Yumiko Sakurai - Publications

Affiliations: 
Georgia Institute of Technology, Atlanta, GA 
Area:
Vascular biology, Cellular Engineering

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Sun Y, Myers DR, Nikolov SV, Oshinowo O, Baek J, Bowie SM, Lambert TP, Woods E, Sakurai Y, Lam WA, Alexeev A. Platelet heterogeneity enhances blood clot volumetric contraction: An example of asynchrono-mechanical amplification. Biomaterials. 274: 120828. PMID 33964792 DOI: 10.1016/j.biomaterials.2021.120828  0.309
2020 Oshinowo O, Lambert T, Sakurai Y, Copeland R, Hansen CE, Lam WA, Myers DR. Getting a good view: imaging of platelets under flow. Platelets. 1-10. PMID 32106734 DOI: 10.1080/09537104.2020.1732320  0.415
2019 Qiu Y, Sakurai Y, Lam WA. Monitoring the "Lifetime" of a Thrombus over Long Timescales By Leveraging a Novel Microvasculature-on-Chip Thrombosis Resolution Assay Blood. 134: 441-441. DOI: 10.1182/Blood-2019-128718  0.465
2019 Caruso C, Zhang X, Sakurai Y, Li W, Fay ME, Carden MA, Myers DR, Mannino RG, Joiner CH, Graham MD, Lam WA. Stiff Erythrocyte Subpopulations Biomechanically Induce Endothelial Inflammation in Sickle Cell Disease Blood. 134: 3560-3560. DOI: 10.1182/Blood-2019-125408  0.414
2018 Qiu Y, Ahn B, Sakurai Y, Hansen C, Tran R, Mimche PN, Mannino R, Ciciliano JC, Lamb TJ, Joiner CH, Ofori-Acquah SF, Lam WA. Microvasculature-on-a-chip for the long-term study of endothelial barrier dysfunction and microvascular obstruction in disease. Nature Biomedical Engineering. 2: 453-463. PMID 30533277 DOI: 10.1038/S41551-018-0224-Z  0.342
2018 Hardy ET, Wang YJ, Iyer S, Mannino RG, Sakurai Y, Barker TH, Chi T, Youn Y, Wang H, Brown AC, Lam WA. Interdigitated microelectronic bandage augments hemostasis and clot formation at low applied voltage in vitro and in vivo. Lab On a Chip. PMID 30109316 DOI: 10.1039/C8Lc00573G  0.317
2018 Sakurai Y, Hardy ET, Ahn B, Tran R, Fay ME, Ciciliano JC, Mannino RG, Myers DR, Qiu Y, Carden MA, Baldwin WH, Meeks SL, Gilbert GE, Jobe SM, Lam WA. A microengineered vascularized bleeding model that integrates the principal components of hemostasis. Nature Communications. 9: 509. PMID 29410404 DOI: 10.1038/S41467-018-02990-X  0.44
2018 Kholmukhamedov A, Sakurai Y, Hardy EL, Lam WA, Jobe SM. Mitochondrial Uncoupling Prevents Procoagulant Platelet Formation Resulting in Decreased Thrombus Stability Blood. 132: 2421-2421. DOI: 10.1182/Blood-2018-99-117004  0.42
2018 Copeland R, Oshinowo OT, Sakurai Y, Fay ME, Petrich BG, Brainard B, Lam WA, Myers DR. A Comparative Medicine Study of Platelet Biophysics Among Hemostasis Models of Different Species Blood. 132: 869-869. DOI: 10.1182/Blood-2018-99-113107  0.421
2017 Carden MA, Fay ME, Lu X, Mannino RG, Sakurai Y, Ciciliano JC, Hansen CE, Chonat S, Joiner CH, Wood DK, Lam WA. Impact of extracellular fluid tonicity on sickle red blood cell deformability and adhesion. Blood. PMID 28978568 DOI: 10.1182/Blood-2017-04-780635  0.365
2017 Hansen CE, Myers DR, Baldwin WH, Sakurai Y, Meeks SL, Lyon LA, Lam WA. Platelet-Microcapsule Hybrids Leverage Contractile Force for Targeted Delivery of Hemostatic Agents. Acs Nano. PMID 28541681 DOI: 10.1021/Acsnano.7B00929  0.411
