Year |
Citation |
Score |
2023 |
Grohs L, Cheng L, Cönen S, Haddad BG, Bülow A, Toklucu I, Ernst L, Körner J, Schmalzing G, Lampert A, Machtens JP, Hausmann R. Diclofenac and other non-steroidal anti-inflammatory drugs (NSAIDs) are competitive antagonists of the human P2X3 receptor. Frontiers in Pharmacology. 14: 1120360. PMID 37007008 DOI: 10.3389/fphar.2023.1120360 |
0.322 |
|
2022 |
Schmalzing G, Markwardt F. Established Protocols for cRNA Expression and Voltage-Clamp Characterization of the P2X7 Receptor in Xenopus laevis Oocytes. Methods in Molecular Biology (Clifton, N.J.). 2510: 157-192. PMID 35776325 DOI: 10.1007/978-1-0716-2384-8_9 |
0.384 |
|
2022 |
Schiller IC, Jacobson KA, Wen Z, Malisetty A, Schmalzing G, Markwardt F. Dihydropyridines Potentiate ATP-Induced Currents Mediated by the Full-Length Human P2X5 Receptor. Molecules (Basel, Switzerland). 27. PMID 35335209 DOI: 10.3390/molecules27061846 |
0.384 |
|
2020 |
Trang M, Schmalzing G, Müller CE, Markwardt F. Dissection of P2X4 and P2X7 Receptor Current Components in BV-2 Microglia. International Journal of Molecular Sciences. 21. PMID 33187309 DOI: 10.3390/ijms21228489 |
0.38 |
|
2020 |
Illes P, Müller CE, Jacobson KA, Grutter T, Nicke A, Fountain SJ, Kennedy C, Schmalzing G, Jarvis MF, Stojilkovic SS, King BF, Di Virgilio F. Update of P2X receptor properties and their pharmacology: IUPHAR Review 30. British Journal of Pharmacology. PMID 33125712 DOI: 10.1111/bph.15299 |
0.4 |
|
2020 |
Rühlmann AH, Körner J, Hausmann R, Bebrivenski N, Neuhof C, Detro-Dassen S, Hautvast P, Benasolo CA, Meents J, Machtens JP, Schmalzing G, Lampert A. Uncoupling sodium channel dimers rescues the phenotype of a pain-linked Nav1.7 mutation. British Journal of Pharmacology. PMID 32663327 DOI: 10.1111/Bph.15196 |
0.309 |
|
2019 |
Obrecht AS, Urban N, Schaefer M, Röse A, Kless A, Meents JE, Lampert A, Abdelrahman A, Müller CE, Schmalzing G, Hausmann R. Identification of aurintricarboxylic acid as a potent allosteric antagonist of P2X1 and P2X3 receptors. Neuropharmacology. 107749. PMID 31461640 DOI: 10.1016/J.Neuropharm.2019.107749 |
0.466 |
|
2018 |
Stephan G, Huang L, Tang Y, Vilotti S, Fabbretti E, Yu Y, Nörenberg W, Franke H, Gölöncsér F, Sperlágh B, Dopychai A, Hausmann R, Schmalzing G, Rubini P, Illes P. Author Correction: The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel. Nature Communications. 9: 3351. PMID 30120221 DOI: 10.1038/S41467-018-05621-7 |
0.345 |
|
2018 |
Kaluza L, Meents JE, Hampl M, Rösseler C, Hautvast PAI, Detro-Dassen S, Hausmann R, Schmalzing G, Lampert A. Loss-of-function of Nav1.8/D1639N linked to human pain can be rescued by lidocaine. Pflugers Archiv : European Journal of Physiology. PMID 30099632 DOI: 10.1007/S00424-018-2189-X |
0.346 |
|
2018 |
Hiller SD, Heldmann S, Richter K, Jurastow I, Küllmar M, Hecker A, Wilker S, Fuchs-Moll G, Manzini I, Schmalzing G, Kummer W, Padberg W, McIntosh JM, Damm J, Zakrzewicz A, et al. β-Nicotinamide Adenine Dinucleotide (β-NAD) Inhibits ATP-Dependent IL-1β Release from Human Monocytic Cells. International Journal of Molecular Sciences. 19. PMID 29642561 DOI: 10.3390/Ijms19041126 |
0.317 |
|
2018 |
Stephan G, Huang L, Tang Y, Vilotti S, Fabbretti E, Yu Y, Nörenberg W, Franke H, Göröncsér F, Sperlágh B, Dopychai A, Hausmann R, Schmalzing G, Rubini P, Illes P. The ASIC3/P2X3 cognate receptor is a pain-relevant and ligand-gated cationic channel. Nature Communications. 9: 1354. PMID 29636447 DOI: 10.1038/S41467-018-03728-5 |
0.515 |
|
2018 |
Di Virgilio F, Schmalzing G, Markwardt F. The Elusive P2X7 Macropore. Trends in Cell Biology. PMID 29439897 DOI: 10.1016/J.Tcb.2018.01.005 |
0.431 |
|
2018 |
Hein A, Kless A, Hausmann R, Markwardt F, Schmalzing G. Role of the Left Flipper Domain in the Homotrimeric Assembly and Function of P2X Receptors Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.721 |
0.417 |
|
2018 |
Dopychai A, Heidenreich S, Pokam CF, Schmalzing G. Identification of Hyperekplexia Mutations that Impair the Homopentameric Assembly of the Glycine Receptor GLYRA1 Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.1754 |
0.377 |
|
2017 |
Schneider M, Prudic K, Pippel A, Klapperstück M, Braam U, Müller CE, Schmalzing G, Markwardt F. Interaction of Purinergic P2X4 and P2X7 Receptor Subunits. Frontiers in Pharmacology. 8: 860. PMID 29213241 DOI: 10.3389/Fphar.2017.00860 |
0.526 |
|
2017 |
Pippel A, Stolz M, Woltersdorf R, Kless A, Schmalzing G, Markwardt F. Localization of the gate and selectivity filter of the full-length P2X7 receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 28235784 DOI: 10.1073/Pnas.1610414114 |
