Giles S. H. Yeo, PhD - Related publications

Institute of Metabolic Science University of Cambridge, Cambridge, England, United Kingdom 
Metabolism, Genetics, Genomics
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Burchat N, Sharma P, Ye H, Komakula SSB, Dobrzyn A, Vartanian V, Lloyd RS, Sampath H. Maternal Transmission of Human OGG1 Protects Mice Against Genetically- and Diet-Induced Obesity Through Increased Tissue Mitochondrial Content. Frontiers in Cell and Developmental Biology. 9: 718962. PMID 34604220 DOI: 10.3389/fcell.2021.718962   
2021 Khan MI, Khan MZ, Shin JH, Shin TS, Lee YB, Kim MY, Kim JD. Pharmacological Approaches to Attenuate Inflammation and Obesity with Natural Products Formulations by Regulating the Associated Promoting Molecular Signaling Pathways. Biomed Research International. 2021: 2521273. PMID 34812408 DOI: 10.1155/2021/2521273   
2021 Yu M, Yue J, Hui N, Zhi Y, Hayat K, Yang X, Zhang D, Chu S, Zhou P. Anti-Hyperlipidemia and Gut Microbiota Community Regulation Effects of Selenium-Rich Polysaccharides on the High-Fat Diet-Fed Mice Model. Foods (Basel, Switzerland). 10. PMID 34681302 DOI: 10.3390/foods10102252   
2021 Zhang H, Cao W, Liu F, Gao Y, Chang Y, Xue C, Tang Q. The mechanism exploration of the non-colonic toxicity and obesity inhibition of food-grade κ-carrageenan by transcriptome. Food Science & Nutrition. 9: 6232-6244. PMID 34760253 DOI: 10.1002/fsn3.2581   
2021 Takaoka S, Yanagiya A, Mohamed HMA, Higa R, Abe T, Inoue KI, Takahashi A, Stoney P, Yamamoto T. Neuronal XRN1 is required for maintenance of whole-body metabolic homeostasis. Iscience. 24: 103151. PMID 34646989 DOI: 10.1016/j.isci.2021.103151   
2021 Ma T, Lu W, Wang Y, Qian P, Tian H, Gao X, Yao W. An oral GLP-1 and GIP dual receptor agonist improves metabolic disorders in high fat-fed mice. European Journal of Pharmacology. 174635. PMID 34800466 DOI: 10.1016/j.ejphar.2021.174635   
2021 Wang Y, Liu S, Tang D, Dong R, Feng Q. Chitosan Oligosaccharide Ameliorates Metabolic Syndrome Induced by Overnutrition Altering Intestinal Microbiota. Frontiers in Nutrition. 8: 743492. PMID 34660667 DOI: 10.3389/fnut.2021.743492   
2021 Le J, Fu Y, Han Q, Wei X, Ji H, Chen Y, Wang Q, Pi P, Li J, Lin X, Zhang X, Zhang Y, Ye J. Restoration of mRNA Expression of Solute Carrier Proteins in Liver of Diet-Induced Obese Mice by Metformin. Frontiers in Endocrinology. 12: 720784. PMID 34659115 DOI: 10.3389/fendo.2021.720784   
2021 Longenecker JZ, Petrosino JM, Martens CR, Hinger SA, Royer CJ, Dorn LE, Branch DA, Serrano J, Stanford KI, Kyriazis GA, Baskin KK, Accornero F. Cardiac-derived TGF-β1 confers resistance to diet-induced obesity through regulation of adipocyte size and function. Molecular Metabolism. 101343. PMID 34583010 DOI: 10.1016/j.molmet.2021.101343   
2021 Moura-Assis A, Nogueira PAS, de-Lima-Junior JC, Simabuco FM, Gaspar JM, Donato J, Velloso LA. TLR4-interactor with leucine-rich repeats (TRIL) is involved in diet-induced hypothalamic inflammation. Scientific Reports. 11: 18015. PMID 34504172 DOI: 10.1038/s41598-021-97291-7   
2021 Totten MS, Wallace CW, Pierce DM, Fordahl SC, Erikson KM. The impact of a high-fat diet on physical activity and dopamine neurochemistry in the striatum is sex and strain dependent in C57BL/6J and DBA/2J mice. Nutritional Neuroscience. 1-15. PMID 34693894 DOI: 10.1080/1028415X.2021.1992082   
2021 Huang L, Liu P, Yang Q, Wang YX. The KRAB Domain-Containing Protein ZFP961 Represses Adipose Thermogenesis and Energy Expenditure through Interaction with PPARα. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2102949. PMID 34747141 DOI: 10.1002/advs.202102949   
