Brian Y Lam, PhD - Related publications

Affiliations: 
University of Cambridge, Cambridge, England, United Kingdom 
Area:
Genomics
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Park BS, Im HL, Yoon NA, Tu TH, Park JW, Kim JG, Lee BJ. Developmentally regulated GTP-binding protein-2 regulates adipocyte differentiation. Biochemical and Biophysical Research Communications. 578: 1-6. PMID 34520979 DOI: 10.1016/j.bbrc.2021.08.081   
2021 Jouvet N, Bouyakdan K, Campbell SA, Baldwin C, Townsend SE, Gannon MA, Poitout V, Alquier T, Estall JL. The Tetracycline-Controlled Transactivator (Tet-On/Off) System in Beta Cells Reduces Insulin Expression and Secretion in Mice. Diabetes. PMID 34610983 DOI: 10.2337/db21-0147   
2021 Zhang H, Qian M, Wang J, Yang G, Weng Y, Jin C, Li Y, Jin Y. Insights into the effects of difenoconazole on the livers in male mice at the biochemical and transcriptomic levels. Journal of Hazardous Materials. 422: 126933. PMID 34425431 DOI: 10.1016/j.jhazmat.2021.126933   
2021 Park SS, Lim SK, Lee J, Park HK, Kwon MS, Yun M, Kim N, Oh YJ, Choi HJ. WIKIM31 decelerates weight gain in high-fat diet-induced obese mice by modulating lipid metabolism and suppressing inflammation. Journal of Microbiology and Biotechnology. 31. PMID 34528915 DOI: 10.4014/jmb.2107.07024   
2021 Xiang X, Zhou X, Wang W, Zhou Y, Zhou X, Deng S, Zheng B, Wen Z. Effect of Antarctic krill phospholipid (KOPL) on high fat diet-induced obesity in mice. Food Research International (Ottawa, Ont.). 148: 110456. PMID 34507719 DOI: 10.1016/j.foodres.2021.110456   
2021 Li M, Shao F, Qian Q, Yu W, Zhang Z, Chen B, Su D, Guo Y, Phan AV, Song LS, Stephens SB, Sebag J, Imai Y, Yang L, Cao H. A putative long noncoding RNA-encoded micropeptide maintains cellular homeostasis in pancreatic β cells. Molecular Therapy. Nucleic Acids. 26: 307-320. PMID 34513312 DOI: 10.1016/j.omtn.2021.06.027   
2021 Zhang D, Yamaguchi S, Zhang X, Yang B, Kurooka N, Sugawara R, Albuayjan HHH, Nakatsuka A, Eguchi J, Hiyama TY, Kamiya A, Wada J. Upregulation of in Diet-Induced Obesity Mouse and the Hypothalamic Appetite Control. Frontiers in Endocrinology. 12: 727915. PMID 34526970 DOI: 10.3389/fendo.2021.727915   
2021 Igel E, Haller A, Wolfkiel PR, Orr-Asman M, Jaeschke A, Hui DY. Distinct pro-inflammatory properties of myeloid cell-derived apolipoprotein E2 and E4 in atherosclerosis promotion. The Journal of Biological Chemistry. 101106. PMID 34425108 DOI: 10.1016/j.jbc.2021.101106   
2021 Burchat N, Sharma P, Ye H, Komakula SSB, Dobrzyn A, Vartanian V, Lloyd RS, Sampath H. Maternal Transmission of Human OGG1 Protects Mice Against Genetically- and Diet-Induced Obesity Through Increased Tissue Mitochondrial Content. Frontiers in Cell and Developmental Biology. 9: 718962. PMID 34604220 DOI: 10.3389/fcell.2021.718962   
2021 Kuang X, McAndrew MJ, Mustachio LM, Chen YC, Atanassov BS, Lin K, Lu Y, Shen J, Salinger A, Macatee T, Dent SYR, Koutelou E. Overexpression Leads to Aberrant Signal Transduction of Cancer-Related Pathways but Is Not Sufficient to Drive Tumor Formation in Mice. Cancers. 13. PMID 34503086 DOI: 10.3390/cancers13174276   
2021 Wang W, Chen D, Piao H. [Identification of -regulated metabolites using ultra-performance liquid chromatography coupled with time-of-flight mass spectrometry in malignant transformation of liver inflammation]. SE Pu = Chinese Journal of Chromatography. 39: 1118-1127. PMID 34505434 DOI: 10.3724/SP.J.1123.2021.06006   
2021 Paterlini S, Panelli R, Gioiosa L, Parmigiani S, Franceschini P, Bertocchi I, Oberto A, Bartolomucci A, Eva C, Palanza P. Conditional Inactivation of Limbic Neuropeptide Y-1 Receptors Increases Vulnerability to Diet-Induced Obesity in Male Mice. International Journal of Molecular Sciences. 22. PMID 34445453 DOI: 10.3390/ijms22168745   