0.448 |
|
2017 |
Dopychai A, Hausmann R, Krüger L, Gründer S, Schmalzing G. Blue Native Page Evidence that Plasma Membrane-Bound Human ENaC Channels Share a Trimeric Architecture with Full-Length Human ASIC1 and ASIC2 Biophysical Journal. 112: 4-7. DOI: 10.1016/J.Bpj.2016.11.2584 |
0.341 |
|
2016 |
Xie J, Liu S, Wu B, Li G, Rao S, Zou L, Yi Z, Zhang C, Jia T, Zhao S, Schmalzing G, Hausmann R, Nie H, Li G, Liang S. The protective effect of resveratrol in the transmission of neuropathic pain mediated by the P2X7 receptor in the dorsal root ganglia. Neurochemistry International. PMID 28027922 DOI: 10.1016/J.Neuint.2016.12.006 |
0.323 |
|
2016 |
Stephan G, Kowalski-Jahn M, Zens C, Schmalzing G, Illes P, Hausmann R. Inter-subunit disulfide locking of the human P2X3 receptor elucidates ectodomain movements associated with channel gating. Purinergic Signalling. 12: 221-33. PMID 26825305 DOI: 10.1007/S11302-016-9496-5 |
0.42 |
|
2016 |
Schmalzing G, Detro-Dassen S, Fahlke C, Markwardt F. Oligomerization States of LRRC8A and LRRC8B, Essential Components of the Volume-Regulated Anion Channel VRAC Biophysical Journal. 110: 119a-120a. DOI: 10.1016/J.Bpj.2015.11.695 |
0.369 |
|
2015 |
Ronstedt K, Sternberg D, Detro-Dassen S, Gramkow T, Begemann B, Becher T, Kilian P, Grieschat M, Machtens JP, Schmalzing G, Fischer M, Fahlke C. Impaired surface membrane insertion of homo- and heterodimeric human muscle chloride channels carrying amino-terminal myotonia-causing mutations. Scientific Reports. 5: 15382. PMID 26502825 DOI: 10.1038/Srep15382 |
0.368 |
|
2015 |
Kowalski M, Hausmann R, Schmid J, Dopychai A, Stephan G, Tang Y, Schmalzing G, Illes P, Rubini P. Flexible subunit stoichiometry of functional human P2X2/3 heteromeric receptors. Neuropharmacology. PMID 26184350 DOI: 10.1016/J.Neuropharm.2015.07.008 |
0.51 |
|
2015 |
Stolz M, Klapperstück M, Kendzierski T, Detro-Dassen S, Panning A, Schmalzing G, Markwardt F. Homodimeric anoctamin-1, but not homodimeric anoctamin-6, is activated by calcium increases mediated by the P2Y1 and P2X7 receptors. PflüGers Archiv : European Journal of Physiology. 467: 2121-40. PMID 25592660 DOI: 10.1007/S00424-015-1687-3 |
0.426 |
|
2015 |
Hausmann R, Kless A, Schmalzing G. Key sites for P2X receptor function and multimerization: overview of mutagenesis studies on a structural basis. Current Medicinal Chemistry. 22: 799-818. PMID 25439586 DOI: 10.2174/0929867322666141128163215 |
0.488 |
|
2015 |
Dopychai A, Pokam CF, Schmalzing G. Aromatic Residues in the Transmembrane Helices Play an Essential Role in the Homopentameric Assembly of the Glucl α Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.2356 |
0.485 |
|
2014 |
Kowalski M, Hausmann R, Dopychai A, Grohmann M, Franke H, Nieber K, Schmalzing G, Illes P, Riedel T. Conformational flexibility of the agonist binding jaw of the human P2X3 receptor is a prerequisite for channel opening. British Journal of Pharmacology. 171: 5093-112. PMID 24989924 DOI: 10.1111/Bph.12830 |
0.472 |
|
2014 |
Hausmann R, Bahrenberg G, Kuhlmann D, Schumacher M, Braam U, Bieler D, Schlusche I, Schmalzing G. A hydrophobic residue in position 15 of the rP2X3 receptor slows desensitization and reveals properties beneficial for pharmacological analysis and high-throughput screening. Neuropharmacology. 79: 603-15. PMID 24452010 DOI: 10.1016/J.Neuropharm.2014.01.010 |
0.491 |
|
2014 |
Markwardt F, Pippel A, Stolz M, Rahn T, Schmalzing G. Function of the second Transmembrane Domain of the Human P2X7 Receptor Biophysical Journal. 106: 154. DOI: 10.1016/J.Bpj.2013.11.882 |
0.493 |
|
2014 |
Schmalzing G, Detro-Dassen S, Markwardt F. Probing the Transmembrane Topology of TMEM16A(A)/Anoctamin-1 by Cysteine Scanning Mutagenesis Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.836 |
0.342 |
|
2013 |
Sebastian K, Detro-Dassen S, Rinis N, Fahrenkamp D, Müller-Newen G, Merk HF, Schmalzing G, Zwadlo-Klarwasser G, Baron JM. Characterization of SLCO5A1/OATP5A1, a solute carrier transport protein with non-classical function. Plos One. 8: e83257. PMID 24376674 DOI: 10.1371/Journal.Pone.0083257 |
0.333 |
|
2013 |
Hausmann R, Günther J, Kless A, Kuhlmann D, Kassack MU, Bahrenberg G, Markwardt F, Schmalzing G. Salt bridge switching from Arg290/Glu167 to Arg290/ATP promotes the closed-to-open transition of the P2X2 receptor. Molecular Pharmacology. 83: 73-84. PMID 23041661 DOI: 10.1124/Mol.112.081489 |
0.488 |
|
2013 |
Schmalzing G, Detro-Dassen S, Braam U, Klapperstueck M, Markwardt F. Disulfide Bond Connectivity and Oligomeric State of Anoctamin-1 Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.403 |