2021 Minderis P, Fokin A, Dirmontas M, Kvedaras M, Ratkevicius A. Caloric Restriction Rather Than Dietary Macronutrient Distribution Plays a Primary Role in Metabolic Health and Body Composition Improvements in Obese Mice. Nutrients. 13. PMID 34578880 DOI: 10.3390/nu13093004   
2021 Riddy DM, Kammoun HL, Murphy AJ, Bosnyak-Gladovic S, De la Fuente Gonzalez R, Merlin J, Ziemann M, Fabb S, Pierce TL, Diepenhorst N, Rueda P, El-Osta A, Gautier JF, Venteclef N, Charman WN, et al. Deletion of GPR21 improves glucose homeostasis and inhibits the CCL2-CCR2 axis by divergent mechanisms. Bmj Open Diabetes Research & Care. 9. PMID 34782333 DOI: 10.1136/bmjdrc-2021-002285   
2021 Fabersani E, Marquez A, Russo M, Ross R, Torres S, Fontana C, Puglisi E, Medina R, Gauffin-Cano P. Lactic Acid Bacteria Strains Differently Modulate Gut Microbiota and Metabolic and Immunological Parameters in High-Fat Diet-Fed Mice. Frontiers in Nutrition. 8: 718564. PMID 34568404 DOI: 10.3389/fnut.2021.718564   
2021 Mishra A, Mirzaei H, Guidi N, Vinciguerra M, Mouton A, Linardic M, Rappa F, Barone R, Navarrete G, Wei M, Brandhorst S, Di Biase S, Morgan TE, Ram Kumar S, Conti PS, et al. Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan. Nature Metabolism. PMID 34650272 DOI: 10.1038/s42255-021-00469-6   
2021 Chung JY, Hong J, Kim HJ, Song Y, Yong SB, Lee J, Kim YH. White adipocyte-targeted dual gene silencing of FABP4/5 for anti-obesity, anti-inflammation and reversal of insulin resistance: Efficacy and comparison of administration routes. Biomaterials. 279: 121209. PMID 34700224 DOI: 10.1016/j.biomaterials.2021.121209   
2021 Chen YC, Chien CY, Hsu CC, Lee CH, Chou YT, Shiah SG, Liu SY, Yen CY, Hsieh AC, Wabitsch M, Shieh YS. Obesity-associated leptin promotes chemoresistance in colorectal cancer through YAP-dependent AXL upregulation. American Journal of Cancer Research. 11: 4220-4240. PMID 34659884   
2021 Park YJ, Seo MG, Cominguez DC, Han I, An HJ. Water Extract Ameliorates Obesity via Promotion of the SIRT1/AMPK Expression in High-Fat Diet-Induced Obese Mice. Nutrients. 13. PMID 34578872 DOI: 10.3390/nu13092992   
2021 Wu C, Jeong MY, Kim JY, Lee G, Kim JS, Cheong YE, Kang H, Cho CH, Kim J, Park MK, Shin YK, Kim KH, Seol GH, Koo SH, Ko G, et al. Activation of ectopic olfactory receptor 544 induces GLP-1 secretion and regulates gut inflammation. Gut Microbes. 13: 1987782. PMID 34674602 DOI: 10.1080/19490976.2021.1987782   
2021 McCann MA, Li Y, Muñoz M, Gil V, Qiang G, Cordoba-Chacon J, Blüher M, Duncan S, Liew CW. Adipose expression of CREB3L3 modulates body weight during obesity. Scientific Reports. 11: 19400. PMID 34588527 DOI: 10.1038/s41598-021-98627-z   
2021 Pal A, Sun S, Armstrong M, Manke J, Reisdorph N, Adams VR, Kennedy A, Zu Y, Moustaid-Moussa N, Carroll I, Shaikh SR. Beneficial effects of eicosapentaenoic acid on the metabolic profile of obese female mice entails upregulation of HEPEs and increased abundance of enteric Akkermansia Muciniphila. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. 159059. PMID 34619367 DOI: 10.1016/j.bbalip.2021.159059   
2021 You D, Chul Jung B, Villivalam SD, Lim HW, Kang S. JMJD8 is a Novel Molecular Nexus Between Adipocyte-Intrinsic Inflammation and Insulin Resistance. Diabetes. PMID 34686520 DOI: 10.2337/db21-0596   
2021 Snyder MM, Yue F, Zhang L, Shang R, Qiu J, Chen J, Kim KH, Peng Y, Oprescu SN, Donkin SS, Bi P, Kuang S. LETMD1 is required for mitochondrial structure and thermogenic function of brown adipocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21965. PMID 34669999 DOI: 10.1096/fj.202100597R   
