Richard cosstick - Publications

Affiliations: 
Chemistry University of Liverpool, Liverpool, England, United Kingdom 

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Alexander KJ, McConville M, Williams KR, Luzyanin KV, O'Neil IA, Cosstick R. Chemistry of the 8-nitroguanine DNA lesion- reactivity, labelling and repair. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29314291 DOI: 10.1002/Chem.201705541  0.36
2016 Barbosa TM, Rittner R, Alexander K, Cosstick R, Abraham RJ. Tautomerism in 8-Nitroguanosine Studied by NMR and Theoretical Calculations. Nucleosides, Nucleotides & Nucleic Acids. 1-11. PMID 26810486 DOI: 10.1080/15257770.2015.1114127  0.718
2015 Olorunniji FJ, McPherson AL, Pavlou HJ, McIlwraith MJ, Brazier JA, Cosstick R, Stark WM. Nicked-site substrates for a serine recombinase reveal enzyme-DNA communications and an essential tethering role of covalent enzyme-DNA linkages. Nucleic Acids Research. 43: 6134-43. PMID 25990737 DOI: 10.1093/Nar/Gkv521  0.329
2015 Shah S, Sanchez J, Stewart A, Piperakis MM, Cosstick R, Nichols C, Park CK, Ma X, Wysocki V, Bitinaite J, Horton NC. Probing the run-on oligomer of activated SgrAI bound to DNA. Plos One. 10: e0124783. PMID 25880668 DOI: 10.1371/Journal.Pone.0124783  0.348
2015 Evans K, Bhamra I, Wheelhouse RT, Arnold JR, Cosstick R, Fisher J. Stabilization of a Bimolecular Triplex by 3'-S-Phosphorothiolate Modifications: An NMR and UV Thermal Melting Investigation. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 7278-84. PMID 25802084 DOI: 10.1002/Chem.201500369  0.39
2013 La Pensée L, Sabbani S, Sharma R, Bhamra I, Shore E, Chadwick AE, Berry NG, Firman J, Araujo NC, Cabral L, Cristiano ML, Bateman C, Janneh O, Gavrila A, Wu YH, ... ... Cosstick R, et al. Artemisinin-polypyrrole conjugates: synthesis, DNA binding studies and preliminary antiproliferative evaluation. Chemmedchem. 8: 709-18. PMID 23495190 DOI: 10.1002/Cmdc.201200536  0.315
2013 Piperakis MM, Gaynor JW, Fisher J, Cosstick R. Thermal stabilisation of RNA·RNA duplexes and G-quadruplexes by phosphorothiolate linkages. Organic & Biomolecular Chemistry. 11: 966-74. PMID 23250349 DOI: 10.1039/C2Ob26940F  0.32
2013 La Pensée L, Sabbani S, Sharma R, Bhamra I, Shore E, Chadwick AE, Berry NG, Firman J, Araujo NC, Cabral L, Cristiano MLS, Bateman C, Janneh O, Gavrila A, Wu YH, ... ... Cosstick R, et al. Inside Cover: Artemisinin-Polypyrrole Conjugates: Synthesis, DNA Binding Studies and Preliminary Antiproliferative Evaluation (ChemMedChem 5/2013) Chemmedchem. 8: 674-674. DOI: 10.1002/Cmdc.201390016  0.347
2013 Cosstick R. Chemical Synthesis of Nucleoside Analogues. Edited by Pedro Merino. Chembiochem. 14: 2520-2520. DOI: 10.1002/Cbic.201300703  0.378
2012 Bhamra I, Compagnone-Post P, O'Neil IA, Iwanejko LA, Bates AD, Cosstick R. Base-pairing preferences, physicochemical properties and mutational behaviour of the DNA lesion 8-nitroguanine. Nucleic Acids Research. 40: 11126-38. PMID 22965127 DOI: 10.1093/Nar/Gks799  0.387
2011 Gaynor JW, Cosstick R. Dinucleotides containing 3'-S-phosphorothiolate linkages. Methods in Molecular Biology (Clifton, N.J.). 764: 17-30. PMID 21748631 DOI: 10.1007/978-1-61779-188-8_2  0.385
