| Year |
Citation |
Score |
| 2023 |
Liang TJ, Law JLM, Pietschmann T, Ray SC, Bukh J, Bull R, Chung RT, Tyrrell DL, Houghton M, Rice CM. Challenge Inoculum for Hepatitis C Virus Controlled Human Infection Model. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 77: S257-S261. PMID 37579208 DOI: 10.1093/cid/ciad336 |
0.457 |
|
| 2022 |
Kanai T, Hu Z, Yang R, Wu W, Wang Z, Ma CD, Sanchez-Meza J, Law M, Houghton M, Law JL, Logan M, de Val N, Liang TJ. Three-Dimensional Reconstruction of the Hepatitis C Virus Envelope Glycoprotein E1E2 Heterodimer by Electron Microscopic Analysis. Journal of Virology. e0178822. PMID 36519897 DOI: 10.1128/jvi.01788-22 |
0.412 |
|
| 2020 |
Zietara F, Crotty P, Houghton M, Tyrrell L, Coffin CS, Macphail G. Sociodemographic risk factors for hepatitis C virus infection in a prospective cohort study of 257 persons in Canada who inject drugs. Canadian Liver Journal. 3: 276-285. PMID 35992530 DOI: 10.3138/canlivj.2019-0023 |
0.49 |
|
| 2020 |
Gindin Y, Chung C, Jiang Z, Zhou JZ, Xu J, Billin A, Myers RP, Goodman Z, Landi A, Houghton M, Green RM, Levy C, Kowdley KV, Bowlus CL, Muir AJ, et al. A Fibrosis-Independent Hepatic Transcriptomic Signature Identifies Novel Drivers of Disease Progression in Primary Sclerosing Cholangitis. Hepatology (Baltimore, Md.). PMID 32745270 DOI: 10.1002/Hep.31488 |
0.317 |
|
| 2020 |
Hu Z, Rolt A, Hu X, Ma CD, Le DJ, Park SB, Houghton M, Southall N, Anderson DE, Talley DC, Lloyd JR, Marugan JC, Liang TJ. Chlorcyclizine Inhibits Viral Fusion of Hepatitis C Virus Entry by Directly Targeting HCV Envelope Glycoprotein 1. Cell Chemical Biology. PMID 32386595 DOI: 10.1016/J.Chembiol.2020.04.006 |
0.592 |
|
| 2020 |
Santer DM, Minty GES, Golec DP, Lu J, May J, Namdar A, Shah J, Elahi S, Proud D, Joyce M, Tyrrell DL, Houghton M. Differential expression of interferon-lambda receptor 1 splice variants determines the magnitude of the antiviral response induced by interferon-lambda 3 in human immune cells. Plos Pathogens. 16: e1008515. PMID 32353085 DOI: 10.1371/Journal.Ppat.1008515 |
0.376 |
|
| 2020 |
Zhang D, Zhang X, Xu L, Tyrrell DL, Houghton M, Ba-Thein W. Seroepidemiology of Hepatitis C Among Drug Users at a Detoxification Center in Southeast China Hepatitis Monthly. 20. DOI: 10.5812/Hepatmon.99249 |
0.38 |
|
| 2020 |
Zietara F, Crotty P, Houghton M, Tyrrell L, Coffin C, Macphail G. Sociodemographic risk factors for hepatitis C virus infection in a prospective cohort study of 257 persons in Canada who inject drugs Canadian Liver Journal. 3: 276-285. DOI: 10.3138/canlivj.2019-0023 |
0.329 |
|
| 2019 |
Akache B, Deschatelets L, Harrison BA, Dudani R, Stark FC, Jia Y, Landi A, Law JLM, Logan M, Hockman D, Kundu J, Tyrrell DL, Krishnan L, Houghton M, McCluskie MJ. Effect of Different Adjuvants on the Longevity and Strength of Humoral and Cellular Immune Responses to the HCV Envelope Glycoproteins. Vaccines. 7. PMID 31816920 DOI: 10.3390/Vaccines7040204 |
0.613 |
|
| 2019 |
Houghton M. Hepatitis C Virus: 30 Years after Its Discovery. Cold Spring Harbor Perspectives in Medicine. PMID 31501269 DOI: 10.1101/Cshperspect.A037069 |
0.539 |
|
| 2019 |
Johnson J, Freedman H, Logan M, Wong JAJ, Hockman D, Chen C, He J, Beard MR, Eyre NS, Baumert TF, Tyrrell DL, Law JLM, Houghton M. A recombinant HCV genotype 1a E1/E2 envelope glycoprotein vaccine elicits antibodies that differentially neutralize closely related 2a strains through interactions of the N-terminal hypervariable region 1 of E2 with scavenger receptor B1. Journal of Virology. PMID 31462563 DOI: 10.1128/Jvi.00810-19 |
0.574 |
|
| 2019 |
Banda DH, Perin PM, Brown RJP, Todt D, Solodenko W, Hoffmeyer P, Sahu KK, Houghton M, Meuleman P, Müller R, Kirschning A, Pietschmann T. A central hydrophobic E1 region controls the pH range of hepatitis C virus membrane fusion and susceptibility to fusion inhibitors. Journal of Hepatology. PMID 30769006 DOI: 10.1016/J.Jhep.2019.01.033 |
0.529 |
|
| 2018 |
Law JL, Logan M, Landi A, Tyrrell DL, Houghton M. Progress toward approval of an HCV vaccine. Canadian Liver Journal. 1: 130-138. PMID 35991323 DOI: 10.3138/canlivj.2018.0010 |
0.458 |
|
| 2018 |
Khera T, Behrendt P, Bankwitz D, Brown RJP, Todt D, Doepke M, Ghafoor Khan A, Schulze K, Law J, Logan M, Hockman D, Wong JAJ, Dold L, Gonzalez-Motos V, Spengler U, ... ... Houghton M, et al. Functional and immunogenic characterization of diverse HCV glycoprotein E2 variants. Journal of Hepatology. PMID 30439392 DOI: 10.1016/J.Jhep.2018.11.003 |
0.529 |
|
| 2018 |
Law JLM, Logan M, Wong J, Kundu J, Hockman D, Landi A, Chen C, Crawford K, Wininger M, Johnson J, Mesa Prince C, Dudek E, Mehta N, Tyrrell DL, Houghton M. Role of the E2 hypervariable region (HVR1) in the immunogenicity of a recombinant HCV vaccine. Journal of Virology. PMID 29540595 DOI: 10.1128/Jvi.02141-17 |
0.475 |
|
| 2018 |
Bartenschlager R, Baumert TF, Bukh J, Houghton M, Lemon SM, Lindenbach BD, Lohmann V, Moradpour D, Pietschmann T, Rice CM, Thimme R, Wakita T. Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: considerations for scientists and funding agencies. Virus Research. PMID 29477639 DOI: 10.1016/J.Virusres.2018.02.016 |
0.617 |
|
| 2017 |
Landi A, Law J, Hockman D, Logan M, Crawford K, Chen C, Kundu J, Ebensen T, Guzman CA, Deschatelets L, Krishnan L, Tyrrell DLJ, Houghton M. Superior immunogenicity of HCV envelope glycoproteins when adjuvanted with cyclic-di-AMP, a STING activator or archaeosomes. Vaccine. PMID 29089195 DOI: 10.1016/J.Vaccine.2017.10.072 |
0.56 |
|
| 2017 |
Okoye IS, Houghton M, Tyrrell L, Barakat K, Elahi S. Coinhibitory Receptor Expression and Immune Checkpoint Blockade: Maintaining a Balance in CD8(+) T Cell Responses to Chronic Viral Infections and Cancer. Frontiers in Immunology. 8: 1215. PMID 29033936 DOI: 10.3389/Fimmu.2017.01215 |
0.375 |
|
| 2017 |
Sarhan MA, Abdel-Hakeem MS, Mason AL, Tyrrell DL, Houghton M. Glycogen synthase kinase 3β inhibitors prevent hepatitis C virus release/assembly through perturbation of lipid metabolism. Scientific Reports. 7: 2495. PMID 28566716 DOI: 10.1038/S41598-017-02648-6 |
0.813 |
|
| 2017 |
Santer DM, Minty GE, Mohamed A, Baldwin L, Bhat R, Joyce M, Egli A, Tyrrell DL, Houghton M. A novel method for detection of IFN-lambda 3 binding to cells for quantifying IFN-lambda receptor expression. Journal of Immunological Methods. PMID 28274837 DOI: 10.1016/J.Jim.2017.03.001 |
0.322 |
|
| 2017 |
Freedman H, Logan MR, Hockman D, Leman JK, Law JL, Houghton M. Computational prediction of the heterodimeric and higher order structure of gpE1/gpE2 envelope glycoproteins encoded by the hepatitis C virus (HCV). Journal of Virology. PMID 28148799 DOI: 10.1128/Jvi.02309-16 |
0.492 |
|
| 2016 |
Ahmed M, Pal A, Houghton M, Barakat K. A Comprehensive Computational Analysis for the Binding Modes of Hepatitis C Virus NS5A Inhibitors: The Question of Symmetry. Acs Infectious Diseases. 2: 872-881. PMID 27933783 DOI: 10.1021/Acsinfecdis.6B00113 |
0.505 |
|
| 2016 |
Freedman H, Logan MR, Law JL, Houghton M. Structure and Function of the Hepatitis C Virus Envelope Glycoproteins E1 and E2: Antiviral and Vaccine Targets. Acs Infectious Diseases. 2: 749-762. PMID 27933781 DOI: 10.1021/Acsinfecdis.6B00110 |
0.509 |
|
| 2016 |
Logan M, Law J, Wong JA, Hockman D, Landi A, Chen C, Crawford K, Kundu J, Baldwin L, Johnson J, Dahiya A, LaChance G, Marcotrigiano J, Law M, Foung S, ... ... Houghton M, et al. Native folding of a recombinant gpE1/gpE2 heterodimer vaccine antigen from a precursor protein fused with Fc IgG. Journal of Virology. PMID 27795422 DOI: 10.1128/Jvi.01552-16 |
0.47 |