2017 Carden MA, Fay M, Sakurai Y, McFarland B, Blanche S, Diprete C, Joiner CH, Sulchek T, Lam WA. Normal Saline is Associated with Increased Sickle Red Cell Stiffness and Prolonged Transit Times in a Microfluidic Model of the Capillary System. Microcirculation (New York, N.Y. : 1994). PMID 28106307 DOI: 10.1111/Micc.12353  0.336
2016 Myers DR, Qiu Y, Fay ME, Tennenbaum M, Chester D, Cuadrado J, Sakurai Y, Baek J, Tran R, Ciciliano JC, Ahn B, Mannino RG, Bunting ST, Bennett C, Briones M, et al. Single-platelet nanomechanics measured by high-throughput cytometry. Nature Materials. PMID 27723740 DOI: 10.1038/Nmat4772  0.445
2016 Fay ME, Myers DR, Kumar A, Turbyfield CT, Byler R, Crawford K, Mannino RG, Laohapant A, Tyburski EA, Sakurai Y, Rosenbluth MJ, Switz NA, Sulchek TA, Graham MD, Lam WA. Cellular softening mediates leukocyte demargination and trafficking, thereby increasing clinical blood counts. Proceedings of the National Academy of Sciences of the United States of America. PMID 26858400 DOI: 10.1073/Pnas.1508920113  0.377
2016 Hansen CE, Myers DR, Sakurai Y, Baldwin WH, Meeks SL, Lyon LA, Lam WA. Leveraging the Contractile Force of Platelets for Targeted Factor VIII Delivery in Hemophilia with Inhibitors Blood. 128: 81-81. DOI: 10.1182/Blood.V128.22.81.81  0.414
2015 Sakurai Y, Fitch-Tewfik JL, Qiu Y, Ahn B, Myers DR, Tran R, Fay ME, Ding L, Spearman PW, Michelson AD, Flaumenhaft R, Lam WA. Platelet geometry sensing spatially regulates α-granule secretion to enable matrix self-deposition. Blood. 126: 531-8. PMID 25964667 DOI: 10.1182/Blood-2014-11-607614  0.406
2015 Ciciliano JC, Sakurai Y, Myers DR, Fay ME, Hechler B, Meeks S, Li R, Dixon JB, Lyon LA, Gachet C, Lam WA. Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach. Blood. PMID 25931587 DOI: 10.1182/Blood-2015-02-628594  0.399
2015 Kee MF, Myers DR, Sakurai Y, Lam WA, Qiu Y. Platelet mechanosensing of collagen matrices. Plos One. 10: e0126624. PMID 25915413 DOI: 10.1182/Blood.V124.21.1437.1437  0.441
2015 Tran R, Myers DR, Shields JE, Ahn B, Qiu Y, Hansen C, Sakurai Y, Moot R, Spencer HT, Doering CB, Lam WA. Improving Lentiviral Transduction Efficiency with Microfluidic Systems Blood. 126: 4415-4415. DOI: 10.1182/Blood.V126.23.4415.4415  0.343
2015 Sakurai Y, Hardy ET, Ahn B, Meeks SL, Baldwin WH, Jobe SM, Lam WA. Engineering a Valve-Regulated Endothelialized Microfluidic Device As an "in Vitro" Bleeding Time for Assessing Global Hemostasis Blood. 126: 3485-3485. DOI: 10.1182/Blood.V126.23.3485.3485  0.416
2015 Rollins MR, Ahn B, Sakurai Y, Lam WA. Characterizing Cellular Interactions Contributing to Vaso-Occlusion in Patients with Sickle Cell Disease Utilizing a Novel Endothelialized Microfluidic Device Blood. 126: 3381-3381. DOI: 10.1182/Blood.V126.23.3381.3381  0.483
2015 Qiu Y, Ahn B, Sakurai Y, Hansen C, Joiner CH, Ofori-Acquah SF, Lam WA. Engineering a "Self-Healing" Hydrogel-Based Microvasculature-on-a-Chip for Investigating the Effects of Cellular and Biomolecular Interactions on Endothelial Permeability in Sickle Cell Disease Blood. 126: 240-240. DOI: 10.1182/Blood.V126.23.240.240  0.405
2015 Carden MA, Fay ME, Sakurai Y, Mannino RG, Ciciliano J, Tran R, Lam WA. Commonly Used Clinical Intravenous Fluid Formulations Differentially Affect Sickle Red Blood Cell Stiffness and Transit Time Blood. 126: 2164-2164. DOI: 10.1182/Blood.V126.23.2164.2164  0.345