2010 Gaynor JW, Piperakis MM, Fisher J, Cosstick R. Reverse-direction (5'-->3') synthesis of oligonucleotides containing a 3'-S-phosphorothiolate linkage and 3'-terminal 3'-thionucleosides. Organic & Biomolecular Chemistry. 8: 1463-70. PMID 20204222 DOI: 10.1039/B923545K  0.389
2010 Sasnauskas G, Zakrys L, Zaremba M, Cosstick R, Gaynor JW, Halford SE, Siksnys V. A novel mechanism for the scission of double-stranded DNA: BfiI cuts both 3′-5′ and 5'-3' strands by rotating a single active site Nucleic Acids Research. 38: 2399-2410. PMID 20047964 DOI: 10.1093/Nar/Gkp1194  0.354
2008 Fenna CP, Wilkinson VJ, Arnold JR, Cosstick R, Fisher J. The effect of 2'-fluorine substitutions on DNA i-motif conformation and stability. Chemical Communications (Cambridge, England). 3567-9. PMID 18654715 DOI: 10.1039/B804833A  0.34
2007 Gaynor JW, Bentley J, Cosstick R. Synthesis of the 3'-thio-nucleosides and subsequent automated synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate linkage. Nature Protocols. 2: 3122-35. PMID 18079712 DOI: 10.1038/Nprot.2007.451  0.426
2007 Gaynor JW, Brazier J, Cosstick R. Synthesis of 3′- S-Phosphorothiolate Oligonucleotides for their Potential Use in RNA Interference Nucleosides, Nucleotides & Nucleic Acids. 26: 709-712. PMID 18066885 DOI: 10.1080/15257770701490753  0.344
2007 Threlfall R, Davies A, Howarth N, Cosstick R. Foldamers derived from nucleoside beta-amino acids: PNA Or DNA? Can we have both in one place? Nucleosides, Nucleotides & Nucleic Acids. 26: 611-4. PMID 18066865 DOI: 10.1080/15257770701490399  0.344
2007 Cosstick R, Buckingham J, Brazier J, Fisher J. Stabilization of multi-stranded nucleic acid structures using 3′-S-phosphorothiolate linkages Nucleosides, Nucleotides and Nucleic Acids. 26: 555-558. PMID 18066854 DOI: 10.1080/15257770701490001  0.367
2007 Bentley J, Brazier JA, Fisher J, Cosstick R. Duplex stability of DNA.DNA and DNA.RNA duplexes containing 3'-S-phosphorothiolate linkages. Organic & Biomolecular Chemistry. 5: 3698-702. PMID 17972000 DOI: 10.1039/B713292A  0.371
2007 Jayakumar HK, Buckingham JL, Brazier JA, Berry NG, Cosstick R, Fisher J. NMR studies of the conformational effect of single and double 3'-S-phosphorothiolate substitutions within deoxythymidine trinucleotides. Magnetic Resonance in Chemistry : Mrc. 45: 340-5. PMID 17351978 DOI: 10.1002/Mrc.1977  0.352
2007 Kanaras AG, Wang Z, Brust M, Cosstick R, Bates AD. Enzymatic disassembly of DNA-gold nanostructures. Small (Weinheim An Der Bergstrasse, Germany). 3: 590-4. PMID 17315237 DOI: 10.1002/Smll.200600494  0.339
2007 Buckingham J, Brazier JA, Fisher J, Cosstick R. Incorporation of a S-glycosidic linkage into a glyconucleoside changes the conformational preference of both furanose sugars. Carbohydrate Research. 342: 16-22. PMID 17145047 DOI: 10.1016/J.Carres.2006.11.007  0.348
2007 Brennan L, Cosstick R, O'Neil IA, Van Aerschot A. Syntheses of 2′-C-amidoalkyl and 2′-C-cyanoalkyl containing oligodeoxyribonucleotides and assessment of their hybridisation affinity for complementary DNA and RNA Tetrahedron. 63: 577-585. DOI: 10.1016/J.Tet.2006.11.024  0.388