|
| 2015 |
O'Shea D, Law J, Egli A, Douglas D, Lund G, Forester S, Lambert J, Law M, Burton DR, Tyrrell DL, Houghton M, Humar A, Kneteman N. Prevention of HCV infection using a broad cross-neutralizing monoclonal antibody (AR4A) and Epigallocatechin-Gallate. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. PMID 26389583 DOI: 10.1002/Lt.24344 |
0.615 |
|
| 2015 |
Ahmed M, Wang F, Levin A, Le C, Eltayebi Y, Houghton M, Tyrrell L, Barakat K. Targeting the Achilles heel of the hepatitis B virus: a review of current treatments against covalently closed circular DNA. Drug Discovery Today. 20: 548-61. PMID 25622780 DOI: 10.1016/J.Drudis.2015.01.008 |
0.446 |
|
| 2015 |
Barakat KH, Anwar-Mohamed A, Tuszynski JA, Robins MJ, Tyrrell DL, Houghton M. A Refined Model of the HCV NS5A protein bound to daclatasvir explains drug-resistant mutations and activity against divergent genotypes. Journal of Chemical Information and Modeling. 55: 362-73. PMID 24730573 DOI: 10.1021/Ci400631N |
0.541 |
|
| 2014 |
Egli A, Santer DM, O'Shea D, Tyrrell DL, Houghton M. The impact of the interferon-lambda family on the innate and adaptive immune response to viral infections. Emerging Microbes & Infections. 3: e51. PMID 26038748 DOI: 10.1038/Emi.2014.51 |
0.404 |
|
| 2014 |
MacParland SA, Bilodeau M, Grebely J, Bruneau J, Cooper C, Klein M, Sagan S, Choucha N, Balfour L, Bialystok F, Krajden M, Raven J, Roberts E, Russell R, Houghton M, et al. The 3rd Canadian Symposium on Hepatitis C Virus: expanding care in the interferon-free era. Canadian Journal of Gastroenterology & Hepatology. 28: 481-7. PMID 25314353 DOI: 10.1155/2014/704919 |
0.599 |
|
| 2014 |
Wong JA, Bhat R, Hockman D, Logan M, Chen C, Levin A, Frey SE, Belshe RB, Tyrrell DL, Law JL, Houghton M. Recombinant hepatitis C virus envelope glycoprotein vaccine elicits antibodies targeting multiple epitopes on the envelope glycoproteins associated with broad cross-neutralization. Journal of Virology. 88: 14278-88. PMID 25275133 DOI: 10.1128/JVI.01911-14 |
0.488 |
|
| 2014 |
Houghton M. Hepatitis C: the next 25years. Antiviral Research. 110: 77-8. PMID 25043637 DOI: 10.1016/J.Antiviral.2014.06.018 |
0.466 |
|
| 2014 |
Colombatto P, Brunetto MR, Maina AM, Romagnoli V, Almasio P, Rumi MG, Ascione A, Pinzello G, Mondelli M, Muratori L, Rappuoli R, Rosa D, Houghton M, Abrignani S, Bonino F. HCV E1E2-MF59 vaccine in chronic hepatitis C patients treated with PEG-IFNα2a and Ribavirin: a randomized controlled trial. Journal of Viral Hepatitis. 21: 458-65. PMID 24750327 DOI: 10.1111/Jvh.12163 |
0.489 |
|
| 2014 |
Landi A, Weismuller TJ, Lankisch TO, Santer DM, Tyrrell DL, Manns MP, Houghton M. Differential serum levels of eosinophilic eotaxins in primary sclerosing cholangitis, primary biliary cirrhosis, and autoimmune hepatitis. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 34: 204-14. PMID 24168449 DOI: 10.1089/Jir.2013.0075 |
0.432 |
|
| 2013 |
Man John Law L, Landi A, Magee WC, Lorne Tyrrell D, Houghton M. Progress towards a hepatitis C virus vaccine. Emerging Microbes & Infections. 2: e79. PMID 26038445 DOI: 10.1038/Emi.2013.79 |
0.602 |
|
| 2013 |
Grebely J, Bilodeau M, Feld JJ, Bruneau J, Fischer B, Raven JF, Roberts E, Choucha N, Myers RP, Sagan SM, Wilson JA, Bialystok F, Tyrrell DL, Houghton M, Krajden M, et al. The Second Canadian Symposium on hepatitis C virus: a call to action. Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 27: 627-32. PMID 24199209 DOI: 10.1155/2013/242405 |
0.589 |
|
| 2013 |
Barakat KH, Law J, Prunotto A, Magee WC, Evans DH, Tyrrell DL, Tuszynski J, Houghton M. Detailed computational study of the active site of the hepatitis C viral RNA polymerase to aid novel drug design. Journal of Chemical Information and Modeling. 53: 3031-43. PMID 24116674 DOI: 10.1021/Ci4003969 |
0.539 |
|
| 2013 |
Santer DM, Ma MM, Hockman D, Landi A, Tyrrell DL, Houghton M. Enhanced activation of memory, but not naïve, B cells in chronic hepatitis C virus-infected patients with cryoglobulinemia and advanced liver fibrosis. Plos One. 8: e68308. PMID 23840845 DOI: 10.1371/Journal.Pone.0068308 |
0.608 |
|
| 2013 |
Houghton M, Law JL, Tyrrell DL. An inactivated hepatitis C virus vaccine on the horizon? Gastroenterology. 145: 285-8. PMID 23806539 DOI: 10.1053/J.Gastro.2013.06.029 |
0.469 |
|
| 2013 |
Steenbergen RH, Joyce MA, Thomas BS, Jones D, Law J, Russell R, Houghton M, Tyrrell DL. Human serum leads to differentiation of human hepatoma cells, restoration of very-low-density lipoprotein secretion, and a 1000-fold increase in HCV Japanese fulminant hepatitis type 1 titers. Hepatology (Baltimore, Md.). 58: 1907-17. PMID 23775894 DOI: 10.1002/Hep.26566 |
0.502 |
|
| 2013 |
Nourbakhsh M, Douglas DN, Pu CH, Lewis JT, Kawahara T, Lisboa LF, Wei E, Asthana S, Quiroga AD, Law LM, Chen C, Addison WR, Nelson R, Houghton M, Lehner R, et al. Arylacetamide deacetylase: a novel host factor with important roles in the lipolysis of cellular triacylglycerol stores, VLDL assembly and HCV production. Journal of Hepatology. 59: 336-43. PMID 23542347 DOI: 10.1016/J.Jhep.2013.03.022 |
0.58 |
|
| 2013 |
Law JL, Chen C, Wong J, Hockman D, Santer DM, Frey SE, Belshe RB, Wakita T, Bukh J, Jones CT, Rice CM, Abrignani S, Tyrrell DL, Houghton M. A hepatitis C virus (HCV) vaccine comprising envelope glycoproteins gpE1/gpE2 derived from a single isolate elicits broad cross-genotype neutralizing antibodies in humans. Plos One. 8: e59776. PMID 23527266 DOI: 10.1371/Journal.Pone.0059776 |
0.59 |
|
| 2012 |
Houghton M. Chimp virus makes a savvy vaccine vector. Science Translational Medicine. 4: 115fs1. PMID 22218689 DOI: 10.1126/Scitranslmed.3003526 |
0.428 |
|
| 2011 |
Steffen I, Tyrrell DL, Stein E, Montalvo L, Lee TH, Zhou Y, Lu K, Switzer WM, Tang S, Jia H, Hockman D, Santer DM, Logan M, Landi A, Law J, ... Houghton M, et al. No evidence for XMRV nucleic acids, infectious virus or anti-XMRV antibodies in Canadian patients with chronic fatigue syndrome. Plos One. 6: e27870. PMID 22114717 DOI: 10.1371/Journal.Pone.0027870 |
0.375 |
|
| 2011 |
Meunier JC, Gottwein JM, Houghton M, Russell RS, Emerson SU, Bukh J, Purcell RH. Vaccine-induced cross-genotype reactive neutralizing antibodies against hepatitis C virus. The Journal of Infectious Diseases. 204: 1186-90. PMID 21917891 DOI: 10.1093/Infdis/Jir511 |
0.512 |
|
| 2011 |
Stamataki Z, Coates S, Abrignani S, Houghton M, McKeating JA. Immunization of human volunteers with hepatitis C virus envelope glycoproteins elicits antibodies that cross-neutralize heterologous virus strains. The Journal of Infectious Diseases. 204: 811-3. PMID 21788452 DOI: 10.1093/Infdis/Jir399 |
0.555 |
|
| 2011 |
Houghton M. Prospects for prophylactic and therapeutic vaccines against the hepatitis C viruses. Immunological Reviews. 239: 99-108. PMID 21198667 DOI: 10.1111/J.1600-065X.2010.00977.X |
0.52 |
|
| 2010 |
Ray R, Meyer K, Banerjee A, Basu A, Coates S, Abrignani S, Houghton M, Frey SE, Belshe RB. Characterization of antibodies induced by vaccination with hepatitis C virus envelope glycoproteins. The Journal of Infectious Diseases. 202: 862-6. PMID 20677942 DOI: 10.1086/655902 |
0.594 |
|
| 2010 |
Frey SE, Houghton M, Coates S, Abrignani S, Chien D, Rosa D, Pileri P, Ray R, Di Bisceglie AM, Rinella P, Hill H, Wolff MC, Schultze V, Han JH, Scharschmidt B, et al. Safety and immunogenicity of HCV E1E2 vaccine adjuvanted with MF59 administered to healthy adults. Vaccine. 28: 6367-73. PMID 20619382 DOI: 10.1016/J.Vaccine.2010.06.084 |
0.602 |
|
| 2009 |
