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Michael Knapp, Ph.D. - Publications

Affiliations: 
Chemistry University of Massachusetts, Amherst, Amherst, MA 
Area:
Enzymology and Bio-Inorganic Chemistry Enzymology and Electronic Structure of Non-heme Fe, Hydrogen Tunneling Effects in Biological C-H Activation, Biomimetic Nanocluster Self-Assembly
Website:
http://www.chem.umass.edu/faculty/knapp.html
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50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Martin CB, Taabazuing CY, Knapp MJ. Dynamic Domain Links Substrate Binding and Catalysis in the Factor-Inhibiting-HIF-1. Biochemistry. PMID 37526986 DOI: 10.1021/acs.biochem.3c00231  0.314
2021 Mingroni MA, Knapp MJ. Kinetic Studies of the Hydrogen Atom Transfer in a Hypoxia-Sensing Enzyme, FIH-1: KIE and O Reactivity. Biochemistry. 60: 3315-3322. PMID 34714626 DOI: 10.1021/acs.biochem.1c00476  0.382
2018 Chaplin VD, Hangasky JA, Huang HT, Duan R, Maroney MJ, Knapp MJ. Chloride Supports O Activation in the D201G Facial Triad Variant of Factor-Inhibiting Hypoxia Inducible Factor, an α-Ketoglutarate Dependent Oxygenase. Inorganic Chemistry. PMID 30252455 DOI: 10.1021/Acs.Inorgchem.8B01736  0.387
2018 Iyer SR, Chaplin VD, Knapp MJ, Solomon EI. O Activation by Nonheme Fe α-Ketoglutarate Dependent Enzyme Variants: Elucidating the Role of the Facial Triad Carboxylate in FIH. Journal of the American Chemical Society. PMID 30148961 DOI: 10.1021/Jacs.8B07277  0.397
2017 Chaplin VD, Valliere MA, Hangasky JA, Knapp MJ. Investigations on the role of a solvent tunnel in the α-ketoglutarate dependent oxygenase factor inhibiting HIF (FIH). Journal of Inorganic Biochemistry. 178: 63-69. PMID 29078149 DOI: 10.1016/j.jinorgbio.2017.10.001  0.393
2016 Hangasky JA, Taabazuing CY, Martin CB, Eron SJ, Knapp MJ. The facial triad in the α-ketoglutarate dependent oxygenase FIH: A role for sterics in linking substrate binding to O2 activation. Journal of Inorganic Biochemistry. 166: 26-33. PMID 27815979 DOI: 10.1016/j.jinorgbio.2016.10.007  0.378
2016 Taabazuing CY, Fermann J, Garman S, Knapp MJ. Substrate Promotes Productive Gas Binding in the α-Ketoglutarate-Dependent Oxygenase FIH. Biochemistry. PMID 26727884 DOI: 10.1021/Acs.Biochem.5B01003  0.36
2015 Pektas S, Taabazuing CY, Knapp MJ. Increased Turnover at Limiting O2 Concentrations by the Thr(387) → Ala Variant of HIF-Prolyl Hydroxylase PHD2. Biochemistry. 54: 2851-7. PMID 25857330 DOI: 10.1021/Bi501540C  0.793
2014 Hangasky JA, Gandhi H, Valliere MA, Ostrom NE, Knapp MJ. The rate-limiting step of O2 activation in the α-ketoglutarate oxygenase factor inhibiting hypoxia inducible factor. Biochemistry. 53: 8077-84. PMID 25423620 DOI: 10.1021/Bi501246V  0.323
2014 Hangasky JA, Ivison GT, Knapp MJ. Substrate positioning by Gln(239) stimulates turnover in factor inhibiting HIF, an αKG-dependent hydroxylase. Biochemistry. 53: 5750-8. PMID 25119663 DOI: 10.1021/bi500703s  0.386
2014 Taabazuing CY, Hangasky JA, Knapp MJ. Oxygen sensing strategies in mammals and bacteria. Journal of Inorganic Biochemistry. 133: 63-72. PMID 24468676 DOI: 10.1016/j.jinorgbio.2013.12.010  0.332