2014 Tran R, Ahn B, R Myers D, Qiu Y, Sakurai Y, Moot R, Mihevc E, Trent Spencer H, Doering C, A Lam W. Simplified prototyping of perfusable polystyrene microfluidics. Biomicrofluidics. 8: 046501. PMID 25379106 DOI: 10.1063/1.4892035  0.336
2014 Qiu Y, Brown AC, Myers DR, Sakurai Y, Mannino RG, Tran R, Ahn B, Hardy ET, Kee MF, Kumar S, Bao G, Barker TH, Lam WA. Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 14430-5. PMID 25246564 DOI: 10.1073/Pnas.1322917111  0.43
2014 Chinnadurai R, Garcia MA, Sakurai Y, Lam WA, Kirk AD, Galipeau J, Copland IB. Actin cytoskeletal disruption following cryopreservation alters the biodistribution of human mesenchymal stromal cells in vivo. Stem Cell Reports. 3: 60-72. PMID 25068122 DOI: 10.1016/J.Stemcr.2014.05.003  0.313
2014 Ciciliano JC, Tran R, Sakurai Y, Lam WA. The platelet and the biophysical microenvironment: lessons from cellular mechanics. Thrombosis Research. 133: 532-7. PMID 24440140 DOI: 10.1016/J.Thromres.2013.12.037  0.44
2014 Rollins MR, Ahn B, Sakurai Y, Ciciliano JC, Lam WA. Investigating Platelet Interactions in Sickle Cell Disease Using a Novel Multi-Shear "Endothelialized" Microfluidic System Blood. 124: 4155-4155. DOI: 10.1182/Blood.V124.21.4155.4155  0.483
2014 Sakurai Y, Fitch-Tewfik JL, Qiu Y, Myers DR, Ahn B, Flaumenhaft R, Lam WA. “Self-Deposition” of Matrix Proteins from Platelet α-Granules Enable Extended Adhesion and Spreading on Micron/Submicron-Scale Fibrinogen and Collagen Substrates. Blood. 124: 2764-2764. DOI: 10.1182/Blood.V124.21.2764.2764  0.431
2014 Qiu Y, Brown AC, Myers DR, Sakurai Y, Mannino R, Tran R, Ahn B, Hardy E, Kee MF, Kumar S, Bao G, Barker TH, Lam WA. Platelet Adhesion, Spreading and Activation Are Mediated By Mechanosensing of Matrix Stiffness Blood. 124: 1438-1438. DOI: 10.1182/Blood.V124.21.1438.1438  0.447
2013 Tran R, Myers DR, Ciciliano J, Trybus Hardy EL, Sakurai Y, Ahn B, Qiu Y, Mannino RG, Fay ME, Lam WA. Biomechanics of haemostasis and thrombosis in health and disease: from the macro- to molecular scale. Journal of Cellular and Molecular Medicine. 17: 579-96. PMID 23490277 DOI: 10.1111/Jcmm.12041  0.394
2013 Ciciliano JC, Myers DR, Fay ME, Sakurai Y, Li R, Lyon A, Lam WA. New Insights Into The Mechanisms Of Ferric Chloride-Induced Thrombosis: a Reductionist Microfluidic Approach Blood. 122: 2308-2308. DOI: 10.1182/Blood.V122.21.2308.2308  0.448
2012 Myers DR, Sakurai Y, Tran R, Ahn B, Hardy ET, Mannino R, Kita A, Tsai M, Lam WA. Endothelialized microfluidics for studying microvascular interactions in hematologic diseases. Journal of Visualized Experiments : Jove. PMID 22760254 DOI: 10.3791/3958  0.411
2012 Mannino R, Myers DR, Sakurai Y, Ware RE, Barabino G, Lam W. Increased Erythrocyte Rigidity Is Sufficient to Cause Endothelial Dysfunction in Sickle Cell Disease Blood. 120: 818-818. DOI: 10.1182/Blood.V120.21.818.818  0.411
2012 Qiu Y, Brown AC, Jung WJ, Sakurai Y, Mannino R, Myers DR, Tran R, Bao G, Barker TH, Lam W. Platelet Mechanosensing: Adhesion and Spreading On Immobilized Fibrinogen Depends On Substrate Stiffness Blood. 120: 384-384. DOI: 10.1182/Blood.V120.21.384.384  0.432
2012 Tran R, Ahn B, Myers DR, Qiu Y, Sakurai Y. Spatial Regulation of Platelet Aggregation and Physiology Under Flow Blood. 120: 3300-3300. DOI: 10.1182/Blood.V120.21.3300.3300  0.441