0.358 |
|
2013 |
Markwardt F, Woltersdorf R, Klapperstück M, Schmalzing G. Co-Expressed Pannexin-1 and the P2X7 Receptor do not Interact Functionally or Physically at the Plasma Membrane of Xenopus Laevis Oocytes Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.3452 |
0.502 |
|
2012 |
Hausmann R, Schmalzing G. P2X1 and P2X2 receptors in the central nervous system as possible drug targets. Cns & Neurological Disorders Drug Targets. 11: 675-86. PMID 22963438 DOI: 10.2174/187152712803581128 |
0.455 |
|
2012 |
Nörenberg W, Sobottka H, Hempel C, Plötz T, Fischer W, Schmalzing G, Schaefer M. Positive allosteric modulation by ivermectin of human but not murine P2X7 receptors. British Journal of Pharmacology. 167: 48-66. PMID 22506590 DOI: 10.1111/J.1476-5381.2012.01987.X |
0.4 |
|
2012 |
Hausmann R, Bodnar M, Woltersdorf R, Wang H, Fuchs M, Messemer N, Qin Y, Günther J, Riedel T, Grohmann M, Nieber K, Schmalzing G, Rubini P, Illes P. ATP binding site mutagenesis reveals different subunit stoichiometry of functional P2X2/3 and P2X2/6 receptors. The Journal of Biological Chemistry. 287: 13930-43. PMID 22378790 DOI: 10.1074/Jbc.M112.345207 |
0.527 |
|
2012 |
El-Wahsch D, Hausmann R, Schumacher M, Braam U, Detro-Dassen S, Schmalzing G. Disulfide-Driven Assembly and Aggregation of the P2X Receptor Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.347 |
0.507 |
|
2011 |
Kubick C, Schmalzing G, Markwardt F. The effect of anions on the human P2X7 receptor. Biochimica Et Biophysica Acta. 1808: 2913-22. PMID 21872569 DOI: 10.1016/J.Bpj.2011.11.1848 |
0.444 |
|
2011 |
Moraga-Cid G, Yevenes GE, Schmalzing G, Peoples RW, Aguayo LG. A Single phenylalanine residue in the main intracellular loop of α1 γ-aminobutyric acid type A and glycine receptors influences their sensitivity to propofol. Anesthesiology. 115: 464-73. PMID 21673564 DOI: 10.1097/Aln.0B013E31822550F7 |
0.438 |
|
2011 |
Pult F, Fallah G, Braam U, Detro-Dassen S, Niculescu C, Laube B, Schmalzing G. Robust post-translocational N-glycosylation at the extreme C-terminus of membrane and secreted proteins in Xenopus laevis oocytes and HEK293 cells. Glycobiology. 21: 1147-60. PMID 21303814 DOI: 10.1093/Glycob/Cwr013 |
0.336 |
|
2011 |
Baqi Y, Hausmann R, Rosefort C, Rettinger J, Schmalzing G, Müller CE. Discovery of potent competitive antagonists and positive modulators of the P2X2 receptor. Journal of Medicinal Chemistry. 54: 817-30. PMID 21207957 DOI: 10.1021/Jm1012193 |
0.455 |
|
2011 |
Wolf C, Rosefort C, Fallah G, Kassack MU, Hamacher A, Bodnar M, Wang H, Illes P, Kless A, Bahrenberg G, Schmalzing G, Hausmann R. Molecular determinants of potent P2X2 antagonism identified by functional analysis, mutagenesis, and homology docking. Molecular Pharmacology. 79: 649-61. PMID 21191044 DOI: 10.1124/Mol.110.068700 |
0.452 |
|
2011 |
Bodnar M, Wang H, Riedel T, Hintze S, Kato E, Fallah G, Gröger-Arndt H, Giniatullin R, Grohmann M, Hausmann R, Schmalzing G, Illes P, Rubini P. Amino acid residues constituting the agonist binding site of the human P2X3 receptor. The Journal of Biological Chemistry. 286: 2739-49. PMID 21098022 DOI: 10.1074/Jbc.M110.167437 |
0.476 |
|
2011 |
Fallah G, Römer T, Detro-Dassen S, Braam U, Markwardt F, Schmalzing G. TMEM16A(a)/anoctamin-1 shares a homodimeric architecture with CLC chloride channels. Molecular & Cellular Proteomics : McP. 10: M110.004697. PMID 20974900 DOI: 10.1074/Mcp.M110.004697 |
0.375 |
|
2011 |
Fallah G, Detro-Dassen S, Braam U, Rudolph F, Markwardt F, Schmalzing G. Higher Order Structure of TMEM16a/Anoctamin-1 as Compared to Other Chloride-Conducting Channels Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.1671 |
0.442 |
|
2010 |
Adinolfi E, Cirillo M, Woltersdorf R, Falzoni S, Chiozzi P, Pellegatti P, Callegari MG, Sandonà D, Markwardt F, Schmalzing G, Di Virgilio F. Trophic activity of a naturally occurring truncated isoform of the P2X7 receptor. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3393-404. PMID 20453110 DOI: 10.1096/Fj.09-153601 |
0.458 |
|
2010 |
Flittiger B, Klapperstück M, Schmalzing G, Markwardt F. Effects of protons on macroscopic and single-channel currents mediated by the human P2X7 receptor. Biochimica Et Biophysica Acta. 1798: 947-57. PMID 20138022 DOI: 10.1016/J.Bbamem.2010.01.023 |
0.436 |
|
2010 |
Haeger S, Kuzmin D, Detro-Dassen S, Lang N, Kilb M, Tsetlin V, Betz H, Laube B, Schmalzing G. An intramembrane aromatic network determines pentameric assembly of Cys-loop receptors. Nature Structural & Molecular Biology. 17: 90-8. PMID 20023641 DOI: 10.1038/Nsmb.1721 |