2014 Light KM, Hangasky JA, Knapp MJ, Solomon EI. First- and second-sphere contributions to Fe(II) site activation by cosubstrate binding in non-heme Fe enzymes. Dalton Transactions (Cambridge, England : 2003). 43: 1505-8. PMID 24292428 DOI: 10.1039/C3Dt53201A  0.342
2013 Pektas S, Knapp MJ. Substrate preference of the HIF-prolyl hydroxylase-2 (PHD2) and substrate-induced conformational change. Journal of Inorganic Biochemistry. 126: 55-60. PMID 23787140 DOI: 10.1016/J.Jinorgbio.2013.05.006  0.77
2013 Light KM, Hangasky JA, Knapp MJ, Solomon EI. Spectroscopic studies of the mononuclear non-heme Fe(II) enzyme FIH: second-sphere contributions to reactivity. Journal of the American Chemical Society. 135: 9665-74. PMID 23742069 DOI: 10.1021/Ja312571M  0.356
2013 Hangasky JA, Saban E, Knapp MJ. Inverse solvent isotope effects arising from substrate triggering in the factor inhibiting hypoxia inducible factor. Biochemistry. 52: 1594-602. PMID 23351038 DOI: 10.1021/Bi3015482  0.789
2012 Flagg SC, Giri N, Pektas S, Maroney MJ, Knapp MJ. Inverse solvent isotope effects demonstrate slow aquo release from hypoxia inducible factor-prolyl hydroxylase (PHD2). Biochemistry. 51: 6654-66. PMID 22747465 DOI: 10.1021/Bi300229Y  0.734
2012 Flagg SC, Martin CB, Taabazuing CY, Holmes BE, Knapp MJ. Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH). Journal of Inorganic Biochemistry. 113: 25-30. PMID 22687491 DOI: 10.1016/J.Jinorgbio.2012.03.002  0.76
2011 Saban E, Chen YH, Hangasky JA, Taabazuing CY, Holmes BE, Knapp MJ. The second coordination sphere of FIH controls hydroxylation. Biochemistry. 50: 4733-40. PMID 21456582 DOI: 10.1021/Bi102042T  0.797
2011 Saban E, Flagg SC, Knapp MJ. Uncoupled O2-activation in the human HIF-asparaginyl hydroxylase, FIH, does not produce reactive oxygen species. Journal of Inorganic Biochemistry. 105: 630-6. PMID 21443853 DOI: 10.1016/J.Jinorgbio.2011.01.007  0.734
2009 Germain ME, Knapp MJ. Optical explosives detection: from color changes to fluorescence turn-on. Chemical Society Reviews. 38: 2543-55. PMID 19690735 DOI: 10.1039/b809631g  0.519
2009 Carver AM, De M, Bayraktar H, Rana S, Rotello VM, Knapp MJ. Intermolecular electron-transfer catalyzed on nanoparticle surfaces. Journal of the American Chemical Society. 131: 3798-9. PMID 19243185 DOI: 10.1021/Ja806064T  0.746
2008 Bayraktar H, Srivastava S, You CC, Rotello VM, Knapp MJ. Controlled nanoparticleassembly through protein conformational changes. Soft Matter. 4: 751-756. PMID 32907180 DOI: 10.1039/B716386J  0.504
2008 Chen YH, Comeaux LM, Eyles SJ, Knapp MJ. Auto-hydroxylation of FIH-1: an Fe(ii), alpha-ketoglutarate-dependent human hypoxia sensor. Chemical Communications (Cambridge, England). 4768-70. PMID 18830487 DOI: 10.1039/B809099H  0.568
2008 Germain ME, Knapp MJ. Turn-on fluorescence detection of H2O2 and TATP. Inorganic Chemistry. 47: 9748-50. PMID 18828585 DOI: 10.1021/ic801317x  0.554
2008 Chen YH, Comeaux LM, Herbst RW, Saban E, Kennedy DC, Maroney MJ, Knapp MJ. Coordination changes and auto-hydroxylation of FIH-1: uncoupled O2-activation in a human hypoxia sensor. Journal of Inorganic Biochemistry. 102: 2120-9. PMID 18805587 DOI: 10.1016/J.Jinorgbio.2008.07.018  0.801