2005 Brazier JA, Fisher J, Cosstick R. Stabilization of the DNA I-motif structure by incorporation of 3'-S-phosphorothiolate linkages. Angewandte Chemie (International Ed. in English). 45: 114-7. PMID 16299827 DOI: 10.1002/Anie.200503110  0.351
2005 Proupin-Perez M, Cosstick R, Liz-Marzan LM, Salgueiriño-Maceira V, Brust M. Studies on the attachment of DNA to silica-coated nanoparticles through a Diels-Alder reaction. Nucleosides, Nucleotides & Nucleic Acids. 24: 1075-9. PMID 16248095 DOI: 10.1081/Ncn-200059170  0.308
2005 Buckingham J, Sabbagh G, Brazier J, Fisher J, Cosstick R. Control of DNA conformation using 3'-S-phosphorothiolate-modified linkages. Nucleosides, Nucleotides & Nucleic Acids. 24: 491-495. PMID 16247977 DOI: 10.1081/Ncn-200061776  0.384
2005 Elliott SL, Brazier J, Cosstick R, Connolly BA. Mechanism of the Escherichia coli DNA T:G-mismatch endonuclease (Vsr protein) probed with thiophosphate-containing oligodeoxynucleotides. Journal of Molecular Biology. 353: 692-703. PMID 16188275 DOI: 10.1016/J.Jmb.2005.08.048  0.328
2005 Hughes J, Tregova A, Tomsett AB, Jones MG, Cosstick R, Collin HA. Synthesis of the flavour precursor, alliin, in garlic tissue cultures. Phytochemistry. 66: 187-94. PMID 15652575 DOI: 10.1016/J.Phytochem.2004.11.009  0.326
2004 Pavey JB, Lawrence AJ, O'Neil IA, Vortler S, Cosstick R. Synthesis and transcription studies on 5'-triphosphates derived from 2'-C-branched-uridines: 2'-homouridine-5'-triphosphate is a substrate for T7 RNA polymerase. Organic & Biomolecular Chemistry. 2: 869-75. PMID 15007416 DOI: 10.1039/B314348A  0.337
2004 Sabbagh G, Fettes KJ, Gosain R, O'Neil IA, Cosstick R. Synthesis of phosphorothioamidites derived from 3'-thio-3'-deoxythymidine and 3'-thio-2',3'-dideoxycytidine and the automated synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate linkage. Nucleic Acids Research. 32: 495-501. PMID 14742664 DOI: 10.1093/Nar/Gkh189  0.399
2004 Beevers AP, Fettes KJ, Sabbagh G, Murad FK, Arnold JR, Cosstick R, Fisher J. NMR and UV studies of 3'-S-phosphorothiolate modified DNA in a DNA : RNA hybrid dodecamer duplex; implications for antisense drug design. Organic & Biomolecular Chemistry. 2: 114-9. PMID 14737669 DOI: 10.1039/B311923H  0.411
2003 Fehring V, Knights S, Chan MY, O'Neil IA, Cosstick R. Studies on 2'-alpha-C-carboxyalkyl nucleosides and their application to a stereocontrolled nucleobase exchange process. Organic & Biomolecular Chemistry. 1: 123-8. PMID 12929398 DOI: 10.1039/B208786N  0.364
2003 Kanaras AG, Wang Z, Bates AD, Cosstick R, Brust M. Towards multistep nanostructure synthesis: programmed enzymatic self-assembly of DNA/gold systems. Angewandte Chemie (International Ed. in English). 42: 191-4. PMID 12532347 DOI: 10.1002/Anie.200390075  0.367
2002 Beevers AP, Fettes KJ, O'Neil IA, Roberts SM, Arnold JR, Cosstick R, Fisher J. Probing the effect of a 3'-S-phosphorothiolate link on the conformation of a DNA:RNA hybrid; implications for antisense drug design. Chemical Communications (Cambridge, England). 1458-9. PMID 12189842 DOI: 10.1039/B203582K  0.39
