Megan L. O'Mara - Publications

Affiliations: 
Australian National University, Acton, Australian Capital Territory, Australia 

28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Frangos ZJ, Wilson KA, Aitken HM, Cantwell Chater R, Vandenberg RJ, O'Mara ML. Membrane cholesterol regulates inhibition and substrate transport by the glycine transporter, GlyT2. Life Science Alliance. 6. PMID 36690444 DOI: 10.26508/lsa.202201708  0.316
2021 Fairweather SJ, Gupta V, Chitsaz M, Booth L, Brown MH, O'Mara ML. Coordination of Substrate Binding and Protonation in the MtrD Efflux Pump Controls the Functionally Rotating Transport Mechanism. Acs Infectious Diseases. PMID 33980014 DOI: 10.1021/acsinfecdis.1c00149  0.306
2020 Carey Hulyer AR, Briggs DA, O'Mara ML, Kerr ID, Harmer JR, Callaghan R. Cross-linking, DEER-spectroscopy and molecular dynamics confirm the inward facing state of P-glycoprotein in a lipid membrane. Journal of Structural Biology. 107513. PMID 32339763 DOI: 10.1016/J.Jsb.2020.107513  0.414
2019 Mostyn SN, Wilson KA, Schumann-Gillett A, Frangos ZJ, Shimmon S, Rawling T, Ryan RM, O'Mara ML, Vandenberg RJ. Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics. Elife. 8. PMID 31621581 DOI: 10.7554/Elife.47150  0.382
2019 Chiou TT, Long P, Schumann-Gillett A, Kanamarlapudi V, Haas SA, Harvey K, O'Mara ML, De Blas AL, Kalscheuer VM, Harvey RJ. Mutation p.R356Q in the Collybistin Phosphoinositide Binding Site Is Associated With Mild Intellectual Disability. Frontiers in Molecular Neuroscience. 12: 60. PMID 30914922 DOI: 10.3389/Fnmol.2019.00060  0.323
2019 Mostyn SN, Wilson KA, Schumann-Gillett A, Frangos ZJ, Shimmon S, Rawling T, Ryan RM, O'Mara ML, Vandenberg RJ. Author response: Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics Elife. DOI: 10.7554/Elife.47150.029  0.384
2017 Carland JE, Thomas M, Mostyn SN, Subramanian N, O'Mara ML, Ryan RM, Vandenberg RJ. Molecular Determinants for Substrate Interactions with the Glycine Transporter GlyT2. Acs Chemical Neuroscience. PMID 29120604 DOI: 10.1021/Acschemneuro.7B00407  0.422
2017 Anandan A, Evans GL, Condic-Jurkic K, O'Mara ML, John CM, Phillips NJ, Jarvis GA, Wills SS, Stubbs KA, Moraes I, Kahler CM, Vrielink A. Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding. Proceedings of the National Academy of Sciences of the United States of America. PMID 28193899 DOI: 10.1073/Pnas.1612927114  0.301
2016 Mittra R, Pavy M, Subramanian N, George AM, O'Mara ML, Kerr ID, Callaghan R. Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein. Biochemical Pharmacology. PMID 27729218 DOI: 10.1016/J.Bcp.2016.10.002  0.392
2016 Subramanian N, Scopelliti AJ, Carland JE, Ryan RM, O'Mara ML, Vandenberg RJ. Correction: Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2. Plos One. 11: e0159896. PMID 27434127 DOI: 10.1371/Journal.Pone.0159896  0.34
2015 Subramanian N, Schumann-Gillett A, Mark AE, O'Mara ML. Understanding the accumulation of P-glycoprotein substrates within cells: The effect of cholesterol on membrane partitioning. Biochimica Et Biophysica Acta. PMID 26724201 DOI: 10.1016/J.Bbamem.2015.12.025  0.345
2015 Deplazes E, Begg SL, van Wonderen JH, Campbell R, Kobe B, Paton JC, MacMillan F, McDevitt CA, O'Mara ML. Characterizing the conformational dynamics of metal-free PsaA using molecular dynamics simulations and electron paramagnetic resonance spectroscopy. Biophysical Chemistry. 207: 51-60. PMID 26379256 DOI: 10.1016/J.Bpc.2015.08.004  0.328