2008 Germain ME, Vargo TR, McClure BA, Rack JJ, Van Patten PG, Odoi M, Knapp MJ. Quenching mechanism of Zn(salicylaldimine) by nitroaromatics. Inorganic Chemistry. 47: 6203-11. PMID 18576611 DOI: 10.1021/Ic702469Q  0.554
2008 Germain ME, Knapp MJ. Discrimination of nitroaromatics and explosives mimics by a fluorescent Zn(salicylaldimine) sensor array. Journal of the American Chemical Society. 130: 5422-3. PMID 18376839 DOI: 10.1021/ja800403k  0.541
2008 Bayraktar H, Srivastava S, You CC, Rotello VM, Knapp MJ. Controlled nanoparticle assembly through protein conformational changes Soft Matter. 4: 751-756. DOI: 10.1039/b716386j  0.484
2008 Carver AM, Knapp MJ. Electron and energy-transfer reactions of Ru (bpy)3 2 + * / 3 + with copper-phenolates Polyhedron. 27: 3313-3317. DOI: 10.1016/J.Poly.2008.07.016  0.717
2007 Germain ME, Vargo TR, Khalifah PG, Knapp MJ. Fluorescent detection of nitroaromatics and 2,3-dimethyl 2,3-dinitrobutane (DMNB) by a zinc complex: (salophen)Zn. Inorganic Chemistry. 46: 4422-9. PMID 17472370 DOI: 10.1021/Ic062012C  0.55
2007 Sandanaraj BS, Bayraktar H, Krishnamoorthy K, Knapp MJ, Thayumanavan S. Recognition and modulation of cytochrome c's redox properties using an amphiphilic homopolymer. Langmuir : the Acs Journal of Surfaces and Colloids. 23: 3891-7. PMID 17315896 DOI: 10.1021/La063063P  0.516
2007 Bayraktar H, You CC, Rotello VM, Knapp MJ. Facial control of nanoparticle binding to cytochrome C. Journal of the American Chemical Society. 129: 2732-3. PMID 17309259 DOI: 10.1021/Ja067497I  0.517
2007 Knapp MJ, Meyer M, Klinman JP. Nuclear Tunneling in the Condensed Phase: Hydrogen Transfer in Enzyme Reactions Hydrogen-Transfer Reactions. 4: 1241-1284. DOI: 10.1002/9783527611546.ch39  0.442
2006 Bayraktar H, Ghosh PS, Rotello VM, Knapp MJ. Disruption of protein-protein interactions using nanoparticles: inhibition of cytochrome c peroxidase. Chemical Communications (Cambridge, England). 1390-2. PMID 16550276 DOI: 10.1039/B516096K  0.524
2003 Knapp MJ, Klinman JP. Kinetic studies of oxygen reactivity in soybean lipoxygenase-1. Biochemistry. 42: 11466-75. PMID 14516198 DOI: 10.1021/Bi0300884  0.561
2002 Francisco WA, Knapp MJ, Blackburn NJ, Klinman JP. Hydrogen tunneling in peptidylglycine alpha-hydroxylating monooxygenase. Journal of the American Chemical Society. 124: 8194-5. PMID 12105892 DOI: 10.1021/Ja025758S  0.473
2002 Knapp MJ, Klinman JP. Environmentally coupled hydrogen tunneling. Linking catalysis to dynamics. European Journal of Biochemistry / Febs. 269: 3113-21. PMID 12084051 DOI: 10.1046/J.1432-1033.2002.03022.X  0.457
2002 Sañudo EC, Grillo VA, Knapp MJ, Bollinger JC, Huffman JC, Hendrickson DN, Christou G. Tetranuclear manganese complexes with dimer-of-dimer and ladder structures from the use of a bis-bipyridyl ligand. Inorganic Chemistry. 41: 2441-50. PMID 11978111 DOI: 10.1021/Ic011262K  0.458