0.414 |
|
2010 |
Meis S, Hamacher A, Hongwiset D, Marzian C, Wiese M, Eckstein N, Royer HD, Communi D, Boeynaems JM, Hausmann R, Schmalzing G, Kassack MU. NF546 [4,4'-(carbonylbis(imino-3,1-phenylene-carbonylimino-3,1-(4-methyl-phenylene)-carbonylimino))-bis(1,3-xylene-alpha,alpha'-diphosphonic acid) tetrasodium salt] is a non-nucleotide P2Y11 agonist and stimulates release of interleukin-8 from human monocyte-derived dendritic cells. The Journal of Pharmacology and Experimental Therapeutics. 332: 238-47. PMID 19815812 DOI: 10.1124/Jpet.109.157750 |
0.367 |
|
2010 |
Haeger S, Kuzmin D, Detro-Dassen S, Lang N, Kilb M, Tsetlin V, Betz H, Laube B, Schmalzing G. Aromatic Interfaces between Transmembrane Helices M1/M4 and M3/M4 Play a Key Role in Cys-loop Receptor Assembly Biophysical Journal. 98: 417a-418a. DOI: 10.1016/J.Bpj.2009.12.2256 |
0.434 |
|
2009 |
Stanchev D, Blosa M, Milius D, Gerevich Z, Rubini P, Schmalzing G, Eschrich K, Schaefer M, Wirkner K, Illes P. Cross-inhibition between native and recombinant TRPV1 and P2X(3) receptors. Pain. 143: 26-36. PMID 19223122 DOI: 10.1016/J.Pain.2009.01.006 |
0.482 |
|
2008 |
Yevenes GE, Moraga-Cid G, Peoples RW, Schmalzing G, Aguayo LG. A selective G betagamma-linked intracellular mechanism for modulation of a ligand-gated ion channel by ethanol. Proceedings of the National Academy of Sciences of the United States of America. 105: 20523-8. PMID 19074265 DOI: 10.1073/Pnas.0806257105 |
0.304 |
|
2008 |
Becker D, Woltersdorf R, Boldt W, Schmitz S, Braam U, Schmalzing G, Markwardt F. The P2X7 carboxyl tail is a regulatory module of P2X7 receptor channel activity. The Journal of Biological Chemistry. 283: 25725-34. PMID 18617511 DOI: 10.1074/Jbc.M803855200 |
0.518 |
|
2008 |
Detro-Dassen S, Schänzler M, Lauks H, Martin I, zu Berstenhorst SM, Nothmann D, Torres-Salazar D, Hidalgo P, Schmalzing G, Fahlke C. Conserved dimeric subunit stoichiometry of SLC26 multifunctional anion exchangers. The Journal of Biological Chemistry. 283: 4177-88. PMID 18073211 DOI: 10.1074/Jbc.M704924200 |
0.413 |
|
2007 |
Franklin C, Braam U, Eisele T, Schmalzing G, Hausmann R. Lack of evidence for direct phosphorylation of recombinantly expressed P2X(2) and P2X (3) receptors by protein kinase C. Purinergic Signalling. 3: 377-88. PMID 18404451 DOI: 10.1007/S11302-007-9067-X |
0.479 |
|
2007 |
Riedel T, Schmalzing G, Markwardt F. Influence of extracellular monovalent cations on pore and gating properties of P2X7 receptor-operated single-channel currents. Biophysical Journal. 93: 846-58. PMID 17483156 DOI: 10.1529/Biophysj.106.103614 |
0.482 |
|
2007 |
Riedel T, Lozinsky I, Schmalzing G, Markwardt F. Kinetics of P2X7 receptor-operated single channels currents. Biophysical Journal. 92: 2377-91. PMID 17189308 DOI: 10.1529/Biophysj.106.091413 |
0.454 |
|
2007 |
Saiyed T, Paarmann I, Schmitt B, Haeger S, Sola M, Schmalzing G, Weissenhorn W, Betz H. Molecular basis of gephyrin clustering at inhibitory synapses: role of G- and E-domain interactions. The Journal of Biological Chemistry. 282: 5625-32. PMID 17182610 DOI: 10.1074/Jbc.M610290200 |
0.382 |
|
2006 |
Yevenes GE, Moraga-Cid G, Guzmán L, Haeger S, Oliveira L, Olate J, Schmalzing G, Aguayo LG. Molecular determinants for G protein betagamma modulation of ionotropic glycine receptors. The Journal of Biological Chemistry. 281: 39300-7. PMID 17040914 DOI: 10.1074/Jbc.M608272200 |
0.478 |
|
2006 |
Duckwitz W, Hausmann R, Aschrafi A, Schmalzing G. P2X5 subunit assembly requires scaffolding by the second transmembrane domain and a conserved aspartate. The Journal of Biological Chemistry. 281: 39561-72. PMID 17001079 DOI: 10.1074/Jbc.M606113200 |
0.688 |
|
2006 |
Hausmann R, Rettinger J, Gerevich Z, Meis S, Kassack MU, Illes P, Lambrecht G, Schmalzing G. The suramin analog 4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic acid (NF110) potently blocks P2X3 receptors: subtype selectivity is determined by location of sulfonic acid groups. Molecular Pharmacology. 69: 2058-67. PMID 16551782 DOI: 10.1124/Mol.106.022665 |
0.411 |
|
2005 |
Ullmann H, Meis S, Hongwiset D, Marzian C, Wiese M, Nickel P, Communi D, Boeynaems JM, Wolf C, Hausmann R, Schmalzing G, Kassack MU. Synthesis and structure-activity relationships of suramin-derived P2Y11 receptor antagonists with nanomolar potency. Journal of Medicinal Chemistry. 48: 7040-8. PMID 16250663 DOI: 10.1021/Jm050301P |
0.408 |
|
2005 |