2021 Longenecker JZ, Petrosino JM, Martens CR, Hinger SA, Royer CJ, Dorn LE, Branch DA, Serrano J, Stanford KI, Kyriazis GA, Baskin KK, Accornero F. Cardiac-derived TGF-β1 confers resistance to diet-induced obesity through regulation of adipocyte size and function. Molecular Metabolism. 101343. PMID 34583010 DOI: 10.1016/j.molmet.2021.101343   
2021 Chun HJ, Shim YJ, Kwon YH. Cholic acid supplementation accelerates the progression of nonalcoholic fatty liver disease to the procarcinogenic state in mice fed a high-fat and high-cholesterol diet. The Journal of Nutritional Biochemistry. 108869. PMID 34563665 DOI: 10.1016/j.jnutbio.2021.108869   
2021 Li K, Feng T, Liu L, Liu H, Huang K, Zhou J. Hepatic Proteomic Analysis of Selenoprotein T Knockout Mice by TMT: Implications for the Role of Selenoprotein T in Glucose and Lipid Metabolism. International Journal of Molecular Sciences. 22. PMID 34445217 DOI: 10.3390/ijms22168515   
2021 Takaoka S, Yanagiya A, Mohamed HMA, Higa R, Abe T, Inoue KI, Takahashi A, Stoney P, Yamamoto T. Neuronal XRN1 is required for maintenance of whole-body metabolic homeostasis. Iscience. 24: 103151. PMID 34646989 DOI: 10.1016/j.isci.2021.103151   
2021 Ballasy NN, Jadli AS, Edalat P, Kang S, Fatehi Hassanabad A, Gomes KP, Fedak PWM, Patel VB. Potential role of epicardial adipose tissue in coronary artery endothelial cell dysfunction in type 2 diabetes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21878. PMID 34469050 DOI: 10.1096/fj.202100684RR   
2021 Jin L, Li Q, Li J, Pan Y, Zou J, Wu X, Wang Z. Apela inhibits systemic and renal inflammatory reactions in mice with type I cardiorenal syndrome. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21907. PMID 34516679 DOI: 10.1096/fj.202101030R   
2021 Choi HN, Shin JY, Kim JI. Ameliorative Effect of Myricetin on Nonalcoholic Fatty Liver Disease in Mice. Journal of Medicinal Food. 24: 1092-1099. PMID 34668765 DOI: 10.1089/jmf.2021.K.0090   
2021 Park YJ, Seo MG, Cominguez DC, Han I, An HJ. Water Extract Ameliorates Obesity via Promotion of the SIRT1/AMPK Expression in High-Fat Diet-Induced Obese Mice. Nutrients. 13. PMID 34578872 DOI: 10.3390/nu13092992   
2021 Hua J, Gao Z, Zhong S, Wei B, Zhu J, Ying R. CISD1 protects against atherosclerosis by suppressing lipid accumulation and inflammation via mediating Drp1. Biochemical and Biophysical Research Communications. 577: 80-88. PMID 34509082 DOI: 10.1016/j.bbrc.2021.08.023   
2021 Muturi HT, Khuder SS, Ghadieh HE, Esakov EL, Noh H, Kang H, McInerney MF, Kim JK, Lee AD, Najjar SM. Insulin Sensitivity Is Retained in Mice with Endothelial Loss of Carcinoembryonic Antigen Cell Adhesion Molecule 1. Cells. 10. PMID 34440862 DOI: 10.3390/cells10082093   
2021 Shu L, Hou X, Song G, Wang C, Ma H. Comparative analysis of long non‑coding RNA expression profiles induced by resveratrol and metformin treatment for hepatic insulin resistance. International Journal of Molecular Medicine. 48. PMID 34581420 DOI: 10.3892/ijmm.2021.5039   
2021 He Z, Lieu L, Dong Y, Afrin S, Chau D, Kabahizi A, Wallace B, Cao J, Hwang ES, Yao T, Huang Y, Okolo J, Cheng B, Gao Y, Hu L, et al. PERK in POMC neurons connects celastrol with metabolism. Jci Insight. 6. PMID 34549728 DOI: 10.1172/jci.insight.145306   
2021 Yamaguchi K, Hayashi M, Uchida Y, Cheng XW, Nakayama T, Matsushita T, Murohara T, Takeshita K. Notch1 haploinsufficiency in mice accelerates adipogenesis. Scientific Reports. 11: 16761. PMID 34408185 DOI: 10.1038/s41598-021-96017-z   