2021 Feng Z, Du Z, Shu X, Zhu L, Wu J, Gao Q, Wang L, Chen N, Li Y, Luo M, Hill MA, Wu J. Role of RAGE in obesity-induced adipose tissue inflammation and insulin resistance. Cell Death Discovery. 7: 305. PMID 34686659 DOI: 10.1038/s41420-021-00711-w   
2021 SantaCruz-Calvo S, Bharath L, Pugh G, SantaCruz-Calvo L, Lenin RR, Lutshumba J, Liu R, Bachstetter AD, Zhu B, Nikolajczyk BS. Adaptive immune cells shape obesity-associated type 2 diabetes mellitus and less prominent comorbidities. Nature Reviews. Endocrinology. PMID 34703027 DOI: 10.1038/s41574-021-00575-1   
2021 Lee HJ, Shi H, Brönneke HS, Jin BY, Choi SH, Seeley RJ, Kim DH. Vascular reactivity contributes to adipose tissue remodeling in obesity. The Journal of Endocrinology. PMID 34612845 DOI: 10.1530/JOE-21-0187   
2021 Gaur A, Pal GK, Pal P. Role of Ventromedial Hypothalamus in Sucrose-Induced Obesity on Metabolic Parameters. Annals of Neurosciences. 28: 39-46. PMID 34733053 DOI: 10.1177/09727531211005738   
2021 Cho K, Ushiki T, Ishiguro H, Tamura S, Araki M, Suwabe T, Katagiri T, Watanabe M, Fujimoto Y, Ohashi R, Ajioka Y, Shimizu I, Okuda S, Masuko M, Nakagawa Y, et al. Altered microbiota by a high-fat diet accelerates lethal myeloid hematopoiesis associated with systemic SOCS3 deficiency. Iscience. 24: 103117. PMID 34611611 DOI: 10.1016/j.isci.2021.103117   
2021 Hu S, Togo J, Wang L, Wu Y, Yang D, Xu Y, Li L, Li B, Li M, Li J, Wang G, Zhang X, Niu C, Mazidi M, Douglas A, et al. Effects of dietary macronutrients and body composition on glucose homeostasis in mice. National Science Review. 8: nwaa177. PMID 34691555 DOI: 10.1093/nsr/nwaa177   
2021 Ceddia RP, Liu D, Shi F, Crowder MK, Mishra S, Kass DA, Collins S. Increased Energy Expenditure and Protection from Diet-Induced Obesity in Mice Lacking the cGMP-Specific Phosphodiesterase PDE9. Diabetes. PMID 34620617 DOI: 10.2337/db21-0100   
2021 Torres DJ, Pitts MW, Seale LA, Hashimoto AC, An KJ, Hanato AN, Hui KW, Remigio SMA, Carlson BA, Hatfield DL, Berry MJ. Female Mice with Selenocysteine tRNA Deletion in Agrp Neurons Maintain Leptin Sensitivity and Resist Weight Gain While on a High-Fat Diet. International Journal of Molecular Sciences. 22. PMID 34681674 DOI: 10.3390/ijms222011010   
2021 Li X, Cai Y, Luo J, Ding J, Yao G, Xiao X, Tang Y, Liang Z. Metformin attenuates hypothalamic inflammation via downregulation of RIPK1-independent microglial necroptosis in diet-induced obese mice. Cell Death Discovery. 7: 338. PMID 34750365 DOI: 10.1038/s41420-021-00732-5   
2021 Chang GR, Hou PH, Wang CM, Lin JW, Lin WL, Lin TC, Liao HJ, Chan CH, Wang YC. Imipramine Accelerates Nonalcoholic Fatty Liver Disease, Renal Impairment, Diabetic Retinopathy, Insulin Resistance, and Urinary Chromium Loss in Obese Mice. Veterinary Sciences. 8. PMID 34564583 DOI: 10.3390/vetsci8090189   
2021 Yang B, Zheng F, Stanton C, Ross RP, Zhao J, Zhang H, Chen W. FYNLJ109L1 Attenuating Metabolic Syndrome in Mice via Gut Microbiota Modulation and Alleviating Inflammation. Foods (Basel, Switzerland). 10. PMID 34574191 DOI: 10.3390/foods10092081   
2021 Jouvet N, Bouyakdan K, Campbell SA, Baldwin C, Townsend SE, Gannon MA, Poitout V, Alquier T, Estall JL. The Tetracycline-Controlled Transactivator (Tet-On/Off) System in Beta Cells Reduces Insulin Expression and Secretion in Mice. Diabetes. PMID 34610983 DOI: 10.2337/db21-0147   
2021 Choi HN, Shin JY, Kim JI. Ameliorative Effect of Myricetin on Nonalcoholic Fatty Liver Disease in Mice. Journal of Medicinal Food. 24: 1092-1099. PMID 34668765 DOI: 10.1089/jmf.2021.K.0090   
2021 Zhao C, Cui X, Zhao Y, Qian B, Zhang N, Xin L, Ha C, Yang J, Wang X, Gao X. Impact of hepatocyte-specific deletion of staphylococcal nuclease and tudor domain containing 1 (SND1) on liver insulin resistance and acute liver failure of mice. Bioengineered. 12: 7360-7375. PMID 34608846 DOI: 10.1080/21655979.2021.1974653   