2002 Calcerrada-Muñoz N, O'Neil I, Cosstick R. Novel macrocycles derived from nucleosides. Nucleosides, Nucleotides & Nucleic Acids. 20: 1347-50. PMID 11563019 DOI: 10.1081/Ncn-100002552  0.338
2001 Fettes KJ, O'Neil I, Roberts SM, Cosstick R. Solid-phase synthesis of oligodeoxynucleotides containing 3'-S-phosphorothiolate linkages. Nucleosides, Nucleotides & Nucleic Acids. 20: 1351-4. PMID 11563020 DOI: 10.1081/Ncn-100002553  0.393
2001 Brennan L, Fettes KJ, O'Neil IA, Cosstick R. The synthesis of, and studies on, 2'-C-modified nucleotides. Nucleosides, Nucleotides & Nucleic Acids. 20: 1339-1341. PMID 11563017 DOI: 10.1081/Ncn-100002550  0.378
2000 Fehring V, Chan MY, O’Neil IA, Cosstick R. A novel stereo-controlled nucleobase exchange process for the synthesis of 2′-C-branched nucleosides Journal of the Chemical Society-Perkin Transactions 1. 3185-3187. DOI: 10.1039/B007099H  0.34
2000 Elzagheid M, Mattila K, Oivanen M, Jones B, Cosstick R, Lönnberg H. Hydrolytic Reactions of thecis-Methyl Ester of 3′-Deoxy-3′-thiothymidine 3′,5′-Cyclic(phosphorothiolate) European Journal of Organic Chemistry. 2000: 1987-1991. DOI: 10.1002/(Sici)1099-0690(200005)2000:10<1987::Aid-Ejoc1987>3.0.Co;2-X  0.378
1999 Elzagheid MI, Oivanen M, Klika KD, Jones BCNM, Cosstick R, Lönnberg H. Hydrolytic Reactions of 3′-Deoxy-3′-thioinosylyl-(3′→ >5′)-uridine; An RNA Dinucleotide Containing a 3′-S-Phosphorothiolate Linkage Nucleosides and Nucleotides. 18: 2093-2108. DOI: 10.1080/07328319908044866  0.401
1999 Elzagheid M, Oivanen M, Colin B, Jones NM, Cosstick R, Lönnberg H. Hydrolytic Reactions of an RNA Dinucleotide Containing a 3′-S-Phosphorothiolate Linkage Nucleosides and Nucleotides. 18: 1265-1266. DOI: 10.1080/07328319908044687  0.338
1999 Chan M, Fairhurst RA, Collingwood SP, Fisher J, Arnold JRP, Cosstick R, O’Neil IA. Synthesis and duplex stability of oligodeoxyribonucleotides containing a 2′→5′-amide linkage Journal of the Chemical Society-Perkin Transactions 1. 315-320. DOI: 10.1039/A808505F  0.449
1998 Pavey JBJ, Cosstick R, O'Neil IA. The synthesis of a novel 2′,3′-cyclic phosphate derived from 2′-homouridine Tetrahedron Letters. 39: 8923-8924. DOI: 10.1016/S0040-4039(98)01952-2  0.386
1998 Pavey JB, Lawrence AJ, Potter AJ, Cosstick R, O'Neil IA. The synthesis of 2′-homouridine, its incorporation into a dinucleoside monophosphate and hydrolytic behaviour of the dimer Tetrahedron Letters. 39: 6967-6970. DOI: 10.1016/S0040-4039(98)01478-6  0.412
1997 Shah R, Cosstick R, West SC. The RuvC protein dimer resolves Holliday junctions by a dual incision mechanism that involves base-specific contacts. The Embo Journal. 16: 1464-72. PMID 9135161 DOI: 10.1093/Emboj/16.6.1464  0.356
1997 Witch EM, Cosstick R. Dinucleoside Monophosphate Analogues Containing Disulfide Linkages Tetrahedron Letters. 38: 6745-6748. DOI: 10.1080/07328319708006228  0.336
1997 Lawrence AJ, Pavey JBJ, O'Neil IA, Cosstick R. The Synthesis of 2′-C-Functionalised Nucleosides for Incorporation into Catalytic RNA Nucleosides and Nucleotides. 16: 1497-1501. DOI: 10.1080/07328319708006215  0.358