2002 Knapp MJ, Rickert K, Klinman JP. Temperature-dependent isotope effects in soybean lipoxygenase-1: correlating hydrogen tunneling with protein dynamics. Journal of the American Chemical Society. 124: 3865-74. PMID 11942823 DOI: 10.1021/Ja012205T  0.463
2001 Knapp MJ, Seebeck FP, Klinman JP. Steric control of oxygenation regiochemistry in soybean lipoxygenase-1. Journal of the American Chemical Society. 123: 2931-2. PMID 11457000 DOI: 10.1021/Ja003855K  0.447
2000 Knapp MJ, Krzystek J, Brunel LC, Hendrickson DN. High-frequency EPR study of the ferrous ion in the reduced rubredoxin model. Inorganic Chemistry. 39: 281-8. PMID 11272536 DOI: 10.1021/Ic9910054  0.405
2000 Maes EM, Knapp MJ, Czernuszewicz RS, Hendrickson DN. Ligand Conformational Effects on the Resonance Raman Signature of [Fe4S4(SAryl)4]2-Clusters† The Journal of Physical Chemistry B. 104: 10878-10884. DOI: 10.1021/jp0003104  0.349
2000 Brechin EK, Knapp MJ, Huffman JC, Hendrickson DN, Christou G. New hexanuclear and octanuclear iron(III) oxide clusters: Octahedral [Fe6O2]14+ species and core isomerism in [Fe8O4]16+ complexes Inorganica Chimica Acta. 297: 389-399. DOI: 10.1016/S0020-1693(99)00377-1  0.512
1999 Knapp MJ, Krzystek J, Brunel LC, Hendrickson DN. High-Field EPR Study of Resonance-Delocalized [Fe(2)(OH)(3)(tmtacn)(2)](2+). Inorganic Chemistry. 38: 3321-3328. PMID 11671067 DOI: 10.1021/Ic9901012  0.419
1999 Aromí G, Knapp MJ, Claude JP, Huffman JC, Hendrickson DN, Christou G. High-spin molecules: Hexanuclear Mn(III) clusters with [Mn6O4X4]6+ (X = Cl-, Br-) face-capped octahedral cores and S = 12 ground states Journal of the American Chemical Society. 121: 5489-5499. DOI: 10.1021/Ja983446C  0.411
1998 Grant CM, Knapp MJ, Streib WE, Huffman JC, Hendrickson DN, Christou G. Dinuclear and Hexanuclear Iron(III) Oxide Complexes with a Bis(bipyridine) Ligand: A New [Fe(6)(&mgr;(3)-O)(4)](10+) Core. Inorganic Chemistry. 37: 6065-6070. PMID 11670744 DOI: 10.1021/Ic980686K  0.501
1998 Seela JL, Knapp MJ, Kolack KS, Chang HR, Huffman JC, Hendrickson DN, Christou G. Structural and Magnetochemical Properties of Mono-, Di-, and Trinuclear Manganese(III) Dithiolate Complexes. Inorganic Chemistry. 37: 516-525. PMID 11670303 DOI: 10.1021/Ic970587R  0.395
1998 Aromí G, Claude J, Knapp MJ, Huffman JC, Hendrickson DN, Christou G. High-Spin Molecules:  Hexanuclear [Mn6O4Cl4(Me2dbm)6] (Me2dbmH = 4,4‘-Dimethyldibenzoylmethane) with a Near Tetrahedral [Mn6O4Cl4]6+Core and aS= 12 Ground State Journal of the American Chemical Society. 120: 2977-2978. DOI: 10.1021/Ja973996V  0.421
1996 Knapp MJ, Hendrickson DN, Grillo VA, Bollinger JC, Christou G. Bis(bipyridine) Ligands in Manganese Carboxylate Cluster Chemistry: Self-Assembly of a Cluster Complex with Two Butterfly-Like[Mn4(μ3-O)2]8+ Cores Angewandte Chemie International Edition in English. 35: 1818-1820. DOI: 10.1002/Anie.199618181  0.392
1996 Grillo VA, Knapp MJ, Bollinger JC, Hendrickson DN, Christou G. Bis(bipyridin)-Liganden bei Carboxylatomangan-Clustern: Selbstorganisation eines Clusterkomplexes mit zwei schmetterlingsförmigen [Mn4(μ3-O)2]8+-Einheiten Angewandte Chemie. 108: 1962-1964. DOI: 10.1002/Ange.19961081622  0.461
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