Rettinger J, Braun K, Hochmann H, Kassack MU, Ullmann H, Nickel P, Schmalzing G, Lambrecht G. Profiling at recombinant homomeric and heteromeric rat P2X receptors identifies the suramin analogue NF449 as a highly potent P2X1 receptor antagonist. Neuropharmacology. 48: 461-8. PMID 15721178 DOI: 10.1016/J.Neuropharm.2004.11.003 |
0.467 |
|
2004 |
Seyffert C, Schmalzing G, Markwardt F. Dissecting individual current components of co-expressed human P2X1 and P2X7 receptors. Current Topics in Medicinal Chemistry. 4: 1719-30. PMID 15579104 DOI: 10.2174/1568026043387160 |
0.496 |
|
2004 |
Nicke A, Thurau H, Sadtler S, Rettinger J, Schmalzing G. Assembly of nicotinic alpha7 subunits in Xenopus oocytes is partially blocked at the tetramer level. Febs Letters. 575: 52-8. PMID 15388332 DOI: 10.1016/J.Febslet.2004.08.035 |
0.382 |
|
2004 |
Aschrafi A, Sadtler S, Niculescu C, Rettinger J, Schmalzing G. Trimeric architecture of homomeric P2X2 and heteromeric P2X1+2 receptor subtypes. Journal of Molecular Biology. 342: 333-43. PMID 15313628 DOI: 10.1016/J.Jmb.2004.06.092 |
0.735 |
|
2004 |
Gendreau S, Voswinkel S, Torres-Salazar D, Lang N, Heidtmann H, Detro-Dassen S, Schmalzing G, Hidalgo P, Fahlke C. A trimeric quaternary structure is conserved in bacterial and human glutamate transporters. The Journal of Biological Chemistry. 279: 39505-12. PMID 15265858 DOI: 10.1074/Jbc.M408038200 |
0.307 |
|
2004 |
Rettinger J, Schmalzing G. Desensitization masks nanomolar potency of ATP for the P2X1 receptor. The Journal of Biological Chemistry. 279: 6426-33. PMID 14625300 DOI: 10.1074/Jbc.M306987200 |
0.489 |
|
2003 |
Hülsmann M, Nickel P, Kassack M, Schmalzing G, Lambrecht G, Markwardt F. NF449, a novel picomolar potency antagonist at human P2X1 receptors. European Journal of Pharmacology. 470: 1-7. PMID 12787824 DOI: 10.1016/S0014-2999(03)01761-8 |
0.443 |
|
2003 |
Rettinger J, Schmalzing G. Activation and desensitization of the recombinant P2X1 receptor at nanomolar ATP concentrations. The Journal of General Physiology. 121: 451-61. PMID 12719485 DOI: 10.1085/Jgp.200208730 |
0.454 |
|
2003 |
Failer BU, Aschrafi A, Schmalzing G, Zimmermann H. Determination of native oligomeric state and substrate specificity of rat NTPDase1 and NTPDase2 after heterologous expression in Xenopus oocytes. European Journal of Biochemistry. 270: 1802-9. PMID 12694193 DOI: 10.1046/J.1432-1033.2003.03542.X |
0.661 |
|
2003 |
Gendreau S, Schirmer J, Schmalzing G. Identification of a tubulin binding motif on the P2X2 receptor. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 786: 311-8. PMID 12651028 DOI: 10.1016/S1570-0232(02)00743-2 |
0.432 |
|
2003 |
Sadtler S, Laube B, Lashub A, Nicke A, Betz H, Schmalzing G. A basic cluster determines topology of the cytoplasmic M3-M4 loop of the glycine receptor alpha1 subunit. The Journal of Biological Chemistry. 278: 16782-90. PMID 12611885 DOI: 10.1074/Jbc.M213077200 |
0.306 |
|
2003 |
Nicke A, Rettinger J, Schmalzing G. Monomeric and dimeric byproducts are the principal functional elements of higher order P2X1 concatamers. Molecular Pharmacology. 63: 243-52. PMID 12488557 DOI: 10.1124/Mol.63.1.243 |
0.48 |
|
2003 |
Boldt W, Klapperstück M, Büttner C, Sadtler S, Schmalzing G, Markwardt F. Glu496Ala polymorphism of human P2X7 receptor does not affect its electrophysiological phenotype. American Journal of Physiology. Cell Physiology. 284: C749-56. PMID 12431909 DOI: 10.1152/Ajpcell.00042.2002 |
0.517 |
|
2001 |
Büttner C, Sadtler S, Leyendecker A, Laube B, Griffon N, Betz H, Schmalzing G. Ubiquitination precedes internalization and proteolytic cleavage of plasma membrane-bound glycine receptors. The Journal of Biological Chemistry. 276: 42978-85. PMID 11560918 DOI: 10.1074/Jbc.M102121200 |
0.418 |
|
2001 |
Braun K, Rettinger J, Ganso M, Kassack M, Hildebrandt C, Ullmann H, Nickel P, Schmalzing G, Lambrecht G. NF449: a subnanomolar potency antagonist at recombinant rat P2X1 receptors. Naunyn-Schmiedeberg's Archives of Pharmacology. 364: 285-90. PMID 11521173 DOI: 10.1007/S002100100463 |
0.476 |
|
2001 |
Horiuchi M, Nicke A, Gomeza J, Aschrafi A, Schmalzing G, Betz H. Surface-localized glycine transporters 1 and 2 function as monomeric proteins in Xenopus oocytes Proceedings of the National Academy of Sciences. 98: 1448-1453. DOI: 10.1073/Pnas.98.4.1448 |
0.645 |
|
2000 |
Klapperstück M, Büttner C, Böhm T, Schmalzing G, Markwardt F. Characteristics of P2X7 receptors from human B lymphocytes expressed in Xenopus oocytes. Biochimica Et Biophysica Acta. 1467: 444-456. PMID 11030601 DOI: 10.1016/S0005-2736(00)00245-5 |
0.49 |
|
2000 |
Rettinger J, Schmalzing G, Damer S, Müller G, Nickel P, Lambrecht G. The suramin analogue NF279 is a novel and potent antagonist selective for the P2X(1) receptor. Neuropharmacology. 39: 2044-53. PMID 10963748 DOI: 10.1016/S0028-3908(00)00022-8 |