2021 Chun HJ, Shim YJ, Kwon YH. Cholic acid supplementation accelerates the progression of nonalcoholic fatty liver disease to the procarcinogenic state in mice fed a high-fat and high-cholesterol diet. The Journal of Nutritional Biochemistry. 108869. PMID 34563665 DOI: 10.1016/j.jnutbio.2021.108869   
2021 Wargent ET, Ahmad SJS, Lu QR, Kostenis E, Arch JRS, Stocker CJ. Leanness and Low Plasma Leptin in GPR17 Knockout Mice Are Dependent on Strain and Associated With Increased Energy Intake That Is Not Suppressed by Exogenous Leptin. Frontiers in Endocrinology. 12: 698115. PMID 34646232 DOI: 10.3389/fendo.2021.698115   
2021 Khang R, Jo A, Kang H, Kim H, Kwag E, Lee JY, Koo O, Park J, Kim HK, Jo DG, Hwang I, Ahn JY, Lee Y, Choi JY, Lee YS, et al. Loss of zinc-finger protein 212 leads to Purkinje cell death and locomotive abnormalities with phospholipase D3 downregulation. Scientific Reports. 11: 22745. PMID 34815492 DOI: 10.1038/s41598-021-02218-x   
2021 Lee H, Kim MH, Jin SC, Choi Y, Nam YK, Yang WM. LIPOSA pharmacopuncture, a new herbal formula, affects localized adiposity by regulating lipid metabolism . Experimental and Therapeutic Medicine. 22: 1290. PMID 34630645 DOI: 10.3892/etm.2021.10725   
2021 Huang T, Yu J, Ma Z, Fu Q, Liu S, Luo Z, Liu K, Yu L, Miao W, Yu D, Song Z, Li Y, Zhou L, Xu G. Translatomics Probes Into the Role of Lycopene on Improving Hepatic Steatosis Induced by High-Fat Diet. Frontiers in Nutrition. 8: 727785. PMID 34796193 DOI: 10.3389/fnut.2021.727785   
2021 Vomhof-DeKrey EE, Stover AD, Labuhn M, Osman MR, Basson MD. Vil-Cre specific Schlafen 3 knockout mice exhibit sex-specific differences in intestinal differentiation markers and Schlafen family members expression levels. Plos One. 16: e0259195. PMID 34710177 DOI: 10.1371/journal.pone.0259195   
2021 Deshycka R, Sudaryo V, Huang NJ, Xie Y, Smeding LY, Choi MK, Ploegh HL, Lodish HF, Pishesha N. Engineered red blood cells carrying PCSK9 inhibitors persistently lower LDL and prevent obesity. Plos One. 16: e0259353. PMID 34731223 DOI: 10.1371/journal.pone.0259353   
2021 Lee HB, Do MH, Jhun H, Ha SK, Song HS, Roh SW, Chung WH, Nam YD, Park HY. Amelioration of Hepatic Steatosis in Mice through CBA7346-Mediated Regulation of High-Fat Diet-Induced Insulin Resistance and Lipogenesis. Nutrients. 13. PMID 34578867 DOI: 10.3390/nu13092989   
2021 Huang HT, Chen PC, Chen PS, Chiu WT, Kuo YM, Tzeng SF. Inhibitory Effects of Trifluoperazine on Peripheral Proinflammatory Cytokine Expression and Hypothalamic Microglia Activation in Obese Mice Induced by Chronic Feeding With High-Fat-Diet. Frontiers in Cellular Neuroscience. 15: 752771. PMID 34764855 DOI: 10.3389/fncel.2021.752771   
2021 Mohan R, Jo S, Da Sol Chung E, Oribamise E, Lockridge A, Abrahante-Lloréns JE, Ruan HB, Yang XY, Alejandro EU. Pancreatic β-Cell O-GlcNAc Transferase Overexpression Increases Susceptibility to Metabolic Stressors in Female Mice. Cells. 10. PMID 34685781 DOI: 10.3390/cells10102801   
2021 Huang S, Cao L, Cheng H, Li D, Li Y, Wu Z. The blooming intersection of subfatin and metabolic syndrome. Reviews in Cardiovascular Medicine. 22: 799-805. PMID 34565078 DOI: 10.31083/j.rcm2203086   
2021 Chen Y, Su J, Yan Y, Zhao Q, Ma J, Zhu M, He X, Zhang B, Xu H, Yang X, Duan Y, Han J. Intermittent Fasting Inhibits High-Fat Diet-Induced Atherosclerosis by Ameliorating Hypercholesterolemia and Reducing Monocyte Chemoattraction. Frontiers in Pharmacology. 12: 719750. PMID 34658858 DOI: 10.3389/fphar.2021.719750