2021 Liu Y, Li YQ, Huang SH, Li YL, Xia JW, Jia JS, Wei F, Wang JH, Dai GQ, Wang YC, Li XY, Han LX, Zhang XL, Xiang XD, Zhao WT, et al. Liver-specific over-expression of Cripto-1 in transgenic mice promotes hepatocyte proliferation and deregulated expression of hepatocarcinogenesis-related genes and signaling pathways. Aging. 13. PMID 34517344 DOI: 10.18632/aging.203402   
2021 Li H, Quan F, Zhang P, Shao Y. Long non-coding RNA SNHG16, binding with miR-106b-5p, promoted cell apoptosis and inflammation in allergic rhinitis by up-regulating leukemia inhibitory factor to activate the JAK1/STAT3 signaling pathway. Human & Experimental Toxicology. 9603271211035665. PMID 34407675 DOI: 10.1177/09603271211035665   
2021 Gluais-Dagorn P, Foretz M, Steinberg GR, Batchuluun B, Zawistowska-Deniziak A, Lambooij JM, Guigas B, Carling D, Monternier PA, Moller DE, Bolze S, Hallakou-Bozec S. Direct AMPK Activation Corrects NASH in Rodents Through Metabolic Effects and Direct Action on Inflammation and Fibrogenesis. Hepatology Communications. PMID 34494384 DOI: 10.1002/hep4.1799   
2021 Zuccaro A, Zapatería B, Sánchez-Alonso MG, Haro M, Limones M, Terrados G, Izquierdo A, Corrales P, Medina-Gómez G, Herradón G, Sevillano J, Ramos-Álvarez MDP. Pleiotrophin Deficiency Induces Browning of Periovarian Adipose Tissue and Protects against High-Fat Diet-Induced Hepatic Steatosis. International Journal of Molecular Sciences. 22. PMID 34502170 DOI: 10.3390/ijms22179261   
2021 Tu C, Xu Z, Tian L, Yu Z, Wang T, Guo Z, Zhang J, Wang T. Multi-Omics Integration to Reveal the Mechanism of Hepatotoxicity Induced by Dictamnine. Frontiers in Cell and Developmental Biology. 9: 700120. PMID 34595163 DOI: 10.3389/fcell.2021.700120   
2021 Collier JJ, Batdorf HM, Merrifield KL, Martin TM, White U, Ravussin E, Burk DH, Cooley CR, Karlstad MD, Burke SJ. Pioglitazone Reverses Markers of Islet Beta-Cell De-Differentiation in Mice While Modulating Expression of Genes Controlling Inflammation and Browning in White Adipose Tissue from Insulin-Resistant Mice and Humans. Biomedicines. 9. PMID 34572374 DOI: 10.3390/biomedicines9091189   
2021 Yang R, Yin D, Yang D, Liu X, Zhou Q, Pan Y, Li J, Li S. Xinnaokang improves cecal microbiota and lipid metabolism to target atherosclerosis. Letters in Applied Microbiology. PMID 34596907 DOI: 10.1111/lam.13573   
2021 Zhao C, Cui X, Zhao Y, Qian B, Zhang N, Xin L, Ha C, Yang J, Wang X, Gao X. Impact of hepatocyte-specific deletion of staphylococcal nuclease and tudor domain containing 1 (SND1) on liver insulin resistance and acute liver failure of mice. Bioengineered. 12: 7360-7375. PMID 34608846 DOI: 10.1080/21655979.2021.1974653   
2021 Li Y, Qi W, Yan L, Wang M, Zhao L. derivative LLDT-8 targets CD2 in the treatment of rheumatoid arthritis. Biomedical Reports. 15: 81. PMID 34429967 DOI: 10.3892/br.2021.1457   
2021 Zhang Y, Wang O, Ma N, Yi J, Mi H, Cai S. The preventive effect and underlying mechanism of Mill. fruits on dextran sulphate sodium-induced ulcerative colitis in mice. Food & Function. PMID 34494061 DOI: 10.1039/d1fo01558c   
2021 Chen HB, Pineda Garcia JC, Arizono S, Takeda T, Li RS, Hattori Y, Sano H, Miyauchi Y, Hirota Y, Tanaka Y, Ishii Y. DAPL1 is a novel regulator of testosterone production in Leydig cells of mouse testis. Scientific Reports. 11: 18532. PMID 34535743 DOI: 10.1038/s41598-021-97961-6   
2021 Snyder MM, Yue F, Zhang L, Shang R, Qiu J, Chen J, Kim KH, Peng Y, Oprescu SN, Donkin SS, Bi P, Kuang S. LETMD1 is required for mitochondrial structure and thermogenic function of brown adipocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21965. PMID 34669999 DOI: 10.1096/fj.202100597R   
2021 Lee HJ, Shi H, Brönneke HS, Jin BY, Choi SH, Seeley RJ, Kim DH. Vascular reactivity contributes to adipose tissue remodeling in obesity. The Journal of Endocrinology. PMID 34612845 DOI: 10.1530/JOE-21-0187   