Houghton M. The long and winding road leading to the identification of the hepatitis C virus. Journal of Hepatology. 51: 939-48. PMID 19781804 DOI: 10.1016/J.Jhep.2009.08.004 |
0.55 |
|
| 2009 |
Drane D, Maraskovsky E, Gibson R, Mitchell S, Barnden M, Moskwa A, Shaw D, Gervase B, Coates S, Houghton M, Basser R. Priming of CD4+ and CD8+ T cell responses using a HCV core ISCOMATRIX vaccine: a phase I study in healthy volunteers. Human Vaccines. 5: 151-7. PMID 19246990 DOI: 10.4161/Hv.5.3.6614 |
0.533 |
|
| 2009 |
Houghton M. Discovery of the hepatitis C virus. Liver International : Official Journal of the International Association For the Study of the Liver. 29: 82-8. PMID 19207970 DOI: 10.1111/J.1478-3231.2008.01925.X |
0.643 |
|
| 2009 |
Houghton M. 147 Hepatitis C and cancer Jaids Journal of Acquired Immune Deficiency Syndromes. 51: 1. DOI: 10.1097/01.qai.0000351103.63266.73 |
0.301 |
|
| 2009 |
Colombatto P, Brunetto M, Maina A, Romagnoli V, Craxì A, Almasio P, Madonia S, Rumi M, Colombo M, Fargion S, Ascione A, Pinzello G, Mondelli M, Muzzi A, Bianchi F, ... ... Houghton M, et al. 602 THE CANDIDATE HCV E1E2MF59 VACCINE IS SAFE IN CHRONIC HEPATITIS C PATIENTS AND ACCELLERATES THE SECOND PHASE VIRAL DECLINE UPON PRIMARY RESPONSE TO PEG-INTERFERON-2A/RIBAVIRIN THERAPY Journal of Hepatology. 50: S221. DOI: 10.1016/S0168-8278(09)60604-8 |
0.558 |
|
| 2009 |
Colombatto P, Brunetto M, Maina A, Romagnoli V, Craxì A, Almasio P, Madonia S, Rumi M, Colombo M, Fargion S, Ascione A, Pinzello G, Mondelli M, Muzzi A, Bianchi F, ... ... Houghton M, et al. The candidate HCV E1E2MF59 vaccine enhances 2nd phase viral decline in responders to PEG-IFN/ribavirin Digestive and Liver Disease. 41: A19. DOI: 10.1016/J.Dld.2008.12.041 |
0.529 |
|
| 2008 |
Lin Y, Kwon T, Polo J, Zhu YF, Coates S, Crawford K, Dong C, Wininger M, Hall J, Selby M, Coit D, Medina-Selby A, McCoin C, Ng P, Drane D, ... ... Houghton M, et al. Induction of broad CD4+ and CD8+ T-cell responses and cross-neutralizing antibodies against hepatitis C virus by vaccination with Th1-adjuvanted polypeptides followed by defective alphaviral particles expressing envelope glycoproteins gpE1 and gpE2 and nonstructural proteins 3, 4, and 5. Journal of Virology. 82: 7492-503. PMID 18508900 DOI: 10.1128/Jvi.02743-07 |
0.531 |
|
| 2008 |
Bowen DG, Shoukry NH, Grakoui A, Fuller MJ, Cawthon AG, Dong C, Hasselschwert DL, Brasky KM, Freeman GJ, Seth NP, Wucherpfennig KW, Houghton M, Walker CM. Variable patterns of programmed death-1 expression on fully functional memory T cells after spontaneous resolution of hepatitis C virus infection. Journal of Virology. 82: 5109-14. PMID 18337576 DOI: 10.1128/Jvi.00060-08 |
0.46 |
|
| 2008 |
Nishioka K, Watanabe J, Furuta S, Tanaka E, Suzuki H, Iino S, Tsuji T, Yano M, Kuo G, Choo Q, Houghton M, Oda T. Antibody to the hepatitis C virus in acute hepatitis and chronic liver diseases in Japan. Liver. 11: 65-70. PMID 1646928 DOI: 10.1111/J.1600-0676.1991.Tb00494.X |
0.461 |
|
| 2008 |
Manns MP, Foster GR, Rockstroh JK, Zeuzem S, Zoulim F, Houghton M. Erratum: The way forward in HCV treatment — finding the right path Nature Reviews Drug Discovery. 7: 458-458. DOI: 10.1038/Nrd2570 |
0.441 |
|
| 2007 |
Manns MP, Foster GR, Rockstroh JK, Zeuzem S, Zoulim F, Houghton M. The way forward in HCV treatment--finding the right path. Nature Reviews. Drug Discovery. 6: 991-1000. PMID 18049473 DOI: 10.1038/Nrd2411 |
0.602 |
|
| 2007 |
Stamataki Z, Coates S, Evans MJ, Wininger M, Crawford K, Dong C, Fong YL, Chien D, Abrignani S, Balfe P, Rice CM, McKeating JA, Houghton M. Hepatitis C virus envelope glycoprotein immunization of rodents elicits cross-reactive neutralizing antibodies. Vaccine. 25: 7773-84. PMID 17919789 DOI: 10.1016/J.Vaccine.2007.08.053 |
0.518 |
|
| 2006 |
McLinden JH, Kaufman TM, Xiang J, Chang Q, Klinzman D, Engel AM, Hess G, Schmidt U, Houghton M, Stapleton JT. Characterization of an immunodominant antigenic site on GB virus C glycoprotein E2 that is involved in cell binding. Journal of Virology. 80: 12131-40. PMID 17035329 DOI: 10.1128/Jvi.01206-06 |
0.339 |
|
| 2006 |
Vajdy M, Selby M, Medina-Selby A, Coit D, Hall J, Tandeske L, Chien D, Hu C, Rosa D, Singh M, Kazzaz J, Nguyen S, Coates S, Ng P, Abrignani S, ... ... Houghton M, et al. Hepatitis C virus polyprotein vaccine formulations capable of inducing broad antibody and cellular immune responses. The Journal of General Virology. 87: 2253-62. PMID 16847121 DOI: 10.1099/Vir.0.81849-0 |
0.597 |
|
| 2006 |
Frey S, Gorse G, DiBisceglie A, Rosa D, Stamataki Z, McKeating J, Ray R, Coates S, Schultze V, Abrignan S, Houghton M, Hill H, Belshe R. O.015 A phase 1 trial of a novel E1E2/MF59C.1 hepatitis C vaccine candidate in healthy HCV-negative adults (DMID 01-002) Journal of Clinical Virology. 36: S5. DOI: 10.1016/S1386-6532(06)80024-7 |
0.412 |
|
| 2006 |
Lin Y, Polo J, Vajdy M, Houghton M. Su.64. Enhancement of Cd8+ T-Cell Responses to Hepatitis C Viral E1e2 Glycoprotein Using Defective Alphavirus Replicon Particle As a Delivery Vector Clinical Immunology. 119: S182. DOI: 10.1016/J.Clim.2006.04.491 |
0.405 |
|
| 2005 |
Rosa D, Saletti G, De Gregorio E, Zorat F, Comar C, D'Oro U, Nuti S, Houghton M, Barnaba V, Pozzato G, Abrignani S. Activation of naïve B lymphocytes via CD81, a pathogenetic mechanism for hepatitis C virus-associated B lymphocyte disorders. Proceedings of the National Academy of Sciences of the United States of America. 102: 18544-9. PMID 16339892 DOI: 10.1073/Pnas.0509402102 |
0.545 |
|
| 2005 |
Houghton M, Abrignani S. Prospects for a vaccine against the hepatitis C virus. Nature. 436: 961-6. PMID 16107836 DOI: 10.1038/Nature04081 |
0.431 |
|
| 2005 |
Nattermann J, Schneiders AM, Leifeld L, Langhans B, Schulz M, Inchauspé G, Matz B, Brackmann HH, Houghton M, Sauerbruch T, Spengler U. Serum antibodies against the hepatitis C virus E2 protein mediate antibody-dependent cellular cytotoxicity (ADCC). Journal of Hepatology. 42: 499-504. PMID 15763336 DOI: 10.1016/J.Jhep.2004.12.018 |
0.578 |
|
| 2005 |
Brazzoli M, Helenius A, Foung SK, Houghton M, Abrignani S, Merola M. Folding and dimerization of hepatitis C virus E1 and E2 glycoproteins in stably transfected CHO cells. Virology. 332: 438-53. PMID 15661174 DOI: 10.1016/J.Virol.2004.11.034 |
0.365 |
|
| 2004 |
O'Hagan DT, Singh M, Dong C, Ugozzoli M, Berger K, Glazer E, Selby M, Wininger M, Ng P, Crawford K, Paliard X, Coates S, Houghton M. Cationic microparticles are a potent delivery system for a HCV DNA vaccine. Vaccine. 23: 672-80. PMID 15542189 DOI: 10.1016/J.Vaccine.2004.06.037 |
0.341 |
|
| 2004 |
Masciopinto F, Giovani C, Campagnoli S, Galli-Stampino L, Colombatto P, Brunetto M, Yen TS, Houghton M, Pileri P, Abrignani S. Association of hepatitis C virus envelope proteins with exosomes. European Journal of Immunology. 34: 2834-42. PMID 15368299 DOI: 10.1002/Eji.200424887 |
0.608 |
|
| 2004 |
D'Ugo E, Paroli M, Palmieri G, Giuseppetti R, Argentini C, Tritarelli E, Bruni R, Barnaba V, Houghton M, Rapicetta M. Immunization of woodchucks with adjuvanted sHDAg (p24): immune response and outcome following challenge. Vaccine. 22: 457-66. PMID 14670328 DOI: 10.1016/J.Vaccine.2003.07.001 |
0.434 |
|
| 2003 |
Shoukry NH, Grakoui A, Houghton M, Chien DY, Ghrayeb J, Reimann KA, Walker CM. Memory CD8+ T cells are required for protection from persistent hepatitis C virus infection. The Journal of Experimental Medicine. 197: 1645-55. PMID 12810686 DOI: 10.1084/Jem.20030239 |
0.475 |
|
| 2003 |
Seo MY, Abrignani S, Houghton M, Han JH. Small interfering RNA-mediated inhibition of hepatitis C virus replication in the human hepatoma cell line Huh-7. Journal of Virology. 77: 810-2. PMID 12477890 DOI: 10.1128/Jvi.77.1.810-812.2003 |