0.399 |
|
2000 |
Rettinger J, Aschrafi A, Schmalzing G. Roles of individual N-glycans for ATP potency and expression of the rat P2X1 receptor. The Journal of Biological Chemistry. 275: 33542-7. PMID 10942758 DOI: 10.1074/Jbc.M002918200 |
0.723 |
|
2000 |
Lambrecht G, Rettinger J, Bäumert HG, Czeche S, Damer S, Ganso M, Hildebrandt C, Niebel B, Spatz-Kümbel G, Schmalzing G, Mutschler E. The novel pyridoxal-5'-phosphate derivative PPNDS potently antagonizes activation of P2X(1) receptors. European Journal of Pharmacology. 387: R19-21. PMID 10650184 DOI: 10.1016/S0014-2999(99)00834-1 |
0.453 |
|
2000 |
Klapperstück M, Büttner C, Nickel P, Schmalzing G, Lambrecht G, Markwardt F. Antagonism by the suramin analogue NF279 on human P2X1 and P2X7 receptors European Journal of Pharmacology. 387: 245-252. PMID 10650169 DOI: 10.1016/S0014-2999(99)00826-2 |
0.413 |
|
1999 |
Markwardt F, Klapperstück M, Löhn M, Riemann D, Büttner C, Schmalzing G. Purinoceptors in human B-lymphocytes. Progress in Brain Research. 120: 345-353. PMID 10551010 DOI: 10.1016/S0079-6123(08)63568-2 |
0.353 |
|
1999 |
Lambrecht G, Damer S, Niebel B, Czeche S, Nickel P, Rettinger J, Schmalzing G, Mutschler E. Novel ligands for P2 receptor subtypes in innervated tissues. Progress in Brain Research. 120: 107-17. PMID 10550991 DOI: 10.1016/S0079-6123(08)63549-9 |
0.436 |
|
1999 |
Nicke A, Rettinger J, Büttner C, Eichele A, Lambrecht G, Schmalzing G. Evolving view of quaternary structures of ligand-gated ion channels. Progress in Brain Research. 120: 61-80. PMID 10550988 DOI: 10.1016/S0079-6123(08)63546-3 |
0.464 |
|
1999 |
Griffon N, Büttner C, Nicke A, Kuhse J, Schmalzing G, Betz H. Molecular determinants of glycine receptor subunit assembly. The Embo Journal. 18: 4711-21. PMID 10469650 DOI: 10.1093/Emboj/18.17.4711 |
0.389 |
|
1999 |
Nicke A, Rettinger J, Mutschler E, Schmalzing G. Blue native PAGE as a useful method for the analysis of the assembly of distinct combinations of nicotinic acetylcholine receptor subunits. Journal of Receptor and Signal Transduction Research. 19: 493-507. PMID 10071780 DOI: 10.3109/10799899909036667 |
0.317 |
|
1998 |
Damer S, Niebel B, Czeche S, Nickel P, Ardanuy U, Schmalzing G, Rettinger J, Mutschler E, Lambrecht G. NF279: a novel potent and selective antagonist of P2X receptor-mediated responses. European Journal of Pharmacology. 350: R5-6. PMID 9683026 DOI: 10.1016/S0014-2999(98)00316-1 |
0.421 |
|
1998 |
Nicke A, Bäumert HG, Rettinger J, Eichele A, Lambrecht G, Mutschler E, Schmalzing G. P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels. The Embo Journal. 17: 3016-28. PMID 9606184 DOI: 10.1093/Emboj/17.11.3016 |
0.54 |
|
1995 |
Gloor S, Pongs O, Schmalzing G. A vector for the synthesis of cRNAs encoding Myc epitope-tagged proteins in Xenopus laevis oocytes. Gene. 160: 213-7. PMID 7543868 DOI: 10.1016/0378-1119(95)00226-V |
0.324 |
|
1991 |
Schmalzing G, Gloor S, Omay H, Kröner S, Appelhans H, Schwarz W. Up-regulation of sodium pump activity in Xenopus laevis oocytes by expression of heterologous beta 1 subunits of the sodium pump. The Biochemical Journal. 329-36. PMID 1719955 DOI: 10.1042/Bj2790329 |
0.376 |
|
1990 |
Schmalzing G, Eckard P, Kröner S, Passow H. Downregulation of surface sodium pumps by endocytosis during meiotic maturation of Xenopus laevis oocytes. The American Journal of Physiology. 258: C179-84. PMID 2154110 DOI: 10.1152/Ajpcell.1990.258.1.C179 |
0.33 |
|
Low-probability matches (unlikely to be authored by this person) |
2020 |
Richter K, Ogiemwonyi-Schaefer R, Wilker S, Chaveiro AI, Agné A, Hecker M, Reichert M, Amati AL, Schlüter KD, Manzini I, Schmalzing G, McIntosh JM, Padberg W, Grau V, Hecker A. Amyloid Beta Peptide (Aβ) Reverses the Cholinergic Control of Monocytic IL-1β Release. Journal of Clinical Medicine. 9. PMID 32906646 DOI: 10.3390/Jcm9092887 |
0.293 |
|
1994 |
Schmidt M, Kröger B, Jacob E, Seulberger H, Subkowski T, Otter R, Meyer T, Schmalzing G, Hillen H. Molecular characterization of human and bovine endothelin converting enzyme (ECE‐1) Febs Letters. 356: 238-243. PMID 7805846 DOI: 10.1016/0014-5793(94)01277-6 |
0.292 |
|
2007 |
Metz S, Wiesinger M, Vogt M, Lauks H, Schmalzing G, Heinrich PC, Müller-Newen G. Characterization of the Interleukin (IL)-6 Inhibitor IL-6-RFP: fused receptor domains act as high affinity cytokine-binding proteins. The Journal of Biological Chemistry. 282: 1238-48. PMID 17085445 DOI: 10.1074/Jbc.M606885200 |
0.278 |
|
1994 |