1997 Lawrence AJ, Pavey JBJ, Chan M, Fairhurst RA, Collingwood SP, Fisher J, Cosstick R, O’Neil IA. Synthesis, structure and reactions of uridine2′-C,3′-O-γ-butyrolactone:versatile intermediate for the synthesis of 2′-C-branchednucleosides Journal of the Chemical Society-Perkin Transactions 1. 2761-2768. DOI: 10.1039/A702088K  0.414
1996 Weinstein LB, Earnshaw DJ, Cosstick R, Cech TR. Synthesis and characterization of an RNA dinucleotide containing a 3'-S-phosphorothiolate linkage Journal of the American Chemical Society. 118: 10341-10350. DOI: 10.1021/Ja9616903  0.398
1996 Higson AP, Scott GK, Earnshaw DJ, Baxter AD, Taylor RA, Cosstick R. Synthesis and structure of S-nucleosidyl S-aryl disulfides and their reaction with phosphites Tetrahedron. 52: 1027-1034. DOI: 10.1016/0040-4020(95)00936-1  0.381
1995 Lawrence AJ, Pavey JB, O'Neil IA, Cosstick R. Sunthesis of functionalised 2′-C-branched nucleosides via their γ-butyrolactones Tetrahedron Letters. 36: 6341-6344. DOI: 10.1016/0040-4039(95)01226-8  0.388
1994 Li X, Scott GK, Baxter AD, Taylor RJ, Vyle JS, Cosstick R. Application of the Michaelis–Arbusov reaction to the synthesis of internucleoside 3′-S-phosphorothiolate inkages Journal of the Chemical Society-Perkin Transactions 1. 2123-2129. DOI: 10.1039/P19940002123  0.687
1993 Cruse WBT, Salisbury SA, Brown T, Cosstick R, Eckstein F, Kennard O. Chiral phosphorothioate analogues of B-DNA: The crystal structure of Rp-d¦Gp(S)CpGp(S)CpGp(S)C¦☆ Journal of Molecular Biology. 192: 891-905. DOI: 10.2210/Pdb1D97/Pdb  0.343
1993 Li X, Cosstick R. Application of an intramolecular Michaelis-Arbusov reaction to the synthesis of nucleoside 3'-S,5'-O-cyclic phosphorothiolate triesters Journal of the Chemical Society-Perkin Transactions 1. 1091-1092. DOI: 10.1039/P19930001091  0.419
1993 Milton J, Connolly BA, Nikiforovc TT, Cosstick R. Site-specific disulfide bridges in oligodeoxyribonucleotide duplexes containing 6-mercaptopurine and 4-thiothymine bases Journal of the Chemical Society, Chemical Communications. 779-780. DOI: 10.1039/C39930000779  0.342
1992 Vyle JS, Connolly BA, Kemp D, Cosstick R. Sequence- and strand-specific cleavage in oligodeoxyribonucleotides and DNA containing 3′-thiothymidine Biochemistry®. 31: 3012-3018. PMID 1550825 DOI: 10.1021/Bi00126A024  0.694
1992 Vyle JS, Li X, Cosstick R. New methods for the synthesis of 3′-S-phosphorothiolate internucleoside linkages Tetrahedron Letters. 33: 3017-3020. DOI: 10.1016/S0040-4039(00)79587-6  0.669
1992 Li X, Andrews DM, Cosstick R. Synthesis of a dinucleoside 3′-S-phosphorothiolate containing 2′-deoxy-3′-thioadenosine Tetrahedron. 48: 2729-2738. DOI: 10.1016/S0040-4020(01)88532-X  0.469
1991 Cosstick R, Douglas ME. A novel approach to sequence-specific cross-linking in oligonucleotides. Nucleosides, Nucleotides & Nucleic Acids. 10: 633-634. DOI: 10.1080/07328319108046555  0.31