0.594 |
|
| 2003 |
Nattermann J, Nischalke H-, Houghton M, Sauerbruch T, Spengler U. Down-regulation of CCR5 expression by hepatitis C virus Journal of Hepatology. 38: 116. DOI: 10.1016/S0168-8278(03)80663-3 |
0.489 |
|
| 2003 |
Nattermann J, Hofmeister V, Nischalke H-, Weiss E, Houghton M, Sauerbruch T, Spengler U. Binding of HCV E2 to CD81 enhances surface expression of HLA-E Journal of Hepatology. 38: 116. DOI: 10.1016/S0168-8278(03)80662-1 |
0.444 |
|
| 2002 |
Masciopinto F, Freer G, Burgio VL, Levy S, Galli-Stampino L, Bendinelli M, Houghton M, Abrignani S, Uematsu Y. Expression of human CD81 in transgenic mice does not confer susceptibility to hepatitis C virus infection. Virology. 304: 187-96. PMID 12504561 DOI: 10.1006/Viro.2002.1631 |
0.535 |
|
| 2002 |
Legrand E, Neau D, Galperine T, Trimoulet P, Moreau JF, Pitard V, Lacut JY, Ragnaud JM, Dupon M, Le Bail B, Bernard N, Schvoerer E, Houghton M, Fleury H, Lafon ME. CD4 T lymphocyte proliferative responses to hepatitis C virus (HCV) antigens in patients coinfected with HCV and human immunodeficiency virus who responded to anti-HCV treatment. The Journal of Infectious Diseases. 186: 302-11. PMID 12134226 DOI: 10.1086/341659 |
0.616 |
|
| 2001 |
Erickson AL, Kimura Y, Igarashi S, Eichelberger J, Houghton M, Sidney J, McKinney D, Sette A, Hughes AL, Walker CM. The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes. Immunity. 15: 883-95. PMID 11754811 DOI: 10.1016/S1074-7613(01)00245-X |
0.586 |
|
| 2001 |
Merola M, Brazzoli M, Cocchiarella F, Heile JM, Helenius A, Weiner AJ, Houghton M, Abrignani S. Folding of hepatitis C virus E1 glycoprotein in a cell-free system. Journal of Virology. 75: 11205-17. PMID 11602760 DOI: 10.1128/Jvi.75.22.11205-11217.2001 |
0.4 |
|
| 2001 |
Weiner AJ, Paliard X, Selby MJ, Medina-Selby A, Coit D, Nguyen S, Kansopon J, Arian CL, Ng P, Tucker J, Lee CT, Polakos NK, Han J, Wong S, Lu HH, ... ... Houghton M, et al. Intrahepatic genetic inoculation of hepatitis C virus RNA confers cross-protective immunity. Journal of Virology. 75: 7142-8. PMID 11435595 DOI: 10.1128/Jvi.75.15.7142-7148.2001 |
0.568 |
|
| 2001 |
Bassett SE, Guerra B, Brasky K, Miskovsky E, Houghton M, Klimpel GR, Lanford RE. Protective immune response to hepatitis C virus in chimpanzees rechallenged following clearance of primary infection Hepatology. 33: 1479-1487. PMID 11391537 DOI: 10.1053/Jhep.2001.24371 |
0.622 |
|
| 2001 |
Tseng CTK, Miskovsky E, Houghton M, Klimpel GR. Characterization of liver T-cell receptor γδ+ T cells obtained from individuals chronically infected with hepatitis C virus (HCV): Evidence for these T cells playing a role in the liver pathology associated with HCV infections Hepatology. 33: 1312-1320. PMID 11343261 DOI: 10.1053/Jhep.2001.24269 |
0.595 |
|
| 2001 |
Schirren CA, Jung MC, Worzfeld T, Mamin M, Baretton G, Gerlach JT, Gruener NH, Zachoval R, Houghton M, Rau HG, Pape GR. Hepatitis C virus-specific CD4+ T cell response after liver transplantation occurs early, is multispecific, compartmentalizes to the liver, and does not correlate with recurrent disease. The Journal of Infectious Diseases. 183: 1187-94. PMID 11262200 DOI: 10.1086/319692 |
0.581 |
|
| 2001 |
Polakos NK, Drane D, Cox J, Ng P, Selby MJ, Chien D, O'Hagan DT, Houghton M, Paliard X. Characterization of hepatitis C virus core-specific immune responses primed in rhesus macaques by a nonclassical ISCOM vaccine. Journal of Immunology (Baltimore, Md. : 1950). 166: 3589-98. PMID 11207320 DOI: 10.4049/Jimmunol.166.5.3589 |
0.514 |
|
| 2001 |
Schirren C, Gruener N, Jung M, Zachoval R, Gerlach J, Diepolder H, Houghton M, Rau H, Pape G. Hepatitis C virus (HCV)-specific CD8+ T cells in patients with recurrent HCV-infection after liver transplantation (OLTx) Journal of Hepatology. 34: 115. DOI: 10.1016/S0168-8278(01)81288-5 |
0.616 |
|
| 2001 |
Schirren CA, Zachoval R, Jung MC, Gerlach JT, Gruener N, Diepolder HM, Houghton M, Rau HG, Pape GR. Only a strong, multispecific, and longlasting CD4+ T cell response is associated with viral elimination in patients with recurrent HCV-infection after OLTx Journal of Hepatology. 34: 114. DOI: 10.1016/S0168-8278(01)81287-3 |
0.516 |
|
| 2000 |
Fan XG, Tang FQ, Yi H, Liu WE, Houghton M, Hu GL. Effect of IL-12 on T-cell immune responses in patients with chronic HCV infection. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 108: 531-8. PMID 11167550 DOI: 10.1034/J.1600-0463.2000.01087-8531.X |
0.546 |
|
| 2000 |
Alter HJ, Houghton M. Clinical Medical Research Award. Hepatitis C virus and eliminating post-transfusion hepatitis. Nature Medicine. 6: 1082-6. PMID 11017126 DOI: 10.1038/80394 |
0.501 |
|
| 2000 |
Allander T, Drakenberg K, Beyene A, Rosa D, Abrignani S, Houghton M, Widell A, Grillner L, Persson MAA. Recombinant human monoclonal antibodies against different conformational epitopes of the E2 envelope glycoprotein of hepatitis C virus that inhibit its interaction with CD81 Journal of General Virology. 81: 2451-2459. PMID 10993933 DOI: 10.1099/0022-1317-81-10-2451 |
0.522 |
|
| 2000 |
Schirren CA, Jung MC, Gerlach JT, Worzfeld T, Baretton G, Mamin M, Hubert Gruener N, Houghton M, Pape GR. Liver-derived hepatitis C virus (HCV)-specific CD4(+) T cells recognize multiple HCV epitopes and produce interferon gamma. Hepatology (Baltimore, Md.). 32: 597-603. PMID 10960455 DOI: 10.1053/Jhep.2000.9635 |
0.575 |
|
| 2000 |
Heile JM, Fong YL, Rosa D, Berger K, Saletti G, Campagnoli S, Bensi G, Capo S, Coates S, Crawford K, Dong C, Wininger M, Baker G, Cousens L, Chien D, ... ... Houghton M, et al. Evaluation of hepatitis C virus glycoprotein E2 for vaccine design: an endoplasmic reticulum-retained recombinant protein is superior to secreted recombinant protein and DNA-based vaccine candidates. Journal of Virology. 74: 6885-92. PMID 10888628 DOI: 10.1128/Jvi.74.15.6885-6892.2000 |
0.507 |
|
| 2000 |
Lee AY, Manning WC, Arian CL, Polakos NK, Barajas JL, Ulmer JB, Houghton M, Paliard X. Priming of hepatitis C virus-specific cytotoxic T lymphocytes in mice following portal vein injection of a liver-specific plasmid DNA. Hepatology (Baltimore, Md.). 31: 1327-33. PMID 10827159 DOI: 10.1053/Jhep.2000.7297 |
0.604 |
|
| 2000 |
Petracca R, Falugi F, Galli G, Norais N, Rosa D, Campagnoli S, Burgio V, Di Stasio E, Giardina B, Houghton M, Abrignani S, Grandi G. Structure-function analysis of hepatitis C virus envelope-CD81 binding. Journal of Virology. 74: 4824-30. PMID 10775621 DOI: 10.1128/Jvi.74.10.4824-4830.2000 |
0.521 |
|
| 2000 |
Lee AY, Polakos NK, Otten GR, Ulmer JB, Houghton M, Paliard X. Quantification of the number of cytotoxic T cells specific for an immunodominant HCV-specific CTL epitope primed by DNA immunization. Vaccine. 18: 1962-8. PMID 10699347 DOI: 10.1016/S0264-410X(99)00486-7 |
0.59 |
|
| 2000 |
Houghton M. Strategies and prospects for vaccination against the hepatitis C viruses. Current Topics in Microbiology and Immunology. 242: 327-39. PMID 10592667 DOI: 10.1007/978-3-642-59605-6_15 |
0.31 |
|
| 2000 |
Weiner AJ, Chien D, Choo Q, Coates SR, Kuo G, Houghton M. 7 Humoral response to hepatitis C virus Biomedical Research Reports. 2: 125-145. DOI: 10.1016/S1874-5326(00)80011-3 |
0.603 |
|
| 2000 |
Schirren CA, Jung MC, Worzfeld T, Gerlach JT, Gruener NH, Diepolder HM, Houghton M, Pape GR. Intrahepatic HCV-Specific CD4+ T cells in chronic HCV-infection are multispecific and produce γ-IFN Journal of Hepatology. 32: 33. DOI: 10.1016/S0168-8278(00)80461-4 |
0.569 |
|
| 1999 |