2021 Lima RP, Nunes PIG, Viana AFSC, Oliveira FTB, Silva RAC, Alves APNN, Viana DA, Fonseca SGC, Carvalho AA, Chaves MH, Rao VS, Santos FA. α,β-Amyrin prevents steatosis and insulin resistance in a high-fat diet-induced mouse model of NAFLD via the AMPK-mTORC1-SREBP1 signaling mechanism. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas. 54: e11391. PMID 34406209 DOI: 10.1590/1414-431X2021e11391   
2021 Song H, Shen X, Zhou Y, Zheng X. Black rice anthocyanins alleviate hyperlipidemia, liver steatosis and insulin resistance by regulating lipid metabolism and gut microbiota in obese mice. Food & Function. PMID 34528983 DOI: 10.1039/d1fo01394g   
2021 Li Z, Wang H, Wu K, Zhang L. Omarigliptin protects against nonalcoholic fatty liver disease by ameliorating oxidative stress and inflammation. Journal of Biochemical and Molecular Toxicology. e22914. PMID 34533252 DOI: 10.1002/jbt.22914   
2021 Su CT, Jao TM, Urban Z, Huang YJ, See DHW, Tsai YC, Lin WC, Huang JW. LTBP4 affects renal fibrosis by influencing angiogenesis and altering mitochondrial structure. Cell Death & Disease. 12: 943. PMID 34645813 DOI: 10.1038/s41419-021-04214-5   
2021 Maksimowski NA, Song X, Bae EH, Reich H, John R, Pei Y, Scholey JW, Nephrotic Syndrome Study Network Neptune. Follistatin-Like-1 (FSTL1) Is a Fibroblast-Derived Growth Factor That Contributes to Progression of Chronic Kidney Disease. International Journal of Molecular Sciences. 22. PMID 34502419 DOI: 10.3390/ijms22179513   
2021 Sun W, Byon CH, Kim DH, Choi HI, Park JS, Joo SY, Kim IJ, Jung I, Bae EH, Ma SK, Kim SW. Renoprotective Effects of Maslinic Acid on Experimental Renal Fibrosis in Unilateral Ureteral Obstruction Model via Targeting MyD88. Frontiers in Pharmacology. 12: 708575. PMID 34588982 DOI: 10.3389/fphar.2021.708575   
2021 Truchan NA, Fenske RJ, Sandhu HK, Weeks AM, Patibandla C, Wancewicz B, Pabich S, Reuter A, Harrington JM, Brill AL, Peter DC, Nall R, Daniels M, Punt M, Kaiser CE, et al. Human Islet Expression Levels of Prostaglandin E Synthetic Enzymes, But Not Prostaglandin EP3 Receptor, Are Positively Correlated with Markers of β-Cell Function and Mass in Nondiabetic Obesity. Acs Pharmacology & Translational Science. 4: 1338-1348. PMID 34423270 DOI: 10.1021/acsptsci.1c00045   
2021 Ceddia RP, Liu D, Shi F, Crowder MK, Mishra S, Kass DA, Collins S. Increased Energy Expenditure and Protection from Diet-Induced Obesity in Mice Lacking the cGMP-Specific Phosphodiesterase PDE9. Diabetes. PMID 34620617 DOI: 10.2337/db21-0100   
2021 Atanasovska B, Rensen SS, Marsman G, Shiri-Sverdlov R, Withoff S, Kuipers F, Wijmenga C, van de Sluis B, Fu J. Long Non-Coding RNAs Involved in Progression of Non-Alcoholic Fatty Liver Disease to Steatohepatitis. Cells. 10. PMID 34440652 DOI: 10.3390/cells10081883   
2021 Subramanian VS, Teafatiller T, Moradi H, Marchant JS. Histone deacetylase inhibitors regulate vitamin C transporter functional expression in intestinal epithelial cells. The Journal of Nutritional Biochemistry. 108838. PMID 34403723 DOI: 10.1016/j.jnutbio.2021.108838   
2021 Lim JO, Lee SJ, Kim WI, Pak SW, Moon C, Shin IS, Heo JD, Ko JW, Kim JC. Titanium Dioxide Nanoparticles Exacerbate Allergic Airway Inflammation via TXNIP Upregulation in a Mouse Model of Asthma. International Journal of Molecular Sciences. 22. PMID 34576095 DOI: 10.3390/ijms22189924   
2021 Mao H, Li L, Fan Q, Angelini A, Saha PK, Coarfa C, Rajapakshe K, Perera D, Cheng J, Wu H, Ballantyne CM, Sun Z, Xie L, Pi X. Endothelium-specific depletion of LRP1 improves glucose homeostasis through inducing osteocalcin. Nature Communications. 12: 5296. PMID 34489478 DOI: 10.1038/s41467-021-25673-6