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Nicola J. Tolliday, Ph.D. - Publications

Affiliations: 
2002 Harvard University, Cambridge, MA, United States 
Area:
Cell Biology
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39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Sykes DB, Kfoury YS, Mercier FE, Wawer MJ, Law JM, Haynes MK, Lewis TA, Schajnovitz A, Jain E, Lee D, Meyer H, Pierce KA, Tolliday NJ, Waller A, Ferrara SJ, et al. Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia. Cell. PMID 27641501 DOI: 10.1016/J.Cell.2016.08.057  0.396
2015 de Waal L, Lewis TA, Rees MG, Tsherniak A, Wu X, Choi PS, Gechijian L, Hartigan C, Faloon PW, Hickey MJ, Tolliday N, Carr SA, Clemons PA, Munoz B, Wagner BK, et al. Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics. Nature Chemical Biology. PMID 26656089 DOI: 10.1038/Nchembio.1984  0.423
2015 Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X, Tolliday NJ, Golub TR, Carr SA, Shamji AF, Stern AM, Mandinova A, Schreiber SL, Lee SW. Corrigendum: Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature. PMID 26375002 DOI: 10.1038/Nature15370  0.31
2015 Chattopadhyay S, Stewart AL, Mukherjee S, Huang C, Hartwell KA, Miller PG, Subramanian R, Carmody LC, Yusuf RZ, Sykes DB, Paulk J, Vetere A, Vallet S, Santo L, Cirstea DD, ... ... Tolliday NJ, et al. Niche-Based Screening in Multiple Myeloma Identifies a Kinesin-5 Inhibitor with Improved Selectivity over Hematopoietic Progenitors. Cell Reports. PMID 25660025 DOI: 10.1016/J.Celrep.2015.01.017  0.438
2015 Waal Ld, Lewis TA, Rees MG, Tsherniak A, Wu X, Choi PS, Gechijian L, Hartigan C, Faloon PW, Hickey MJ, Tolliday N, Carr SA, Clemons PA, Munoz B, Wagner BK, et al. Abstract C136: Identification of selective cancer cytotoxic modulators of phosphodiesterase 3a by predictive chemogenomics Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-C136  0.394
2014 Kawasumi M, Bradner JE, Tolliday N, Thibodeau R, Sloan H, Brummond KM, Nghiem P. Identification of ATR-Chk1 pathway inhibitors that selectively target p53-deficient cells without directly suppressing ATR catalytic activity. Cancer Research. 74: 7534-45. PMID 25336189 DOI: 10.1158/0008-5472.Can-14-2650  0.41
2014 Lee Y, Dominy JE, Choi YJ, Jurczak M, Tolliday N, Camporez JP, Chim H, Lim JH, Ruan HB, Yang X, Vazquez F, Sicinski P, Shulman GI, Puigserver P. Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression. Nature. 510: 547-51. PMID 24870244 DOI: 10.1038/Nature13267  0.302
2014 Gutierrez A, Pan L, Groen RWJ, Baleydier F, Kentsis A, Marineau J, Grebliunaite R, Kozakewich E, Reed C, Pflumio F, Poglio S, Uzan B, Clemons P, VerPlank L, An F, ... ... Tolliday N, et al. Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia Journal of Clinical Investigation. 124: 644-655. PMID 24401270 DOI: 10.1172/Jci65093  0.415
2014 Gutierrez A, Pan L, Groen R, Baleydier F, Kentsis A, Marineau J, Grebliunaite R, Kozakewich E, Reed C, Pflumio F, Poglio S, Uzan B, Clemons P, Verplank L, An F, ... ... Tolliday N, et al. Abstract IA8: A new class of drugs active in T-ALL is revealed in a zebrafish screen Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-Ia8  0.421
2014 Waal LMd, Lewis TA, Gechijian L, Tsherniak A, Youngsaye W, Rees M, Mikse O, Hickey M, Faloon P, Tolliday N, Koehler A, Schenone M, Wong K, Shamji A, Munoz B, et al. Abstract 4596: An integrated genomic characterization of the target of a small molecule identifies a novel cancer dependency Cancer Research. 74: 4596-4596. DOI: 10.1158/1538-7445.Am2014-4596  0.447
2013 Yuan Y, Hartland K, Boskovic Z, Wang Y, Walpita D, Lysy PA, Zhong C, Young DW, Kim YK, Tolliday NJ, Sokal EM, Schreiber SL, Wagner BK. A small-molecule inducer of PDX1 expression identified by high-throughput screening. Chemistry & Biology. 20: 1513-22. PMID 24290880 DOI: 10.1016/J.Chembiol.2013.10.013  0.398
