 Perozo E, Cortes DM, Cuello LG. Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy. Nature Structural Biology. 5: 459-69. PMID 9628484 DOI: 10.1038/Nsb0698-459  0.96
1998 Cuello LG, Romero JG, Cortes DM, Perozo E. pH-dependent gating in the Streptomyces lividans K+ channel. Biochemistry. 37: 3229-36. PMID 9536962 DOI: 10.1021/Bi972997X  0.96
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