Weiner AJ, Calvo PL, Kansopon J, Gretch D, Bonino F, Brunetto M, Houghton M. Hepatitis C virus heteroduplex tracking assay : application to genotype determination, quasispecies analysis, and molecular evolution studies. Methods in Molecular Medicine. 19: 221-33. PMID 21374364 DOI: 10.1385/0-89603-521-2:221 |
0.305 |
|
| 1999 |
Hsu HH, Abrignani S, Houghton M. Prospects for a hepatitis C virus vaccine. Clinics in Liver Disease. 3: 901-15. PMID 11291258 DOI: 10.1016/S1089-3261(05)70246-4 |
0.537 |
|
| 1999 |
Abrignani S, Houghton M, Hsu HH. Perspectives for a vaccine against hepatitis C virus. Journal of Hepatology. 31: 259-63. PMID 10622599 DOI: 10.1016/S0168-8278(99)80413-9 |
0.582 |
|
| 1999 |
Colombatto P, Brunetto MR, Kansopon J, Oliveri F, Maina A, Aragon U, Bortoli ML, Scatena F, Baicchi U, Houghton M, Bonino F, Weiner AJ. High prevalence of G1 and G2 TT-virus infection in subjects with high and low blood exposure risk: identification of G4 isolates in Italy. Journal of Hepatology. 31: 990-6. PMID 10604571 DOI: 10.1016/S0168-8278(99)80310-9 |
0.403 |
|
| 1999 |
Rosen HR, Hinrichs DJ, Gretch DR, Koziel MJ, Chou S, Houghton M, Rabkin J, Corless CL, Bouwer HG. Association of multispecific CD4(+) response to hepatitis C and severity of recurrence after liver transplantation. Gastroenterology. 117: 926-32. PMID 10500076 DOI: 10.1016/S0016-5085(99)70352-5 |
0.422 |
|
| 1999 |
Mustilli AC, Izzo E, Houghton M, Galeotti CL. Comparison of secretion of a hepatitis C virus glycoprotein in Saccharomyces cerevisiae and Kluyveromyces lactis. Research in Microbiology. 150: 179-87. PMID 10229947 DOI: 10.1016/s0923-2508(99)80034-5 |
0.404 |
|
| 1999 |
Cooper S, Erickson AL, Adams EJ, Kansopon J, Weiner AJ, Chien DY, Houghton M, Parham P, Walker CM. Analysis of a successful immune response against hepatitis C virus Immunity. 10: 439-449. PMID 10229187 DOI: 10.1016/S1074-7613(00)80044-8 |
0.586 |
|
| 1999 |
Liberman E, Fong YL, Selby MJ, Choo QL, Cousens L, Houghton M, Yen TS. Activation of the grp78 and grp94 promoters by hepatitis C virus E2 envelope protein. Journal of Virology. 73: 3718-22. PMID 10196264 DOI: 10.1128/Jvi.73.5.3718-3722.1999 |
0.367 |
|
| 1998 |
Pileri P, Uematsu Y, Campagnoli S, Galli G, Falugi F, Petracca R, Weiner AJ, Houghton M, Rosa D, Grandi G, Abrignani S. Binding of hepatitis C virus to CD81. Science (New York, N.Y.). 282: 938-41. PMID 9794763 DOI: 10.1126/Science.282.5390.938 |
0.616 |
|
| 1998 |
Ishii K, Rosa D, Watanabe Y, Katayama T, Harada H, Wyatt C, Kiyosawa K, Aizaki H, Matsuura Y, Houghton M, Abrignani S, Miyamura T. High titers of antibodies inhibiting the binding of envelope to human cells correlate with natural resolution of chronic hepatitis C. Hepatology (Baltimore, Md.). 28: 1117-20. PMID 9755251 DOI: 10.1002/Hep.510280429 |
0.59 |
|
| 1998 |
Accapezzato D, Nisini R, Paroli M, Bruno G, Bonino F, Houghton M, Barnaba V. Generation of an MHC class II-restricted T cell epitope by extracellular processing of hepatitis delta antigen. Journal of Immunology (Baltimore, Md. : 1950). 160: 5262-6. PMID 9605122 |
0.383 |
|
| 1998 |
Wong DK, Dudley DD, Afdhal NH, Dienstag J, Rice CM, Wang L, Houghton M, Walker BD, Koziel MJ. Liver-derived CTL in hepatitis C virus infection: breadth and specificity of responses in a cohort of persons with chronic infection. Journal of Immunology (Baltimore, Md. : 1950). 160: 1479-88. PMID 9570570 |
0.518 |
|
| 1998 |
Calvo PL, Kansopon J, Sra K, Quan S, DiNello R, Guaschino R, Calabrese G, Danielle F, Brunetto MR, Bonino F, Massaro AL, Polito A, Houghton M, Weiner AJ. Hepatitis C virus heteroduplex tracking assay for genotype determination reveals diverging genotype 2 isolates in Italian hemodialysis patients. Journal of Clinical Microbiology. 36: 227-33. PMID 9431953 DOI: 10.1128/Jcm.36.1.227-233.1998 |
0.489 |
|
| 1998 |
Gerlach JT, Diepolder HM, Grüner NH, Jung MC, Zachoval R, Hoffmann R, Schirren CA, Schraut W, Santantonio T, Houghton M, Pape GR. Recurrence of hepatitis C virus after loss of virus specific CD4+ T cell response in acute hepatitis C Journal of Hepatology. 28: 44. DOI: 10.1016/S0168-8278(98)80385-1 |
0.515 |
|
| 1998 |
Schirren C, Jung M, Worzfeld T, Mamin M, Gerlach J, Grüner N, Hoffmann R, Diepolder H, Zachoval R, Houghton M, Pape G. Response of T cells from HCV reinfected grafts after LTX resembles that of T cells from peripheral blood in acute hepatitis C Journal of Hepatology. 28: 43. DOI: 10.1016/S0168-8278(98)80383-8 |
0.509 |
|
| 1997 |
Koziel MJ, Wong DKH, Dudley D, Houghton M, Walker BD. Hepatitis C virus - Specific cytolytic T lymphocyte and T helper cell responses in seronegative persons Journal of Infectious Diseases. 176: 859-866. PMID 9333142 DOI: 10.1086/516546 |
0.614 |
|
| 1997 |
Missale G, Cariani E, Lamonaca V, Ravaggi A, Rossini A, Bertoni R, Houghton M, Matsuura Y, Miyamura T, Fiaccadori F, Ferrari C. Effects of interferon treatment on the antiviral T-cell response in hepatitis C virus genotype 1b- and genotype 2c-infected patients. Hepatology (Baltimore, Md.). 26: 792-7. PMID 9303515 DOI: 10.1053/jhep.1997.v26.pm0009303515 |
0.519 |
|
| 1997 |
Diepolder HM, Gerlach JT, Zachoval R, Hoffmann RM, Jung MC, Wierenga EA, Scholz S, Santantonio T, Houghton M, Southwood S, Sette A, Pape GR. Immunodominant CD4+ T-cell epitope within nonstructural protein 3 in acute hepatitis C virus infection. Journal of Virology. 71: 6011-9. PMID 9223492 DOI: 10.1128/Jvi.71.8.6011-6019.1997 |
0.471 |
|
| 1997 |
Pasquinelli C, Shoenberger JM, Chung J, Chang KMI, Guidotti LG, Selby M, Berger K, Lesniewski R, Houghton M, Chisari FV. Hepatitis C virus core and E2 protein expression in transgenic mice Hepatology. 25: 719-727. PMID 9049225 DOI: 10.1002/Hep.510250338 |
0.511 |
|
| 1997 |
Nisini R, Paroli M, Accapezzato D, Bonino F, Rosina F, Santantonio T, Sallusto F, Amoroso A, Houghton M, Barnaba V. Human CD4+ T-cell response to hepatitis delta virus: identification of multiple epitopes and characterization of T-helper cytokine profiles. Journal of Virology. 71: 2241-51. PMID 9032359 DOI: 10.1128/Jvi.71.3.2241-2251.1997 |
0.428 |
|
| 1997 |
Nelson DR, Marousis CG, Davis GL, Rice CM, Wong J, Houghton M, Lau JY. The role of hepatitis C virus-specific cytotoxic T lymphocytes in chronic hepatitis C. Journal of Immunology (Baltimore, Md. : 1950). 158: 1473-81. PMID 9013994 |
0.56 |
|
| 1996 |
Piazza M, Chien D, Quan S, Houghton M. Lack of antibodies to the envelope glycoproteins of hepatitis C virus in immunoglobulin preparations from screened donors. Bollettino Della Società Italiana Di Biologia Sperimentale. 72: 69-70. PMID 8868116 |
0.374 |
|
| 1996 |
Rehermann B, Chang KM, McHutchison JG, Kokka R, Houghton M, Chisari FV. Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection Journal of Clinical Investigation. 98: 1432-1440. PMID 8823309 DOI: 10.1172/Jci118931 |
0.604 |
|
| 1996 |
Rehermann B, Chang KM, McHutchison J, Kokka R, Houghton M, Rice CM, Chisari FV. Differential cytotoxic T-lymphocyte responsiveness to the hepatitis B and C viruses in chronically infected patients Journal of Virology. 70: 7092-7102. PMID 8794355 DOI: 10.1128/Jvi.70.10.7092-7102.1996 |
0.618 |
|
| 1996 |
Rosa D, Campagnoli S, Moretto C, Guenzi E, Cousens L, Chin M, Dong C, Weiner AJ, Lau JY, Choo QL, Chien D, Pileri P, Houghton M, Abrignani S. A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 1759-63. PMID 8700831 DOI: 10.1073/Pnas.93.5.1759 |
0.594 |
|
| 1996 |
Missale G, Bertoni R, Lamonaca V, Valli A, Massari M, Mori C, Rumi MG, Houghton M, Fiaccadori F, Ferrari C. Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response. The Journal of Clinical Investigation. 98: 706-14. PMID 8698862 DOI: 10.1172/Jci118842 |