2013 Hartwell KA, Miller PG, Mukherjee S, Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M, Järås M, Puram R, Dancik V, Al-Shahrour F, Kindler T, Tothova Z, Chattopadhyay S, ... ... Tolliday NJ, et al. Niche-based screening identifies small-molecule inhibitors of leukemia stem cells. Nature Chemical Biology. 9: 840-8. PMID 24161946 DOI: 10.1038/Nchembio.1367  0.429
2013 Frumm SM, Fan ZP, Ross KN, Duvall JR, Gupta S, VerPlank L, Suh BC, Holson E, Wagner FF, Smith WB, Paranal RM, Bassil CF, Qi J, Roti G, Kung AL, ... ... Tolliday N, et al. Selective HDAC1/HDAC2 inhibitors induce neuroblastoma differentiation. Chemistry & Biology. 20: 713-25. PMID 23706636 DOI: 10.1016/J.Chembiol.2013.03.020  0.405
2013 Mulrooney CA, Lahr DL, Quintin MJ, Youngsaye W, Moccia D, Asiedu JK, Mulligan EL, Akella LB, Marcaurelle LA, Montgomery P, Bittker JA, Clemons PA, Brudz S, Dandapani S, Duvall JR, ... Tolliday NJ, et al. An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries. Journal of Computer-Aided Molecular Design. 27: 455-68. PMID 23585218 DOI: 10.1007/S10822-013-9641-Y  0.337
2013 Kawasumi M, Bradner JE, Tolliday N, Thibodeau R, Sloan H, Brummond KM, Nghiem P. Abstract B04: A chemical genetic screen identifies novel ATM/ATR pathway inhibitors that sensitize p53-deficient cells to DNA-damaging agents without affecting ATR kinase catalytic activity Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-B04  0.426
2012 Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, ... ... Tolliday NJ, et al. Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL. Cell. 150: 575-89. PMID 22863010 DOI: 10.1016/J.Cell.2012.06.032  0.447
2012 Dykhuizen EC, Carmody LC, Tolliday N, Crabtree GR, Palmer MA. Screening for inhibitors of an essential chromatin remodeler in mouse embryonic stem cells by monitoring transcriptional regulation. Journal of Biomolecular Screening. 17: 1221-30. PMID 22853929 DOI: 10.1177/1087057112455060  0.446
2012 Kitami T, Logan DJ, Negri J, Hasaka T, Tolliday NJ, Carpenter AE, Spiegelman BM, Mootha VK. A chemical screen probing the relationship between mitochondrial content and cell size. Plos One. 7: e33755. PMID 22479437 DOI: 10.1371/Journal.Pone.0033755  0.358
2012 Banerji V, Frumm SM, Ross KN, Li LS, Schinzel AC, Hahn CK, Kakoza RM, Chow KT, Ross L, Alexe G, Tolliday N, Inguilizian H, Galinsky I, Stone RM, DeAngelo DJ, et al. The intersection of genetic and chemical genomic screens identifies GSK-3α as a target in human acute myeloid leukemia. The Journal of Clinical Investigation. 122: 935-47. PMID 22326953 DOI: 10.1172/Jci46465  0.462
2012 Chattopadhyay S, Stewart AL, Mukherjee S, Huang C, Hartwell KA, Miller PG, Carmody L, Yusuf RZ, Sykes DB, Vallet S, Santo L, Cirstea DD, Hideshima T, Dancik V, Cheah J, ... ... Tolliday N, et al. Niche-Based Screening Identifies Novel Small Molecules That Overcome Stromal Effects in Multiple Myeloma Blood. 120: 571-571. DOI: 10.1182/Blood.V120.21.571.571  0.473
2012 Gutierrez A, Kentsis A, Pan L, Baleydier F, Marineau J, Grebliunaite R, Kozakewich E, Reed C, Pflumio F, Poglio S, Uzan B, Clemons PA, VerPlank L, An WF, Burbank J, ... ... Tolliday NJ, et al. Phenothiazines Induce Apoptosis in T-Cell Acute Lymphoblastic Leukemia by Activating the Phosphatase Activity of the PP2A Tumor Suppressor Blood. 120: 3558-3558. DOI: 10.1182/Blood.V120.21.3558.3558  0.411
2012 Sykes DB, Haynes MK, Tolliday N, Waller A, Cobert JM, Szekely BA, Hasaka TP, Sklar L, Zon LI, Scadden DT. Identifying Small Molecules That Overcome HoxA9-Mediated Differentiation Arrest in Acute Myeloid Leukemia Blood. 120: 3513-3513. DOI: 10.1182/Blood.V120.21.3513.3513  0.436
2011 Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X, Tolliday NJ, Golub TR, Carr SA, Shamji AF, Stern AM, Mandinova A, Schreiber SL, Lee SW. Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature. 475: 231-4. PMID 21753854 DOI: 10.1038/Nature10167  0.407
2011 Shaw AT, Winslow MM, Magendantz M, Ouyang C, Dowdle J, Subramanian A, Lewis TA, Maglathin RL, Tolliday N, Jacks T. Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress. Proceedings of the National Academy of Sciences of the United States of America. 108: 8773-8. PMID 21555567 DOI: 10.1073/Pnas.1105941108  0.34