Schmalzing G, Gloor S. Na+/K+-Pump Beta Subunits: Structure and Functions Cellular Physiology and Biochemistry. 4: 96-114. DOI: 10.1159/000154715 |
0.276 |
|
1997 |
Schmalzing G, Ruhl K, Gloor SM. Isoform-specific interactions of Na,K-ATPase subunits are mediated via extracellular domains and carbohydrates. Proceedings of the National Academy of Sciences of the United States of America. 94: 1136-41. PMID 9037019 DOI: 10.1073/Pnas.94.4.1136 |
0.271 |
|
2023 |
Fischer L, Schmidt A, Dopychai A, Joussen S, Joeres N, Oslender-Bujotzek A, Schmalzing G, Gründer S. Physiologically relevant acid-sensing ion channel (ASIC) 2a/3 heteromers have a 1:2 stoichiometry. Communications Biology. 6: 701. PMID 37422581 DOI: 10.1038/s42003-023-05087-4 |
0.263 |
|
2010 |
Thyssen A, Hirnet D, Wolburg H, Schmalzing G, Deitmer JW, Lohr C. Ectopic vesicular neurotransmitter release along sensory axons mediates neurovascular coupling via glial calcium signaling. Proceedings of the National Academy of Sciences of the United States of America. 107: 15258-63. PMID 20696909 DOI: 10.1073/Pnas.1003501107 |
0.255 |
|
1989 |
Schmalzing G, Kröner S, Passow H. Evidence for intracellular sodium pumps in permeabilized Xenopus laevis oocytes. The Biochemical Journal. 260: 395-9. PMID 2548475 DOI: 10.1042/BJ2600395 |
0.244 |
|
2020 |
Ruehlmann A, Körner J, Bebrivenski N, Detro-Dassen S, Hautvast P, Benasolo C, Meents J, Machtens J, Schmalzing G, Lampert A. Functional Uncoupling of Pain-Linked Nav1.7/A1632E Dimers Partly Rescues Its Pain-Causing Phenotype Biophysical Journal. 118: 579a. DOI: 10.1016/J.Bpj.2019.11.3142 |
0.222 |
|
2021 |
Yang R, Li Z, Zou Y, Yang J, Li L, Xu X, Schmalzing G, Nie H, Li G, Liu S, Liang S, Xu C. Gallic Acid Alleviates Neuropathic Pain Behaviors in Rats by Inhibiting P2X7 Receptor-Mediated NF-κB/STAT3 Signaling Pathway. Frontiers in Pharmacology. 12: 680139. PMID 34512324 DOI: 10.3389/fphar.2021.680139 |
0.218 |
|
2021 |
Hausmann R, Franke H, Schmalzing G. How Prof. Burnstock's enthusiasm supported P2 receptor research in Germany. Purinergic Signalling. PMID 33543379 DOI: 10.1007/s11302-021-09768-9 |
0.217 |
|
2021 |
Grohmann M, Schumacher M, Günther J, Singheiser SM, Nußbaum T, Wildner F, Gerevich Z, Jabs R, Hirnet D, Lohr C, Illes P, Schmalzing G, Franke H, Hausmann R. BAC transgenic mice to study the expression of P2X2 and P2Y receptors. Purinergic Signalling. PMID 34050505 DOI: 10.1007/s11302-021-09792-9 |
0.217 |
|
1992 |
Pralong-Zamofing D, Yi QH, Schmalzing G, Good P, Geering K. Regulation of alpha 1-beta 3-NA(+)-K(+)-ATPase isozyme during meiotic maturation of Xenopus laevis oocytes. The American Journal of Physiology. 262: C1520-30. PMID 1377448 DOI: 10.1152/AJPCELL.1992.262.6.C1520 |
0.212 |
|
1991 |
Vasilets LA, Schmalzing G, Mädefessel K, Haase W, Schwarz W. Activation of protein kinase C by phorbol ester induces downregulation of the Na+/K(+)-ATPase in oocytes of Xenopus laevis. The Journal of Membrane Biology. 118: 131-42. PMID 2176238 DOI: 10.1007/BF01868470 |
0.21 |
|
2022 |
Xu X, Zhang H, Li L, Yang R, Li G, Liu S, Schmalzing G, Nie H, Liang S. Study of the Involvement of the P2Y12 Receptor in Chronic Itching in Type 2 Diabetes Mellitus. Molecular Neurobiology. PMID 35000152 DOI: 10.1007/s12035-021-02676-4 |
0.209 |
|
2023 |
Richter K, Asci N, Singh VK, Yakoob SH, Meixner M, Zakrzewicz A, Liese J, Hecker A, Wilker S, Stumpf S, Schlüter KD, Rohde M, Gödecke A, Padberg W, Manzini I, ... Schmalzing G, et al. Activation of endothelial NO synthase and P2X7 receptor modification mediates the cholinergic control of ATP-induced interleukin-1β release by mononuclear phagocytes. Frontiers in Immunology. 14: 1140592. PMID 36969210 DOI: 10.3389/fimmu.2023.1140592 |
0.206 |
|
2023 |
Grohs L, Cheng L, Cönen S, Haddad BG, Bülow A, Toklucu I, Ernst L, Körner J, Schmalzing G, Lampert A, Machtens JP, Hausmann R. Corrigendum: Diclofenac and other non-steroidal anti-inflammatory drugs (NSAIDs) are competitive antagonists of the human P2X3 receptor. Frontiers in Pharmacology. 14: 1225522. PMID 37332347 DOI: 10.3389/fphar.2023.1225522 |
0.193 |
|
1995 |
Schmalzing G, Richter HP, Hansen A, Schwarz W, Just I, Aktories K. Involvement of the GTP binding protein Rho in constitutive endocytosis in Xenopus laevis oocytes. The Journal of Cell Biology. 130: 1319-32. PMID 7559755 DOI: 10.1083/jcb.130.6.1319 |
0.192 |
|
1996 |
Appel C, Gloor S, Schmalzing G, Schachner M, Bernhardt RR. Expression of a Na,K-ATPase beta 3 subunit during development of the zebrafish central nervous system. Journal of Neuroscience Research. 46: 551-64. PMID 8951667 DOI: 10.1002/(SICI)1097-4547(19961201)46:5<551::AID-JNR4>3.0.CO;2-I |