0.534 |
|
| 1995 |
Yoo BJ, Selby MJ, Choe J, Suh BS, Choi SH, Joh JS, Nuovo GJ, Lee HS, Houghton M, Han JH. Transfection of a differentiated human hepatoma cell line (Huh7) with in vitro-transcribed hepatitis C virus (HCV) RNA and establishment of a long-term culture persistently infected with HCV. Journal of Virology. 69: 32-8. PMID 7983724 DOI: 10.1128/Jvi.69.1.32-38.1995 |
0.601 |
|
| 1995 |
Cerny A, Fowler P, Brothers MA, Houghton M, Schlicht HJ, Chisari FV. Induction in vitro of a primary human antiviral cytotoxic T cell response. European Journal of Immunology. 25: 627-30. PMID 7875224 DOI: 10.1002/Eji.1830250248 |
0.409 |
|
| 1995 |
Cerny A, McHutchison JG, Pasquinelli C, Brown ME, Brothers MA, Grabscheid B, Fowler P, Houghton M, Chisari FV. Cytotoxic T lymphocyte response to hepatitis C virus-derived peptides containing the HLA A2.1 binding motif. The Journal of Clinical Investigation. 95: 521-30. PMID 7860734 DOI: 10.1172/Jci117694 |
0.588 |
|
| 1995 |
Weiner A, Erickson AL, Kansopon J, Crawford K, Muchmore E, Hughes AL, Houghton M, Walker CM. Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant. Proceedings of the National Academy of Sciences of the United States of America. 92: 2755-9. PMID 7708719 DOI: 10.1073/Pnas.92.7.2755 |
0.637 |
|
| 1995 |
Lagging LM, Meyer K, Hoft D, Houghton M, Belshe RB, Ray R. Immune responses to plasmid DNA encoding the hepatitis C virus core protein. Journal of Virology. 69: 5859-63. PMID 7637033 DOI: 10.1128/Jvi.69.9.5859-5863.1995 |
0.62 |
|
| 1995 |
Koziel MJ, Dudley D, Afdhal N, Grakoui A, Rice CM, Choo QL, Houghton M, Walker BD. HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus: Identification of multiple epitopes and characterization of patterns of cytokine release Journal of Clinical Investigation. 96: 2311-2321. PMID 7593618 DOI: 10.1172/Jci118287 |
0.596 |
|
| 1994 |
Ray R, Khanna A, Lagging LM, Meyer K, Choo QL, Ralston R, Houghton M, Becherer PR. Peptide immunogen mimicry of putative E1 glycoprotein-specific epitopes in hepatitis C virus. Journal of Virology. 68: 4420-6. PMID 8207814 DOI: 10.1128/Jvi.68.7.4420-4426.1994 |
0.582 |
|
| 1994 |
Selby MJ, Glazer E, Masiarz F, Houghton M. Complex processing and protein:protein interactions in the E2:NS2 region of HCV. Virology. 204: 114-22. PMID 8091646 DOI: 10.1006/Viro.1994.1515 |
0.47 |
|
| 1994 |
Houghton M, Selby M, Weiner A, Choo Q. Hepatitis C Virus: Structure, Protein Products and Processing of the Polyprotein Precursor Current Studies in Hematology and Blood Transfusion. 61: 1-11. PMID 7956324 DOI: 10.1159/000423264 |
0.462 |
|
| 1994 |
Saracco G, Abate ML, Baldi M, Calvo PL, Manzini P, Brunetto MR, Oliveri F, Kuo G, Chien D, Houghton M. Hepatitis C virus markers in patients with long-term biochemical and histological remission of chronic hepatitis. Liver. 14: 65-70. PMID 7515141 DOI: 10.1111/J.1600-0676.1994.Tb00049.X |
0.568 |
|
| 1994 |
Simmonds P, Alberti A, Alter HJ, Bonino F, Bradley DW, Brechot C, Brouwer JT, Chan SW, Chayama K, Chen DS, Choo QL, Colombo M, Cuypers HTM, Date T, Dusheiko GM, ... ... Houghton M, et al. A proposed system for the nomenclature of hepatitis C viral genotypes Hepatology. 19: 1321-1324. DOI: 10.1002/Hep.1840190538 |
0.533 |
|
| 1993 |
Botarelli P, Brunetto MR, Minutello MA, Calvo P, Unutmaz D, Weiner AJ, Choo Ql, Shuster JR, Kuo G, Bonino F, Houghton M, Abrignam S. T-lymphocyte response to hepatitis C virus in different clinical courses of infection Gastroenterology. 104: 580-587. PMID 8425701 DOI: 10.1016/0016-5085(93)90430-K |
0.545 |
|
| 1993 |
Ralston R, Thudium K, Berger K, Kuo C, Gervase B, Hall J, Selby M, Kuo G, Houghton M, Choo QL. Characterization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia viruses. Journal of Virology. 67: 6753-61. PMID 8411378 DOI: 10.1128/Jvi.67.11.6753-6761.1993 |
0.495 |
|
| 1993 |
Bresters D, Mauser-Bunschoten EP, Cuypers HT, Han JH, Jansen PL, Chamuleau RA, Houghton M, Reesink HW. Long term treatment of chronic hepatitis C with interferon alfa-2b: disappearance of HCV-RNA in a pilot study of eight haemophilia patients. Gut. 34: S124-5. PMID 8390953 DOI: 10.1136/Gut.34.2_Suppl.S124 |
0.522 |
|
| 1993 |
Weiner AJ, Thaler MM, Crawford K, Ching K, Kansopon J, Chien DY, Hall JE, Hu F, Houghton M. A unique, predominant hepatitis C virus variant found in an infant born to a mother with multiple variants. Journal of Virology. 67: 4365-8. PMID 8389933 DOI: 10.1128/Jvi.67.7.4365-4368.1993 |
0.468 |
|
| 1993 |
Selby MJ, Choo QL, Berger K, Kuo G, Glazer E, Eckart M, Lee C, Chien D, Kuo C, Houghton M. Expression, identification and subcellular localization of the proteins encoded by the hepatitis C viral genome. The Journal of General Virology. 74: 1103-13. PMID 8389800 DOI: 10.1099/0022-1317-74-6-1103 |
0.559 |
|
| 1993 |
Eckart MR, Selby M, Masiarz F, Lee C, Berger K, Crawford K, Kuo C, Kuo G, Houghton M, Choo QL. The hepatitis C virus encodes a serine protease involved in processing of the putative nonstructural proteins from the viral polyprotein precursor. Biochemical and Biophysical Research Communications. 192: 399-406. PMID 8387277 DOI: 10.1006/Bbrc.1993.1429 |
0.574 |
|
| 1993 |
Minutello MA, Pileri P, Unutmaz D, Censini S, Kuo G, Houghton M, Brunetto MR, Bonino F, Abrignani S. Compartmentalization of T lymphocytes to the site of disease: intrahepatic CD4+ T cells specific for the protein NS4 of hepatitis C virus in patients with chronic hepatitis C. The Journal of Experimental Medicine. 178: 17-25. PMID 8100267 DOI: 10.1084/Jem.178.1.17 |
0.482 |
|
| 1993 |
Koziel MJ, Dudley D, Afdhal N, Choo QL, Houghton M, Ralston R, Walker BD. Hepatitis C virus (HCV)-specific cytotoxic T lymphocytes recognize epitopes in the core and envelope proteins of HCV Journal of Virology. 67: 7522-7532. PMID 7693974 DOI: 10.1128/Jvi.67.12.7522-7532.1993 |
0.653 |
|
| 1993 |
Cuypers HT, Bresters D, Winkel IN, Reesink HW, Weiner AJ, Houghton M, van der Poel CL, Lelie PN. Storage conditions of blood samples and primer selection affect the yield of cDNA polymerase chain reaction products of hepatitis C virus. Journal of Clinical Microbiology. 30: 3220-4. PMID 1333489 DOI: 10.1128/Jcm.30.12.3220-3224.1992 |
0.523 |
|
| 1993 |
CHIEN DY, CHOO Q, TABRIZI A, KUO C, McFARLAND J, BERGER K, LEE C, SHUSTER JR, NGUYEN T, MOYER DL, TONG M, FURUTA S, OMATA M, FONG CT, TEGTMEIER G, ... ... HOUGHTON M, et al. Use of recombinant HCV antigen in the serodiagnosis of hepatitis C virus infection: Significant improvement in HCV antibody detection as compared with the first generation HCV C100-3 ELISA and the synthetic peptide EIA tests Journal of Gastroenterology and Hepatology. 8: S33-S39. DOI: 10.1111/J.1440-1746.1993.Tb01679.X |
0.57 |
|
| 1993 |
Saracco G, Rosina F, Abate ML, Chiandussi L, Gallo V, Cerutti E, Napoli AD, Solinas A, Deplano A, Tocco A, Cossu P, Chien D, Kuo G, Polito A, Weiner AJ, ... Houghton M, et al. Long-term follow-up of patients with chronic hepatitis C treated with different doses of interferon-α2b Hepatology. 18: 1300-1305. DOI: 10.1002/Hep.1840180603 |
0.458 |
|
| 1992 |
Cuypers HT, Winkel IN, van der Poel CL, Reesink HW, Lelie PN, Houghton M, Weiner A. Analysis of genomic variability of hepatitis C virus. Journal of Hepatology. S15-9. PMID 1668327 DOI: 10.1016/0168-8278(91)90016-5 |
0.618 |
|
| 1992 |
Bresters D, Cuypers HT, Reesink HW, Schaasberg WP, van der Poel CL, Mauser-Bunschoten EP, Houghton M, Choo QL, Kuo G, Lesniewski R. Enhanced sensitivity of a second generation ELISA for antibody to hepatitis C virus. Vox Sanguinis. 62: 213-7. PMID 1379394 DOI: 10.1111/J.1423-0410.1992.Tb01201.X |