2012 Hardy E, Sakurai Y, Sanjaya N, Wolberg AS, Lam W. Effect of Locally Applied Electricity On Clot Formation and Hemostasis. Blood. 120: 2220-2220. DOI: 10.1182/Blood.V120.21.2220.2220  0.404
2012 Myers DR, Brown AC, Qiu Y, Sakurai Y, Tran R, Ahn B, Mannino R, Sulchek T, Lyon A, Barker TH, Lam W. High-Throughput Nanomechanical Platelet Contraction Measurements Using Patterned Hydrogels. Blood. 120: 2172-2172. DOI: 10.1182/Blood.V120.21.2172.2172  0.437
2012 Sakurai Y, Qiu Y, Ahn B, Lam W. Platelet α-Granule Secretion and Cytoskeletal Rearrangements Are Spatially Regulated At the Micro/Nanoscale. Blood. 120: 2163-2163. DOI: 10.1182/Blood.V120.21.2163.2163  0.431
2012 Ahn B, Sakurai Y, Myers DR, Qiu Y, Hardy E, Tran R, Mannino R, Wolberg AS, Lam W. An “Endothelialized” Microfluidic System That Distinguishes Procoagulant Mechanisms in Arterial and Venous Thrombosis Blood. 120: 1071-1071. DOI: 10.1182/Blood.V120.21.1071.1071  0.413
2011 Kita A, Sakurai Y, Myers DR, Rounsevell R, Huang JN, Seok TJ, Yu K, Wu MC, Fletcher DA, Lam WA. Microenvironmental geometry guides platelet adhesion and spreading: a quantitative analysis at the single cell level. Plos One. 6: e26437. PMID 22028878 DOI: 10.1371/Journal.Pone.0026437  0.423
2011 Myers DR, Sakurai Y, Chappa P, Barabino G, Archer DR, Lam W. Measuring the Direct Effects of Sickle Cell Vaso-Occlusion on Endothelial Cells Using Microfluidic Technology Blood. 118: 897-897. DOI: 10.1182/Blood.V118.21.897.897  0.406
2011 Sakurai Y, Myers DR, Kita A, Lam W. A Novel Assay That Integrates the Effects of Multiple Agonists At the Single-Platelet Level, Blood. 118: 3258-3258. DOI: 10.1182/Blood.V118.21.3258.3258  0.434
2011 Kita A, Sakurai Y, Myers DR, Rounsevell R, Seok TJ, Yu K, Huang J, Wu M, Fletcher D, Lam W. Platelet Sensing of Microenviornmental Geometry Guides Adhesion and Spreading: A Quantitative Study At the Single-Cell Level Blood. 118: 2192-2192. DOI: 10.1182/Blood.V118.21.2192.2192  0.442
2009 Conway DE, Sakurai Y, Weiss D, Vega JD, Taylor WR, Jo H, Eskin SG, Marcus CB, McIntire LV. Expression of CYP1A1 and CYP1B1 in human endothelial cells: regulation by fluid shear stress. Cardiovascular Research. 81: 669-77. PMID 19126602 DOI: 10.1093/Cvr/Cvn360  0.319
2008 Williams MR, Kataoka N, Sakurai Y, Powers CM, Eskin SG, McIntire LV. Gene expression of endothelial cells due to interleukin-1 beta stimulation and neutrophil transmigration Endothelium: Journal of Endothelial Cell Research. 15: 73-84. PMID 18568947 DOI: 10.1080/10623320802092443  0.326
2006 Yee A, Sakurai Y, Eskin SG, McIntire LV. A validated system for simulating common carotid arterial flow in vitro: alteration of endothelial cell response. Annals of Biomedical Engineering. 34: 593-604. PMID 16565786 DOI: 10.1007/s10439-006-9078-8  0.311
2005 Sung HJ, Eskin SG, Sakurai Y, Yee A, Kataoka N, McIntire LV. Oxidative stress produced with cell migration increases synthetic phenotype of vascular smooth muscle cells. Annals of Biomedical Engineering. 33: 1546-54. PMID 16341922 DOI: 10.1007/S10439-005-7545-2  0.322
2004 Kim SH, Lessner SM, Sakurai Y, Galis ZS. Cyclophilin A as a novel biphasic mediator of endothelial activation and dysfunction. The American Journal of Pathology. 164: 1567-74. PMID 15111303 DOI: 10.1016/S0002-9440(10)63715-7  0.364
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