0.19 |
|
2014 |
Schumacher M, Franke H, Hausmann R, Schmalzing G, Grohmann M. Characterisation of BAC transgenic TagRFP P2Y(1) reporter mice Purinergic Signalling. 10: 842-843. DOI: 10.1007/S11302-014-9430-7 |
0.186 |
|
1990 |
Schmalzing G, Kröner S. Micromolar free calcium exposes ouabain-binding sites in digitonin-permeabilized Xenopus laevis oocytes. The Biochemical Journal. 269: 757-66. PMID 2167664 DOI: 10.1042/BJ2690757 |
0.171 |
|
2021 |
Shi L, Sun M, Ren X, Li Z, Yang R, Xu X, Li L, Li G, Liu S, Schmalzing G, Nie H, Li G, Liang S. LncRNA UC.360+ shRNA Improves Diabetic Cardiac Sympathetic Dysfunction Mediated by the P2X4 Receptor in the Stellate Ganglion. Acs Chemical Neuroscience. PMID 33733741 DOI: 10.1021/acschemneuro.1c00050 |
0.161 |
|
1982 |
Schmalzing G, Kutschera P. Modulation of ATPase activities of human erythrocyte membranes by free fatty acids or phospholipase A2. The Journal of Membrane Biology. 69: 65-76. PMID 6126596 DOI: 10.1007/BF01871243 |
0.153 |
|
2001 |
Schmidt G, Goehring UM, Schirmer J, Uttenweiler-Joseph S, Wilm M, Lohmann M, Giese A, Schmalzing G, Aktories K. Lysine and polyamines are substrates for transglutamination of Rho by the Bordetella dermonecrotic toxin. Infection and Immunity. 69: 7663-70. PMID 11705946 DOI: 10.1128/IAI.69.12.7663-7670.2001 |
0.153 |
|
1985 |
Schmalzing G. Mechanism of depolarization of rat cortical synaptosomes at submicromolar external Ca2+ activity. The use of Ca2+ buffers to control the synaptosomal membrane potential. The Biochemical Journal. 225: 671-80. PMID 3977854 DOI: 10.1042/BJ2250671 |
0.15 |
|
1995 |
Mulner-Lorillon O, Bellé R, Cormier P, Drewing S, Minella O, Poulhe R, Schmalzing G. Brefeldin A provokes indirect activation of cdc2 kinase (MPF) in Xenopus oocytes, resulting in meiotic cell division. Developmental Biology. 170: 223-9. PMID 7541376 DOI: 10.1006/DBIO.1995.1209 |
0.143 |
|
2001 |
Klapperstück M, Schmalzing G, Markwardt F. Characteristics of binding sites for ATP4-at the human P2X7receptor Drug Development Research. 53: 77-82. DOI: 10.1002/DDR.1174 |
0.141 |
|
1981 |
Schmalzing G, Pfaff E, Breyer-Pfaff U. Red cell ouabain binding sites, Na+K+-ATPase, and intracellular Na+ as individual characteristics. Life Sciences. 29: 371-81. PMID 6268910 DOI: 10.1016/0024-3205(81)90330-1 |
0.123 |
|
1987 |
Schmalzing G. Proton permeability of the plasma membrane of rat cortical synaptosomes. European Journal of Biochemistry. 168: 27-35. PMID 2822404 DOI: 10.1111/J.1432-1033.1987.TB13382.X |
0.113 |
|
2023 |
Yang R, Shi L, Si H, Hu Z, Zou L, Li L, Xu X, Schmalzing G, Nie H, Li G, Liu S, Liang S, Xu C. Gallic Acid Improves Comorbid Chronic Pain and Depression Behaviors by Inhibiting P2X7 Receptor-Mediated Ferroptosis in the Spinal Cord of Rats. Acs Chemical Neuroscience. PMID 36719132 DOI: 10.1021/acschemneuro.2c00532 |
0.111 |
|
2000 |
Wilde C, Chhatwal GS, Schmalzing G, Aktories K, Just I. A novel C3-like ADP-ribosyltransferase from Staphylococcus aureus modifying RhoE and Rnd3. The Journal of Biological Chemistry. 276: 9537-42. PMID 11124969 DOI: 10.1074/jbc.M011035200 |
0.093 |
|
2007 |
Sýkora J, Kaiser K, Gregor I, Bönigk W, Schmalzing G, Enderlein J. Exploring fluorescence antibunching in solution to determine the stoichiometry of molecular complexes. Analytical Chemistry. 79: 4040-9. PMID 17487973 DOI: 10.1021/Ac062024F |
0.07 |
|
1978 |
Schmalzing G, Breyer U. Kinetics of [3H]trifluoperazine in bile fistula rats. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 8: 45-54. PMID 415442 DOI: 10.3109/00498257809060382 |
0.058 |
|
1990 |
Albert K, Rembold H, Kruppa G, Bayer E, Bartels M, Schmalzing G. In vivo 19F nuclear magnetic resonance spectroscopy of trifluorinated neuroleptics in the rat. Nmr in Biomedicine. 3: 120-3. PMID 2386658 DOI: 10.1002/NBM.1940030304 |
0.055 |
|
2010 |
Thyssen A, Hirnet D, Wolburg H, Schmalzing G, Deitmer JW, Lohr C. Ectopic vesicular neurotransmitter release along sensory axons mediates neurovascular coupling via glial calcium signaling Proceedings of the National Academy of Sciences of the United States of America. 107: 15258-15263. DOI: 10.1073/pnas.1003501107 |
0.048 |
|
1990 |
Sakmann B, Schrader J, Brenner B, Murer H, Boeckh J, Handwerker HO, HonerjÄger P, Dugas M, Wang G, DeLuca A, Brinkmeier H, Fakler B, Pröbstle T, Rüdel R, Pohl J-, ... ... Schmalzing G, et al. Abstract of the 68th Meeting (Spring Meeting) 6–9 March 1990, Heidelberg PflüGers Archiv. 415: R1-R119. DOI: 10.1007/Bf02912664 |
0.015 |
|
Hide low-probability matches. |