2011 Hartwell KA, Miller PG, Stewart AL, Kahn AR, Logan DJ, Negri J, Duvet M, Chattopadhyay S, Shterental S, Chu LP, Shieh JH, Jaeraas M, Dancik V, Narayan R, Huang C, ... ... Tolliday NJ, et al. Niche-Based Screening Reveals Leukemia Stem Cell Specific Therapeutics Blood. 118: 760-760. DOI: 10.1182/Blood.V118.21.760.760  0.462
2011 Stegmaier K, Crompton B, Jessneck J, Ross K, Gupta S, Plank LV, Winckler W, Tolliday N. Abstract LB-240: Modulating transcription factor abnormalities in pediatric cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-240  0.45
2010 Tolliday N. High-Throughput Assessment of Mammalian Cell Viability by Determination of Adenosine Triphosphate Levels Current Protocols in Chemical Biology. 2: 153-161. PMID 23839967 DOI: 10.1002/9780470559277.Ch100045  0.371
2009 An WF, Tolliday N. Cell-based assays for high-throughput screening. Molecular Biotechnology. 45: 180-186. PMID 20151227 DOI: 10.1007/S12033-010-9251-Z  0.393
2009 An WF, Tolliday NJ. Introduction: cell-based assays for high-throughput screening. Methods in Molecular Biology (Clifton, N.J.). 486: 1-12. PMID 19347612 DOI: 10.1007/978-1-60327-545-3_1  0.346
2009 Ong SE, Schenone M, Margolin AA, Li X, Do K, Doud MK, Mani DR, Kuai L, Wang X, Wood JL, Tolliday NJ, Koehler AN, Marcaurelle LA, Golub TR, Gould RJ, et al. Identifying the proteins to which small-molecule probes and drugs bind in cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 4617-22. PMID 19255428 DOI: 10.1073/Pnas.0900191106  0.41
2009 Wen Q, Huang Z, Small S, Bubna N, An F, Bliss-Moreau M, Verplank L, Lewis T, Schenone M, Tolliday N, Moore C, Carpenter A, Mercher T, Levine RL, Izraeli S, et al. Identification of Inducers of Megakaryocyte Polyploidization and Their Use as Targeted Differentiation Therapy for Acute Megakaryocytic Leukemia. Blood. 114: 792-792. DOI: 10.1182/Blood.V114.22.792.792  0.459
2008 Zimmer M, Ebert BL, Neil C, Brenner K, Papaioannou I, Melas A, Tolliday N, Lamb J, Pantopoulos K, Golub T, Iliopoulos O. Small-molecule inhibitors of HIF-2a translation link its 5'UTR iron-responsive element to oxygen sensing. Molecular Cell. 32: 838-48. PMID 19111663 DOI: 10.1016/J.Molcel.2008.12.004  0.318
2008 Seiler KP, George GA, Happ MP, Bodycombe NE, Carrinski HA, Norton S, Brudz S, Sullivan JP, Muhlich J, Serrano M, Ferraiolo P, Tolliday NJ, Schreiber SL, Clemons PA. ChemBank: a small-molecule screening and cheminformatics resource database. Nucleic Acids Research. 36: D351-9. PMID 17947324 DOI: 10.1093/Nar/Gkm843  0.386
2006 Tolliday N, Clemons PA, Ferraiolo P, Koehler AN, Lewis TA, Li X, Schreiber SL, Gerhard DS, Eliasof S. Small molecules, big players: the National Cancer Institute's Initiative for Chemical Genetics. Cancer Research. 66: 8935-42. PMID 16982730 DOI: 10.1158/0008-5472.Can-06-2552  0.355
2006 Lister IM, Tolliday NJ, Li R. Characterization of the minimum domain required for targeting budding yeast myosin II to the site of cell division. Bmc Biology. 4: 19. PMID 16800887 DOI: 10.1186/1741-7007-4-19  0.404
2005 Ebert BL, Mak R, Pretz JL, Peck D, Haggerty S, Tolliday N, Golub TR. High Throughput Screen To Identify Small Molecules That Differentially Regulate Expression of the Globin Genes. Blood. 106: 3632-3632. DOI: 10.1182/Blood.V106.11.3632.3632  0.395
2003 Tolliday N, Pitcher M, Li R. Direct evidence for a critical role of myosin II in budding yeast cytokinesis and the evolvability of new cytokinetic mechanisms in the absence of myosin II. Molecular Biology of the Cell. 14: 798-809. PMID 12589071 DOI: 10.1091/Mbc.E02-09-0558  0.384
2003 Tolliday N, VerPlank L, Li R. Rho1 directs formin-mediated actin ring assembly during budding yeast cytokinesis. Current Biology : Cb. 12: 1864-70. PMID 12419188 DOI: 10.1016/S0960-9822(02)01238-1  0.357
2001 Tolliday N, Bouquin N, Li R. Assembly and regulation of the cytokinetic apparatus in budding yeast Current Opinion in Microbiology. 4: 690-695. PMID 11731321 DOI: 10.1016/S1369-5274(01)00270-3  0.369
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