2015 Subramanian N, Condic-Jurkic K, Mark AE, O'Mara ML. Identification of Possible Binding Sites for Morphine and Nicardipine on the Multidrug Transporter P-Glycoprotein Using Umbrella Sampling Techniques. Journal of Chemical Information and Modeling. 55: 1202-17. PMID 25938863 DOI: 10.1021/ci5007382  0.337
2014 O'Mara ML, Mark AE. Structural characterization of two metastable ATP-bound states of P-glycoprotein Plos One. 9. PMID 24632881 DOI: 10.1371/journal.pone.0091916  0.339
2014 van Wonderen JH, McMahon RM, O'Mara ML, McDevitt CA, Thomson AJ, Kerr ID, MacMillan F, Callaghan R. The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis. The Febs Journal. 281: 2190-201. PMID 24597976 DOI: 10.1111/Febs.12773  0.378
2014 Plumptre CD, Eijkelkamp BA, Morey JR, Behr F, Couñago RM, Ogunniyi AD, Kobe B, O'Mara ML, Paton JC, McDevitt CA. AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae. Molecular Microbiology. 91: 834-51. PMID 24428621 DOI: 10.1111/Mmi.12504  0.363
2014 Couñago RM, Ween MP, Begg SL, Bajaj M, Zuegg J, O'Mara ML, Cooper MA, McEwan AG, Paton JC, Kobe B, McDevitt CA. Imperfect coordination chemistry facilitates metal ion release in the Psa permease. Nature Chemical Biology. 10: 35-41. PMID 24212134 DOI: 10.1038/Nchembio.1382  0.318
2013 Jia Z, O'Mara ML, Zuegg J, Cooper MA, Mark AE. Vancomycin: ligand recognition, dimerization and super-complex formation. The Febs Journal. 280: 1294-307. PMID 23298227 DOI: 10.1111/Febs.12121  0.337
2013 Jia ZG, O'Mara ML, Zuegg J, Cooper M, Mark A. Erratum: The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II (Biophysical Journal (2011) 101 (2684-2692)) Biophysical Journal. 104: 516-516. DOI: 10.1016/J.Bpj.2012.12.031  0.32
2012 Fairweather SJ, Bröer A, O'Mara ML, Bröer S. Intestinal peptidases form functional complexes with the neutral amino acid transporter B(0)AT1. The Biochemical Journal. 446: 135-48. PMID 22677001 DOI: 10.1042/Bj20120307  0.359
2011 Jia Z, O'Mara ML, Zuegg J, Cooper MA, Mark AE. The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II. Biophysical Journal. 101: 2684-92. PMID 22261057 DOI: 10.1016/J.Bpj.2011.10.047  0.325
2009 Oancea G, O'Mara ML, Bennett WF, Tieleman DP, Abele R, Tampé R. Structural arrangement of the transmission interface in the antigen ABC transport complex TAP. Proceedings of the National Academy of Sciences of the United States of America. 106: 5551-6. PMID 19297616 DOI: 10.1073/Pnas.0811260106  0.409
2009 Procko E, O'Mara ML, Bennett WF, Tieleman DP, Gaudet R. The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1287-302. PMID 19174475 DOI: 10.1096/Fj.08-121855  0.381
2008 Moussatova A, Kandt C, O'Mara ML, Tieleman DP. ATP-binding cassette transporters in Escherichia coli. Biochimica Et Biophysica Acta. 1778: 1757-71. PMID 18634750 DOI: 10.1016/J.Bbamem.2008.06.009  0.404
2007 Lawson J, O'Mara ML, Kerr ID. Structure-based interpretation of the mutagenesis database for the nucleotide binding domains of P-glycoprotein. Biochimica Et Biophysica Acta. 1778: 376-91. PMID 18035039 DOI: 10.1016/J.Bbamem.2007.10.021  0.383
2007 O'Mara ML, Tieleman DP. P-glycoprotein models of the apo and ATP-bound states based on homology with Sav1866 and MalK. Febs Letters. 581: 4217-22. PMID 17706648 DOI: 10.1016/J.Febslet.2007.07.069  0.357
2006 O'Mara M, Oakley A, Broer S. Mechanism and putative structure of B0-like neutral amino acid transporters The Journal of Membrane Biology. 213: 111-118. PMID 17417702 DOI: 10.1007/S00232-006-0879-3  0.363
2006 Oloo EO, Kandt C, O'Mara ML, Tieleman DP. Computer simulations of ABC transporter components. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 84: 900-11. PMID 17215877 DOI: 10.1139/o06-182  0.301
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