0.596 |
|
| 1992 |
Krawczynski K, Beach MJ, Bradley DW, Kuo G, Di Bisceglie AM, Houghton M, Reyes GR, Kim JP, Choo QL, Alter MJ. Hepatitis C virus antigen in hepatocytes: Immunomorphologic detection and identification Gastroenterology. 103: 622-629. PMID 1378804 DOI: 10.1016/0016-5085(92)90856-T |
0.639 |
|
| 1992 |
Choo QL, Kuo G, Weiner A, Wang KS, Overby L, Bradley D, Houghton M. Identification of the major, parenteral non-A, non-B hepatitis agent (hepatitis C virus) using a recombinant cDNA approach. Seminars in Liver Disease. 12: 279-88. PMID 1332193 DOI: 10.1055/S-2007-1007399 |
0.515 |
|
| 1992 |
Bresters D, Mauser-Bunschoten EP, Cuypers HT, Lelie PN, Han JH, Jansen PL, Houghton M, Reesink HW. Disappearance of hepatitis C virus RNA in plasma during interferon alpha-2B treatment in hemophilia patients. Scandinavian Journal of Gastroenterology. 27: 166-8. PMID 1323873 DOI: 10.3109/00365529208999943 |
0.522 |
|
| 1992 |
van der Poel CL, Bresters D, Reesink HW, Plaisier AA, Schaasberg W, Leentvaar-Kuypers A, Choo QL, Quan S, Polito A, Houghton M. Early antihepatitis C virus response with second-generation C200/C22 ELISA. Vox Sanguinis. 62: 208-12. PMID 1322611 DOI: 10.1111/J.1423-0410.1992.Tb01200.X |
0.579 |
|
| 1992 |
Han JH, Houghton M. Group specific sequences and conserved secondary structures at the 3' end of HCV genome and its implication for viral replication. Nucleic Acids Research. 20: 3520. PMID 1321416 DOI: 10.1093/Nar/20.13.3520 |
0.497 |
|
| 1992 |
Spaete RR, Alexander D, Rugroden ME, Choo Q, Berger K, Crawford K, Kuo C, Leng S, Lee C, Ralston R, Thudium K, Tung JW, Kuo G, Houghton M. Characterization of the hepatitis C virus E2/NS1 gene product expressed in mammalian cells. Virology. 188: 819-830. PMID 1316682 DOI: 10.1016/0042-6822(92)90537-Y |
0.454 |
|
| 1992 |
Jeffers LJ, Hasan F, Medina Md, Reddy R, Parker T, Silva M, Mendez L, Schiff ER, Manns M, Houghton M, Choo Q‐, Kuo G. Prevalence of antibodies to hepatitis C virus among patients with cryptogenic chronic hepatitis and cirrhosis Hepatology. 15: 187-190. PMID 1310475 DOI: 10.1002/Hep.1840150204 |
0.564 |
|
| 1992 |
Yoo BJ, Spaete RR, Geballe AP, Selby M, Houghton M, Han JH. 5′ end-dependent translation initiation of hepatitis C viral RNA and the presence of putative positive and negative translational control elements within the 5′ untranslated region Virology. 191: 889-899. PMID 1280383 DOI: 10.1016/0042-6822(92)90264-P |
0.547 |
|
| 1992 |
THALER MM, PARK C, LANDERS DV, WARA DW, HOUGHTON M, VEEREMAN-WAUTERS G, SWEET RL, HAN JH. Vertical Transmission of Hepatitis C Virus Obstetrical & Gynecological Survey. 47: 31-32. DOI: 10.1097/00006254-199201000-00012 |
0.515 |
|
| 1991 |
Takeuchi K, Kubo Y, Boonmar S, Watanabe Y, Katayama T, Choo QL, Kuo G, Houghton M, Saito I, Miyamura T. The putative nucleocapsid and envelope protein genes of hepatitis C virus determined by comparison of the nucleotide sequences of two isolates derived from an experimentally infected chimpanzee and healthy human carriers. The Journal of General Virology. 3027-33. PMID 2177094 DOI: 10.1099/0022-1317-71-12-3027 |
0.525 |
|
| 1991 |
Katkov WN, Friedman LS, Cody H, Evans A, Kuo G, Choo Q, Houghton M, Dienstag JL. Elevated serum alanine aminotransferase levels in blood donors: the contribution of hepatitis C virus. Annals of Internal Medicine. 115: 882-884. PMID 1952477 DOI: 10.7326/0003-4819-115-11-882 |
0.583 |
|
| 1991 |
Weiner AJ, Brauer MJ, Rosenblatt J, Richman KH, Tung J, Crawford K, Bonino F, Saracco G, Choo QL, Houghton M. Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins. Virology. 180: 842-8. PMID 1846505 DOI: 10.1016/0042-6822(91)90104-J |
0.518 |
|
| 1991 |
Rosina F, Fabiano A, Garripoli A, Smedile A, Mattalia A, Eckart MR, Houghton M, Ferruccio B. Rabbit-derived anti-HD antibodies for HDAg immunoblotting. Journal of Hepatology. 13. PMID 1822507 DOI: 10.1016/0168-8278(91)90044-C |
0.323 |
|
| 1991 |
Magrin S, Craxi A, Fabiano C, Fiorentino G, Almasio P, Palazzo U, Pinzello G, Provenzano G, Pagliaro L, Choo Q, Kuo G, Polito A, Han J, Houghton M. Hepatitis C virus replication in ‘autoimmune’ chronic hepatitis Journal of Hepatology. 13: 364-367. PMID 1725529 DOI: 10.1016/0168-8278(91)90082-M |
0.615 |
|
| 1991 |
Han JH, Shyamala V, Richman KH, Brauer MJ, Irvine B, Urdea MS, Tekamp-Olson P, Kuo G, Choo QL, Houghton M. Characterization of the terminal regions of hepatitis C viral RNA: identification of conserved sequences in the 5' untranslated region and poly(A) tails at the 3' end. Proceedings of the National Academy of Sciences of the United States of America. 88: 1711-5. PMID 1705704 DOI: 10.1073/Pnas.88.5.1711 |
0.558 |
|
| 1991 |
Poel CLvd, Reesink HW, Boven JJPv, Cuypers HTM, Winkel I, Exel-Oehlers PJ, Schaasberg W, Lelie PN, Weiner AJ, Polito A, Quan S, Nello RD, Houghton M, Mulder-Folkerts D, Leentvaar-Kuypers A. Confirmation of hepatitis C virus infection by new four-antigen recombinant immunoblot assay. The Lancet. 337: 317-319. PMID 1671231 DOI: 10.1016/0140-6736(91)90942-I |
0.559 |
|
| 1991 |
Cha TA, Kolberg J, Irvine B, Stempien M, Beall E, Yano M, Choo QL, Houghton M, Kuo G, Han JH. Use of a signature nucleotide sequence of hepatitis C virus for detection of viral RNA in human serum and plasma. Journal of Clinical Microbiology. 29: 2528-34. PMID 1663510 DOI: 10.1128/Jcm.29.11.2528-2534.1991 |
0.582 |
|
| 1991 |
McHutchison JG, Kuo G, Houghton M, Choo QL, Redeker AG. Hepatitis C virus antibodies in acute icteric and chronic non-A, non-B hepatitis. Gastroenterology. 101: 1117-9. PMID 1653749 DOI: 10.1016/0016-5085(91)90742-4 |
0.416 |
|
| 1991 |
Katkov WN, Dienstag JL, Cody H, Evans AA, Choo QL, Houghton M, Kuo G. Role of hepatitis C virus in non-B chronic liver disease. Archives of Internal Medicine. 151: 1548-52. PMID 1651689 DOI: 10.1001/Archinte.1991.00400080054009 |
0.502 |
|
| 1991 |
Houghton M, Weiner A, Han J, Kuo G, Choo Q. Molecular biology of the hepatitis C viruses: Implications for diagnosis, development and control of viral disease Hepatology. 14: 381-388. DOI: 10.1002/Hep.1840140227 |
0.437 |
|
| 1990 |
Kubo Y, Takeuchi K, Boonmar S, Katayama T, Choo QL, Kuo G, Weiner AJ, Bradley DW, Houghton M, Saito I. A cDNA fragment of hepatitis C virus isolated from an implicated donor of post-transfusion non-A, non-B hepatitis in Japan. Nucleic Acids Research. 17: 10367-72. PMID 2513560 DOI: 10.1093/Nar/17.24.10367 |
0.619 |
|
| 1990 |
Takeuchi K, Boonmar S, Kubo Y, Katayama T, Harada H, Ohbayashi A, Choo QL, Kuo G, Houghton M, Saito I. Hepatitis C viral cDNA clones isolated from a healthy carrier donor implicated in post-transfusion non-A, non-B hepatitis. Gene. 91: 287-91. PMID 2170237 DOI: 10.1016/0378-1119(90)90102-W |
0.624 |
|
| 1990 |
Chen D, Kuo GC, Sung J, Lai M, Sheu J, Chen P, Yang P, Hsu H, Chang M, Chen C, Hahn L, Choo Q, Wang T, Houghton M. Hepatitis C Virus Infection in an Area Hyperendemic for Hepatitis B and Chronic Liver Disease: The Taiwan Experience The Journal of Infectious Diseases. 162: 817-822. PMID 2169497 DOI: 10.1093/Infdis/162.4.817 |
0.609 |
|
| 1990 |
Hasan F, Jeffers LJ, Medina MD, Reddy KR, Parker T, FACPERSMD, Houghton M, Choo Q, Kuo G. Hepatitis C–associated hepatocellular carcinoma Hepatology. 12: 589-591. PMID 2169456 DOI: 10.1002/Hep.1840120323 |
0.473 |
|
| 1990 |
Takeuchi K, Kubo Y, Boonmar S, Watanabe Y, Katayama T, Choo QL, Kuo G, Houghton M, Saito I, Miyamura T. Nucleotide sequence of core and envelope genes of the hepatitis C virus genome derived directly from human healthy carriers. Nucleic Acids Research. 18: 4626. PMID 2117749 DOI: 10.1093/Nar/18.15.4626 |