1991 Cosstick R, Douglas ME. Synthesis of a dinucleoside monophosphate analogue containing 6-N-(2-aminoethyl)-2'-deoxyadenosine. A novel approach to sequence specific cross-linking in synthetic oligonucleotides Journal of the Chemical Society-Perkin Transactions 1. 1035-1040. DOI: 10.1039/P19910001035  0.372
1990 Cosstick R, Vyle JS. Synthesis and properties of dithymidine phosphate analogues containing 3'-thiothymidine. Nucleic Acids Research. 18: 829-35. PMID 2315041 DOI: 10.1093/Nar/18.4.829  0.672
1990 Newman PC, Williams DM, Cosstick R, Seela F, Connolly BA. Interaction of the EcoRV restriction endonuclease with the deoxyadenosine and thymidine bases in its recognition hexamer d(GATATC) Biochemistry. 29: 9902-9910. PMID 2271628 DOI: 10.1021/Bi00494A021  0.316
1990 Newman PC, Nwosu VU, Williams DM, Cosstick R, Seela F, Connolly BA. Incorporation of a complete set of deoxyadenosine and thymidine analogues suitable for the study of protein nucleic acid interactions into oligodeoxynucleotides. Application to the EcoRV restriction endonuclease and modification methylase. Biochemistry. 29: 9891-901. PMID 2271627 DOI: 10.1021/Bi00494A020  0.337
1990 Agathocleous DC, Bulman Page PC, Cosstick R, Galpin IJ, McLennan AG, Prescott M. Synthesis of bridged dinucleosides Tetrahedron. 46: 2047-2058. DOI: 10.1016/S0040-4020(01)89771-4  0.356
1989 Cosstick R, Vyle JS. Solid phase synthesis of oligonucleotides containing 3′-thiothymidine Tetrahedron Letters. 30: 4693-4696. DOI: 10.1016/S0040-4039(01)80776-0  0.682
1988 Cosstick R, Williams DM. An approach to the stereoselective synthesis of Sp-dinucleoside phosphorothioates using phosphotriester chemistry. Nucleic Acids Research. 15: 9921-32. PMID 3480505 DOI: 10.1093/Nar/15.23.9921  0.372
1988 Cosstick R, Vyle JS. Synthesis and phosphorus–sulphur bond cleavage of 3′-thiothymidylyl(3′-5′)thymidine Journal of the Chemical Society, Chemical Communications. 992-993. DOI: 10.1039/C39880000992  0.688
1987 Cruse WB, Salisbury SA, Brown T, Cosstick R, Eckstein F, Kennard O. Chiral phosphorothioate analogues of B-DNA. The crystal structure of Rp-d[Gp(S)CpGp(S)CpGp(S)C]. Journal of Molecular Biology. 192: 891-905. PMID 3108513 DOI: 10.1016/0022-2836(86)90035-5  0.361
1987 Cosstick R, Eckstein F, Kennard O, Cruse WBT, Salisbury SA. Phosphorothioate Analogues : Probes for Studying DNA Conformation Phosphorus and Sulfur and the Related Elements. 30: 555-558. DOI: 10.1080/03086648708079125  0.34
1986 Taylor JW, Schmidt W, Cosstick R, Okruszek A, Eckstein F. The use of phosphorothioate-modified DNA in restriction enzyme reactions to prepare nicked DNA. Nucleic Acids Research. 13: 8749-64. PMID 3001649 DOI: 10.1093/Nar/13.24.8749  0.365
1985 Cosstick R, Eckstein F. Synthesis of d(GC) and d(CG) octamers containing alternating phosphorothioate linkages: effect of the phosphorothioate group on the B-Z transition. Biochemistry. 24: 3630-8. PMID 4041432 DOI: 10.1021/Bi00335A035  0.309
1984 Cosstick R, McLaughlin LW, Eckstein F. Fluorescent labelling of tRNA and oligodeoxynucleotides using T4 RNA ligase. Nucleic Acids Research. 12: 1791-810. PMID 6366740 DOI: 10.1093/Nar/12.4.1791  0.376
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