0.44 |
|
| 1990 |
Shimizu YK, Weiner AJ, Rosenblatt J, Wong DC, Shapiro M, Popkin T, Houghton M, Alter HJ, Purcell RH. Early events in hepatitis C virus infection of chimpanzees. Proceedings of the National Academy of Sciences of the United States of America. 87: 6441-4. PMID 2117282 DOI: 10.1073/Pnas.87.16.6441 |
0.62 |
|
| 1990 |
Choo QL, Weiner AJ, Overby LR, Kuo G, Houghton M, Bradley DW. Hepatitis C virus: the major causative agent of viral non-A, non-B hepatitis. British Medical Bulletin. 46: 423-41. PMID 2116212 DOI: 10.1093/OXFORDJOURNALS.BMB.A072408 |
0.514 |
|
| 1990 |
Katayama T, Kikuchi S, Tanaka Y, Saito I, Miyamura T, Choo QL, Houghton M, Kuo G. Blood screening for non-A, non-B hepatitis by hepatitis C virus antibody assay. Transfusion. 30: 374-6. PMID 2112278 DOI: 10.1046/J.1537-2995.1990.30490273448.X |
0.605 |
|
| 1990 |
Miyamura T, Saito I, Katayama T, Kikuchi S, Tateda A, Houghton M, Choo QL, Kuo G. Detection of antibody against antigen expressed by molecularly cloned hepatitis C virus cDNA: application to diagnosis and blood screening for posttransfusion hepatitis. Proceedings of the National Academy of Sciences of the United States of America. 87: 983-7. PMID 2105505 DOI: 10.1073/Pnas.87.3.983 |
0.483 |
|
| 1990 |
Stevens CE, Taylor PE, Pindyck J, Choo QL, Bradley DW, Kuo G, Houghton M. Epidemiology of hepatitis C virus. A preliminary study in volunteer blood donors. Jama. 263: 49-53. PMID 2104548 DOI: 10.1001/Jama.1990.03440010047028 |
0.574 |
|
| 1990 |
Weiner A, Truett M, Han J, Polito A, Choo QL, Rosenblatt J, Quan S, Kuo G, Houghton M, Page E, Agius C, Nelles M. HCV testing in low-risk population The Lancet. 336: 695. PMID 1975884 DOI: 10.1016/0140-6736(90)92194-M |
0.47 |
|
| 1990 |
Makris M, Preston FE, Triger DR, Underwood JCE, Choo QL, Kuo G, Houghton M. Hepatitis C antibody and chronic liver disease in haemophilia The Lancet. 335: 1117-1119. PMID 1971863 DOI: 10.1016/0140-6736(90)91124-S |
0.605 |
|
| 1990 |
Weiner AJ, Kuo G, Lee C, Rosenblatt J, Choo QL, Houghton M, Bradley DW, Bonnino F, Saracco G. Detection of hepatitis C viral sequences in non-A, non-B hepatitis. The Lancet. 335: 1-3. PMID 1967327 DOI: 10.1016/0140-6736(90)90134-Q |
0.612 |
|
| 1990 |
Kew MC, Houghton M, Choo QL, Kuo G. Hepatitis C virus antibodies in southern African blacks with hepatocellular carcinoma The Lancet. 335: 873-874. PMID 1691422 DOI: 10.1016/0140-6736(90)90474-J |
0.603 |
|
| 1990 |
Magrin S, Craxi A, Almasio P, Fabiano C, Fiorentino G, Palazzo U, Pinzello G, Provenzeno G, Pagliaro L, Houghton M, Han J. HCV deffection in “autonimine” chronic active hepatitis Journal of Hepatology. 11: S99. DOI: 10.1016/0168-8278(90)91728-F |
0.579 |
|
| 1990 |
Kremsdorf D, Thiers V, Carreau F, Duclos H, Porchon C, Houghton M, Tiollais P, Bréchot C, Necker C. Cloning and sequence analysis of hepatitis B virus variants in “non a non B” infections Journal of Hepatology. 11: S36. DOI: 10.1016/0168-8278(90)91478-F |
0.356 |
|
| 1990 |
Mosley JW, Aach RD, Hollinger FB, Stevens CE, Barbosa LH, Nemo GJ, Holland PV, Bancroft WH, Zimmerman HJ, Kuo G, Choo Q, Houghton M. Non-A, non-B hepatitis and antibody to hepatitis C virus. Jama. 263: 77-78. DOI: 10.1001/Jama.1990.03440010075034 |
0.63 |
|
| 1989 |
Colombo M, Choo QL, Ninno ED, Dioguardi N, Kuo G, Donato MF, Tommasini MA, Houghton M. Prevalence Of Antibodies To Hepatitis C Virus In Italian Patients With Hepatocellular Carcinoma The Lancet. 334: 1006-1008. PMID 2572740 DOI: 10.1016/S0140-6736(89)91016-7 |
0.584 |
|
| 1989 |
Kamitsukasa H, Harada H, Yakura M, Fukuda A, Ohbayashi A, Saito I, Miyamura T, Choo Q, Houghton M, Kuo G. Intrafamilial transmission of hepatitis C virus. The Lancet. 334: 987. PMID 2571901 DOI: 10.1016/S0140-6736(89)91000-3 |
0.517 |
|
| 1989 |
Poel CLVD, Lelie PN, Choo Q, Reesink HW, Vaar-Kuypers AL, Kuo G, Houghton M. Anti-Hepatitis C Antibodies And Non-A, Non-B Post-Transfusion Hepatitis In The Netherlands The Lancet. 334: 297-298. PMID 2569103 DOI: 10.1016/S0140-6736(89)90486-8 |
0.528 |
|
| 1989 |
Esteban JI, Viladomiu L, Gonzalez A, Roget M, Genescà J, Esteban R, López-Talavera JC, Hernández JM, Vargas V, Buti M, Guardia J, Houghton M, Choo Q, Kuo G. Hepatitis C virus antibodies among risk groups in Spain. The Lancet. 334: 294-297. PMID 2569102 DOI: 10.1016/S0140-6736(89)90485-6 |
0.602 |
|
| 1989 |
Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science (New York, N.Y.). 244: 359-62. PMID 2523562 DOI: 10.1126/Science.2523562 |
0.376 |
|
| 1989 |
Alter HJ, Purcell RH, Shih JW, Melpolder JC, Houghton M, Choo QL, Kuo G. Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. The New England Journal of Medicine. 321: 1494-500. PMID 2509915 DOI: 10.1056/Nejm198911303212202 |
0.6 |
|
| 1989 |
Viladomiu L, Esteban J, González A, Lavera JL, Sánchez C, Quer J, Caragol I, Hernández J, Esteban R, Guardia J, Kuo G, Houghton M. Efficacy of alfa-interferon to prevent chronicity in patients with acute postransfusion non-A non-B hepatitis: A randimized, controlled trial Journal of Hepatology. 9: S241. DOI: 10.1016/0168-8278(89)90657-0 |
0.371 |
|
| 1989 |
Saracco G, Houghton M, Kuo G, Choo Q, Rosina F, Lattore V, Cerenzia M, Chiandussi L, Bonino F, Rizzetto M. Anti-hepatitis C virus in nonAnonB patients responding and non-responding to alpha-2A interferon Journal of Hepatology. 9: S219. DOI: 10.1016/0168-8278(89)90612-0 |
0.462 |
|
| 1989 |
Agius C, Garcia G, Tupper B, Malka E, Schroer D, Le A, Kranledat P, Nelles M, Dinello R, Quan S, Chien D, Polito A, Choo Q, Kuo G, Houghton M. Enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies to hepatitis C (non-A, non-B hepatitis) virus Journal of Hepatology. 9: S187. DOI: 10.1016/0168-8278(89)90550-3 |
0.503 |
|
| 1989 |
López-Talavera J, Esteban J, Viladomiu L, Hernández J, Vargas V, Roget M, González A, Buti M, Esteban R, Guardia J, Kuo G, Houghton M. Prevalence of circulating antibodies against the hepatitis C virus among different risk groups in Spain Journal of Hepatology. 9. DOI: 10.1016/0168-8278(89)90290-0 |
0.467 |
|
| 1989 |
Colombo M, Kuo G, Choo L, Houghton M, Tommasini M, Rumi M, Dioguardi M, Donato M, Del Ninno E. High prevalence of antibody to hepatitis C virus in patients with hepatocellular carcinoma (HCC) Journal of Hepatology. 9: S20. DOI: 10.1016/0168-8278(89)90216-X |
0.396 |
|
| 1988 |
Weiner AJ, Choo QL, Wang KS, Govindarajan S, Redeker AG, Gerin JL, Houghton M. A single antigenomic open reading frame of the hepatitis delta virus encodes the epitope(s) of both hepatitis delta antigen polypeptides p24 delta and p27 delta. Journal of Virology. 62: 594-9. PMID 2447291 DOI: 10.1128/Jvi.62.2.594-599.1988 |
0.481 |
|
| 1987 |
Weiner AJ, Wang KS, Choo QL, Gerin JL, Bradley DW, Houghton M. Hepatitis delta (delta) cDNA clones: undetectable hybridization to nucleic acids from infectious non-A, non-B hepatitis materials and hepatitis B DNA. Journal of Medical Virology. 21: 239-47. PMID 3104533 DOI: 10.1002/Jmv.1890210307 |
0.464 |
|
| 1987 |
Wang K, Choo Q, Weiner AJ, Ou J, Najarian RC, Thayer RM, Mullenbach GT, Denniston KJ, Gerin JL, Houghton M. Structure, sequence and expression of the hepatitis delta (δ) viral genome Nature. 328: 456-456. DOI: 10.1038/328456A0 |
0.334 |
|
| 1986 |
Wang KS, Choo QL, Weiner AJ, Ou JH, Najarian RC, Thayer RM, Mullenbach GT, Denniston KJ, Gerin JL, Houghton M. Structure, sequence and expression of the hepatitis delta (δ) viral genome Nature. 323: 508-514. PMID 3762705 DOI: 10.1038/323508A0 |
0.431 |
|
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